locus-tag	class	description
FOB70_RS00105	COG4789	Type iii secretion
FOB70_RS00110	COG4792	protein secretion
FOB70_RS00140	COG3710	Transcriptional regulator
FOB70_RS00155	COG4790	Type iii secretion
FOB70_RS00255	COG2916	Histone family protein nucleoid-structuring protein H-NS
FOB70_RS00275	COG2207	Transcriptional regulator
FOB70_RS00285	COG4172	Belongs to the ABC transporter superfamily
FOB70_RS00290	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOB70_RS00300	COG0747	negative chemotaxis
FOB70_RS00320	COG0804	urea catabolic process
FOB70_RS00405	COG0183	Belongs to the thiolase family
FOB70_RS00425	COG3746	phosphate-selective porin O and P
FOB70_RS00445	COG1028	Short-chain dehydrogenase reductase Sdr
FOB70_RS00470	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FOB70_RS00480	COG0625	glutathione transferase activity
FOB70_RS00495	COG1686	Belongs to the peptidase S11 family
FOB70_RS00520	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FOB70_RS00540	COG1278	Cold shock
FOB70_RS00545	COG1741	Belongs to the pirin family
FOB70_RS00550	COG4667	esterase of the alpha-beta hydrolase superfamily
FOB70_RS00585	COG0673	inositol 2-dehydrogenase activity
FOB70_RS00590	COG2194	sulfuric ester hydrolase activity
FOB70_RS00595	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FOB70_RS00605	COG2205	protein histidine kinase activity
FOB70_RS00610	COG0745	RESPONSE REGULATOR receiver
FOB70_RS00615	COG4221	oxidoreductase activity
FOB70_RS00635	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FOB70_RS00655	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FOB70_RS00665	COG2814	Major facilitator Superfamily
FOB70_RS00680	COG1418	mRNA catabolic process
FOB70_RS00690	COG0402	S-adenosylhomocysteine deaminase activity
FOB70_RS00695	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FOB70_RS00705	COG2239	Acts as a magnesium transporter
FOB70_RS00710	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FOB70_RS00725	COG0531	amino acid
FOB70_RS00735	COG1522	sequence-specific DNA binding
FOB70_RS00760	COG0784	Response regulator, receiver
FOB70_RS00760	COG2205	protein histidine kinase activity
FOB70_RS00760	COG5002	protein histidine kinase activity
FOB70_RS00765	COG0673	inositol 2-dehydrogenase activity
FOB70_RS00770	COG0534	Mate efflux family protein
FOB70_RS00775	COG2926	Belongs to the UPF0265 family
FOB70_RS00790	COG3132	Protein of unknown function, DUF480
FOB70_RS00795	COG2827	Endonuclease containing a URI domain
FOB70_RS00800	COG1879	ABC-type sugar transport system periplasmic component
FOB70_RS00805	COG0784	Response regulator, receiver
FOB70_RS00805	COG2205	protein histidine kinase activity
FOB70_RS00815	COG1566	PFAM secretion protein HlyD family protein
FOB70_RS00835	COG1522	sequence-specific DNA binding
FOB70_RS00865	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FOB70_RS00870	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FOB70_RS00890	COG0183	Belongs to the thiolase family
FOB70_RS00910	COG3005	denitrification pathway
FOB70_RS00920	COG0243	molybdopterin cofactor binding
FOB70_RS00930	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FOB70_RS00935	COG3850	Histidine kinase
FOB70_RS00940	COG2197	response regulator
FOB70_RS00955	COG2195	Cleaves the N-terminal amino acid of tripeptides
FOB70_RS00975	COG0840	transmembrane signaling receptor activity
FOB70_RS00985	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FOB70_RS01000	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FOB70_RS01005	COG2814	Major facilitator Superfamily
FOB70_RS01015	COG0840	transmembrane signaling receptor activity
FOB70_RS01020	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FOB70_RS01025	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FOB70_RS01055	COG2897	thiosulfate sulfurtransferase activity
FOB70_RS01075	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FOB70_RS01085	COG0302	gtp cyclohydrolase
FOB70_RS01090	COG1914	H( )-stimulated, divalent metal cation uptake system
FOB70_RS01100	COG0038	chloride channel
FOB70_RS01115	COG4989	oxidoreductase activity
FOB70_RS01130	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FOB70_RS01130	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FOB70_RS01135	COG0516	GMP reductase activity
FOB70_RS01140	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FOB70_RS01210	COG0674	pyruvate-flavodoxin oxidoreductase activity
FOB70_RS01210	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FOB70_RS01215	COG1013	pyruvate-flavodoxin oxidoreductase activity
FOB70_RS01220	COG3474	cytochrome
FOB70_RS01230	COG0789	Transcriptional regulator
FOB70_RS01235	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FOB70_RS01240	COG0384	phenazine biosynthesis protein PhzF
FOB70_RS01250	COG1294	oxidase, subunit
FOB70_RS01255	COG1271	oxidase subunit
FOB70_RS01260	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOB70_RS01265	COG0110	maltose O-acetyltransferase activity
FOB70_RS01275	COG3264	Mechanosensitive ion channel
FOB70_RS01275	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FOB70_RS01290	COG4999	Histidine kinase
FOB70_RS01290	COG2205	protein histidine kinase activity
FOB70_RS01290	COG3850	Histidine kinase
FOB70_RS01290	COG3437	response regulator, receiver
FOB70_RS01300	COG4770	biotin carboxylase activity
FOB70_RS01310	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FOB70_RS01315	COG1960	acyl-CoA dehydrogenase activity
FOB70_RS01325	COG0183	Belongs to the thiolase family
FOB70_RS01335	COG1960	acyl-CoA dehydrogenase activity
FOB70_RS01340	COG1024	Enoyl-CoA hydratase
FOB70_RS01365	COG3706	GGDEF domain
FOB70_RS01370	COG1309	transcriptional regulator
FOB70_RS01375	COG1012	belongs to the aldehyde dehydrogenase family
FOB70_RS01390	COG4176	ABC-type proline glycine betaine transport system permease component
FOB70_RS01395	COG4175	Glycine betaine
FOB70_RS01395	COG0517	IMP dehydrogenase activity
FOB70_RS01410	COG0330	HflC and HflK could
FOB70_RS01425	COG5001	Diguanylate cyclase
FOB70_RS01425	COG3300	MHYT domain
FOB70_RS01445	COG0784	Response regulator, receiver
FOB70_RS01445	COG2205	protein histidine kinase activity
FOB70_RS01505	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FOB70_RS01510	COG5001	Diguanylate cyclase
FOB70_RS01515	COG1869	D-ribose catabolic process
FOB70_RS01520	COG1129	ABC transporter
FOB70_RS01525	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOB70_RS01530	COG1879	ABC-type sugar transport system periplasmic component
FOB70_RS01535	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOB70_RS01540	COG1609	Transcriptional regulator
FOB70_RS01555	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
FOB70_RS01575	COG0745	RESPONSE REGULATOR receiver
FOB70_RS01590	COG1785	Belongs to the alkaline phosphatase family
FOB70_RS01620	COG0814	amino acid
FOB70_RS01630	COG0243	molybdopterin cofactor binding
FOB70_RS01635	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FOB70_RS01635	COG1648	precorrin-2 dehydrogenase activity
FOB70_RS01655	COG3707	response regulator
FOB70_RS01665	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FOB70_RS01670	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOB70_RS01675	COG1116	anion transmembrane transporter activity
FOB70_RS01680	COG2146	nitrite reductase [NAD(P)H] activity
FOB70_RS01680	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FOB70_RS01735	COG0515	serine threonine protein kinase
FOB70_RS01735	COG2815	serine threonine protein kinase
FOB70_RS01770	COG0631	protein serine/threonine phosphatase activity
FOB70_RS01840	COG0420	3'-5' exonuclease activity
FOB70_RS01845	COG0419	ATPase involved in DNA repair
FOB70_RS01865	COG3040	lipid binding
FOB70_RS01875	COG2814	Major facilitator Superfamily
FOB70_RS01885	COG1288	antiporter activity
FOB70_RS01900	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
FOB70_RS01915	COG2425	protein containing a von Willebrand factor type A (vWA) domain
FOB70_RS01935	COG0583	DNA-binding transcription factor activity
FOB70_RS01940	COG0277	FAD linked oxidase domain protein
FOB70_RS01960	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FOB70_RS02005	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FOB70_RS02005	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FOB70_RS02050	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FOB70_RS02055	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FOB70_RS02065	COG2116	formate transmembrane transporter activity
FOB70_RS02085	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FOB70_RS02120	COG0534	Mate efflux family protein
FOB70_RS02125	COG2205	protein histidine kinase activity
FOB70_RS02125	COG0745	RESPONSE REGULATOR receiver
FOB70_RS02125	COG3292	Two component regulator propeller
FOB70_RS02135	COG3118	belongs to the thioredoxin family
FOB70_RS02140	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOB70_RS02165	COG2271	Major facilitator Superfamily
FOB70_RS02170	COG3851	Histidine kinase
FOB70_RS02175	COG2197	response regulator
FOB70_RS02185	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FOB70_RS02190	COG0583	DNA-binding transcription factor activity
FOB70_RS02200	COG0243	molybdopterin cofactor binding
FOB70_RS02230	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOB70_RS02245	COG1328	CTP reductase activity
FOB70_RS02250	COG0602	queuosine metabolic process
FOB70_RS02255	COG0534	Mate efflux family protein
FOB70_RS02275	COG4067	protein conserved in archaea
FOB70_RS02275	COG0189	ligase activity
FOB70_RS02285	COG3111	PFAM Bacterial OB fold (BOF) protein
FOB70_RS02290	COG1492	cobalamin metabolic process
FOB70_RS02295	COG0725	ABC transporter, periplasmic molybdate-binding protein
FOB70_RS02300	COG4149	molybdate abc transporter
FOB70_RS02305	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FOB70_RS02315	COG4251	negative regulation of phosphorylation
FOB70_RS02315	COG2203	Gaf domain
FOB70_RS02315	COG5001	Diguanylate cyclase
FOB70_RS02315	COG3706	GGDEF domain
FOB70_RS02340	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FOB70_RS02345	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FOB70_RS02370	COG3140	Belongs to the UPF0181 family
FOB70_RS02375	COG0589	response to stress
FOB70_RS02390	COG0023	Translation Initiation Factor
FOB70_RS02400	COG1181	Belongs to the D-alanine--D-alanine ligase family
FOB70_RS02410	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOB70_RS02410	COG1042	CoA-binding domain protein
FOB70_RS02410	COG0045	succinate-CoA ligase (ADP-forming) activity
FOB70_RS02415	COG0583	DNA-binding transcription factor activity
FOB70_RS02420	COG4771	TonB-dependent receptor
FOB70_RS02420	COG1629	transport
FOB70_RS02430	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FOB70_RS02435	COG3447	MASE1 domain protein
FOB70_RS02435	COG5002	protein histidine kinase activity
FOB70_RS02435	COG5001	Diguanylate cyclase
FOB70_RS02440	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FOB70_RS02445	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FOB70_RS02450	COG1984	allophanate hydrolase subunit 2
FOB70_RS02460	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FOB70_RS02465	COG4181	ATPase activity
FOB70_RS02475	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FOB70_RS02480	COG5001	Diguanylate cyclase
FOB70_RS02480	COG3300	MHYT domain
FOB70_RS02490	COG0484	heat shock protein binding
FOB70_RS02515	COG4533	DNA binding
FOB70_RS02525	COG2050	protein possibly involved in aromatic compounds catabolism
FOB70_RS02540	COG2067	long-chain fatty acid transport protein
FOB70_RS02545	COG2267	carboxylic ester hydrolase activity
FOB70_RS02565	COG0861	Integral membrane protein TerC family
FOB70_RS02570	COG0737	Belongs to the 5'-nucleotidase family
FOB70_RS02575	COG3593	DNA synthesis involved in DNA repair
FOB70_RS02585	COG0583	DNA-binding transcription factor activity
FOB70_RS02590	COG2116	formate transmembrane transporter activity
FOB70_RS02595	COG2353	YceI-like domain
FOB70_RS02600	COG3038	cytochrome b561
FOB70_RS02615	COG4943	cyclic-guanylate-specific phosphodiesterase activity
FOB70_RS02620	COG0513	Belongs to the DEAD box helicase family
FOB70_RS02625	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
FOB70_RS02635	COG0840	transmembrane signaling receptor activity
FOB70_RS02645	COG0546	phosphoglycolate phosphatase activity
FOB70_RS02655	COG0784	Response regulator, receiver
FOB70_RS02655	COG3437	response regulator, receiver
FOB70_RS02675	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOB70_RS02680	COG2759	Belongs to the formate--tetrahydrofolate ligase family
FOB70_RS02685	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FOB70_RS02700	COG2207	Transcriptional regulator
FOB70_RS02705	COG1979	alcohol dehydrogenase
FOB70_RS02730	COG2271	Major facilitator Superfamily
FOB70_RS02735	COG0469	pyruvate kinase activity
FOB70_RS02740	COG1126	abc transporter atp-binding protein
FOB70_RS02745	COG0765	amino acid transport
FOB70_RS02750	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOB70_RS02755	COG0765	amino acid transport
FOB70_RS02760	COG2203	Gaf domain
FOB70_RS02760	COG2200	EAL domain
FOB70_RS02760	COG2199	diguanylate cyclase activity
FOB70_RS02780	COG1609	Transcriptional regulator
FOB70_RS02785	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOB70_RS02785	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOB70_RS02790	COG1105	Belongs to the carbohydrate kinase PfkB family
FOB70_RS02795	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOB70_RS02795	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOB70_RS02795	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
FOB70_RS02835	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FOB70_RS02840	COG0509	glycine decarboxylation via glycine cleavage system
FOB70_RS02845	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FOB70_RS02845	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FOB70_RS02860	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
FOB70_RS02865	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FOB70_RS02870	COG0583	DNA-binding transcription factor activity
FOB70_RS02875	COG2176	DNA-directed DNA polymerase activity
FOB70_RS02920	COG0242	peptide deformylase activity
FOB70_RS02950	COG2239	Acts as a magnesium transporter
FOB70_RS02970	COG0346	lactoylglutathione lyase activity
FOB70_RS02975	COG1902	pentaerythritol trinitrate reductase activity
FOB70_RS02995	COG5642	Protein of unknown function (DUF2384)
FOB70_RS03000	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FOB70_RS03020	COG4565	transcriptional regulatory protein
FOB70_RS03025	COG3290	protein histidine kinase activity
FOB70_RS03030	COG0471	metal ion transport
FOB70_RS03060	COG2076	Multidrug Resistance protein
FOB70_RS03075	COG0671	phosphoesterase, PA-phosphatase related
FOB70_RS03090	COG2962	Rard protein
FOB70_RS03110	COG0835	chemotaxis
FOB70_RS03110	COG0784	Response regulator, receiver
FOB70_RS03135	COG2197	response regulator
FOB70_RS03145	COG3706	GGDEF domain
FOB70_RS03150	COG2197	response regulator
FOB70_RS03155	COG3300	MHYT domain
FOB70_RS03155	COG5001	Diguanylate cyclase
FOB70_RS03170	COG0583	DNA-binding transcription factor activity
FOB70_RS03175	COG0583	DNA-binding transcription factor activity
FOB70_RS03235	COG4964	Belongs to the GSP D family
FOB70_RS03260	COG2207	Transcriptional regulator
FOB70_RS03280	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FOB70_RS03300	COG1214	PFAM Peptidase M22, glycoprotease
FOB70_RS03300	COG0456	acetyltransferase
FOB70_RS03310	COG3069	C4-dicarboxylate transmembrane transporter activity
FOB70_RS03315	COG1704	LemA family
FOB70_RS03320	COG0501	Belongs to the peptidase M48B family
FOB70_RS03350	COG0641	radical SAM
FOB70_RS03370	COG3111	PFAM Bacterial OB fold (BOF) protein
FOB70_RS03375	COG1597	lipid kinase activity
FOB70_RS03380	COG0583	DNA-binding transcription factor activity
FOB70_RS03385	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FOB70_RS03385	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FOB70_RS03415	COG0714	Associated with various cellular activities
FOB70_RS03420	COG0641	radical SAM
FOB70_RS03425	COG3119	arylsulfatase activity
FOB70_RS03440	COG3119	arylsulfatase activity
FOB70_RS03445	COG3119	arylsulfatase activity
FOB70_RS03450	COG0745	RESPONSE REGULATOR receiver
FOB70_RS03465	COG0784	Response regulator, receiver
FOB70_RS03465	COG2198	Histidine kinase
FOB70_RS03465	COG2205	protein histidine kinase activity
FOB70_RS03470	COG1879	ABC-type sugar transport system periplasmic component
FOB70_RS03475	COG1803	Methylglyoxal synthase
FOB70_RS03480	COG0210	DNA helicase
FOB70_RS03485	COG1289	transmembrane transporter activity
FOB70_RS03520	COG4771	TonB-dependent receptor
FOB70_RS03520	COG1629	transport
FOB70_RS03535	COG0789	Transcriptional regulator
FOB70_RS03540	COG4604	ABC transporter, ATP-binding protein
FOB70_RS03545	COG4605	iron ion homeostasis
FOB70_RS03550	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOB70_RS03555	COG4607	ABC-type enterochelin transport system periplasmic component
FOB70_RS03580	COG2847	Copper chaperone PCu(A)C
FOB70_RS03585	COG0443	Heat shock 70 kDa protein
FOB70_RS03620	COG0625	glutathione transferase activity
FOB70_RS03635	COG4160	amino acid transport
FOB70_RS03640	COG4215	(ABC) transporter
FOB70_RS03645	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOB70_RS03650	COG1126	abc transporter atp-binding protein
FOB70_RS03660	COG1902	pentaerythritol trinitrate reductase activity
FOB70_RS03665	COG0109	protoheme IX farnesyltransferase activity
FOB70_RS03670	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FOB70_RS03675	COG1845	cytochrome c oxidase, subunit III
FOB70_RS03680	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FOB70_RS03685	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FOB70_RS03690	COG1028	Short-chain dehydrogenase reductase Sdr
FOB70_RS03700	COG1024	Enoyl-CoA hydratase
FOB70_RS03705	COG1024	Enoyl-CoA hydratase
