locus-tag	class	description
FORC6_RS00010	COG0592	DNA-directed DNA polymerase activity
FORC6_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FORC6_RS00020	COG0187	DNA topoisomerase II activity
FORC6_RS00030	COG0071	Belongs to the small heat shock protein (HSP20) family
FORC6_RS00035	COG3977	Valine--pyruvate aminotransferase
FORC6_RS00040	COG0366	Alpha amylase catalytic
FORC6_RS00045	COG0751	glycine-tRNA ligase activity
FORC6_RS00050	COG0752	glycyl-tRNA synthetase alpha subunit
FORC6_RS00055	COG2119	membrane
FORC6_RS00065	COG0425	Belongs to the sulfur carrier protein TusA family
FORC6_RS00080	COG0604	alcohol dehydrogenase
FORC6_RS00085	COG0183	Belongs to the thiolase family
FORC6_RS00090	COG1250	3-hydroxyacyl-CoA dehydrogenase
FORC6_RS00090	COG1024	Enoyl-CoA hydratase
FORC6_RS00095	COG1739	Uncharacterized protein family UPF0029
FORC6_RS00100	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FORC6_RS00155	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FORC6_RS00160	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FORC6_RS00165	COG0352	thiamine-phosphate diphosphorylase activity
FORC6_RS00170	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FORC6_RS00175	COG2104	thiamine diphosphate biosynthetic process
FORC6_RS00180	COG2022	thiamine diphosphate biosynthetic process
FORC6_RS00190	COG0006	proline dipeptidase activity
FORC6_RS00190	COG0006	proline dipeptidase activity
FORC6_RS00220	COG3220	belongs to the UPF0276 family
FORC6_RS00230	COG0210	DNA helicase
FORC6_RS00235	COG0405	Gamma-glutamyltransferase
FORC6_RS00240	COG1280	lysine exporter protein (LysE YggA)
FORC6_RS00250	COG2962	Rard protein
FORC6_RS00255	COG0514	ATP-dependent DNA helicase (RecQ)
FORC6_RS00265	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FORC6_RS00270	COG0248	Ppx GppA phosphatase
FORC6_RS00275	COG0513	Belongs to the DEAD box helicase family
FORC6_RS00280	COG3118	belongs to the thioredoxin family
FORC6_RS00295	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FORC6_RS00300	COG0633	Ferredoxin
FORC6_RS00345	COG3071	HemY protein
FORC6_RS00350	COG2959	enzyme of heme biosynthesis
FORC6_RS00355	COG1587	Uroporphyrinogen-III synthase
FORC6_RS00360	COG0181	hydroxymethylbilane synthase activity
FORC6_RS00365	COG3072	Adenylate cyclase
FORC6_RS00370	COG1965	Belongs to the frataxin family
FORC6_RS00380	COG0019	diaminopimelate decarboxylase activity
FORC6_RS00385	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FORC6_RS00395	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FORC6_RS00400	COG1011	Hydrolase
FORC6_RS00405	COG2200	EAL domain
FORC6_RS00405	COG2199	diguanylate cyclase activity
FORC6_RS00405	COG3287	FIST C domain
FORC6_RS00410	COG3148	PFAM DTW domain containing protein
FORC6_RS00425	COG0561	phosphatase activity
FORC6_RS00430	COG2267	carboxylic ester hydrolase activity
FORC6_RS00435	COG1280	lysine exporter protein (LysE YggA)
FORC6_RS00440	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FORC6_RS00445	COG0640	Transcriptional regulator
FORC6_RS00450	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FORC6_RS00500	COG2095	MarC family integral membrane protein
FORC6_RS00510	COG0742	ribosomal rna small subunit methyltransferase
FORC6_RS00515	COG0552	protein localization to endoplasmic reticulum
FORC6_RS00520	COG2884	Cell division ATP-binding protein ftsE
FORC6_RS00525	COG2177	Part of the ABC transporter FtsEX involved in
FORC6_RS00535	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FORC6_RS00540	COG0705	Rhomboid family
FORC6_RS00545	COG1580	Controls the rotational direction of flagella during chemotaxis
FORC6_RS00550	COG3161	chorismate lyase activity
FORC6_RS00555	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FORC6_RS00560	COG2937	Belongs to the GPAT DAPAT family
FORC6_RS00565	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FORC6_RS00570	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
FORC6_RS00575	COG0534	Mate efflux family protein
FORC6_RS00580	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FORC6_RS00595	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FORC6_RS00600	COG4206	TonB-dependent receptor
FORC6_RS00610	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FORC6_RS00675	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FORC6_RS00685	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FORC6_RS00720	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FORC6_RS00725	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FORC6_RS00730	COG0250	Participates in transcription elongation, termination and antitermination
FORC6_RS00735	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FORC6_RS00740	COG0081	regulation of translation
FORC6_RS00745	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FORC6_RS00750	COG0222	ribosome binding
FORC6_RS00755	COG0085	RNA polymerase activity
FORC6_RS00760	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FORC6_RS00765	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
FORC6_RS00770	COG2816	NAD+ diphosphatase activity
FORC6_RS00785	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FORC6_RS00790	COG1573	uracil-dna glycosylase
FORC6_RS00795	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FORC6_RS00805	COG1253	flavin adenine dinucleotide binding
FORC6_RS00820	COG0151	Belongs to the GarS family
FORC6_RS00825	COG0138	bifunctional purine biosynthesis protein purh
FORC6_RS00830	COG0789	Transcriptional regulator
FORC6_RS00835	COG3710	Transcriptional regulator
FORC6_RS00840	COG0531	amino acid
FORC6_RS00845	COG1982	Orn Lys Arg decarboxylase major
FORC6_RS00910	COG3706	GGDEF domain
FORC6_RS00915	COG0488	(ABC) transporter
FORC6_RS00920	COG2814	Major facilitator Superfamily
FORC6_RS00925	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FORC6_RS00930	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FORC6_RS00935	COG2264	protein methyltransferase activity
FORC6_RS00940	COG0439	Biotin carboxylase
FORC6_RS00945	COG0511	ligase activity, forming carbon-carbon bonds
FORC6_RS00950	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FORC6_RS00955	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FORC6_RS00970	COG2814	Major facilitator Superfamily
FORC6_RS00975	COG0784	Response regulator, receiver
FORC6_RS00975	COG2198	Histidine kinase
FORC6_RS00975	COG2205	protein histidine kinase activity
FORC6_RS00995	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FORC6_RS01005	COG3263	regulation of cellular component size
FORC6_RS01015	COG4232	protein-disulfide reductase activity
FORC6_RS01020	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FORC6_RS01025	COG1027	Aspartate ammonia-lyase
FORC6_RS01035	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FORC6_RS01045	COG2205	protein histidine kinase activity
FORC6_RS01050	COG0745	RESPONSE REGULATOR receiver
FORC6_RS01055	COG3678	ATP-independent chaperone mediated protein folding
FORC6_RS01065	COG0205	6-phosphofructokinase activity
FORC6_RS01070	COG0534	Mate efflux family protein
FORC6_RS01080	COG0459	protein refolding
FORC6_RS01100	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FORC6_RS01105	COG1509	lysine 2,3-aminomutase activity
FORC6_RS01110	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FORC6_RS01120	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
FORC6_RS01125	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
FORC6_RS01130	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FORC6_RS01135	COG1053	succinate dehydrogenase
FORC6_RS01140	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
FORC6_RS01160	COG4942	peptidase
FORC6_RS01165	COG1045	serine acetyltransferase
FORC6_RS01170	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FORC6_RS01175	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FORC6_RS01180	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FORC6_RS01185	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FORC6_RS01200	COG0471	metal ion transport
FORC6_RS01205	COG0688	phosphatidylethanolamine metabolic process
FORC6_RS01210	COG1162	GTPase activity
FORC6_RS01215	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FORC6_RS01285	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FORC6_RS01290	COG0802	atpase or kinase
FORC6_RS01300	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FORC6_RS01305	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FORC6_RS01315	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FORC6_RS01320	COG0330	HflC and HflK could
FORC6_RS01325	COG0330	HflC and HflK could
FORC6_RS01330	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
FORC6_RS01335	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FORC6_RS01340	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
FORC6_RS01345	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FORC6_RS01345	COG1017	nitric oxide dioxygenase activity
FORC6_RS01350	COG1959	2 iron, 2 sulfur cluster binding
FORC6_RS01355	COG0557	exoribonuclease II activity
FORC6_RS01360	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FORC6_RS01365	COG0546	phosphoglycolate phosphatase activity
FORC6_RS01370	COG0180	Tryptophanyl-tRNA synthetase
FORC6_RS01385	COG0512	Glutamine amidotransferase of anthranilate synthase
FORC6_RS01390	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FORC6_RS01400	COG1012	belongs to the aldehyde dehydrogenase family
FORC6_RS01410	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FORC6_RS01415	COG3954	Phosphoribulokinase
FORC6_RS01420	COG3089	Belongs to the UPF0270 family
FORC6_RS01425	COG0429	hydrolase of the alpha beta-hydrolase fold
FORC6_RS01435	COG0488	(ABC) transporter
FORC6_RS01440	COG2249	NAD(P)H dehydrogenase (quinone) activity
FORC6_RS01455	COG1047	Peptidyl-prolyl cis-trans
FORC6_RS01460	COG1446	asparaginase
FORC6_RS01465	COG2900	Belongs to the SlyX family
FORC6_RS01475	COG0545	Peptidyl-prolyl cis-trans isomerase
FORC6_RS01480	COG2964	Protein conserved in bacteria
FORC6_RS01485	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
FORC6_RS01490	COG2923	Belongs to the DsrF TusC family
FORC6_RS01495	COG2168	tRNA wobble position uridine thiolation
FORC6_RS01505	COG0049	tRNA binding
FORC6_RS01510	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FORC6_RS01515	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FORC6_RS01520	COG2906	2 iron, 2 sulfur cluster binding
FORC6_RS01530	COG0281	malic enzyme
FORC6_RS01540	COG0626	cystathionine gamma-synthase activity
FORC6_RS01545	COG0527	aspartate kinase activity
FORC6_RS01545	COG0460	homoserine dehydrogenase
FORC6_RS01550	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FORC6_RS01560	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FORC6_RS01565	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FORC6_RS01570	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FORC6_RS01575	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FORC6_RS01580	COG0137	argininosuccinate synthase activity
FORC6_RS01585	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FORC6_RS01585	COG0165	Argininosuccinate lyase
FORC6_RS01595	COG0678	peroxiredoxin activity
FORC6_RS01595	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FORC6_RS01605	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FORC6_RS01635	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FORC6_RS01640	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FORC6_RS01650	COG0338	D12 class N6 adenine-specific DNA methyltransferase
FORC6_RS01655	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FORC6_RS01660	COG0360	Binds together with S18 to 16S ribosomal RNA
FORC6_RS01665	COG2965	DNA replication, synthesis of RNA primer
FORC6_RS01675	COG0359	binds to the 23S rRNA
FORC6_RS01690	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FORC6_RS01700	COG0432	Pfam Uncharacterised protein family UPF0047
FORC6_RS01705	COG0166	Belongs to the GPI family
FORC6_RS01715	COG0735	belongs to the Fur family
FORC6_RS01720	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FORC6_RS01740	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FORC6_RS01745	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FORC6_RS01750	COG0175	sulfate reduction
FORC6_RS01820	COG1410	methionine synthase
FORC6_RS01820	COG0646	methionine synthase
FORC6_RS01825	COG0527	aspartate kinase activity
FORC6_RS01835	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FORC6_RS01845	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FORC6_RS01860	COG0629	single-stranded DNA binding
FORC6_RS01865	COG2200	EAL domain
FORC6_RS01865	COG2199	diguanylate cyclase activity
FORC6_RS01890	COG3267	Type II secretory pathway component ExeA
FORC6_RS01890	COG3409	Peptidoglycan-binding domain 1 protein
FORC6_RS01900	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FORC6_RS01905	COG1459	type II secretion system
FORC6_RS01950	COG1077	Cell shape determining protein MreB Mrl
FORC6_RS01955	COG1792	Involved in formation and maintenance of cell shape
FORC6_RS01960	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FORC6_RS01965	COG0424	maF-like protein
FORC6_RS01975	COG3164	Protein of unknown function
FORC6_RS01980	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FORC6_RS01985	COG0312	modulator of DNA gyrase
FORC6_RS01990	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FORC6_RS01995	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FORC6_RS02005	COG0564	pseudouridine synthase activity
FORC6_RS02010	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FORC6_RS02015	COG3028	Belongs to the UPF0307 family
FORC6_RS02020	COG0312	modulator of DNA gyrase
FORC6_RS02025	COG2239	Acts as a magnesium transporter
FORC6_RS02030	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC6_RS02035	COG1660	Displays ATPase and GTPase activities
FORC6_RS02040	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC6_RS02045	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FORC6_RS02055	COG1137	ATPase activity
FORC6_RS02060	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FORC6_RS02070	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FORC6_RS02070	COG0517	IMP dehydrogenase activity
FORC6_RS02080	COG1127	ABC transporter
FORC6_RS02085	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FORC6_RS02090	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FORC6_RS02095	COG2854	intermembrane phospholipid transfer
FORC6_RS02105	COG5007	Belongs to the BolA IbaG family
FORC6_RS02110	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FORC6_RS02115	COG0204	Acyl-transferase
FORC6_RS02120	COG0251	oxidation-reduction process
FORC6_RS02125	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
FORC6_RS02130	COG0540	Belongs to the ATCase OTCase family
FORC6_RS02135	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FORC6_RS02140	COG2235	arginine
FORC6_RS02165	COG0525	valine-tRNA ligase activity
FORC6_RS02170	COG2927	DNA polymerase III (CHI subunit)
FORC6_RS02175	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FORC6_RS02180	COG0795	lipopolysaccharide-transporting ATPase activity
FORC6_RS02185	COG0795	lipopolysaccharide-transporting ATPase activity
FORC6_RS02200	COG1028	Short-chain dehydrogenase reductase Sdr
FORC6_RS02235	COG0726	polysaccharide deacetylase
FORC6_RS02240	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FORC6_RS02245	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FORC6_RS02250	COG1447	Phosphotransferase system cellobiose-specific component IIA
FORC6_RS02255	COG1486	melibiose metabolic process
FORC6_RS02260	COG3394	polysaccharide catabolic process
FORC6_RS02270	COG3437	response regulator, receiver
FORC6_RS02310	COG1012	belongs to the aldehyde dehydrogenase family
FORC6_RS02340	COG0840	transmembrane signaling receptor activity
FORC6_RS02380	COG0741	lytic transglycosylase activity
FORC6_RS02385	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
FORC6_RS02395	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FORC6_RS02405	COG2066	Belongs to the glutaminase family
FORC6_RS02410	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FORC6_RS02415	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FORC6_RS02425	COG1872	DUF167
FORC6_RS02430	COG0762	integral membrane protein
FORC6_RS02435	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FORC6_RS02440	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FORC6_RS02455	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FORC6_RS02460	COG1678	Uncharacterized ACR, COG1678
FORC6_RS02465	COG0189	ligase activity
FORC6_RS02470	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FORC6_RS02475	COG2356	endonuclease I
FORC6_RS02480	COG3091	SprT-like family
FORC6_RS02490	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FORC6_RS02500	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FORC6_RS02505	COG0583	DNA-binding transcription factor activity
FORC6_RS02510	COG4771	TonB-dependent receptor
FORC6_RS02515	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FORC6_RS02520	COG0126	phosphoglycerate kinase activity
FORC6_RS02525	COG0191	fructose-bisphosphate aldolase activity
FORC6_RS02530	COG0668	transmembrane transport
FORC6_RS02535	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FORC6_RS02545	COG0583	DNA-binding transcription factor activity
FORC6_RS02555	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FORC6_RS02560	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FORC6_RS02565	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FORC6_RS02575	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
FORC6_RS02580	COG3079	Belongs to the UPF0149 family
FORC6_RS02585	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FORC6_RS02590	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FORC6_RS02605	COG0354	folic acid binding
FORC6_RS02610	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FORC6_RS02615	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FORC6_RS02620	COG1595	DNA-templated transcription, initiation
