locus-tag	class	description
FDV78_RS00015	COG0174	glutamine synthetase
FDV78_RS00025	COG3852	Histidine kinase
FDV78_RS00030	COG2204	response regulator
FDV78_RS00040	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FDV78_RS00070	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FDV78_RS00075	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FDV78_RS00075	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FDV78_RS00090	COG0084	hydrolase, TatD family'
FDV78_RS00095	COG0805	protein transport
FDV78_RS00100	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FDV78_RS00105	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FDV78_RS00110	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FDV78_RS00115	COG3165	ubiquinone biosynthetic process from chorismate
FDV78_RS00120	COG2226	methyltransferase
FDV78_RS00125	COG1322	Protein conserved in bacteria
FDV78_RS00140	COG0628	permease
FDV78_RS00190	COG2823	Periplasmic or secreted lipoprotein
FDV78_RS00200	COG2081	HI0933 family
FDV78_RS00210	COG1528	Iron-storage protein
FDV78_RS00215	COG0589	response to stress
FDV78_RS00230	COG0742	ribosomal rna small subunit methyltransferase
FDV78_RS00235	COG5002	protein histidine kinase activity
FDV78_RS00235	COG5001	Diguanylate cyclase
FDV78_RS00240	COG1522	sequence-specific DNA binding
FDV78_RS00245	COG0339	signal peptide processing
FDV78_RS00250	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FDV78_RS00255	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FDV78_RS00260	COG0583	DNA-binding transcription factor activity
FDV78_RS00265	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FDV78_RS00270	COG0800	Aldolase
FDV78_RS00275	COG2610	gluconate transmembrane transporter activity
FDV78_RS00280	COG3265	gluconokinase activity
FDV78_RS00285	COG0129	dihydroxy-acid dehydratase activity
FDV78_RS00300	COG0583	DNA-binding transcription factor activity
FDV78_RS00305	COG1609	Transcriptional regulator
FDV78_RS00340	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FDV78_RS00350	COG0747	negative chemotaxis
FDV78_RS00355	COG4172	Belongs to the ABC transporter superfamily
FDV78_RS00405	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FDV78_RS00410	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FDV78_RS00415	COG2960	long-chain fatty acid transporting porin activity
FDV78_RS00420	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FDV78_RS00425	COG0583	DNA-binding transcription factor activity
FDV78_RS00460	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FDV78_RS00470	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FDV78_RS00475	COG0408	coproporphyrinogen oxidase activity
FDV78_RS00480	COG0009	L-threonylcarbamoyladenylate synthase
FDV78_RS00485	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FDV78_RS00490	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FDV78_RS00495	COG0551	DNA topoisomerase type I activity
FDV78_RS00500	COG2922	Belongs to the Smg family
FDV78_RS00505	COG0758	DNA mediated transformation
FDV78_RS00515	COG0242	peptide deformylase activity
FDV78_RS00520	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FDV78_RS00525	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FDV78_RS00525	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FDV78_RS00530	COG0569	domain protein
FDV78_RS00535	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FDV78_RS00545	COG1272	protein, Hemolysin III
FDV78_RS00550	COG4326	sporulation control protein
FDV78_RS00560	COG3084	Protein conserved in bacteria
FDV78_RS00570	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FDV78_RS00575	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FDV78_RS00580	COG0204	Acyl-transferase
FDV78_RS00590	COG0606	chelatase, subunit chli
FDV78_RS00600	COG3978	acetolactate synthase activity
FDV78_RS00605	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FDV78_RS00610	COG0129	dihydroxy-acid dehydratase activity
FDV78_RS00620	COG0583	DNA-binding transcription factor activity
FDV78_RS00625	COG2814	Major facilitator Superfamily
FDV78_RS00630	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FDV78_RS00635	COG0765	amino acid transport
FDV78_RS00640	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FDV78_RS00645	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FDV78_RS00650	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FDV78_RS00655	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FDV78_RS00660	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FDV78_RS00665	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FDV78_RS00680	COG0356	it plays a direct role in the translocation of protons across the membrane
FDV78_RS00685	COG3312	ion transport
FDV78_RS00690	COG1475	DNA binding
FDV78_RS00695	COG1192	Involved in chromosome partitioning
FDV78_RS00700	COG0357	Ribosomal RNA small subunit methyltransferase G
FDV78_RS00705	COG0445	tRNA wobble uridine modification
FDV78_RS00710	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FDV78_RS00715	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FDV78_RS00720	COG0706	membrane insertase activity
FDV78_RS00730	COG0594	ribonuclease P activity
FDV78_RS00740	COG1126	abc transporter atp-binding protein
FDV78_RS00755	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FDV78_RS00760	COG0592	DNA-directed DNA polymerase activity
FDV78_RS00765	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FDV78_RS00770	COG0187	DNA topoisomerase II activity
FDV78_RS00780	COG0071	Belongs to the small heat shock protein (HSP20) family
FDV78_RS00785	COG3977	Valine--pyruvate aminotransferase
FDV78_RS00790	COG0366	Alpha amylase catalytic
FDV78_RS00795	COG0751	glycine-tRNA ligase activity
FDV78_RS00800	COG0752	glycyl-tRNA synthetase alpha subunit
FDV78_RS00805	COG2119	membrane
FDV78_RS00815	COG0425	Belongs to the sulfur carrier protein TusA family
FDV78_RS00830	COG0604	alcohol dehydrogenase
FDV78_RS00835	COG0183	Belongs to the thiolase family
FDV78_RS00840	COG1024	Enoyl-CoA hydratase
FDV78_RS00840	COG1250	3-hydroxyacyl-CoA dehydrogenase
FDV78_RS00845	COG1739	Uncharacterized protein family UPF0029
FDV78_RS00850	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FDV78_RS00895	COG3335	DDE superfamily endonuclease
FDV78_RS00910	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FDV78_RS00915	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FDV78_RS00920	COG0352	thiamine-phosphate diphosphorylase activity
FDV78_RS00925	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FDV78_RS00930	COG2104	thiamine diphosphate biosynthetic process
FDV78_RS00935	COG2022	thiamine diphosphate biosynthetic process
FDV78_RS00945	COG0006	proline dipeptidase activity
FDV78_RS00945	COG0006	proline dipeptidase activity
FDV78_RS00975	COG3220	belongs to the UPF0276 family
FDV78_RS00985	COG0210	DNA helicase
FDV78_RS00990	COG0405	Gamma-glutamyltransferase
FDV78_RS00995	COG1280	lysine exporter protein (LysE YggA)
FDV78_RS01005	COG2962	Rard protein
FDV78_RS01010	COG0514	ATP-dependent DNA helicase (RecQ)
FDV78_RS01020	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FDV78_RS01025	COG0248	Ppx GppA phosphatase
FDV78_RS01030	COG0513	Belongs to the DEAD box helicase family
FDV78_RS01035	COG3118	belongs to the thioredoxin family
FDV78_RS01050	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FDV78_RS01055	COG0633	Ferredoxin
FDV78_RS01095	COG3071	HemY protein
FDV78_RS01100	COG2959	enzyme of heme biosynthesis
FDV78_RS01105	COG1587	Uroporphyrinogen-III synthase
FDV78_RS01110	COG0181	hydroxymethylbilane synthase activity
FDV78_RS01115	COG3072	Adenylate cyclase
FDV78_RS01120	COG1965	Belongs to the frataxin family
FDV78_RS01130	COG0019	diaminopimelate decarboxylase activity
FDV78_RS01135	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FDV78_RS01145	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FDV78_RS01150	COG1011	Hydrolase
FDV78_RS01155	COG2199	diguanylate cyclase activity
FDV78_RS01155	COG2200	EAL domain
FDV78_RS01155	COG3287	FIST C domain
FDV78_RS01175	COG0561	phosphatase activity
FDV78_RS01180	COG2267	carboxylic ester hydrolase activity
FDV78_RS01185	COG1280	lysine exporter protein (LysE YggA)
FDV78_RS01190	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FDV78_RS01195	COG0640	Transcriptional regulator
FDV78_RS01200	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FDV78_RS01245	COG2095	MarC family integral membrane protein
FDV78_RS01255	COG0742	ribosomal rna small subunit methyltransferase
FDV78_RS01260	COG0552	protein localization to endoplasmic reticulum
FDV78_RS01265	COG2884	Cell division ATP-binding protein ftsE
FDV78_RS01270	COG2177	Part of the ABC transporter FtsEX involved in
FDV78_RS01280	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FDV78_RS01285	COG0705	Rhomboid family
FDV78_RS01290	COG1580	Controls the rotational direction of flagella during chemotaxis
FDV78_RS01295	COG3161	chorismate lyase activity
FDV78_RS01300	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FDV78_RS01305	COG2937	Belongs to the GPAT DAPAT family
FDV78_RS01310	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FDV78_RS01315	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
FDV78_RS01320	COG0534	Mate efflux family protein
FDV78_RS01325	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FDV78_RS01340	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FDV78_RS01345	COG4206	TonB-dependent receptor
FDV78_RS01355	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FDV78_RS01385	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FDV78_RS01395	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FDV78_RS01430	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FDV78_RS01435	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FDV78_RS01440	COG0250	Participates in transcription elongation, termination and antitermination
FDV78_RS01445	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FDV78_RS01450	COG0081	regulation of translation
FDV78_RS01455	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FDV78_RS01460	COG0222	ribosome binding
FDV78_RS01465	COG0085	RNA polymerase activity
FDV78_RS01470	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FDV78_RS01475	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
FDV78_RS01480	COG2816	NAD+ diphosphatase activity
FDV78_RS01495	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FDV78_RS01500	COG1573	uracil-dna glycosylase
FDV78_RS01505	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FDV78_RS01515	COG1253	flavin adenine dinucleotide binding
FDV78_RS01530	COG0151	Belongs to the GarS family
FDV78_RS01535	COG0138	bifunctional purine biosynthesis protein purh
FDV78_RS01540	COG0789	Transcriptional regulator
FDV78_RS01545	COG3710	Transcriptional regulator
FDV78_RS01550	COG0531	amino acid
FDV78_RS01555	COG1982	Orn Lys Arg decarboxylase major
FDV78_RS01645	COG3706	GGDEF domain
FDV78_RS01650	COG0488	(ABC) transporter
FDV78_RS01655	COG2814	Major facilitator Superfamily
FDV78_RS01660	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FDV78_RS01665	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FDV78_RS01670	COG2264	protein methyltransferase activity
FDV78_RS01675	COG0439	Biotin carboxylase
FDV78_RS01680	COG0511	ligase activity, forming carbon-carbon bonds
FDV78_RS01685	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FDV78_RS01690	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FDV78_RS01705	COG2814	Major facilitator Superfamily
FDV78_RS01710	COG2198	Histidine kinase
FDV78_RS01710	COG0784	Response regulator, receiver
FDV78_RS01710	COG2205	protein histidine kinase activity
FDV78_RS01730	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FDV78_RS01740	COG3263	regulation of cellular component size
FDV78_RS01750	COG4232	protein-disulfide reductase activity
FDV78_RS01755	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FDV78_RS01760	COG1027	Aspartate ammonia-lyase
FDV78_RS01765	COG3030	protein affecting phage T7 exclusion by the F plasmid
FDV78_RS01770	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FDV78_RS01780	COG2205	protein histidine kinase activity
FDV78_RS01785	COG0745	RESPONSE REGULATOR receiver
FDV78_RS01790	COG3678	ATP-independent chaperone mediated protein folding
FDV78_RS01800	COG0205	6-phosphofructokinase activity
FDV78_RS01805	COG0534	Mate efflux family protein
FDV78_RS01815	COG0459	protein refolding
FDV78_RS01830	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FDV78_RS01835	COG1509	lysine 2,3-aminomutase activity
FDV78_RS01840	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FDV78_RS01850	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
FDV78_RS01855	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
FDV78_RS01860	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FDV78_RS01865	COG1053	succinate dehydrogenase
FDV78_RS01870	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
FDV78_RS01890	COG4942	peptidase
FDV78_RS01895	COG1045	serine acetyltransferase
FDV78_RS01900	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FDV78_RS01905	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FDV78_RS01910	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FDV78_RS01915	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FDV78_RS01960	COG0471	metal ion transport
FDV78_RS01965	COG0688	phosphatidylethanolamine metabolic process
FDV78_RS01970	COG1162	GTPase activity
FDV78_RS01975	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FDV78_RS02045	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FDV78_RS02050	COG0802	atpase or kinase
FDV78_RS02055	COG0860	N-Acetylmuramoyl-L-alanine amidase
FDV78_RS02060	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FDV78_RS02065	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FDV78_RS02075	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FDV78_RS02080	COG0330	HflC and HflK could
FDV78_RS02085	COG0330	HflC and HflK could
FDV78_RS02090	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
FDV78_RS02095	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FDV78_RS02100	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
FDV78_RS02105	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FDV78_RS02105	COG1017	nitric oxide dioxygenase activity
FDV78_RS02110	COG1959	2 iron, 2 sulfur cluster binding
FDV78_RS02115	COG0557	exoribonuclease II activity
FDV78_RS02120	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FDV78_RS02125	COG0546	phosphoglycolate phosphatase activity
FDV78_RS02130	COG0180	Tryptophanyl-tRNA synthetase
FDV78_RS02145	COG0512	Glutamine amidotransferase of anthranilate synthase
FDV78_RS02150	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FDV78_RS02160	COG1012	belongs to the aldehyde dehydrogenase family