FOB70_RS03720	COG0183	Belongs to the thiolase family
FOB70_RS03730	COG1960	acyl-CoA dehydrogenase activity
FOB70_RS03735	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FOB70_RS03740	COG1024	Enoyl-CoA hydratase
FOB70_RS03750	COG5413	integral membrane protein
FOB70_RS03765	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FOB70_RS03775	COG5001	Diguanylate cyclase
FOB70_RS03780	COG0513	Belongs to the DEAD box helicase family
FOB70_RS03785	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
FOB70_RS03800	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FOB70_RS03820	COG0641	radical SAM
FOB70_RS03845	COG0840	transmembrane signaling receptor activity
FOB70_RS03850	COG1119	ATPase activity
FOB70_RS03855	COG2200	EAL domain
FOB70_RS03875	COG0513	Belongs to the DEAD box helicase family
FOB70_RS03880	COG0523	cobalamin synthesis protein
FOB70_RS03890	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
FOB70_RS03900	COG0133	tryptophan synthase activity
FOB70_RS03905	COG4628	conserved protein (DUF2132)
FOB70_RS03910	COG0513	Belongs to the DEAD box helicase family
FOB70_RS03915	COG3530	Putative quorum-sensing-regulated virulence factor
FOB70_RS03940	COG2154	pterin-4-alpha-carbinolamine dehydratase
FOB70_RS03945	COG3186	Phenylalanine-4-hydroxylase
FOB70_RS03950	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FOB70_RS03955	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FOB70_RS03990	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
FOB70_RS03995	COG1454	alcohol dehydrogenase
FOB70_RS04000	COG2133	pyrroloquinoline quinone binding
FOB70_RS04010	COG0783	Belongs to the Dps family
FOB70_RS04020	COG0840	transmembrane signaling receptor activity
FOB70_RS04030	COG1136	(ABC) transporter
FOB70_RS04030	COG0577	efflux transmembrane transporter activity
FOB70_RS04050	COG2199	diguanylate cyclase activity
FOB70_RS04065	COG3036	rescue of stalled ribosome
FOB70_RS04070	COG1278	Cold shock
FOB70_RS04105	COG0545	Peptidyl-prolyl cis-trans isomerase
FOB70_RS04110	COG0109	protoheme IX farnesyltransferase activity
FOB70_RS04115	COG1612	heme a metabolic process
FOB70_RS04140	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
FOB70_RS04150	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FOB70_RS04155	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FOB70_RS04165	COG1280	lysine exporter protein (LysE YggA)
FOB70_RS04170	COG2207	Transcriptional regulator
FOB70_RS04195	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FOB70_RS04200	COG0697	spore germination
FOB70_RS04225	COG2814	Major facilitator Superfamily
FOB70_RS04230	COG0583	DNA-binding transcription factor activity
FOB70_RS04235	COG5001	Diguanylate cyclase
FOB70_RS04240	COG0739	heme binding
FOB70_RS04265	COG3314	Sporulation integral membrane protein YlbJ
FOB70_RS04280	COG0814	amino acid
FOB70_RS04300	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FOB70_RS04305	COG1072	(Pantothenic acid kinase))
FOB70_RS04315	COG1063	alcohol dehydrogenase
FOB70_RS04320	COG2213	PTS system mannitol-specific
FOB70_RS04325	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOB70_RS04345	COG0798	PFAM Bile acid sodium symporter
FOB70_RS04355	COG1881	PFAM PEBP family protein
FOB70_RS04365	COG2706	6-phosphogluconolactonase activity
FOB70_RS04385	COG1131	(ABC) transporter
FOB70_RS04390	COG0842	Transport permease protein
FOB70_RS04405	COG3383	formate dehydrogenase (NAD+) activity
FOB70_RS04430	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOB70_RS04460	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOB70_RS04470	COG2067	long-chain fatty acid transport protein
FOB70_RS04480	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOB70_RS04490	COG1505	serine-type exopeptidase activity
FOB70_RS04495	COG0488	(ABC) transporter
FOB70_RS04500	COG0589	response to stress
FOB70_RS04505	COG2249	NAD(P)H dehydrogenase (quinone) activity
FOB70_RS04525	COG0366	Alpha amylase catalytic
FOB70_RS04535	COG4934	collagen metabolic process
FOB70_RS04550	COG0583	DNA-binding transcription factor activity
FOB70_RS04560	COG0783	Belongs to the Dps family
FOB70_RS04565	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FOB70_RS04600	COG2814	Major facilitator Superfamily
FOB70_RS04615	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FOB70_RS04620	COG0835	chemotaxis
FOB70_RS04620	COG0784	Response regulator, receiver
FOB70_RS04630	COG0748	coenzyme F420 binding
FOB70_RS04635	COG3721	Heme iron utilization protein
FOB70_RS04645	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
FOB70_RS04650	COG0811	peptide transport
FOB70_RS04655	COG0848	biopolymer transport protein
FOB70_RS04665	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOB70_RS04670	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FOB70_RS04715	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FOB70_RS04720	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FOB70_RS04725	COG0633	Ferredoxin
FOB70_RS04725	COG3217	Mosc domain protein beta barrel domain protein
FOB70_RS04725	COG3217	Mosc domain protein beta barrel domain protein
FOB70_RS04725	COG0633	Ferredoxin
FOB70_RS04735	COG0401	homolog of Blt101
FOB70_RS04745	COG0418	dihydroorotase activity
FOB70_RS04750	COG2354	Protein conserved in bacteria
FOB70_RS04780	COG2207	Transcriptional regulator
FOB70_RS04780	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOB70_RS04785	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOB70_RS04830	COG0513	Belongs to the DEAD box helicase family
FOB70_RS04840	COG0583	DNA-binding transcription factor activity
FOB70_RS04855	COG1902	pentaerythritol trinitrate reductase activity
FOB70_RS04860	COG1063	alcohol dehydrogenase
FOB70_RS04870	COG1028	Short-chain dehydrogenase reductase Sdr
FOB70_RS04885	COG3122	Protein conserved in bacteria
FOB70_RS04905	COG0583	DNA-binding transcription factor activity
FOB70_RS04910	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FOB70_RS04915	COG0252	asparaginase activity
FOB70_RS04920	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FOB70_RS04925	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FOB70_RS04925	COG0574	Belongs to the PEP-utilizing enzyme family
FOB70_RS04945	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FOB70_RS04965	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOB70_RS04985	COG3706	GGDEF domain
FOB70_RS05005	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FOB70_RS05035	COG3842	ATPase activity
FOB70_RS05090	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOB70_RS05140	COG0583	DNA-binding transcription factor activity
FOB70_RS05150	COG4948	Mandelate Racemase Muconate Lactonizing
FOB70_RS05185	COG1342	Belongs to the UPF0251 family
FOB70_RS05195	COG3015	lipoprotein NlpE involved in copper resistance
FOB70_RS05205	COG3713	MltA-interacting MipA family protein
FOB70_RS05220	COG0583	DNA-binding transcription factor activity
FOB70_RS05245	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FOB70_RS05255	COG1335	isochorismatase
FOB70_RS05265	COG0753	catalase activity
FOB70_RS05275	COG1349	DNA-binding transcription factor activity
FOB70_RS05280	COG0346	lactoylglutathione lyase activity
FOB70_RS05295	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOB70_RS05300	COG2070	2-Nitropropane dioxygenase
FOB70_RS05305	COG0737	Belongs to the 5'-nucleotidase family
FOB70_RS05315	COG1309	transcriptional regulator
FOB70_RS05335	COG1280	lysine exporter protein (LysE YggA)
FOB70_RS05350	COG0459	protein refolding
FOB70_RS05355	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FOB70_RS05365	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOB70_RS05390	COG1304	FMN binding
FOB70_RS05410	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FOB70_RS05425	COG1706	bacterial-type flagellum-dependent cell motility
FOB70_RS05430	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FOB70_RS05435	COG4786	Flagellar basal body rod
FOB70_RS05440	COG4787	bacterial-type flagellum-dependent cell motility
FOB70_RS05445	COG1749	Flagellar hook protein flgE
FOB70_RS05450	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FOB70_RS05455	COG1558	bacterial-type flagellum-dependent cell motility
FOB70_RS05460	COG1815	bacterial-type flagellum-dependent cell motility
FOB70_RS05480	COG0741	lytic transglycosylase activity
FOB70_RS05490	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FOB70_RS05510	COG1760	l-serine dehydratase
FOB70_RS05515	COG3104	oligopeptide transport
FOB70_RS05535	COG0583	DNA-binding transcription factor activity
FOB70_RS05550	COG2866	Carboxypeptidase
FOB70_RS05555	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOB70_RS05565	COG2990	Protein conserved in bacteria
FOB70_RS05590	COG3842	ATPase activity
FOB70_RS05600	COG1840	ABC-type Fe3 transport system, periplasmic component
FOB70_RS05605	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FOB70_RS05610	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FOB70_RS05615	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FOB70_RS05620	COG1609	Transcriptional regulator
FOB70_RS05650	COG3240	lipase activity
FOB70_RS05660	COG0577	efflux transmembrane transporter activity
FOB70_RS05660	COG1136	(ABC) transporter
FOB70_RS05665	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOB70_RS05670	COG2067	long-chain fatty acid transport protein
FOB70_RS05680	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
FOB70_RS05695	COG1011	Hydrolase
FOB70_RS05735	COG0110	maltose O-acetyltransferase activity
FOB70_RS05740	COG1765	OsmC-like protein
FOB70_RS05745	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FOB70_RS05745	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FOB70_RS05760	COG3046	protein related to deoxyribodipyrimidine photolyase
FOB70_RS05765	COG0415	Belongs to the DNA photolyase family
FOB70_RS05770	COG3706	GGDEF domain
FOB70_RS05785	COG0840	transmembrane signaling receptor activity
FOB70_RS05790	COG3706	GGDEF domain
FOB70_RS05805	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOB70_RS05825	COG3033	Beta-eliminating lyase
FOB70_RS05835	COG0579	oxidoreductase
FOB70_RS05860	COG1114	Component of the transport system for branched-chain amino acids
FOB70_RS05865	COG3706	GGDEF domain
FOB70_RS05910	COG0583	DNA-binding transcription factor activity
FOB70_RS05915	COG0189	ligase activity
FOB70_RS05920	COG0189	ligase activity
FOB70_RS05920	COG4067	protein conserved in archaea
FOB70_RS05930	COG1166	arginine decarboxylase activity
FOB70_RS05935	COG0010	Belongs to the arginase family
FOB70_RS05940	COG2814	Major facilitator Superfamily
FOB70_RS05945	COG1770	oligopeptidase
FOB70_RS05960	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FOB70_RS05965	COG1121	(ABC) transporter
FOB70_RS05970	COG0803	Belongs to the bacterial solute-binding protein 9 family
FOB70_RS06015	COG0848	biopolymer transport protein
FOB70_RS06020	COG0811	peptide transport
FOB70_RS06025	COG0811	peptide transport
FOB70_RS06045	COG0745	RESPONSE REGULATOR receiver
FOB70_RS06050	COG0039	L-malate dehydrogenase activity
FOB70_RS06055	COG0584	glycerophosphoryl diester phosphodiesterase
FOB70_RS06065	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FOB70_RS06125	COG1901	pseudouridine methyltransferase
FOB70_RS06130	COG0312	modulator of DNA gyrase
FOB70_RS06135	COG0312	modulator of DNA gyrase
FOB70_RS06145	COG0351	phosphomethylpyrimidine kinase
FOB70_RS06150	COG1116	anion transmembrane transporter activity
FOB70_RS06155	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOB70_RS06160	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FOB70_RS06165	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FOB70_RS06170	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
FOB70_RS06175	COG0352	thiamine-phosphate diphosphorylase activity
FOB70_RS06185	COG0243	molybdopterin cofactor binding
FOB70_RS06190	COG3005	denitrification pathway
FOB70_RS06200	COG1028	Short-chain dehydrogenase reductase Sdr
FOB70_RS06215	COG0454	-acetyltransferase
FOB70_RS06215	COG0456	acetyltransferase
FOB70_RS06235	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOB70_RS06240	COG1929	Belongs to the glycerate kinase type-1 family
FOB70_RS06245	COG2610	gluconate transmembrane transporter activity
FOB70_RS06250	COG3835	regulator
FOB70_RS06275	COG0546	phosphoglycolate phosphatase activity
FOB70_RS06290	COG0583	DNA-binding transcription factor activity
FOB70_RS06300	COG0583	DNA-binding transcription factor activity
FOB70_RS06310	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
FOB70_RS06315	COG3408	Glycogen debranching enzyme
FOB70_RS06315	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
FOB70_RS06345	COG3047	cAMP biosynthetic process
FOB70_RS06350	COG1357	PFAM Pentapeptide repeats (8 copies)
FOB70_RS06380	COG2375	cellular response to nickel ion
FOB70_RS06385	COG0823	Involved in the tonB-independent uptake of proteins
FOB70_RS06390	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FOB70_RS06410	COG0800	Aldolase
FOB70_RS06415	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOB70_RS06430	COG1917	Cupin 2, conserved barrel domain protein
FOB70_RS06440	COG1028	Short-chain dehydrogenase reductase Sdr
FOB70_RS06445	COG1414	Transcriptional regulator
FOB70_RS06460	COG0583	DNA-binding transcription factor activity
FOB70_RS06465	COG2162	N-hydroxyarylamine O-acetyltransferase activity
FOB70_RS06470	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FOB70_RS06485	COG2199	diguanylate cyclase activity
FOB70_RS06495	COG0561	phosphatase activity
FOB70_RS06500	COG0583	DNA-binding transcription factor activity
FOB70_RS06515	COG0564	pseudouridine synthase activity
FOB70_RS06520	COG0534	Mate efflux family protein
FOB70_RS06530	COG5001	Diguanylate cyclase
FOB70_RS06540	COG3123	guanosine phosphorylase activity
FOB70_RS06580	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOB70_RS06590	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FOB70_RS06595	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FOB70_RS06610	COG2259	Doxx family
FOB70_RS06615	COG1741	Belongs to the pirin family
FOB70_RS06635	COG0363	glucosamine-6-phosphate deaminase activity
FOB70_RS06650	COG0786	glutamate:sodium symporter activity
FOB70_RS06655	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOB70_RS06660	COG1131	(ABC) transporter
FOB70_RS06670	COG0786	glutamate:sodium symporter activity
FOB70_RS06705	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FOB70_RS06715	COG3279	Response regulator of the LytR AlgR family
FOB70_RS06720	COG3275	phosphorelay sensor kinase activity
FOB70_RS06740	COG1136	(ABC) transporter
FOB70_RS06755	COG0772	Belongs to the SEDS family
FOB70_RS06760	COG0217	transcriptional regulatory protein
FOB70_RS06785	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
FOB70_RS06785	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FOB70_RS06795	COG0444	Belongs to the ABC transporter superfamily
FOB70_RS06800	COG4608	Belongs to the ABC transporter superfamily
FOB70_RS06825	COG1444	tRNA N-acetyltransferase activity
FOB70_RS06845	COG3340	Belongs to the peptidase S51 family
FOB70_RS06850	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FOB70_RS06855	COG1263	PTS System
FOB70_RS06855	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOB70_RS06860	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FOB70_RS06880	COG4166	transmembrane transport
FOB70_RS06925	COG0259	pyridoxamine-phosphate oxidase activity
FOB70_RS06955	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FOB70_RS07000	COG1132	(ABC) transporter
FOB70_RS07010	COG2207	Transcriptional regulator
FOB70_RS07035	COG0800	Aldolase
FOB70_RS07040	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOB70_RS07045	COG1904	glucuronate isomerase
FOB70_RS07050	COG0246	Mannitol dehydrogenase
FOB70_RS07060	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FOB70_RS07070	COG2186	Transcriptional regulator
FOB70_RS07080	COG0513	Belongs to the DEAD box helicase family
FOB70_RS07085	COG2258	MOSC domain
FOB70_RS07100	COG1486	melibiose metabolic process
FOB70_RS07105	COG0583	DNA-binding transcription factor activity
FOB70_RS07125	COG1595	DNA-templated transcription, initiation
FOB70_RS07160	COG3634	alkyl hydroperoxide reductase activity
FOB70_RS07170	COG1846	Transcriptional regulator
FOB70_RS07175	COG1764	response to oxidative stress
FOB70_RS07200	COG2160	L-arabinose isomerase activity
FOB70_RS07210	COG1069	ribulokinase activity
FOB70_RS07215	COG1879	ABC-type sugar transport system periplasmic component
FOB70_RS07220	COG1129	ABC transporter
FOB70_RS07225	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOB70_RS07230	COG0826	peptidase U32
FOB70_RS07260	COG1653	transport
FOB70_RS07265	COG0019	diaminopimelate decarboxylase activity
FOB70_RS07270	COG4264	IucA IucC family
FOB70_RS07295	COG4772	TonB-dependent receptor
FOB70_RS07300	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FOB70_RS07305	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOB70_RS07310	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOB70_RS07315	COG1120	ATPase activity
FOB70_RS07320	COG0840	transmembrane signaling receptor activity
FOB70_RS07325	COG0612	Peptidase, M16
FOB70_RS07335	COG0739	heme binding
FOB70_RS07360	COG4580	involved in the transport of maltose and maltodextrins
FOB70_RS07385	COG2356	endonuclease I
FOB70_RS07405	COG1982	Orn Lys Arg decarboxylase major
FOB70_RS07410	COG0531	amino acid
FOB70_RS07420	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
FOB70_RS07430	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
FOB70_RS07435	COG1162	GTPase activity
FOB70_RS07440	COG1263	PTS System
FOB70_RS07440	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOB70_RS07450	COG1999	signal sequence binding
FOB70_RS07465	COG2909	trisaccharide binding
FOB70_RS07480	COG0058	SHG alpha-glucan phosphorylase activity
FOB70_RS07485	COG1640	4-alpha-glucanotransferase
