locus-tag	class	description
FOB75_RS00015	COG0583	DNA-binding transcription factor activity
FOB75_RS00020	COG0531	amino acid
FOB75_RS00025	COG2731	YhcH YjgK YiaL family protein
FOB75_RS00030	COG3250	beta-galactosidase activity
FOB75_RS00035	COG1609	Transcriptional regulator
FOB75_RS00045	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FOB75_RS00055	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FOB75_RS00060	COG2017	converts alpha-aldose to the beta-anomer
FOB75_RS00075	COG2211	Major facilitator Superfamily
FOB75_RS00080	COG1609	Transcriptional regulator
FOB75_RS00085	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOB75_RS00100	COG0598	Magnesium transport protein CorA
FOB75_RS00105	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FOB75_RS00110	COG1349	DNA-binding transcription factor activity
FOB75_RS00115	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FOB75_RS00120	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FOB75_RS00135	COG2271	Major facilitator Superfamily
FOB75_RS00140	COG0584	glycerophosphoryl diester phosphodiesterase
FOB75_RS00145	COG2171	N-acyltransferase activity
FOB75_RS00150	COG3141	response to X-ray
FOB75_RS00170	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FOB75_RS00180	COG1074	ATP-dependent DNA helicase activity
FOB75_RS00185	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FOB75_RS00205	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FOB75_RS00205	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FOB75_RS00220	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FOB75_RS00225	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FOB75_RS00230	COG2166	iron-sulfur cluster assembly
FOB75_RS00240	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FOB75_RS00245	COG0693	protein deglycase activity
FOB75_RS00250	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FOB75_RS00255	COG3248	Nucleoside-binding outer membrane protein
FOB75_RS00275	COG1595	DNA-templated transcription, initiation
FOB75_RS00295	COG3056	Lipoprotein
FOB75_RS00300	COG2813	Specifically methylates the guanine in position
FOB75_RS00305	COG0271	Belongs to the BolA IbaG family
FOB75_RS00310	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FOB75_RS00315	COG1805	sodium ion transport
FOB75_RS00320	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FOB75_RS00325	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FOB75_RS00330	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FOB75_RS00335	COG2871	sodium ion transport
FOB75_RS00340	COG1477	protein flavinylation
FOB75_RS00355	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FOB75_RS00360	COG0514	ATP-dependent DNA helicase (RecQ)
FOB75_RS00365	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FOB75_RS00380	COG0733	neurotransmitter:sodium symporter activity
FOB75_RS00400	COG0442	prolyl-tRNA aminoacylation
FOB75_RS00405	COG1720	tRNA m6t6A37 methyltransferase activity
FOB75_RS00410	COG0254	rRNA binding
FOB75_RS00425	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
FOB75_RS00430	COG1671	Belongs to the UPF0178 family
FOB75_RS00455	COG3098	single-species biofilm formation
FOB75_RS00460	COG0564	pseudouridine synthase activity
FOB75_RS00470	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FOB75_RS00475	COG0024	Methionine aminopeptidase
FOB75_RS00480	COG0052	Belongs to the universal ribosomal protein uS2 family
FOB75_RS00485	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FOB75_RS00490	COG0528	UMP kinase activity
FOB75_RS00495	COG0233	cytoplasmic translational termination
FOB75_RS00500	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FOB75_RS00505	COG0575	Belongs to the CDS family
FOB75_RS00510	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FOB75_RS00515	COG0750	zinc metalloprotease
FOB75_RS00525	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
FOB75_RS00530	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FOB75_RS00535	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FOB75_RS00540	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FOB75_RS00545	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FOB75_RS00550	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FOB75_RS00555	COG0587	DNA-directed DNA polymerase activity
FOB75_RS00560	COG0825	malonyl-CoA metabolic process
FOB75_RS00565	COG0037	tRNA processing
FOB75_RS00575	COG0347	Belongs to the P(II) protein family
FOB75_RS00580	COG3021	interspecies interaction between organisms
FOB75_RS00590	COG0741	lytic transglycosylase activity
FOB75_RS00590	COG1388	LysM domain
FOB75_RS00595	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOB75_RS00600	COG2226	methyltransferase
FOB75_RS00605	COG0328	RNA-DNA hybrid ribonuclease activity
FOB75_RS00610	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FOB75_RS00625	COG1960	acyl-CoA dehydrogenase activity
FOB75_RS00630	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FOB75_RS00635	COG0121	glutamine amidotransferase
FOB75_RS00640	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FOB75_RS00645	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FOB75_RS00650	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FOB75_RS00655	COG2233	PERMEase
FOB75_RS00675	COG1393	Belongs to the ArsC family
FOB75_RS00680	COG4783	chaperone-mediated protein folding
FOB75_RS00695	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FOB75_RS00700	COG2716	regulation of RNA biosynthetic process
FOB75_RS00705	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FOB75_RS00710	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
FOB75_RS00725	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOB75_RS00730	COG1393	Belongs to the ArsC family
FOB75_RS00760	COG2837	iron assimilation
FOB75_RS00765	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FOB75_RS00775	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FOB75_RS00780	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FOB75_RS00785	COG1334	flagellar protein FlaG
FOB75_RS00790	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FOB75_RS00800	COG1516	flagellar protein fliS
FOB75_RS00825	COG1677	Flagellar hook-basal body complex protein FliE
FOB75_RS00835	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FOB75_RS00885	COG1987	bacterial-type flagellum assembly
FOB75_RS00890	COG1684	flagellar biosynthetic protein fliR
FOB75_RS00925	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
FOB75_RS00930	COG0784	Response regulator, receiver
FOB75_RS00930	COG2198	Histidine kinase
FOB75_RS00930	COG0643	Histidine kinase
FOB75_RS00935	COG2201	protein-glutamate methylesterase activity
FOB75_RS00940	COG1192	Involved in chromosome partitioning
FOB75_RS00950	COG0835	chemotaxis
FOB75_RS00960	COG4133	protoheme IX ABC transporter activity
FOB75_RS00965	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FOB75_RS00970	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FOB75_RS00975	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FOB75_RS00980	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
FOB75_RS00985	COG1138	Cytochrome C-type biogenesis protein
FOB75_RS00990	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOB75_RS01005	COG2853	Lipoprotein
FOB75_RS01035	COG0183	Belongs to the thiolase family
FOB75_RS01040	COG1024	Enoyl-CoA hydratase
FOB75_RS01040	COG1250	3-hydroxyacyl-CoA dehydrogenase
FOB75_RS01055	COG2062	phosphohistidine phosphatase, SixA
FOB75_RS01060	COG2840	Smr protein MutS2
FOB75_RS01065	COG2890	protein-(glutamine-N5) methyltransferase activity
FOB75_RS01070	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FOB75_RS01075	COG2860	membrane
FOB75_RS01085	COG3101	peptidyl-lysine hydroxylation
FOB75_RS01100	COG0431	NADPH-dependent FMN reductase
FOB75_RS01105	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FOB75_RS01105	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOB75_RS01110	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FOB75_RS01120	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FOB75_RS01125	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FOB75_RS01135	COG0101	tRNA pseudouridine synthase activity
FOB75_RS01140	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FOB75_RS01145	COG0285	dihydrofolate synthase activity
FOB75_RS01150	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
FOB75_RS01155	COG1286	toxin biosynthetic process
FOB75_RS01160	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FOB75_RS01165	COG0583	DNA-binding transcription factor activity
FOB75_RS01170	COG0745	RESPONSE REGULATOR receiver
FOB75_RS01180	COG2832	Protein of unknown function (DUF454)
FOB75_RS01185	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FOB75_RS01195	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FOB75_RS01200	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FOB75_RS01205	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FOB75_RS01210	COG0814	amino acid
FOB75_RS01215	COG0251	oxidation-reduction process
FOB75_RS01220	COG3681	Belongs to the UPF0597 family
FOB75_RS01235	COG2261	transglycosylase associated protein
FOB75_RS01240	COG2983	Belongs to the UPF0260 family
FOB75_RS01245	COG0668	transmembrane transport
FOB75_RS01250	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
FOB75_RS01255	COG0346	lactoylglutathione lyase activity
FOB75_RS01265	COG1785	Belongs to the alkaline phosphatase family
FOB75_RS01285	COG2226	methyltransferase
FOB75_RS01295	COG0676	glucose-6-phosphate 1-epimerase activity
FOB75_RS01300	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FOB75_RS01305	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FOB75_RS01315	COG3139	Protein of unknown function (DUF1315)
FOB75_RS01325	COG0252	asparaginase activity
FOB75_RS01330	COG0616	signal peptide processing
FOB75_RS01335	COG1902	pentaerythritol trinitrate reductase activity
FOB75_RS01335	COG0446	pyridine nucleotide-disulphide oxidoreductase
FOB75_RS01340	COG0778	Nitroreductase
FOB75_RS01345	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FOB75_RS01365	COG0123	including yeast histone deacetylase and acetoin utilization protein
FOB75_RS01375	COG3083	sulfuric ester hydrolase activity
FOB75_RS01380	COG3082	Protein of unknown function (DUF1414)
FOB75_RS01385	COG3081	Nucleoid-associated protein
FOB75_RS01400	COG1757	Na H antiporter
FOB75_RS01405	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FOB75_RS01410	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FOB75_RS01415	COG2095	MarC family integral membrane protein
FOB75_RS01420	COG1454	alcohol dehydrogenase
FOB75_RS01420	COG1012	belongs to the aldehyde dehydrogenase family
FOB75_RS01440	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FOB75_RS01450	COG2056	Na+-H+ antiporter family
FOB75_RS01455	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FOB75_RS01470	COG2885	chlorophyll binding
FOB75_RS01480	COG0346	lactoylglutathione lyase activity
FOB75_RS01485	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FOB75_RS01490	COG4660	Part of a membrane complex involved in electron transport
FOB75_RS01495	COG4659	FMN binding
FOB75_RS01500	COG4658	electron transport chain
FOB75_RS01505	COG4656	Part of a membrane complex involved in electron transport
FOB75_RS01510	COG2878	Part of a membrane complex involved in electron transport
FOB75_RS01515	COG4657	Part of a membrane complex involved in electron transport
FOB75_RS01530	COG0556	nucleotide-excision repair
FOB75_RS01535	COG2204	response regulator
FOB75_RS01540	COG2198	Histidine kinase
FOB75_RS01545	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FOB75_RS01550	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FOB75_RS01555	COG0521	Mo-molybdopterin cofactor biosynthetic process
FOB75_RS01560	COG0315	cyclic pyranopterin monophosphate synthase activity
FOB75_RS01565	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FOB75_RS01570	COG0314	molybdopterin synthase activity
FOB75_RS01580	COG0601	transmembrane transport
FOB75_RS01585	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOB75_RS01590	COG0444	Belongs to the ABC transporter superfamily
FOB75_RS01600	COG0435	Glutathione S-transferase
FOB75_RS01610	COG3174	membrane
FOB75_RS01615	COG0857	belongs to the CobB CobQ family
FOB75_RS01615	COG0280	phosphate acetyltransferase
FOB75_RS01620	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FOB75_RS01625	COG3092	negative regulation of chromosome organization
FOB75_RS01635	COG4120	Belongs to the binding-protein-dependent transport system permease family
FOB75_RS01640	COG1122	ATPase activity
FOB75_RS01645	COG0366	Alpha amylase catalytic
FOB75_RS01655	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FOB75_RS01660	COG3318	Belongs to the UPF0149 family
FOB75_RS01660	COG3012	SEC-C Motif Domain Protein
FOB75_RS01665	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FOB75_RS01670	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FOB75_RS01675	COG2186	Transcriptional regulator
FOB75_RS01685	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOB75_RS01685	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOB75_RS01690	COG0489	protein tyrosine kinase activity
FOB75_RS01695	COG0572	uridine kinase
FOB75_RS01705	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
FOB75_RS01710	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FOB75_RS01715	COG0659	secondary active sulfate transmembrane transporter activity
FOB75_RS01725	COG1530	ribonuclease E activity
FOB75_RS01740	COG0564	pseudouridine synthase activity
FOB75_RS01745	COG0424	maF-like protein
FOB75_RS01750	COG1399	metal-binding, possibly nucleic acid-binding protein
FOB75_RS01760	COG0416	fatty acid biosynthetic process
FOB75_RS01765	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOB75_RS01795	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FOB75_RS01800	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FOB75_RS01810	COG0084	hydrolase, TatD family'
FOB75_RS01815	COG1263	PTS System
FOB75_RS01815	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOB75_RS01835	COG0733	neurotransmitter:sodium symporter activity
FOB75_RS01850	COG4667	esterase of the alpha-beta hydrolase superfamily
FOB75_RS01855	COG0469	pyruvate kinase activity
FOB75_RS01860	COG1940	carbohydrate kinase activity
FOB75_RS01865	COG0784	Response regulator, receiver
FOB75_RS01865	COG0835	chemotaxis
FOB75_RS01870	COG0587	DNA-directed DNA polymerase activity
FOB75_RS01885	COG1028	Short-chain dehydrogenase reductase Sdr
FOB75_RS01890	COG0616	signal peptide processing
FOB75_RS01895	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FOB75_RS01900	COG0539	negative regulation of cytoplasmic translation
FOB75_RS01910	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
FOB75_RS01915	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
FOB75_RS01920	COG0284	orotidine-5'-phosphate decarboxylase activity
FOB75_RS01925	COG4166	transmembrane transport
FOB75_RS01950	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FOB75_RS01960	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FOB75_RS01960	COG3008	intermembrane lipid transfer
FOB75_RS01965	COG2995	paraquat-inducible protein a
FOB75_RS01970	COG3258	Cytochrome c
FOB75_RS01975	COG2863	cytochrome
FOB75_RS02015	COG4232	protein-disulfide reductase activity
FOB75_RS02020	COG3118	belongs to the thioredoxin family
FOB75_RS02040	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOB75_RS02050	COG0577	efflux transmembrane transporter activity
FOB75_RS02050	COG1136	(ABC) transporter
FOB75_RS02060	COG0577	efflux transmembrane transporter activity
FOB75_RS02060	COG1136	(ABC) transporter
FOB75_RS02065	COG1335	isochorismatase
FOB75_RS02115	COG3850	Histidine kinase
FOB75_RS02115	COG5002	protein histidine kinase activity
FOB75_RS02120	COG0745	RESPONSE REGULATOR receiver
FOB75_RS02130	COG0840	transmembrane signaling receptor activity
FOB75_RS02135	COG1032	radical SAM domain protein
FOB75_RS02140	COG2203	Gaf domain
FOB75_RS02140	COG3706	GGDEF domain
FOB75_RS02140	COG4251	negative regulation of phosphorylation
FOB75_RS02140	COG5001	Diguanylate cyclase
FOB75_RS02155	COG0583	DNA-binding transcription factor activity
FOB75_RS02165	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FOB75_RS02175	COG2350	Protein conserved in bacteria
FOB75_RS02185	COG2917	probably involved in intracellular septation
FOB75_RS02205	COG1301	dicarboxylic acid transport
FOB75_RS02215	COG0318	PFAM AMP-dependent synthetase and ligase
FOB75_RS02220	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FOB75_RS02230	COG0159	tryptophan synthase activity
FOB75_RS02235	COG0133	tryptophan synthase activity
FOB75_RS02240	COG0134	indole-3-glycerol-phosphate synthase activity
FOB75_RS02240	COG0135	phosphoribosylanthranilate isomerase activity
FOB75_RS02245	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FOB75_RS02250	COG0512	Glutamine amidotransferase of anthranilate synthase
FOB75_RS02255	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FOB75_RS02265	COG0613	PHP domain protein
FOB75_RS02270	COG0009	L-threonylcarbamoyladenylate synthase
FOB75_RS02280	COG1187	pseudouridine synthase activity
FOB75_RS02290	COG3099	Belongs to the UPF0263 family
FOB75_RS02295	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FOB75_RS02305	COG0417	DNA replication proofreading
FOB75_RS02310	COG2197	response regulator
FOB75_RS02315	COG0322	excinuclease ABC activity
FOB75_RS02355	COG0019	diaminopimelate decarboxylase activity
FOB75_RS02380	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FOB75_RS02385	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FOB75_RS02390	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FOB75_RS02410	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