FDV78_RS02170	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FDV78_RS02175	COG3954	Phosphoribulokinase
FDV78_RS02180	COG3089	Belongs to the UPF0270 family
FDV78_RS02185	COG0429	hydrolase of the alpha beta-hydrolase fold
FDV78_RS02195	COG0488	(ABC) transporter
FDV78_RS02200	COG2249	NAD(P)H dehydrogenase (quinone) activity
FDV78_RS02215	COG1047	Peptidyl-prolyl cis-trans
FDV78_RS02220	COG1446	asparaginase
FDV78_RS02225	COG2900	Belongs to the SlyX family
FDV78_RS02235	COG0545	Peptidyl-prolyl cis-trans isomerase
FDV78_RS02240	COG2964	Protein conserved in bacteria
FDV78_RS02245	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
FDV78_RS02250	COG2923	Belongs to the DsrF TusC family
FDV78_RS02255	COG2168	tRNA wobble position uridine thiolation
FDV78_RS02265	COG0049	tRNA binding
FDV78_RS02270	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FDV78_RS02275	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FDV78_RS02280	COG2906	2 iron, 2 sulfur cluster binding
FDV78_RS02290	COG0281	malic enzyme
FDV78_RS02300	COG0626	cystathionine gamma-synthase activity
FDV78_RS02305	COG0527	aspartate kinase activity
FDV78_RS02305	COG0460	homoserine dehydrogenase
FDV78_RS02310	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FDV78_RS02320	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FDV78_RS02325	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FDV78_RS02330	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FDV78_RS02335	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FDV78_RS02340	COG0137	argininosuccinate synthase activity
FDV78_RS02345	COG0165	Argininosuccinate lyase
FDV78_RS02345	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FDV78_RS02355	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FDV78_RS02355	COG0678	peroxiredoxin activity
FDV78_RS02365	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FDV78_RS02395	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FDV78_RS02400	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FDV78_RS02410	COG0338	D12 class N6 adenine-specific DNA methyltransferase
FDV78_RS02415	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FDV78_RS02420	COG0360	Binds together with S18 to 16S ribosomal RNA
FDV78_RS02425	COG2965	DNA replication, synthesis of RNA primer
FDV78_RS02435	COG0359	binds to the 23S rRNA
FDV78_RS02450	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FDV78_RS02460	COG0432	Pfam Uncharacterised protein family UPF0047
FDV78_RS02465	COG0166	Belongs to the GPI family
FDV78_RS02475	COG0735	belongs to the Fur family
FDV78_RS02480	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FDV78_RS02500	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FDV78_RS02505	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FDV78_RS02510	COG0175	sulfate reduction
FDV78_RS02580	COG0646	methionine synthase
FDV78_RS02580	COG1410	methionine synthase
FDV78_RS02590	COG0527	aspartate kinase activity
FDV78_RS02595	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FDV78_RS02605	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FDV78_RS02620	COG0629	single-stranded DNA binding
FDV78_RS02625	COG2200	EAL domain
FDV78_RS02625	COG2199	diguanylate cyclase activity
FDV78_RS02650	COG3267	Type II secretory pathway component ExeA
FDV78_RS02650	COG3409	Peptidoglycan-binding domain 1 protein
FDV78_RS02660	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FDV78_RS02665	COG1459	type II secretion system
FDV78_RS02710	COG1077	Cell shape determining protein MreB Mrl
FDV78_RS02715	COG1792	Involved in formation and maintenance of cell shape
FDV78_RS02720	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FDV78_RS02725	COG0424	maF-like protein
FDV78_RS02730	COG1530	ribonuclease E activity
FDV78_RS02735	COG3164	Protein of unknown function
FDV78_RS02740	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FDV78_RS02745	COG0312	modulator of DNA gyrase
FDV78_RS02750	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FDV78_RS02755	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FDV78_RS02765	COG0564	pseudouridine synthase activity
FDV78_RS02770	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FDV78_RS02775	COG3028	Belongs to the UPF0307 family
FDV78_RS02780	COG0312	modulator of DNA gyrase
FDV78_RS02785	COG2239	Acts as a magnesium transporter
FDV78_RS02790	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FDV78_RS02795	COG1660	Displays ATPase and GTPase activities
FDV78_RS02800	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FDV78_RS02805	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FDV78_RS02815	COG1137	ATPase activity
FDV78_RS02820	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FDV78_RS02830	COG0517	IMP dehydrogenase activity
FDV78_RS02830	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FDV78_RS02840	COG1127	ABC transporter
FDV78_RS02845	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FDV78_RS02850	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FDV78_RS02855	COG2854	intermembrane phospholipid transfer
FDV78_RS02865	COG5007	Belongs to the BolA IbaG family
FDV78_RS02870	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FDV78_RS02875	COG0204	Acyl-transferase
FDV78_RS02880	COG0251	oxidation-reduction process
FDV78_RS02885	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
FDV78_RS02890	COG0540	Belongs to the ATCase OTCase family
FDV78_RS02900	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FDV78_RS02905	COG2235	arginine
FDV78_RS02930	COG0525	valine-tRNA ligase activity
FDV78_RS02935	COG2927	DNA polymerase III (CHI subunit)
FDV78_RS02940	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FDV78_RS02945	COG0795	lipopolysaccharide-transporting ATPase activity
FDV78_RS02950	COG0795	lipopolysaccharide-transporting ATPase activity
FDV78_RS02965	COG1028	Short-chain dehydrogenase reductase Sdr
FDV78_RS02975	COG0726	polysaccharide deacetylase
FDV78_RS02980	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FDV78_RS02985	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FDV78_RS02990	COG1447	Phosphotransferase system cellobiose-specific component IIA
FDV78_RS02995	COG1486	melibiose metabolic process
FDV78_RS03000	COG3394	polysaccharide catabolic process
FDV78_RS03010	COG3437	response regulator, receiver
FDV78_RS03055	COG1012	belongs to the aldehyde dehydrogenase family
FDV78_RS03085	COG0840	transmembrane signaling receptor activity
FDV78_RS03125	COG0741	lytic transglycosylase activity
FDV78_RS03130	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
FDV78_RS03140	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FDV78_RS03150	COG2066	Belongs to the glutaminase family
FDV78_RS03155	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FDV78_RS03160	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FDV78_RS03170	COG1872	DUF167
FDV78_RS03175	COG0762	integral membrane protein
FDV78_RS03180	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FDV78_RS03185	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FDV78_RS03200	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FDV78_RS03205	COG1678	Uncharacterized ACR, COG1678
FDV78_RS03210	COG0189	ligase activity
FDV78_RS03215	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FDV78_RS03220	COG2356	endonuclease I
FDV78_RS03225	COG3091	SprT-like family
FDV78_RS03235	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FDV78_RS03240	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FDV78_RS03245	COG0583	DNA-binding transcription factor activity
FDV78_RS03250	COG4771	TonB-dependent receptor
FDV78_RS03255	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FDV78_RS03260	COG0126	phosphoglycerate kinase activity
FDV78_RS03265	COG0191	fructose-bisphosphate aldolase activity
FDV78_RS03270	COG0668	transmembrane transport
FDV78_RS03275	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FDV78_RS03295	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FDV78_RS03300	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FDV78_RS03305	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FDV78_RS03315	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
FDV78_RS03320	COG3079	Belongs to the UPF0149 family
FDV78_RS03325	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FDV78_RS03330	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FDV78_RS03345	COG0354	folic acid binding
FDV78_RS03350	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FDV78_RS03355	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FDV78_RS03360	COG1595	DNA-templated transcription, initiation
FDV78_RS03365	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
FDV78_RS03375	COG3086	response to oxidative stress
FDV78_RS03380	COG0481	GTPase activity
FDV78_RS03390	COG0571	ribonuclease III activity
FDV78_RS03395	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FDV78_RS03400	COG1381	Involved in DNA repair and RecF pathway recombination
FDV78_RS03405	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FDV78_RS03410	COG0736	holo-[acyl-carrier-protein] synthase activity
FDV78_RS03420	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FDV78_RS03425	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FDV78_RS03430	COG3956	TIGRFAM MazG family protein
FDV78_RS03435	COG0504	CTP synthase activity
FDV78_RS03440	COG0148	phosphopyruvate hydratase activity
FDV78_RS03445	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
FDV78_RS03450	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FDV78_RS03455	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FDV78_RS03460	COG0585	pseudouridine synthase activity
FDV78_RS03465	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FDV78_RS03470	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FDV78_RS03480	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FDV78_RS03485	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FDV78_RS03490	COG0582	viral genome integration into host DNA
FDV78_RS03545	COG0745	RESPONSE REGULATOR receiver
FDV78_RS03590	COG2003	Belongs to the UPF0758 family
FDV78_RS03620	COG3501	Rhs element vgr protein
FDV78_RS03635	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FDV78_RS03645	COG1546	Belongs to the CinA family
FDV78_RS03650	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FDV78_RS03655	COG2137	regulation of response to DNA damage stimulus
FDV78_RS03660	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FDV78_RS03665	COG0527	aspartate kinase activity
FDV78_RS03725	COG3630	sodium ion export across plasma membrane
FDV78_RS03730	COG5016	pyruvate
FDV78_RS03730	COG0511	ligase activity, forming carbon-carbon bonds
FDV78_RS03735	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
FDV78_RS03740	COG1063	alcohol dehydrogenase
FDV78_RS03745	COG1238	metal cluster binding
FDV78_RS03750	COG0612	Peptidase, M16
FDV78_RS03755	COG2918	glutathione biosynthetic process
FDV78_RS03765	COG1854	S-ribosylhomocysteine lyase activity
FDV78_RS03770	COG4536	flavin adenine dinucleotide binding
FDV78_RS03775	COG4137	Cytochrome C assembly protein
FDV78_RS03780	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FDV78_RS03785	COG0228	four-way junction DNA binding
FDV78_RS03790	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FDV78_RS03795	COG0336	Belongs to the RNA methyltransferase TrmD family
FDV78_RS03800	COG0335	large ribosomal subunit rRNA binding
FDV78_RS03805	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FDV78_RS03810	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
FDV78_RS03815	COG0237	dephospho-CoA kinase activity
FDV78_RS03825	COG1459	type II secretion system
FDV78_RS03830	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FDV78_RS03840	COG0157	Belongs to the NadC ModD family
FDV78_RS03850	COG2186	Transcriptional regulator
FDV78_RS03855	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FDV78_RS03860	COG0508	dehydrogenase complex catalyzes the overall conversion of
FDV78_RS03865	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FDV78_RS03880	COG0288	reversible hydration of carbon dioxide
FDV78_RS03885	COG0659	secondary active sulfate transmembrane transporter activity
FDV78_RS03890	COG1131	(ABC) transporter
FDV78_RS03895	COG0842	Transport permease protein
FDV78_RS03900	COG1560	Kdo2-lipid A biosynthetic process
FDV78_RS03905	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FDV78_RS03910	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FDV78_RS03915	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FDV78_RS03925	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FDV78_RS03935	COG1489	DNA binding
FDV78_RS03940	COG1643	Atp-dependent helicase
FDV78_RS03985	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FDV78_RS03990	COG1752	Esterase of the alpha-beta hydrolase superfamily
FDV78_RS03995	COG1049	propionate catabolic process, 2-methylcitrate cycle
FDV78_RS04000	COG3112	Uncharacterised protein family (UPF0231)
FDV78_RS04010	COG0004	ammonium transporteR
FDV78_RS04015	COG1840	ABC-type Fe3 transport system, periplasmic component
FDV78_RS04025	COG3842	ATPase activity
FDV78_RS04030	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FDV78_RS04045	COG2971	BadF BadG BcrA BcrD
FDV78_RS04055	COG4608	Belongs to the ABC transporter superfamily
FDV78_RS04060	COG0444	Belongs to the ABC transporter superfamily
FDV78_RS04065	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FDV78_RS04075	COG0747	negative chemotaxis
FDV78_RS04080	COG2198	Histidine kinase
FDV78_RS04080	COG0784	Response regulator, receiver
FDV78_RS04080	COG2205	protein histidine kinase activity
FDV78_RS04080	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FDV78_RS04085	COG2813	Specifically methylates the guanine in position
FDV78_RS04090	COG0628	permease
FDV78_RS04095	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FDV78_RS04100	COG0316	Belongs to the HesB IscA family
FDV78_RS04110	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FDV78_RS04115	COG0739	heme binding
FDV78_RS04120	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FDV78_RS04130	COG2027	D-alanyl-D-alanine carboxypeptidase
FDV78_RS04135	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FDV78_RS04140	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FDV78_RS04145	COG1534	Rna-binding protein
FDV78_RS04150	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FDV78_RS04155	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FDV78_RS04160	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FDV78_RS04165	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FDV78_RS04170	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FDV78_RS04185	COG0779	Required for maturation of 30S ribosomal subunits