FOB70_RS07490	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FOB70_RS07495	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOB70_RS07500	COG0366	Alpha amylase catalytic
FOB70_RS07515	COG3366	ferrous iron transmembrane transporter activity
FOB70_RS07520	COG0700	Nucleoside recognition
FOB70_RS07525	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOB70_RS07530	COG3339	Conserved Protein
FOB70_RS07535	COG1301	dicarboxylic acid transport
FOB70_RS07545	COG0583	DNA-binding transcription factor activity
FOB70_RS07560	COG3206	protein involved in exopolysaccharide biosynthesis
FOB70_RS07560	COG0489	protein tyrosine kinase activity
FOB70_RS07580	COG2095	MarC family integral membrane protein
FOB70_RS07585	COG4667	esterase of the alpha-beta hydrolase superfamily
FOB70_RS07590	COG3397	chitin binding
FOB70_RS07595	COG1054	Belongs to the UPF0176 family
FOB70_RS07610	COG1686	Belongs to the peptidase S11 family
FOB70_RS07635	COG0583	DNA-binding transcription factor activity
FOB70_RS07640	COG4628	conserved protein (DUF2132)
FOB70_RS07650	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FOB70_RS07660	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
FOB70_RS07665	COG0628	permease
FOB70_RS07710	COG2814	Major facilitator Superfamily
FOB70_RS07725	COG0454	-acetyltransferase
FOB70_RS07735	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FOB70_RS07740	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FOB70_RS07745	COG1882	Formate acetyltransferase
FOB70_RS07795	COG1360	Flagellar Motor Protein
FOB70_RS07800	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FOB70_RS07805	COG1191	sigma factor activity
FOB70_RS07810	COG1580	Controls the rotational direction of flagella during chemotaxis
FOB70_RS07825	COG1516	flagellar protein fliS
FOB70_RS07830	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FOB70_RS07840	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FOB70_RS07855	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FOB70_RS07865	COG1987	bacterial-type flagellum assembly
FOB70_RS07945	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FOB70_RS07965	COG0346	lactoylglutathione lyase activity
FOB70_RS08000	COG0745	RESPONSE REGULATOR receiver
FOB70_RS08020	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOB70_RS08030	COG0156	8-amino-7-oxononanoate synthase activity
FOB70_RS08035	COG1063	alcohol dehydrogenase
FOB70_RS08070	COG0668	transmembrane transport
FOB70_RS08080	COG1304	FMN binding
FOB70_RS08085	COG1620	l-lactate permease
FOB70_RS08090	COG0583	DNA-binding transcription factor activity
FOB70_RS08095	COG1505	serine-type exopeptidase activity
FOB70_RS08100	COG4172	Belongs to the ABC transporter superfamily
FOB70_RS08110	COG1067	ATP-dependent peptidase activity
FOB70_RS08140	COG1247	-acetyltransferase
FOB70_RS08145	COG0437	4 iron, 4 sulfur cluster binding
FOB70_RS08150	COG0348	domain, Protein
FOB70_RS08165	COG1122	ATPase activity
FOB70_RS08170	COG4720	Psort location CytoplasmicMembrane, score
FOB70_RS08175	COG1566	PFAM secretion protein HlyD family protein
FOB70_RS08185	COG3706	GGDEF domain
FOB70_RS08200	COG0813	purine-nucleoside phosphorylase activity
FOB70_RS08210	COG3272	Protein of unknown function (DUF1722)
FOB70_RS08215	COG0789	Transcriptional regulator
FOB70_RS08220	COG0415	Belongs to the DNA photolyase family
FOB70_RS08225	COG1388	LysM domain
FOB70_RS08225	COG1376	ErfK ybiS ycfS ynhG family protein
FOB70_RS08235	COG0513	Belongs to the DEAD box helicase family
FOB70_RS08240	COG1770	oligopeptidase
FOB70_RS08245	COG4771	TonB-dependent receptor
FOB70_RS08275	COG0573	inorganic phosphate transmembrane transporter activity
FOB70_RS08280	COG0581	inorganic phosphate transmembrane transporter activity
FOB70_RS08285	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FOB70_RS08300	COG2304	oxidoreductase activity
FOB70_RS08320	COG0714	Associated with various cellular activities
FOB70_RS08330	COG0840	transmembrane signaling receptor activity
FOB70_RS08340	COG2197	response regulator
FOB70_RS08390	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FOB70_RS08395	COG1120	ATPase activity
FOB70_RS08400	COG4774	siderophore transport
FOB70_RS08405	COG1132	(ABC) transporter
FOB70_RS08410	COG2205	protein histidine kinase activity
FOB70_RS08420	COG0569	domain protein
FOB70_RS08425	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FOB70_RS08430	COG5001	Diguanylate cyclase
FOB70_RS08430	COG3300	MHYT domain
FOB70_RS08435	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
FOB70_RS08440	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FOB70_RS08455	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOB70_RS08455	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOB70_RS08455	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOB70_RS08460	COG2207	Transcriptional regulator
FOB70_RS08470	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOB70_RS08475	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOB70_RS08480	COG2084	Dehydrogenase
FOB70_RS08485	COG0753	catalase activity
FOB70_RS08495	COG2130	NADP-dependent
FOB70_RS08500	COG1309	transcriptional regulator
FOB70_RS08505	COG3097	Belongs to the UPF0267 family
FOB70_RS08565	COG3842	ATPase activity
FOB70_RS08575	COG1175	transmembrane transport
FOB70_RS08580	COG3833	ABC-type maltose transport systems, permease component
FOB70_RS08670	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FOB70_RS08725	COG2202	Pas domain
FOB70_RS08725	COG2200	EAL domain
FOB70_RS08725	COG2199	diguanylate cyclase activity
FOB70_RS08740	COG2813	Specifically methylates the guanine in position
FOB70_RS08745	COG0628	permease
FOB70_RS08750	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FOB70_RS08755	COG0316	Belongs to the HesB IscA family
FOB70_RS08765	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOB70_RS08770	COG0739	heme binding
FOB70_RS08775	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FOB70_RS08785	COG2027	D-alanyl-D-alanine carboxypeptidase
FOB70_RS08790	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FOB70_RS08795	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FOB70_RS08800	COG1534	Rna-binding protein
FOB70_RS08805	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FOB70_RS08810	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FOB70_RS08815	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FOB70_RS08820	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FOB70_RS08830	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FOB70_RS08845	COG0779	Required for maturation of 30S ribosomal subunits
FOB70_RS08850	COG0195	Participates in both transcription termination and antitermination
FOB70_RS08855	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FOB70_RS08860	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FOB70_RS08865	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FOB70_RS08870	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FOB70_RS08875	COG1185	polyribonucleotide nucleotidyltransferase activity
FOB70_RS08890	COG0534	Mate efflux family protein
FOB70_RS08895	COG0826	peptidase U32
FOB70_RS08900	COG0826	peptidase U32
FOB70_RS08910	COG3154	lipid carrier protein
FOB70_RS08915	COG3153	acetyltransferase
FOB70_RS08935	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FOB70_RS08945	COG0084	hydrolase, TatD family'
FOB70_RS08950	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOB70_RS08955	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FOB70_RS08960	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FOB70_RS08965	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FOB70_RS08970	COG0813	purine-nucleoside phosphorylase activity
FOB70_RS08980	COG0560	Phosphoserine phosphatase
FOB70_RS08990	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FOB70_RS08995	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FOB70_RS09000	COG0583	DNA-binding transcription factor activity
FOB70_RS09010	COG1022	Amp-dependent synthetase and ligase
FOB70_RS09015	COG2169	Transcriptional regulator
FOB70_RS09040	COG4964	Belongs to the GSP D family
FOB70_RS09100	COG0583	DNA-binding transcription factor activity
FOB70_RS09105	COG0531	amino acid
FOB70_RS09110	COG2731	YhcH YjgK YiaL family protein
FOB70_RS09115	COG3250	beta-galactosidase activity
FOB70_RS09120	COG1609	Transcriptional regulator
FOB70_RS09130	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FOB70_RS09140	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FOB70_RS09145	COG2017	converts alpha-aldose to the beta-anomer
FOB70_RS09160	COG2211	Major facilitator Superfamily
FOB70_RS09165	COG1609	Transcriptional regulator
FOB70_RS09170	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOB70_RS09185	COG0598	Magnesium transport protein CorA
FOB70_RS09190	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FOB70_RS09195	COG1349	DNA-binding transcription factor activity
FOB70_RS09200	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FOB70_RS09205	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FOB70_RS09220	COG2271	Major facilitator Superfamily
FOB70_RS09225	COG0584	glycerophosphoryl diester phosphodiesterase
FOB70_RS09230	COG2171	N-acyltransferase activity
FOB70_RS09235	COG3141	response to X-ray
FOB70_RS09255	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FOB70_RS09265	COG1074	ATP-dependent DNA helicase activity
FOB70_RS09270	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FOB70_RS09295	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FOB70_RS09295	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FOB70_RS09310	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FOB70_RS09315	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FOB70_RS09320	COG2166	iron-sulfur cluster assembly
FOB70_RS09325	COG3706	GGDEF domain
FOB70_RS09330	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FOB70_RS09335	COG0693	protein deglycase activity
FOB70_RS09340	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FOB70_RS09365	COG1595	DNA-templated transcription, initiation
FOB70_RS09385	COG3056	Lipoprotein
FOB70_RS09390	COG2813	Specifically methylates the guanine in position
FOB70_RS09395	COG0271	Belongs to the BolA IbaG family
FOB70_RS09400	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FOB70_RS09405	COG1805	sodium ion transport
FOB70_RS09410	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FOB70_RS09415	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FOB70_RS09420	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FOB70_RS09425	COG2871	sodium ion transport
FOB70_RS09430	COG1477	protein flavinylation
FOB70_RS09445	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FOB70_RS09450	COG0514	ATP-dependent DNA helicase (RecQ)
FOB70_RS09455	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FOB70_RS09470	COG0733	neurotransmitter:sodium symporter activity
FOB70_RS09490	COG0442	prolyl-tRNA aminoacylation
FOB70_RS09495	COG1720	tRNA m6t6A37 methyltransferase activity
FOB70_RS09500	COG0254	rRNA binding
FOB70_RS09515	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
FOB70_RS09520	COG1671	Belongs to the UPF0178 family
FOB70_RS09545	COG3098	single-species biofilm formation
FOB70_RS09550	COG0564	pseudouridine synthase activity
FOB70_RS09560	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FOB70_RS09565	COG0024	Methionine aminopeptidase
FOB70_RS09570	COG0052	Belongs to the universal ribosomal protein uS2 family
FOB70_RS09575	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FOB70_RS09580	COG0528	UMP kinase activity
FOB70_RS09585	COG0233	cytoplasmic translational termination
FOB70_RS09590	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FOB70_RS09595	COG0575	Belongs to the CDS family
FOB70_RS09600	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FOB70_RS09605	COG0750	zinc metalloprotease
FOB70_RS09615	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
FOB70_RS09620	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FOB70_RS09625	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FOB70_RS09630	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FOB70_RS09635	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FOB70_RS09640	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FOB70_RS09645	COG0587	DNA-directed DNA polymerase activity
FOB70_RS09650	COG0825	malonyl-CoA metabolic process
FOB70_RS09655	COG0037	tRNA processing
FOB70_RS09665	COG0347	Belongs to the P(II) protein family
FOB70_RS09670	COG3021	interspecies interaction between organisms
FOB70_RS09680	COG1388	LysM domain
FOB70_RS09680	COG0741	lytic transglycosylase activity
FOB70_RS09685	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOB70_RS09690	COG2226	methyltransferase
FOB70_RS09695	COG0328	RNA-DNA hybrid ribonuclease activity
FOB70_RS09700	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FOB70_RS09715	COG1960	acyl-CoA dehydrogenase activity
FOB70_RS09720	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FOB70_RS09725	COG0121	glutamine amidotransferase
FOB70_RS09730	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FOB70_RS09735	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FOB70_RS09740	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FOB70_RS09745	COG2233	PERMEase
FOB70_RS09765	COG1393	Belongs to the ArsC family
FOB70_RS09770	COG4783	chaperone-mediated protein folding
FOB70_RS09785	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FOB70_RS09790	COG2716	regulation of RNA biosynthetic process
FOB70_RS09795	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FOB70_RS09800	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
FOB70_RS09815	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOB70_RS09820	COG1393	Belongs to the ArsC family
FOB70_RS09850	COG2837	iron assimilation
FOB70_RS09855	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FOB70_RS09865	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FOB70_RS09870	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FOB70_RS09875	COG1334	flagellar protein FlaG
FOB70_RS09880	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FOB70_RS09890	COG1516	flagellar protein fliS
FOB70_RS09910	COG1677	Flagellar hook-basal body complex protein FliE
FOB70_RS09920	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FOB70_RS09970	COG1987	bacterial-type flagellum assembly
FOB70_RS09975	COG1684	flagellar biosynthetic protein fliR
FOB70_RS10010	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
FOB70_RS10015	COG0643	Histidine kinase
FOB70_RS10015	COG0784	Response regulator, receiver
FOB70_RS10015	COG2198	Histidine kinase
FOB70_RS10020	COG2201	protein-glutamate methylesterase activity
FOB70_RS10025	COG1192	Involved in chromosome partitioning
FOB70_RS10035	COG0835	chemotaxis
FOB70_RS10045	COG4133	protoheme IX ABC transporter activity
FOB70_RS10050	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FOB70_RS10055	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FOB70_RS10060	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FOB70_RS10065	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
FOB70_RS10070	COG1138	Cytochrome C-type biogenesis protein
FOB70_RS10075	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOB70_RS10090	COG2853	Lipoprotein
FOB70_RS10095	COG2067	long-chain fatty acid transport protein
FOB70_RS10100	COG2067	long-chain fatty acid transport protein
FOB70_RS10120	COG0183	Belongs to the thiolase family
FOB70_RS10125	COG1024	Enoyl-CoA hydratase
FOB70_RS10125	COG1250	3-hydroxyacyl-CoA dehydrogenase
FOB70_RS10140	COG2062	phosphohistidine phosphatase, SixA
FOB70_RS10145	COG2840	Smr protein MutS2
FOB70_RS10150	COG2890	protein-(glutamine-N5) methyltransferase activity
FOB70_RS10155	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FOB70_RS10160	COG2860	membrane
FOB70_RS10170	COG3101	peptidyl-lysine hydroxylation
FOB70_RS10185	COG0431	NADPH-dependent FMN reductase
FOB70_RS10190	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FOB70_RS10190	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOB70_RS10195	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FOB70_RS10205	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FOB70_RS10210	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FOB70_RS10220	COG0101	tRNA pseudouridine synthase activity
FOB70_RS10225	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FOB70_RS10230	COG0285	dihydrofolate synthase activity
FOB70_RS10235	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
FOB70_RS10240	COG1286	toxin biosynthetic process
FOB70_RS10245	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FOB70_RS10250	COG0583	DNA-binding transcription factor activity
FOB70_RS10255	COG0745	RESPONSE REGULATOR receiver
FOB70_RS10265	COG2832	Protein of unknown function (DUF454)
FOB70_RS10270	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FOB70_RS10280	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FOB70_RS10285	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FOB70_RS10290	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FOB70_RS10295	COG0814	amino acid
FOB70_RS10300	COG0251	oxidation-reduction process
FOB70_RS10305	COG3681	Belongs to the UPF0597 family
FOB70_RS10320	COG2261	transglycosylase associated protein
FOB70_RS10325	COG2983	Belongs to the UPF0260 family
FOB70_RS10330	COG0668	transmembrane transport
FOB70_RS10335	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
FOB70_RS10340	COG0346	lactoylglutathione lyase activity
FOB70_RS10350	COG1785	Belongs to the alkaline phosphatase family
FOB70_RS10370	COG2226	methyltransferase
FOB70_RS10385	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FOB70_RS10390	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FOB70_RS10400	COG3139	Protein of unknown function (DUF1315)
FOB70_RS10405	COG0252	asparaginase activity
FOB70_RS10410	COG0616	signal peptide processing
FOB70_RS10415	COG0446	pyridine nucleotide-disulphide oxidoreductase
FOB70_RS10415	COG1902	pentaerythritol trinitrate reductase activity
FOB70_RS10420	COG0778	Nitroreductase