FOB75_RS02420	COG0437	4 iron, 4 sulfur cluster binding
FOB75_RS02425	COG3301	Polysulphide reductase, NrfD
FOB75_RS02430	COG1138	Cytochrome C-type biogenesis protein
FOB75_RS02440	COG4235	cytochrome complex assembly
FOB75_RS02440	COG3088	subunit of a heme lyase
FOB75_RS02450	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FOB75_RS02475	COG2989	Protein conserved in bacteria
FOB75_RS02480	COG3108	Peptidase M15
FOB75_RS02485	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOB75_RS02500	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FOB75_RS02525	COG1846	Transcriptional regulator
FOB75_RS02530	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FOB75_RS02535	COG0840	transmembrane signaling receptor activity
FOB75_RS02555	COG1448	Aminotransferase
FOB75_RS02580	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOB75_RS02590	COG0017	Asparaginyl-tRNA synthetase
FOB75_RS02600	COG0720	synthase
FOB75_RS02610	COG2200	EAL domain
FOB75_RS02615	COG1760	l-serine dehydratase
FOB75_RS02620	COG0814	amino acid
FOB75_RS02625	COG0494	nUDIX hydrolase
FOB75_RS02635	COG0784	Response regulator, receiver
FOB75_RS02635	COG2205	protein histidine kinase activity
FOB75_RS02640	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FOB75_RS02660	COG3106	COG3106 Predicted ATPase
FOB75_RS02665	COG3768	UPF0283 membrane protein
FOB75_RS02675	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOB75_RS03090	COG0456	acetyltransferase
FOB75_RS03140	COG1942	4-Oxalocrotonate Tautomerase
FOB75_RS03550	COG0582	viral genome integration into host DNA
FOB75_RS03575	COG3070	regulator of competence-specific genes
FOB75_RS03605	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOB75_RS03610	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOB75_RS03740	COG3340	Belongs to the peptidase S51 family
FOB75_RS03770	COG2026	Addiction module toxin, RelE StbE family
FOB75_RS03800	COG0729	surface antigen
FOB75_RS03805	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOB75_RS03810	COG2272	Belongs to the type-B carboxylesterase lipase family
FOB75_RS03840	COG2985	domain, Protein
FOB75_RS03850	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
FOB75_RS03865	COG0583	DNA-binding transcription factor activity
FOB75_RS03875	COG0006	proline dipeptidase activity
FOB75_RS03910	COG1757	Na H antiporter
FOB75_RS03915	COG0174	glutamine synthetase
FOB75_RS03925	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FOB75_RS03930	COG1917	Cupin 2, conserved barrel domain protein
FOB75_RS03930	COG1396	sequence-specific DNA binding
FOB75_RS03935	COG1012	belongs to the aldehyde dehydrogenase family
FOB75_RS03940	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOB75_RS03950	COG2957	Belongs to the agmatine deiminase family
FOB75_RS03955	COG1012	belongs to the aldehyde dehydrogenase family
FOB75_RS03960	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FOB75_RS03965	COG1227	inorganic diphosphatase activity
FOB75_RS03975	COG2771	luxR family
FOB75_RS03975	COG2200	EAL domain
FOB75_RS03990	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FOB75_RS04005	COG1846	Transcriptional regulator
FOB75_RS04010	COG2315	Protein conserved in bacteria
FOB75_RS04030	COG0110	maltose O-acetyltransferase activity
FOB75_RS04060	COG3063	Type IV pilus biogenesis stability protein PilW
FOB75_RS04065	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FOB75_RS04080	COG0531	amino acid
FOB75_RS04085	COG1560	Kdo2-lipid A biosynthetic process
FOB75_RS04090	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
FOB75_RS04095	COG1280	lysine exporter protein (LysE YggA)
FOB75_RS04105	COG1115	amino acid carrier protein
FOB75_RS04135	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FOB75_RS04150	COG0814	amino acid
FOB75_RS04175	COG1132	(ABC) transporter
FOB75_RS04180	COG1132	(ABC) transporter
FOB75_RS04210	COG0443	Heat shock 70 kDa protein
FOB75_RS04215	COG0443	Heat shock 70 kDa protein
FOB75_RS04225	COG3706	GGDEF domain
FOB75_RS04255	COG0243	molybdopterin cofactor binding
FOB75_RS04260	COG0437	4 iron, 4 sulfur cluster binding
FOB75_RS04265	COG3302	dmso reductase anchor subunit
FOB75_RS04270	COG3381	protein complex oligomerization
FOB75_RS04280	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FOB75_RS04285	COG1643	Atp-dependent helicase
FOB75_RS04300	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FOB75_RS04310	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FOB75_RS04315	COG1215	transferase activity, transferring glycosyl groups
FOB75_RS04320	COG0438	transferase activity, transferring glycosyl groups
FOB75_RS04355	COG0438	transferase activity, transferring glycosyl groups
FOB75_RS04365	COG2204	response regulator
FOB75_RS04400	COG1793	dna ligase
FOB75_RS04410	COG0534	Mate efflux family protein
FOB75_RS04415	COG0307	riboflavin synthase, alpha
FOB75_RS04425	COG3001	Fructosamine kinase
FOB75_RS04430	COG2201	protein-glutamate methylesterase activity
FOB75_RS04435	COG3706	GGDEF domain
FOB75_RS04445	COG0791	NLP P60 protein
FOB75_RS04450	COG0840	transmembrane signaling receptor activity
FOB75_RS04450	COG3290	protein histidine kinase activity
FOB75_RS04485	COG3148	PFAM DTW domain containing protein
FOB75_RS04490	COG1940	carbohydrate kinase activity
FOB75_RS04500	COG0303	'Molybdopterin
FOB75_RS04505	COG0746	molybdenum cofactor guanylyltransferase activity
FOB75_RS04510	COG3842	ATPase activity
FOB75_RS04530	COG2204	response regulator
FOB75_RS04535	COG4191	Histidine kinase
FOB75_RS04545	COG0488	(ABC) transporter
FOB75_RS04555	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FOB75_RS04580	COG3381	protein complex oligomerization
FOB75_RS04590	COG0243	molybdopterin cofactor binding
FOB75_RS04590	COG3383	formate dehydrogenase (NAD+) activity
FOB75_RS04595	COG0437	4 iron, 4 sulfur cluster binding
FOB75_RS04620	COG0004	ammonium transporteR
FOB75_RS04630	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FOB75_RS04635	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FOB75_RS04645	COG1177	transmembrane transport
FOB75_RS04655	COG3842	ATPase activity
FOB75_RS04675	COG0037	tRNA processing
FOB75_RS04685	COG0589	response to stress
FOB75_RS04690	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FOB75_RS04705	COG2217	Heavy metal translocating P-type atpase
FOB75_RS04715	COG2010	Cytochrome c
FOB75_RS04730	COG3278	Belongs to the heme-copper respiratory oxidase family
FOB75_RS04745	COG0784	Response regulator, receiver
FOB75_RS04745	COG2205	protein histidine kinase activity
FOB75_RS04815	COG3120	sequence-specific DNA binding
FOB75_RS04820	COG1067	ATP-dependent peptidase activity
FOB75_RS04825	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FOB75_RS04840	COG0488	(ABC) transporter
FOB75_RS04850	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FOB75_RS04850	COG0116	Belongs to the methyltransferase superfamily
FOB75_RS04865	COG0167	dihydroorotate dehydrogenase activity
FOB75_RS04870	COG2902	Dehydrogenase
FOB75_RS04880	COG0308	aminopeptidase N
FOB75_RS04895	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
FOB75_RS04900	COG1956	GAF domain-containing protein
FOB75_RS04905	COG1132	(ABC) transporter
FOB75_RS04910	COG2995	paraquat-inducible protein a
FOB75_RS04915	COG3008	intermembrane lipid transfer
FOB75_RS04925	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
FOB75_RS04925	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FOB75_RS04945	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FOB75_RS04950	COG1666	GTP binding
FOB75_RS04970	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOB75_RS04975	COG4597	amino acid ABC transporter
FOB75_RS04980	COG0765	amino acid transport
FOB75_RS04985	COG1126	abc transporter atp-binding protein
FOB75_RS04990	COG0670	Belongs to the BI1 family
FOB75_RS05000	COG2920	part of a sulfur-relay system
FOB75_RS05005	COG1254	Belongs to the acylphosphatase family
FOB75_RS05015	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FOB75_RS05055	COG3706	GGDEF domain
FOB75_RS05060	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FOB75_RS05065	COG0602	queuosine metabolic process
FOB75_RS05070	COG0561	phosphatase activity
FOB75_RS05095	COG2828	Protein conserved in bacteria
FOB75_RS05105	COG0372	Belongs to the citrate synthase family
FOB75_RS05110	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FOB75_RS05140	COG0730	response to heat
FOB75_RS05160	COG0457	Tetratricopeptide repeat
FOB75_RS05230	COG4790	Type iii secretion
FOB75_RS05235	COG4794	Type iii secretion
FOB75_RS05240	COG4791	protein targeting
FOB75_RS05245	COG4792	protein secretion
FOB75_RS05285	COG3177	Filamentation induced by cAMP protein fic
FOB75_RS05305	COG4669	(LipO)protein
FOB75_RS05375	COG1012	belongs to the aldehyde dehydrogenase family
FOB75_RS05380	COG3284	Transcriptional regulator
FOB75_RS05400	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FOB75_RS05405	COG0363	glucosamine-6-phosphate deaminase activity
FOB75_RS05410	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FOB75_RS05415	COG4565	transcriptional regulatory protein
FOB75_RS05420	COG3290	protein histidine kinase activity
FOB75_RS05435	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOB75_RS05450	COG1858	cytochrome C peroxidase
FOB75_RS05455	COG0527	aspartate kinase activity
FOB75_RS05460	COG0662	Cupin 2, conserved barrel domain protein
FOB75_RS05465	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FOB75_RS05470	COG0456	acetyltransferase
FOB75_RS05475	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FOB75_RS05495	COG4176	ABC-type proline glycine betaine transport system permease component
FOB75_RS05500	COG2113	Glycine betaine
FOB75_RS05520	COG1028	Short-chain dehydrogenase reductase Sdr
FOB75_RS05530	COG0745	RESPONSE REGULATOR receiver
FOB75_RS05535	COG0642	Histidine kinase
FOB75_RS05540	COG1368	sulfuric ester hydrolase activity
FOB75_RS05550	COG0861	Integral membrane protein TerC family
FOB75_RS05560	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FOB75_RS05565	COG1328	CTP reductase activity
FOB75_RS05570	COG1280	lysine exporter protein (LysE YggA)
FOB75_RS05580	COG3300	MHYT domain
FOB75_RS05580	COG5001	Diguanylate cyclase
FOB75_RS05590	COG4191	Histidine kinase
FOB75_RS05590	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOB75_RS05595	COG0471	metal ion transport
FOB75_RS05635	COG1278	Cold shock
FOB75_RS05640	COG0557	exoribonuclease II activity
FOB75_RS05695	COG0625	glutathione transferase activity
FOB75_RS05705	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
FOB75_RS05720	COG2195	Cleaves the N-terminal amino acid of tripeptides
FOB75_RS05730	COG0601	transmembrane transport
FOB75_RS05735	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOB75_RS05740	COG0444	Belongs to the ABC transporter superfamily
FOB75_RS05760	COG3291	Pkd domain containing protein
FOB75_RS05775	COG1177	transmembrane transport
FOB75_RS05780	COG1176	ABC-type spermidine putrescine transport system, permease component I
FOB75_RS05785	COG3842	ATPase activity
FOB75_RS05790	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FOB75_RS05795	COG2423	ornithine cyclodeaminase activity
FOB75_RS05815	COG3938	Belongs to the proline racemase family
FOB75_RS05845	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
FOB75_RS05850	COG1451	nucleotide metabolic process
FOB75_RS05855	COG3475	LICD family
FOB75_RS05860	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOB75_RS05865	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FOB75_RS05885	COG0583	DNA-binding transcription factor activity
FOB75_RS05905	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
FOB75_RS05910	COG4139	cobalamin transport
FOB75_RS05915	COG2988	succinylglutamate desuccinylase activity
FOB75_RS05930	COG2062	phosphohistidine phosphatase, SixA
FOB75_RS05940	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FOB75_RS05945	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FOB75_RS05950	COG0702	epimerase
FOB75_RS05955	COG1823	symporter activity
FOB75_RS05960	COG2925	Exonuclease
FOB75_RS05965	COG1380	Effector of murein hydrolase LrgA
FOB75_RS05970	COG1346	cytolysis
FOB75_RS05975	COG0295	cytidine deaminase activity
FOB75_RS05980	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
FOB75_RS05985	COG0500	methyltransferase
FOB75_RS05995	COG0776	regulation of translation
FOB75_RS06010	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOB75_RS06010	COG0072	phenylalanine-tRNA ligase activity
FOB75_RS06015	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FOB75_RS06020	COG3706	GGDEF domain
FOB75_RS06050	COG0393	Putative heavy-metal-binding
FOB75_RS06060	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FOB75_RS06070	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FOB75_RS06085	COG2188	Transcriptional regulator
FOB75_RS06090	COG1228	amidohydrolase
FOB75_RS06095	COG0010	Belongs to the arginase family
FOB75_RS06100	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FOB75_RS06105	COG2986	histidine ammonia-lyase
FOB75_RS06120	COG0277	FAD linked oxidase domain protein
FOB75_RS06120	COG0247	lactate metabolic process
FOB75_RS06155	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FOB75_RS06170	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
FOB75_RS06175	COG1643	Atp-dependent helicase
FOB75_RS06180	COG0281	malic enzyme
FOB75_RS06185	COG2949	membrane
FOB75_RS06190	COG0471	metal ion transport
FOB75_RS06215	COG0492	ferredoxin-NADP+ reductase activity
FOB75_RS06220	COG4988	ABC transporter
FOB75_RS06225	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FOB75_RS06230	COG3048	D-serine ammonia-lyase activity
FOB75_RS06235	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FOB75_RS06245	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOB75_RS06245	COG4191	Histidine kinase
FOB75_RS06260	COG3070	regulator of competence-specific genes
FOB75_RS06280	COG2431	L-lysine efflux transmembrane transporter activity
FOB75_RS06295	COG0076	glutamate decarboxylase activity
FOB75_RS06300	COG1737	Transcriptional regulator
FOB75_RS06315	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FOB75_RS06320	COG3273	potassium ion transport
FOB75_RS06320	COG2985	domain, Protein
FOB75_RS06325	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FOB75_RS06340	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FOB75_RS06355	COG4181	ATPase activity
FOB75_RS06360	COG0534	Mate efflux family protein
FOB75_RS06365	COG0702	epimerase
FOB75_RS06370	COG3005	denitrification pathway
FOB75_RS06400	COG2814	Major facilitator Superfamily
FOB75_RS06405	COG1187	pseudouridine synthase activity
FOB75_RS06410	COG1061	Type III restriction enzyme res subunit
FOB75_RS06430	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FOB75_RS06460	COG3313	Fe-S protein
FOB75_RS06485	COG0493	'glutamate synthase
FOB75_RS06495	COG0398	Pfam SNARE associated Golgi protein
FOB75_RS06500	COG4134	Bacterial extracellular solute-binding protein
FOB75_RS06505	COG4135	transport system, permease component
FOB75_RS06510	COG4136	ATPase activity
FOB75_RS06515	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FOB75_RS06530	COG3604	Transcriptional regulator
FOB75_RS06535	COG1151	hydroxylamine reductase activity
FOB75_RS06540	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FOB75_RS06550	COG0564	pseudouridine synthase activity
FOB75_RS06560	COG0733	neurotransmitter:sodium symporter activity
FOB75_RS06570	COG0626	cystathionine gamma-synthase activity
FOB75_RS06575	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
FOB75_RS06580	COG5380	lipid catabolic process
FOB75_RS06585	COG2818	Glycosylase
FOB75_RS06600	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOB75_RS06605	COG1983	PspC domain protein
FOB75_RS06615	COG1842	Phage shock protein A
FOB75_RS06620	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
FOB75_RS06635	COG4171	peptide transport system, permease
FOB75_RS06645	COG4172	Belongs to the ABC transporter superfamily
FOB75_RS06655	COG1227	inorganic diphosphatase activity
FOB75_RS06670	COG0243	molybdopterin cofactor binding
FOB75_RS06675	COG3005	denitrification pathway
FOB75_RS06680	COG4459	periplasmic nitrate reductase
FOB75_RS06685	COG0390	transport system, permease component
FOB75_RS06695	COG2116	formate transmembrane transporter activity
FOB75_RS06720	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FOB75_RS06725	COG1435	thymidine kinase activity
FOB75_RS06730	COG0215	cysteine-tRNA ligase activity
FOB75_RS06735	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FOB75_RS06740	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FOB75_RS06745	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FOB75_RS06755	COG3012	SEC-C Motif Domain Protein
FOB75_RS06760	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FOB75_RS06760	COG0140	phosphoribosyl-ATP diphosphatase activity
FOB75_RS06765	COG0107	imidazoleglycerol-phosphate synthase activity
FOB75_RS06770	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FOB75_RS06775	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FOB75_RS06780	COG0131	Imidazoleglycerol-phosphate dehydratase
FOB75_RS06780	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FOB75_RS06785	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FOB75_RS06790	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FOB75_RS06795	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FOB75_RS06810	COG1757	Na H antiporter
FOB75_RS06820	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOB75_RS06830	COG0482	sulfurtransferase activity