FDV78_RS04190	COG0195	Participates in both transcription termination and antitermination
FDV78_RS04195	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FDV78_RS04200	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FDV78_RS04205	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FDV78_RS04210	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FDV78_RS04215	COG1185	polyribonucleotide nucleotidyltransferase activity
FDV78_RS04230	COG0534	Mate efflux family protein
FDV78_RS04235	COG0826	peptidase U32
FDV78_RS04240	COG0826	peptidase U32
FDV78_RS04250	COG3154	lipid carrier protein
FDV78_RS04255	COG3153	acetyltransferase
FDV78_RS04275	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FDV78_RS04285	COG0084	hydrolase, TatD family'
FDV78_RS04290	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FDV78_RS04295	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FDV78_RS04300	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FDV78_RS04305	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FDV78_RS04310	COG0813	purine-nucleoside phosphorylase activity
FDV78_RS04320	COG0560	Phosphoserine phosphatase
FDV78_RS04330	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FDV78_RS04335	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FDV78_RS04340	COG0583	DNA-binding transcription factor activity
FDV78_RS04350	COG1022	Amp-dependent synthetase and ligase
FDV78_RS04355	COG2169	Transcriptional regulator
FDV78_RS04380	COG4964	Belongs to the GSP D family
FDV78_RS04440	COG0583	DNA-binding transcription factor activity
FDV78_RS04445	COG0531	amino acid
FDV78_RS04450	COG2731	YhcH YjgK YiaL family protein
FDV78_RS04455	COG3250	beta-galactosidase activity
FDV78_RS04460	COG1609	Transcriptional regulator
FDV78_RS04465	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FDV78_RS04475	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FDV78_RS04480	COG2017	converts alpha-aldose to the beta-anomer
FDV78_RS04495	COG2211	Major facilitator Superfamily
FDV78_RS04500	COG1609	Transcriptional regulator
FDV78_RS04505	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FDV78_RS04520	COG0598	Magnesium transport protein CorA
FDV78_RS04525	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FDV78_RS04530	COG1349	DNA-binding transcription factor activity
FDV78_RS04535	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FDV78_RS04540	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FDV78_RS04545	COG2271	Major facilitator Superfamily
FDV78_RS04550	COG0584	glycerophosphoryl diester phosphodiesterase
FDV78_RS04555	COG2171	N-acyltransferase activity
FDV78_RS04560	COG3141	response to X-ray
FDV78_RS04580	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FDV78_RS04585	COG1074	ATP-dependent DNA helicase activity
FDV78_RS04590	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FDV78_RS04600	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FDV78_RS04600	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FDV78_RS04610	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FDV78_RS04615	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FDV78_RS04620	COG2166	iron-sulfur cluster assembly
FDV78_RS04625	COG3706	GGDEF domain
FDV78_RS04630	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FDV78_RS04635	COG0693	protein deglycase activity
FDV78_RS04640	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FDV78_RS04660	COG1595	DNA-templated transcription, initiation
FDV78_RS04680	COG3056	Lipoprotein
FDV78_RS04685	COG2813	Specifically methylates the guanine in position
FDV78_RS04690	COG0271	Belongs to the BolA IbaG family
FDV78_RS04695	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FDV78_RS04700	COG1805	sodium ion transport
FDV78_RS04705	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FDV78_RS04710	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FDV78_RS04715	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FDV78_RS04720	COG2871	sodium ion transport
FDV78_RS04725	COG1477	protein flavinylation
FDV78_RS04765	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FDV78_RS04785	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FDV78_RS04790	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FDV78_RS04815	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FDV78_RS04820	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FDV78_RS04825	COG0514	ATP-dependent DNA helicase (RecQ)
FDV78_RS04830	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FDV78_RS04845	COG0733	neurotransmitter:sodium symporter activity
FDV78_RS04865	COG0442	prolyl-tRNA aminoacylation
FDV78_RS04870	COG1720	tRNA m6t6A37 methyltransferase activity
FDV78_RS04875	COG0254	rRNA binding
FDV78_RS04885	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
FDV78_RS04890	COG1671	Belongs to the UPF0178 family
FDV78_RS04915	COG3098	single-species biofilm formation
FDV78_RS04920	COG0564	pseudouridine synthase activity
FDV78_RS04930	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FDV78_RS04935	COG0024	Methionine aminopeptidase
FDV78_RS04940	COG0052	Belongs to the universal ribosomal protein uS2 family
FDV78_RS04945	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FDV78_RS04950	COG0528	UMP kinase activity
FDV78_RS04955	COG0233	cytoplasmic translational termination
FDV78_RS04960	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FDV78_RS04965	COG0575	Belongs to the CDS family
FDV78_RS04970	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FDV78_RS04975	COG0750	zinc metalloprotease
FDV78_RS04985	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
FDV78_RS04990	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FDV78_RS04995	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FDV78_RS05000	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FDV78_RS05005	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FDV78_RS05010	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FDV78_RS05015	COG0587	DNA-directed DNA polymerase activity
FDV78_RS05020	COG0825	malonyl-CoA metabolic process
FDV78_RS05025	COG0037	tRNA processing
FDV78_RS05035	COG0347	Belongs to the P(II) protein family
FDV78_RS05040	COG3021	interspecies interaction between organisms
FDV78_RS05050	COG0741	lytic transglycosylase activity
FDV78_RS05050	COG1388	LysM domain
FDV78_RS05055	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FDV78_RS05060	COG2226	methyltransferase
FDV78_RS05065	COG0328	RNA-DNA hybrid ribonuclease activity
FDV78_RS05070	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FDV78_RS05090	COG0456	acetyltransferase
FDV78_RS05100	COG1960	acyl-CoA dehydrogenase activity
FDV78_RS05105	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FDV78_RS05110	COG0121	glutamine amidotransferase
FDV78_RS05115	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FDV78_RS05120	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FDV78_RS05125	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FDV78_RS05130	COG2233	PERMEase
FDV78_RS05150	COG1393	Belongs to the ArsC family
FDV78_RS05155	COG4783	chaperone-mediated protein folding
FDV78_RS05170	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FDV78_RS05175	COG2716	regulation of RNA biosynthetic process
FDV78_RS05180	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FDV78_RS05200	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FDV78_RS05205	COG1393	Belongs to the ArsC family
FDV78_RS05230	COG2837	iron assimilation
FDV78_RS05235	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FDV78_RS05240	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FDV78_RS05245	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FDV78_RS05250	COG1334	flagellar protein FlaG
FDV78_RS05255	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FDV78_RS05265	COG1516	flagellar protein fliS
FDV78_RS05275	COG4191	Histidine kinase
FDV78_RS05285	COG1677	Flagellar hook-basal body complex protein FliE
FDV78_RS05295	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FDV78_RS05345	COG1987	bacterial-type flagellum assembly
FDV78_RS05350	COG1684	flagellar biosynthetic protein fliR
FDV78_RS05385	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
FDV78_RS05390	COG0643	Histidine kinase
FDV78_RS05390	COG0784	Response regulator, receiver
FDV78_RS05390	COG2198	Histidine kinase
FDV78_RS05395	COG2201	protein-glutamate methylesterase activity
FDV78_RS05400	COG1192	Involved in chromosome partitioning
FDV78_RS05410	COG0835	chemotaxis
FDV78_RS05420	COG4133	protoheme IX ABC transporter activity
FDV78_RS05425	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FDV78_RS05430	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FDV78_RS05435	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FDV78_RS05440	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
FDV78_RS05445	COG1138	Cytochrome C-type biogenesis protein
FDV78_RS05450	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FDV78_RS05465	COG2853	Lipoprotein
FDV78_RS05475	COG2067	long-chain fatty acid transport protein
FDV78_RS05490	COG0183	Belongs to the thiolase family
FDV78_RS05495	COG1024	Enoyl-CoA hydratase
FDV78_RS05495	COG1250	3-hydroxyacyl-CoA dehydrogenase
FDV78_RS05510	COG2062	phosphohistidine phosphatase, SixA
FDV78_RS05515	COG2840	Smr protein MutS2
FDV78_RS05520	COG2890	protein-(glutamine-N5) methyltransferase activity
FDV78_RS05525	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FDV78_RS05530	COG2860	membrane
FDV78_RS05535	COG3101	peptidyl-lysine hydroxylation
FDV78_RS05545	COG0431	NADPH-dependent FMN reductase
FDV78_RS05550	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FDV78_RS05550	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FDV78_RS05555	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FDV78_RS05560	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FDV78_RS05565	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FDV78_RS05575	COG0101	tRNA pseudouridine synthase activity
FDV78_RS05580	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FDV78_RS05585	COG0285	dihydrofolate synthase activity
FDV78_RS05590	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
FDV78_RS05595	COG1286	toxin biosynthetic process
FDV78_RS05600	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FDV78_RS05605	COG0583	DNA-binding transcription factor activity
FDV78_RS05610	COG0745	RESPONSE REGULATOR receiver
FDV78_RS05615	COG2832	Protein of unknown function (DUF454)
FDV78_RS05620	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FDV78_RS05630	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FDV78_RS05635	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FDV78_RS05640	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FDV78_RS05645	COG0814	amino acid
FDV78_RS05650	COG0251	oxidation-reduction process
FDV78_RS05655	COG3681	Belongs to the UPF0597 family
FDV78_RS05670	COG2261	transglycosylase associated protein
FDV78_RS05675	COG2983	Belongs to the UPF0260 family
FDV78_RS05680	COG0668	transmembrane transport
FDV78_RS05690	COG0346	lactoylglutathione lyase activity
FDV78_RS05700	COG1785	Belongs to the alkaline phosphatase family
FDV78_RS05715	COG2226	methyltransferase
FDV78_RS05730	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FDV78_RS05735	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FDV78_RS05745	COG3139	Protein of unknown function (DUF1315)
FDV78_RS05750	COG0252	asparaginase activity
FDV78_RS05755	COG0616	signal peptide processing
FDV78_RS05760	COG1902	pentaerythritol trinitrate reductase activity
FDV78_RS05760	COG0446	pyridine nucleotide-disulphide oxidoreductase
FDV78_RS05765	COG0778	Nitroreductase
FDV78_RS05770	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FDV78_RS05785	COG0123	including yeast histone deacetylase and acetoin utilization protein
FDV78_RS05800	COG2801	Transposase and inactivated derivatives
FDV78_RS05815	COG0582	viral genome integration into host DNA
FDV78_RS05850	COG3083	sulfuric ester hydrolase activity
FDV78_RS05855	COG3082	Protein of unknown function (DUF1414)
FDV78_RS05860	COG3081	Nucleoid-associated protein
FDV78_RS05875	COG1757	Na H antiporter
FDV78_RS05880	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FDV78_RS05885	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FDV78_RS05890	COG2095	MarC family integral membrane protein
FDV78_RS05895	COG1012	belongs to the aldehyde dehydrogenase family
FDV78_RS05895	COG1454	alcohol dehydrogenase
FDV78_RS05915	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FDV78_RS05925	COG2056	Na+-H+ antiporter family
FDV78_RS05930	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FDV78_RS05935	COG2885	chlorophyll binding
FDV78_RS05945	COG0346	lactoylglutathione lyase activity
FDV78_RS05950	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FDV78_RS05955	COG4660	Part of a membrane complex involved in electron transport
FDV78_RS05960	COG4659	FMN binding
FDV78_RS05965	COG4658	electron transport chain
FDV78_RS05970	COG4656	Part of a membrane complex involved in electron transport
FDV78_RS05975	COG2878	Part of a membrane complex involved in electron transport
FDV78_RS05980	COG4657	Part of a membrane complex involved in electron transport
FDV78_RS06100	COG2003	Belongs to the UPF0758 family
FDV78_RS06130	COG0582	viral genome integration into host DNA
FDV78_RS06140	COG0556	nucleotide-excision repair
FDV78_RS06145	COG2204	response regulator
FDV78_RS06150	COG2198	Histidine kinase
FDV78_RS06155	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FDV78_RS06160	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FDV78_RS06165	COG0521	Mo-molybdopterin cofactor biosynthetic process
FDV78_RS06170	COG0315	cyclic pyranopterin monophosphate synthase activity
FDV78_RS06175	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FDV78_RS06180	COG0314	molybdopterin synthase activity
FDV78_RS06190	COG0601	transmembrane transport
FDV78_RS06195	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FDV78_RS06200	COG0444	Belongs to the ABC transporter superfamily
FDV78_RS06210	COG0435	Glutathione S-transferase
FDV78_RS06220	COG3174	membrane
FDV78_RS06225	COG0857	belongs to the CobB CobQ family
FDV78_RS06225	COG0280	phosphate acetyltransferase
FDV78_RS06230	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FDV78_RS06235	COG3092	negative regulation of chromosome organization
FDV78_RS06245	COG4120	Belongs to the binding-protein-dependent transport system permease family
FDV78_RS06250	COG1122	ATPase activity
FDV78_RS06255	COG0366	Alpha amylase catalytic
FDV78_RS06265	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FDV78_RS06270	COG3318	Belongs to the UPF0149 family
FDV78_RS06270	COG3012	SEC-C Motif Domain Protein