FORC6_RS02625	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
FORC6_RS02635	COG3086	response to oxidative stress
FORC6_RS02640	COG0481	GTPase activity
FORC6_RS02650	COG0571	ribonuclease III activity
FORC6_RS02655	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FORC6_RS02660	COG1381	Involved in DNA repair and RecF pathway recombination
FORC6_RS02665	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FORC6_RS02670	COG0736	holo-[acyl-carrier-protein] synthase activity
FORC6_RS02680	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FORC6_RS02685	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FORC6_RS02690	COG3956	TIGRFAM MazG family protein
FORC6_RS02695	COG0504	CTP synthase activity
FORC6_RS02700	COG0148	phosphopyruvate hydratase activity
FORC6_RS02705	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
FORC6_RS02710	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FORC6_RS02715	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FORC6_RS02720	COG0585	pseudouridine synthase activity
FORC6_RS02725	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FORC6_RS02730	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FORC6_RS02745	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FORC6_RS02750	COG1546	Belongs to the CinA family
FORC6_RS02755	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FORC6_RS02760	COG2137	regulation of response to DNA damage stimulus
FORC6_RS02765	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FORC6_RS02770	COG0527	aspartate kinase activity
FORC6_RS02830	COG3630	sodium ion export across plasma membrane
FORC6_RS02835	COG0511	ligase activity, forming carbon-carbon bonds
FORC6_RS02835	COG5016	pyruvate
FORC6_RS02840	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
FORC6_RS02850	COG1238	metal cluster binding
FORC6_RS02855	COG0612	Peptidase, M16
FORC6_RS02860	COG2918	glutathione biosynthetic process
FORC6_RS02870	COG1854	S-ribosylhomocysteine lyase activity
FORC6_RS02875	COG4536	flavin adenine dinucleotide binding
FORC6_RS02880	COG4137	Cytochrome C assembly protein
FORC6_RS02885	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FORC6_RS02890	COG0228	four-way junction DNA binding
FORC6_RS02895	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FORC6_RS02900	COG0336	Belongs to the RNA methyltransferase TrmD family
FORC6_RS02905	COG0335	large ribosomal subunit rRNA binding
FORC6_RS02910	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FORC6_RS02915	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
FORC6_RS02920	COG0237	dephospho-CoA kinase activity
FORC6_RS02930	COG1459	type II secretion system
FORC6_RS02935	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FORC6_RS02945	COG0157	Belongs to the NadC ModD family
FORC6_RS02955	COG2186	Transcriptional regulator
FORC6_RS02960	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FORC6_RS02965	COG0508	dehydrogenase complex catalyzes the overall conversion of
FORC6_RS02970	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FORC6_RS02985	COG0288	reversible hydration of carbon dioxide
FORC6_RS02990	COG0659	secondary active sulfate transmembrane transporter activity
FORC6_RS02995	COG1131	(ABC) transporter
FORC6_RS03000	COG0842	Transport permease protein
FORC6_RS03005	COG1560	Kdo2-lipid A biosynthetic process
FORC6_RS03010	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FORC6_RS03015	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FORC6_RS03020	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FORC6_RS03030	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FORC6_RS03040	COG1489	DNA binding
FORC6_RS03045	COG1643	Atp-dependent helicase
FORC6_RS03050	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FORC6_RS03055	COG1752	Esterase of the alpha-beta hydrolase superfamily
FORC6_RS03060	COG1049	propionate catabolic process, 2-methylcitrate cycle
FORC6_RS03065	COG3112	Uncharacterised protein family (UPF0231)
FORC6_RS03075	COG0004	ammonium transporteR
FORC6_RS03080	COG1840	ABC-type Fe3 transport system, periplasmic component
FORC6_RS03090	COG3842	ATPase activity
FORC6_RS03095	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FORC6_RS03110	COG2971	BadF BadG BcrA BcrD
FORC6_RS03120	COG4608	Belongs to the ABC transporter superfamily
FORC6_RS03125	COG0444	Belongs to the ABC transporter superfamily
FORC6_RS03130	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FORC6_RS03140	COG0747	negative chemotaxis
FORC6_RS03145	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC6_RS03145	COG2198	Histidine kinase
FORC6_RS03145	COG2205	protein histidine kinase activity
FORC6_RS03145	COG0784	Response regulator, receiver
FORC6_RS03150	COG2813	Specifically methylates the guanine in position
FORC6_RS03155	COG0628	permease
FORC6_RS03160	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FORC6_RS03165	COG0316	Belongs to the HesB IscA family
FORC6_RS03175	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FORC6_RS03180	COG0739	heme binding
FORC6_RS03185	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FORC6_RS03190	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FORC6_RS03195	COG0047	phosphoribosylformylglycinamidine synthase activity
FORC6_RS03195	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FORC6_RS03220	COG2195	Cleaves the N-terminal amino acid of tripeptides
FORC6_RS03225	COG2252	PERMEase
FORC6_RS03230	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
FORC6_RS03235	COG1073	alpha beta
FORC6_RS03245	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FORC6_RS03250	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FORC6_RS03255	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FORC6_RS03260	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FORC6_RS03260	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FORC6_RS03280	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FORC6_RS03285	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FORC6_RS03290	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FORC6_RS03295	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FORC6_RS03300	COG0142	geranyltranstransferase activity
FORC6_RS03305	COG1722	exodeoxyribonuclease VII activity
FORC6_RS03310	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FORC6_RS03315	COG2885	chlorophyll binding
FORC6_RS03320	COG0301	tRNA thio-modification
FORC6_RS03320	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FORC6_RS03325	COG0583	DNA-binding transcription factor activity
FORC6_RS03335	COG2363	Small membrane protein
FORC6_RS03340	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
FORC6_RS03350	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FORC6_RS03355	COG1611	Belongs to the LOG family
FORC6_RS03370	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FORC6_RS03370	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FORC6_RS03380	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
FORC6_RS03385	COG1464	Belongs to the NlpA lipoprotein family
FORC6_RS03390	COG2011	ABC-type metal ion transport system permease component
FORC6_RS03395	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FORC6_RS03400	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FORC6_RS03410	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC6_RS03410	COG1263	PTS System
FORC6_RS03415	COG0366	Alpha amylase catalytic
FORC6_RS03430	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FORC6_RS03435	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FORC6_RS03440	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FORC6_RS03445	COG0321	lipoyl(octanoyl) transferase activity
FORC6_RS03450	COG2921	Belongs to the UPF0250 family
FORC6_RS03455	COG1686	Belongs to the peptidase S11 family
FORC6_RS03460	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FORC6_RS03465	COG0772	Belongs to the SEDS family
FORC6_RS03470	COG0768	penicillin binding
FORC6_RS03475	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FORC6_RS03480	COG0799	negative regulation of ribosome biogenesis
FORC6_RS03485	COG1466	dna polymerase III delta subunit
FORC6_RS03490	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
FORC6_RS03495	COG0495	leucyl-tRNA aminoacylation
FORC6_RS03500	COG2888	peptidyl-tyrosine sulfation
FORC6_RS03505	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FORC6_RS03510	COG4535	Mg2 and Co2 transporter CorC
FORC6_RS03515	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FORC6_RS03520	COG1702	phosphate starvation-inducible protein PhoH
FORC6_RS03525	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FORC6_RS03530	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FORC6_RS03645	COG0012	GTP binding
FORC6_RS03650	COG0193	aminoacyl-tRNA hydrolase activity
FORC6_RS03655	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FORC6_RS03660	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FORC6_RS03665	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
FORC6_RS03670	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FORC6_RS03675	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FORC6_RS03680	COG2890	protein-(glutamine-N5) methyltransferase activity
FORC6_RS03685	COG3094	Invasion gene expression up-regulator, SirB
FORC6_RS03690	COG2912	Transglutaminase-like superfamily
FORC6_RS03695	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FORC6_RS03700	COG0737	Belongs to the 5'-nucleotidase family
FORC6_RS03705	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FORC6_RS03710	COG1187	pseudouridine synthase activity
FORC6_RS03715	COG2840	Smr protein MutS2
FORC6_RS03745	COG2608	mercury ion transmembrane transporter activity
FORC6_RS03745	COG2217	Heavy metal translocating P-type atpase
FORC6_RS03755	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
FORC6_RS03760	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FORC6_RS03810	COG0835	chemotaxis
FORC6_RS03810	COG0784	Response regulator, receiver
FORC6_RS03815	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FORC6_RS03820	COG1815	bacterial-type flagellum-dependent cell motility
FORC6_RS03825	COG1558	bacterial-type flagellum-dependent cell motility
FORC6_RS03840	COG4787	bacterial-type flagellum-dependent cell motility
FORC6_RS03850	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FORC6_RS03855	COG1706	bacterial-type flagellum-dependent cell motility
FORC6_RS03860	COG1705	Flagellar rod assembly protein muramidase FlgJ
FORC6_RS03860	COG3951	Flagellar rod assembly protein muramidase FlgJ
FORC6_RS03870	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FORC6_RS03875	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FORC6_RS03880	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FORC6_RS03885	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FORC6_RS03890	COG2190	(PTS) system
FORC6_RS03895	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FORC6_RS03900	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC6_RS03905	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FORC6_RS03910	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
FORC6_RS03915	COG3115	cell septum assembly
FORC6_RS03920	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FORC6_RS03940	COG0330	HflC and HflK could
FORC6_RS03945	COG2194	sulfuric ester hydrolase activity
FORC6_RS03965	COG1215	transferase activity, transferring glycosyl groups
FORC6_RS03970	COG1215	transferase activity, transferring glycosyl groups
FORC6_RS03975	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
FORC6_RS03980	COG0457	Tetratricopeptide repeat
FORC6_RS03980	COG3118	belongs to the thioredoxin family
FORC6_RS03985	COG3118	belongs to the thioredoxin family
FORC6_RS03990	COG0300	oxidoreductase activity
FORC6_RS03995	COG1090	epimerase
FORC6_RS04020	COG0622	Phosphoesterase
FORC6_RS04040	COG3710	Transcriptional regulator
FORC6_RS04045	COG0326	Molecular chaperone. Has ATPase activity
FORC6_RS04050	COG0563	adenylate kinase activity
FORC6_RS04055	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FORC6_RS04060	COG3104	oligopeptide transport
FORC6_RS04065	COG0250	Participates in transcription elongation, termination and antitermination
FORC6_RS04070	COG0367	asparagine synthase
FORC6_RS04075	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FORC6_RS04075	COG4651	solute:proton antiporter activity
FORC6_RS04080	COG1846	Transcriptional regulator
FORC6_RS04080	COG1940	carbohydrate kinase activity
FORC6_RS04085	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FORC6_RS04090	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC6_RS04090	COG1263	PTS System
FORC6_RS04095	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FORC6_RS04100	COG0735	belongs to the Fur family
FORC6_RS04120	COG0596	Alpha beta hydrolase
FORC6_RS04125	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
FORC6_RS04130	COG0033	Phosphoglucomutase
FORC6_RS04140	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FORC6_RS04155	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FORC6_RS04160	COG1053	succinate dehydrogenase
FORC6_RS04165	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FORC6_RS04170	COG0567	Dehydrogenase, E1 component
FORC6_RS04175	COG0508	dehydrogenase complex catalyzes the overall conversion of
FORC6_RS04180	COG0045	succinate-CoA ligase (ADP-forming) activity
FORC6_RS04190	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FORC6_RS04195	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FORC6_RS04200	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FORC6_RS04205	COG2233	PERMEase
FORC6_RS04225	COG1393	Belongs to the ArsC family
FORC6_RS04230	COG4783	chaperone-mediated protein folding
FORC6_RS04245	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FORC6_RS04250	COG2716	regulation of RNA biosynthetic process
FORC6_RS04255	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FORC6_RS04260	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
FORC6_RS04275	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FORC6_RS04280	COG1393	Belongs to the ArsC family
FORC6_RS04305	COG2837	iron assimilation
FORC6_RS04310	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FORC6_RS04315	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FORC6_RS04320	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FORC6_RS04325	COG1334	flagellar protein FlaG
FORC6_RS04330	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FORC6_RS04340	COG1516	flagellar protein fliS
FORC6_RS04360	COG1677	Flagellar hook-basal body complex protein FliE
FORC6_RS04370	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FORC6_RS04420	COG1987	bacterial-type flagellum assembly
FORC6_RS04425	COG1684	flagellar biosynthetic protein fliR
FORC6_RS04460	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
FORC6_RS04465	COG0784	Response regulator, receiver
FORC6_RS04465	COG2198	Histidine kinase
FORC6_RS04465	COG0643	Histidine kinase
FORC6_RS04470	COG2201	protein-glutamate methylesterase activity
FORC6_RS04475	COG1192	Involved in chromosome partitioning
FORC6_RS04485	COG0835	chemotaxis
FORC6_RS04495	COG4133	protoheme IX ABC transporter activity
FORC6_RS04500	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FORC6_RS04505	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FORC6_RS04510	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FORC6_RS04515	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
FORC6_RS04520	COG1138	Cytochrome C-type biogenesis protein
FORC6_RS04525	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FORC6_RS04540	COG2853	Lipoprotein
FORC6_RS04550	COG2067	long-chain fatty acid transport protein
FORC6_RS04565	COG0183	Belongs to the thiolase family
FORC6_RS04570	COG1250	3-hydroxyacyl-CoA dehydrogenase
FORC6_RS04570	COG1024	Enoyl-CoA hydratase
FORC6_RS04585	COG2062	phosphohistidine phosphatase, SixA
FORC6_RS04590	COG2840	Smr protein MutS2
FORC6_RS04595	COG2890	protein-(glutamine-N5) methyltransferase activity
FORC6_RS04600	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FORC6_RS04605	COG2860	membrane
FORC6_RS04610	COG3101	peptidyl-lysine hydroxylation
FORC6_RS04620	COG0431	NADPH-dependent FMN reductase
FORC6_RS04625	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FORC6_RS04625	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FORC6_RS04630	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FORC6_RS04635	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FORC6_RS04640	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FORC6_RS04650	COG0101	tRNA pseudouridine synthase activity
FORC6_RS04655	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FORC6_RS04660	COG0285	dihydrofolate synthase activity
FORC6_RS04665	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
FORC6_RS04670	COG1286	toxin biosynthetic process
FORC6_RS04675	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FORC6_RS04680	COG0583	DNA-binding transcription factor activity
FORC6_RS04685	COG0745	RESPONSE REGULATOR receiver
FORC6_RS04690	COG2832	Protein of unknown function (DUF454)
FORC6_RS04695	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FORC6_RS04705	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FORC6_RS04710	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FORC6_RS04715	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FORC6_RS04720	COG0814	amino acid
FORC6_RS04725	COG0251	oxidation-reduction process
FORC6_RS04730	COG3681	Belongs to the UPF0597 family
FORC6_RS04745	COG2261	transglycosylase associated protein
FORC6_RS04750	COG2983	Belongs to the UPF0260 family
FORC6_RS04755	COG0668	transmembrane transport
FORC6_RS04765	COG0346	lactoylglutathione lyase activity
FORC6_RS04775	COG1785	Belongs to the alkaline phosphatase family
FORC6_RS04790	COG2226	methyltransferase