FOB70_RS10425	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FOB70_RS10445	COG0123	including yeast histone deacetylase and acetoin utilization protein
FOB70_RS10455	COG3083	sulfuric ester hydrolase activity
FOB70_RS10460	COG3082	Protein of unknown function (DUF1414)
FOB70_RS10465	COG3081	Nucleoid-associated protein
FOB70_RS10480	COG1757	Na H antiporter
FOB70_RS10485	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FOB70_RS10490	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FOB70_RS10495	COG2095	MarC family integral membrane protein
FOB70_RS10500	COG1012	belongs to the aldehyde dehydrogenase family
FOB70_RS10500	COG1454	alcohol dehydrogenase
FOB70_RS10520	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FOB70_RS10530	COG2056	Na+-H+ antiporter family
FOB70_RS10535	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FOB70_RS10550	COG2885	chlorophyll binding
FOB70_RS10560	COG0346	lactoylglutathione lyase activity
FOB70_RS10565	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FOB70_RS10570	COG4660	Part of a membrane complex involved in electron transport
FOB70_RS10575	COG4659	FMN binding
FOB70_RS10580	COG4658	electron transport chain
FOB70_RS10585	COG4656	Part of a membrane complex involved in electron transport
FOB70_RS10590	COG2878	Part of a membrane complex involved in electron transport
FOB70_RS10595	COG4657	Part of a membrane complex involved in electron transport
FOB70_RS10610	COG0556	nucleotide-excision repair
FOB70_RS10615	COG2204	response regulator
FOB70_RS10620	COG2198	Histidine kinase
FOB70_RS10625	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FOB70_RS10630	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FOB70_RS10635	COG0521	Mo-molybdopterin cofactor biosynthetic process
FOB70_RS10640	COG0315	cyclic pyranopterin monophosphate synthase activity
FOB70_RS10645	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FOB70_RS10650	COG0314	molybdopterin synthase activity
FOB70_RS10660	COG0601	transmembrane transport
FOB70_RS10665	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOB70_RS10670	COG0444	Belongs to the ABC transporter superfamily
FOB70_RS10680	COG0435	Glutathione S-transferase
FOB70_RS10690	COG3174	membrane
FOB70_RS10695	COG0280	phosphate acetyltransferase
FOB70_RS10695	COG0857	belongs to the CobB CobQ family
FOB70_RS10700	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FOB70_RS10705	COG3092	negative regulation of chromosome organization
FOB70_RS10715	COG4120	Belongs to the binding-protein-dependent transport system permease family
FOB70_RS10720	COG1122	ATPase activity
FOB70_RS10725	COG0366	Alpha amylase catalytic
FOB70_RS10735	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FOB70_RS10740	COG0653	protein targeting
FOB70_RS10745	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FOB70_RS10750	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FOB70_RS10755	COG2186	Transcriptional regulator
FOB70_RS10765	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOB70_RS10765	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOB70_RS10770	COG0489	protein tyrosine kinase activity
FOB70_RS10775	COG0572	uridine kinase
FOB70_RS10785	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
FOB70_RS10790	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FOB70_RS10795	COG0659	secondary active sulfate transmembrane transporter activity
FOB70_RS10805	COG1530	ribonuclease E activity
FOB70_RS10820	COG0564	pseudouridine synthase activity
FOB70_RS10825	COG0424	maF-like protein
FOB70_RS10830	COG1399	metal-binding, possibly nucleic acid-binding protein
FOB70_RS10840	COG0416	fatty acid biosynthetic process
FOB70_RS10845	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOB70_RS10875	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FOB70_RS10880	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FOB70_RS10890	COG0084	hydrolase, TatD family'
FOB70_RS10895	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOB70_RS10895	COG1263	PTS System
FOB70_RS10915	COG0733	neurotransmitter:sodium symporter activity
FOB70_RS10930	COG4667	esterase of the alpha-beta hydrolase superfamily
FOB70_RS10935	COG0469	pyruvate kinase activity
FOB70_RS10940	COG1940	carbohydrate kinase activity
FOB70_RS10945	COG0835	chemotaxis
FOB70_RS10945	COG0784	Response regulator, receiver
FOB70_RS10950	COG0587	DNA-directed DNA polymerase activity
FOB70_RS10965	COG1028	Short-chain dehydrogenase reductase Sdr
FOB70_RS10970	COG0616	signal peptide processing
FOB70_RS10975	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FOB70_RS10980	COG0539	negative regulation of cytoplasmic translation
FOB70_RS10990	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
FOB70_RS10995	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
FOB70_RS11000	COG0284	orotidine-5'-phosphate decarboxylase activity
FOB70_RS11005	COG4166	transmembrane transport
FOB70_RS11020	COG0463	Glycosyl transferase, family 2
FOB70_RS11030	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FOB70_RS11040	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FOB70_RS11040	COG3008	intermembrane lipid transfer
FOB70_RS11045	COG2995	paraquat-inducible protein a
FOB70_RS11050	COG3258	Cytochrome c
FOB70_RS11055	COG2863	cytochrome
FOB70_RS11095	COG4232	protein-disulfide reductase activity
FOB70_RS11100	COG3118	belongs to the thioredoxin family
FOB70_RS11130	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOB70_RS11140	COG1136	(ABC) transporter
FOB70_RS11140	COG0577	efflux transmembrane transporter activity
FOB70_RS11145	COG1136	(ABC) transporter
FOB70_RS11145	COG0577	efflux transmembrane transporter activity
FOB70_RS11150	COG1136	(ABC) transporter
FOB70_RS11150	COG0577	efflux transmembrane transporter activity
FOB70_RS11155	COG1335	isochorismatase
FOB70_RS11170	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FOB70_RS11205	COG3850	Histidine kinase
FOB70_RS11205	COG5002	protein histidine kinase activity
FOB70_RS11210	COG0745	RESPONSE REGULATOR receiver
FOB70_RS11220	COG0840	transmembrane signaling receptor activity
FOB70_RS11225	COG1032	radical SAM domain protein
FOB70_RS11230	COG2203	Gaf domain
FOB70_RS11230	COG3706	GGDEF domain
FOB70_RS11230	COG4251	negative regulation of phosphorylation
FOB70_RS11230	COG5001	Diguanylate cyclase
FOB70_RS11245	COG0583	DNA-binding transcription factor activity
FOB70_RS11255	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FOB70_RS11265	COG2350	Protein conserved in bacteria
FOB70_RS11275	COG2917	probably involved in intracellular septation
FOB70_RS11295	COG1301	dicarboxylic acid transport
FOB70_RS11305	COG0318	PFAM AMP-dependent synthetase and ligase
FOB70_RS11310	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FOB70_RS11315	COG0159	tryptophan synthase activity
FOB70_RS11320	COG0133	tryptophan synthase activity
FOB70_RS11325	COG0135	phosphoribosylanthranilate isomerase activity
FOB70_RS11325	COG0134	indole-3-glycerol-phosphate synthase activity
FOB70_RS11330	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FOB70_RS11335	COG0512	Glutamine amidotransferase of anthranilate synthase
FOB70_RS11340	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FOB70_RS11350	COG0613	PHP domain protein
FOB70_RS11355	COG0009	L-threonylcarbamoyladenylate synthase
FOB70_RS11365	COG1187	pseudouridine synthase activity
FOB70_RS11375	COG3099	Belongs to the UPF0263 family
FOB70_RS11380	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FOB70_RS11390	COG0417	DNA replication proofreading
FOB70_RS11395	COG2197	response regulator
FOB70_RS11400	COG0322	excinuclease ABC activity
FOB70_RS11440	COG0019	diaminopimelate decarboxylase activity
FOB70_RS11465	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FOB70_RS11470	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FOB70_RS11475	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FOB70_RS11495	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
FOB70_RS11505	COG0437	4 iron, 4 sulfur cluster binding
FOB70_RS11510	COG3301	Polysulphide reductase, NrfD
FOB70_RS11515	COG1138	Cytochrome C-type biogenesis protein
FOB70_RS11525	COG3088	subunit of a heme lyase
FOB70_RS11525	COG4235	cytochrome complex assembly
FOB70_RS11535	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FOB70_RS11560	COG2989	Protein conserved in bacteria
FOB70_RS11565	COG3108	Peptidase M15
FOB70_RS11570	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOB70_RS11585	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FOB70_RS11610	COG1846	Transcriptional regulator
FOB70_RS11615	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FOB70_RS11620	COG0840	transmembrane signaling receptor activity
FOB70_RS11640	COG1448	Aminotransferase
FOB70_RS11665	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOB70_RS11675	COG0017	Asparaginyl-tRNA synthetase
FOB70_RS11685	COG0720	synthase
FOB70_RS11695	COG2200	EAL domain
FOB70_RS11700	COG1760	l-serine dehydratase
FOB70_RS11705	COG0814	amino acid
FOB70_RS11710	COG0494	nUDIX hydrolase
FOB70_RS11720	COG2205	protein histidine kinase activity
FOB70_RS11720	COG0784	Response regulator, receiver
FOB70_RS11725	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FOB70_RS11745	COG3106	COG3106 Predicted ATPase
FOB70_RS11750	COG3768	UPF0283 membrane protein
FOB70_RS11760	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOB70_RS11905	COG0346	lactoylglutathione lyase activity
FOB70_RS12000	COG2026	Addiction module toxin, RelE StbE family
FOB70_RS12045	COG1051	belongs to the nudix hydrolase family
FOB70_RS12290	COG0456	acetyltransferase
FOB70_RS12305	COG0346	lactoylglutathione lyase activity
FOB70_RS12725	COG1757	Na H antiporter
FOB70_RS12730	COG0174	glutamine synthetase
FOB70_RS12740	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FOB70_RS12745	COG1396	sequence-specific DNA binding
FOB70_RS12745	COG1917	Cupin 2, conserved barrel domain protein
FOB70_RS12750	COG1012	belongs to the aldehyde dehydrogenase family
FOB70_RS12755	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOB70_RS12765	COG2957	Belongs to the agmatine deiminase family
FOB70_RS12770	COG1012	belongs to the aldehyde dehydrogenase family
FOB70_RS12775	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FOB70_RS12780	COG1227	inorganic diphosphatase activity
FOB70_RS12790	COG2771	luxR family
FOB70_RS12790	COG2200	EAL domain
FOB70_RS12805	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FOB70_RS12820	COG1846	Transcriptional regulator
FOB70_RS12825	COG2315	Protein conserved in bacteria
FOB70_RS12845	COG0110	maltose O-acetyltransferase activity
FOB70_RS12875	COG3063	Type IV pilus biogenesis stability protein PilW
FOB70_RS12880	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FOB70_RS12895	COG0531	amino acid
FOB70_RS12905	COG1560	Kdo2-lipid A biosynthetic process
FOB70_RS12910	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
FOB70_RS12915	COG1280	lysine exporter protein (LysE YggA)
FOB70_RS12925	COG1115	amino acid carrier protein
FOB70_RS12950	COG1368	sulfuric ester hydrolase activity
FOB70_RS12955	COG0642	Histidine kinase
FOB70_RS12960	COG0745	RESPONSE REGULATOR receiver
FOB70_RS12970	COG1028	Short-chain dehydrogenase reductase Sdr
FOB70_RS12980	COG1022	Amp-dependent synthetase and ligase
FOB70_RS12990	COG2113	Glycine betaine
FOB70_RS12995	COG4176	ABC-type proline glycine betaine transport system permease component
FOB70_RS13015	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FOB70_RS13020	COG0456	acetyltransferase
FOB70_RS13025	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FOB70_RS13030	COG0662	Cupin 2, conserved barrel domain protein
FOB70_RS13035	COG0527	aspartate kinase activity
FOB70_RS13040	COG1858	cytochrome C peroxidase
FOB70_RS13055	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOB70_RS13070	COG3290	protein histidine kinase activity
FOB70_RS13075	COG4565	transcriptional regulatory protein
FOB70_RS13080	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FOB70_RS13085	COG0363	glucosamine-6-phosphate deaminase activity
FOB70_RS13090	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FOB70_RS13115	COG3284	Transcriptional regulator
FOB70_RS13120	COG1012	belongs to the aldehyde dehydrogenase family
FOB70_RS13190	COG4669	(LipO)protein
FOB70_RS13210	COG3177	Filamentation induced by cAMP protein fic
FOB70_RS13260	COG4792	protein secretion
FOB70_RS13265	COG4791	protein targeting
FOB70_RS13270	COG4794	Type iii secretion
FOB70_RS13275	COG4790	Type iii secretion
FOB70_RS13345	COG0457	Tetratricopeptide repeat
FOB70_RS13365	COG0730	response to heat
FOB70_RS13395	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FOB70_RS13400	COG0372	Belongs to the citrate synthase family
FOB70_RS13410	COG2828	Protein conserved in bacteria
FOB70_RS13435	COG0561	phosphatase activity
FOB70_RS13440	COG0602	queuosine metabolic process
FOB70_RS13445	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FOB70_RS13450	COG3706	GGDEF domain
FOB70_RS13490	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FOB70_RS13495	COG0840	transmembrane signaling receptor activity
FOB70_RS13500	COG1254	Belongs to the acylphosphatase family
FOB70_RS13505	COG2920	part of a sulfur-relay system
FOB70_RS13515	COG0670	Belongs to the BI1 family
FOB70_RS13520	COG1126	abc transporter atp-binding protein
FOB70_RS13525	COG0765	amino acid transport
FOB70_RS13530	COG4597	amino acid ABC transporter
FOB70_RS13535	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOB70_RS13555	COG1666	GTP binding
FOB70_RS13560	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FOB70_RS13580	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
FOB70_RS13580	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FOB70_RS13590	COG3008	intermembrane lipid transfer
FOB70_RS13595	COG2995	paraquat-inducible protein a
FOB70_RS13600	COG1132	(ABC) transporter
FOB70_RS13605	COG1956	GAF domain-containing protein
FOB70_RS13610	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
FOB70_RS13625	COG0308	aminopeptidase N
FOB70_RS13635	COG2902	Dehydrogenase
FOB70_RS13640	COG0167	dihydroorotate dehydrogenase activity
FOB70_RS13655	COG0116	Belongs to the methyltransferase superfamily
FOB70_RS13655	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FOB70_RS13665	COG0488	(ABC) transporter
FOB70_RS13680	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FOB70_RS13685	COG1067	ATP-dependent peptidase activity
FOB70_RS13690	COG3120	sequence-specific DNA binding
FOB70_RS13790	COG2205	protein histidine kinase activity
FOB70_RS13790	COG0784	Response regulator, receiver
FOB70_RS13805	COG3278	Belongs to the heme-copper respiratory oxidase family
FOB70_RS13820	COG2010	Cytochrome c
FOB70_RS13830	COG2217	Heavy metal translocating P-type atpase
FOB70_RS13845	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FOB70_RS13850	COG0589	response to stress
FOB70_RS13860	COG0037	tRNA processing
FOB70_RS13880	COG3842	ATPase activity
FOB70_RS13890	COG1177	transmembrane transport
FOB70_RS13900	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FOB70_RS13905	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FOB70_RS13915	COG0004	ammonium transporteR
FOB70_RS13955	COG0437	4 iron, 4 sulfur cluster binding
FOB70_RS13960	COG0243	molybdopterin cofactor binding
FOB70_RS13960	COG3383	formate dehydrogenase (NAD+) activity
FOB70_RS13970	COG3381	protein complex oligomerization
FOB70_RS13995	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FOB70_RS14000	COG0488	(ABC) transporter
FOB70_RS14010	COG4191	Histidine kinase
FOB70_RS14015	COG2204	response regulator
FOB70_RS14035	COG3842	ATPase activity
FOB70_RS14040	COG0746	molybdenum cofactor guanylyltransferase activity
FOB70_RS14045	COG0303	'Molybdopterin
FOB70_RS14055	COG1940	carbohydrate kinase activity
FOB70_RS14060	COG3148	PFAM DTW domain containing protein
FOB70_RS14095	COG3290	protein histidine kinase activity
FOB70_RS14095	COG0840	transmembrane signaling receptor activity
FOB70_RS14100	COG0791	NLP P60 protein
FOB70_RS14110	COG3706	GGDEF domain
FOB70_RS14115	COG2201	protein-glutamate methylesterase activity
FOB70_RS14120	COG3001	Fructosamine kinase
FOB70_RS14130	COG0307	riboflavin synthase, alpha
FOB70_RS14135	COG0534	Mate efflux family protein
FOB70_RS14145	COG1793	dna ligase
FOB70_RS14180	COG2204	response regulator
FOB70_RS14190	COG0438	transferase activity, transferring glycosyl groups
FOB70_RS14225	COG0438	transferase activity, transferring glycosyl groups
FOB70_RS14230	COG1215	transferase activity, transferring glycosyl groups
FOB70_RS14235	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FOB70_RS14245	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FOB70_RS14260	COG1643	Atp-dependent helicase
FOB70_RS14265	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FOB70_RS14280	COG3302	dmso reductase anchor subunit
FOB70_RS14285	COG0437	4 iron, 4 sulfur cluster binding
FOB70_RS14290	COG0243	molybdopterin cofactor binding
FOB70_RS14330	COG0443	Heat shock 70 kDa protein
FOB70_RS14335	COG0443	Heat shock 70 kDa protein
FOB70_RS14365	COG1132	(ABC) transporter
FOB70_RS14370	COG1132	(ABC) transporter
FOB70_RS14395	COG0814	amino acid
FOB70_RS14410	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FOB70_RS14480	COG1522	sequence-specific DNA binding
FOB70_RS14515	COG0515	serine threonine protein kinase
FOB70_RS14540	COG3501	Rhs element vgr protein
FOB70_RS14560	COG2885	chlorophyll binding
FOB70_RS14580	COG0739	heme binding
FOB70_RS14590	COG0861	Integral membrane protein TerC family
FOB70_RS14600	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FOB70_RS14605	COG1328	CTP reductase activity
FOB70_RS14610	COG1280	lysine exporter protein (LysE YggA)
FOB70_RS14620	COG5001	Diguanylate cyclase
FOB70_RS14620	COG3300	MHYT domain
FOB70_RS14630	COG4191	Histidine kinase
FOB70_RS14630	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOB70_RS14635	COG0471	metal ion transport