FDV78_RS06275	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FDV78_RS06280	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FDV78_RS06285	COG2186	Transcriptional regulator
FDV78_RS06295	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FDV78_RS06295	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FDV78_RS06300	COG0489	protein tyrosine kinase activity
FDV78_RS06305	COG0572	uridine kinase
FDV78_RS06315	COG2801	Transposase and inactivated derivatives
FDV78_RS06320	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
FDV78_RS06325	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FDV78_RS06330	COG0659	secondary active sulfate transmembrane transporter activity
FDV78_RS06335	COG1530	ribonuclease E activity
FDV78_RS06340	COG0564	pseudouridine synthase activity
FDV78_RS06345	COG0424	maF-like protein
FDV78_RS06350	COG1399	metal-binding, possibly nucleic acid-binding protein
FDV78_RS06360	COG0416	fatty acid biosynthetic process
FDV78_RS06365	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FDV78_RS06395	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FDV78_RS06400	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FDV78_RS06410	COG0084	hydrolase, TatD family'
FDV78_RS06415	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FDV78_RS06415	COG1263	PTS System
FDV78_RS06430	COG0733	neurotransmitter:sodium symporter activity
FDV78_RS06445	COG4667	esterase of the alpha-beta hydrolase superfamily
FDV78_RS06450	COG0469	pyruvate kinase activity
FDV78_RS06455	COG1940	carbohydrate kinase activity
FDV78_RS06460	COG0835	chemotaxis
FDV78_RS06460	COG0784	Response regulator, receiver
FDV78_RS06465	COG0587	DNA-directed DNA polymerase activity
FDV78_RS06480	COG1028	Short-chain dehydrogenase reductase Sdr
FDV78_RS06485	COG0616	signal peptide processing
FDV78_RS06490	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FDV78_RS06495	COG0539	negative regulation of cytoplasmic translation
FDV78_RS06505	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
FDV78_RS06510	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
FDV78_RS06515	COG0284	orotidine-5'-phosphate decarboxylase activity
FDV78_RS06520	COG4166	transmembrane transport
FDV78_RS06545	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FDV78_RS06555	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FDV78_RS06555	COG3008	intermembrane lipid transfer
FDV78_RS06560	COG2995	paraquat-inducible protein a
FDV78_RS06565	COG3258	Cytochrome c
FDV78_RS06570	COG2863	cytochrome
FDV78_RS06610	COG4232	protein-disulfide reductase activity
FDV78_RS06615	COG3118	belongs to the thioredoxin family
FDV78_RS06635	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FDV78_RS06645	COG1136	(ABC) transporter
FDV78_RS06645	COG0577	efflux transmembrane transporter activity
FDV78_RS06650	COG1136	(ABC) transporter
FDV78_RS06650	COG0577	efflux transmembrane transporter activity
FDV78_RS06655	COG0577	efflux transmembrane transporter activity
FDV78_RS06655	COG1136	(ABC) transporter
FDV78_RS06750	COG3850	Histidine kinase
FDV78_RS06750	COG5002	protein histidine kinase activity
FDV78_RS06755	COG0745	RESPONSE REGULATOR receiver
FDV78_RS06760	COG0840	transmembrane signaling receptor activity
FDV78_RS06765	COG1032	radical SAM domain protein
FDV78_RS06770	COG5001	Diguanylate cyclase
FDV78_RS06770	COG4251	negative regulation of phosphorylation
FDV78_RS06770	COG3706	GGDEF domain
FDV78_RS06770	COG2203	Gaf domain
FDV78_RS06785	COG0583	DNA-binding transcription factor activity
FDV78_RS06790	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FDV78_RS06800	COG2350	Protein conserved in bacteria
FDV78_RS06810	COG2917	probably involved in intracellular septation
FDV78_RS06830	COG1301	dicarboxylic acid transport
FDV78_RS06835	COG0318	PFAM AMP-dependent synthetase and ligase
FDV78_RS06840	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FDV78_RS06845	COG0159	tryptophan synthase activity
FDV78_RS06850	COG0133	tryptophan synthase activity
FDV78_RS06855	COG0134	indole-3-glycerol-phosphate synthase activity
FDV78_RS06855	COG0135	phosphoribosylanthranilate isomerase activity
FDV78_RS06860	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FDV78_RS06865	COG0512	Glutamine amidotransferase of anthranilate synthase
FDV78_RS06870	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FDV78_RS06880	COG0613	PHP domain protein
FDV78_RS06885	COG0009	L-threonylcarbamoyladenylate synthase
FDV78_RS06895	COG1187	pseudouridine synthase activity
FDV78_RS06900	COG3099	Belongs to the UPF0263 family
FDV78_RS06905	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FDV78_RS06915	COG0417	DNA replication proofreading
FDV78_RS06920	COG2197	response regulator
FDV78_RS06925	COG0322	excinuclease ABC activity
FDV78_RS06965	COG0019	diaminopimelate decarboxylase activity
FDV78_RS06990	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FDV78_RS06995	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FDV78_RS07000	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FDV78_RS07020	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
FDV78_RS07030	COG0437	4 iron, 4 sulfur cluster binding
FDV78_RS07035	COG3301	Polysulphide reductase, NrfD
FDV78_RS07040	COG1138	Cytochrome C-type biogenesis protein
FDV78_RS07050	COG4235	cytochrome complex assembly
FDV78_RS07050	COG3088	subunit of a heme lyase
FDV78_RS07060	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FDV78_RS07085	COG2989	Protein conserved in bacteria
FDV78_RS07090	COG3108	Peptidase M15
FDV78_RS07095	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FDV78_RS07110	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FDV78_RS07135	COG1846	Transcriptional regulator
FDV78_RS07140	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FDV78_RS07145	COG0840	transmembrane signaling receptor activity
FDV78_RS07165	COG1448	Aminotransferase
FDV78_RS07180	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FDV78_RS07190	COG0017	Asparaginyl-tRNA synthetase
FDV78_RS07195	COG0840	transmembrane signaling receptor activity
FDV78_RS07200	COG0582	viral genome integration into host DNA
FDV78_RS07225	COG5532	Uncharacterized conserved protein (DUF2303)
FDV78_RS07260	COG0751	glycine-tRNA ligase activity
FDV78_RS07530	COG0720	synthase
FDV78_RS07540	COG2200	EAL domain
FDV78_RS07550	COG1760	l-serine dehydratase
FDV78_RS07555	COG0814	amino acid
FDV78_RS07560	COG0494	nUDIX hydrolase
FDV78_RS07570	COG2205	protein histidine kinase activity
FDV78_RS07570	COG0784	Response regulator, receiver
FDV78_RS07575	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FDV78_RS07590	COG3106	COG3106 Predicted ATPase
FDV78_RS07595	COG3768	UPF0283 membrane protein
FDV78_RS07605	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FDV78_RS07720	COG1444	tRNA N-acetyltransferase activity
FDV78_RS08040	COG0456	acetyltransferase
FDV78_RS08140	COG0346	lactoylglutathione lyase activity
FDV78_RS08215	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FDV78_RS08290	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FDV78_RS08330	COG0346	lactoylglutathione lyase activity
FDV78_RS08435	COG3422	double-strand break repair
FDV78_RS08455	COG0494	nUDIX hydrolase
FDV78_RS08935	COG2801	Transposase and inactivated derivatives
FDV78_RS08965	COG1757	Na H antiporter
FDV78_RS08970	COG0174	glutamine synthetase
FDV78_RS08975	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FDV78_RS08980	COG1396	sequence-specific DNA binding
FDV78_RS08980	COG1917	Cupin 2, conserved barrel domain protein
FDV78_RS08985	COG1012	belongs to the aldehyde dehydrogenase family
FDV78_RS08990	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FDV78_RS09000	COG2957	Belongs to the agmatine deiminase family
FDV78_RS09005	COG1012	belongs to the aldehyde dehydrogenase family
FDV78_RS09010	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FDV78_RS09015	COG1227	inorganic diphosphatase activity
FDV78_RS09020	COG2771	luxR family
FDV78_RS09020	COG2200	EAL domain
FDV78_RS09030	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FDV78_RS09045	COG1846	Transcriptional regulator
FDV78_RS09050	COG2315	Protein conserved in bacteria
FDV78_RS09070	COG0110	maltose O-acetyltransferase activity
FDV78_RS09100	COG3063	Type IV pilus biogenesis stability protein PilW
FDV78_RS09105	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FDV78_RS09115	COG0531	amino acid
FDV78_RS09120	COG1560	Kdo2-lipid A biosynthetic process
FDV78_RS09125	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
FDV78_RS09130	COG1280	lysine exporter protein (LysE YggA)
FDV78_RS09140	COG1115	amino acid carrier protein
FDV78_RS09165	COG1368	sulfuric ester hydrolase activity
FDV78_RS09170	COG0642	Histidine kinase
FDV78_RS09175	COG0745	RESPONSE REGULATOR receiver
FDV78_RS09185	COG1028	Short-chain dehydrogenase reductase Sdr
FDV78_RS09205	COG2113	Glycine betaine
FDV78_RS09210	COG4176	ABC-type proline glycine betaine transport system permease component
FDV78_RS09230	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FDV78_RS09235	COG0456	acetyltransferase
FDV78_RS09240	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FDV78_RS09245	COG0662	Cupin 2, conserved barrel domain protein
FDV78_RS09250	COG0527	aspartate kinase activity
FDV78_RS09255	COG1858	cytochrome C peroxidase
FDV78_RS09270	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FDV78_RS09285	COG3290	protein histidine kinase activity
FDV78_RS09290	COG4565	transcriptional regulatory protein
FDV78_RS09295	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FDV78_RS09300	COG0363	glucosamine-6-phosphate deaminase activity
FDV78_RS09305	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FDV78_RS09315	COG2801	Transposase and inactivated derivatives
FDV78_RS09330	COG3284	Transcriptional regulator
FDV78_RS09335	COG1012	belongs to the aldehyde dehydrogenase family
FDV78_RS09405	COG4669	(LipO)protein
FDV78_RS09425	COG3177	Filamentation induced by cAMP protein fic
FDV78_RS09455	COG1073	alpha beta
FDV78_RS09460	COG1073	alpha beta
FDV78_RS09470	COG4792	protein secretion
FDV78_RS09475	COG4791	protein targeting
FDV78_RS09480	COG4794	Type iii secretion
FDV78_RS09485	COG4790	Type iii secretion
FDV78_RS09555	COG0457	Tetratricopeptide repeat
FDV78_RS09575	COG0730	response to heat
FDV78_RS09605	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FDV78_RS09610	COG0372	Belongs to the citrate synthase family
FDV78_RS09620	COG2828	Protein conserved in bacteria
FDV78_RS09645	COG0561	phosphatase activity
FDV78_RS09650	COG0602	queuosine metabolic process
FDV78_RS09655	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FDV78_RS09660	COG3706	GGDEF domain
FDV78_RS09705	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FDV78_RS09710	COG0840	transmembrane signaling receptor activity
FDV78_RS09715	COG1254	Belongs to the acylphosphatase family
FDV78_RS09720	COG2920	part of a sulfur-relay system
FDV78_RS09730	COG0670	Belongs to the BI1 family
FDV78_RS09735	COG1126	abc transporter atp-binding protein
FDV78_RS09740	COG0765	amino acid transport
FDV78_RS09745	COG4597	amino acid ABC transporter
FDV78_RS09750	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FDV78_RS09760	COG1666	GTP binding
FDV78_RS09765	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FDV78_RS09785	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
FDV78_RS09785	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FDV78_RS09790	COG3008	intermembrane lipid transfer
FDV78_RS09795	COG2995	paraquat-inducible protein a
FDV78_RS09800	COG1132	(ABC) transporter
FDV78_RS09805	COG1956	GAF domain-containing protein
FDV78_RS09810	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
FDV78_RS09825	COG0308	aminopeptidase N
FDV78_RS09835	COG2902	Dehydrogenase
FDV78_RS09840	COG0167	dihydroorotate dehydrogenase activity
FDV78_RS09850	COG0116	Belongs to the methyltransferase superfamily
FDV78_RS09850	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FDV78_RS09875	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FDV78_RS09880	COG1067	ATP-dependent peptidase activity
FDV78_RS09885	COG3120	sequence-specific DNA binding
FDV78_RS09905	COG2205	protein histidine kinase activity
FDV78_RS09905	COG0784	Response regulator, receiver
FDV78_RS09920	COG3278	Belongs to the heme-copper respiratory oxidase family
FDV78_RS09935	COG2010	Cytochrome c
FDV78_RS09945	COG2217	Heavy metal translocating P-type atpase
FDV78_RS09960	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FDV78_RS09965	COG0589	response to stress
FDV78_RS09970	COG0037	tRNA processing
FDV78_RS09990	COG3842	ATPase activity
FDV78_RS10000	COG1177	transmembrane transport
FDV78_RS10010	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FDV78_RS10015	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FDV78_RS10025	COG0004	ammonium transporteR
FDV78_RS10055	COG0437	4 iron, 4 sulfur cluster binding
FDV78_RS10060	COG3383	formate dehydrogenase (NAD+) activity
FDV78_RS10060	COG0243	molybdopterin cofactor binding
FDV78_RS10090	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FDV78_RS10095	COG0488	(ABC) transporter
FDV78_RS10100	COG4191	Histidine kinase
FDV78_RS10105	COG2204	response regulator
FDV78_RS10120	COG3842	ATPase activity
FDV78_RS10125	COG0746	molybdenum cofactor guanylyltransferase activity
FDV78_RS10130	COG0303	'Molybdopterin
FDV78_RS10140	COG1940	carbohydrate kinase activity
FDV78_RS10180	COG3290	protein histidine kinase activity
FDV78_RS10180	COG0840	transmembrane signaling receptor activity
FDV78_RS10185	COG0791	NLP P60 protein
FDV78_RS10195	COG3706	GGDEF domain
FDV78_RS10200	COG2201	protein-glutamate methylesterase activity
FDV78_RS10205	COG3001	Fructosamine kinase
FDV78_RS10215	COG0307	riboflavin synthase, alpha
FDV78_RS10220	COG0534	Mate efflux family protein
FDV78_RS10230	COG1793	dna ligase
FDV78_RS10260	COG2204	response regulator
FDV78_RS10300	COG0438	transferase activity, transferring glycosyl groups
FDV78_RS10305	COG1215	transferase activity, transferring glycosyl groups
FDV78_RS10310	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FDV78_RS10320	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FDV78_RS10335	COG1643	Atp-dependent helicase
FDV78_RS10340	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FDV78_RS10355	COG3302	dmso reductase anchor subunit
FDV78_RS10360	COG0437	4 iron, 4 sulfur cluster binding
FDV78_RS10365	COG0243	molybdopterin cofactor binding
FDV78_RS10405	COG0443	Heat shock 70 kDa protein
FDV78_RS10410	COG0443	Heat shock 70 kDa protein
FDV78_RS10435	COG1132	(ABC) transporter
FDV78_RS10440	COG1132	(ABC) transporter
FDV78_RS10460	COG0814	amino acid
FDV78_RS10470	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FDV78_RS10505	COG2801	Transposase and inactivated derivatives
FDV78_RS10775	COG1522	sequence-specific DNA binding