FORC6_RS04805	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FORC6_RS04810	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FORC6_RS04820	COG3139	Protein of unknown function (DUF1315)
FORC6_RS04825	COG0252	asparaginase activity
FORC6_RS04830	COG0616	signal peptide processing
FORC6_RS04835	COG0446	pyridine nucleotide-disulphide oxidoreductase
FORC6_RS04835	COG1902	pentaerythritol trinitrate reductase activity
FORC6_RS04840	COG0778	Nitroreductase
FORC6_RS04845	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FORC6_RS04860	COG0123	including yeast histone deacetylase and acetoin utilization protein
FORC6_RS04870	COG3083	sulfuric ester hydrolase activity
FORC6_RS04875	COG3082	Protein of unknown function (DUF1414)
FORC6_RS04880	COG3081	Nucleoid-associated protein
FORC6_RS04895	COG1757	Na H antiporter
FORC6_RS04900	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FORC6_RS04905	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FORC6_RS04910	COG2095	MarC family integral membrane protein
FORC6_RS04915	COG1012	belongs to the aldehyde dehydrogenase family
FORC6_RS04915	COG1454	alcohol dehydrogenase
FORC6_RS04935	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FORC6_RS04945	COG2056	Na+-H+ antiporter family
FORC6_RS04950	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FORC6_RS04955	COG2885	chlorophyll binding
FORC6_RS04965	COG0346	lactoylglutathione lyase activity
FORC6_RS04970	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FORC6_RS04975	COG4660	Part of a membrane complex involved in electron transport
FORC6_RS04980	COG4659	FMN binding
FORC6_RS04985	COG4658	electron transport chain
FORC6_RS04990	COG4656	Part of a membrane complex involved in electron transport
FORC6_RS04995	COG2878	Part of a membrane complex involved in electron transport
FORC6_RS05000	COG4657	Part of a membrane complex involved in electron transport
FORC6_RS05010	COG0708	Exodeoxyribonuclease III
FORC6_RS05020	COG3923	Primosomal replication protein n
FORC6_RS05025	COG0730	response to heat
FORC6_RS05030	COG1199	ATP-dependent helicase activity
FORC6_RS05040	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
FORC6_RS05045	COG1187	pseudouridine synthase activity
FORC6_RS05055	COG1278	Cold shock
FORC6_RS05060	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FORC6_RS05065	COG0542	response to heat
FORC6_RS05075	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FORC6_RS05080	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FORC6_RS05085	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FORC6_RS05095	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FORC6_RS05105	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FORC6_RS05110	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FORC6_RS05115	COG0297	glycogen (starch) synthase activity
FORC6_RS05135	COG3070	regulator of competence-specific genes
FORC6_RS05140	COG1609	Transcriptional regulator
FORC6_RS05145	COG3381	protein complex oligomerization
FORC6_RS05150	COG0745	RESPONSE REGULATOR receiver
FORC6_RS05155	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FORC6_RS05160	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FORC6_RS05165	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
FORC6_RS05170	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
FORC6_RS05175	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FORC6_RS05190	COG4067	protein conserved in archaea
FORC6_RS05190	COG0189	ligase activity
FORC6_RS05195	COG0500	methyltransferase
FORC6_RS05200	COG4106	trans-aconitate 2-methyltransferase activity
FORC6_RS05205	COG1801	Protein of unknown function DUF72
FORC6_RS05210	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FORC6_RS05215	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FORC6_RS05220	COG0840	transmembrane signaling receptor activity
FORC6_RS05225	COG0632	four-way junction helicase activity
FORC6_RS05230	COG2255	four-way junction helicase activity
FORC6_RS05235	COG1271	oxidase subunit
FORC6_RS05240	COG1294	oxidase, subunit
FORC6_RS05245	COG4890	Cyd operon protein YbgT
FORC6_RS05255	COG0824	Thioesterase
FORC6_RS05260	COG0811	peptide transport
FORC6_RS05275	COG0823	Involved in the tonB-independent uptake of proteins
FORC6_RS05280	COG2885	chlorophyll binding
FORC6_RS05285	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
FORC6_RS05290	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FORC6_RS05295	COG3318	Belongs to the UPF0149 family
FORC6_RS05295	COG3012	SEC-C Motif Domain Protein
FORC6_RS05300	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FORC6_RS05305	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FORC6_RS05310	COG2186	Transcriptional regulator
FORC6_RS05320	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FORC6_RS05320	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FORC6_RS05325	COG0489	protein tyrosine kinase activity
FORC6_RS05330	COG0572	uridine kinase
FORC6_RS05340	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
FORC6_RS05345	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FORC6_RS05350	COG0659	secondary active sulfate transmembrane transporter activity
FORC6_RS05355	COG1530	ribonuclease E activity
FORC6_RS05360	COG0564	pseudouridine synthase activity
FORC6_RS05365	COG0424	maF-like protein
FORC6_RS05370	COG1399	metal-binding, possibly nucleic acid-binding protein
FORC6_RS05380	COG0416	fatty acid biosynthetic process
FORC6_RS05385	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FORC6_RS05415	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FORC6_RS05420	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FORC6_RS05430	COG0084	hydrolase, TatD family'
FORC6_RS05435	COG1263	PTS System
FORC6_RS05435	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC6_RS05445	COG0733	neurotransmitter:sodium symporter activity
FORC6_RS05455	COG4667	esterase of the alpha-beta hydrolase superfamily
FORC6_RS05460	COG0469	pyruvate kinase activity
FORC6_RS05465	COG1940	carbohydrate kinase activity
FORC6_RS05470	COG0784	Response regulator, receiver
FORC6_RS05470	COG0835	chemotaxis
FORC6_RS05475	COG0587	DNA-directed DNA polymerase activity
FORC6_RS05490	COG1028	Short-chain dehydrogenase reductase Sdr
FORC6_RS05495	COG0616	signal peptide processing
FORC6_RS05500	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FORC6_RS05505	COG0539	negative regulation of cytoplasmic translation
FORC6_RS05515	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
FORC6_RS05520	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
FORC6_RS05525	COG0284	orotidine-5'-phosphate decarboxylase activity
FORC6_RS05530	COG4166	transmembrane transport
FORC6_RS05555	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FORC6_RS05565	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FORC6_RS05565	COG3008	intermembrane lipid transfer
FORC6_RS05570	COG2995	paraquat-inducible protein a
FORC6_RS05575	COG3258	Cytochrome c
FORC6_RS05580	COG2863	cytochrome
FORC6_RS05620	COG4232	protein-disulfide reductase activity
FORC6_RS05625	COG3118	belongs to the thioredoxin family
FORC6_RS05645	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FORC6_RS05655	COG0577	efflux transmembrane transporter activity
FORC6_RS05655	COG1136	(ABC) transporter
FORC6_RS05660	COG1136	(ABC) transporter
FORC6_RS05660	COG0577	efflux transmembrane transporter activity
FORC6_RS05665	COG1136	(ABC) transporter
FORC6_RS05665	COG0577	efflux transmembrane transporter activity
FORC6_RS05670	COG1335	isochorismatase
FORC6_RS05690	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FORC6_RS05715	COG2116	formate transmembrane transporter activity
FORC6_RS05720	COG0390	transport system, permease component
FORC6_RS05725	COG4459	periplasmic nitrate reductase
FORC6_RS05730	COG3005	denitrification pathway
FORC6_RS05735	COG0243	molybdopterin cofactor binding
FORC6_RS05750	COG1227	inorganic diphosphatase activity
FORC6_RS05760	COG4172	Belongs to the ABC transporter superfamily
FORC6_RS05770	COG4171	peptide transport system, permease
FORC6_RS05785	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
FORC6_RS05790	COG1842	Phage shock protein A
FORC6_RS05800	COG1983	PspC domain protein
FORC6_RS05805	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FORC6_RS05820	COG0519	Catalyzes the synthesis of GMP from XMP
FORC6_RS05825	COG5380	lipid catabolic process
FORC6_RS05830	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
FORC6_RS05835	COG0626	cystathionine gamma-synthase activity
FORC6_RS05845	COG0733	neurotransmitter:sodium symporter activity
FORC6_RS05855	COG0564	pseudouridine synthase activity
FORC6_RS05865	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FORC6_RS05870	COG1151	hydroxylamine reductase activity
FORC6_RS05875	COG3604	Transcriptional regulator
FORC6_RS05885	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FORC6_RS05890	COG4136	ATPase activity
FORC6_RS05895	COG4135	transport system, permease component
FORC6_RS05900	COG4134	Bacterial extracellular solute-binding protein
FORC6_RS05905	COG0398	Pfam SNARE associated Golgi protein
FORC6_RS05915	COG0493	'glutamate synthase
FORC6_RS05940	COG3313	Fe-S protein
FORC6_RS05965	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FORC6_RS05985	COG1061	Type III restriction enzyme res subunit
FORC6_RS05990	COG1187	pseudouridine synthase activity
FORC6_RS05995	COG2814	Major facilitator Superfamily
FORC6_RS06025	COG3005	denitrification pathway
FORC6_RS06030	COG0702	epimerase
FORC6_RS06035	COG0534	Mate efflux family protein
FORC6_RS06040	COG4181	ATPase activity
FORC6_RS06055	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FORC6_RS06070	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FORC6_RS06075	COG3273	potassium ion transport
FORC6_RS06075	COG2985	domain, Protein
FORC6_RS06080	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FORC6_RS06090	COG1737	Transcriptional regulator
FORC6_RS06095	COG0076	glutamate decarboxylase activity
FORC6_RS06105	COG2431	L-lysine efflux transmembrane transporter activity
FORC6_RS06115	COG3070	regulator of competence-specific genes
FORC6_RS06130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC6_RS06130	COG4191	Histidine kinase
FORC6_RS06140	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FORC6_RS06145	COG3048	D-serine ammonia-lyase activity
FORC6_RS06150	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FORC6_RS06155	COG4988	ABC transporter
FORC6_RS06160	COG0492	ferredoxin-NADP+ reductase activity
FORC6_RS06185	COG0471	metal ion transport
FORC6_RS06190	COG2949	membrane
FORC6_RS06195	COG0281	malic enzyme
FORC6_RS06200	COG1643	Atp-dependent helicase
FORC6_RS06205	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
FORC6_RS06220	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FORC6_RS06255	COG0277	FAD linked oxidase domain protein
FORC6_RS06255	COG0247	lactate metabolic process
FORC6_RS06270	COG2986	histidine ammonia-lyase
FORC6_RS06275	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FORC6_RS06280	COG0010	Belongs to the arginase family
FORC6_RS06285	COG1228	amidohydrolase
FORC6_RS06290	COG2188	Transcriptional regulator
FORC6_RS06305	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FORC6_RS06315	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FORC6_RS06325	COG0393	Putative heavy-metal-binding
FORC6_RS06355	COG3706	GGDEF domain
FORC6_RS06360	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FORC6_RS06365	COG0072	phenylalanine-tRNA ligase activity
FORC6_RS06365	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FORC6_RS06375	COG0776	regulation of translation
FORC6_RS06385	COG0500	methyltransferase
FORC6_RS06390	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
FORC6_RS06395	COG0295	cytidine deaminase activity
FORC6_RS06400	COG1346	cytolysis
FORC6_RS06405	COG1380	Effector of murein hydrolase LrgA
FORC6_RS06410	COG2925	Exonuclease
FORC6_RS06415	COG1823	symporter activity
FORC6_RS06420	COG0702	epimerase
FORC6_RS06425	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FORC6_RS06430	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FORC6_RS06450	COG2988	succinylglutamate desuccinylase activity
FORC6_RS06455	COG4139	cobalamin transport
FORC6_RS06460	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
FORC6_RS06480	COG0583	DNA-binding transcription factor activity
FORC6_RS06500	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FORC6_RS06505	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FORC6_RS06510	COG3475	LICD family
FORC6_RS06515	COG1451	nucleotide metabolic process
FORC6_RS06520	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
FORC6_RS06550	COG3938	Belongs to the proline racemase family
FORC6_RS06565	COG2423	ornithine cyclodeaminase activity
FORC6_RS06570	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FORC6_RS06575	COG3842	ATPase activity
FORC6_RS06580	COG1176	ABC-type spermidine putrescine transport system, permease component I
FORC6_RS06585	COG1177	transmembrane transport
FORC6_RS06595	COG3291	Pkd domain containing protein
FORC6_RS06610	COG0444	Belongs to the ABC transporter superfamily
FORC6_RS06615	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FORC6_RS06620	COG0601	transmembrane transport
FORC6_RS06630	COG2195	Cleaves the N-terminal amino acid of tripeptides
FORC6_RS06645	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
FORC6_RS06655	COG0625	glutathione transferase activity
FORC6_RS06695	COG1280	lysine exporter protein (LysE YggA)
FORC6_RS06700	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC6_RS06720	COG1757	Na H antiporter
FORC6_RS06725	COG0174	glutamine synthetase
FORC6_RS06730	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FORC6_RS06735	COG1917	Cupin 2, conserved barrel domain protein
FORC6_RS06735	COG1396	sequence-specific DNA binding
FORC6_RS06740	COG1012	belongs to the aldehyde dehydrogenase family
FORC6_RS06745	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FORC6_RS06755	COG2957	Belongs to the agmatine deiminase family
FORC6_RS06760	COG1012	belongs to the aldehyde dehydrogenase family
FORC6_RS06765	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FORC6_RS06770	COG1227	inorganic diphosphatase activity
FORC6_RS06775	COG2200	EAL domain
FORC6_RS06775	COG2771	luxR family
FORC6_RS06790	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FORC6_RS06805	COG1846	Transcriptional regulator
FORC6_RS06810	COG2315	Protein conserved in bacteria
FORC6_RS06830	COG0110	maltose O-acetyltransferase activity
FORC6_RS06860	COG3063	Type IV pilus biogenesis stability protein PilW
FORC6_RS06865	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FORC6_RS06875	COG0531	amino acid
FORC6_RS06880	COG1560	Kdo2-lipid A biosynthetic process
FORC6_RS06885	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
FORC6_RS06890	COG1280	lysine exporter protein (LysE YggA)
FORC6_RS06900	COG1115	amino acid carrier protein
FORC6_RS06920	COG1368	sulfuric ester hydrolase activity
FORC6_RS06925	COG0642	Histidine kinase
FORC6_RS06930	COG0745	RESPONSE REGULATOR receiver
FORC6_RS06940	COG1028	Short-chain dehydrogenase reductase Sdr
FORC6_RS06960	COG2113	Glycine betaine
FORC6_RS06965	COG4176	ABC-type proline glycine betaine transport system permease component
FORC6_RS06985	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FORC6_RS06990	COG0456	acetyltransferase
FORC6_RS06995	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FORC6_RS07000	COG0662	Cupin 2, conserved barrel domain protein
FORC6_RS07005	COG0527	aspartate kinase activity
FORC6_RS07020	COG1858	cytochrome C peroxidase
FORC6_RS07035	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FORC6_RS07050	COG3290	protein histidine kinase activity
FORC6_RS07055	COG4565	transcriptional regulatory protein
FORC6_RS07060	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FORC6_RS07065	COG0363	glucosamine-6-phosphate deaminase activity
FORC6_RS07070	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FORC6_RS07085	COG3284	Transcriptional regulator
FORC6_RS07090	COG1012	belongs to the aldehyde dehydrogenase family
FORC6_RS07160	COG4669	(LipO)protein
FORC6_RS07180	COG3177	Filamentation induced by cAMP protein fic
FORC6_RS07210	COG1073	alpha beta
FORC6_RS07215	COG1073	alpha beta
FORC6_RS07225	COG4792	protein secretion
FORC6_RS07230	COG4791	protein targeting
FORC6_RS07235	COG4794	Type iii secretion
FORC6_RS07240	COG4790	Type iii secretion
FORC6_RS07310	COG0457	Tetratricopeptide repeat
FORC6_RS07330	COG0730	response to heat
FORC6_RS07360	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FORC6_RS07365	COG0372	Belongs to the citrate synthase family
FORC6_RS07375	COG2828	Protein conserved in bacteria
FORC6_RS07400	COG0561	phosphatase activity
FORC6_RS07405	COG0602	queuosine metabolic process
FORC6_RS07410	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FORC6_RS07415	COG3706	GGDEF domain
FORC6_RS07455	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FORC6_RS07460	COG0840	transmembrane signaling receptor activity
FORC6_RS07465	COG1254	Belongs to the acylphosphatase family
FORC6_RS07470	COG2920	part of a sulfur-relay system
FORC6_RS07480	COG0670	Belongs to the BI1 family
FORC6_RS07485	COG1126	abc transporter atp-binding protein
FORC6_RS07490	COG0765	amino acid transport
FORC6_RS07495	COG4597	amino acid ABC transporter
FORC6_RS07500	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC6_RS07510	COG1666	GTP binding
FORC6_RS07515	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FORC6_RS07535	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FORC6_RS07535	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
FORC6_RS07540	COG3008	intermembrane lipid transfer
FORC6_RS07545	COG2995	paraquat-inducible protein a
FORC6_RS07550	COG1132	(ABC) transporter
FORC6_RS07555	COG1956	GAF domain-containing protein
FORC6_RS07560	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
FORC6_RS07575	COG0308	aminopeptidase N