FOB70_RS14670	COG0583	DNA-binding transcription factor activity
FOB70_RS14675	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
FOB70_RS14905	COG1783	phage Terminase large subunit
FOB70_RS14950	COG0557	exoribonuclease II activity
FOB70_RS14955	COG1278	Cold shock
FOB70_RS15070	COG0625	glutathione transferase activity
FOB70_RS15080	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
FOB70_RS15095	COG2195	Cleaves the N-terminal amino acid of tripeptides
FOB70_RS15105	COG0601	transmembrane transport
FOB70_RS15110	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOB70_RS15115	COG0444	Belongs to the ABC transporter superfamily
FOB70_RS15135	COG3291	Pkd domain containing protein
FOB70_RS15150	COG1177	transmembrane transport
FOB70_RS15155	COG1176	ABC-type spermidine putrescine transport system, permease component I
FOB70_RS15165	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FOB70_RS15170	COG2423	ornithine cyclodeaminase activity
FOB70_RS15190	COG3938	Belongs to the proline racemase family
FOB70_RS15220	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
FOB70_RS15225	COG1451	nucleotide metabolic process
FOB70_RS15230	COG3475	LICD family
FOB70_RS15235	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOB70_RS15240	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FOB70_RS15260	COG0583	DNA-binding transcription factor activity
FOB70_RS15280	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
FOB70_RS15285	COG4139	cobalamin transport
FOB70_RS15290	COG2988	succinylglutamate desuccinylase activity
FOB70_RS15315	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FOB70_RS15320	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FOB70_RS15325	COG0702	epimerase
FOB70_RS15330	COG1823	symporter activity
FOB70_RS15335	COG2925	Exonuclease
FOB70_RS15340	COG1380	Effector of murein hydrolase LrgA
FOB70_RS15345	COG1346	cytolysis
FOB70_RS15350	COG0295	cytidine deaminase activity
FOB70_RS15355	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
FOB70_RS15360	COG0500	methyltransferase
FOB70_RS15370	COG0776	regulation of translation
FOB70_RS15385	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOB70_RS15385	COG0072	phenylalanine-tRNA ligase activity
FOB70_RS15390	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FOB70_RS15395	COG3706	GGDEF domain
FOB70_RS15425	COG0393	Putative heavy-metal-binding
FOB70_RS15435	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FOB70_RS15445	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FOB70_RS15460	COG2188	Transcriptional regulator
FOB70_RS15465	COG1228	amidohydrolase
FOB70_RS15470	COG0010	Belongs to the arginase family
FOB70_RS15475	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FOB70_RS15480	COG2986	histidine ammonia-lyase
FOB70_RS15495	COG0247	lactate metabolic process
FOB70_RS15495	COG0277	FAD linked oxidase domain protein
FOB70_RS15530	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FOB70_RS15545	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
FOB70_RS15550	COG1643	Atp-dependent helicase
FOB70_RS15555	COG0281	malic enzyme
FOB70_RS15560	COG2949	membrane
FOB70_RS15565	COG0471	metal ion transport
FOB70_RS15590	COG0492	ferredoxin-NADP+ reductase activity
FOB70_RS15595	COG4988	ABC transporter
FOB70_RS15600	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FOB70_RS15605	COG3048	D-serine ammonia-lyase activity
FOB70_RS15610	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FOB70_RS15620	COG4191	Histidine kinase
FOB70_RS15620	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOB70_RS15635	COG3070	regulator of competence-specific genes
FOB70_RS15655	COG2431	L-lysine efflux transmembrane transporter activity
FOB70_RS15665	COG0076	glutamate decarboxylase activity
FOB70_RS15670	COG1737	Transcriptional regulator
FOB70_RS15685	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FOB70_RS15690	COG3273	potassium ion transport
FOB70_RS15690	COG2985	domain, Protein
FOB70_RS15695	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FOB70_RS15710	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FOB70_RS15725	COG4181	ATPase activity
FOB70_RS15730	COG0534	Mate efflux family protein
FOB70_RS15735	COG0702	epimerase
FOB70_RS15740	COG3005	denitrification pathway
FOB70_RS15770	COG2814	Major facilitator Superfamily
FOB70_RS15775	COG1187	pseudouridine synthase activity
FOB70_RS15780	COG1061	Type III restriction enzyme res subunit
FOB70_RS15800	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FOB70_RS15830	COG3313	Fe-S protein
FOB70_RS15855	COG0493	'glutamate synthase
FOB70_RS15865	COG0398	Pfam SNARE associated Golgi protein
FOB70_RS15870	COG4134	Bacterial extracellular solute-binding protein
FOB70_RS15875	COG4135	transport system, permease component
FOB70_RS15880	COG4136	ATPase activity
FOB70_RS15885	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FOB70_RS15900	COG3604	Transcriptional regulator
FOB70_RS15905	COG1151	hydroxylamine reductase activity
FOB70_RS15910	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FOB70_RS15920	COG0564	pseudouridine synthase activity
FOB70_RS15930	COG0733	neurotransmitter:sodium symporter activity
FOB70_RS15940	COG0626	cystathionine gamma-synthase activity
FOB70_RS15945	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
FOB70_RS15950	COG5380	lipid catabolic process
FOB70_RS15955	COG2818	Glycosylase
FOB70_RS15970	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOB70_RS15975	COG1983	PspC domain protein
FOB70_RS15985	COG1842	Phage shock protein A
FOB70_RS15990	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
FOB70_RS16005	COG4171	peptide transport system, permease
FOB70_RS16015	COG4172	Belongs to the ABC transporter superfamily
FOB70_RS16025	COG1227	inorganic diphosphatase activity
FOB70_RS16040	COG0243	molybdopterin cofactor binding
FOB70_RS16045	COG3005	denitrification pathway
FOB70_RS16050	COG4459	periplasmic nitrate reductase
FOB70_RS16055	COG0390	transport system, permease component
FOB70_RS16065	COG2116	formate transmembrane transporter activity
FOB70_RS16090	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FOB70_RS16095	COG1435	thymidine kinase activity
FOB70_RS16100	COG0215	cysteine-tRNA ligase activity
FOB70_RS16105	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FOB70_RS16110	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FOB70_RS16115	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FOB70_RS16125	COG3012	SEC-C Motif Domain Protein
FOB70_RS16130	COG0140	phosphoribosyl-ATP diphosphatase activity
FOB70_RS16130	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FOB70_RS16135	COG0107	imidazoleglycerol-phosphate synthase activity
FOB70_RS16140	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FOB70_RS16145	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FOB70_RS16150	COG0131	Imidazoleglycerol-phosphate dehydratase
FOB70_RS16150	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FOB70_RS16155	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FOB70_RS16160	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FOB70_RS16165	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FOB70_RS16180	COG1757	Na H antiporter
FOB70_RS16190	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOB70_RS16200	COG0482	sulfurtransferase activity
FOB70_RS16205	COG2915	High frequency lysogenization protein hflD homolog
FOB70_RS16210	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FOB70_RS16235	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FOB70_RS16250	COG0300	oxidoreductase activity
FOB70_RS16260	COG0501	Belongs to the peptidase M48B family
FOB70_RS16270	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FOB70_RS16280	COG0156	8-amino-7-oxononanoate synthase activity
FOB70_RS16285	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FOB70_RS16290	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FOB70_RS16295	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FOB70_RS16310	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FOB70_RS16315	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FOB70_RS16320	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FOB70_RS16325	COG1674	ftsk spoiiie
FOB70_RS16335	COG0686	Belongs to the AlaDH PNT family
FOB70_RS16345	COG0583	DNA-binding transcription factor activity
FOB70_RS16360	COG3568	Endonuclease Exonuclease Phosphatase
FOB70_RS16390	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOB70_RS16395	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOB70_RS16410	COG0840	transmembrane signaling receptor activity
FOB70_RS16425	COG5002	protein histidine kinase activity
FOB70_RS16425	COG0784	Response regulator, receiver
FOB70_RS16435	COG0754	glutathionylspermidine amidase activity
FOB70_RS16445	COG3766	membrane
FOB70_RS16455	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FOB70_RS16460	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
FOB70_RS16465	COG2885	chlorophyll binding
FOB70_RS16470	COG0823	Involved in the tonB-independent uptake of proteins
FOB70_RS16485	COG0811	peptide transport
FOB70_RS16490	COG0824	Thioesterase
FOB70_RS16500	COG4890	Cyd operon protein YbgT
FOB70_RS16505	COG1294	oxidase, subunit
FOB70_RS16510	COG1271	oxidase subunit
FOB70_RS16515	COG2255	four-way junction helicase activity
FOB70_RS16520	COG0632	four-way junction helicase activity
FOB70_RS16525	COG0840	transmembrane signaling receptor activity
FOB70_RS16530	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FOB70_RS16535	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FOB70_RS16540	COG1801	Protein of unknown function DUF72
FOB70_RS16545	COG4106	trans-aconitate 2-methyltransferase activity
FOB70_RS16550	COG0500	methyltransferase
FOB70_RS16560	COG4067	protein conserved in archaea
FOB70_RS16560	COG0189	ligase activity
FOB70_RS16580	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FOB70_RS16585	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
FOB70_RS16590	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
FOB70_RS16595	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FOB70_RS16600	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FOB70_RS16605	COG0745	RESPONSE REGULATOR receiver
FOB70_RS16610	COG3381	protein complex oligomerization
FOB70_RS16615	COG1609	Transcriptional regulator
FOB70_RS16620	COG3070	regulator of competence-specific genes
FOB70_RS16640	COG0297	glycogen (starch) synthase activity
FOB70_RS16645	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FOB70_RS16650	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FOB70_RS16660	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FOB70_RS16670	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FOB70_RS16675	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FOB70_RS16680	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FOB70_RS16690	COG0542	response to heat
FOB70_RS16695	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FOB70_RS16700	COG1278	Cold shock
FOB70_RS16710	COG1187	pseudouridine synthase activity
FOB70_RS16715	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
FOB70_RS16725	COG1199	ATP-dependent helicase activity
FOB70_RS16730	COG0730	response to heat
FOB70_RS16735	COG3923	Primosomal replication protein n
FOB70_RS16745	COG0708	Exodeoxyribonuclease III
FOB70_RS16790	COG1882	Formate acetyltransferase
FOB70_RS16800	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FOB70_RS16810	COG3013	Belongs to the UPF0304 family
FOB70_RS16820	COG2766	serine protein kinase
FOB70_RS16825	COG2718	Belongs to the UPF0229 family
FOB70_RS16830	COG2719	SpoVR family
FOB70_RS16835	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FOB70_RS16845	COG1663	tetraacyldisaccharide 4'-kinase activity
FOB70_RS16850	COG1132	(ABC) transporter
FOB70_RS16855	COG2333	competence protein COMEC
FOB70_RS16855	COG0658	competence protein
FOB70_RS16865	COG4591	ABC-type transport system involved in lipoprotein release permease component
FOB70_RS16870	COG1136	(ABC) transporter
FOB70_RS16875	COG4591	ABC-type transport system involved in lipoprotein release permease component
FOB70_RS16885	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FOB70_RS16900	COG1252	NADH dehydrogenase
FOB70_RS16910	COG3150	esterase
FOB70_RS16935	COG0537	adenosine 5'-monophosphoramidase activity
FOB70_RS16965	COG0516	GMP reductase activity
FOB70_RS16965	COG0517	IMP dehydrogenase activity
FOB70_RS16975	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
FOB70_RS16980	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FOB70_RS16985	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FOB70_RS16995	COG2199	diguanylate cyclase activity
FOB70_RS17010	COG3126	Type III secretion system lipoprotein chaperone (YscW)
FOB70_RS17015	COG1946	Acyl-CoA thioesterase
FOB70_RS17025	COG1522	sequence-specific DNA binding
FOB70_RS17055	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOB70_RS17105	COG0477	Major facilitator Superfamily
FOB70_RS17110	COG2855	membrane
FOB70_RS17135	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FOB70_RS17140	COG0596	Alpha beta hydrolase
FOB70_RS17145	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
FOB70_RS17150	COG1169	isochorismate synthase
FOB70_RS17155	COG0436	Aminotransferase
FOB70_RS17160	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
FOB70_RS17165	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FOB70_RS17180	COG1555	photosystem II stabilization
FOB70_RS17185	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FOB70_RS17190	COG0776	regulation of translation
FOB70_RS17195	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FOB70_RS17200	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FOB70_RS17210	COG0544	peptidyl-prolyl cis-trans isomerase activity
FOB70_RS17220	COG2204	response regulator
FOB70_RS17230	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FOB70_RS17235	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FOB70_RS17240	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FOB70_RS17245	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FOB70_RS17265	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FOB70_RS17270	COG0569	domain protein
FOB70_RS17275	COG0513	Belongs to the DEAD box helicase family
FOB70_RS17280	COG1253	flavin adenine dinucleotide binding
FOB70_RS17310	COG0318	PFAM AMP-dependent synthetase and ligase
FOB70_RS17310	COG0204	Acyl-transferase
FOB70_RS17315	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FOB70_RS17320	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FOB70_RS17335	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FOB70_RS17340	COG1216	Glycosyl transferase, family 2
FOB70_RS17345	COG2986	histidine ammonia-lyase
FOB70_RS17370	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FOB70_RS17380	COG1028	Short-chain dehydrogenase reductase Sdr
FOB70_RS17385	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FOB70_RS17400	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FOB70_RS17405	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOB70_RS17410	COG0583	DNA-binding transcription factor activity
FOB70_RS17415	COG2951	lytic endotransglycosylase activity
FOB70_RS17420	COG3100	YcgL domain-containing protein
FOB70_RS17425	COG0850	regulation of cytokinetic process
FOB70_RS17430	COG2894	cell division
FOB70_RS17435	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FOB70_RS17440	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FOB70_RS17445	COG0318	PFAM AMP-dependent synthetase and ligase
FOB70_RS17450	COG2267	carboxylic ester hydrolase activity
FOB70_RS17465	COG1214	PFAM Peptidase M22, glycoprotease
FOB70_RS17470	COG1199	ATP-dependent helicase activity
FOB70_RS17475	COG0788	formyltetrahydrofolate deformylase activity
FOB70_RS17480	COG3102	Protein conserved in bacteria
FOB70_RS17490	COG0018	arginyl-trna synthetase
FOB70_RS17510	COG1918	ferrous iron import across plasma membrane
FOB70_RS17525	COG4977	sequence-specific DNA binding
FOB70_RS17530	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
FOB70_RS17535	COG1121	(ABC) transporter
FOB70_RS17540	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FOB70_RS17550	COG0045	succinate-CoA ligase (ADP-forming) activity
FOB70_RS17555	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOB70_RS17560	COG0567	Dehydrogenase, E1 component
FOB70_RS17565	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FOB70_RS17570	COG1053	succinate dehydrogenase
FOB70_RS17575	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FOB70_RS17590	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FOB70_RS17600	COG0033	Phosphoglucomutase
FOB70_RS17605	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
FOB70_RS17610	COG0596	Alpha beta hydrolase
FOB70_RS17630	COG0735	belongs to the Fur family
FOB70_RS17635	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FOB70_RS17640	COG2190	(PTS) system
FOB70_RS17640	COG1263	PTS System
FOB70_RS17640	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOB70_RS17650	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FOB70_RS17655	COG1940	carbohydrate kinase activity
FOB70_RS17655	COG1846	Transcriptional regulator
FOB70_RS17660	COG4651	solute:proton antiporter activity
FOB70_RS17660	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FOB70_RS17665	COG0367	asparagine synthase
FOB70_RS17670	COG0250	Participates in transcription elongation, termination and antitermination
FOB70_RS17675	COG3104	oligopeptide transport
FOB70_RS17680	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FOB70_RS17685	COG0563	adenylate kinase activity
FOB70_RS17690	COG0326	Molecular chaperone. Has ATPase activity
FOB70_RS17695	COG3710	Transcriptional regulator
FOB70_RS17715	COG0622	Phosphoesterase
FOB70_RS17745	COG1090	epimerase
FOB70_RS17750	COG0300	oxidoreductase activity
FOB70_RS17760	COG3118	belongs to the thioredoxin family
FOB70_RS17765	COG0330	HflC and HflK could
FOB70_RS17790	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FOB70_RS17795	COG3115	cell septum assembly