FDV78_RS10810	COG0515	serine threonine protein kinase
FDV78_RS10835	COG3501	Rhs element vgr protein
FDV78_RS10855	COG2801	Transposase and inactivated derivatives
FDV78_RS10955	COG0739	heme binding
FDV78_RS10960	COG0861	Integral membrane protein TerC family
FDV78_RS10970	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FDV78_RS10975	COG1328	CTP reductase activity
FDV78_RS10980	COG1280	lysine exporter protein (LysE YggA)
FDV78_RS10990	COG5001	Diguanylate cyclase
FDV78_RS10990	COG3300	MHYT domain
FDV78_RS11000	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FDV78_RS11000	COG4191	Histidine kinase
FDV78_RS11005	COG0471	metal ion transport
FDV78_RS11035	COG0583	DNA-binding transcription factor activity
FDV78_RS11040	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
FDV78_RS11100	COG0625	glutathione transferase activity
FDV78_RS11110	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
FDV78_RS11120	COG2195	Cleaves the N-terminal amino acid of tripeptides
FDV78_RS11130	COG0601	transmembrane transport
FDV78_RS11135	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FDV78_RS11140	COG0444	Belongs to the ABC transporter superfamily
FDV78_RS11155	COG3291	Pkd domain containing protein
FDV78_RS11165	COG1177	transmembrane transport
FDV78_RS11170	COG1176	ABC-type spermidine putrescine transport system, permease component I
FDV78_RS11175	COG3842	ATPase activity
FDV78_RS11180	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FDV78_RS11185	COG2423	ornithine cyclodeaminase activity
FDV78_RS11200	COG3938	Belongs to the proline racemase family
FDV78_RS11230	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
FDV78_RS11235	COG1451	nucleotide metabolic process
FDV78_RS11240	COG3475	LICD family
FDV78_RS11245	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FDV78_RS11250	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FDV78_RS11270	COG0583	DNA-binding transcription factor activity
FDV78_RS11290	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
FDV78_RS11295	COG4139	cobalamin transport
FDV78_RS11300	COG2988	succinylglutamate desuccinylase activity
FDV78_RS11320	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FDV78_RS11325	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FDV78_RS11330	COG0702	epimerase
FDV78_RS11340	COG2925	Exonuclease
FDV78_RS11345	COG1380	Effector of murein hydrolase LrgA
FDV78_RS11350	COG1346	cytolysis
FDV78_RS11355	COG0295	cytidine deaminase activity
FDV78_RS11360	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
FDV78_RS11365	COG0500	methyltransferase
FDV78_RS11375	COG0776	regulation of translation
FDV78_RS11385	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FDV78_RS11385	COG0072	phenylalanine-tRNA ligase activity
FDV78_RS11390	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FDV78_RS11395	COG3706	GGDEF domain
FDV78_RS11425	COG0393	Putative heavy-metal-binding
FDV78_RS11435	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FDV78_RS11445	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FDV78_RS11460	COG2188	Transcriptional regulator
FDV78_RS11465	COG1228	amidohydrolase
FDV78_RS11470	COG0010	Belongs to the arginase family
FDV78_RS11475	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FDV78_RS11480	COG2986	histidine ammonia-lyase
FDV78_RS11495	COG0277	FAD linked oxidase domain protein
FDV78_RS11495	COG0247	lactate metabolic process
FDV78_RS11530	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FDV78_RS11545	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
FDV78_RS11550	COG1643	Atp-dependent helicase
FDV78_RS11555	COG0281	malic enzyme
FDV78_RS11560	COG2949	membrane
FDV78_RS11565	COG0471	metal ion transport
FDV78_RS11590	COG0492	ferredoxin-NADP+ reductase activity
FDV78_RS11595	COG4988	ABC transporter
FDV78_RS11600	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FDV78_RS11605	COG3048	D-serine ammonia-lyase activity
FDV78_RS11610	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FDV78_RS11620	COG4191	Histidine kinase
FDV78_RS11620	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FDV78_RS11635	COG3070	regulator of competence-specific genes
FDV78_RS11645	COG2431	L-lysine efflux transmembrane transporter activity
FDV78_RS11655	COG0076	glutamate decarboxylase activity
FDV78_RS11660	COG1737	Transcriptional regulator
FDV78_RS11670	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FDV78_RS11675	COG2985	domain, Protein
FDV78_RS11675	COG3273	potassium ion transport
FDV78_RS11680	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FDV78_RS11695	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FDV78_RS11710	COG4181	ATPase activity
FDV78_RS11715	COG0534	Mate efflux family protein
FDV78_RS11720	COG0702	epimerase
FDV78_RS11725	COG3005	denitrification pathway
FDV78_RS11755	COG2814	Major facilitator Superfamily
FDV78_RS11760	COG1187	pseudouridine synthase activity
FDV78_RS11765	COG1061	Type III restriction enzyme res subunit
FDV78_RS11775	COG0745	RESPONSE REGULATOR receiver
FDV78_RS11780	COG2205	protein histidine kinase activity
FDV78_RS11785	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FDV78_RS11810	COG3313	Fe-S protein
FDV78_RS11835	COG0493	'glutamate synthase
FDV78_RS11845	COG0398	Pfam SNARE associated Golgi protein
FDV78_RS11850	COG4134	Bacterial extracellular solute-binding protein
FDV78_RS11855	COG4135	transport system, permease component
FDV78_RS11860	COG4136	ATPase activity
FDV78_RS11865	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FDV78_RS11875	COG3604	Transcriptional regulator
FDV78_RS11880	COG1151	hydroxylamine reductase activity
FDV78_RS11885	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FDV78_RS11895	COG0564	pseudouridine synthase activity
FDV78_RS11905	COG0733	neurotransmitter:sodium symporter activity
FDV78_RS11915	COG0626	cystathionine gamma-synthase activity
FDV78_RS11920	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
FDV78_RS11925	COG5380	lipid catabolic process
FDV78_RS11930	COG2818	Glycosylase
FDV78_RS11945	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FDV78_RS11950	COG1983	PspC domain protein
FDV78_RS11960	COG1842	Phage shock protein A
FDV78_RS11965	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
FDV78_RS11980	COG4171	peptide transport system, permease
FDV78_RS11990	COG4172	Belongs to the ABC transporter superfamily
FDV78_RS12000	COG1227	inorganic diphosphatase activity
FDV78_RS12015	COG0243	molybdopterin cofactor binding
FDV78_RS12020	COG3005	denitrification pathway
FDV78_RS12025	COG4459	periplasmic nitrate reductase
FDV78_RS12030	COG0390	transport system, permease component
FDV78_RS12040	COG2116	formate transmembrane transporter activity
FDV78_RS12065	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FDV78_RS12070	COG1435	thymidine kinase activity
FDV78_RS12075	COG0215	cysteine-tRNA ligase activity
FDV78_RS12080	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FDV78_RS12085	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FDV78_RS12090	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FDV78_RS12095	COG3012	SEC-C Motif Domain Protein
FDV78_RS12100	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FDV78_RS12100	COG0140	phosphoribosyl-ATP diphosphatase activity
FDV78_RS12105	COG0107	imidazoleglycerol-phosphate synthase activity
FDV78_RS12110	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FDV78_RS12115	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FDV78_RS12120	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FDV78_RS12120	COG0131	Imidazoleglycerol-phosphate dehydratase
FDV78_RS12125	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FDV78_RS12130	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FDV78_RS12135	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FDV78_RS12150	COG1757	Na H antiporter
FDV78_RS12160	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FDV78_RS12170	COG0482	sulfurtransferase activity
FDV78_RS12175	COG2915	High frequency lysogenization protein hflD homolog
FDV78_RS12180	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FDV78_RS12200	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FDV78_RS12215	COG0300	oxidoreductase activity
FDV78_RS12225	COG0501	Belongs to the peptidase M48B family
FDV78_RS12235	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FDV78_RS12245	COG0156	8-amino-7-oxononanoate synthase activity
FDV78_RS12250	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FDV78_RS12255	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FDV78_RS12260	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FDV78_RS12275	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FDV78_RS12280	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FDV78_RS12285	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FDV78_RS12290	COG1674	ftsk spoiiie
FDV78_RS12300	COG0686	Belongs to the AlaDH PNT family
FDV78_RS12310	COG0583	DNA-binding transcription factor activity
FDV78_RS12325	COG3568	Endonuclease Exonuclease Phosphatase
FDV78_RS12350	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FDV78_RS12355	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FDV78_RS12360	COG0840	transmembrane signaling receptor activity
FDV78_RS12400	COG5002	protein histidine kinase activity
FDV78_RS12400	COG0784	Response regulator, receiver
FDV78_RS12410	COG0754	glutathionylspermidine amidase activity
FDV78_RS12420	COG3766	membrane
FDV78_RS12430	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FDV78_RS12435	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
FDV78_RS12440	COG2885	chlorophyll binding
FDV78_RS12445	COG0823	Involved in the tonB-independent uptake of proteins
FDV78_RS12460	COG0811	peptide transport
FDV78_RS12465	COG0824	Thioesterase
FDV78_RS12475	COG4890	Cyd operon protein YbgT
FDV78_RS12480	COG1294	oxidase, subunit
FDV78_RS12485	COG1271	oxidase subunit
FDV78_RS12490	COG2255	four-way junction helicase activity
FDV78_RS12495	COG0632	four-way junction helicase activity
FDV78_RS12500	COG0840	transmembrane signaling receptor activity
FDV78_RS12505	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FDV78_RS12510	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FDV78_RS12515	COG1801	Protein of unknown function DUF72
FDV78_RS12520	COG4106	trans-aconitate 2-methyltransferase activity
FDV78_RS12525	COG0500	methyltransferase
FDV78_RS12530	COG4067	protein conserved in archaea
FDV78_RS12530	COG0189	ligase activity
FDV78_RS12550	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FDV78_RS12555	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
FDV78_RS12560	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
FDV78_RS12565	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FDV78_RS12570	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FDV78_RS12575	COG0745	RESPONSE REGULATOR receiver
FDV78_RS12580	COG3381	protein complex oligomerization
FDV78_RS12585	COG1609	Transcriptional regulator
FDV78_RS12590	COG3070	regulator of competence-specific genes
FDV78_RS12610	COG0297	glycogen (starch) synthase activity
FDV78_RS12615	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FDV78_RS12620	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FDV78_RS12630	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FDV78_RS12640	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FDV78_RS12645	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FDV78_RS12650	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FDV78_RS12660	COG0542	response to heat
FDV78_RS12665	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FDV78_RS12670	COG1278	Cold shock
FDV78_RS12680	COG1187	pseudouridine synthase activity
FDV78_RS12685	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
FDV78_RS12695	COG1199	ATP-dependent helicase activity
FDV78_RS12700	COG0730	response to heat
FDV78_RS12705	COG3923	Primosomal replication protein n
FDV78_RS12715	COG0708	Exodeoxyribonuclease III
FDV78_RS12755	COG1882	Formate acetyltransferase
FDV78_RS12765	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FDV78_RS12775	COG3013	Belongs to the UPF0304 family
FDV78_RS12780	COG2766	serine protein kinase
FDV78_RS12785	COG2718	Belongs to the UPF0229 family
FDV78_RS12790	COG2719	SpoVR family
FDV78_RS12795	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FDV78_RS12805	COG1663	tetraacyldisaccharide 4'-kinase activity
FDV78_RS12810	COG1132	(ABC) transporter
FDV78_RS12815	COG0658	competence protein
FDV78_RS12815	COG2333	competence protein COMEC
FDV78_RS12825	COG4591	ABC-type transport system involved in lipoprotein release permease component
FDV78_RS12830	COG1136	(ABC) transporter
FDV78_RS12835	COG4591	ABC-type transport system involved in lipoprotein release permease component
FDV78_RS12845	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FDV78_RS12860	COG1252	NADH dehydrogenase
FDV78_RS12865	COG3150	esterase
FDV78_RS12890	COG0537	adenosine 5'-monophosphoramidase activity
FDV78_RS12915	COG0517	IMP dehydrogenase activity
FDV78_RS12915	COG0516	GMP reductase activity
FDV78_RS12920	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
FDV78_RS12925	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FDV78_RS12930	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FDV78_RS12940	COG2199	diguanylate cyclase activity
FDV78_RS12955	COG3126	Type III secretion system lipoprotein chaperone (YscW)
FDV78_RS12960	COG1946	Acyl-CoA thioesterase
FDV78_RS12970	COG1522	sequence-specific DNA binding
FDV78_RS12995	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FDV78_RS13045	COG0477	Major facilitator Superfamily
FDV78_RS13050	COG2855	membrane
FDV78_RS13070	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FDV78_RS13075	COG0596	Alpha beta hydrolase
FDV78_RS13080	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
FDV78_RS13085	COG1169	isochorismate synthase
FDV78_RS13090	COG0436	Aminotransferase
FDV78_RS13095	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
FDV78_RS13100	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FDV78_RS13115	COG1555	photosystem II stabilization
FDV78_RS13120	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FDV78_RS13125	COG0776	regulation of translation
FDV78_RS13130	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FDV78_RS13135	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FDV78_RS13145	COG0544	peptidyl-prolyl cis-trans isomerase activity
FDV78_RS13160	COG2204	response regulator
FDV78_RS13170	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FDV78_RS13175	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FDV78_RS13180	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FDV78_RS13185	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FDV78_RS13200	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FDV78_RS13205	COG0569	domain protein