FORC6_RS07580	COG2902	Dehydrogenase
FORC6_RS07585	COG0167	dihydroorotate dehydrogenase activity
FORC6_RS07605	COG0488	(ABC) transporter
FORC6_RS07620	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FORC6_RS07625	COG1067	ATP-dependent peptidase activity
FORC6_RS07630	COG3120	sequence-specific DNA binding
FORC6_RS07735	COG2205	protein histidine kinase activity
FORC6_RS07735	COG0784	Response regulator, receiver
FORC6_RS07750	COG3278	Belongs to the heme-copper respiratory oxidase family
FORC6_RS07765	COG2010	Cytochrome c
FORC6_RS07775	COG2217	Heavy metal translocating P-type atpase
FORC6_RS07790	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FORC6_RS07795	COG0589	response to stress
FORC6_RS07800	COG0037	tRNA processing
FORC6_RS07820	COG3842	ATPase activity
FORC6_RS07830	COG1177	transmembrane transport
FORC6_RS07840	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FORC6_RS07845	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FORC6_RS07855	COG0004	ammonium transporteR
FORC6_RS07915	COG3209	COG3209 Rhs family protein
FORC6_RS07930	COG0437	4 iron, 4 sulfur cluster binding
FORC6_RS07935	COG0243	molybdopterin cofactor binding
FORC6_RS07935	COG3383	formate dehydrogenase (NAD+) activity
FORC6_RS07945	COG3381	protein complex oligomerization
FORC6_RS07965	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FORC6_RS07970	COG0488	(ABC) transporter
FORC6_RS07975	COG4191	Histidine kinase
FORC6_RS07980	COG2204	response regulator
FORC6_RS07995	COG3842	ATPase activity
FORC6_RS08000	COG0746	molybdenum cofactor guanylyltransferase activity
FORC6_RS08015	COG0438	transferase activity, transferring glycosyl groups
FORC6_RS08020	COG1215	transferase activity, transferring glycosyl groups
FORC6_RS08025	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FORC6_RS08035	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FORC6_RS08050	COG1643	Atp-dependent helicase
FORC6_RS08055	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FORC6_RS08070	COG3302	dmso reductase anchor subunit
FORC6_RS08075	COG0437	4 iron, 4 sulfur cluster binding
FORC6_RS08080	COG0243	molybdopterin cofactor binding
FORC6_RS08120	COG0443	Heat shock 70 kDa protein
FORC6_RS08125	COG0443	Heat shock 70 kDa protein
FORC6_RS08145	COG4968	Prepilin-type N-terminal cleavage methylation domain
FORC6_RS08150	COG1132	(ABC) transporter
FORC6_RS08155	COG1132	(ABC) transporter
FORC6_RS08175	COG0814	amino acid
FORC6_RS08185	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FORC6_RS08195	COG0861	Integral membrane protein TerC family
FORC6_RS08205	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FORC6_RS08210	COG1328	CTP reductase activity
FORC6_RS08215	COG1280	lysine exporter protein (LysE YggA)
FORC6_RS08225	COG3300	MHYT domain
FORC6_RS08225	COG5001	Diguanylate cyclase
FORC6_RS08235	COG4191	Histidine kinase
FORC6_RS08235	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC6_RS08240	COG0471	metal ion transport
FORC6_RS08270	COG1940	carbohydrate kinase activity
FORC6_RS08275	COG3148	PFAM DTW domain containing protein
FORC6_RS08310	COG3290	protein histidine kinase activity
FORC6_RS08310	COG0840	transmembrane signaling receptor activity
FORC6_RS08315	COG0791	NLP P60 protein
FORC6_RS08325	COG3706	GGDEF domain
FORC6_RS08330	COG2201	protein-glutamate methylesterase activity
FORC6_RS08335	COG3001	Fructosamine kinase
FORC6_RS08345	COG0307	riboflavin synthase, alpha
FORC6_RS08350	COG0534	Mate efflux family protein
FORC6_RS08360	COG1793	dna ligase
FORC6_RS08390	COG2204	response regulator
FORC6_RS08545	COG0346	lactoylglutathione lyase activity
FORC6_RS08595	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FORC6_RS08740	COG0456	acetyltransferase
FORC6_RS08775	COG0346	lactoylglutathione lyase activity
FORC6_RS08785	COG1683	Conserved Protein
FORC6_RS08940	COG0456	acetyltransferase
FORC6_RS09055	COG1335	isochorismatase
FORC6_RS09120	COG2732	(Barnase) inhibitor
FORC6_RS09180	COG2026	Addiction module toxin, RelE StbE family
FORC6_RS09545	COG0346	lactoylglutathione lyase activity
FORC6_RS09665	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC6_RS09675	COG3768	UPF0283 membrane protein
FORC6_RS09680	COG3106	COG3106 Predicted ATPase
FORC6_RS09695	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FORC6_RS09700	COG0784	Response regulator, receiver
FORC6_RS09700	COG2205	protein histidine kinase activity
FORC6_RS09710	COG0494	nUDIX hydrolase
FORC6_RS09715	COG0814	amino acid
FORC6_RS09720	COG1760	l-serine dehydratase
FORC6_RS09725	COG2200	EAL domain
FORC6_RS09735	COG0720	synthase
FORC6_RS09755	COG1278	Cold shock
FORC6_RS09760	COG0557	exoribonuclease II activity
FORC6_RS09775	COG0840	transmembrane signaling receptor activity
FORC6_RS09780	COG0017	Asparaginyl-tRNA synthetase
FORC6_RS09790	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FORC6_RS09805	COG1448	Aminotransferase
FORC6_RS09825	COG0840	transmembrane signaling receptor activity
FORC6_RS09830	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FORC6_RS09835	COG1846	Transcriptional regulator
FORC6_RS09860	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FORC6_RS09875	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FORC6_RS09880	COG3108	Peptidase M15
FORC6_RS09885	COG2989	Protein conserved in bacteria
FORC6_RS09910	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FORC6_RS09920	COG4235	cytochrome complex assembly
FORC6_RS09920	COG3088	subunit of a heme lyase
FORC6_RS09930	COG1138	Cytochrome C-type biogenesis protein
FORC6_RS09935	COG3301	Polysulphide reductase, NrfD
FORC6_RS09940	COG0437	4 iron, 4 sulfur cluster binding
FORC6_RS09950	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
FORC6_RS09970	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FORC6_RS09975	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FORC6_RS09980	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FORC6_RS10005	COG0019	diaminopimelate decarboxylase activity
FORC6_RS10045	COG0322	excinuclease ABC activity
FORC6_RS10050	COG2197	response regulator
FORC6_RS10055	COG0417	DNA replication proofreading
FORC6_RS10065	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FORC6_RS10070	COG3099	Belongs to the UPF0263 family
FORC6_RS10075	COG1187	pseudouridine synthase activity
FORC6_RS10085	COG0009	L-threonylcarbamoyladenylate synthase
FORC6_RS10090	COG0613	PHP domain protein
FORC6_RS10100	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FORC6_RS10105	COG0512	Glutamine amidotransferase of anthranilate synthase
FORC6_RS10110	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FORC6_RS10115	COG0135	phosphoribosylanthranilate isomerase activity
FORC6_RS10115	COG0134	indole-3-glycerol-phosphate synthase activity
FORC6_RS10120	COG0133	tryptophan synthase activity
FORC6_RS10125	COG0159	tryptophan synthase activity
FORC6_RS10130	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FORC6_RS10135	COG0318	PFAM AMP-dependent synthetase and ligase
FORC6_RS10140	COG1301	dicarboxylic acid transport
FORC6_RS10160	COG2917	probably involved in intracellular septation
FORC6_RS10170	COG2350	Protein conserved in bacteria
FORC6_RS10180	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FORC6_RS10185	COG0583	DNA-binding transcription factor activity
FORC6_RS10200	COG3706	GGDEF domain
FORC6_RS10200	COG4251	negative regulation of phosphorylation
FORC6_RS10200	COG5001	Diguanylate cyclase
FORC6_RS10200	COG2203	Gaf domain
FORC6_RS10205	COG1032	radical SAM domain protein
FORC6_RS10210	COG0840	transmembrane signaling receptor activity
FORC6_RS10215	COG0745	RESPONSE REGULATOR receiver
FORC6_RS10220	COG3850	Histidine kinase
FORC6_RS10220	COG5002	protein histidine kinase activity
FORC6_RS10260	COG1435	thymidine kinase activity
FORC6_RS10265	COG0215	cysteine-tRNA ligase activity
FORC6_RS10270	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FORC6_RS10275	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FORC6_RS10280	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FORC6_RS10285	COG3012	SEC-C Motif Domain Protein
FORC6_RS10290	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FORC6_RS10290	COG0140	phosphoribosyl-ATP diphosphatase activity
FORC6_RS10295	COG0107	imidazoleglycerol-phosphate synthase activity
FORC6_RS10300	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FORC6_RS10305	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FORC6_RS10310	COG0131	Imidazoleglycerol-phosphate dehydratase
FORC6_RS10310	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FORC6_RS10315	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FORC6_RS10320	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FORC6_RS10325	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FORC6_RS10340	COG1757	Na H antiporter
FORC6_RS10350	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FORC6_RS10360	COG0482	sulfurtransferase activity
FORC6_RS10365	COG2915	High frequency lysogenization protein hflD homolog
FORC6_RS10370	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FORC6_RS10390	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FORC6_RS10405	COG1028	Short-chain dehydrogenase reductase Sdr
FORC6_RS10420	COG0501	Belongs to the peptidase M48B family
FORC6_RS10425	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FORC6_RS10435	COG0156	8-amino-7-oxononanoate synthase activity
FORC6_RS10440	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FORC6_RS10445	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FORC6_RS10450	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FORC6_RS10465	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FORC6_RS10470	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FORC6_RS10475	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FORC6_RS10480	COG1674	ftsk spoiiie
FORC6_RS10490	COG0686	Belongs to the AlaDH PNT family
FORC6_RS10500	COG0583	DNA-binding transcription factor activity
FORC6_RS10515	COG3568	Endonuclease Exonuclease Phosphatase
FORC6_RS10540	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FORC6_RS10545	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FORC6_RS10550	COG0840	transmembrane signaling receptor activity
FORC6_RS10565	COG0784	Response regulator, receiver
FORC6_RS10565	COG5002	protein histidine kinase activity
FORC6_RS10575	COG0754	glutathionylspermidine amidase activity
FORC6_RS10585	COG3766	membrane
FORC6_RS10595	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FORC6_RS10605	COG0366	Alpha amylase catalytic
FORC6_RS10610	COG1122	ATPase activity
FORC6_RS10615	COG4120	Belongs to the binding-protein-dependent transport system permease family
FORC6_RS10625	COG3092	negative regulation of chromosome organization
FORC6_RS10630	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FORC6_RS10635	COG0280	phosphate acetyltransferase
FORC6_RS10635	COG0857	belongs to the CobB CobQ family
FORC6_RS10640	COG3174	membrane
FORC6_RS10650	COG0435	Glutathione S-transferase
FORC6_RS10660	COG0444	Belongs to the ABC transporter superfamily
FORC6_RS10665	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FORC6_RS10670	COG0601	transmembrane transport
FORC6_RS10680	COG0314	molybdopterin synthase activity
FORC6_RS10685	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FORC6_RS10690	COG0315	cyclic pyranopterin monophosphate synthase activity
FORC6_RS10695	COG0521	Mo-molybdopterin cofactor biosynthetic process
FORC6_RS10700	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FORC6_RS10705	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FORC6_RS10710	COG2198	Histidine kinase
FORC6_RS10715	COG2204	response regulator
FORC6_RS10720	COG0556	nucleotide-excision repair
FORC6_RS10765	COG1882	Formate acetyltransferase
FORC6_RS10775	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FORC6_RS10785	COG3013	Belongs to the UPF0304 family
FORC6_RS10790	COG2766	serine protein kinase
FORC6_RS10795	COG2718	Belongs to the UPF0229 family
FORC6_RS10800	COG2719	SpoVR family
FORC6_RS10805	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FORC6_RS10815	COG1663	tetraacyldisaccharide 4'-kinase activity
FORC6_RS10820	COG1132	(ABC) transporter
FORC6_RS10825	COG2333	competence protein COMEC
FORC6_RS10825	COG0658	competence protein
FORC6_RS10835	COG4591	ABC-type transport system involved in lipoprotein release permease component
FORC6_RS10840	COG1136	(ABC) transporter
FORC6_RS10845	COG4591	ABC-type transport system involved in lipoprotein release permease component
FORC6_RS10855	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FORC6_RS10870	COG1252	NADH dehydrogenase
FORC6_RS10875	COG3150	esterase
FORC6_RS10900	COG0537	adenosine 5'-monophosphoramidase activity
FORC6_RS10925	COG0517	IMP dehydrogenase activity
FORC6_RS10925	COG0516	GMP reductase activity
FORC6_RS10930	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
FORC6_RS10935	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FORC6_RS10940	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FORC6_RS10950	COG2199	diguanylate cyclase activity
FORC6_RS10965	COG3126	Type III secretion system lipoprotein chaperone (YscW)
FORC6_RS10970	COG1946	Acyl-CoA thioesterase
FORC6_RS10980	COG1522	sequence-specific DNA binding
FORC6_RS11005	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FORC6_RS11010	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FORC6_RS11055	COG0477	Major facilitator Superfamily
FORC6_RS11060	COG2855	membrane
FORC6_RS11080	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FORC6_RS11085	COG0596	Alpha beta hydrolase
FORC6_RS11090	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
FORC6_RS11095	COG1169	isochorismate synthase
FORC6_RS11100	COG0436	Aminotransferase
FORC6_RS11105	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
FORC6_RS11110	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FORC6_RS11125	COG1555	photosystem II stabilization
FORC6_RS11130	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FORC6_RS11135	COG0776	regulation of translation
FORC6_RS11140	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FORC6_RS11145	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FORC6_RS11155	COG0544	peptidyl-prolyl cis-trans isomerase activity
FORC6_RS11170	COG2204	response regulator
FORC6_RS11180	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FORC6_RS11185	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FORC6_RS11190	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FORC6_RS11195	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FORC6_RS11210	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FORC6_RS11215	COG0569	domain protein
FORC6_RS11220	COG0513	Belongs to the DEAD box helicase family
FORC6_RS11225	COG1253	flavin adenine dinucleotide binding
FORC6_RS11260	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FORC6_RS11265	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FORC6_RS11280	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FORC6_RS11285	COG1216	Glycosyl transferase, family 2
FORC6_RS11290	COG2986	histidine ammonia-lyase
FORC6_RS11315	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FORC6_RS11325	COG1028	Short-chain dehydrogenase reductase Sdr
FORC6_RS11405	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FORC6_RS11410	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FORC6_RS11415	COG0583	DNA-binding transcription factor activity
FORC6_RS11420	COG2951	lytic endotransglycosylase activity
FORC6_RS11425	COG3100	YcgL domain-containing protein
FORC6_RS11430	COG0850	regulation of cytokinetic process
FORC6_RS11435	COG2894	cell division
FORC6_RS11440	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FORC6_RS11445	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FORC6_RS11450	COG0318	PFAM AMP-dependent synthetase and ligase
FORC6_RS11455	COG2267	carboxylic ester hydrolase activity
FORC6_RS11470	COG1214	PFAM Peptidase M22, glycoprotease
FORC6_RS11475	COG1199	ATP-dependent helicase activity
FORC6_RS11480	COG0788	formyltetrahydrofolate deformylase activity
FORC6_RS11495	COG3102	Protein conserved in bacteria
FORC6_RS11500	COG0018	arginyl-trna synthetase
FORC6_RS11520	COG1918	ferrous iron import across plasma membrane
FORC6_RS11525	COG4977	sequence-specific DNA binding
FORC6_RS11530	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
FORC6_RS11535	COG1121	(ABC) transporter
FORC6_RS11540	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FORC6_RS11545	COG0121	glutamine amidotransferase
FORC6_RS11550	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FORC6_RS11555	COG1960	acyl-CoA dehydrogenase activity
FORC6_RS11570	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FORC6_RS11575	COG0328	RNA-DNA hybrid ribonuclease activity
FORC6_RS11580	COG2226	methyltransferase
FORC6_RS11585	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FORC6_RS11590	COG1388	LysM domain
FORC6_RS11590	COG0741	lytic transglycosylase activity
FORC6_RS11600	COG3021	interspecies interaction between organisms
FORC6_RS11605	COG0347	Belongs to the P(II) protein family
FORC6_RS11615	COG0037	tRNA processing
FORC6_RS11620	COG0825	malonyl-CoA metabolic process
FORC6_RS11625	COG0587	DNA-directed DNA polymerase activity
FORC6_RS11640	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FORC6_RS11645	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FORC6_RS11650	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FORC6_RS11655	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
FORC6_RS11665	COG0750	zinc metalloprotease
FORC6_RS11670	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FORC6_RS11675	COG0575	Belongs to the CDS family
FORC6_RS11680	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FORC6_RS11685	COG0233	cytoplasmic translational termination
FORC6_RS11690	COG0528	UMP kinase activity
FORC6_RS11695	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FORC6_RS11700	COG0052	Belongs to the universal ribosomal protein uS2 family