FOB70_RS17800	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
FOB70_RS17805	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FOB70_RS17815	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOB70_RS17820	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FOB70_RS17825	COG2190	(PTS) system
FOB70_RS17835	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FOB70_RS17840	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FOB70_RS17850	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FOB70_RS17860	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FOB70_RS17870	COG1705	Flagellar rod assembly protein muramidase FlgJ
FOB70_RS17870	COG3951	Flagellar rod assembly protein muramidase FlgJ
FOB70_RS17875	COG1706	bacterial-type flagellum-dependent cell motility
FOB70_RS17880	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FOB70_RS17890	COG4787	bacterial-type flagellum-dependent cell motility
FOB70_RS17900	COG1749	Flagellar hook protein flgE
FOB70_RS17910	COG1558	bacterial-type flagellum-dependent cell motility
FOB70_RS17915	COG1815	bacterial-type flagellum-dependent cell motility
FOB70_RS17920	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FOB70_RS17925	COG0784	Response regulator, receiver
FOB70_RS17925	COG0835	chemotaxis
FOB70_RS17985	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FOB70_RS17990	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
FOB70_RS18005	COG2608	mercury ion transmembrane transporter activity
FOB70_RS18005	COG2217	Heavy metal translocating P-type atpase
FOB70_RS18045	COG2840	Smr protein MutS2
FOB70_RS18050	COG1187	pseudouridine synthase activity
FOB70_RS18060	COG0737	Belongs to the 5'-nucleotidase family
FOB70_RS18065	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FOB70_RS18070	COG2912	Transglutaminase-like superfamily
FOB70_RS18075	COG3094	Invasion gene expression up-regulator, SirB
FOB70_RS18080	COG2890	protein-(glutamine-N5) methyltransferase activity
FOB70_RS18085	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FOB70_RS18090	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FOB70_RS18105	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FOB70_RS18110	COG0193	aminoacyl-tRNA hydrolase activity
FOB70_RS18115	COG0012	GTP binding
FOB70_RS18230	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FOB70_RS18240	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FOB70_RS18245	COG1702	phosphate starvation-inducible protein PhoH
FOB70_RS18250	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FOB70_RS18255	COG4535	Mg2 and Co2 transporter CorC
FOB70_RS18260	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FOB70_RS18265	COG2888	peptidyl-tyrosine sulfation
FOB70_RS18270	COG0495	leucyl-tRNA aminoacylation
FOB70_RS18275	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
FOB70_RS18280	COG1466	dna polymerase III delta subunit
FOB70_RS18285	COG0799	negative regulation of ribosome biogenesis
FOB70_RS18290	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FOB70_RS18295	COG0768	penicillin binding
FOB70_RS18300	COG0772	Belongs to the SEDS family
FOB70_RS18305	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FOB70_RS18310	COG1686	Belongs to the peptidase S11 family
FOB70_RS18315	COG2921	Belongs to the UPF0250 family
FOB70_RS18320	COG0321	lipoyl(octanoyl) transferase activity
FOB70_RS18325	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FOB70_RS18330	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FOB70_RS18335	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOB70_RS18350	COG0366	Alpha amylase catalytic
FOB70_RS18355	COG1263	PTS System
FOB70_RS18355	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOB70_RS18365	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FOB70_RS18375	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FOB70_RS18380	COG2011	ABC-type metal ion transport system permease component
FOB70_RS18385	COG1464	Belongs to the NlpA lipoprotein family
FOB70_RS18390	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
FOB70_RS18400	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FOB70_RS18400	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FOB70_RS18415	COG1611	Belongs to the LOG family
FOB70_RS18420	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOB70_RS18430	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
FOB70_RS18435	COG2363	Small membrane protein
FOB70_RS18445	COG0583	DNA-binding transcription factor activity
FOB70_RS18450	COG0301	tRNA thio-modification
FOB70_RS18450	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOB70_RS18455	COG2885	chlorophyll binding
FOB70_RS18460	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FOB70_RS18465	COG1722	exodeoxyribonuclease VII activity
FOB70_RS18470	COG0142	geranyltranstransferase activity
FOB70_RS18475	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FOB70_RS18480	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FOB70_RS18485	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FOB70_RS18490	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FOB70_RS18510	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FOB70_RS18510	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FOB70_RS18515	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FOB70_RS18520	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FOB70_RS18525	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FOB70_RS18535	COG1073	alpha beta
FOB70_RS18540	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
FOB70_RS18545	COG2252	PERMEase
FOB70_RS18550	COG2195	Cleaves the N-terminal amino acid of tripeptides
FOB70_RS18575	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FOB70_RS18575	COG0047	phosphoribosylformylglycinamidine synthase activity
FOB70_RS18585	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FOB70_RS18600	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
FOB70_RS18625	COG4969	Belongs to the N-Me-Phe pilin family
FOB70_RS18640	COG0484	heat shock protein binding
FOB70_RS18645	COG0443	Heat shock 70 kDa protein
FOB70_RS18650	COG1301	dicarboxylic acid transport
FOB70_RS18655	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FOB70_RS18660	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FOB70_RS18670	COG0497	DNA recombination
FOB70_RS18675	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FOB70_RS18680	COG2914	Belongs to the UPF0125 (RnfH) family
FOB70_RS18685	COG2867	negative regulation of translational initiation
FOB70_RS18690	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FOB70_RS18710	COG0583	DNA-binding transcription factor activity
FOB70_RS18715	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FOB70_RS18715	COG3153	acetyltransferase
FOB70_RS18735	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FOB70_RS18740	COG2873	o-acetylhomoserine
FOB70_RS18780	COG1115	amino acid carrier protein
FOB70_RS18790	COG1584	GPR1 FUN34 yaaH family protein
FOB70_RS18800	COG1757	Na H antiporter
FOB70_RS18805	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FOB70_RS18805	COG0519	Catalyzes the synthesis of GMP from XMP
FOB70_RS18810	COG0517	IMP dehydrogenase activity
FOB70_RS18810	COG0516	GMP reductase activity
FOB70_RS18815	COG1570	exodeoxyribonuclease VII activity
FOB70_RS18830	COG1160	GTP binding
FOB70_RS18835	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FOB70_RS18840	COG2976	Protein conserved in bacteria
FOB70_RS18845	COG0124	histidyl-tRNA synthetase
FOB70_RS18850	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FOB70_RS18865	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FOB70_RS18870	COG0105	UTP biosynthetic process
FOB70_RS18875	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FOB70_RS18880	COG2975	iron-sulfur cluster assembly
FOB70_RS18885	COG0633	Ferredoxin
FOB70_RS18890	COG0443	Heat shock 70 kDa protein
FOB70_RS18895	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FOB70_RS18905	COG0822	iron-sulfur transferase activity
FOB70_RS18910	COG1104	cysteine desulfurase activity
FOB70_RS18915	COG1959	2 iron, 2 sulfur cluster binding
FOB70_RS18925	COG0483	inositol monophosphate 1-phosphatase activity
FOB70_RS18935	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FOB70_RS18940	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FOB70_RS18945	COG1862	Preprotein translocase
FOB70_RS18950	COG0343	queuine tRNA-ribosyltransferase activity
FOB70_RS18955	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FOB70_RS18970	COG0517	IMP dehydrogenase activity
FOB70_RS18980	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FOB70_RS18990	COG0583	DNA-binding transcription factor activity
FOB70_RS18995	COG0450	alkyl hydroperoxide reductase
FOB70_RS19005	COG3142	Participates in the control of copper homeostasis
FOB70_RS19015	COG0704	Plays a role in the regulation of phosphate uptake
FOB70_RS19020	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FOB70_RS19025	COG0581	inorganic phosphate transmembrane transporter activity
FOB70_RS19035	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FOB70_RS19040	COG0248	Ppx GppA phosphatase
FOB70_RS19050	COG5002	protein histidine kinase activity
FOB70_RS19055	COG0745	RESPONSE REGULATOR receiver
FOB70_RS19065	COG2974	May be involved in recombination
FOB70_RS19070	COG0826	peptidase U32
FOB70_RS19075	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FOB70_RS19135	COG0542	response to heat
FOB70_RS19145	COG0564	pseudouridine synthase activity
FOB70_RS19150	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FOB70_RS19155	COG0741	lytic transglycosylase activity
FOB70_RS19160	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FOB70_RS19165	COG0077	Prephenate dehydratase
FOB70_RS19165	COG1605	Chorismate mutase
FOB70_RS19170	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
FOB70_RS19175	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
FOB70_RS19185	COG0488	(ABC) transporter
FOB70_RS19200	COG0739	heme binding
FOB70_RS19205	COG0287	Prephenate dehydrogenase
FOB70_RS19205	COG1605	Chorismate mutase
FOB70_RS19210	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FOB70_RS19215	COG1472	Belongs to the glycosyl hydrolase 3 family
FOB70_RS19220	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FOB70_RS19225	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FOB70_RS19240	COG1966	Carbon starvation protein
FOB70_RS19245	COG3275	phosphorelay sensor kinase activity
FOB70_RS19250	COG3279	Response regulator of the LytR AlgR family
FOB70_RS19255	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FOB70_RS19260	COG1047	Peptidyl-prolyl cis-trans
FOB70_RS19265	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FOB70_RS19270	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FOB70_RS19275	COG0196	riboflavin kinase activity
FOB70_RS19280	COG0728	peptidoglycan biosynthetic process
FOB70_RS19285	COG0268	Binds directly to 16S ribosomal RNA
FOB70_RS19295	COG0640	Transcriptional regulator
FOB70_RS19305	COG0583	DNA-binding transcription factor activity
FOB70_RS19310	COG1283	sodium-dependent phosphate transmembrane transporter activity
FOB70_RS19320	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FOB70_RS19325	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FOB70_RS19330	COG0730	response to heat
FOB70_RS19340	COG0494	nUDIX hydrolase
FOB70_RS19350	COG3066	DNA modification
FOB70_RS19360	COG0667	Aldo Keto reductase
FOB70_RS19375	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FOB70_RS19385	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FOB70_RS19390	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FOB70_RS19395	COG4974	Belongs to the 'phage' integrase family
FOB70_RS19400	COG0716	FMN binding
FOB70_RS19410	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FOB70_RS19415	COG0513	Belongs to the DEAD box helicase family
FOB70_RS19420	COG3022	response to hydroperoxide
FOB70_RS19425	COG1115	amino acid carrier protein
FOB70_RS19440	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FOB70_RS19450	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
FOB70_RS19455	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
FOB70_RS19460	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FOB70_RS19465	COG0083	homoserine kinase activity
FOB70_RS19480	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FOB70_RS19495	COG0745	RESPONSE REGULATOR receiver
FOB70_RS19505	COG2198	Histidine kinase
FOB70_RS19505	COG0784	Response regulator, receiver
FOB70_RS19505	COG5002	protein histidine kinase activity
FOB70_RS19510	COG3706	GGDEF domain
FOB70_RS19510	COG4251	negative regulation of phosphorylation
FOB70_RS19510	COG2203	Gaf domain
FOB70_RS19510	COG5001	Diguanylate cyclase
FOB70_RS19515	COG1242	4 iron, 4 sulfur cluster binding
FOB70_RS19520	COG0070	glutamate synthase
FOB70_RS19520	COG0069	glutamate synthase activity
FOB70_RS19520	COG0067	glutamate synthase
FOB70_RS19530	COG0067	glutamate synthase
FOB70_RS19530	COG0069	glutamate synthase activity
FOB70_RS19530	COG0070	glutamate synthase
FOB70_RS19535	COG0493	'glutamate synthase
FOB70_RS19545	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FOB70_RS19555	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOB70_RS19560	COG2860	membrane
FOB70_RS19565	COG0583	DNA-binding transcription factor activity
FOB70_RS19570	COG0730	response to heat
FOB70_RS19580	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FOB70_RS19585	COG0505	Belongs to the CarA family
FOB70_RS19590	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FOB70_RS19595	COG0494	nUDIX hydrolase
FOB70_RS19600	COG0653	protein targeting
FOB70_RS19610	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
FOB70_RS19615	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FOB70_RS19620	COG0849	cell division
FOB70_RS19625	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FOB70_RS19630	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FOB70_RS19635	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FOB70_RS19640	COG0772	Belongs to the SEDS family
FOB70_RS19645	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FOB70_RS19650	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FOB70_RS19655	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FOB70_RS19660	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FOB70_RS19665	COG0768	penicillin binding
FOB70_RS19670	COG3116	cell division
FOB70_RS19675	COG0275	rRNA processing
FOB70_RS19690	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FOB70_RS19700	COG0792	nuclease activity
FOB70_RS19705	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FOB70_RS19710	COG2823	Periplasmic or secreted lipoprotein
FOB70_RS19715	COG2969	positive regulation of protein catabolic process
FOB70_RS19720	COG0625	glutathione transferase activity
FOB70_RS19725	COG2857	Cytochrome c1
FOB70_RS19730	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FOB70_RS19735	COG0723	plastoquinol--plastocyanin reductase activity
FOB70_RS19740	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FOB70_RS19745	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FOB70_RS19755	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FOB70_RS19765	COG3105	Protein conserved in bacteria
FOB70_RS19775	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOB70_RS19780	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FOB70_RS19790	COG3150	esterase
FOB70_RS19800	COG3151	Protein conserved in bacteria
FOB70_RS19805	COG0494	nUDIX hydrolase
FOB70_RS19810	COG1538	Outer membrane efflux protein
FOB70_RS19815	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FOB70_RS19815	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FOB70_RS19820	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FOB70_RS19835	COG3025	triphosphatase activity
FOB70_RS19840	COG1392	Phosphate transport regulator
FOB70_RS19845	COG0306	phosphate transporter
FOB70_RS19850	COG4991	sh3 domain protein
FOB70_RS19860	COG3409	Peptidoglycan-binding domain 1 protein
FOB70_RS19860	COG3267	Type II secretory pathway component ExeA
FOB70_RS19865	COG0617	tRNA 3'-terminal CCA addition
FOB70_RS19870	COG1968	undecaprenyl-diphosphatase activity
FOB70_RS19875	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FOB70_RS19880	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FOB70_RS19885	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FOB70_RS19890	COG0596	Alpha beta hydrolase
FOB70_RS19895	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FOB70_RS19900	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FOB70_RS19905	COG1610	YqeY-like protein
FOB70_RS19910	COG0358	DNA primase activity
FOB70_RS19925	COG1464	Belongs to the NlpA lipoprotein family
FOB70_RS19935	COG2207	Transcriptional regulator
FOB70_RS19970	COG2213	PTS system mannitol-specific
FOB70_RS19970	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOB70_RS19975	COG0246	Mannitol dehydrogenase
FOB70_RS19980	COG3722	fumarate hydratase activity
FOB70_RS19995	COG1461	Dihydroxyacetone kinase
FOB70_RS20000	COG2376	Dihydroxyacetone kinase
FOB70_RS20010	COG5002	protein histidine kinase activity
FOB70_RS20025	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FOB70_RS20030	COG1349	DNA-binding transcription factor activity
FOB70_RS20040	COG0469	pyruvate kinase activity
FOB70_RS20055	COG0440	acetolactate synthase activity
FOB70_RS20060	COG0028	Belongs to the TPP enzyme family
FOB70_RS20065	COG1022	Amp-dependent synthetase and ligase
FOB70_RS20070	COG0583	DNA-binding transcription factor activity
FOB70_RS20090	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FOB70_RS20095	COG0473	3-isopropylmalate dehydrogenase activity
FOB70_RS20100	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FOB70_RS20105	COG0066	3-isopropylmalate dehydratase activity