FDV78_RS13210	COG0513	Belongs to the DEAD box helicase family
FDV78_RS13215	COG1253	flavin adenine dinucleotide binding
FDV78_RS13250	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FDV78_RS13255	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FDV78_RS13270	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FDV78_RS13275	COG1216	Glycosyl transferase, family 2
FDV78_RS13280	COG2986	histidine ammonia-lyase
FDV78_RS13315	COG1028	Short-chain dehydrogenase reductase Sdr
FDV78_RS13335	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FDV78_RS13340	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FDV78_RS13345	COG0583	DNA-binding transcription factor activity
FDV78_RS13350	COG2951	lytic endotransglycosylase activity
FDV78_RS13355	COG3100	YcgL domain-containing protein
FDV78_RS13360	COG0850	regulation of cytokinetic process
FDV78_RS13365	COG2894	cell division
FDV78_RS13370	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FDV78_RS13375	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FDV78_RS13380	COG0318	PFAM AMP-dependent synthetase and ligase
FDV78_RS13385	COG2267	carboxylic ester hydrolase activity
FDV78_RS13400	COG1214	PFAM Peptidase M22, glycoprotease
FDV78_RS13405	COG1199	ATP-dependent helicase activity
FDV78_RS13410	COG0788	formyltetrahydrofolate deformylase activity
FDV78_RS13415	COG3102	Protein conserved in bacteria
FDV78_RS13420	COG0018	arginyl-trna synthetase
FDV78_RS13440	COG1918	ferrous iron import across plasma membrane
FDV78_RS13445	COG4977	sequence-specific DNA binding
FDV78_RS13450	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
FDV78_RS13455	COG1121	(ABC) transporter
FDV78_RS13460	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FDV78_RS13470	COG0045	succinate-CoA ligase (ADP-forming) activity
FDV78_RS13475	COG0508	dehydrogenase complex catalyzes the overall conversion of
FDV78_RS13480	COG0567	Dehydrogenase, E1 component
FDV78_RS13485	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FDV78_RS13490	COG1053	succinate dehydrogenase
FDV78_RS13495	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FDV78_RS13510	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FDV78_RS13520	COG0033	Phosphoglucomutase
FDV78_RS13525	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
FDV78_RS13530	COG0596	Alpha beta hydrolase
FDV78_RS13550	COG0735	belongs to the Fur family
FDV78_RS13555	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FDV78_RS13560	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FDV78_RS13560	COG1263	PTS System
FDV78_RS13565	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FDV78_RS13570	COG1846	Transcriptional regulator
FDV78_RS13570	COG1940	carbohydrate kinase activity
FDV78_RS13575	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FDV78_RS13575	COG4651	solute:proton antiporter activity
FDV78_RS13580	COG0367	asparagine synthase
FDV78_RS13585	COG0250	Participates in transcription elongation, termination and antitermination
FDV78_RS13590	COG3104	oligopeptide transport
FDV78_RS13595	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FDV78_RS13600	COG0563	adenylate kinase activity
FDV78_RS13605	COG0326	Molecular chaperone. Has ATPase activity
FDV78_RS13610	COG3710	Transcriptional regulator
FDV78_RS13630	COG0622	Phosphoesterase
FDV78_RS13655	COG1090	epimerase
FDV78_RS13660	COG0300	oxidoreductase activity
FDV78_RS13665	COG3118	belongs to the thioredoxin family
FDV78_RS13670	COG0330	HflC and HflK could
FDV78_RS13690	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FDV78_RS13695	COG3115	cell septum assembly
FDV78_RS13700	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
FDV78_RS13705	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FDV78_RS13710	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FDV78_RS13715	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FDV78_RS13720	COG2190	(PTS) system
FDV78_RS13725	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FDV78_RS13730	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FDV78_RS13735	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FDV78_RS13740	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FDV78_RS13750	COG3951	Flagellar rod assembly protein muramidase FlgJ
FDV78_RS13750	COG1705	Flagellar rod assembly protein muramidase FlgJ
FDV78_RS13755	COG1706	bacterial-type flagellum-dependent cell motility
FDV78_RS13760	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FDV78_RS13770	COG4787	bacterial-type flagellum-dependent cell motility
FDV78_RS13775	COG1749	Flagellar hook protein flgE
FDV78_RS13785	COG1558	bacterial-type flagellum-dependent cell motility
FDV78_RS13790	COG1815	bacterial-type flagellum-dependent cell motility
FDV78_RS13795	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FDV78_RS13800	COG0835	chemotaxis
FDV78_RS13800	COG0784	Response regulator, receiver
FDV78_RS13855	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FDV78_RS13860	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
FDV78_RS13870	COG2217	Heavy metal translocating P-type atpase
FDV78_RS13870	COG2608	mercury ion transmembrane transporter activity
FDV78_RS13905	COG2840	Smr protein MutS2
FDV78_RS13910	COG1187	pseudouridine synthase activity
FDV78_RS13920	COG0737	Belongs to the 5'-nucleotidase family
FDV78_RS13925	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FDV78_RS13930	COG2912	Transglutaminase-like superfamily
FDV78_RS13935	COG3094	Invasion gene expression up-regulator, SirB
FDV78_RS13940	COG2890	protein-(glutamine-N5) methyltransferase activity
FDV78_RS13945	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FDV78_RS13950	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FDV78_RS13955	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
FDV78_RS13960	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FDV78_RS13965	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FDV78_RS13970	COG0193	aminoacyl-tRNA hydrolase activity
FDV78_RS13975	COG0012	GTP binding
FDV78_RS14090	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FDV78_RS14095	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FDV78_RS14100	COG1702	phosphate starvation-inducible protein PhoH
FDV78_RS14105	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FDV78_RS14110	COG4535	Mg2 and Co2 transporter CorC
FDV78_RS14115	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FDV78_RS14120	COG2888	peptidyl-tyrosine sulfation
FDV78_RS14125	COG0495	leucyl-tRNA aminoacylation
FDV78_RS14130	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
FDV78_RS14135	COG1466	dna polymerase III delta subunit
FDV78_RS14140	COG0799	negative regulation of ribosome biogenesis
FDV78_RS14145	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FDV78_RS14150	COG0768	penicillin binding
FDV78_RS14155	COG0772	Belongs to the SEDS family
FDV78_RS14160	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FDV78_RS14165	COG1686	Belongs to the peptidase S11 family
FDV78_RS14170	COG2921	Belongs to the UPF0250 family
FDV78_RS14175	COG0321	lipoyl(octanoyl) transferase activity
FDV78_RS14180	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FDV78_RS14185	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FDV78_RS14205	COG0366	Alpha amylase catalytic
FDV78_RS14210	COG1263	PTS System
FDV78_RS14210	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FDV78_RS14220	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FDV78_RS14225	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FDV78_RS14230	COG2011	ABC-type metal ion transport system permease component
FDV78_RS14235	COG1464	Belongs to the NlpA lipoprotein family
FDV78_RS14240	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
FDV78_RS14250	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FDV78_RS14250	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FDV78_RS14265	COG1611	Belongs to the LOG family
FDV78_RS14270	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FDV78_RS14280	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
FDV78_RS14285	COG2363	Small membrane protein
FDV78_RS14295	COG0583	DNA-binding transcription factor activity
FDV78_RS14300	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FDV78_RS14300	COG0301	tRNA thio-modification
FDV78_RS14305	COG2885	chlorophyll binding
FDV78_RS14310	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FDV78_RS14315	COG1722	exodeoxyribonuclease VII activity
FDV78_RS14320	COG0142	geranyltranstransferase activity
FDV78_RS14325	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FDV78_RS14330	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FDV78_RS14335	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FDV78_RS14340	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FDV78_RS14360	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FDV78_RS14360	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FDV78_RS14365	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FDV78_RS14370	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FDV78_RS14375	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FDV78_RS14390	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
FDV78_RS14395	COG2252	PERMEase
FDV78_RS14400	COG2195	Cleaves the N-terminal amino acid of tripeptides
FDV78_RS14425	COG0047	phosphoribosylformylglycinamidine synthase activity
FDV78_RS14425	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FDV78_RS14430	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FDV78_RS14440	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
FDV78_RS14470	COG0484	heat shock protein binding
FDV78_RS14475	COG0443	Heat shock 70 kDa protein
FDV78_RS14485	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FDV78_RS14490	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FDV78_RS14500	COG0497	DNA recombination
FDV78_RS14505	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FDV78_RS14510	COG2914	Belongs to the UPF0125 (RnfH) family
FDV78_RS14515	COG2867	negative regulation of translational initiation
FDV78_RS14520	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FDV78_RS14530	COG0582	viral genome integration into host DNA
FDV78_RS14640	COG5001	Diguanylate cyclase
FDV78_RS14640	COG3300	MHYT domain
FDV78_RS14670	COG1396	sequence-specific DNA binding
FDV78_RS14685	COG0583	DNA-binding transcription factor activity
FDV78_RS14690	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FDV78_RS14690	COG3153	acetyltransferase
FDV78_RS14710	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FDV78_RS14715	COG2873	o-acetylhomoserine
FDV78_RS14745	COG1115	amino acid carrier protein
FDV78_RS14755	COG1584	GPR1 FUN34 yaaH family protein
FDV78_RS14765	COG1757	Na H antiporter
FDV78_RS14770	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FDV78_RS14770	COG0519	Catalyzes the synthesis of GMP from XMP
FDV78_RS14775	COG0517	IMP dehydrogenase activity
FDV78_RS14775	COG0516	GMP reductase activity
FDV78_RS14780	COG1570	exodeoxyribonuclease VII activity
FDV78_RS14795	COG1160	GTP binding
FDV78_RS14800	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FDV78_RS14805	COG2976	Protein conserved in bacteria
FDV78_RS14810	COG0124	histidyl-tRNA synthetase
FDV78_RS14815	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FDV78_RS14825	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FDV78_RS14830	COG0105	UTP biosynthetic process
FDV78_RS14835	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FDV78_RS14840	COG2975	iron-sulfur cluster assembly
FDV78_RS14845	COG0633	Ferredoxin
FDV78_RS14850	COG0443	Heat shock 70 kDa protein
FDV78_RS14855	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FDV78_RS14865	COG0822	iron-sulfur transferase activity
FDV78_RS14870	COG1104	cysteine desulfurase activity
FDV78_RS14885	COG0483	inositol monophosphate 1-phosphatase activity
FDV78_RS14890	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FDV78_RS14895	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FDV78_RS14900	COG1862	Preprotein translocase
FDV78_RS14905	COG0343	queuine tRNA-ribosyltransferase activity
FDV78_RS14910	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FDV78_RS14920	COG0517	IMP dehydrogenase activity
FDV78_RS14930	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FDV78_RS14935	COG0583	DNA-binding transcription factor activity
FDV78_RS14940	COG0450	alkyl hydroperoxide reductase
FDV78_RS14945	COG3142	Participates in the control of copper homeostasis
FDV78_RS14955	COG0704	Plays a role in the regulation of phosphate uptake
FDV78_RS14960	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FDV78_RS14965	COG0581	inorganic phosphate transmembrane transporter activity
FDV78_RS14975	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FDV78_RS14980	COG0248	Ppx GppA phosphatase
FDV78_RS14990	COG5002	protein histidine kinase activity
FDV78_RS14995	COG0745	RESPONSE REGULATOR receiver
FDV78_RS15000	COG2974	May be involved in recombination
FDV78_RS15010	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FDV78_RS15070	COG0542	response to heat
FDV78_RS15080	COG0564	pseudouridine synthase activity
FDV78_RS15085	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FDV78_RS15090	COG0741	lytic transglycosylase activity
FDV78_RS15095	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FDV78_RS15100	COG1605	Chorismate mutase
FDV78_RS15100	COG0077	Prephenate dehydratase
FDV78_RS15105	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
FDV78_RS15110	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
FDV78_RS15120	COG0488	(ABC) transporter
FDV78_RS15130	COG0739	heme binding
FDV78_RS15135	COG0287	Prephenate dehydrogenase
FDV78_RS15135	COG1605	Chorismate mutase
FDV78_RS15140	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FDV78_RS15145	COG1472	Belongs to the glycosyl hydrolase 3 family
FDV78_RS15150	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FDV78_RS15155	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FDV78_RS15170	COG1966	Carbon starvation protein
FDV78_RS15175	COG3275	phosphorelay sensor kinase activity
FDV78_RS15180	COG3279	Response regulator of the LytR AlgR family
FDV78_RS15185	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FDV78_RS15190	COG1047	Peptidyl-prolyl cis-trans
FDV78_RS15195	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FDV78_RS15200	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FDV78_RS15205	COG0196	riboflavin kinase activity
FDV78_RS15210	COG0728	peptidoglycan biosynthetic process
FDV78_RS15215	COG0268	Binds directly to 16S ribosomal RNA
FDV78_RS15220	COG0640	Transcriptional regulator
FDV78_RS15225	COG0583	DNA-binding transcription factor activity
FDV78_RS15230	COG1283	sodium-dependent phosphate transmembrane transporter activity