FOB75_RS06835	COG2915	High frequency lysogenization protein hflD homolog
FOB75_RS06840	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FOB75_RS06865	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FOB75_RS06880	COG0300	oxidoreductase activity
FOB75_RS06890	COG0501	Belongs to the peptidase M48B family
FOB75_RS06900	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FOB75_RS06910	COG0156	8-amino-7-oxononanoate synthase activity
FOB75_RS06915	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FOB75_RS06920	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FOB75_RS06925	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FOB75_RS06940	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FOB75_RS06945	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FOB75_RS06950	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FOB75_RS06955	COG1674	ftsk spoiiie
FOB75_RS06965	COG0686	Belongs to the AlaDH PNT family
FOB75_RS06975	COG0583	DNA-binding transcription factor activity
FOB75_RS06990	COG3568	Endonuclease Exonuclease Phosphatase
FOB75_RS07020	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOB75_RS07025	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOB75_RS07040	COG0840	transmembrane signaling receptor activity
FOB75_RS07070	COG5002	protein histidine kinase activity
FOB75_RS07070	COG0784	Response regulator, receiver
FOB75_RS07080	COG0754	glutathionylspermidine amidase activity
FOB75_RS07090	COG3766	membrane
FOB75_RS07100	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FOB75_RS07105	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
FOB75_RS07110	COG2885	chlorophyll binding
FOB75_RS07115	COG0823	Involved in the tonB-independent uptake of proteins
FOB75_RS07130	COG0811	peptide transport
FOB75_RS07135	COG0824	Thioesterase
FOB75_RS07145	COG4890	Cyd operon protein YbgT
FOB75_RS07150	COG1294	oxidase, subunit
FOB75_RS07155	COG1271	oxidase subunit
FOB75_RS07160	COG2255	four-way junction helicase activity
FOB75_RS07165	COG0632	four-way junction helicase activity
FOB75_RS07170	COG0840	transmembrane signaling receptor activity
FOB75_RS07175	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FOB75_RS07180	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FOB75_RS07185	COG1801	Protein of unknown function DUF72
FOB75_RS07190	COG4106	trans-aconitate 2-methyltransferase activity
FOB75_RS07195	COG0500	methyltransferase
FOB75_RS07205	COG4067	protein conserved in archaea
FOB75_RS07205	COG0189	ligase activity
FOB75_RS07225	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FOB75_RS07230	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
FOB75_RS07235	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
FOB75_RS07240	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FOB75_RS07245	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FOB75_RS07250	COG0745	RESPONSE REGULATOR receiver
FOB75_RS07255	COG3381	protein complex oligomerization
FOB75_RS07260	COG1609	Transcriptional regulator
FOB75_RS07265	COG3070	regulator of competence-specific genes
FOB75_RS07285	COG0297	glycogen (starch) synthase activity
FOB75_RS07290	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FOB75_RS07295	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FOB75_RS07305	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FOB75_RS07315	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FOB75_RS07320	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FOB75_RS07325	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FOB75_RS07335	COG0542	response to heat
FOB75_RS07340	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FOB75_RS07345	COG1278	Cold shock
FOB75_RS07355	COG1187	pseudouridine synthase activity
FOB75_RS07360	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
FOB75_RS07365	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FOB75_RS07370	COG1199	ATP-dependent helicase activity
FOB75_RS07375	COG0730	response to heat
FOB75_RS07380	COG3923	Primosomal replication protein n
FOB75_RS07390	COG0708	Exodeoxyribonuclease III
FOB75_RS07435	COG1882	Formate acetyltransferase
FOB75_RS07445	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FOB75_RS07455	COG3013	Belongs to the UPF0304 family
FOB75_RS07465	COG2766	serine protein kinase
FOB75_RS07470	COG2718	Belongs to the UPF0229 family
FOB75_RS07475	COG2719	SpoVR family
FOB75_RS07480	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FOB75_RS07490	COG1663	tetraacyldisaccharide 4'-kinase activity
FOB75_RS07495	COG1132	(ABC) transporter
FOB75_RS07500	COG0658	competence protein
FOB75_RS07500	COG2333	competence protein COMEC
FOB75_RS07510	COG4591	ABC-type transport system involved in lipoprotein release permease component
FOB75_RS07515	COG1136	(ABC) transporter
FOB75_RS07520	COG4591	ABC-type transport system involved in lipoprotein release permease component
FOB75_RS07530	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FOB75_RS07545	COG1252	NADH dehydrogenase
FOB75_RS07560	COG3150	esterase
FOB75_RS07585	COG0537	adenosine 5'-monophosphoramidase activity
FOB75_RS07615	COG0517	IMP dehydrogenase activity
FOB75_RS07615	COG0516	GMP reductase activity
FOB75_RS07625	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
FOB75_RS07630	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FOB75_RS07635	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FOB75_RS07645	COG2199	diguanylate cyclase activity
FOB75_RS07660	COG3126	Type III secretion system lipoprotein chaperone (YscW)
FOB75_RS07665	COG1946	Acyl-CoA thioesterase
FOB75_RS07675	COG1522	sequence-specific DNA binding
FOB75_RS07705	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOB75_RS07755	COG0477	Major facilitator Superfamily
FOB75_RS07760	COG2855	membrane
FOB75_RS07780	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FOB75_RS07785	COG0596	Alpha beta hydrolase
FOB75_RS07790	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
FOB75_RS07795	COG1169	isochorismate synthase
FOB75_RS07800	COG0436	Aminotransferase
FOB75_RS07805	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
FOB75_RS07810	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FOB75_RS07825	COG1555	photosystem II stabilization
FOB75_RS07830	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FOB75_RS07835	COG0776	regulation of translation
FOB75_RS07840	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FOB75_RS07845	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FOB75_RS07855	COG0544	peptidyl-prolyl cis-trans isomerase activity
FOB75_RS07865	COG2204	response regulator
FOB75_RS07875	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FOB75_RS07880	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FOB75_RS07885	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FOB75_RS07890	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FOB75_RS07910	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FOB75_RS07915	COG0569	domain protein
FOB75_RS07920	COG0513	Belongs to the DEAD box helicase family
FOB75_RS07925	COG1253	flavin adenine dinucleotide binding
FOB75_RS07960	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FOB75_RS07965	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FOB75_RS07980	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FOB75_RS07985	COG1216	Glycosyl transferase, family 2
FOB75_RS07990	COG2986	histidine ammonia-lyase
FOB75_RS08015	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FOB75_RS08025	COG1028	Short-chain dehydrogenase reductase Sdr
FOB75_RS08045	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FOB75_RS08050	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOB75_RS08055	COG0583	DNA-binding transcription factor activity
FOB75_RS08060	COG2951	lytic endotransglycosylase activity
FOB75_RS08065	COG3100	YcgL domain-containing protein
FOB75_RS08070	COG0850	regulation of cytokinetic process
FOB75_RS08075	COG2894	cell division
FOB75_RS08080	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FOB75_RS08085	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FOB75_RS08090	COG0318	PFAM AMP-dependent synthetase and ligase
FOB75_RS08095	COG2267	carboxylic ester hydrolase activity
FOB75_RS08110	COG1214	PFAM Peptidase M22, glycoprotease
FOB75_RS08115	COG1199	ATP-dependent helicase activity
FOB75_RS08120	COG0788	formyltetrahydrofolate deformylase activity
FOB75_RS08125	COG3102	Protein conserved in bacteria
FOB75_RS08135	COG0018	arginyl-trna synthetase
FOB75_RS08155	COG1918	ferrous iron import across plasma membrane
FOB75_RS08170	COG4977	sequence-specific DNA binding
FOB75_RS08175	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
FOB75_RS08180	COG1121	(ABC) transporter
FOB75_RS08185	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FOB75_RS08200	COG0045	succinate-CoA ligase (ADP-forming) activity
FOB75_RS08205	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOB75_RS08210	COG0567	Dehydrogenase, E1 component
FOB75_RS08215	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FOB75_RS08220	COG1053	succinate dehydrogenase
FOB75_RS08225	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FOB75_RS08240	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FOB75_RS08250	COG0033	Phosphoglucomutase
FOB75_RS08255	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
FOB75_RS08260	COG0596	Alpha beta hydrolase
FOB75_RS08280	COG0735	belongs to the Fur family
FOB75_RS08285	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FOB75_RS08290	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOB75_RS08290	COG1263	PTS System
FOB75_RS08300	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FOB75_RS08305	COG1940	carbohydrate kinase activity
FOB75_RS08305	COG1846	Transcriptional regulator
FOB75_RS08310	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FOB75_RS08310	COG4651	solute:proton antiporter activity
FOB75_RS08315	COG0367	asparagine synthase
FOB75_RS08320	COG0250	Participates in transcription elongation, termination and antitermination
FOB75_RS08325	COG3104	oligopeptide transport
FOB75_RS08330	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FOB75_RS08335	COG0563	adenylate kinase activity
FOB75_RS08340	COG0326	Molecular chaperone. Has ATPase activity
FOB75_RS08345	COG3710	Transcriptional regulator
FOB75_RS08365	COG0622	Phosphoesterase
FOB75_RS08395	COG1090	epimerase
FOB75_RS08400	COG0300	oxidoreductase activity
FOB75_RS08410	COG3118	belongs to the thioredoxin family
FOB75_RS08415	COG3118	belongs to the thioredoxin family
FOB75_RS08415	COG0457	Tetratricopeptide repeat
FOB75_RS08420	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
FOB75_RS08425	COG1215	transferase activity, transferring glycosyl groups
FOB75_RS08430	COG1215	transferase activity, transferring glycosyl groups
FOB75_RS08450	COG2194	sulfuric ester hydrolase activity
FOB75_RS08455	COG0330	HflC and HflK could
FOB75_RS08480	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FOB75_RS08485	COG3115	cell septum assembly
FOB75_RS08490	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
FOB75_RS08495	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FOB75_RS08505	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOB75_RS08510	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FOB75_RS08515	COG2190	(PTS) system
FOB75_RS08525	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FOB75_RS08530	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FOB75_RS08540	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FOB75_RS08550	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FOB75_RS08560	COG1705	Flagellar rod assembly protein muramidase FlgJ
FOB75_RS08560	COG3951	Flagellar rod assembly protein muramidase FlgJ
FOB75_RS08565	COG1706	bacterial-type flagellum-dependent cell motility
FOB75_RS08570	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FOB75_RS08580	COG4787	bacterial-type flagellum-dependent cell motility
FOB75_RS08590	COG1749	Flagellar hook protein flgE
FOB75_RS08600	COG1558	bacterial-type flagellum-dependent cell motility
FOB75_RS08605	COG1815	bacterial-type flagellum-dependent cell motility
FOB75_RS08610	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FOB75_RS08615	COG0784	Response regulator, receiver
FOB75_RS08615	COG0835	chemotaxis
FOB75_RS08675	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FOB75_RS08680	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
FOB75_RS08695	COG2217	Heavy metal translocating P-type atpase
FOB75_RS08695	COG2608	mercury ion transmembrane transporter activity
FOB75_RS08735	COG2840	Smr protein MutS2
FOB75_RS08740	COG1187	pseudouridine synthase activity
FOB75_RS08750	COG0737	Belongs to the 5'-nucleotidase family
FOB75_RS08755	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FOB75_RS08760	COG2912	Transglutaminase-like superfamily
FOB75_RS08765	COG3094	Invasion gene expression up-regulator, SirB
FOB75_RS08770	COG2890	protein-(glutamine-N5) methyltransferase activity
FOB75_RS08775	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FOB75_RS08780	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FOB75_RS08785	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
FOB75_RS08790	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FOB75_RS08795	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FOB75_RS08800	COG0193	aminoacyl-tRNA hydrolase activity
FOB75_RS08805	COG0012	GTP binding
FOB75_RS08920	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FOB75_RS08930	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FOB75_RS08935	COG1702	phosphate starvation-inducible protein PhoH
FOB75_RS08940	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FOB75_RS08945	COG4535	Mg2 and Co2 transporter CorC
FOB75_RS08950	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FOB75_RS08955	COG2888	peptidyl-tyrosine sulfation
FOB75_RS08960	COG0495	leucyl-tRNA aminoacylation
FOB75_RS08965	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
FOB75_RS08970	COG1466	dna polymerase III delta subunit
FOB75_RS08975	COG0799	negative regulation of ribosome biogenesis
FOB75_RS08980	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FOB75_RS08985	COG0768	penicillin binding
FOB75_RS08990	COG0772	Belongs to the SEDS family
FOB75_RS08995	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FOB75_RS09000	COG1686	Belongs to the peptidase S11 family
FOB75_RS09005	COG2921	Belongs to the UPF0250 family
FOB75_RS09010	COG0321	lipoyl(octanoyl) transferase activity
FOB75_RS09015	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FOB75_RS09020	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FOB75_RS09025	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOB75_RS09035	COG0366	Alpha amylase catalytic
FOB75_RS09040	COG1263	PTS System
FOB75_RS09040	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOB75_RS09050	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FOB75_RS09060	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FOB75_RS09065	COG2011	ABC-type metal ion transport system permease component
FOB75_RS09070	COG1464	Belongs to the NlpA lipoprotein family
FOB75_RS09075	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
FOB75_RS09085	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FOB75_RS09085	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FOB75_RS09100	COG1611	Belongs to the LOG family
FOB75_RS09105	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOB75_RS09115	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
FOB75_RS09120	COG2363	Small membrane protein
FOB75_RS09130	COG0583	DNA-binding transcription factor activity
FOB75_RS09135	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOB75_RS09135	COG0301	tRNA thio-modification
FOB75_RS09140	COG2885	chlorophyll binding
FOB75_RS09145	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FOB75_RS09150	COG1722	exodeoxyribonuclease VII activity
FOB75_RS09155	COG0142	geranyltranstransferase activity
FOB75_RS09160	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FOB75_RS09165	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FOB75_RS09170	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FOB75_RS09175	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FOB75_RS09195	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FOB75_RS09195	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FOB75_RS09200	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FOB75_RS09205	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FOB75_RS09210	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FOB75_RS09220	COG1073	alpha beta
FOB75_RS09225	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
FOB75_RS09230	COG2252	PERMEase
FOB75_RS09235	COG2195	Cleaves the N-terminal amino acid of tripeptides
FOB75_RS09260	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FOB75_RS09260	COG0047	phosphoribosylformylglycinamidine synthase activity
FOB75_RS09265	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FOB75_RS09285	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
FOB75_RS09325	COG0484	heat shock protein binding
FOB75_RS09330	COG0443	Heat shock 70 kDa protein
FOB75_RS09340	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FOB75_RS09345	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FOB75_RS09355	COG0497	DNA recombination
FOB75_RS09360	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FOB75_RS09365	COG2914	Belongs to the UPF0125 (RnfH) family
FOB75_RS09370	COG2867	negative regulation of translational initiation
FOB75_RS09375	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FOB75_RS09430	COG0583	DNA-binding transcription factor activity
FOB75_RS09435	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FOB75_RS09435	COG3153	acetyltransferase