FORC6_RS11705	COG0024	Methionine aminopeptidase
FORC6_RS11710	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FORC6_RS11720	COG0564	pseudouridine synthase activity
FORC6_RS11725	COG3098	single-species biofilm formation
FORC6_RS11745	COG1671	Belongs to the UPF0178 family
FORC6_RS11750	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
FORC6_RS11755	COG0254	rRNA binding
FORC6_RS11760	COG1720	tRNA m6t6A37 methyltransferase activity
FORC6_RS11765	COG0442	prolyl-tRNA aminoacylation
FORC6_RS11785	COG0733	neurotransmitter:sodium symporter activity
FORC6_RS11800	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FORC6_RS11805	COG0514	ATP-dependent DNA helicase (RecQ)
FORC6_RS11810	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FORC6_RS11825	COG1477	protein flavinylation
FORC6_RS11830	COG2871	sodium ion transport
FORC6_RS11835	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FORC6_RS11840	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FORC6_RS11845	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FORC6_RS11850	COG1805	sodium ion transport
FORC6_RS11855	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FORC6_RS11865	COG0271	Belongs to the BolA IbaG family
FORC6_RS11870	COG2813	Specifically methylates the guanine in position
FORC6_RS11875	COG3056	Lipoprotein
FORC6_RS11895	COG1595	DNA-templated transcription, initiation
FORC6_RS11915	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FORC6_RS11920	COG0693	protein deglycase activity
FORC6_RS11925	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FORC6_RS11930	COG3706	GGDEF domain
FORC6_RS11935	COG2166	iron-sulfur cluster assembly
FORC6_RS11940	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FORC6_RS11945	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FORC6_RS11955	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FORC6_RS11955	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FORC6_RS11970	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FORC6_RS11975	COG1074	ATP-dependent DNA helicase activity
FORC6_RS11985	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FORC6_RS12005	COG3141	response to X-ray
FORC6_RS12010	COG2171	N-acyltransferase activity
FORC6_RS12015	COG0584	glycerophosphoryl diester phosphodiesterase
FORC6_RS12020	COG2271	Major facilitator Superfamily
FORC6_RS12025	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FORC6_RS12030	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FORC6_RS12035	COG1349	DNA-binding transcription factor activity
FORC6_RS12040	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FORC6_RS12045	COG0598	Magnesium transport protein CorA
FORC6_RS12060	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FORC6_RS12065	COG1609	Transcriptional regulator
FORC6_RS12070	COG2176	DNA-directed DNA polymerase activity
FORC6_RS12085	COG2017	converts alpha-aldose to the beta-anomer
FORC6_RS12090	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FORC6_RS12100	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FORC6_RS12105	COG1609	Transcriptional regulator
FORC6_RS12110	COG3250	beta-galactosidase activity
FORC6_RS12115	COG2731	YhcH YjgK YiaL family protein
FORC6_RS12120	COG0531	amino acid
FORC6_RS12125	COG0583	DNA-binding transcription factor activity
FORC6_RS12185	COG4964	Belongs to the GSP D family
FORC6_RS12210	COG2169	Transcriptional regulator
FORC6_RS12215	COG1022	Amp-dependent synthetase and ligase
FORC6_RS12225	COG0583	DNA-binding transcription factor activity
FORC6_RS12230	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FORC6_RS12235	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FORC6_RS12245	COG0560	Phosphoserine phosphatase
FORC6_RS12255	COG0813	purine-nucleoside phosphorylase activity
FORC6_RS12260	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FORC6_RS12265	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FORC6_RS12270	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FORC6_RS12275	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FORC6_RS12280	COG0084	hydrolase, TatD family'
FORC6_RS12290	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FORC6_RS12310	COG3153	acetyltransferase
FORC6_RS12315	COG3154	lipid carrier protein
FORC6_RS12325	COG0826	peptidase U32
FORC6_RS12330	COG0826	peptidase U32
FORC6_RS12335	COG0534	Mate efflux family protein
FORC6_RS12350	COG1185	polyribonucleotide nucleotidyltransferase activity
FORC6_RS12355	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FORC6_RS12360	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FORC6_RS12365	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FORC6_RS12370	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FORC6_RS12375	COG0195	Participates in both transcription termination and antitermination
FORC6_RS12380	COG0779	Required for maturation of 30S ribosomal subunits
FORC6_RS12395	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FORC6_RS12405	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FORC6_RS12410	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FORC6_RS12415	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FORC6_RS12420	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FORC6_RS12425	COG1534	Rna-binding protein
FORC6_RS12430	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FORC6_RS12435	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FORC6_RS12440	COG2027	D-alanyl-D-alanine carboxypeptidase
FORC6_RS12455	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
FORC6_RS12485	COG0484	heat shock protein binding
FORC6_RS12490	COG0443	Heat shock 70 kDa protein
FORC6_RS12500	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FORC6_RS12505	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FORC6_RS12515	COG0497	DNA recombination
FORC6_RS12520	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FORC6_RS12525	COG2914	Belongs to the UPF0125 (RnfH) family
FORC6_RS12530	COG2867	negative regulation of translational initiation
FORC6_RS12535	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FORC6_RS12580	COG0583	DNA-binding transcription factor activity
FORC6_RS12585	COG3153	acetyltransferase
FORC6_RS12585	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FORC6_RS12605	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FORC6_RS12610	COG2873	o-acetylhomoserine
FORC6_RS12640	COG1115	amino acid carrier protein
FORC6_RS12650	COG1584	GPR1 FUN34 yaaH family protein
FORC6_RS12660	COG1757	Na H antiporter
FORC6_RS12665	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FORC6_RS12665	COG0519	Catalyzes the synthesis of GMP from XMP
FORC6_RS12670	COG0516	GMP reductase activity
FORC6_RS12670	COG0517	IMP dehydrogenase activity
FORC6_RS12675	COG1570	exodeoxyribonuclease VII activity
FORC6_RS12690	COG1160	GTP binding
FORC6_RS12695	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FORC6_RS12700	COG2976	Protein conserved in bacteria
FORC6_RS12705	COG0124	histidyl-tRNA synthetase
FORC6_RS12710	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FORC6_RS12720	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FORC6_RS12725	COG0105	UTP biosynthetic process
FORC6_RS12730	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FORC6_RS12735	COG2975	iron-sulfur cluster assembly
FORC6_RS12740	COG0633	Ferredoxin
FORC6_RS12745	COG0443	Heat shock 70 kDa protein
FORC6_RS12750	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FORC6_RS12760	COG0822	iron-sulfur transferase activity
FORC6_RS12765	COG1104	cysteine desulfurase activity
FORC6_RS12780	COG0483	inositol monophosphate 1-phosphatase activity
FORC6_RS12785	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FORC6_RS12790	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FORC6_RS12795	COG1862	Preprotein translocase
FORC6_RS12800	COG0343	queuine tRNA-ribosyltransferase activity
FORC6_RS12805	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FORC6_RS12815	COG0517	IMP dehydrogenase activity
FORC6_RS12825	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FORC6_RS12830	COG0583	DNA-binding transcription factor activity
FORC6_RS12835	COG0450	alkyl hydroperoxide reductase
FORC6_RS12840	COG3142	Participates in the control of copper homeostasis
FORC6_RS12850	COG0704	Plays a role in the regulation of phosphate uptake
FORC6_RS12855	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FORC6_RS12860	COG0581	inorganic phosphate transmembrane transporter activity
FORC6_RS12870	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FORC6_RS12875	COG0248	Ppx GppA phosphatase
FORC6_RS12885	COG5002	protein histidine kinase activity
FORC6_RS12890	COG0745	RESPONSE REGULATOR receiver
FORC6_RS12895	COG2974	May be involved in recombination
FORC6_RS12900	COG0826	peptidase U32
FORC6_RS12905	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FORC6_RS12960	COG0542	response to heat
FORC6_RS12965	COG1496	oxidoreductase activity
FORC6_RS12970	COG0564	pseudouridine synthase activity
FORC6_RS12975	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FORC6_RS12980	COG0741	lytic transglycosylase activity
FORC6_RS12985	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FORC6_RS12990	COG0077	Prephenate dehydratase
FORC6_RS12990	COG1605	Chorismate mutase
FORC6_RS12995	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
FORC6_RS13000	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
FORC6_RS13010	COG0488	(ABC) transporter
FORC6_RS13025	COG0739	heme binding
FORC6_RS13030	COG1605	Chorismate mutase
FORC6_RS13030	COG0287	Prephenate dehydrogenase
FORC6_RS13035	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FORC6_RS13040	COG1472	Belongs to the glycosyl hydrolase 3 family
FORC6_RS13045	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FORC6_RS13050	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FORC6_RS13065	COG1966	Carbon starvation protein
FORC6_RS13070	COG3275	phosphorelay sensor kinase activity
FORC6_RS13075	COG3279	Response regulator of the LytR AlgR family
FORC6_RS13080	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FORC6_RS13085	COG1047	Peptidyl-prolyl cis-trans
FORC6_RS13090	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FORC6_RS13095	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FORC6_RS13100	COG0196	riboflavin kinase activity
FORC6_RS13105	COG0728	peptidoglycan biosynthetic process
FORC6_RS13110	COG0268	Binds directly to 16S ribosomal RNA
FORC6_RS13115	COG0640	Transcriptional regulator
FORC6_RS13120	COG0583	DNA-binding transcription factor activity
FORC6_RS13125	COG1283	sodium-dependent phosphate transmembrane transporter activity
FORC6_RS13135	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FORC6_RS13140	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FORC6_RS13145	COG0730	response to heat
FORC6_RS13155	COG0494	nUDIX hydrolase
FORC6_RS13160	COG3066	DNA modification
FORC6_RS13170	COG0667	Aldo Keto reductase
FORC6_RS13185	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FORC6_RS13195	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FORC6_RS13200	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FORC6_RS13205	COG4974	Belongs to the 'phage' integrase family
FORC6_RS13210	COG0716	FMN binding
FORC6_RS13220	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FORC6_RS13225	COG0513	Belongs to the DEAD box helicase family
FORC6_RS13230	COG3022	response to hydroperoxide
FORC6_RS13235	COG1115	amino acid carrier protein
FORC6_RS13250	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FORC6_RS13255	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
FORC6_RS13260	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
FORC6_RS13265	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FORC6_RS13270	COG0083	homoserine kinase activity
FORC6_RS13285	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FORC6_RS13295	COG0745	RESPONSE REGULATOR receiver
FORC6_RS13305	COG0784	Response regulator, receiver
FORC6_RS13305	COG2198	Histidine kinase
FORC6_RS13305	COG5002	protein histidine kinase activity
FORC6_RS13310	COG5001	Diguanylate cyclase
FORC6_RS13310	COG4251	negative regulation of phosphorylation
FORC6_RS13310	COG3706	GGDEF domain
FORC6_RS13310	COG2203	Gaf domain
FORC6_RS13315	COG1242	4 iron, 4 sulfur cluster binding
FORC6_RS13320	COG0069	glutamate synthase activity
FORC6_RS13320	COG0070	glutamate synthase
FORC6_RS13320	COG0067	glutamate synthase
FORC6_RS13330	COG0069	glutamate synthase activity
FORC6_RS13330	COG0067	glutamate synthase
FORC6_RS13330	COG0070	glutamate synthase
FORC6_RS13335	COG0493	'glutamate synthase
FORC6_RS13345	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FORC6_RS13355	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FORC6_RS13360	COG2860	membrane
FORC6_RS13365	COG0583	DNA-binding transcription factor activity
FORC6_RS13380	COG0730	response to heat
FORC6_RS13395	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FORC6_RS13400	COG0505	Belongs to the CarA family
FORC6_RS13405	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FORC6_RS13410	COG0494	nUDIX hydrolase
FORC6_RS13415	COG0653	protein targeting
FORC6_RS13425	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
FORC6_RS13430	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FORC6_RS13435	COG0849	cell division
FORC6_RS13440	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FORC6_RS13445	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FORC6_RS13450	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FORC6_RS13455	COG0772	Belongs to the SEDS family
FORC6_RS13460	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FORC6_RS13465	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FORC6_RS13470	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FORC6_RS13475	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FORC6_RS13480	COG0768	penicillin binding
FORC6_RS13485	COG3116	cell division
FORC6_RS13490	COG0275	rRNA processing
FORC6_RS13500	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FORC6_RS13510	COG0792	nuclease activity
FORC6_RS13515	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FORC6_RS13520	COG2823	Periplasmic or secreted lipoprotein
FORC6_RS13525	COG2969	positive regulation of protein catabolic process
FORC6_RS13530	COG0625	glutathione transferase activity
FORC6_RS13535	COG2857	Cytochrome c1
FORC6_RS13540	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FORC6_RS13545	COG0723	plastoquinol--plastocyanin reductase activity
FORC6_RS13550	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FORC6_RS13555	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FORC6_RS13560	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FORC6_RS13565	COG3105	Protein conserved in bacteria
FORC6_RS13575	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FORC6_RS13580	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FORC6_RS13590	COG3150	esterase
FORC6_RS13600	COG3151	Protein conserved in bacteria
FORC6_RS13605	COG0494	nUDIX hydrolase
FORC6_RS13610	COG1538	Outer membrane efflux protein
FORC6_RS13615	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FORC6_RS13615	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FORC6_RS13620	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FORC6_RS13635	COG3025	triphosphatase activity
FORC6_RS13640	COG1392	Phosphate transport regulator
FORC6_RS13645	COG0306	phosphate transporter
FORC6_RS13650	COG4991	sh3 domain protein
FORC6_RS13660	COG3267	Type II secretory pathway component ExeA
FORC6_RS13660	COG3409	Peptidoglycan-binding domain 1 protein
FORC6_RS13665	COG0617	tRNA 3'-terminal CCA addition
FORC6_RS13670	COG1968	undecaprenyl-diphosphatase activity
FORC6_RS13675	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FORC6_RS13680	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FORC6_RS13685	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FORC6_RS13690	COG0596	Alpha beta hydrolase
FORC6_RS13695	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FORC6_RS13700	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FORC6_RS13705	COG1610	YqeY-like protein
FORC6_RS13710	COG0358	DNA primase activity
FORC6_RS13740	COG1715	Restriction endonuclease
FORC6_RS13815	COG1464	Belongs to the NlpA lipoprotein family
FORC6_RS13845	COG2213	PTS system mannitol-specific
FORC6_RS13845	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC6_RS13850	COG0246	Mannitol dehydrogenase
FORC6_RS13855	COG3722	fumarate hydratase activity
FORC6_RS13860	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FORC6_RS13865	COG5002	protein histidine kinase activity
FORC6_RS13880	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FORC6_RS13885	COG1349	DNA-binding transcription factor activity
FORC6_RS13890	COG0469	pyruvate kinase activity
FORC6_RS13905	COG0440	acetolactate synthase activity
FORC6_RS13910	COG0028	Belongs to the TPP enzyme family
FORC6_RS13915	COG1022	Amp-dependent synthetase and ligase
FORC6_RS13920	COG0583	DNA-binding transcription factor activity
FORC6_RS13940	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FORC6_RS13945	COG0473	3-isopropylmalate dehydrogenase activity
FORC6_RS13950	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FORC6_RS13955	COG0066	3-isopropylmalate dehydratase activity
FORC6_RS13965	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FORC6_RS13970	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FORC6_RS13975	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FORC6_RS13980	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FORC6_RS13985	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FORC6_RS13990	COG2967	ApaG domain
FORC6_RS13995	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FORC6_RS14010	COG2966	Psort location CytoplasmicMembrane, score
FORC6_RS14015	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FORC6_RS14025	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FORC6_RS14030	COG0142	geranyltranstransferase activity