FDV78_RS15240	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FDV78_RS15245	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FDV78_RS15250	COG0730	response to heat
FDV78_RS15255	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
FDV78_RS15260	COG0494	nUDIX hydrolase
FDV78_RS15265	COG3066	DNA modification
FDV78_RS15275	COG0667	Aldo Keto reductase
FDV78_RS15290	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FDV78_RS15300	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FDV78_RS15305	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FDV78_RS15310	COG4974	Belongs to the 'phage' integrase family
FDV78_RS15315	COG0716	FMN binding
FDV78_RS15325	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FDV78_RS15330	COG0513	Belongs to the DEAD box helicase family
FDV78_RS15335	COG3022	response to hydroperoxide
FDV78_RS15340	COG1115	amino acid carrier protein
FDV78_RS15355	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FDV78_RS15360	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
FDV78_RS15365	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
FDV78_RS15370	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FDV78_RS15375	COG0083	homoserine kinase activity
FDV78_RS15390	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FDV78_RS15400	COG0745	RESPONSE REGULATOR receiver
FDV78_RS15410	COG0784	Response regulator, receiver
FDV78_RS15410	COG2198	Histidine kinase
FDV78_RS15410	COG5002	protein histidine kinase activity
FDV78_RS15415	COG2203	Gaf domain
FDV78_RS15415	COG3706	GGDEF domain
FDV78_RS15415	COG4251	negative regulation of phosphorylation
FDV78_RS15415	COG5001	Diguanylate cyclase
FDV78_RS15420	COG1242	4 iron, 4 sulfur cluster binding
FDV78_RS15425	COG0069	glutamate synthase activity
FDV78_RS15425	COG0070	glutamate synthase
FDV78_RS15425	COG0067	glutamate synthase
FDV78_RS15435	COG0069	glutamate synthase activity
FDV78_RS15435	COG0067	glutamate synthase
FDV78_RS15435	COG0070	glutamate synthase
FDV78_RS15440	COG0493	'glutamate synthase
FDV78_RS15450	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FDV78_RS15460	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FDV78_RS15465	COG2860	membrane
FDV78_RS15470	COG0583	DNA-binding transcription factor activity
FDV78_RS15475	COG0730	response to heat
FDV78_RS15490	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FDV78_RS15495	COG0505	Belongs to the CarA family
FDV78_RS15500	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FDV78_RS15505	COG0494	nUDIX hydrolase
FDV78_RS15510	COG0653	protein targeting
FDV78_RS15520	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
FDV78_RS15525	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FDV78_RS15530	COG0849	cell division
FDV78_RS15535	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FDV78_RS15540	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FDV78_RS15545	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FDV78_RS15550	COG0772	Belongs to the SEDS family
FDV78_RS15555	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FDV78_RS15560	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FDV78_RS15565	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FDV78_RS15570	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FDV78_RS15575	COG0768	penicillin binding
FDV78_RS15580	COG3116	cell division
FDV78_RS15585	COG0275	rRNA processing
FDV78_RS15595	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FDV78_RS15605	COG0792	nuclease activity
FDV78_RS15610	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FDV78_RS15615	COG2823	Periplasmic or secreted lipoprotein
FDV78_RS15620	COG2969	positive regulation of protein catabolic process
FDV78_RS15625	COG0625	glutathione transferase activity
FDV78_RS15630	COG2857	Cytochrome c1
FDV78_RS15635	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FDV78_RS15640	COG0723	plastoquinol--plastocyanin reductase activity
FDV78_RS15645	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FDV78_RS15650	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FDV78_RS15655	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FDV78_RS15660	COG3105	Protein conserved in bacteria
FDV78_RS15670	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FDV78_RS15675	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FDV78_RS15685	COG3150	esterase
FDV78_RS15695	COG3151	Protein conserved in bacteria
FDV78_RS15700	COG0494	nUDIX hydrolase
FDV78_RS15705	COG1538	Outer membrane efflux protein
FDV78_RS15710	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FDV78_RS15710	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FDV78_RS15715	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FDV78_RS15730	COG3025	triphosphatase activity
FDV78_RS15735	COG1392	Phosphate transport regulator
FDV78_RS15740	COG0306	phosphate transporter
FDV78_RS15745	COG4991	sh3 domain protein
FDV78_RS15755	COG3267	Type II secretory pathway component ExeA
FDV78_RS15755	COG3409	Peptidoglycan-binding domain 1 protein
FDV78_RS15760	COG0617	tRNA 3'-terminal CCA addition
FDV78_RS15765	COG1968	undecaprenyl-diphosphatase activity
FDV78_RS15770	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FDV78_RS15775	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FDV78_RS15780	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FDV78_RS15785	COG0596	Alpha beta hydrolase
FDV78_RS15790	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FDV78_RS15795	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FDV78_RS15800	COG1610	YqeY-like protein
FDV78_RS15805	COG0358	DNA primase activity
FDV78_RS15865	COG0582	viral genome integration into host DNA
FDV78_RS15870	COG1464	Belongs to the NlpA lipoprotein family
FDV78_RS15900	COG2213	PTS system mannitol-specific
FDV78_RS15900	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FDV78_RS15905	COG0246	Mannitol dehydrogenase
FDV78_RS15910	COG3722	fumarate hydratase activity
FDV78_RS15915	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FDV78_RS15920	COG5002	protein histidine kinase activity
FDV78_RS15935	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FDV78_RS15940	COG1349	DNA-binding transcription factor activity
FDV78_RS15945	COG0469	pyruvate kinase activity
FDV78_RS15955	COG3706	GGDEF domain
FDV78_RS15960	COG0440	acetolactate synthase activity
FDV78_RS15965	COG0028	Belongs to the TPP enzyme family
FDV78_RS15970	COG1022	Amp-dependent synthetase and ligase
FDV78_RS15975	COG0583	DNA-binding transcription factor activity
FDV78_RS15995	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FDV78_RS16000	COG0473	3-isopropylmalate dehydrogenase activity
FDV78_RS16005	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FDV78_RS16010	COG0066	3-isopropylmalate dehydratase activity
FDV78_RS16020	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FDV78_RS16025	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FDV78_RS16030	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FDV78_RS16035	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FDV78_RS16040	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FDV78_RS16045	COG2967	ApaG domain
FDV78_RS16050	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FDV78_RS16065	COG2966	Psort location CytoplasmicMembrane, score
FDV78_RS16070	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FDV78_RS16080	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FDV78_RS16085	COG0142	geranyltranstransferase activity
FDV78_RS16095	COG0039	L-malate dehydrogenase activity
FDV78_RS16105	COG2358	TRAP transporter, solute receptor (TAXI family
FDV78_RS16120	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FDV78_RS16125	COG1178	ABC-type Fe3 transport system permease component
FDV78_RS16130	COG4143	(ABC) transporter
FDV78_RS16135	COG0163	prenyltransferase activity
FDV78_RS16140	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FDV78_RS16145	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
FDV78_RS16150	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FDV78_RS16160	COG2105	PFAM AIG2 family protein
FDV78_RS16170	COG0729	surface antigen
FDV78_RS16175	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FDV78_RS16185	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
FDV78_RS16200	COG4181	ATPase activity
FDV78_RS16220	COG0529	Catalyzes the synthesis of activated sulfate
FDV78_RS16225	COG3273	potassium ion transport
FDV78_RS16225	COG0471	metal ion transport
FDV78_RS16230	COG2895	sulfate adenylyltransferase (ATP) activity
FDV78_RS16235	COG0175	sulfate reduction
FDV78_RS16240	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FDV78_RS16240	COG1648	precorrin-2 dehydrogenase activity
FDV78_RS16245	COG0737	Belongs to the 5'-nucleotidase family
FDV78_RS16255	COG0513	Belongs to the DEAD box helicase family
FDV78_RS16260	COG2153	protein acetylation
FDV78_RS16270	COG0545	Peptidyl-prolyl cis-trans isomerase
FDV78_RS16280	COG0203	ribosomal protein L17
FDV78_RS16285	COG0202	RNA polymerase activity
FDV78_RS16295	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FDV78_RS16300	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FDV78_RS16305	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FDV78_RS16310	COG0201	protein transport
FDV78_RS16315	COG0200	Binds to the 23S rRNA
FDV78_RS16320	COG1841	ribosomal large subunit assembly
FDV78_RS16335	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FDV78_RS16340	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FDV78_RS16345	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FDV78_RS16350	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FDV78_RS16355	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FDV78_RS16360	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FDV78_RS16365	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FDV78_RS16370	COG0255	Belongs to the universal ribosomal protein uL29 family
FDV78_RS16380	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FDV78_RS16385	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FDV78_RS16390	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FDV78_RS16395	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FDV78_RS16405	COG0088	Forms part of the polypeptide exit tunnel
FDV78_RS16410	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FDV78_RS16420	COG0254	rRNA binding
FDV78_RS16425	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FDV78_RS16430	COG1609	Transcriptional regulator
FDV78_RS16440	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FDV78_RS16445	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FDV78_RS16460	COG2003	Belongs to the UPF0758 family
FDV78_RS16490	COG1575	Belongs to the MenA family. Type 1 subfamily
FDV78_RS16495	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FDV78_RS16500	COG3074	FtsZ-dependent cytokinesis
FDV78_RS16505	COG1494	fructose-1,6-bisphosphatase
FDV78_RS16530	COG0149	triose-phosphate isomerase activity
FDV78_RS16580	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FDV78_RS16590	COG1215	transferase activity, transferring glycosyl groups
FDV78_RS16615	COG0463	Glycosyl transferase, family 2
FDV78_RS16675	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FDV78_RS16685	COG1560	Kdo2-lipid A biosynthetic process
FDV78_RS16690	COG0859	PFAM glycosyl transferase family 9
FDV78_RS16695	COG1519	Transferase
FDV78_RS16705	COG0297	glycogen (starch) synthase activity
FDV78_RS16705	COG0438	transferase activity, transferring glycosyl groups
FDV78_RS16725	COG2030	dehydratase
FDV78_RS16730	COG0110	maltose O-acetyltransferase activity
FDV78_RS16750	COG3642	lipopolysaccharide core region biosynthetic process
FDV78_RS16755	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FDV78_RS16760	COG0859	PFAM glycosyl transferase family 9
FDV78_RS16765	COG0463	Glycosyl transferase, family 2
FDV78_RS16780	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FDV78_RS16785	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FDV78_RS16800	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FDV78_RS16805	COG2003	Belongs to the UPF0758 family
FDV78_RS16815	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FDV78_RS16820	COG1309	transcriptional regulator
FDV78_RS16825	COG1560	Kdo2-lipid A biosynthetic process
FDV78_RS16830	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FDV78_RS16835	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FDV78_RS16840	COG1561	YicC-like family, N-terminal region
FDV78_RS16865	COG1404	Belongs to the peptidase S8 family
FDV78_RS16870	COG0464	growth
FDV78_RS16875	COG2003	Belongs to the UPF0758 family
FDV78_RS16930	COG0328	RNA-DNA hybrid ribonuclease activity
FDV78_RS16965	COG4608	Belongs to the ABC transporter superfamily
FDV78_RS16970	COG0444	Belongs to the ABC transporter superfamily
FDV78_RS16975	COG0747	negative chemotaxis
FDV78_RS16980	COG4239	(ABC) transporter, permease
FDV78_RS16985	COG4174	ABC transporter (Permease)
FDV78_RS17005	COG0811	peptide transport
FDV78_RS17010	COG0848	biopolymer transport protein
FDV78_RS17030	COG0194	GDP metabolic process
FDV78_RS17035	COG1758	RNA polymerase activity
FDV78_RS17040	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FDV78_RS17045	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FDV78_RS17050	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FDV78_RS17055	COG2233	PERMEase
FDV78_RS17060	COG2205	protein histidine kinase activity
FDV78_RS17065	COG0745	RESPONSE REGULATOR receiver
FDV78_RS17075	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FDV78_RS17085	COG2183	response to ionizing radiation
FDV78_RS17095	COG0596	Alpha beta hydrolase
FDV78_RS17100	COG1040	competence protein
FDV78_RS17105	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FDV78_RS17105	COG0316	Belongs to the HesB IscA family
FDV78_RS17110	COG0494	nUDIX hydrolase
FDV78_RS17115	COG1218	3'(2'),5'-bisphosphate nucleotidase
FDV78_RS17125	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
FDV78_RS17130	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
FDV78_RS17135	COG3156	type II secretion system protein K
FDV78_RS17140	COG4795	General secretion pathway protein
FDV78_RS17145	COG2165	general secretion pathway protein
FDV78_RS17150	COG2165	general secretion pathway protein
FDV78_RS17155	COG2165	general secretion pathway protein
FDV78_RS17160	COG1459	type II secretion system
FDV78_RS17165	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FDV78_RS17175	COG3031	protein transport across the cell outer membrane
FDV78_RS17180	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FDV78_RS17185	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FDV78_RS17190	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FDV78_RS17200	COG0456	acetyltransferase