FOB75_RS09455	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FOB75_RS09460	COG2873	o-acetylhomoserine
FOB75_RS09500	COG1115	amino acid carrier protein
FOB75_RS09510	COG1584	GPR1 FUN34 yaaH family protein
FOB75_RS09520	COG1757	Na H antiporter
FOB75_RS09525	COG0519	Catalyzes the synthesis of GMP from XMP
FOB75_RS09525	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FOB75_RS09530	COG0517	IMP dehydrogenase activity
FOB75_RS09530	COG0516	GMP reductase activity
FOB75_RS09535	COG1570	exodeoxyribonuclease VII activity
FOB75_RS09550	COG1160	GTP binding
FOB75_RS09555	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FOB75_RS09560	COG2976	Protein conserved in bacteria
FOB75_RS09565	COG0124	histidyl-tRNA synthetase
FOB75_RS09570	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FOB75_RS09585	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FOB75_RS09590	COG0105	UTP biosynthetic process
FOB75_RS09595	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FOB75_RS09600	COG2975	iron-sulfur cluster assembly
FOB75_RS09605	COG0633	Ferredoxin
FOB75_RS09610	COG0443	Heat shock 70 kDa protein
FOB75_RS09615	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FOB75_RS09625	COG0822	iron-sulfur transferase activity
FOB75_RS09630	COG1104	cysteine desulfurase activity
FOB75_RS09635	COG1959	2 iron, 2 sulfur cluster binding
FOB75_RS09645	COG0483	inositol monophosphate 1-phosphatase activity
FOB75_RS09655	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FOB75_RS09660	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FOB75_RS09665	COG1862	Preprotein translocase
FOB75_RS09670	COG0343	queuine tRNA-ribosyltransferase activity
FOB75_RS09675	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FOB75_RS09690	COG0517	IMP dehydrogenase activity
FOB75_RS09700	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FOB75_RS09710	COG0583	DNA-binding transcription factor activity
FOB75_RS09715	COG0450	alkyl hydroperoxide reductase
FOB75_RS09725	COG3142	Participates in the control of copper homeostasis
FOB75_RS09735	COG0704	Plays a role in the regulation of phosphate uptake
FOB75_RS09740	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FOB75_RS09745	COG0581	inorganic phosphate transmembrane transporter activity
FOB75_RS09755	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FOB75_RS09760	COG0248	Ppx GppA phosphatase
FOB75_RS09770	COG5002	protein histidine kinase activity
FOB75_RS09775	COG0745	RESPONSE REGULATOR receiver
FOB75_RS09785	COG2974	May be involved in recombination
FOB75_RS09790	COG0826	peptidase U32
FOB75_RS09795	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FOB75_RS09855	COG0542	response to heat
FOB75_RS09865	COG0564	pseudouridine synthase activity
FOB75_RS09870	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FOB75_RS09875	COG0741	lytic transglycosylase activity
FOB75_RS09880	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FOB75_RS09885	COG0077	Prephenate dehydratase
FOB75_RS09885	COG1605	Chorismate mutase
FOB75_RS09890	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
FOB75_RS09895	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
FOB75_RS09905	COG0488	(ABC) transporter
FOB75_RS09920	COG0739	heme binding
FOB75_RS09925	COG0287	Prephenate dehydrogenase
FOB75_RS09925	COG1605	Chorismate mutase
FOB75_RS09930	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FOB75_RS09935	COG1472	Belongs to the glycosyl hydrolase 3 family
FOB75_RS09940	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FOB75_RS09945	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FOB75_RS09960	COG1966	Carbon starvation protein
FOB75_RS09965	COG3275	phosphorelay sensor kinase activity
FOB75_RS09970	COG3279	Response regulator of the LytR AlgR family
FOB75_RS09975	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FOB75_RS09980	COG1047	Peptidyl-prolyl cis-trans
FOB75_RS09985	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FOB75_RS09990	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FOB75_RS09995	COG0196	riboflavin kinase activity
FOB75_RS10000	COG0728	peptidoglycan biosynthetic process
FOB75_RS10005	COG0268	Binds directly to 16S ribosomal RNA
FOB75_RS10015	COG0640	Transcriptional regulator
FOB75_RS10025	COG0583	DNA-binding transcription factor activity
FOB75_RS10030	COG1283	sodium-dependent phosphate transmembrane transporter activity
FOB75_RS10040	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FOB75_RS10045	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FOB75_RS10050	COG0730	response to heat
FOB75_RS10060	COG0494	nUDIX hydrolase
FOB75_RS10070	COG3066	DNA modification
FOB75_RS10080	COG0667	Aldo Keto reductase
FOB75_RS10095	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FOB75_RS10105	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FOB75_RS10110	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FOB75_RS10115	COG4974	Belongs to the 'phage' integrase family
FOB75_RS10120	COG0716	FMN binding
FOB75_RS10130	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FOB75_RS10135	COG0513	Belongs to the DEAD box helicase family
FOB75_RS10140	COG3022	response to hydroperoxide
FOB75_RS10145	COG1115	amino acid carrier protein
FOB75_RS10160	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FOB75_RS10170	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
FOB75_RS10175	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
FOB75_RS10185	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FOB75_RS10190	COG0083	homoserine kinase activity
FOB75_RS10205	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FOB75_RS10220	COG0745	RESPONSE REGULATOR receiver
FOB75_RS10230	COG5002	protein histidine kinase activity
FOB75_RS10230	COG2198	Histidine kinase
FOB75_RS10230	COG0784	Response regulator, receiver
FOB75_RS10235	COG4251	negative regulation of phosphorylation
FOB75_RS10235	COG3706	GGDEF domain
FOB75_RS10235	COG5001	Diguanylate cyclase
FOB75_RS10235	COG2203	Gaf domain
FOB75_RS10240	COG1242	4 iron, 4 sulfur cluster binding
FOB75_RS10245	COG0067	glutamate synthase
FOB75_RS10245	COG0070	glutamate synthase
FOB75_RS10245	COG0069	glutamate synthase activity
FOB75_RS10255	COG0067	glutamate synthase
FOB75_RS10255	COG0069	glutamate synthase activity
FOB75_RS10255	COG0070	glutamate synthase
FOB75_RS10260	COG0493	'glutamate synthase
FOB75_RS10270	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FOB75_RS10280	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOB75_RS10285	COG2860	membrane
FOB75_RS10290	COG0583	DNA-binding transcription factor activity
FOB75_RS10295	COG0730	response to heat
FOB75_RS10310	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FOB75_RS10315	COG0505	Belongs to the CarA family
FOB75_RS10320	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FOB75_RS10325	COG0494	nUDIX hydrolase
FOB75_RS10330	COG0653	protein targeting
FOB75_RS10340	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
FOB75_RS10345	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FOB75_RS10350	COG0849	cell division
FOB75_RS10355	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FOB75_RS10360	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FOB75_RS10365	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FOB75_RS10370	COG0772	Belongs to the SEDS family
FOB75_RS10375	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FOB75_RS10380	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FOB75_RS10385	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FOB75_RS10390	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FOB75_RS10395	COG0768	penicillin binding
FOB75_RS10400	COG3116	cell division
FOB75_RS10405	COG0275	rRNA processing
FOB75_RS10420	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FOB75_RS10430	COG0792	nuclease activity
FOB75_RS10435	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FOB75_RS10440	COG2823	Periplasmic or secreted lipoprotein
FOB75_RS10445	COG2969	positive regulation of protein catabolic process
FOB75_RS10450	COG0625	glutathione transferase activity
FOB75_RS10455	COG2857	Cytochrome c1
FOB75_RS10460	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FOB75_RS10465	COG0723	plastoquinol--plastocyanin reductase activity
FOB75_RS10470	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FOB75_RS10475	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FOB75_RS10485	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FOB75_RS10495	COG3105	Protein conserved in bacteria
FOB75_RS10505	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOB75_RS10510	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FOB75_RS10520	COG3150	esterase
FOB75_RS10530	COG3151	Protein conserved in bacteria
FOB75_RS10535	COG0494	nUDIX hydrolase
FOB75_RS10540	COG1538	Outer membrane efflux protein
FOB75_RS10545	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FOB75_RS10545	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FOB75_RS10550	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FOB75_RS10565	COG3025	triphosphatase activity
FOB75_RS10570	COG1392	Phosphate transport regulator
FOB75_RS10575	COG0306	phosphate transporter
FOB75_RS10580	COG4991	sh3 domain protein
FOB75_RS10590	COG3409	Peptidoglycan-binding domain 1 protein
FOB75_RS10590	COG3267	Type II secretory pathway component ExeA
FOB75_RS10595	COG0617	tRNA 3'-terminal CCA addition
FOB75_RS10600	COG1968	undecaprenyl-diphosphatase activity
FOB75_RS10605	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FOB75_RS10610	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FOB75_RS10615	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FOB75_RS10620	COG0596	Alpha beta hydrolase
FOB75_RS10625	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FOB75_RS10630	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FOB75_RS10635	COG1610	YqeY-like protein
FOB75_RS10640	COG0358	DNA primase activity
FOB75_RS10655	COG1464	Belongs to the NlpA lipoprotein family
FOB75_RS10690	COG2213	PTS system mannitol-specific
FOB75_RS10690	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOB75_RS10695	COG0246	Mannitol dehydrogenase
FOB75_RS10700	COG3722	fumarate hydratase activity
FOB75_RS10715	COG1461	Dihydroxyacetone kinase
FOB75_RS10720	COG2376	Dihydroxyacetone kinase
FOB75_RS10730	COG5002	protein histidine kinase activity
FOB75_RS10745	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FOB75_RS10750	COG1349	DNA-binding transcription factor activity
FOB75_RS10760	COG0469	pyruvate kinase activity
FOB75_RS10775	COG0440	acetolactate synthase activity
FOB75_RS10780	COG0028	Belongs to the TPP enzyme family
FOB75_RS10785	COG1022	Amp-dependent synthetase and ligase
FOB75_RS10790	COG0583	DNA-binding transcription factor activity
FOB75_RS10810	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FOB75_RS10815	COG0473	3-isopropylmalate dehydrogenase activity
FOB75_RS10820	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FOB75_RS10825	COG0066	3-isopropylmalate dehydratase activity
FOB75_RS10835	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FOB75_RS10840	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FOB75_RS10845	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FOB75_RS10850	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FOB75_RS10855	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FOB75_RS10860	COG2967	ApaG domain
FOB75_RS10865	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FOB75_RS10880	COG2966	Psort location CytoplasmicMembrane, score
FOB75_RS10885	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FOB75_RS10895	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FOB75_RS10900	COG0142	geranyltranstransferase activity
FOB75_RS10910	COG0039	L-malate dehydrogenase activity
FOB75_RS10925	COG2358	TRAP transporter, solute receptor (TAXI family
FOB75_RS10945	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FOB75_RS10950	COG1178	ABC-type Fe3 transport system permease component
FOB75_RS10955	COG4143	(ABC) transporter
FOB75_RS10960	COG0163	prenyltransferase activity
FOB75_RS10965	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FOB75_RS10975	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
FOB75_RS10980	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FOB75_RS10990	COG2105	PFAM AIG2 family protein
FOB75_RS11000	COG0729	surface antigen
FOB75_RS11005	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FOB75_RS11015	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
FOB75_RS11030	COG4181	ATPase activity
FOB75_RS11050	COG0529	Catalyzes the synthesis of activated sulfate
FOB75_RS11055	COG3273	potassium ion transport
FOB75_RS11055	COG0471	metal ion transport
FOB75_RS11065	COG2895	sulfate adenylyltransferase (ATP) activity
FOB75_RS11070	COG0175	sulfate reduction
FOB75_RS11075	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FOB75_RS11075	COG1648	precorrin-2 dehydrogenase activity
FOB75_RS11080	COG0737	Belongs to the 5'-nucleotidase family
FOB75_RS11090	COG0513	Belongs to the DEAD box helicase family
FOB75_RS11095	COG2153	protein acetylation
FOB75_RS11105	COG0545	Peptidyl-prolyl cis-trans isomerase
FOB75_RS11115	COG0203	ribosomal protein L17
FOB75_RS11120	COG0202	RNA polymerase activity
FOB75_RS11130	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FOB75_RS11135	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FOB75_RS11140	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FOB75_RS11145	COG0201	protein transport
FOB75_RS11150	COG0200	Binds to the 23S rRNA
FOB75_RS11155	COG1841	ribosomal large subunit assembly
FOB75_RS11170	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FOB75_RS11175	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FOB75_RS11180	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FOB75_RS11185	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FOB75_RS11190	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FOB75_RS11195	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FOB75_RS11200	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FOB75_RS11205	COG0255	Belongs to the universal ribosomal protein uL29 family
FOB75_RS11215	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FOB75_RS11220	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FOB75_RS11225	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FOB75_RS11230	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FOB75_RS11240	COG0088	Forms part of the polypeptide exit tunnel
FOB75_RS11245	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FOB75_RS11255	COG0254	rRNA binding
FOB75_RS11265	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FOB75_RS11270	COG1609	Transcriptional regulator
FOB75_RS11280	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FOB75_RS11285	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FOB75_RS11290	COG1575	Belongs to the MenA family. Type 1 subfamily
FOB75_RS11295	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FOB75_RS11300	COG3074	FtsZ-dependent cytokinesis
FOB75_RS11310	COG1494	fructose-1,6-bisphosphatase
FOB75_RS11335	COG0149	triose-phosphate isomerase activity
FOB75_RS11340	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FOB75_RS11355	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FOB75_RS11380	COG1086	Polysaccharide biosynthesis protein
FOB75_RS11445	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FOB75_RS11455	COG1560	Kdo2-lipid A biosynthetic process
FOB75_RS11460	COG0859	PFAM glycosyl transferase family 9
FOB75_RS11465	COG1519	Transferase
FOB75_RS11475	COG1083	cytidylyl-transferase
FOB75_RS11480	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FOB75_RS11490	COG2089	acid synthase
FOB75_RS11495	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FOB75_RS11500	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FOB75_RS11515	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FOB75_RS11535	COG3642	lipopolysaccharide core region biosynthetic process
FOB75_RS11540	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FOB75_RS11545	COG0859	PFAM glycosyl transferase family 9
FOB75_RS11550	COG0463	Glycosyl transferase, family 2
FOB75_RS11575	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FOB75_RS11590	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FOB75_RS11595	COG2003	Belongs to the UPF0758 family
FOB75_RS11610	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FOB75_RS11615	COG1309	transcriptional regulator
FOB75_RS11620	COG1560	Kdo2-lipid A biosynthetic process
FOB75_RS11625	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FOB75_RS11630	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FOB75_RS11635	COG1561	YicC-like family, N-terminal region
FOB75_RS11645	COG4608	Belongs to the ABC transporter superfamily
FOB75_RS11650	COG0444	Belongs to the ABC transporter superfamily
FOB75_RS11655	COG0747	negative chemotaxis
FOB75_RS11660	COG4239	(ABC) transporter, permease
FOB75_RS11665	COG4174	ABC transporter (Permease)
FOB75_RS11690	COG0811	peptide transport
FOB75_RS11695	COG0848	biopolymer transport protein
FOB75_RS11710	COG0194	GDP metabolic process
FOB75_RS11715	COG1758	RNA polymerase activity
FOB75_RS11720	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FOB75_RS11725	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FOB75_RS11730	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FOB75_RS11740	COG2233	PERMEase
FOB75_RS11760	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FOB75_RS11770	COG2183	response to ionizing radiation
FOB75_RS11780	COG0596	Alpha beta hydrolase
FOB75_RS11785	COG1040	competence protein
FOB75_RS11790	COG0316	Belongs to the HesB IscA family