FORC6_RS14040	COG0039	L-malate dehydrogenase activity
FORC6_RS14050	COG2358	TRAP transporter, solute receptor (TAXI family
FORC6_RS14065	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FORC6_RS14070	COG1178	ABC-type Fe3 transport system permease component
FORC6_RS14075	COG4143	(ABC) transporter
FORC6_RS14080	COG0163	prenyltransferase activity
FORC6_RS14085	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FORC6_RS14090	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
FORC6_RS14095	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FORC6_RS14105	COG2105	PFAM AIG2 family protein
FORC6_RS14115	COG0729	surface antigen
FORC6_RS14120	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FORC6_RS14130	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
FORC6_RS14145	COG4181	ATPase activity
FORC6_RS14165	COG0529	Catalyzes the synthesis of activated sulfate
FORC6_RS14170	COG0471	metal ion transport
FORC6_RS14170	COG3273	potassium ion transport
FORC6_RS14175	COG2895	sulfate adenylyltransferase (ATP) activity
FORC6_RS14180	COG0175	sulfate reduction
FORC6_RS14185	COG1648	precorrin-2 dehydrogenase activity
FORC6_RS14185	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FORC6_RS14190	COG0737	Belongs to the 5'-nucleotidase family
FORC6_RS14200	COG0513	Belongs to the DEAD box helicase family
FORC6_RS14205	COG2153	protein acetylation
FORC6_RS14215	COG0545	Peptidyl-prolyl cis-trans isomerase
FORC6_RS14225	COG0203	ribosomal protein L17
FORC6_RS14230	COG0202	RNA polymerase activity
FORC6_RS14240	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FORC6_RS14245	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FORC6_RS14250	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FORC6_RS14255	COG0201	protein transport
FORC6_RS14260	COG0200	Binds to the 23S rRNA
FORC6_RS14265	COG1841	ribosomal large subunit assembly
FORC6_RS14280	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FORC6_RS14285	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FORC6_RS14290	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FORC6_RS14295	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FORC6_RS14300	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FORC6_RS14305	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FORC6_RS14310	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FORC6_RS14315	COG0255	Belongs to the universal ribosomal protein uL29 family
FORC6_RS14325	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FORC6_RS14330	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FORC6_RS14335	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FORC6_RS14340	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FORC6_RS14350	COG0088	Forms part of the polypeptide exit tunnel
FORC6_RS14355	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FORC6_RS14365	COG0254	rRNA binding
FORC6_RS14370	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FORC6_RS14375	COG1609	Transcriptional regulator
FORC6_RS14385	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FORC6_RS14390	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FORC6_RS14395	COG1575	Belongs to the MenA family. Type 1 subfamily
FORC6_RS14400	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FORC6_RS14405	COG3074	FtsZ-dependent cytokinesis
FORC6_RS14410	COG1494	fructose-1,6-bisphosphatase
FORC6_RS14435	COG0149	triose-phosphate isomerase activity
FORC6_RS14460	COG0438	transferase activity, transferring glycosyl groups
FORC6_RS14460	COG1216	Glycosyl transferase, family 2
FORC6_RS14470	COG0471	metal ion transport
FORC6_RS14470	COG3273	potassium ion transport
FORC6_RS14500	COG0438	transferase activity, transferring glycosyl groups
FORC6_RS14500	COG1216	Glycosyl transferase, family 2
FORC6_RS14505	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FORC6_RS14505	COG0517	IMP dehydrogenase activity
FORC6_RS14510	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FORC6_RS14515	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FORC6_RS14540	COG1088	dTDP-glucose 4,6-dehydratase activity
FORC6_RS14600	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FORC6_RS14630	COG3156	type II secretion system protein K
FORC6_RS14650	COG1459	type II secretion system
FORC6_RS14655	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FORC6_RS14670	COG0175	sulfate reduction
FORC6_RS14675	COG0529	Catalyzes the synthesis of activated sulfate
FORC6_RS14685	COG2895	sulfate adenylyltransferase (ATP) activity
FORC6_RS14690	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FORC6_RS14715	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FORC6_RS14725	COG1560	Kdo2-lipid A biosynthetic process
FORC6_RS14730	COG0859	PFAM glycosyl transferase family 9
FORC6_RS14735	COG1519	Transferase
FORC6_RS14745	COG1083	cytidylyl-transferase
FORC6_RS14750	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FORC6_RS14760	COG2089	acid synthase
FORC6_RS14765	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FORC6_RS14770	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FORC6_RS14775	COG1086	Polysaccharide biosynthesis protein
FORC6_RS14780	COG1045	serine acetyltransferase
FORC6_RS14800	COG3642	lipopolysaccharide core region biosynthetic process
FORC6_RS14805	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FORC6_RS14810	COG0859	PFAM glycosyl transferase family 9
FORC6_RS14815	COG0463	Glycosyl transferase, family 2
FORC6_RS14825	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FORC6_RS14835	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FORC6_RS14850	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FORC6_RS14855	COG2003	Belongs to the UPF0758 family
FORC6_RS14865	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FORC6_RS14870	COG1309	transcriptional regulator
FORC6_RS14875	COG1560	Kdo2-lipid A biosynthetic process
FORC6_RS14880	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FORC6_RS14885	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FORC6_RS14890	COG1561	YicC-like family, N-terminal region
FORC6_RS14900	COG4608	Belongs to the ABC transporter superfamily
FORC6_RS14905	COG0444	Belongs to the ABC transporter superfamily
FORC6_RS14910	COG0747	negative chemotaxis
FORC6_RS14915	COG4239	(ABC) transporter, permease
FORC6_RS14920	COG4174	ABC transporter (Permease)
FORC6_RS14940	COG0811	peptide transport
FORC6_RS14945	COG0848	biopolymer transport protein
FORC6_RS14960	COG0194	GDP metabolic process
FORC6_RS14965	COG1758	RNA polymerase activity
FORC6_RS14970	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FORC6_RS14975	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FORC6_RS14980	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FORC6_RS14990	COG2233	PERMEase
FORC6_RS15010	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FORC6_RS15020	COG2183	response to ionizing radiation
FORC6_RS15030	COG0596	Alpha beta hydrolase
FORC6_RS15035	COG1040	competence protein
FORC6_RS15040	COG0316	Belongs to the HesB IscA family
FORC6_RS15040	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FORC6_RS15045	COG0494	nUDIX hydrolase
FORC6_RS15050	COG1218	3'(2'),5'-bisphosphate nucleotidase
FORC6_RS15060	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
FORC6_RS15065	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
FORC6_RS15070	COG3156	type II secretion system protein K
FORC6_RS15075	COG4795	General secretion pathway protein
FORC6_RS15080	COG2165	general secretion pathway protein
FORC6_RS15085	COG2165	general secretion pathway protein
FORC6_RS15090	COG2165	general secretion pathway protein
FORC6_RS15095	COG1459	type II secretion system
FORC6_RS15100	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FORC6_RS15110	COG3031	protein transport across the cell outer membrane
FORC6_RS15115	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FORC6_RS15120	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FORC6_RS15125	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FORC6_RS15135	COG0456	acetyltransferase
FORC6_RS15140	COG1490	D-aminoacyl-tRNA deacylase activity
FORC6_RS15145	COG1295	ribonuclease BN
FORC6_RS15160	COG1217	gtp-binding protein TYPA
FORC6_RS15165	COG0174	glutamine synthetase
FORC6_RS15175	COG3852	Histidine kinase
FORC6_RS15180	COG2204	response regulator
FORC6_RS15190	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FORC6_RS15225	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FORC6_RS15230	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FORC6_RS15230	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FORC6_RS15245	COG0084	hydrolase, TatD family'
FORC6_RS15250	COG0805	protein transport
FORC6_RS15255	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FORC6_RS15260	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FORC6_RS15265	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FORC6_RS15270	COG3165	ubiquinone biosynthetic process from chorismate
FORC6_RS15275	COG2226	methyltransferase
FORC6_RS15280	COG1322	Protein conserved in bacteria
FORC6_RS15295	COG0628	permease
FORC6_RS15340	COG2823	Periplasmic or secreted lipoprotein
FORC6_RS15350	COG2081	HI0933 family
FORC6_RS15360	COG1528	Iron-storage protein
FORC6_RS15365	COG0589	response to stress
FORC6_RS15380	COG0742	ribosomal rna small subunit methyltransferase
FORC6_RS15385	COG5001	Diguanylate cyclase
FORC6_RS15385	COG5002	protein histidine kinase activity
FORC6_RS15390	COG1522	sequence-specific DNA binding
FORC6_RS15395	COG0339	signal peptide processing
FORC6_RS15400	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FORC6_RS15405	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FORC6_RS15410	COG0583	DNA-binding transcription factor activity
FORC6_RS15415	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FORC6_RS15420	COG0800	Aldolase
FORC6_RS15425	COG2610	gluconate transmembrane transporter activity
FORC6_RS15430	COG3265	gluconokinase activity
FORC6_RS15435	COG0129	dihydroxy-acid dehydratase activity
FORC6_RS15450	COG0583	DNA-binding transcription factor activity
FORC6_RS15455	COG1609	Transcriptional regulator
FORC6_RS15490	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FORC6_RS15495	COG0601	transmembrane transport
FORC6_RS15500	COG0747	negative chemotaxis
FORC6_RS15505	COG4172	Belongs to the ABC transporter superfamily
FORC6_RS15560	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FORC6_RS15565	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FORC6_RS15570	COG2960	long-chain fatty acid transporting porin activity
FORC6_RS15575	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FORC6_RS15580	COG0583	DNA-binding transcription factor activity
FORC6_RS15615	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FORC6_RS15625	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FORC6_RS15630	COG0408	coproporphyrinogen oxidase activity
FORC6_RS15635	COG0009	L-threonylcarbamoyladenylate synthase
FORC6_RS15640	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FORC6_RS15645	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FORC6_RS15650	COG0551	DNA topoisomerase type I activity
FORC6_RS15655	COG2922	Belongs to the Smg family
FORC6_RS15660	COG0758	DNA mediated transformation
FORC6_RS15670	COG0242	peptide deformylase activity
FORC6_RS15675	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FORC6_RS15680	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FORC6_RS15680	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FORC6_RS15685	COG0569	domain protein
FORC6_RS15690	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FORC6_RS15700	COG1272	protein, Hemolysin III
FORC6_RS15705	COG4326	sporulation control protein
FORC6_RS15710	COG3084	Protein conserved in bacteria
FORC6_RS15720	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FORC6_RS15725	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FORC6_RS15730	COG0204	Acyl-transferase
FORC6_RS15740	COG0606	chelatase, subunit chli
FORC6_RS15750	COG3978	acetolactate synthase activity
FORC6_RS15755	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FORC6_RS15760	COG0129	dihydroxy-acid dehydratase activity
FORC6_RS15770	COG0583	DNA-binding transcription factor activity
FORC6_RS15775	COG2814	Major facilitator Superfamily
FORC6_RS15780	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC6_RS15785	COG0765	amino acid transport
FORC6_RS15790	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FORC6_RS15795	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FORC6_RS15800	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FORC6_RS15805	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FORC6_RS15810	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FORC6_RS15815	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FORC6_RS15830	COG0356	it plays a direct role in the translocation of protons across the membrane
FORC6_RS15835	COG3312	ion transport
FORC6_RS15840	COG1475	DNA binding
FORC6_RS15845	COG1192	Involved in chromosome partitioning
FORC6_RS15850	COG0357	Ribosomal RNA small subunit methyltransferase G
FORC6_RS15855	COG0445	tRNA wobble uridine modification
FORC6_RS15860	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FORC6_RS15865	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FORC6_RS15870	COG0706	membrane insertase activity
FORC6_RS15875	COG0594	ribonuclease P activity
FORC6_RS15885	COG1126	abc transporter atp-binding protein
FORC6_RS15915	COG4608	Belongs to the ABC transporter superfamily
FORC6_RS15920	COG0444	Belongs to the ABC transporter superfamily
FORC6_RS15955	COG0217	transcriptional regulatory protein
FORC6_RS15960	COG0772	Belongs to the SEDS family
FORC6_RS15990	COG3275	phosphorelay sensor kinase activity
FORC6_RS15995	COG3279	Response regulator of the LytR AlgR family
FORC6_RS16005	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FORC6_RS16030	COG0786	glutamate:sodium symporter activity
FORC6_RS16040	COG1131	(ABC) transporter
FORC6_RS16045	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FORC6_RS16050	COG0786	glutamate:sodium symporter activity
FORC6_RS16060	COG0363	glucosamine-6-phosphate deaminase activity
FORC6_RS16080	COG1741	Belongs to the pirin family
FORC6_RS16085	COG2259	Doxx family
FORC6_RS16095	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FORC6_RS16100	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FORC6_RS16110	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FORC6_RS16150	COG3123	guanosine phosphorylase activity
FORC6_RS16160	COG5001	Diguanylate cyclase
FORC6_RS16165	COG0534	Mate efflux family protein
FORC6_RS16170	COG0564	pseudouridine synthase activity
FORC6_RS16185	COG0583	DNA-binding transcription factor activity
FORC6_RS16190	COG0561	phosphatase activity
FORC6_RS16200	COG2199	diguanylate cyclase activity
FORC6_RS16215	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FORC6_RS16220	COG2162	N-hydroxyarylamine O-acetyltransferase activity
FORC6_RS16225	COG0583	DNA-binding transcription factor activity
FORC6_RS16240	COG1414	Transcriptional regulator
FORC6_RS16245	COG1028	Short-chain dehydrogenase reductase Sdr
FORC6_RS16255	COG1917	Cupin 2, conserved barrel domain protein
FORC6_RS16270	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FORC6_RS16275	COG0800	Aldolase
FORC6_RS16295	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FORC6_RS16300	COG0823	Involved in the tonB-independent uptake of proteins
FORC6_RS16305	COG2375	cellular response to nickel ion
FORC6_RS16335	COG1357	PFAM Pentapeptide repeats (8 copies)
FORC6_RS16340	COG3047	cAMP biosynthetic process
FORC6_RS16370	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
FORC6_RS16370	COG3408	Glycogen debranching enzyme
FORC6_RS16375	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
FORC6_RS16385	COG0583	DNA-binding transcription factor activity
FORC6_RS16395	COG0583	DNA-binding transcription factor activity
FORC6_RS16410	COG0546	phosphoglycolate phosphatase activity
FORC6_RS16430	COG3835	regulator
FORC6_RS16435	COG2610	gluconate transmembrane transporter activity
FORC6_RS16440	COG1929	Belongs to the glycerate kinase type-1 family
FORC6_RS16445	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FORC6_RS16465	COG0456	acetyltransferase
FORC6_RS16480	COG1028	Short-chain dehydrogenase reductase Sdr
FORC6_RS16490	COG3005	denitrification pathway
FORC6_RS16495	COG0243	molybdopterin cofactor binding
FORC6_RS16505	COG0352	thiamine-phosphate diphosphorylase activity
FORC6_RS16510	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
FORC6_RS16515	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FORC6_RS16520	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FORC6_RS16525	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FORC6_RS16530	COG1116	anion transmembrane transporter activity
FORC6_RS16535	COG0351	phosphomethylpyrimidine kinase
FORC6_RS16540	COG0312	modulator of DNA gyrase
FORC6_RS16545	COG0312	modulator of DNA gyrase
FORC6_RS16550	COG1901	pseudouridine methyltransferase
FORC6_RS16605	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FORC6_RS16615	COG0584	glycerophosphoryl diester phosphodiesterase
FORC6_RS16620	COG0039	L-malate dehydrogenase activity
FORC6_RS16625	COG0745	RESPONSE REGULATOR receiver
FORC6_RS16645	COG0811	peptide transport
FORC6_RS16650	COG0811	peptide transport
FORC6_RS16655	COG0848	biopolymer transport protein
FORC6_RS16700	COG0803	Belongs to the bacterial solute-binding protein 9 family
FORC6_RS16705	COG1121	(ABC) transporter
FORC6_RS16710	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FORC6_RS16725	COG1770	oligopeptidase
FORC6_RS16730	COG2814	Major facilitator Superfamily
FORC6_RS16735	COG0010	Belongs to the arginase family
FORC6_RS16740	COG1166	arginine decarboxylase activity
FORC6_RS16750	COG0189	ligase activity