FOB70_RS20115	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FOB70_RS20120	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FOB70_RS20125	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FOB70_RS20130	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FOB70_RS20135	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FOB70_RS20140	COG2967	ApaG domain
FOB70_RS20145	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FOB70_RS20160	COG2966	Psort location CytoplasmicMembrane, score
FOB70_RS20165	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FOB70_RS20175	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FOB70_RS20180	COG0142	geranyltranstransferase activity
FOB70_RS20190	COG0039	L-malate dehydrogenase activity
FOB70_RS20205	COG2358	TRAP transporter, solute receptor (TAXI family
FOB70_RS20225	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FOB70_RS20230	COG1178	ABC-type Fe3 transport system permease component
FOB70_RS20235	COG4143	(ABC) transporter
FOB70_RS20240	COG0163	prenyltransferase activity
FOB70_RS20245	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FOB70_RS20255	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
FOB70_RS20260	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FOB70_RS20270	COG2105	PFAM AIG2 family protein
FOB70_RS20275	COG2911	Protein conserved in bacteria
FOB70_RS20280	COG0729	surface antigen
FOB70_RS20285	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FOB70_RS20295	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
FOB70_RS20310	COG4181	ATPase activity
FOB70_RS20330	COG0529	Catalyzes the synthesis of activated sulfate
FOB70_RS20335	COG3273	potassium ion transport
FOB70_RS20335	COG0471	metal ion transport
FOB70_RS20345	COG2895	sulfate adenylyltransferase (ATP) activity
FOB70_RS20350	COG0175	sulfate reduction
FOB70_RS20355	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FOB70_RS20355	COG1648	precorrin-2 dehydrogenase activity
FOB70_RS20360	COG0737	Belongs to the 5'-nucleotidase family
FOB70_RS20370	COG0513	Belongs to the DEAD box helicase family
FOB70_RS20375	COG2153	protein acetylation
FOB70_RS20385	COG0545	Peptidyl-prolyl cis-trans isomerase
FOB70_RS20395	COG0203	ribosomal protein L17
FOB70_RS20400	COG0202	RNA polymerase activity
FOB70_RS20410	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FOB70_RS20415	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FOB70_RS20420	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FOB70_RS20425	COG0201	protein transport
FOB70_RS20430	COG0200	Binds to the 23S rRNA
FOB70_RS20435	COG1841	ribosomal large subunit assembly
FOB70_RS20450	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FOB70_RS20455	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FOB70_RS20460	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FOB70_RS20465	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FOB70_RS20470	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FOB70_RS20475	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FOB70_RS20480	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FOB70_RS20485	COG0255	Belongs to the universal ribosomal protein uL29 family
FOB70_RS20495	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FOB70_RS20500	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FOB70_RS20505	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FOB70_RS20510	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FOB70_RS20520	COG0088	Forms part of the polypeptide exit tunnel
FOB70_RS20525	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FOB70_RS20535	COG0254	rRNA binding
FOB70_RS20545	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FOB70_RS20550	COG1609	Transcriptional regulator
FOB70_RS20560	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FOB70_RS20565	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FOB70_RS20570	COG1575	Belongs to the MenA family. Type 1 subfamily
FOB70_RS20575	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FOB70_RS20580	COG3074	FtsZ-dependent cytokinesis
FOB70_RS20590	COG1494	fructose-1,6-bisphosphatase
FOB70_RS20615	COG0149	triose-phosphate isomerase activity
FOB70_RS20620	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FOB70_RS20640	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FOB70_RS20655	COG1482	cell wall glycoprotein biosynthetic process
FOB70_RS20675	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOB70_RS20680	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
FOB70_RS20685	COG0438	transferase activity, transferring glycosyl groups
FOB70_RS20775	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FOB70_RS20785	COG1560	Kdo2-lipid A biosynthetic process
FOB70_RS20805	COG1519	Transferase
FOB70_RS20815	COG1028	Short-chain dehydrogenase reductase Sdr
FOB70_RS20865	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FOB70_RS20875	COG3642	lipopolysaccharide core region biosynthetic process
FOB70_RS20880	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FOB70_RS20885	COG0859	PFAM glycosyl transferase family 9
FOB70_RS20890	COG0463	Glycosyl transferase, family 2
FOB70_RS20905	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FOB70_RS20910	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FOB70_RS20920	COG2194	sulfuric ester hydrolase activity
FOB70_RS20930	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FOB70_RS20935	COG2003	Belongs to the UPF0758 family
FOB70_RS20950	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FOB70_RS20955	COG1309	transcriptional regulator
FOB70_RS20960	COG1560	Kdo2-lipid A biosynthetic process
FOB70_RS20965	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FOB70_RS20970	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FOB70_RS20975	COG1561	YicC-like family, N-terminal region
FOB70_RS20995	COG2003	Belongs to the UPF0758 family
FOB70_RS21060	COG0328	RNA-DNA hybrid ribonuclease activity
FOB70_RS21105	COG4608	Belongs to the ABC transporter superfamily
FOB70_RS21110	COG0444	Belongs to the ABC transporter superfamily
FOB70_RS21115	COG0747	negative chemotaxis
FOB70_RS21120	COG4239	(ABC) transporter, permease
FOB70_RS21125	COG4174	ABC transporter (Permease)
FOB70_RS21150	COG0811	peptide transport
FOB70_RS21155	COG0848	biopolymer transport protein
FOB70_RS21170	COG0194	GDP metabolic process
FOB70_RS21175	COG1758	RNA polymerase activity
FOB70_RS21180	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FOB70_RS21185	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FOB70_RS21190	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FOB70_RS21200	COG2233	PERMEase
FOB70_RS21220	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FOB70_RS21230	COG2183	response to ionizing radiation
FOB70_RS21240	COG0596	Alpha beta hydrolase
FOB70_RS21245	COG1040	competence protein
FOB70_RS21250	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FOB70_RS21250	COG0316	Belongs to the HesB IscA family
FOB70_RS21255	COG0494	nUDIX hydrolase
FOB70_RS21260	COG1218	3'(2'),5'-bisphosphate nucleotidase
FOB70_RS21270	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
FOB70_RS21275	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
FOB70_RS21280	COG3156	type II secretion system protein K
FOB70_RS21285	COG4795	General secretion pathway protein
FOB70_RS21290	COG2165	general secretion pathway protein
FOB70_RS21295	COG2165	general secretion pathway protein
FOB70_RS21300	COG2165	general secretion pathway protein
FOB70_RS21305	COG1459	type II secretion system
FOB70_RS21310	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FOB70_RS21320	COG3031	protein transport across the cell outer membrane
FOB70_RS21325	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FOB70_RS21330	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FOB70_RS21335	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FOB70_RS21345	COG0456	acetyltransferase
FOB70_RS21350	COG1490	D-aminoacyl-tRNA deacylase activity
FOB70_RS21355	COG1295	ribonuclease BN
FOB70_RS21370	COG1217	gtp-binding protein TYPA
FOB70_RS21375	COG0174	glutamine synthetase
FOB70_RS21385	COG3852	Histidine kinase
FOB70_RS21390	COG2204	response regulator
FOB70_RS21400	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FOB70_RS21435	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FOB70_RS21445	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOB70_RS21445	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOB70_RS21470	COG0084	hydrolase, TatD family'
FOB70_RS21480	COG0805	protein transport
FOB70_RS21485	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FOB70_RS21490	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FOB70_RS21495	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FOB70_RS21500	COG3165	ubiquinone biosynthetic process from chorismate
FOB70_RS21505	COG2226	methyltransferase
FOB70_RS21510	COG1322	Protein conserved in bacteria
FOB70_RS21525	COG0628	permease
FOB70_RS21575	COG2823	Periplasmic or secreted lipoprotein
FOB70_RS21585	COG2081	HI0933 family
FOB70_RS21595	COG1528	Iron-storage protein
FOB70_RS21600	COG0589	response to stress
FOB70_RS21615	COG0742	ribosomal rna small subunit methyltransferase
FOB70_RS21620	COG5001	Diguanylate cyclase
FOB70_RS21620	COG5002	protein histidine kinase activity
FOB70_RS21625	COG1522	sequence-specific DNA binding
FOB70_RS21630	COG0339	signal peptide processing
FOB70_RS21640	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FOB70_RS21645	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOB70_RS21650	COG0583	DNA-binding transcription factor activity
FOB70_RS21655	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FOB70_RS21660	COG0800	Aldolase
FOB70_RS21665	COG2610	gluconate transmembrane transporter activity
FOB70_RS21670	COG3265	gluconokinase activity
FOB70_RS21675	COG0129	dihydroxy-acid dehydratase activity
FOB70_RS21690	COG0583	DNA-binding transcription factor activity
FOB70_RS21695	COG1609	Transcriptional regulator
FOB70_RS21735	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOB70_RS21740	COG0601	transmembrane transport
FOB70_RS21745	COG0747	negative chemotaxis
FOB70_RS21750	COG4172	Belongs to the ABC transporter superfamily
FOB70_RS21815	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOB70_RS21820	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOB70_RS21830	COG2960	long-chain fatty acid transporting porin activity
FOB70_RS21835	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FOB70_RS21840	COG0583	DNA-binding transcription factor activity
FOB70_RS21875	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FOB70_RS21885	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FOB70_RS21890	COG0408	coproporphyrinogen oxidase activity
FOB70_RS21895	COG0009	L-threonylcarbamoyladenylate synthase
FOB70_RS21900	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FOB70_RS21905	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FOB70_RS21910	COG0551	DNA topoisomerase type I activity
FOB70_RS21915	COG2922	Belongs to the Smg family
FOB70_RS21920	COG0758	DNA mediated transformation
FOB70_RS21930	COG0242	peptide deformylase activity
FOB70_RS21935	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FOB70_RS21940	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FOB70_RS21940	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FOB70_RS21945	COG0569	domain protein
FOB70_RS21950	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FOB70_RS21960	COG1272	protein, Hemolysin III
FOB70_RS21965	COG4326	sporulation control protein
FOB70_RS21975	COG3084	Protein conserved in bacteria
FOB70_RS21985	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FOB70_RS21990	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FOB70_RS21995	COG0204	Acyl-transferase
FOB70_RS22005	COG0606	chelatase, subunit chli
FOB70_RS22015	COG3978	acetolactate synthase activity
FOB70_RS22020	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FOB70_RS22025	COG0129	dihydroxy-acid dehydratase activity
FOB70_RS22035	COG0583	DNA-binding transcription factor activity
FOB70_RS22040	COG2814	Major facilitator Superfamily
FOB70_RS22045	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOB70_RS22050	COG0765	amino acid transport
FOB70_RS22055	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FOB70_RS22060	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FOB70_RS22065	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FOB70_RS22070	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FOB70_RS22075	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FOB70_RS22080	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FOB70_RS22095	COG0356	it plays a direct role in the translocation of protons across the membrane
FOB70_RS22100	COG3312	ion transport
FOB70_RS22105	COG1475	DNA binding
FOB70_RS22110	COG1192	Involved in chromosome partitioning
FOB70_RS22115	COG0357	Ribosomal RNA small subunit methyltransferase G
FOB70_RS22120	COG0445	tRNA wobble uridine modification
FOB70_RS22125	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FOB70_RS22180	COG3645	SOS response
FOB70_RS22185	COG3645	SOS response
FOB70_RS22195	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FOB70_RS22230	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FOB70_RS22235	COG0706	membrane insertase activity
FOB70_RS22245	COG0594	ribonuclease P activity
FOB70_RS22255	COG1126	abc transporter atp-binding protein
FOB70_RS22280	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FOB70_RS22285	COG0592	DNA-directed DNA polymerase activity
FOB70_RS22290	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FOB70_RS22295	COG0187	DNA topoisomerase II activity
FOB70_RS22315	COG0071	Belongs to the small heat shock protein (HSP20) family
FOB70_RS22320	COG3977	Valine--pyruvate aminotransferase
FOB70_RS22325	COG0366	Alpha amylase catalytic
FOB70_RS22330	COG0751	glycine-tRNA ligase activity
FOB70_RS22335	COG0752	glycyl-tRNA synthetase alpha subunit
FOB70_RS22340	COG2119	membrane
FOB70_RS22350	COG0425	Belongs to the sulfur carrier protein TusA family
FOB70_RS22365	COG0604	alcohol dehydrogenase
FOB70_RS22370	COG0183	Belongs to the thiolase family
FOB70_RS22375	COG1250	3-hydroxyacyl-CoA dehydrogenase
FOB70_RS22375	COG1024	Enoyl-CoA hydratase
FOB70_RS22380	COG1739	Uncharacterized protein family UPF0029
FOB70_RS22385	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FOB70_RS22475	COG3335	DDE superfamily endonuclease
FOB70_RS22480	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FOB70_RS22485	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FOB70_RS22490	COG0352	thiamine-phosphate diphosphorylase activity
FOB70_RS22495	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FOB70_RS22500	COG2104	thiamine diphosphate biosynthetic process
FOB70_RS22505	COG2022	thiamine diphosphate biosynthetic process
FOB70_RS22515	COG0006	proline dipeptidase activity
FOB70_RS22515	COG0006	proline dipeptidase activity
FOB70_RS22545	COG3220	belongs to the UPF0276 family
FOB70_RS22555	COG0210	DNA helicase
FOB70_RS22565	COG0405	Gamma-glutamyltransferase
FOB70_RS22570	COG1280	lysine exporter protein (LysE YggA)
FOB70_RS22580	COG2962	Rard protein
FOB70_RS22585	COG0514	ATP-dependent DNA helicase (RecQ)
FOB70_RS22600	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FOB70_RS22605	COG0248	Ppx GppA phosphatase
FOB70_RS22610	COG0513	Belongs to the DEAD box helicase family
FOB70_RS22615	COG3118	belongs to the thioredoxin family
FOB70_RS22635	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FOB70_RS22640	COG0633	Ferredoxin
FOB70_RS22690	COG3071	HemY protein
FOB70_RS22695	COG2959	enzyme of heme biosynthesis
FOB70_RS22700	COG1587	Uroporphyrinogen-III synthase
FOB70_RS22705	COG0181	hydroxymethylbilane synthase activity
FOB70_RS22710	COG3072	Adenylate cyclase
FOB70_RS22715	COG1965	Belongs to the frataxin family
FOB70_RS22725	COG0019	diaminopimelate decarboxylase activity
FOB70_RS22730	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FOB70_RS22740	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FOB70_RS22745	COG1011	Hydrolase
FOB70_RS22750	COG2199	diguanylate cyclase activity
FOB70_RS22750	COG2200	EAL domain
FOB70_RS22750	COG3287	FIST C domain
FOB70_RS22755	COG3148	PFAM DTW domain containing protein
FOB70_RS22770	COG0561	phosphatase activity
FOB70_RS22780	COG2267	carboxylic ester hydrolase activity
FOB70_RS22785	COG1280	lysine exporter protein (LysE YggA)
FOB70_RS22790	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FOB70_RS22795	COG0640	Transcriptional regulator
FOB70_RS22800	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FOB70_RS22855	COG2095	MarC family integral membrane protein
FOB70_RS22865	COG0742	ribosomal rna small subunit methyltransferase
FOB70_RS22870	COG0552	protein localization to endoplasmic reticulum
FOB70_RS22875	COG2884	Cell division ATP-binding protein ftsE
FOB70_RS22880	COG2177	Part of the ABC transporter FtsEX involved in
FOB70_RS22895	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOB70_RS22900	COG0705	Rhomboid family
FOB70_RS22905	COG1580	Controls the rotational direction of flagella during chemotaxis
FOB70_RS22910	COG3161	chorismate lyase activity
FOB70_RS22915	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FOB70_RS22920	COG2937	Belongs to the GPAT DAPAT family
FOB70_RS22930	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FOB70_RS22935	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
FOB70_RS22940	COG0534	Mate efflux family protein
FOB70_RS22945	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOB70_RS22960	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FOB70_RS22965	COG4206	TonB-dependent receptor
FOB70_RS22975	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FOB70_RS23005	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOB70_RS23015	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FOB70_RS23050	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FOB70_RS23060	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FOB70_RS23065	COG0250	Participates in transcription elongation, termination and antitermination