FOB75_RS11790	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FOB75_RS11795	COG0494	nUDIX hydrolase
FOB75_RS11800	COG1218	3'(2'),5'-bisphosphate nucleotidase
FOB75_RS11810	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
FOB75_RS11815	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
FOB75_RS11820	COG3156	type II secretion system protein K
FOB75_RS11825	COG4795	General secretion pathway protein
FOB75_RS11830	COG2165	general secretion pathway protein
FOB75_RS11835	COG2165	general secretion pathway protein
FOB75_RS11840	COG2165	general secretion pathway protein
FOB75_RS11845	COG1459	type II secretion system
FOB75_RS11850	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FOB75_RS11860	COG3031	protein transport across the cell outer membrane
FOB75_RS11865	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FOB75_RS11870	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FOB75_RS11875	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FOB75_RS11885	COG0456	acetyltransferase
FOB75_RS11890	COG1490	D-aminoacyl-tRNA deacylase activity
FOB75_RS11895	COG1295	ribonuclease BN
FOB75_RS11910	COG1217	gtp-binding protein TYPA
FOB75_RS11915	COG0174	glutamine synthetase
FOB75_RS11925	COG3852	Histidine kinase
FOB75_RS11930	COG2204	response regulator
FOB75_RS11940	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FOB75_RS11975	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FOB75_RS11985	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOB75_RS11985	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOB75_RS12010	COG0084	hydrolase, TatD family'
FOB75_RS12020	COG0805	protein transport
FOB75_RS12025	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FOB75_RS12030	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FOB75_RS12035	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FOB75_RS12040	COG3165	ubiquinone biosynthetic process from chorismate
FOB75_RS12045	COG2226	methyltransferase
FOB75_RS12050	COG1322	Protein conserved in bacteria
FOB75_RS12065	COG0628	permease
FOB75_RS12115	COG2823	Periplasmic or secreted lipoprotein
FOB75_RS12125	COG2081	HI0933 family
FOB75_RS12135	COG1528	Iron-storage protein
FOB75_RS12140	COG0589	response to stress
FOB75_RS12155	COG0742	ribosomal rna small subunit methyltransferase
FOB75_RS12160	COG5002	protein histidine kinase activity
FOB75_RS12160	COG5001	Diguanylate cyclase
FOB75_RS12165	COG1522	sequence-specific DNA binding
FOB75_RS12170	COG0339	signal peptide processing
FOB75_RS12180	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FOB75_RS12185	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOB75_RS12190	COG0583	DNA-binding transcription factor activity
FOB75_RS12195	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FOB75_RS12200	COG0800	Aldolase
FOB75_RS12205	COG2610	gluconate transmembrane transporter activity
FOB75_RS12210	COG3265	gluconokinase activity
FOB75_RS12215	COG0129	dihydroxy-acid dehydratase activity
FOB75_RS12230	COG0583	DNA-binding transcription factor activity
FOB75_RS12235	COG1609	Transcriptional regulator
FOB75_RS12275	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOB75_RS12280	COG0601	transmembrane transport
FOB75_RS12285	COG0747	negative chemotaxis
FOB75_RS12290	COG4172	Belongs to the ABC transporter superfamily
FOB75_RS12355	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOB75_RS12360	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOB75_RS12370	COG2960	long-chain fatty acid transporting porin activity
FOB75_RS12375	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FOB75_RS12380	COG0583	DNA-binding transcription factor activity
FOB75_RS12425	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FOB75_RS12435	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FOB75_RS12440	COG0408	coproporphyrinogen oxidase activity
FOB75_RS12445	COG0009	L-threonylcarbamoyladenylate synthase
FOB75_RS12450	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FOB75_RS12455	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FOB75_RS12460	COG0551	DNA topoisomerase type I activity
FOB75_RS12465	COG2922	Belongs to the Smg family
FOB75_RS12470	COG0758	DNA mediated transformation
FOB75_RS12480	COG0242	peptide deformylase activity
FOB75_RS12485	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FOB75_RS12490	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FOB75_RS12490	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FOB75_RS12495	COG0569	domain protein
FOB75_RS12500	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FOB75_RS12510	COG1272	protein, Hemolysin III
FOB75_RS12515	COG4326	sporulation control protein
FOB75_RS12525	COG3084	Protein conserved in bacteria
FOB75_RS12535	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FOB75_RS12540	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FOB75_RS12545	COG0204	Acyl-transferase
FOB75_RS12555	COG0606	chelatase, subunit chli
FOB75_RS12565	COG3978	acetolactate synthase activity
FOB75_RS12570	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FOB75_RS12575	COG0129	dihydroxy-acid dehydratase activity
FOB75_RS12585	COG0583	DNA-binding transcription factor activity
FOB75_RS12590	COG2814	Major facilitator Superfamily
FOB75_RS12595	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOB75_RS12600	COG0765	amino acid transport
FOB75_RS12605	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FOB75_RS12610	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FOB75_RS12615	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FOB75_RS12620	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FOB75_RS12625	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FOB75_RS12630	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FOB75_RS12645	COG0356	it plays a direct role in the translocation of protons across the membrane
FOB75_RS12650	COG3312	ion transport
FOB75_RS12655	COG1475	DNA binding
FOB75_RS12660	COG1192	Involved in chromosome partitioning
FOB75_RS12665	COG0357	Ribosomal RNA small subunit methyltransferase G
FOB75_RS12670	COG0445	tRNA wobble uridine modification
FOB75_RS12675	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FOB75_RS12680	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FOB75_RS12685	COG0706	membrane insertase activity
FOB75_RS12695	COG0594	ribonuclease P activity
FOB75_RS12705	COG1126	abc transporter atp-binding protein
FOB75_RS12730	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FOB75_RS12735	COG0592	DNA-directed DNA polymerase activity
FOB75_RS12740	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FOB75_RS12745	COG0187	DNA topoisomerase II activity
FOB75_RS12765	COG0071	Belongs to the small heat shock protein (HSP20) family
FOB75_RS12770	COG3977	Valine--pyruvate aminotransferase
FOB75_RS12775	COG0366	Alpha amylase catalytic
FOB75_RS12780	COG0751	glycine-tRNA ligase activity
FOB75_RS12785	COG0752	glycyl-tRNA synthetase alpha subunit
FOB75_RS12790	COG2119	membrane
FOB75_RS12800	COG0425	Belongs to the sulfur carrier protein TusA family
FOB75_RS12815	COG0604	alcohol dehydrogenase
FOB75_RS12820	COG0183	Belongs to the thiolase family
FOB75_RS12825	COG1024	Enoyl-CoA hydratase
FOB75_RS12825	COG1250	3-hydroxyacyl-CoA dehydrogenase
FOB75_RS12830	COG1739	Uncharacterized protein family UPF0029
FOB75_RS12835	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FOB75_RS12905	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FOB75_RS12910	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FOB75_RS12920	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FOB75_RS12925	COG2104	thiamine diphosphate biosynthetic process
FOB75_RS12930	COG2022	thiamine diphosphate biosynthetic process
FOB75_RS12940	COG0006	proline dipeptidase activity
FOB75_RS12940	COG0006	proline dipeptidase activity
FOB75_RS12970	COG3220	belongs to the UPF0276 family
FOB75_RS12980	COG0210	DNA helicase
FOB75_RS12990	COG0405	Gamma-glutamyltransferase
FOB75_RS12995	COG1280	lysine exporter protein (LysE YggA)
FOB75_RS13005	COG2962	Rard protein
FOB75_RS13010	COG0514	ATP-dependent DNA helicase (RecQ)
FOB75_RS13025	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FOB75_RS13030	COG0248	Ppx GppA phosphatase
FOB75_RS13035	COG0513	Belongs to the DEAD box helicase family
FOB75_RS13040	COG3118	belongs to the thioredoxin family
FOB75_RS13060	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FOB75_RS13065	COG0633	Ferredoxin
FOB75_RS13115	COG3071	HemY protein
FOB75_RS13120	COG2959	enzyme of heme biosynthesis
FOB75_RS13125	COG1587	Uroporphyrinogen-III synthase
FOB75_RS13130	COG0181	hydroxymethylbilane synthase activity
FOB75_RS13135	COG3072	Adenylate cyclase
FOB75_RS13140	COG1965	Belongs to the frataxin family
FOB75_RS13150	COG0019	diaminopimelate decarboxylase activity
FOB75_RS13155	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FOB75_RS13165	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FOB75_RS13170	COG1011	Hydrolase
FOB75_RS13175	COG3287	FIST C domain
FOB75_RS13175	COG2200	EAL domain
FOB75_RS13175	COG2199	diguanylate cyclase activity
FOB75_RS13180	COG3148	PFAM DTW domain containing protein
FOB75_RS13195	COG0561	phosphatase activity
FOB75_RS13205	COG2267	carboxylic ester hydrolase activity
FOB75_RS13210	COG1280	lysine exporter protein (LysE YggA)
FOB75_RS13215	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FOB75_RS13220	COG0640	Transcriptional regulator
FOB75_RS13225	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FOB75_RS13280	COG2095	MarC family integral membrane protein
FOB75_RS13290	COG0742	ribosomal rna small subunit methyltransferase
FOB75_RS13295	COG0552	protein localization to endoplasmic reticulum
FOB75_RS13300	COG2884	Cell division ATP-binding protein ftsE
FOB75_RS13305	COG2177	Part of the ABC transporter FtsEX involved in
FOB75_RS13320	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOB75_RS13325	COG0705	Rhomboid family
FOB75_RS13330	COG1580	Controls the rotational direction of flagella during chemotaxis
FOB75_RS13335	COG3161	chorismate lyase activity
FOB75_RS13340	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FOB75_RS13345	COG2937	Belongs to the GPAT DAPAT family
FOB75_RS13360	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FOB75_RS13365	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
FOB75_RS13370	COG0534	Mate efflux family protein
FOB75_RS13375	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOB75_RS13390	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FOB75_RS13395	COG4206	TonB-dependent receptor
FOB75_RS13405	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FOB75_RS13470	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOB75_RS13480	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FOB75_RS13515	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FOB75_RS13525	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FOB75_RS13530	COG0250	Participates in transcription elongation, termination and antitermination
FOB75_RS13535	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FOB75_RS13540	COG0081	regulation of translation
FOB75_RS13545	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FOB75_RS13550	COG0222	ribosome binding
FOB75_RS13555	COG0085	RNA polymerase activity
FOB75_RS13560	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FOB75_RS13565	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
FOB75_RS13570	COG2816	NAD+ diphosphatase activity
FOB75_RS13585	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FOB75_RS13590	COG1573	uracil-dna glycosylase
FOB75_RS13595	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FOB75_RS13605	COG1253	flavin adenine dinucleotide binding
FOB75_RS13620	COG0151	Belongs to the GarS family
FOB75_RS13630	COG0138	bifunctional purine biosynthesis protein purh
FOB75_RS13640	COG0789	Transcriptional regulator
FOB75_RS13645	COG3710	Transcriptional regulator
FOB75_RS13655	COG0531	amino acid
FOB75_RS13660	COG1982	Orn Lys Arg decarboxylase major
FOB75_RS13715	COG3706	GGDEF domain
FOB75_RS13720	COG0488	(ABC) transporter
FOB75_RS13730	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FOB75_RS13735	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FOB75_RS13740	COG2264	protein methyltransferase activity
FOB75_RS13750	COG0439	Biotin carboxylase
FOB75_RS13755	COG0511	ligase activity, forming carbon-carbon bonds
FOB75_RS13760	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FOB75_RS13765	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FOB75_RS13780	COG2814	Major facilitator Superfamily
FOB75_RS13785	COG2205	protein histidine kinase activity
FOB75_RS13785	COG0784	Response regulator, receiver
FOB75_RS13810	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FOB75_RS13820	COG3263	regulation of cellular component size
FOB75_RS13830	COG4232	protein-disulfide reductase activity
FOB75_RS13835	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FOB75_RS13840	COG1027	Aspartate ammonia-lyase
FOB75_RS13845	COG3030	protein affecting phage T7 exclusion by the F plasmid
FOB75_RS13850	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FOB75_RS13860	COG2205	protein histidine kinase activity
FOB75_RS13865	COG0745	RESPONSE REGULATOR receiver
FOB75_RS13870	COG3678	ATP-independent chaperone mediated protein folding
FOB75_RS13880	COG0205	6-phosphofructokinase activity
FOB75_RS13885	COG0534	Mate efflux family protein
FOB75_RS13895	COG0459	protein refolding
FOB75_RS13910	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FOB75_RS13920	COG1509	lysine 2,3-aminomutase activity
FOB75_RS13925	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FOB75_RS13935	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
FOB75_RS13940	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
FOB75_RS13945	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FOB75_RS13950	COG1053	succinate dehydrogenase
FOB75_RS13960	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
FOB75_RS13980	COG4942	peptidase
FOB75_RS13985	COG1045	serine acetyltransferase
FOB75_RS13990	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FOB75_RS13995	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FOB75_RS14000	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOB75_RS14010	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FOB75_RS14025	COG0471	metal ion transport
FOB75_RS14030	COG0688	phosphatidylethanolamine metabolic process
FOB75_RS14035	COG1162	GTPase activity
FOB75_RS14040	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FOB75_RS14110	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FOB75_RS14115	COG0802	atpase or kinase
FOB75_RS14125	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FOB75_RS14130	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FOB75_RS14140	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FOB75_RS14145	COG0330	HflC and HflK could
FOB75_RS14150	COG0330	HflC and HflK could
FOB75_RS14155	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
FOB75_RS14160	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FOB75_RS14170	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
FOB75_RS14175	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FOB75_RS14175	COG1017	nitric oxide dioxygenase activity
FOB75_RS14180	COG1959	2 iron, 2 sulfur cluster binding
FOB75_RS14185	COG0557	exoribonuclease II activity
FOB75_RS14190	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FOB75_RS14195	COG0546	phosphoglycolate phosphatase activity
FOB75_RS14200	COG0180	Tryptophanyl-tRNA synthetase
FOB75_RS14230	COG0512	Glutamine amidotransferase of anthranilate synthase
FOB75_RS14235	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FOB75_RS14245	COG1012	belongs to the aldehyde dehydrogenase family
FOB75_RS14255	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FOB75_RS14260	COG3954	Phosphoribulokinase
FOB75_RS14265	COG3089	Belongs to the UPF0270 family
FOB75_RS14270	COG0429	hydrolase of the alpha beta-hydrolase fold
FOB75_RS14280	COG0488	(ABC) transporter
FOB75_RS14290	COG2249	NAD(P)H dehydrogenase (quinone) activity
FOB75_RS14305	COG1047	Peptidyl-prolyl cis-trans
FOB75_RS14315	COG1446	asparaginase
FOB75_RS14320	COG2900	Belongs to the SlyX family
FOB75_RS14330	COG0545	Peptidyl-prolyl cis-trans isomerase
FOB75_RS14335	COG2964	Protein conserved in bacteria
FOB75_RS14340	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
FOB75_RS14345	COG2923	Belongs to the DsrF TusC family
FOB75_RS14360	COG0049	tRNA binding
FOB75_RS14365	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FOB75_RS14370	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FOB75_RS14375	COG2906	2 iron, 2 sulfur cluster binding
FOB75_RS14385	COG0281	malic enzyme
FOB75_RS14395	COG0626	cystathionine gamma-synthase activity
FOB75_RS14400	COG0460	homoserine dehydrogenase
FOB75_RS14400	COG0527	aspartate kinase activity
FOB75_RS14405	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FOB75_RS14415	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FOB75_RS14420	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOB75_RS14425	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FOB75_RS14430	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FOB75_RS14435	COG0137	argininosuccinate synthase activity
FOB75_RS14440	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FOB75_RS14440	COG0165	Argininosuccinate lyase
FOB75_RS14455	COG0678	peroxiredoxin activity
FOB75_RS14455	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FOB75_RS14465	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FOB75_RS14495	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FOB75_RS14500	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FOB75_RS14510	COG0338	D12 class N6 adenine-specific DNA methyltransferase