FORC6_RS16750	COG4067	protein conserved in archaea
FORC6_RS16755	COG0189	ligase activity
FORC6_RS16765	COG0583	DNA-binding transcription factor activity
FORC6_RS16810	COG2199	diguanylate cyclase activity
FORC6_RS16830	COG0579	oxidoreductase
FORC6_RS16840	COG3033	Beta-eliminating lyase
FORC6_RS16855	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FORC6_RS16870	COG3706	GGDEF domain
FORC6_RS16875	COG0840	transmembrane signaling receptor activity
FORC6_RS16890	COG3706	GGDEF domain
FORC6_RS16895	COG0415	Belongs to the DNA photolyase family
FORC6_RS16900	COG3046	protein related to deoxyribodipyrimidine photolyase
FORC6_RS16910	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FORC6_RS16910	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FORC6_RS16915	COG1765	OsmC-like protein
FORC6_RS16920	COG0110	maltose O-acetyltransferase activity
FORC6_RS16960	COG1011	Hydrolase
FORC6_RS16975	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
FORC6_RS16985	COG2067	long-chain fatty acid transport protein
FORC6_RS16990	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FORC6_RS16995	COG1136	(ABC) transporter
FORC6_RS16995	COG0577	efflux transmembrane transporter activity
FORC6_RS17005	COG3240	lipase activity
FORC6_RS17035	COG1609	Transcriptional regulator
FORC6_RS17040	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FORC6_RS17045	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FORC6_RS17050	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FORC6_RS17055	COG1840	ABC-type Fe3 transport system, periplasmic component
FORC6_RS17065	COG3842	ATPase activity
FORC6_RS17090	COG2990	Protein conserved in bacteria
FORC6_RS17095	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FORC6_RS17100	COG2866	Carboxypeptidase
FORC6_RS17110	COG0583	DNA-binding transcription factor activity
FORC6_RS17130	COG3104	oligopeptide transport
FORC6_RS17135	COG1760	l-serine dehydratase
FORC6_RS17155	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FORC6_RS17160	COG0741	lytic transglycosylase activity
FORC6_RS17180	COG1815	bacterial-type flagellum-dependent cell motility
FORC6_RS17185	COG1558	bacterial-type flagellum-dependent cell motility
FORC6_RS17190	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FORC6_RS17195	COG1749	Flagellar hook protein flgE
FORC6_RS17200	COG4787	bacterial-type flagellum-dependent cell motility
FORC6_RS17205	COG4786	Flagellar basal body rod
FORC6_RS17210	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FORC6_RS17215	COG1706	bacterial-type flagellum-dependent cell motility
FORC6_RS17225	COG4786	Flagellar basal body rod
FORC6_RS17225	COG1256	bacterial-type flagellum assembly
FORC6_RS17250	COG1304	FMN binding
FORC6_RS17265	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FORC6_RS17270	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FORC6_RS17275	COG0459	protein refolding
FORC6_RS17285	COG1280	lysine exporter protein (LysE YggA)
FORC6_RS17305	COG1309	transcriptional regulator
FORC6_RS17315	COG0737	Belongs to the 5'-nucleotidase family
FORC6_RS17320	COG2070	2-Nitropropane dioxygenase
FORC6_RS17325	COG3537	Alpha-1,2-mannosidase
FORC6_RS17330	COG3537	Alpha-1,2-mannosidase
FORC6_RS17340	COG3537	Alpha-1,2-mannosidase
FORC6_RS17345	COG3537	Alpha-1,2-mannosidase
FORC6_RS17350	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FORC6_RS17370	COG0346	lactoylglutathione lyase activity
FORC6_RS17375	COG1349	DNA-binding transcription factor activity
FORC6_RS17385	COG0753	catalase activity
FORC6_RS17395	COG1335	isochorismatase
FORC6_RS17405	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FORC6_RS17430	COG0583	DNA-binding transcription factor activity
FORC6_RS17445	COG3713	MltA-interacting MipA family protein
FORC6_RS17450	COG3015	lipoprotein NlpE involved in copper resistance
FORC6_RS17455	COG1342	Belongs to the UPF0251 family
FORC6_RS17485	COG4948	Mandelate Racemase Muconate Lactonizing
FORC6_RS17495	COG0583	DNA-binding transcription factor activity
FORC6_RS17530	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FORC6_RS17580	COG3842	ATPase activity
FORC6_RS17610	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FORC6_RS17620	COG2197	response regulator
FORC6_RS17630	COG3706	GGDEF domain
FORC6_RS17650	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FORC6_RS17670	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FORC6_RS17685	COG0574	Belongs to the PEP-utilizing enzyme family
FORC6_RS17685	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FORC6_RS17690	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FORC6_RS17695	COG0252	asparaginase activity
FORC6_RS17700	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FORC6_RS17705	COG0583	DNA-binding transcription factor activity
FORC6_RS17720	COG3122	Protein conserved in bacteria
FORC6_RS17730	COG1028	Short-chain dehydrogenase reductase Sdr
FORC6_RS17740	COG1063	alcohol dehydrogenase
FORC6_RS17745	COG1902	pentaerythritol trinitrate reductase activity
FORC6_RS17760	COG0583	DNA-binding transcription factor activity
FORC6_RS17770	COG0513	Belongs to the DEAD box helicase family
FORC6_RS17795	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FORC6_RS17800	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FORC6_RS17800	COG2207	Transcriptional regulator
FORC6_RS17820	COG3746	phosphate-selective porin O and P
FORC6_RS17835	COG1028	Short-chain dehydrogenase reductase Sdr
FORC6_RS17870	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FORC6_RS17880	COG0625	glutathione transferase activity
FORC6_RS17885	COG1686	Belongs to the peptidase S11 family
FORC6_RS17900	COG0678	peroxiredoxin activity
FORC6_RS17900	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FORC6_RS17905	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FORC6_RS17915	COG1278	Cold shock
FORC6_RS17920	COG1741	Belongs to the pirin family
FORC6_RS17925	COG4667	esterase of the alpha-beta hydrolase superfamily
FORC6_RS17955	COG0673	inositol 2-dehydrogenase activity
FORC6_RS17960	COG2194	sulfuric ester hydrolase activity
FORC6_RS17965	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FORC6_RS17975	COG2205	protein histidine kinase activity
FORC6_RS17980	COG0745	RESPONSE REGULATOR receiver
FORC6_RS17985	COG4221	oxidoreductase activity
FORC6_RS18000	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FORC6_RS18020	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FORC6_RS18030	COG2814	Major facilitator Superfamily
FORC6_RS18040	COG1418	mRNA catabolic process
FORC6_RS18050	COG0402	S-adenosylhomocysteine deaminase activity
FORC6_RS18055	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FORC6_RS18065	COG2239	Acts as a magnesium transporter
FORC6_RS18070	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FORC6_RS18085	COG0531	amino acid
FORC6_RS18090	COG1522	sequence-specific DNA binding
FORC6_RS18115	COG0784	Response regulator, receiver
FORC6_RS18115	COG5002	protein histidine kinase activity
FORC6_RS18115	COG2205	protein histidine kinase activity
FORC6_RS18120	COG0673	inositol 2-dehydrogenase activity
FORC6_RS18125	COG0534	Mate efflux family protein
FORC6_RS18130	COG2926	Belongs to the UPF0265 family
FORC6_RS18140	COG3132	Protein of unknown function, DUF480
FORC6_RS18145	COG2827	Endonuclease containing a URI domain
FORC6_RS18150	COG1879	ABC-type sugar transport system periplasmic component
FORC6_RS18155	COG0784	Response regulator, receiver
FORC6_RS18155	COG2205	protein histidine kinase activity
FORC6_RS18165	COG1566	PFAM secretion protein HlyD family protein
FORC6_RS18185	COG1522	sequence-specific DNA binding
FORC6_RS18210	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FORC6_RS18215	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FORC6_RS18235	COG0183	Belongs to the thiolase family
FORC6_RS18250	COG3005	denitrification pathway
FORC6_RS18270	COG3850	Histidine kinase
FORC6_RS18275	COG2197	response regulator
FORC6_RS18290	COG2195	Cleaves the N-terminal amino acid of tripeptides
FORC6_RS18310	COG0840	transmembrane signaling receptor activity
FORC6_RS18320	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FORC6_RS18330	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FORC6_RS18335	COG2814	Major facilitator Superfamily
FORC6_RS18340	COG0840	transmembrane signaling receptor activity
FORC6_RS18345	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FORC6_RS18350	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FORC6_RS18375	COG2897	thiosulfate sulfurtransferase activity
FORC6_RS18395	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FORC6_RS18405	COG0302	gtp cyclohydrolase
FORC6_RS18410	COG1914	H( )-stimulated, divalent metal cation uptake system
FORC6_RS18420	COG0038	chloride channel
FORC6_RS18435	COG4989	oxidoreductase activity
FORC6_RS18450	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FORC6_RS18450	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FORC6_RS18455	COG0516	GMP reductase activity
FORC6_RS18460	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FORC6_RS18525	COG3474	cytochrome
FORC6_RS18535	COG0789	Transcriptional regulator
FORC6_RS18540	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FORC6_RS18545	COG0384	phenazine biosynthesis protein PhzF
FORC6_RS18550	COG1294	oxidase, subunit
FORC6_RS18555	COG1271	oxidase subunit
FORC6_RS18560	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FORC6_RS18565	COG0110	maltose O-acetyltransferase activity
FORC6_RS18585	COG3850	Histidine kinase
FORC6_RS18585	COG3437	response regulator, receiver
FORC6_RS18585	COG2205	protein histidine kinase activity
FORC6_RS18585	COG4999	Histidine kinase
FORC6_RS18595	COG4770	biotin carboxylase activity
FORC6_RS18605	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FORC6_RS18610	COG1960	acyl-CoA dehydrogenase activity
FORC6_RS18620	COG0183	Belongs to the thiolase family
FORC6_RS18630	COG1960	acyl-CoA dehydrogenase activity
FORC6_RS18635	COG1024	Enoyl-CoA hydratase
FORC6_RS18655	COG3706	GGDEF domain
FORC6_RS18660	COG1309	transcriptional regulator
FORC6_RS18665	COG1012	belongs to the aldehyde dehydrogenase family
FORC6_RS18680	COG4176	ABC-type proline glycine betaine transport system permease component
FORC6_RS18685	COG0517	IMP dehydrogenase activity
FORC6_RS18685	COG4175	Glycine betaine
FORC6_RS18700	COG0330	HflC and HflK could
FORC6_RS18710	COG5001	Diguanylate cyclase
FORC6_RS18710	COG3300	MHYT domain
FORC6_RS18720	COG2205	protein histidine kinase activity
FORC6_RS18720	COG0784	Response regulator, receiver
FORC6_RS18775	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FORC6_RS18780	COG5001	Diguanylate cyclase
FORC6_RS18785	COG1869	D-ribose catabolic process
FORC6_RS18790	COG1129	ABC transporter
FORC6_RS18795	COG1172	Belongs to the binding-protein-dependent transport system permease family
FORC6_RS18800	COG1879	ABC-type sugar transport system periplasmic component
FORC6_RS18805	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FORC6_RS18810	COG1609	Transcriptional regulator
FORC6_RS18825	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
FORC6_RS18835	COG4607	ABC-type enterochelin transport system periplasmic component
FORC6_RS18840	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC6_RS18845	COG4605	iron ion homeostasis
FORC6_RS18850	COG4604	ABC transporter, ATP-binding protein
FORC6_RS18855	COG0789	Transcriptional regulator
FORC6_RS18860	COG2207	Transcriptional regulator
FORC6_RS18865	COG4771	TonB-dependent receptor
FORC6_RS18865	COG1629	transport
FORC6_RS18895	COG1289	transmembrane transporter activity
FORC6_RS18900	COG0210	DNA helicase
FORC6_RS18905	COG1803	Methylglyoxal synthase
FORC6_RS18910	COG1879	ABC-type sugar transport system periplasmic component
FORC6_RS18915	COG0784	Response regulator, receiver
FORC6_RS18915	COG2198	Histidine kinase
FORC6_RS18915	COG2205	protein histidine kinase activity
FORC6_RS18930	COG0745	RESPONSE REGULATOR receiver
FORC6_RS18935	COG3119	arylsulfatase activity
FORC6_RS18940	COG3119	arylsulfatase activity
FORC6_RS18955	COG3119	arylsulfatase activity
FORC6_RS18960	COG0641	radical SAM
FORC6_RS18965	COG0714	Associated with various cellular activities
FORC6_RS18995	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FORC6_RS19000	COG0583	DNA-binding transcription factor activity
FORC6_RS19005	COG1597	lipid kinase activity
FORC6_RS19010	COG3111	PFAM Bacterial OB fold (BOF) protein
FORC6_RS19025	COG0641	radical SAM
FORC6_RS19050	COG0501	Belongs to the peptidase M48B family
FORC6_RS19055	COG1704	LemA family
FORC6_RS19060	COG3069	C4-dicarboxylate transmembrane transporter activity
FORC6_RS19070	COG0456	acetyltransferase
FORC6_RS19070	COG1214	PFAM Peptidase M22, glycoprotease
FORC6_RS19120	COG0471	metal ion transport
FORC6_RS19125	COG3290	protein histidine kinase activity
FORC6_RS19130	COG4565	transcriptional regulatory protein
FORC6_RS19145	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FORC6_RS19150	COG5642	Protein of unknown function (DUF2384)
FORC6_RS19170	COG1902	pentaerythritol trinitrate reductase activity
FORC6_RS19175	COG0346	lactoylglutathione lyase activity
FORC6_RS19200	COG2239	Acts as a magnesium transporter
FORC6_RS19230	COG0242	peptide deformylase activity
FORC6_RS19270	COG2176	DNA-directed DNA polymerase activity
FORC6_RS19275	COG0583	DNA-binding transcription factor activity
FORC6_RS19280	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FORC6_RS19285	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
FORC6_RS19325	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FORC6_RS19325	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FORC6_RS19330	COG0509	glycine decarboxylation via glycine cleavage system
FORC6_RS19335	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FORC6_RS19375	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
FORC6_RS19375	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FORC6_RS19375	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FORC6_RS19380	COG1105	Belongs to the carbohydrate kinase PfkB family
FORC6_RS19385	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC6_RS19385	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC6_RS19390	COG1609	Transcriptional regulator
FORC6_RS19405	COG2199	diguanylate cyclase activity
FORC6_RS19405	COG2200	EAL domain
FORC6_RS19405	COG2203	Gaf domain
FORC6_RS19410	COG0765	amino acid transport
FORC6_RS19415	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC6_RS19420	COG0765	amino acid transport
FORC6_RS19425	COG1126	abc transporter atp-binding protein
FORC6_RS19430	COG0469	pyruvate kinase activity
FORC6_RS19435	COG2271	Major facilitator Superfamily
FORC6_RS19460	COG1979	alcohol dehydrogenase
FORC6_RS19465	COG2207	Transcriptional regulator
FORC6_RS19475	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FORC6_RS19480	COG2759	Belongs to the formate--tetrahydrofolate ligase family
FORC6_RS19485	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FORC6_RS19500	COG3437	response regulator, receiver
FORC6_RS19500	COG0784	Response regulator, receiver
FORC6_RS19505	COG0546	phosphoglycolate phosphatase activity
FORC6_RS19510	COG0840	transmembrane signaling receptor activity
FORC6_RS19515	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
FORC6_RS19520	COG0513	Belongs to the DEAD box helicase family
FORC6_RS19525	COG4943	cyclic-guanylate-specific phosphodiesterase activity
FORC6_RS19540	COG3038	cytochrome b561
FORC6_RS19545	COG2353	YceI-like domain
FORC6_RS19550	COG2116	formate transmembrane transporter activity
FORC6_RS19565	COG3593	DNA synthesis involved in DNA repair
FORC6_RS19570	COG0737	Belongs to the 5'-nucleotidase family
FORC6_RS19575	COG0861	Integral membrane protein TerC family
FORC6_RS19590	COG2267	carboxylic ester hydrolase activity
FORC6_RS19595	COG2067	long-chain fatty acid transport protein
FORC6_RS19610	COG2050	protein possibly involved in aromatic compounds catabolism
FORC6_RS19645	COG0484	heat shock protein binding
FORC6_RS19655	COG3300	MHYT domain
FORC6_RS19655	COG5001	Diguanylate cyclase
FORC6_RS19660	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FORC6_RS19670	COG4181	ATPase activity
FORC6_RS19675	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FORC6_RS19685	COG1984	allophanate hydrolase subunit 2
FORC6_RS19690	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FORC6_RS19695	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FORC6_RS19700	COG3447	MASE1 domain protein
FORC6_RS19700	COG5001	Diguanylate cyclase
FORC6_RS19700	COG5002	protein histidine kinase activity
FORC6_RS19705	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FORC6_RS19710	COG1629	transport
FORC6_RS19710	COG4771	TonB-dependent receptor
FORC6_RS19715	COG0583	DNA-binding transcription factor activity
FORC6_RS19720	COG1042	CoA-binding domain protein
FORC6_RS19720	COG0045	succinate-CoA ligase (ADP-forming) activity
FORC6_RS19720	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC6_RS19730	COG1181	Belongs to the D-alanine--D-alanine ligase family
FORC6_RS19740	COG0023	Translation Initiation Factor
FORC6_RS19790	COG4128	Pfam Zonular occludens toxin
FORC6_RS19810	COG0583	DNA-binding transcription factor activity
FORC6_RS19820	COG0589	response to stress
FORC6_RS19845	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FORC6_RS19850	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FORC6_RS19875	COG2203	Gaf domain
FORC6_RS19875	COG4251	negative regulation of phosphorylation
FORC6_RS19875	COG3706	GGDEF domain
FORC6_RS19875	COG5001	Diguanylate cyclase
FORC6_RS19885	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FORC6_RS19890	COG4149	molybdate abc transporter
FORC6_RS19895	COG0725	ABC transporter, periplasmic molybdate-binding protein
FORC6_RS19900	COG1492	cobalamin metabolic process
FORC6_RS19905	COG3111	PFAM Bacterial OB fold (BOF) protein
FORC6_RS19915	COG4067	protein conserved in archaea
FORC6_RS19915	COG0189	ligase activity