FOB70_RS23070	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FOB70_RS23075	COG0081	regulation of translation
FOB70_RS23080	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FOB70_RS23085	COG0222	ribosome binding
FOB70_RS23090	COG0085	RNA polymerase activity
FOB70_RS23095	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FOB70_RS23100	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
FOB70_RS23105	COG2816	NAD+ diphosphatase activity
FOB70_RS23120	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FOB70_RS23125	COG1573	uracil-dna glycosylase
FOB70_RS23130	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FOB70_RS23140	COG1253	flavin adenine dinucleotide binding
FOB70_RS23155	COG0151	Belongs to the GarS family
FOB70_RS23165	COG0138	bifunctional purine biosynthesis protein purh
FOB70_RS23175	COG0789	Transcriptional regulator
FOB70_RS23180	COG3710	Transcriptional regulator
FOB70_RS23190	COG0531	amino acid
FOB70_RS23195	COG1982	Orn Lys Arg decarboxylase major
FOB70_RS23270	COG3706	GGDEF domain
FOB70_RS23275	COG0488	(ABC) transporter
FOB70_RS23280	COG2814	Major facilitator Superfamily
FOB70_RS23285	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FOB70_RS23290	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FOB70_RS23295	COG2264	protein methyltransferase activity
FOB70_RS23305	COG0439	Biotin carboxylase
FOB70_RS23310	COG0511	ligase activity, forming carbon-carbon bonds
FOB70_RS23315	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FOB70_RS23320	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FOB70_RS23335	COG2814	Major facilitator Superfamily
FOB70_RS23340	COG0784	Response regulator, receiver
FOB70_RS23340	COG2205	protein histidine kinase activity
FOB70_RS23365	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FOB70_RS23375	COG3263	regulation of cellular component size
FOB70_RS23385	COG4232	protein-disulfide reductase activity
FOB70_RS23390	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FOB70_RS23395	COG1027	Aspartate ammonia-lyase
FOB70_RS23400	COG3030	protein affecting phage T7 exclusion by the F plasmid
FOB70_RS23405	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FOB70_RS23415	COG2205	protein histidine kinase activity
FOB70_RS23420	COG0745	RESPONSE REGULATOR receiver
FOB70_RS23430	COG3678	ATP-independent chaperone mediated protein folding
FOB70_RS23440	COG0205	6-phosphofructokinase activity
FOB70_RS23445	COG0534	Mate efflux family protein
FOB70_RS23455	COG0459	protein refolding
FOB70_RS23470	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FOB70_RS23485	COG1509	lysine 2,3-aminomutase activity
FOB70_RS23490	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FOB70_RS23500	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
FOB70_RS23505	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
FOB70_RS23510	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FOB70_RS23515	COG1053	succinate dehydrogenase
FOB70_RS23525	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
FOB70_RS23545	COG4942	peptidase
FOB70_RS23550	COG1045	serine acetyltransferase
FOB70_RS23555	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FOB70_RS23560	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FOB70_RS23565	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOB70_RS23575	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FOB70_RS23590	COG0471	metal ion transport
FOB70_RS23595	COG0688	phosphatidylethanolamine metabolic process
FOB70_RS23600	COG1162	GTPase activity
FOB70_RS23605	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FOB70_RS23675	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FOB70_RS23680	COG0802	atpase or kinase
FOB70_RS23685	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOB70_RS23690	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FOB70_RS23695	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FOB70_RS23705	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FOB70_RS23710	COG0330	HflC and HflK could
FOB70_RS23715	COG0330	HflC and HflK could
FOB70_RS23720	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
FOB70_RS23725	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FOB70_RS23735	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
FOB70_RS23740	COG1017	nitric oxide dioxygenase activity
FOB70_RS23740	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FOB70_RS23745	COG1959	2 iron, 2 sulfur cluster binding
FOB70_RS23750	COG0557	exoribonuclease II activity
FOB70_RS23755	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FOB70_RS23760	COG0546	phosphoglycolate phosphatase activity
FOB70_RS23765	COG0180	Tryptophanyl-tRNA synthetase
FOB70_RS23795	COG0512	Glutamine amidotransferase of anthranilate synthase
FOB70_RS23800	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FOB70_RS23810	COG1012	belongs to the aldehyde dehydrogenase family
FOB70_RS23820	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FOB70_RS23825	COG3954	Phosphoribulokinase
FOB70_RS23830	COG3089	Belongs to the UPF0270 family
FOB70_RS23835	COG0429	hydrolase of the alpha beta-hydrolase fold
FOB70_RS23845	COG0488	(ABC) transporter
FOB70_RS23855	COG2249	NAD(P)H dehydrogenase (quinone) activity
FOB70_RS23870	COG1047	Peptidyl-prolyl cis-trans
FOB70_RS23880	COG1446	asparaginase
FOB70_RS23885	COG2900	Belongs to the SlyX family
FOB70_RS23895	COG0545	Peptidyl-prolyl cis-trans isomerase
FOB70_RS23900	COG2964	Protein conserved in bacteria
FOB70_RS23905	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
FOB70_RS23910	COG2923	Belongs to the DsrF TusC family
FOB70_RS23915	COG2168	tRNA wobble position uridine thiolation
FOB70_RS23925	COG0049	tRNA binding
FOB70_RS23930	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FOB70_RS23935	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FOB70_RS23940	COG2906	2 iron, 2 sulfur cluster binding
FOB70_RS23950	COG0281	malic enzyme
FOB70_RS23960	COG0626	cystathionine gamma-synthase activity
FOB70_RS23965	COG0527	aspartate kinase activity
FOB70_RS23965	COG0460	homoserine dehydrogenase
FOB70_RS23970	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FOB70_RS23975	COG1695	Transcriptional regulator
FOB70_RS23980	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FOB70_RS23985	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOB70_RS23990	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FOB70_RS23995	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FOB70_RS24000	COG0137	argininosuccinate synthase activity
FOB70_RS24005	COG0165	Argininosuccinate lyase
FOB70_RS24005	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FOB70_RS24020	COG0678	peroxiredoxin activity
FOB70_RS24020	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FOB70_RS24030	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FOB70_RS24060	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FOB70_RS24065	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FOB70_RS24075	COG0338	D12 class N6 adenine-specific DNA methyltransferase
FOB70_RS24080	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FOB70_RS24085	COG0360	Binds together with S18 to 16S ribosomal RNA
FOB70_RS24090	COG2965	DNA replication, synthesis of RNA primer
FOB70_RS24100	COG0359	binds to the 23S rRNA
FOB70_RS24115	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FOB70_RS24125	COG0432	Pfam Uncharacterised protein family UPF0047
FOB70_RS24130	COG0166	Belongs to the GPI family
FOB70_RS24140	COG0735	belongs to the Fur family
FOB70_RS24150	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FOB70_RS24175	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FOB70_RS24180	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FOB70_RS24185	COG0175	sulfate reduction
FOB70_RS24265	COG1410	methionine synthase
FOB70_RS24265	COG0646	methionine synthase
FOB70_RS24270	COG0527	aspartate kinase activity
FOB70_RS24280	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FOB70_RS24290	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FOB70_RS24305	COG0629	single-stranded DNA binding
FOB70_RS24310	COG2200	EAL domain
FOB70_RS24310	COG2199	diguanylate cyclase activity
FOB70_RS24335	COG3409	Peptidoglycan-binding domain 1 protein
FOB70_RS24335	COG3267	Type II secretory pathway component ExeA
FOB70_RS24345	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FOB70_RS24350	COG1459	type II secretion system
FOB70_RS24360	COG2165	general secretion pathway protein
FOB70_RS24395	COG1077	Cell shape determining protein MreB Mrl
FOB70_RS24400	COG1792	Involved in formation and maintenance of cell shape
FOB70_RS24405	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FOB70_RS24410	COG0424	maF-like protein
FOB70_RS24420	COG3164	Protein of unknown function
FOB70_RS24425	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FOB70_RS24430	COG0312	modulator of DNA gyrase
FOB70_RS24435	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FOB70_RS24440	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FOB70_RS24455	COG0564	pseudouridine synthase activity
FOB70_RS24460	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FOB70_RS24465	COG3028	Belongs to the UPF0307 family
FOB70_RS24470	COG0312	modulator of DNA gyrase
FOB70_RS24475	COG2239	Acts as a magnesium transporter
FOB70_RS24480	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOB70_RS24485	COG1660	Displays ATPase and GTPase activities
FOB70_RS24490	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOB70_RS24495	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FOB70_RS24505	COG1137	ATPase activity
FOB70_RS24510	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FOB70_RS24520	COG0517	IMP dehydrogenase activity
FOB70_RS24520	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FOB70_RS24530	COG1127	ABC transporter
FOB70_RS24535	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FOB70_RS24540	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FOB70_RS24545	COG2854	intermembrane phospholipid transfer
FOB70_RS24555	COG5007	Belongs to the BolA IbaG family
FOB70_RS24560	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FOB70_RS24565	COG0204	Acyl-transferase
FOB70_RS24570	COG0251	oxidation-reduction process
FOB70_RS24575	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
FOB70_RS24580	COG0540	Belongs to the ATCase OTCase family
FOB70_RS24590	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FOB70_RS24595	COG2235	arginine
FOB70_RS24625	COG0525	valine-tRNA ligase activity
FOB70_RS24630	COG2927	DNA polymerase III (CHI subunit)
FOB70_RS24635	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FOB70_RS24640	COG0795	lipopolysaccharide-transporting ATPase activity
FOB70_RS24645	COG0795	lipopolysaccharide-transporting ATPase activity
FOB70_RS24670	COG0726	polysaccharide deacetylase
FOB70_RS24675	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOB70_RS24680	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOB70_RS24685	COG1447	Phosphotransferase system cellobiose-specific component IIA
FOB70_RS24690	COG1486	melibiose metabolic process
FOB70_RS24695	COG3394	polysaccharide catabolic process
FOB70_RS24705	COG3437	response regulator, receiver
FOB70_RS24755	COG1012	belongs to the aldehyde dehydrogenase family
FOB70_RS24825	COG0741	lytic transglycosylase activity
FOB70_RS24830	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
FOB70_RS24840	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FOB70_RS24850	COG2066	Belongs to the glutaminase family
FOB70_RS24855	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FOB70_RS24860	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FOB70_RS24870	COG1872	DUF167
FOB70_RS24875	COG0762	integral membrane protein
FOB70_RS24880	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FOB70_RS24885	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FOB70_RS24900	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FOB70_RS24905	COG1678	Uncharacterized ACR, COG1678
FOB70_RS24910	COG0189	ligase activity
FOB70_RS24915	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FOB70_RS24920	COG2356	endonuclease I
FOB70_RS24925	COG3091	SprT-like family
FOB70_RS24935	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FOB70_RS24945	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FOB70_RS24950	COG0583	DNA-binding transcription factor activity
FOB70_RS24955	COG4771	TonB-dependent receptor
FOB70_RS24960	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FOB70_RS24965	COG0126	phosphoglycerate kinase activity
FOB70_RS24970	COG0191	fructose-bisphosphate aldolase activity
FOB70_RS24975	COG0668	transmembrane transport
FOB70_RS24980	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FOB70_RS24990	COG0583	DNA-binding transcription factor activity
FOB70_RS25000	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FOB70_RS25005	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FOB70_RS25010	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FOB70_RS25020	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
FOB70_RS25030	COG3079	Belongs to the UPF0149 family
FOB70_RS25035	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FOB70_RS25040	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FOB70_RS25055	COG0354	folic acid binding
FOB70_RS25060	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FOB70_RS25070	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FOB70_RS25080	COG1595	DNA-templated transcription, initiation
FOB70_RS25085	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
FOB70_RS25095	COG3086	response to oxidative stress
FOB70_RS25100	COG0481	GTPase activity
FOB70_RS25110	COG0571	ribonuclease III activity
FOB70_RS25115	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FOB70_RS25120	COG1381	Involved in DNA repair and RecF pathway recombination
FOB70_RS25125	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FOB70_RS25130	COG0736	holo-[acyl-carrier-protein] synthase activity
FOB70_RS25145	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FOB70_RS25155	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FOB70_RS25160	COG3956	TIGRFAM MazG family protein
FOB70_RS25165	COG0504	CTP synthase activity
FOB70_RS25170	COG0148	phosphopyruvate hydratase activity
FOB70_RS25175	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
FOB70_RS25180	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FOB70_RS25185	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FOB70_RS25190	COG0585	pseudouridine synthase activity
FOB70_RS25195	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FOB70_RS25200	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FOB70_RS25215	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FOB70_RS25220	COG1546	Belongs to the CinA family
FOB70_RS25225	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FOB70_RS25230	COG2137	regulation of response to DNA damage stimulus
FOB70_RS25235	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FOB70_RS25240	COG0527	aspartate kinase activity
FOB70_RS25300	COG3630	sodium ion export across plasma membrane
FOB70_RS25305	COG5016	pyruvate
FOB70_RS25305	COG0511	ligase activity, forming carbon-carbon bonds
FOB70_RS25310	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
FOB70_RS25320	COG1238	metal cluster binding
FOB70_RS25325	COG0612	Peptidase, M16
FOB70_RS25330	COG2918	glutathione biosynthetic process
FOB70_RS25340	COG1854	S-ribosylhomocysteine lyase activity
FOB70_RS25345	COG4536	flavin adenine dinucleotide binding
FOB70_RS25350	COG4137	Cytochrome C assembly protein
FOB70_RS25355	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FOB70_RS25360	COG0228	four-way junction DNA binding
FOB70_RS25365	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FOB70_RS25370	COG0336	Belongs to the RNA methyltransferase TrmD family
FOB70_RS25375	COG0335	large ribosomal subunit rRNA binding
FOB70_RS25380	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FOB70_RS25385	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
FOB70_RS25390	COG0237	dephospho-CoA kinase activity
FOB70_RS25400	COG1459	type II secretion system
FOB70_RS25405	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FOB70_RS25410	COG4969	Belongs to the N-Me-Phe pilin family
FOB70_RS25415	COG0157	Belongs to the NadC ModD family
FOB70_RS25425	COG2186	Transcriptional regulator
FOB70_RS25430	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FOB70_RS25435	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOB70_RS25440	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOB70_RS25455	COG0288	reversible hydration of carbon dioxide
FOB70_RS25460	COG0659	secondary active sulfate transmembrane transporter activity
FOB70_RS25470	COG1131	(ABC) transporter
FOB70_RS25475	COG0842	Transport permease protein
FOB70_RS25485	COG1560	Kdo2-lipid A biosynthetic process
FOB70_RS25495	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FOB70_RS25500	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FOB70_RS25505	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FOB70_RS25520	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FOB70_RS25535	COG1489	DNA binding
FOB70_RS25540	COG1643	Atp-dependent helicase
FOB70_RS25545	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOB70_RS25550	COG1752	Esterase of the alpha-beta hydrolase superfamily
FOB70_RS25555	COG1049	propionate catabolic process, 2-methylcitrate cycle
FOB70_RS25560	COG3112	Uncharacterised protein family (UPF0231)
FOB70_RS25570	COG0004	ammonium transporteR
FOB70_RS25575	COG1840	ABC-type Fe3 transport system, periplasmic component
FOB70_RS25585	COG3842	ATPase activity
FOB70_RS25590	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FOB70_RS25605	COG2971	BadF BadG BcrA BcrD
FOB70_RS25615	COG4608	Belongs to the ABC transporter superfamily
FOB70_RS25620	COG0444	Belongs to the ABC transporter superfamily
FOB70_RS25625	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOB70_RS25635	COG0747	negative chemotaxis