FOB75_RS14515	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FOB75_RS14520	COG0360	Binds together with S18 to 16S ribosomal RNA
FOB75_RS14525	COG2965	DNA replication, synthesis of RNA primer
FOB75_RS14535	COG0359	binds to the 23S rRNA
FOB75_RS14550	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FOB75_RS14560	COG0432	Pfam Uncharacterised protein family UPF0047
FOB75_RS14565	COG0166	Belongs to the GPI family
FOB75_RS14575	COG0735	belongs to the Fur family
FOB75_RS14585	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FOB75_RS14610	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FOB75_RS14615	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FOB75_RS14620	COG0175	sulfate reduction
FOB75_RS14710	COG1410	methionine synthase
FOB75_RS14710	COG0646	methionine synthase
FOB75_RS14715	COG0527	aspartate kinase activity
FOB75_RS14725	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FOB75_RS14735	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FOB75_RS14750	COG0629	single-stranded DNA binding
FOB75_RS14755	COG2200	EAL domain
FOB75_RS14755	COG2199	diguanylate cyclase activity
FOB75_RS14780	COG3267	Type II secretory pathway component ExeA
FOB75_RS14780	COG3409	Peptidoglycan-binding domain 1 protein
FOB75_RS14790	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FOB75_RS14795	COG1459	type II secretion system
FOB75_RS14805	COG2165	general secretion pathway protein
FOB75_RS14840	COG1077	Cell shape determining protein MreB Mrl
FOB75_RS14845	COG1792	Involved in formation and maintenance of cell shape
FOB75_RS14850	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FOB75_RS14855	COG0424	maF-like protein
FOB75_RS14865	COG3164	Protein of unknown function
FOB75_RS14870	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FOB75_RS14875	COG0312	modulator of DNA gyrase
FOB75_RS14880	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FOB75_RS14885	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FOB75_RS14900	COG0564	pseudouridine synthase activity
FOB75_RS14905	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FOB75_RS14910	COG3028	Belongs to the UPF0307 family
FOB75_RS14915	COG0312	modulator of DNA gyrase
FOB75_RS14920	COG2239	Acts as a magnesium transporter
FOB75_RS14925	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOB75_RS14930	COG1660	Displays ATPase and GTPase activities
FOB75_RS14935	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOB75_RS14940	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FOB75_RS14950	COG1137	ATPase activity
FOB75_RS14955	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FOB75_RS14965	COG0517	IMP dehydrogenase activity
FOB75_RS14965	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FOB75_RS14975	COG1127	ABC transporter
FOB75_RS14980	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FOB75_RS14985	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FOB75_RS14990	COG2854	intermembrane phospholipid transfer
FOB75_RS15000	COG5007	Belongs to the BolA IbaG family
FOB75_RS15005	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FOB75_RS15010	COG0204	Acyl-transferase
FOB75_RS15015	COG0251	oxidation-reduction process
FOB75_RS15020	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
FOB75_RS15025	COG0540	Belongs to the ATCase OTCase family
FOB75_RS15035	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FOB75_RS15040	COG2235	arginine
FOB75_RS15070	COG0525	valine-tRNA ligase activity
FOB75_RS15075	COG2927	DNA polymerase III (CHI subunit)
FOB75_RS15080	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FOB75_RS15085	COG0795	lipopolysaccharide-transporting ATPase activity
FOB75_RS15090	COG0795	lipopolysaccharide-transporting ATPase activity
FOB75_RS15105	COG1028	Short-chain dehydrogenase reductase Sdr
FOB75_RS15190	COG0726	polysaccharide deacetylase
FOB75_RS15195	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOB75_RS15200	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOB75_RS15205	COG1447	Phosphotransferase system cellobiose-specific component IIA
FOB75_RS15210	COG1486	melibiose metabolic process
FOB75_RS15215	COG3394	polysaccharide catabolic process
FOB75_RS15225	COG3437	response regulator, receiver
FOB75_RS15275	COG1012	belongs to the aldehyde dehydrogenase family
FOB75_RS15345	COG0741	lytic transglycosylase activity
FOB75_RS15350	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
FOB75_RS15360	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FOB75_RS15370	COG2066	Belongs to the glutaminase family
FOB75_RS15375	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FOB75_RS15380	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FOB75_RS15390	COG1872	DUF167
FOB75_RS15395	COG0762	integral membrane protein
FOB75_RS15400	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FOB75_RS15405	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FOB75_RS15420	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FOB75_RS15425	COG1678	Uncharacterized ACR, COG1678
FOB75_RS15430	COG0189	ligase activity
FOB75_RS15435	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FOB75_RS15440	COG2356	endonuclease I
FOB75_RS15445	COG3091	SprT-like family
FOB75_RS15455	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FOB75_RS15465	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FOB75_RS15470	COG0583	DNA-binding transcription factor activity
FOB75_RS15475	COG4771	TonB-dependent receptor
FOB75_RS15480	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FOB75_RS15485	COG0126	phosphoglycerate kinase activity
FOB75_RS15490	COG0191	fructose-bisphosphate aldolase activity
FOB75_RS15495	COG0668	transmembrane transport
FOB75_RS15500	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FOB75_RS15510	COG0583	DNA-binding transcription factor activity
FOB75_RS15520	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FOB75_RS15525	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FOB75_RS15530	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FOB75_RS15540	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
FOB75_RS15550	COG3079	Belongs to the UPF0149 family
FOB75_RS15555	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FOB75_RS15560	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FOB75_RS15575	COG0354	folic acid binding
FOB75_RS15580	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FOB75_RS15590	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FOB75_RS15600	COG1595	DNA-templated transcription, initiation
FOB75_RS15605	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
FOB75_RS15615	COG3086	response to oxidative stress
FOB75_RS15620	COG0481	GTPase activity
FOB75_RS15630	COG0571	ribonuclease III activity
FOB75_RS15635	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FOB75_RS15640	COG1381	Involved in DNA repair and RecF pathway recombination
FOB75_RS15645	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FOB75_RS15650	COG0736	holo-[acyl-carrier-protein] synthase activity
FOB75_RS15665	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FOB75_RS15675	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FOB75_RS15680	COG3956	TIGRFAM MazG family protein
FOB75_RS15685	COG0504	CTP synthase activity
FOB75_RS15690	COG0148	phosphopyruvate hydratase activity
FOB75_RS15695	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
FOB75_RS15700	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FOB75_RS15705	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FOB75_RS15710	COG0585	pseudouridine synthase activity
FOB75_RS15715	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FOB75_RS15720	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FOB75_RS15735	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FOB75_RS15740	COG1546	Belongs to the CinA family
FOB75_RS15745	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FOB75_RS15750	COG2137	regulation of response to DNA damage stimulus
FOB75_RS15755	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FOB75_RS15760	COG0527	aspartate kinase activity
FOB75_RS15820	COG3630	sodium ion export across plasma membrane
FOB75_RS15825	COG0511	ligase activity, forming carbon-carbon bonds
FOB75_RS15825	COG5016	pyruvate
FOB75_RS15830	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
FOB75_RS15840	COG1238	metal cluster binding
FOB75_RS15845	COG0612	Peptidase, M16
FOB75_RS15850	COG2918	glutathione biosynthetic process
FOB75_RS15860	COG1854	S-ribosylhomocysteine lyase activity
FOB75_RS15865	COG4536	flavin adenine dinucleotide binding
FOB75_RS15870	COG4137	Cytochrome C assembly protein
FOB75_RS15875	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FOB75_RS15880	COG0228	four-way junction DNA binding
FOB75_RS15885	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FOB75_RS15890	COG0336	Belongs to the RNA methyltransferase TrmD family
FOB75_RS15895	COG0335	large ribosomal subunit rRNA binding
FOB75_RS15900	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FOB75_RS15905	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
FOB75_RS15910	COG0237	dephospho-CoA kinase activity
FOB75_RS15920	COG1459	type II secretion system
FOB75_RS15925	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FOB75_RS15935	COG0157	Belongs to the NadC ModD family
FOB75_RS15945	COG2186	Transcriptional regulator
FOB75_RS15950	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FOB75_RS15955	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOB75_RS15960	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOB75_RS15975	COG0288	reversible hydration of carbon dioxide
FOB75_RS15980	COG0659	secondary active sulfate transmembrane transporter activity
FOB75_RS15990	COG1131	(ABC) transporter
FOB75_RS15995	COG0842	Transport permease protein
FOB75_RS16005	COG1560	Kdo2-lipid A biosynthetic process
FOB75_RS16015	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FOB75_RS16020	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FOB75_RS16025	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FOB75_RS16040	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FOB75_RS16055	COG1489	DNA binding
FOB75_RS16060	COG1643	Atp-dependent helicase
FOB75_RS16065	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOB75_RS16070	COG1752	Esterase of the alpha-beta hydrolase superfamily
FOB75_RS16075	COG1049	propionate catabolic process, 2-methylcitrate cycle
FOB75_RS16080	COG3112	Uncharacterised protein family (UPF0231)
FOB75_RS16090	COG0004	ammonium transporteR
FOB75_RS16095	COG1840	ABC-type Fe3 transport system, periplasmic component
FOB75_RS16105	COG3842	ATPase activity
FOB75_RS16110	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FOB75_RS16125	COG2971	BadF BadG BcrA BcrD
FOB75_RS16135	COG4608	Belongs to the ABC transporter superfamily
FOB75_RS16140	COG0444	Belongs to the ABC transporter superfamily
FOB75_RS16145	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOB75_RS16155	COG0747	negative chemotaxis
FOB75_RS16160	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOB75_RS16160	COG2205	protein histidine kinase activity
FOB75_RS16160	COG2198	Histidine kinase
FOB75_RS16160	COG0784	Response regulator, receiver
FOB75_RS16170	COG2813	Specifically methylates the guanine in position
FOB75_RS16175	COG0628	permease
FOB75_RS16180	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FOB75_RS16185	COG0316	Belongs to the HesB IscA family
FOB75_RS16195	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOB75_RS16200	COG0739	heme binding
FOB75_RS16205	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FOB75_RS16215	COG2027	D-alanyl-D-alanine carboxypeptidase
FOB75_RS16220	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FOB75_RS16225	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FOB75_RS16230	COG1534	Rna-binding protein
FOB75_RS16235	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FOB75_RS16240	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FOB75_RS16245	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FOB75_RS16250	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FOB75_RS16260	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FOB75_RS16275	COG0779	Required for maturation of 30S ribosomal subunits
FOB75_RS16280	COG0195	Participates in both transcription termination and antitermination
FOB75_RS16285	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FOB75_RS16290	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FOB75_RS16295	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FOB75_RS16300	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FOB75_RS16305	COG1185	polyribonucleotide nucleotidyltransferase activity
FOB75_RS16320	COG0534	Mate efflux family protein
FOB75_RS16325	COG0826	peptidase U32
FOB75_RS16330	COG0826	peptidase U32
FOB75_RS16340	COG3154	lipid carrier protein
FOB75_RS16345	COG3153	acetyltransferase
FOB75_RS16365	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FOB75_RS16375	COG0084	hydrolase, TatD family'
FOB75_RS16380	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOB75_RS16385	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FOB75_RS16390	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FOB75_RS16395	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FOB75_RS16400	COG0813	purine-nucleoside phosphorylase activity
FOB75_RS16410	COG0560	Phosphoserine phosphatase
FOB75_RS16420	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FOB75_RS16425	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FOB75_RS16430	COG0583	DNA-binding transcription factor activity
FOB75_RS16440	COG1022	Amp-dependent synthetase and ligase
FOB75_RS16445	COG2169	Transcriptional regulator
FOB75_RS16470	COG4964	Belongs to the GSP D family
FOB75_RS16525	COG1902	pentaerythritol trinitrate reductase activity
FOB75_RS16530	COG0346	lactoylglutathione lyase activity
FOB75_RS16550	COG2239	Acts as a magnesium transporter
FOB75_RS16570	COG0242	peptide deformylase activity
FOB75_RS16615	COG2176	DNA-directed DNA polymerase activity
FOB75_RS16620	COG0583	DNA-binding transcription factor activity
FOB75_RS16625	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FOB75_RS16630	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
FOB75_RS16650	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FOB75_RS16650	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FOB75_RS16655	COG0509	glycine decarboxylation via glycine cleavage system
FOB75_RS16660	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FOB75_RS16700	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
FOB75_RS16700	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOB75_RS16700	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOB75_RS16705	COG1105	Belongs to the carbohydrate kinase PfkB family
FOB75_RS16710	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOB75_RS16710	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOB75_RS16715	COG1609	Transcriptional regulator
FOB75_RS16735	COG2203	Gaf domain
FOB75_RS16735	COG2200	EAL domain
FOB75_RS16735	COG2199	diguanylate cyclase activity
FOB75_RS16740	COG0765	amino acid transport
FOB75_RS16745	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOB75_RS16750	COG0765	amino acid transport
FOB75_RS16755	COG1126	abc transporter atp-binding protein
FOB75_RS16760	COG0469	pyruvate kinase activity
FOB75_RS16765	COG2271	Major facilitator Superfamily
FOB75_RS16790	COG1979	alcohol dehydrogenase
FOB75_RS16795	COG2207	Transcriptional regulator
FOB75_RS16810	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FOB75_RS16815	COG2759	Belongs to the formate--tetrahydrofolate ligase family
FOB75_RS16820	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOB75_RS16840	COG3437	response regulator, receiver
FOB75_RS16840	COG0784	Response regulator, receiver
FOB75_RS16850	COG0546	phosphoglycolate phosphatase activity
FOB75_RS16865	COG0840	transmembrane signaling receptor activity
FOB75_RS16875	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
FOB75_RS16880	COG0513	Belongs to the DEAD box helicase family
FOB75_RS16885	COG4943	cyclic-guanylate-specific phosphodiesterase activity
FOB75_RS16900	COG3038	cytochrome b561
FOB75_RS16905	COG2353	YceI-like domain
FOB75_RS16910	COG2116	formate transmembrane transporter activity
FOB75_RS16915	COG0583	DNA-binding transcription factor activity
FOB75_RS16925	COG3593	DNA synthesis involved in DNA repair
FOB75_RS16930	COG0737	Belongs to the 5'-nucleotidase family
FOB75_RS16935	COG0861	Integral membrane protein TerC family
FOB75_RS16950	COG2267	carboxylic ester hydrolase activity
FOB75_RS16955	COG2067	long-chain fatty acid transport protein
FOB75_RS16970	COG2050	protein possibly involved in aromatic compounds catabolism
FOB75_RS16980	COG4533	DNA binding
FOB75_RS17005	COG0484	heat shock protein binding
FOB75_RS17015	COG3300	MHYT domain
FOB75_RS17015	COG5001	Diguanylate cyclase
FOB75_RS17020	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FOB75_RS17030	COG4181	ATPase activity
FOB75_RS17035	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FOB75_RS17045	COG1984	allophanate hydrolase subunit 2
FOB75_RS17050	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FOB75_RS17055	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FOB75_RS17060	COG5001	Diguanylate cyclase
FOB75_RS17060	COG3447	MASE1 domain protein
FOB75_RS17060	COG5002	protein histidine kinase activity
FOB75_RS17065	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FOB75_RS17080	COG0583	DNA-binding transcription factor activity