FORC6_RS19930	COG0534	Mate efflux family protein
FORC6_RS19935	COG0602	queuosine metabolic process
FORC6_RS19940	COG1328	CTP reductase activity
FORC6_RS19955	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FORC6_RS19985	COG0243	molybdopterin cofactor binding
FORC6_RS19990	COG0583	DNA-binding transcription factor activity
FORC6_RS19995	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FORC6_RS20005	COG2197	response regulator
FORC6_RS20010	COG3851	Histidine kinase
FORC6_RS20015	COG2271	Major facilitator Superfamily
FORC6_RS20040	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FORC6_RS20045	COG3118	belongs to the thioredoxin family
FORC6_RS20055	COG3292	Two component regulator propeller
FORC6_RS20055	COG0745	RESPONSE REGULATOR receiver
FORC6_RS20055	COG2205	protein histidine kinase activity
FORC6_RS20060	COG0534	Mate efflux family protein
FORC6_RS20090	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FORC6_RS20110	COG2116	formate transmembrane transporter activity
FORC6_RS20120	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FORC6_RS20125	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FORC6_RS20165	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FORC6_RS20165	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FORC6_RS20205	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FORC6_RS20220	COG0277	FAD linked oxidase domain protein
FORC6_RS20225	COG0583	DNA-binding transcription factor activity
FORC6_RS20240	COG2425	protein containing a von Willebrand factor type A (vWA) domain
FORC6_RS20255	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
FORC6_RS20265	COG1288	antiporter activity
FORC6_RS20275	COG0671	phosphoesterase, PA-phosphatase related
FORC6_RS20285	COG2962	Rard protein
FORC6_RS20300	COG0835	chemotaxis
FORC6_RS20300	COG0784	Response regulator, receiver
FORC6_RS20315	COG2197	response regulator
FORC6_RS20325	COG3706	GGDEF domain
FORC6_RS20330	COG2197	response regulator
FORC6_RS20335	COG5001	Diguanylate cyclase
FORC6_RS20335	COG3300	MHYT domain
FORC6_RS20350	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FORC6_RS20360	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FORC6_RS20385	COG2814	Major facilitator Superfamily
FORC6_RS20395	COG3040	lipid binding
FORC6_RS20415	COG0419	ATPase involved in DNA repair
FORC6_RS20420	COG0420	3'-5' exonuclease activity
FORC6_RS20490	COG0631	protein serine/threonine phosphatase activity
FORC6_RS20525	COG0515	serine threonine protein kinase
FORC6_RS20525	COG2815	serine threonine protein kinase
FORC6_RS20580	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FORC6_RS20580	COG2146	nitrite reductase [NAD(P)H] activity
FORC6_RS20585	COG1116	anion transmembrane transporter activity
FORC6_RS20590	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FORC6_RS20595	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FORC6_RS20600	COG3707	response regulator
FORC6_RS20615	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FORC6_RS20615	COG1648	precorrin-2 dehydrogenase activity
FORC6_RS20620	COG0243	molybdopterin cofactor binding
FORC6_RS20630	COG0814	amino acid
FORC6_RS20655	COG1785	Belongs to the alkaline phosphatase family
FORC6_RS20670	COG0745	RESPONSE REGULATOR receiver
FORC6_RS20695	COG2847	Copper chaperone PCu(A)C
FORC6_RS20700	COG0443	Heat shock 70 kDa protein
FORC6_RS20735	COG0625	glutathione transferase activity
FORC6_RS20750	COG4160	amino acid transport
FORC6_RS20755	COG4215	(ABC) transporter
FORC6_RS20760	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC6_RS20765	COG1126	abc transporter atp-binding protein
FORC6_RS20795	COG1902	pentaerythritol trinitrate reductase activity
FORC6_RS20810	COG0109	protoheme IX farnesyltransferase activity
FORC6_RS20815	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FORC6_RS20820	COG1845	cytochrome c oxidase, subunit III
FORC6_RS20825	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FORC6_RS20830	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FORC6_RS20835	COG1028	Short-chain dehydrogenase reductase Sdr
FORC6_RS20845	COG1024	Enoyl-CoA hydratase
FORC6_RS20850	COG1024	Enoyl-CoA hydratase
FORC6_RS20855	COG1960	acyl-CoA dehydrogenase activity
FORC6_RS20865	COG0183	Belongs to the thiolase family
FORC6_RS20875	COG1960	acyl-CoA dehydrogenase activity
FORC6_RS20880	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FORC6_RS20885	COG1024	Enoyl-CoA hydratase
FORC6_RS20895	COG5413	integral membrane protein
FORC6_RS20910	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FORC6_RS20915	COG5001	Diguanylate cyclase
FORC6_RS20920	COG0513	Belongs to the DEAD box helicase family
FORC6_RS20925	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
FORC6_RS20940	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FORC6_RS20960	COG0641	radical SAM
FORC6_RS20975	COG0840	transmembrane signaling receptor activity
FORC6_RS20980	COG1119	ATPase activity
FORC6_RS20985	COG2200	EAL domain
FORC6_RS21005	COG0513	Belongs to the DEAD box helicase family
FORC6_RS21010	COG0523	cobalamin synthesis protein
FORC6_RS21020	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
FORC6_RS21030	COG0133	tryptophan synthase activity
FORC6_RS21035	COG4628	conserved protein (DUF2132)
FORC6_RS21040	COG0513	Belongs to the DEAD box helicase family
FORC6_RS21045	COG3530	Putative quorum-sensing-regulated virulence factor
FORC6_RS21065	COG2154	pterin-4-alpha-carbinolamine dehydratase
FORC6_RS21070	COG3186	Phenylalanine-4-hydroxylase
FORC6_RS21075	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FORC6_RS21080	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FORC6_RS21115	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
FORC6_RS21120	COG1454	alcohol dehydrogenase
FORC6_RS21125	COG2133	pyrroloquinoline quinone binding
FORC6_RS21135	COG0783	Belongs to the Dps family
FORC6_RS21140	COG0840	transmembrane signaling receptor activity
FORC6_RS21150	COG1136	(ABC) transporter
FORC6_RS21150	COG0577	efflux transmembrane transporter activity
FORC6_RS21170	COG2199	diguanylate cyclase activity
FORC6_RS21185	COG1278	Cold shock
FORC6_RS21215	COG0545	Peptidyl-prolyl cis-trans isomerase
FORC6_RS21220	COG0109	protoheme IX farnesyltransferase activity
FORC6_RS21225	COG1612	heme a metabolic process
FORC6_RS21250	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
FORC6_RS21260	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FORC6_RS21265	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FORC6_RS21275	COG1280	lysine exporter protein (LysE YggA)
FORC6_RS21280	COG2207	Transcriptional regulator
FORC6_RS21310	COG0697	spore germination
FORC6_RS21325	COG2814	Major facilitator Superfamily
FORC6_RS21330	COG0583	DNA-binding transcription factor activity
FORC6_RS21335	COG5001	Diguanylate cyclase
FORC6_RS21340	COG0739	heme binding
FORC6_RS21360	COG3314	Sporulation integral membrane protein YlbJ
FORC6_RS21375	COG0814	amino acid
FORC6_RS21395	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FORC6_RS21400	COG1072	(Pantothenic acid kinase))
FORC6_RS21410	COG1063	alcohol dehydrogenase
FORC6_RS21415	COG2213	PTS system mannitol-specific
FORC6_RS21420	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC6_RS21435	COG0798	PFAM Bile acid sodium symporter
FORC6_RS21445	COG1881	PFAM PEBP family protein
FORC6_RS21455	COG2706	6-phosphogluconolactonase activity
FORC6_RS21460	COG0840	transmembrane signaling receptor activity
FORC6_RS21470	COG1131	(ABC) transporter
FORC6_RS21475	COG0842	Transport permease protein
FORC6_RS21490	COG3383	formate dehydrogenase (NAD+) activity
FORC6_RS21510	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FORC6_RS21535	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC6_RS21545	COG2067	long-chain fatty acid transport protein
FORC6_RS21555	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FORC6_RS21565	COG1505	serine-type exopeptidase activity
FORC6_RS21570	COG0488	(ABC) transporter
FORC6_RS21575	COG0589	response to stress
FORC6_RS21580	COG2249	NAD(P)H dehydrogenase (quinone) activity
FORC6_RS21600	COG0366	Alpha amylase catalytic
FORC6_RS21610	COG4934	collagen metabolic process
FORC6_RS21625	COG0641	radical SAM
FORC6_RS21645	COG0583	DNA-binding transcription factor activity
FORC6_RS21650	COG0783	Belongs to the Dps family
FORC6_RS21655	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FORC6_RS21690	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FORC6_RS21700	COG2814	Major facilitator Superfamily
FORC6_RS21715	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FORC6_RS21720	COG0835	chemotaxis
FORC6_RS21720	COG0784	Response regulator, receiver
FORC6_RS21730	COG0748	coenzyme F420 binding
FORC6_RS21735	COG3721	Heme iron utilization protein
FORC6_RS21745	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
FORC6_RS21750	COG0811	peptide transport
FORC6_RS21755	COG0848	biopolymer transport protein
FORC6_RS21765	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC6_RS21770	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FORC6_RS21815	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FORC6_RS21820	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FORC6_RS21825	COG3217	Mosc domain protein beta barrel domain protein
FORC6_RS21825	COG3217	Mosc domain protein beta barrel domain protein
FORC6_RS21825	COG0633	Ferredoxin
FORC6_RS21825	COG0633	Ferredoxin
FORC6_RS21830	COG0418	dihydroorotase activity
FORC6_RS21835	COG2354	Protein conserved in bacteria
FORC6_RS21865	COG3833	ABC-type maltose transport systems, permease component
FORC6_RS21870	COG1175	transmembrane transport
FORC6_RS21880	COG3842	ATPase activity
FORC6_RS21885	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FORC6_RS21910	COG0438	transferase activity, transferring glycosyl groups
FORC6_RS21940	COG3097	Belongs to the UPF0267 family
FORC6_RS21945	COG1309	transcriptional regulator
FORC6_RS21950	COG2130	NADP-dependent
FORC6_RS21960	COG0753	catalase activity
FORC6_RS21965	COG2084	Dehydrogenase
FORC6_RS21970	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FORC6_RS21975	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FORC6_RS21985	COG2207	Transcriptional regulator
FORC6_RS21990	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC6_RS21990	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FORC6_RS21990	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FORC6_RS22005	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FORC6_RS22010	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
FORC6_RS22020	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FORC6_RS22025	COG0569	domain protein
FORC6_RS22035	COG2205	protein histidine kinase activity
FORC6_RS22040	COG1132	(ABC) transporter
FORC6_RS22045	COG4774	siderophore transport
FORC6_RS22050	COG1120	ATPase activity
FORC6_RS22055	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FORC6_RS22100	COG0840	transmembrane signaling receptor activity
FORC6_RS22105	COG0714	Associated with various cellular activities
FORC6_RS22125	COG2304	oxidoreductase activity
FORC6_RS22140	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FORC6_RS22145	COG0581	inorganic phosphate transmembrane transporter activity
FORC6_RS22150	COG0573	inorganic phosphate transmembrane transporter activity
FORC6_RS22180	COG4771	TonB-dependent receptor
FORC6_RS22185	COG1770	oligopeptidase
FORC6_RS22190	COG0513	Belongs to the DEAD box helicase family
FORC6_RS22200	COG1388	LysM domain
FORC6_RS22200	COG1376	ErfK ybiS ycfS ynhG family protein
FORC6_RS22205	COG0415	Belongs to the DNA photolyase family
FORC6_RS22210	COG0789	Transcriptional regulator
FORC6_RS22215	COG3272	Protein of unknown function (DUF1722)
FORC6_RS22220	COG0813	purine-nucleoside phosphorylase activity
FORC6_RS22235	COG3706	GGDEF domain
FORC6_RS22245	COG1566	PFAM secretion protein HlyD family protein
FORC6_RS22250	COG4720	Psort location CytoplasmicMembrane, score
FORC6_RS22255	COG1122	ATPase activity
FORC6_RS22270	COG0348	domain, Protein
FORC6_RS22275	COG0437	4 iron, 4 sulfur cluster binding
FORC6_RS22280	COG1247	-acetyltransferase
FORC6_RS22305	COG1067	ATP-dependent peptidase activity
FORC6_RS22315	COG4172	Belongs to the ABC transporter superfamily
FORC6_RS22320	COG1505	serine-type exopeptidase activity
FORC6_RS22325	COG0583	DNA-binding transcription factor activity
FORC6_RS22330	COG1620	l-lactate permease
FORC6_RS22335	COG1304	FMN binding
FORC6_RS22345	COG0668	transmembrane transport
FORC6_RS22380	COG1063	alcohol dehydrogenase
FORC6_RS22385	COG0156	8-amino-7-oxononanoate synthase activity
FORC6_RS22395	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC6_RS22415	COG0745	RESPONSE REGULATOR receiver
FORC6_RS22440	COG0346	lactoylglutathione lyase activity
FORC6_RS22460	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FORC6_RS22540	COG1987	bacterial-type flagellum assembly
FORC6_RS22550	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FORC6_RS22565	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FORC6_RS22580	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FORC6_RS22585	COG1516	flagellar protein fliS
FORC6_RS22600	COG1580	Controls the rotational direction of flagella during chemotaxis
FORC6_RS22605	COG1191	sigma factor activity
FORC6_RS22610	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FORC6_RS22615	COG1360	Flagellar Motor Protein
FORC6_RS22645	COG1882	Formate acetyltransferase
FORC6_RS22650	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FORC6_RS22655	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FORC6_RS22665	COG0454	-acetyltransferase
FORC6_RS22675	COG2814	Major facilitator Superfamily
FORC6_RS22715	COG0628	permease
FORC6_RS22720	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
FORC6_RS22730	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FORC6_RS22740	COG4628	conserved protein (DUF2132)
FORC6_RS22745	COG0583	DNA-binding transcription factor activity
FORC6_RS22770	COG1686	Belongs to the peptidase S11 family
FORC6_RS22785	COG1054	Belongs to the UPF0176 family
FORC6_RS22790	COG3397	chitin binding
FORC6_RS22795	COG4667	esterase of the alpha-beta hydrolase superfamily
FORC6_RS22800	COG2095	MarC family integral membrane protein
FORC6_RS22825	COG0583	DNA-binding transcription factor activity
FORC6_RS22835	COG1301	dicarboxylic acid transport
FORC6_RS22840	COG3339	Conserved Protein
FORC6_RS22845	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FORC6_RS22850	COG0700	Nucleoside recognition
FORC6_RS22855	COG3366	ferrous iron transmembrane transporter activity
FORC6_RS22870	COG0366	Alpha amylase catalytic
FORC6_RS22875	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FORC6_RS22880	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FORC6_RS22885	COG1640	4-alpha-glucanotransferase
FORC6_RS22890	COG0058	SHG alpha-glucan phosphorylase activity
FORC6_RS22895	COG2909	trisaccharide binding
FORC6_RS22910	COG1999	signal sequence binding
FORC6_RS22920	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC6_RS22920	COG1263	PTS System
FORC6_RS22925	COG1162	GTPase activity
FORC6_RS22930	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
FORC6_RS22940	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
FORC6_RS22950	COG0531	amino acid
FORC6_RS22955	COG1982	Orn Lys Arg decarboxylase major
FORC6_RS22975	COG2356	endonuclease I
FORC6_RS23020	COG0739	heme binding
FORC6_RS23030	COG0612	Peptidase, M16
FORC6_RS23035	COG0840	transmembrane signaling receptor activity
FORC6_RS23040	COG1120	ATPase activity
FORC6_RS23045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC6_RS23050	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC6_RS23055	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FORC6_RS23060	COG4772	TonB-dependent receptor
FORC6_RS23085	COG4264	IucA IucC family
FORC6_RS23090	COG0019	diaminopimelate decarboxylase activity
FORC6_RS23095	COG1653	transport
FORC6_RS23120	COG0826	peptidase U32
FORC6_RS23125	COG1172	Belongs to the binding-protein-dependent transport system permease family
FORC6_RS23130	COG1129	ABC transporter
FORC6_RS23135	COG1879	ABC-type sugar transport system periplasmic component
FORC6_RS23140	COG1069	ribulokinase activity
FORC6_RS23150	COG2160	L-arabinose isomerase activity
FORC6_RS23175	COG1764	response to oxidative stress
FORC6_RS23180	COG1846	Transcriptional regulator
FORC6_RS23190	COG3634	alkyl hydroperoxide reductase activity
FORC6_RS23220	COG1595	DNA-templated transcription, initiation
FORC6_RS23235	COG0583	DNA-binding transcription factor activity
FORC6_RS23240	COG1486	melibiose metabolic process
FORC6_RS23255	COG2258	MOSC domain
FORC6_RS23260	COG0513	Belongs to the DEAD box helicase family
FORC6_RS23275	COG2207	Transcriptional regulator
FORC6_RS23285	COG1132	(ABC) transporter
FORC6_RS23325	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FORC6_RS23350	COG0259	pyridoxamine-phosphate oxidase activity
FORC6_RS23395	COG4166	transmembrane transport
FORC6_RS23410	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FORC6_RS23415	COG1263	PTS System
FORC6_RS23415	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC6_RS23420	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FORC6_RS23425	COG3340	Belongs to the peptidase S51 family
FORC6_RS23445	COG1444	tRNA N-acetyltransferase activity
FORC6_RS23585	COG2165	general secretion pathway protein
FORC6_RS24035	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FORC6_RS24930	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FORC6_RS24930	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
FORC6_RS25090	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FORC6_RS25180	COG3140	Belongs to the UPF0181 family
FORC6_RS25285	COG0583	DNA-binding transcription factor activity
FORC6_RS25315	COG0401	homolog of Blt101
FORC6_RS25365	COG3335	DDE superfamily endonuclease
FORC6_RS25455	COG3335	DDE superfamily endonuclease