FOB75_RS17085	COG0045	succinate-CoA ligase (ADP-forming) activity
FOB75_RS17085	COG1042	CoA-binding domain protein
FOB75_RS17085	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOB75_RS17095	COG1181	Belongs to the D-alanine--D-alanine ligase family
FOB75_RS17105	COG0023	Translation Initiation Factor
FOB75_RS17155	COG4128	Pfam Zonular occludens toxin
FOB75_RS17195	COG0589	response to stress
FOB75_RS17200	COG3140	Belongs to the UPF0181 family
FOB75_RS17225	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FOB75_RS17230	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FOB75_RS17255	COG5001	Diguanylate cyclase
FOB75_RS17255	COG4251	negative regulation of phosphorylation
FOB75_RS17255	COG3706	GGDEF domain
FOB75_RS17255	COG2203	Gaf domain
FOB75_RS17265	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FOB75_RS17270	COG4149	molybdate abc transporter
FOB75_RS17275	COG0725	ABC transporter, periplasmic molybdate-binding protein
FOB75_RS17280	COG1492	cobalamin metabolic process
FOB75_RS17285	COG3111	PFAM Bacterial OB fold (BOF) protein
FOB75_RS17295	COG4067	protein conserved in archaea
FOB75_RS17295	COG0189	ligase activity
FOB75_RS17315	COG0534	Mate efflux family protein
FOB75_RS17320	COG0602	queuosine metabolic process
FOB75_RS17325	COG1328	CTP reductase activity
FOB75_RS17340	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOB75_RS17370	COG0243	molybdopterin cofactor binding
FOB75_RS17380	COG0583	DNA-binding transcription factor activity
FOB75_RS17385	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FOB75_RS17395	COG2197	response regulator
FOB75_RS17400	COG3851	Histidine kinase
FOB75_RS17405	COG2271	Major facilitator Superfamily
FOB75_RS17430	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOB75_RS17435	COG3118	belongs to the thioredoxin family
FOB75_RS17445	COG2205	protein histidine kinase activity
FOB75_RS17445	COG3292	Two component regulator propeller
FOB75_RS17445	COG0745	RESPONSE REGULATOR receiver
FOB75_RS17450	COG0534	Mate efflux family protein
FOB75_RS17485	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FOB75_RS17505	COG2116	formate transmembrane transporter activity
FOB75_RS17515	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FOB75_RS17520	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FOB75_RS17560	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FOB75_RS17560	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FOB75_RS17605	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FOB75_RS17625	COG0277	FAD linked oxidase domain protein
FOB75_RS17630	COG0583	DNA-binding transcription factor activity
FOB75_RS17650	COG2425	protein containing a von Willebrand factor type A (vWA) domain
FOB75_RS17665	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
FOB75_RS17680	COG1288	antiporter activity
FOB75_RS17690	COG2814	Major facilitator Superfamily
FOB75_RS17700	COG3040	lipid binding
FOB75_RS17720	COG0419	ATPase involved in DNA repair
FOB75_RS17725	COG0420	3'-5' exonuclease activity
FOB75_RS17795	COG0631	protein serine/threonine phosphatase activity
FOB75_RS17835	COG0515	serine threonine protein kinase
FOB75_RS17835	COG2815	serine threonine protein kinase
FOB75_RS17890	COG2146	nitrite reductase [NAD(P)H] activity
FOB75_RS17890	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FOB75_RS17895	COG1116	anion transmembrane transporter activity
FOB75_RS17900	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOB75_RS17905	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FOB75_RS17915	COG3707	response regulator
FOB75_RS17935	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FOB75_RS17935	COG1648	precorrin-2 dehydrogenase activity
FOB75_RS17940	COG0243	molybdopterin cofactor binding
FOB75_RS17950	COG0814	amino acid
FOB75_RS17980	COG1785	Belongs to the alkaline phosphatase family
FOB75_RS17995	COG0745	RESPONSE REGULATOR receiver
FOB75_RS18025	COG2847	Copper chaperone PCu(A)C
FOB75_RS18030	COG0443	Heat shock 70 kDa protein
FOB75_RS18065	COG0625	glutathione transferase activity
FOB75_RS18080	COG4160	amino acid transport
FOB75_RS18085	COG4215	(ABC) transporter
FOB75_RS18090	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOB75_RS18095	COG1126	abc transporter atp-binding protein
FOB75_RS18125	COG1902	pentaerythritol trinitrate reductase activity
FOB75_RS18140	COG0109	protoheme IX farnesyltransferase activity
FOB75_RS18145	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FOB75_RS18150	COG1845	cytochrome c oxidase, subunit III
FOB75_RS18155	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FOB75_RS18160	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FOB75_RS18165	COG1028	Short-chain dehydrogenase reductase Sdr
FOB75_RS18175	COG1024	Enoyl-CoA hydratase
FOB75_RS18180	COG1024	Enoyl-CoA hydratase
FOB75_RS18195	COG0183	Belongs to the thiolase family
FOB75_RS18205	COG1960	acyl-CoA dehydrogenase activity
FOB75_RS18210	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FOB75_RS18215	COG1024	Enoyl-CoA hydratase
FOB75_RS18225	COG5413	integral membrane protein
FOB75_RS18240	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FOB75_RS18250	COG5001	Diguanylate cyclase
FOB75_RS18255	COG0513	Belongs to the DEAD box helicase family
FOB75_RS18260	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
FOB75_RS18275	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FOB75_RS18295	COG0641	radical SAM
FOB75_RS18320	COG0840	transmembrane signaling receptor activity
FOB75_RS18325	COG1119	ATPase activity
FOB75_RS18330	COG2200	EAL domain
FOB75_RS18350	COG0513	Belongs to the DEAD box helicase family
FOB75_RS18355	COG0523	cobalamin synthesis protein
FOB75_RS18365	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
FOB75_RS18375	COG0133	tryptophan synthase activity
FOB75_RS18380	COG4628	conserved protein (DUF2132)
FOB75_RS18385	COG0513	Belongs to the DEAD box helicase family
FOB75_RS18390	COG3530	Putative quorum-sensing-regulated virulence factor
FOB75_RS18415	COG2154	pterin-4-alpha-carbinolamine dehydratase
FOB75_RS18420	COG3186	Phenylalanine-4-hydroxylase
FOB75_RS18425	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FOB75_RS18430	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FOB75_RS18465	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
FOB75_RS18470	COG1454	alcohol dehydrogenase
FOB75_RS18475	COG2133	pyrroloquinoline quinone binding
FOB75_RS18485	COG0783	Belongs to the Dps family
FOB75_RS18490	COG0840	transmembrane signaling receptor activity
FOB75_RS18500	COG0577	efflux transmembrane transporter activity
FOB75_RS18500	COG1136	(ABC) transporter
FOB75_RS18520	COG2199	diguanylate cyclase activity
FOB75_RS18535	COG3036	rescue of stalled ribosome
FOB75_RS18540	COG1278	Cold shock
FOB75_RS18575	COG0545	Peptidyl-prolyl cis-trans isomerase
FOB75_RS18580	COG0109	protoheme IX farnesyltransferase activity
FOB75_RS18585	COG1612	heme a metabolic process
FOB75_RS18610	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
FOB75_RS18620	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FOB75_RS18625	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FOB75_RS18635	COG1280	lysine exporter protein (LysE YggA)
FOB75_RS18640	COG2207	Transcriptional regulator
FOB75_RS18665	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FOB75_RS18670	COG0697	spore germination
FOB75_RS18695	COG2814	Major facilitator Superfamily
FOB75_RS18700	COG0583	DNA-binding transcription factor activity
FOB75_RS18705	COG5001	Diguanylate cyclase
FOB75_RS18710	COG0739	heme binding
FOB75_RS18735	COG3314	Sporulation integral membrane protein YlbJ
FOB75_RS18750	COG0814	amino acid
FOB75_RS18770	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FOB75_RS18775	COG1072	(Pantothenic acid kinase))
FOB75_RS18785	COG1063	alcohol dehydrogenase
FOB75_RS18790	COG2213	PTS system mannitol-specific
FOB75_RS18795	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOB75_RS18815	COG0798	PFAM Bile acid sodium symporter
FOB75_RS18825	COG1881	PFAM PEBP family protein
FOB75_RS18835	COG2706	6-phosphogluconolactonase activity
FOB75_RS18855	COG1131	(ABC) transporter
FOB75_RS18860	COG0842	Transport permease protein
FOB75_RS18875	COG3383	formate dehydrogenase (NAD+) activity
FOB75_RS18900	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOB75_RS18930	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOB75_RS18940	COG2067	long-chain fatty acid transport protein
FOB75_RS18950	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOB75_RS18960	COG1505	serine-type exopeptidase activity
FOB75_RS18965	COG0488	(ABC) transporter
FOB75_RS18970	COG0589	response to stress
FOB75_RS18975	COG2249	NAD(P)H dehydrogenase (quinone) activity
FOB75_RS18995	COG0366	Alpha amylase catalytic
FOB75_RS19005	COG4934	collagen metabolic process
FOB75_RS19020	COG0583	DNA-binding transcription factor activity
FOB75_RS19030	COG0783	Belongs to the Dps family
FOB75_RS19035	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FOB75_RS19065	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FOB75_RS19075	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FOB75_RS19085	COG0784	Response regulator, receiver
FOB75_RS19085	COG0835	chemotaxis
FOB75_RS19095	COG0748	coenzyme F420 binding
FOB75_RS19100	COG3721	Heme iron utilization protein
FOB75_RS19110	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
FOB75_RS19115	COG0811	peptide transport
FOB75_RS19120	COG0848	biopolymer transport protein
FOB75_RS19130	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOB75_RS19135	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FOB75_RS19180	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FOB75_RS19185	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FOB75_RS19190	COG0633	Ferredoxin
FOB75_RS19190	COG3217	Mosc domain protein beta barrel domain protein
FOB75_RS19190	COG3217	Mosc domain protein beta barrel domain protein
FOB75_RS19190	COG0633	Ferredoxin
FOB75_RS19200	COG0401	homolog of Blt101
FOB75_RS19210	COG0418	dihydroorotase activity
FOB75_RS19215	COG2354	Protein conserved in bacteria
FOB75_RS19245	COG3833	ABC-type maltose transport systems, permease component
FOB75_RS19250	COG1175	transmembrane transport
FOB75_RS19260	COG3842	ATPase activity
FOB75_RS19290	COG0438	transferase activity, transferring glycosyl groups
FOB75_RS19320	COG3097	Belongs to the UPF0267 family
FOB75_RS19325	COG1309	transcriptional regulator
FOB75_RS19330	COG2130	NADP-dependent
FOB75_RS19340	COG0753	catalase activity
FOB75_RS19345	COG2084	Dehydrogenase
FOB75_RS19350	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOB75_RS19355	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOB75_RS19365	COG2207	Transcriptional regulator
FOB75_RS19370	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOB75_RS19370	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOB75_RS19370	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOB75_RS19385	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FOB75_RS19390	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
FOB75_RS19400	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FOB75_RS19405	COG0569	domain protein
FOB75_RS19415	COG2205	protein histidine kinase activity
FOB75_RS19420	COG1132	(ABC) transporter
FOB75_RS19425	COG4774	siderophore transport
FOB75_RS19430	COG1120	ATPase activity
FOB75_RS19435	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FOB75_RS19485	COG2197	response regulator
FOB75_RS19495	COG0840	transmembrane signaling receptor activity
FOB75_RS19505	COG0714	Associated with various cellular activities
FOB75_RS19525	COG2304	oxidoreductase activity
FOB75_RS19540	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FOB75_RS19545	COG0581	inorganic phosphate transmembrane transporter activity
FOB75_RS19550	COG0573	inorganic phosphate transmembrane transporter activity
FOB75_RS19585	COG1770	oligopeptidase
FOB75_RS19590	COG0513	Belongs to the DEAD box helicase family
FOB75_RS19600	COG1376	ErfK ybiS ycfS ynhG family protein
FOB75_RS19600	COG1388	LysM domain
FOB75_RS19605	COG0415	Belongs to the DNA photolyase family
FOB75_RS19610	COG0789	Transcriptional regulator
FOB75_RS19615	COG3272	Protein of unknown function (DUF1722)
FOB75_RS19625	COG0813	purine-nucleoside phosphorylase activity
FOB75_RS19640	COG3706	GGDEF domain
FOB75_RS19650	COG1566	PFAM secretion protein HlyD family protein
FOB75_RS19655	COG4720	Psort location CytoplasmicMembrane, score
FOB75_RS19660	COG1122	ATPase activity
FOB75_RS19675	COG0348	domain, Protein
FOB75_RS19680	COG0437	4 iron, 4 sulfur cluster binding
FOB75_RS19685	COG1247	-acetyltransferase
FOB75_RS19720	COG1067	ATP-dependent peptidase activity
FOB75_RS19730	COG4172	Belongs to the ABC transporter superfamily
FOB75_RS19735	COG1505	serine-type exopeptidase activity
FOB75_RS19740	COG0583	DNA-binding transcription factor activity
FOB75_RS19745	COG1620	l-lactate permease
FOB75_RS19750	COG1304	FMN binding
FOB75_RS19760	COG0668	transmembrane transport
FOB75_RS19780	COG1063	alcohol dehydrogenase
FOB75_RS19785	COG0156	8-amino-7-oxononanoate synthase activity
FOB75_RS19795	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOB75_RS19815	COG0745	RESPONSE REGULATOR receiver
FOB75_RS19850	COG0346	lactoylglutathione lyase activity
FOB75_RS19870	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FOB75_RS19950	COG1987	bacterial-type flagellum assembly
FOB75_RS19960	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FOB75_RS19975	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FOB75_RS19995	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FOB75_RS20000	COG1516	flagellar protein fliS
FOB75_RS20015	COG1580	Controls the rotational direction of flagella during chemotaxis
FOB75_RS20020	COG1191	sigma factor activity
FOB75_RS20025	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FOB75_RS20030	COG1360	Flagellar Motor Protein
FOB75_RS20060	COG1882	Formate acetyltransferase
FOB75_RS20065	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FOB75_RS20070	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FOB75_RS20080	COG0454	-acetyltransferase
FOB75_RS20090	COG2814	Major facilitator Superfamily
FOB75_RS20135	COG0628	permease
FOB75_RS20140	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
FOB75_RS20150	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FOB75_RS20160	COG4628	conserved protein (DUF2132)
FOB75_RS20165	COG0583	DNA-binding transcription factor activity
FOB75_RS20190	COG1686	Belongs to the peptidase S11 family
FOB75_RS20205	COG1054	Belongs to the UPF0176 family
FOB75_RS20210	COG3397	chitin binding
FOB75_RS20215	COG4667	esterase of the alpha-beta hydrolase superfamily
FOB75_RS20220	COG2095	MarC family integral membrane protein
FOB75_RS20275	COG1301	dicarboxylic acid transport
FOB75_RS20280	COG3339	Conserved Protein
FOB75_RS20285	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOB75_RS20290	COG0700	Nucleoside recognition
FOB75_RS20295	COG3366	ferrous iron transmembrane transporter activity
FOB75_RS20310	COG0366	Alpha amylase catalytic
FOB75_RS20315	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOB75_RS20320	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FOB75_RS20325	COG1640	4-alpha-glucanotransferase
FOB75_RS20330	COG0058	SHG alpha-glucan phosphorylase activity
FOB75_RS20345	COG2909	trisaccharide binding
FOB75_RS20360	COG1999	signal sequence binding
FOB75_RS20370	COG1263	PTS System
FOB75_RS20370	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOB75_RS20375	COG1162	GTPase activity
FOB75_RS20380	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
FOB75_RS20390	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
FOB75_RS20400	COG0531	amino acid
FOB75_RS20405	COG1982	Orn Lys Arg decarboxylase major
FOB75_RS20425	COG2356	endonuclease I
FOB75_RS20475	COG0739	heme binding
FOB75_RS20485	COG0612	Peptidase, M16
FOB75_RS20490	COG0840	transmembrane signaling receptor activity
FOB75_RS20495	COG1120	ATPase activity
FOB75_RS20500	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOB75_RS20505	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOB75_RS20510	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FOB75_RS20515	COG4772	TonB-dependent receptor
FOB75_RS20540	COG4264	IucA IucC family
FOB75_RS20545	COG0019	diaminopimelate decarboxylase activity
FOB75_RS20550	COG1653	transport
FOB75_RS20580	COG0826	peptidase U32
FOB75_RS20585	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOB75_RS20590	COG1129	ABC transporter
FOB75_RS20595	COG1879	ABC-type sugar transport system periplasmic component
FOB75_RS20600	COG1069	ribulokinase activity
FOB75_RS20610	COG2160	L-arabinose isomerase activity
FOB75_RS20635	COG1764	response to oxidative stress
FOB75_RS20640	COG1846	Transcriptional regulator
FOB75_RS20650	COG3634	alkyl hydroperoxide reductase activity
FOB75_RS20685	COG1595	DNA-templated transcription, initiation
FOB75_RS20705	COG0583	DNA-binding transcription factor activity
FOB75_RS20710	COG1486	melibiose metabolic process
FOB75_RS20725	COG2258	MOSC domain
FOB75_RS20730	COG0513	Belongs to the DEAD box helicase family
FOB75_RS20740	COG2186	Transcriptional regulator
FOB75_RS20750	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FOB75_RS20760	COG0246	Mannitol dehydrogenase
FOB75_RS20765	COG1904	glucuronate isomerase
FOB75_RS20770	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOB75_RS20775	COG0800	Aldolase
FOB75_RS20810	COG1132	(ABC) transporter
FOB75_RS20855	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FOB75_RS20885	COG0259	pyridoxamine-phosphate oxidase activity
FOB75_RS20930	COG4166	transmembrane transport
FOB75_RS20950	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FOB75_RS20955	COG1263	PTS System
FOB75_RS20955	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOB75_RS20960	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FOB75_RS20985	COG1444	tRNA N-acetyltransferase activity
FOB75_RS21010	COG4608	Belongs to the ABC transporter superfamily
FOB75_RS21015	COG0444	Belongs to the ABC transporter superfamily
FOB75_RS21025	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
FOB75_RS21025	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FOB75_RS21050	COG0217	transcriptional regulatory protein
FOB75_RS21055	COG0772	Belongs to the SEDS family
FOB75_RS21090	COG3275	phosphorelay sensor kinase activity
FOB75_RS21095	COG3279	Response regulator of the LytR AlgR family
FOB75_RS21105	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FOB75_RS21140	COG0786	glutamate:sodium symporter activity
FOB75_RS21150	COG1131	(ABC) transporter
FOB75_RS21155	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOB75_RS21160	COG0786	glutamate:sodium symporter activity
FOB75_RS21175	COG0363	glucosamine-6-phosphate deaminase activity
FOB75_RS21195	COG1741	Belongs to the pirin family
FOB75_RS21200	COG2259	Doxx family
FOB75_RS21215	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FOB75_RS21220	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FOB75_RS21230	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOB75_RS21270	COG3123	guanosine phosphorylase activity
FOB75_RS21280	COG5001	Diguanylate cyclase
FOB75_RS21290	COG0534	Mate efflux family protein
FOB75_RS21295	COG0564	pseudouridine synthase activity
FOB75_RS21310	COG0583	DNA-binding transcription factor activity
FOB75_RS21315	COG0561	phosphatase activity
FOB75_RS21325	COG2199	diguanylate cyclase activity
FOB75_RS21340	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FOB75_RS21345	COG2162	N-hydroxyarylamine O-acetyltransferase activity
FOB75_RS21350	COG0583	DNA-binding transcription factor activity
FOB75_RS21390	COG1357	PFAM Pentapeptide repeats (8 copies)
FOB75_RS21395	COG3047	cAMP biosynthetic process
FOB75_RS21425	COG3408	Glycogen debranching enzyme
FOB75_RS21425	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
FOB75_RS21430	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
FOB75_RS21470	COG3835	regulator
FOB75_RS21475	COG2610	gluconate transmembrane transporter activity
FOB75_RS21480	COG1929	Belongs to the glycerate kinase type-1 family
FOB75_RS21485	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOB75_RS21505	COG0456	acetyltransferase
FOB75_RS21520	COG1028	Short-chain dehydrogenase reductase Sdr
FOB75_RS21530	COG3005	denitrification pathway
FOB75_RS21535	COG0243	molybdopterin cofactor binding
FOB75_RS21545	COG0352	thiamine-phosphate diphosphorylase activity
FOB75_RS21550	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
FOB75_RS21555	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FOB75_RS21560	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FOB75_RS21565	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOB75_RS21570	COG1116	anion transmembrane transporter activity
FOB75_RS21575	COG0351	phosphomethylpyrimidine kinase
FOB75_RS21585	COG0312	modulator of DNA gyrase
FOB75_RS21590	COG0312	modulator of DNA gyrase
FOB75_RS21595	COG1901	pseudouridine methyltransferase
FOB75_RS21655	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FOB75_RS21665	COG0584	glycerophosphoryl diester phosphodiesterase
FOB75_RS21670	COG0039	L-malate dehydrogenase activity
FOB75_RS21675	COG0745	RESPONSE REGULATOR receiver
FOB75_RS21695	COG0811	peptide transport
FOB75_RS21700	COG0811	peptide transport
FOB75_RS21705	COG0848	biopolymer transport protein
FOB75_RS21745	COG0803	Belongs to the bacterial solute-binding protein 9 family
FOB75_RS21750	COG1121	(ABC) transporter
FOB75_RS21755	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FOB75_RS21770	COG1770	oligopeptidase
FOB75_RS21775	COG2814	Major facilitator Superfamily
FOB75_RS21780	COG0010	Belongs to the arginase family
FOB75_RS21785	COG1166	arginine decarboxylase activity
FOB75_RS21795	COG4067	protein conserved in archaea
FOB75_RS21795	COG0189	ligase activity
FOB75_RS21800	COG0189	ligase activity
FOB75_RS21810	COG0583	DNA-binding transcription factor activity
FOB75_RS21845	COG4191	Histidine kinase
FOB75_RS21855	COG2199	diguanylate cyclase activity
FOB75_RS21885	COG0579	oxidoreductase
FOB75_RS21895	COG3033	Beta-eliminating lyase
FOB75_RS21915	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOB75_RS21930	COG3706	GGDEF domain
FOB75_RS21935	COG0840	transmembrane signaling receptor activity
FOB75_RS21950	COG3706	GGDEF domain
FOB75_RS21955	COG0415	Belongs to the DNA photolyase family
FOB75_RS21960	COG3046	protein related to deoxyribodipyrimidine photolyase
FOB75_RS21975	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FOB75_RS21975	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FOB75_RS21980	COG1765	OsmC-like protein
FOB75_RS21985	COG0110	maltose O-acetyltransferase activity
FOB75_RS22025	COG1011	Hydrolase
FOB75_RS22040	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
FOB75_RS22050	COG2067	long-chain fatty acid transport protein
FOB75_RS22055	COG3240	lipase activity
FOB75_RS22085	COG1609	Transcriptional regulator
FOB75_RS22090	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FOB75_RS22095	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FOB75_RS22105	COG1840	ABC-type Fe3 transport system, periplasmic component
FOB75_RS22115	COG3842	ATPase activity
FOB75_RS22140	COG2990	Protein conserved in bacteria
FOB75_RS22155	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOB75_RS22160	COG2866	Carboxypeptidase
FOB75_RS22175	COG0583	DNA-binding transcription factor activity
FOB75_RS22195	COG3104	oligopeptide transport
FOB75_RS22200	COG1760	l-serine dehydratase
FOB75_RS22220	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FOB75_RS22230	COG0741	lytic transglycosylase activity
FOB75_RS22250	COG1815	bacterial-type flagellum-dependent cell motility
FOB75_RS22255	COG1558	bacterial-type flagellum-dependent cell motility
FOB75_RS22260	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FOB75_RS22265	COG1749	Flagellar hook protein flgE
FOB75_RS22270	COG4787	bacterial-type flagellum-dependent cell motility
FOB75_RS22275	COG4786	Flagellar basal body rod
FOB75_RS22280	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FOB75_RS22285	COG1706	bacterial-type flagellum-dependent cell motility
FOB75_RS22295	COG1256	bacterial-type flagellum assembly
FOB75_RS22295	COG4786	Flagellar basal body rod
FOB75_RS22300	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FOB75_RS22320	COG1304	FMN binding
FOB75_RS22335	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOB75_RS22345	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FOB75_RS22350	COG0459	protein refolding
FOB75_RS22370	COG0583	DNA-binding transcription factor activity
FOB75_RS22385	COG1309	transcriptional regulator
FOB75_RS22395	COG0737	Belongs to the 5'-nucleotidase family
FOB75_RS22400	COG2070	2-Nitropropane dioxygenase
FOB75_RS22405	COG3537	Alpha-1,2-mannosidase
FOB75_RS22410	COG3537	Alpha-1,2-mannosidase
FOB75_RS22420	COG3537	Alpha-1,2-mannosidase
FOB75_RS22425	COG3537	Alpha-1,2-mannosidase
FOB75_RS22430	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOB75_RS22450	COG0346	lactoylglutathione lyase activity
FOB75_RS22455	COG1349	DNA-binding transcription factor activity
FOB75_RS22480	COG1335	isochorismatase
FOB75_RS22490	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FOB75_RS22515	COG0583	DNA-binding transcription factor activity
FOB75_RS22535	COG3713	MltA-interacting MipA family protein
FOB75_RS22545	COG3015	lipoprotein NlpE involved in copper resistance
FOB75_RS22555	COG1342	Belongs to the UPF0251 family
FOB75_RS22590	COG4948	Mandelate Racemase Muconate Lactonizing
FOB75_RS22600	COG0583	DNA-binding transcription factor activity
FOB75_RS22650	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOB75_RS22710	COG3842	ATPase activity
FOB75_RS22740	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FOB75_RS22760	COG3706	GGDEF domain
FOB75_RS22780	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOB75_RS22800	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FOB75_RS22820	COG0574	Belongs to the PEP-utilizing enzyme family
FOB75_RS22820	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FOB75_RS22825	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FOB75_RS22830	COG0252	asparaginase activity
FOB75_RS22840	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FOB75_RS22845	COG0583	DNA-binding transcription factor activity
FOB75_RS22860	COG3122	Protein conserved in bacteria
FOB75_RS22875	COG1028	Short-chain dehydrogenase reductase Sdr
FOB75_RS22885	COG1063	alcohol dehydrogenase
FOB75_RS22890	COG1902	pentaerythritol trinitrate reductase activity
FOB75_RS22905	COG0583	DNA-binding transcription factor activity
FOB75_RS22915	COG0513	Belongs to the DEAD box helicase family
FOB75_RS22940	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOB75_RS22945	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOB75_RS22945	COG2207	Transcriptional regulator
FOB75_RS22965	COG3746	phosphate-selective porin O and P
FOB75_RS22985	COG1028	Short-chain dehydrogenase reductase Sdr
FOB75_RS23000	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FOB75_RS23010	COG0625	glutathione transferase activity
FOB75_RS23025	COG1686	Belongs to the peptidase S11 family
FOB75_RS23045	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FOB75_RS23065	COG1278	Cold shock
FOB75_RS23070	COG1741	Belongs to the pirin family
FOB75_RS23075	COG4667	esterase of the alpha-beta hydrolase superfamily
FOB75_RS23100	COG2814	Major facilitator Superfamily
FOB75_RS23110	COG0673	inositol 2-dehydrogenase activity
FOB75_RS23115	COG2194	sulfuric ester hydrolase activity
FOB75_RS23120	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FOB75_RS23130	COG2205	protein histidine kinase activity
FOB75_RS23135	COG0745	RESPONSE REGULATOR receiver
FOB75_RS23140	COG4221	oxidoreductase activity
FOB75_RS23160	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FOB75_RS23180	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FOB75_RS23190	COG2814	Major facilitator Superfamily
FOB75_RS23205	COG1418	mRNA catabolic process
FOB75_RS23215	COG0402	S-adenosylhomocysteine deaminase activity
FOB75_RS23220	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FOB75_RS23230	COG2239	Acts as a magnesium transporter
FOB75_RS23235	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FOB75_RS23250	COG0531	amino acid
FOB75_RS23260	COG1522	sequence-specific DNA binding
FOB75_RS23285	COG0784	Response regulator, receiver
FOB75_RS23285	COG5002	protein histidine kinase activity
FOB75_RS23285	COG2205	protein histidine kinase activity
FOB75_RS23290	COG0673	inositol 2-dehydrogenase activity
FOB75_RS23295	COG0534	Mate efflux family protein
FOB75_RS23300	COG2926	Belongs to the UPF0265 family
FOB75_RS23315	COG3132	Protein of unknown function, DUF480
FOB75_RS23320	COG2827	Endonuclease containing a URI domain
FOB75_RS23325	COG1879	ABC-type sugar transport system periplasmic component
FOB75_RS23330	COG0784	Response regulator, receiver
FOB75_RS23330	COG2205	protein histidine kinase activity
FOB75_RS23340	COG1566	PFAM secretion protein HlyD family protein
FOB75_RS23360	COG1522	sequence-specific DNA binding
FOB75_RS23390	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FOB75_RS23395	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FOB75_RS23405	COG1280	lysine exporter protein (LysE YggA)
FOB75_RS23415	COG0183	Belongs to the thiolase family
FOB75_RS23425	COG3243	poly(R)-hydroxyalkanoic acid synthase
FOB75_RS23435	COG3005	denitrification pathway
FOB75_RS23445	COG0243	molybdopterin cofactor binding
FOB75_RS23455	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FOB75_RS23460	COG3850	Histidine kinase
FOB75_RS23465	COG2197	response regulator
FOB75_RS23480	COG2195	Cleaves the N-terminal amino acid of tripeptides
FOB75_RS23500	COG0840	transmembrane signaling receptor activity
FOB75_RS23510	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FOB75_RS23525	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FOB75_RS23530	COG2814	Major facilitator Superfamily
FOB75_RS23540	COG0840	transmembrane signaling receptor activity
FOB75_RS23545	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FOB75_RS23550	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FOB75_RS23580	COG2897	thiosulfate sulfurtransferase activity
FOB75_RS23600	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FOB75_RS23610	COG0302	gtp cyclohydrolase
FOB75_RS23615	COG1914	H( )-stimulated, divalent metal cation uptake system
FOB75_RS23625	COG0038	chloride channel
FOB75_RS23640	COG4989	oxidoreductase activity
FOB75_RS23655	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FOB75_RS23655	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FOB75_RS23660	COG0516	GMP reductase activity
FOB75_RS23665	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FOB75_RS23730	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FOB75_RS23750	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FOB75_RS23765	COG1294	oxidase, subunit
FOB75_RS23770	COG1271	oxidase subunit
FOB75_RS23775	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOB75_RS23780	COG0110	maltose O-acetyltransferase activity
FOB75_RS23790	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FOB75_RS23790	COG3264	Mechanosensitive ion channel
FOB75_RS23805	COG3850	Histidine kinase
FOB75_RS23805	COG4999	Histidine kinase
FOB75_RS23805	COG2205	protein histidine kinase activity
FOB75_RS23805	COG3437	response regulator, receiver
FOB75_RS23820	COG1024	Enoyl-CoA hydratase
FOB75_RS23825	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FOB75_RS23830	COG1960	acyl-CoA dehydrogenase activity
FOB75_RS23840	COG0183	Belongs to the thiolase family
FOB75_RS23850	COG1960	acyl-CoA dehydrogenase activity
FOB75_RS23855	COG1024	Enoyl-CoA hydratase
FOB75_RS23880	COG3706	GGDEF domain
FOB75_RS23885	COG1309	transcriptional regulator
FOB75_RS23890	COG1012	belongs to the aldehyde dehydrogenase family
FOB75_RS23910	COG4175	Glycine betaine
FOB75_RS23910	COG0517	IMP dehydrogenase activity
FOB75_RS23925	COG0330	HflC and HflK could
FOB75_RS23940	COG5001	Diguanylate cyclase
FOB75_RS23940	COG3300	MHYT domain
FOB75_RS23960	COG2205	protein histidine kinase activity
FOB75_RS23960	COG0784	Response regulator, receiver
FOB75_RS24020	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FOB75_RS24025	COG5001	Diguanylate cyclase
FOB75_RS24030	COG1869	D-ribose catabolic process
FOB75_RS24035	COG1129	ABC transporter
FOB75_RS24040	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOB75_RS24045	COG1879	ABC-type sugar transport system periplasmic component
FOB75_RS24050	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOB75_RS24055	COG1609	Transcriptional regulator
FOB75_RS24070	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
FOB75_RS24080	COG4607	ABC-type enterochelin transport system periplasmic component
FOB75_RS24085	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOB75_RS24090	COG4605	iron ion homeostasis
FOB75_RS24095	COG4604	ABC transporter, ATP-binding protein
FOB75_RS24100	COG0789	Transcriptional regulator
FOB75_RS24110	COG2207	Transcriptional regulator
FOB75_RS24115	COG4206	TonB-dependent receptor
FOB75_RS24150	COG1289	transmembrane transporter activity
FOB75_RS24155	COG0210	DNA helicase
FOB75_RS24160	COG1803	Methylglyoxal synthase
FOB75_RS24165	COG1879	ABC-type sugar transport system periplasmic component
FOB75_RS24170	COG0784	Response regulator, receiver
FOB75_RS24170	COG2198	Histidine kinase
FOB75_RS24170	COG2205	protein histidine kinase activity
FOB75_RS24185	COG0745	RESPONSE REGULATOR receiver
FOB75_RS24190	COG3119	arylsulfatase activity
FOB75_RS24195	COG3119	arylsulfatase activity
FOB75_RS24210	COG3119	arylsulfatase activity
FOB75_RS24215	COG0641	radical SAM
FOB75_RS24220	COG0714	Associated with various cellular activities
FOB75_RS24250	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FOB75_RS24255	COG0583	DNA-binding transcription factor activity
FOB75_RS24260	COG1597	lipid kinase activity
FOB75_RS24265	COG3111	PFAM Bacterial OB fold (BOF) protein
FOB75_RS24285	COG0641	radical SAM
FOB75_RS24315	COG0501	Belongs to the peptidase M48B family
FOB75_RS24320	COG1704	LemA family
FOB75_RS24325	COG3069	C4-dicarboxylate transmembrane transporter activity
FOB75_RS24335	COG0456	acetyltransferase
FOB75_RS24335	COG1214	PFAM Peptidase M22, glycoprotease
FOB75_RS24355	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FOB75_RS24390	COG1278	Cold shock
FOB75_RS24435	COG0596	Alpha beta hydrolase
FOB75_RS24445	COG0583	DNA-binding transcription factor activity
FOB75_RS24480	COG2207	Transcriptional regulator
FOB75_RS24505	COG4964	Belongs to the GSP D family
FOB75_RS24580	COG3300	MHYT domain
FOB75_RS24580	COG5001	Diguanylate cyclase
FOB75_RS24585	COG2197	response regulator
FOB75_RS24590	COG3706	GGDEF domain
FOB75_RS24600	COG2197	response regulator
FOB75_RS24625	COG0784	Response regulator, receiver
FOB75_RS24625	COG0835	chemotaxis
FOB75_RS24645	COG2962	Rard protein
FOB75_RS24660	COG0671	phosphoesterase, PA-phosphatase related
FOB75_RS24675	COG2076	Multidrug Resistance protein
FOB75_RS24705	COG0471	metal ion transport
FOB75_RS24710	COG3290	protein histidine kinase activity
FOB75_RS24715	COG4565	transcriptional regulatory protein
FOB75_RS24735	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FOB75_RS24740	COG5642	Protein of unknown function (DUF2384)