FDV78_RS17205	COG1490	D-aminoacyl-tRNA deacylase activity
FDV78_RS17210	COG1295	ribonuclease BN
FDV78_RS17245	COG0641	radical SAM
FDV78_RS17260	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FDV78_RS17280	COG0456	acetyltransferase
FDV78_RS17280	COG1214	PFAM Peptidase M22, glycoprotease
FDV78_RS17290	COG3069	C4-dicarboxylate transmembrane transporter activity
FDV78_RS17295	COG1704	LemA family
FDV78_RS17300	COG0501	Belongs to the peptidase M48B family
FDV78_RS17325	COG0641	radical SAM
FDV78_RS17340	COG3111	PFAM Bacterial OB fold (BOF) protein
FDV78_RS17345	COG1597	lipid kinase activity
FDV78_RS17350	COG0583	DNA-binding transcription factor activity
FDV78_RS17355	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FDV78_RS17385	COG0714	Associated with various cellular activities
FDV78_RS17390	COG0641	radical SAM
FDV78_RS17395	COG3119	arylsulfatase activity
FDV78_RS17410	COG3119	arylsulfatase activity
FDV78_RS17415	COG3119	arylsulfatase activity
FDV78_RS17420	COG0745	RESPONSE REGULATOR receiver
FDV78_RS17435	COG2205	protein histidine kinase activity
FDV78_RS17435	COG0784	Response regulator, receiver
FDV78_RS17435	COG2198	Histidine kinase
FDV78_RS17440	COG1879	ABC-type sugar transport system periplasmic component
FDV78_RS17445	COG1803	Methylglyoxal synthase
FDV78_RS17450	COG0210	DNA helicase
FDV78_RS17455	COG1289	transmembrane transporter activity
FDV78_RS17485	COG1629	transport
FDV78_RS17485	COG4771	TonB-dependent receptor
FDV78_RS17490	COG2207	Transcriptional regulator
FDV78_RS17495	COG0789	Transcriptional regulator
FDV78_RS17500	COG4604	ABC transporter, ATP-binding protein
FDV78_RS17505	COG4605	iron ion homeostasis
FDV78_RS17510	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FDV78_RS17515	COG4607	ABC-type enterochelin transport system periplasmic component
FDV78_RS17535	COG2847	Copper chaperone PCu(A)C
FDV78_RS17540	COG0443	Heat shock 70 kDa protein
FDV78_RS17575	COG0625	glutathione transferase activity
FDV78_RS17590	COG4160	amino acid transport
FDV78_RS17595	COG4215	(ABC) transporter
FDV78_RS17600	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FDV78_RS17605	COG1126	abc transporter atp-binding protein
FDV78_RS17615	COG1902	pentaerythritol trinitrate reductase activity
FDV78_RS17630	COG0109	protoheme IX farnesyltransferase activity
FDV78_RS17635	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FDV78_RS17640	COG1845	cytochrome c oxidase, subunit III
FDV78_RS17645	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FDV78_RS17650	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FDV78_RS17655	COG1028	Short-chain dehydrogenase reductase Sdr
FDV78_RS17665	COG1024	Enoyl-CoA hydratase
FDV78_RS17670	COG1024	Enoyl-CoA hydratase
FDV78_RS17685	COG0183	Belongs to the thiolase family
FDV78_RS17695	COG1960	acyl-CoA dehydrogenase activity
FDV78_RS17700	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FDV78_RS17705	COG1024	Enoyl-CoA hydratase
FDV78_RS17715	COG5413	integral membrane protein
FDV78_RS17730	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FDV78_RS17735	COG5001	Diguanylate cyclase
FDV78_RS17740	COG0513	Belongs to the DEAD box helicase family
FDV78_RS17745	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
FDV78_RS17760	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FDV78_RS17780	COG0641	radical SAM
FDV78_RS17800	COG0840	transmembrane signaling receptor activity
FDV78_RS17805	COG1119	ATPase activity
FDV78_RS17810	COG2200	EAL domain
FDV78_RS17830	COG0513	Belongs to the DEAD box helicase family
FDV78_RS17835	COG0523	cobalamin synthesis protein
FDV78_RS17845	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
FDV78_RS17855	COG0133	tryptophan synthase activity
FDV78_RS17860	COG4628	conserved protein (DUF2132)
FDV78_RS17865	COG0513	Belongs to the DEAD box helicase family
FDV78_RS17870	COG3530	Putative quorum-sensing-regulated virulence factor
FDV78_RS17890	COG2154	pterin-4-alpha-carbinolamine dehydratase
FDV78_RS17895	COG3186	Phenylalanine-4-hydroxylase
FDV78_RS17900	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FDV78_RS17905	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FDV78_RS17945	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
FDV78_RS17950	COG1454	alcohol dehydrogenase
FDV78_RS17955	COG2133	pyrroloquinoline quinone binding
FDV78_RS17965	COG0783	Belongs to the Dps family
FDV78_RS17970	COG0840	transmembrane signaling receptor activity
FDV78_RS17980	COG0577	efflux transmembrane transporter activity
FDV78_RS17980	COG1136	(ABC) transporter
FDV78_RS18000	COG2199	diguanylate cyclase activity
FDV78_RS18010	COG3036	rescue of stalled ribosome
FDV78_RS18015	COG1278	Cold shock
FDV78_RS18045	COG0545	Peptidyl-prolyl cis-trans isomerase
FDV78_RS18050	COG0109	protoheme IX farnesyltransferase activity
FDV78_RS18055	COG1612	heme a metabolic process
FDV78_RS18080	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
FDV78_RS18090	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FDV78_RS18095	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FDV78_RS18105	COG1280	lysine exporter protein (LysE YggA)
FDV78_RS18110	COG2207	Transcriptional regulator
FDV78_RS18140	COG0697	spore germination
FDV78_RS18155	COG2814	Major facilitator Superfamily
FDV78_RS18160	COG0583	DNA-binding transcription factor activity
FDV78_RS18165	COG5001	Diguanylate cyclase
FDV78_RS18170	COG0739	heme binding
FDV78_RS18205	COG0814	amino acid
FDV78_RS18225	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FDV78_RS18230	COG1072	(Pantothenic acid kinase))
FDV78_RS18240	COG1063	alcohol dehydrogenase
FDV78_RS18245	COG2213	PTS system mannitol-specific
FDV78_RS18250	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FDV78_RS18265	COG0798	PFAM Bile acid sodium symporter
FDV78_RS18275	COG1881	PFAM PEBP family protein
FDV78_RS18285	COG2706	6-phosphogluconolactonase activity
FDV78_RS18290	COG0840	transmembrane signaling receptor activity
FDV78_RS18300	COG1131	(ABC) transporter
FDV78_RS18305	COG0842	Transport permease protein
FDV78_RS18320	COG3383	formate dehydrogenase (NAD+) activity
FDV78_RS18340	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FDV78_RS18360	COG2199	diguanylate cyclase activity
FDV78_RS18360	COG2203	Gaf domain
FDV78_RS18370	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FDV78_RS18380	COG2067	long-chain fatty acid transport protein
FDV78_RS18390	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FDV78_RS18400	COG1505	serine-type exopeptidase activity
FDV78_RS18405	COG0488	(ABC) transporter
FDV78_RS18410	COG0589	response to stress
FDV78_RS18415	COG2249	NAD(P)H dehydrogenase (quinone) activity
FDV78_RS18435	COG0366	Alpha amylase catalytic
FDV78_RS18445	COG4934	collagen metabolic process
FDV78_RS18460	COG0583	DNA-binding transcription factor activity
FDV78_RS18465	COG0783	Belongs to the Dps family
FDV78_RS18470	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FDV78_RS18510	COG2814	Major facilitator Superfamily
FDV78_RS18525	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FDV78_RS18530	COG0835	chemotaxis
FDV78_RS18530	COG0784	Response regulator, receiver
FDV78_RS18540	COG0748	coenzyme F420 binding
FDV78_RS18545	COG3721	Heme iron utilization protein
FDV78_RS18555	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
FDV78_RS18560	COG0811	peptide transport
FDV78_RS18565	COG0848	biopolymer transport protein
FDV78_RS18575	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FDV78_RS18580	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FDV78_RS18620	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FDV78_RS18625	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FDV78_RS18630	COG0633	Ferredoxin
FDV78_RS18630	COG3217	Mosc domain protein beta barrel domain protein
FDV78_RS18630	COG0633	Ferredoxin
FDV78_RS18630	COG3217	Mosc domain protein beta barrel domain protein
FDV78_RS18635	COG0401	homolog of Blt101
FDV78_RS18640	COG0418	dihydroorotase activity
FDV78_RS18645	COG2354	Protein conserved in bacteria
FDV78_RS18675	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FDV78_RS18675	COG2207	Transcriptional regulator
FDV78_RS18680	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FDV78_RS18720	COG0513	Belongs to the DEAD box helicase family
FDV78_RS18730	COG0583	DNA-binding transcription factor activity
FDV78_RS18745	COG1902	pentaerythritol trinitrate reductase activity
FDV78_RS18750	COG1063	alcohol dehydrogenase
FDV78_RS18760	COG1028	Short-chain dehydrogenase reductase Sdr
FDV78_RS18770	COG3122	Protein conserved in bacteria
FDV78_RS18785	COG0583	DNA-binding transcription factor activity
FDV78_RS18795	COG0252	asparaginase activity
FDV78_RS18800	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FDV78_RS18805	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FDV78_RS18805	COG0574	Belongs to the PEP-utilizing enzyme family
FDV78_RS18825	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FDV78_RS18845	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FDV78_RS18865	COG3706	GGDEF domain
FDV78_RS18885	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FDV78_RS18915	COG3842	ATPase activity
FDV78_RS18940	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FDV78_RS18975	COG0583	DNA-binding transcription factor activity
FDV78_RS18985	COG4948	Mandelate Racemase Muconate Lactonizing
FDV78_RS19015	COG1342	Belongs to the UPF0251 family
FDV78_RS19020	COG3015	lipoprotein NlpE involved in copper resistance
FDV78_RS19025	COG3713	MltA-interacting MipA family protein
FDV78_RS19040	COG0583	DNA-binding transcription factor activity
FDV78_RS19060	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FDV78_RS19070	COG1335	isochorismatase
FDV78_RS19080	COG0753	catalase activity
FDV78_RS19090	COG1349	DNA-binding transcription factor activity
FDV78_RS19095	COG0346	lactoylglutathione lyase activity
FDV78_RS19110	COG0583	DNA-binding transcription factor activity
FDV78_RS19120	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FDV78_RS19130	COG0737	Belongs to the 5'-nucleotidase family
FDV78_RS19140	COG1309	transcriptional regulator
FDV78_RS19160	COG1280	lysine exporter protein (LysE YggA)
FDV78_RS19175	COG0459	protein refolding
FDV78_RS19180	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FDV78_RS19185	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FDV78_RS19210	COG1304	FMN binding
FDV78_RS19230	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FDV78_RS19235	COG1256	bacterial-type flagellum assembly
FDV78_RS19235	COG4786	Flagellar basal body rod
FDV78_RS19245	COG1706	bacterial-type flagellum-dependent cell motility
FDV78_RS19250	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FDV78_RS19255	COG4786	Flagellar basal body rod
FDV78_RS19260	COG4787	bacterial-type flagellum-dependent cell motility
FDV78_RS19265	COG1749	Flagellar hook protein flgE
FDV78_RS19270	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FDV78_RS19275	COG1558	bacterial-type flagellum-dependent cell motility
FDV78_RS19280	COG1815	bacterial-type flagellum-dependent cell motility
FDV78_RS19300	COG0741	lytic transglycosylase activity
FDV78_RS19305	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FDV78_RS19325	COG1760	l-serine dehydratase
FDV78_RS19330	COG3104	oligopeptide transport
FDV78_RS19350	COG0583	DNA-binding transcription factor activity
FDV78_RS19360	COG2866	Carboxypeptidase
FDV78_RS19365	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FDV78_RS19370	COG2990	Protein conserved in bacteria
FDV78_RS19395	COG3842	ATPase activity
FDV78_RS19405	COG1840	ABC-type Fe3 transport system, periplasmic component
FDV78_RS19420	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FDV78_RS19425	COG1609	Transcriptional regulator
FDV78_RS19455	COG3240	lipase activity
FDV78_RS19465	COG1136	(ABC) transporter
FDV78_RS19465	COG0577	efflux transmembrane transporter activity
FDV78_RS19470	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FDV78_RS19475	COG2067	long-chain fatty acid transport protein
FDV78_RS19485	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
FDV78_RS19500	COG1011	Hydrolase
FDV78_RS19540	COG0110	maltose O-acetyltransferase activity
FDV78_RS19545	COG1765	OsmC-like protein
FDV78_RS19550	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FDV78_RS19550	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FDV78_RS19565	COG3046	protein related to deoxyribodipyrimidine photolyase
FDV78_RS19570	COG0415	Belongs to the DNA photolyase family
FDV78_RS19575	COG3706	GGDEF domain
FDV78_RS19590	COG0840	transmembrane signaling receptor activity
FDV78_RS19595	COG3706	GGDEF domain
FDV78_RS19610	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FDV78_RS19625	COG3033	Beta-eliminating lyase
FDV78_RS19635	COG0579	oxidoreductase
FDV78_RS19655	COG3706	GGDEF domain
FDV78_RS19700	COG0583	DNA-binding transcription factor activity
FDV78_RS19705	COG0189	ligase activity
FDV78_RS19710	COG4067	protein conserved in archaea
FDV78_RS19710	COG0189	ligase activity
FDV78_RS19720	COG1166	arginine decarboxylase activity
FDV78_RS19725	COG0010	Belongs to the arginase family
FDV78_RS19730	COG2814	Major facilitator Superfamily
FDV78_RS19735	COG1770	oligopeptidase
FDV78_RS19750	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FDV78_RS19755	COG1121	(ABC) transporter
FDV78_RS19760	COG0803	Belongs to the bacterial solute-binding protein 9 family
FDV78_RS19800	COG0848	biopolymer transport protein
FDV78_RS19805	COG0811	peptide transport
FDV78_RS19810	COG0811	peptide transport
FDV78_RS19830	COG0745	RESPONSE REGULATOR receiver
FDV78_RS19835	COG0039	L-malate dehydrogenase activity
FDV78_RS19840	COG0584	glycerophosphoryl diester phosphodiesterase
FDV78_RS19850	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FDV78_RS19905	COG1901	pseudouridine methyltransferase
FDV78_RS19910	COG0312	modulator of DNA gyrase
FDV78_RS19915	COG0312	modulator of DNA gyrase
FDV78_RS19920	COG0351	phosphomethylpyrimidine kinase
FDV78_RS19925	COG1116	anion transmembrane transporter activity
FDV78_RS19930	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FDV78_RS19935	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FDV78_RS19940	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FDV78_RS19945	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
FDV78_RS19950	COG0352	thiamine-phosphate diphosphorylase activity
FDV78_RS19960	COG0243	molybdopterin cofactor binding
FDV78_RS19965	COG3005	denitrification pathway
FDV78_RS19975	COG1028	Short-chain dehydrogenase reductase Sdr
FDV78_RS19990	COG0456	acetyltransferase
FDV78_RS20010	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FDV78_RS20015	COG1929	Belongs to the glycerate kinase type-1 family
FDV78_RS20020	COG2610	gluconate transmembrane transporter activity
FDV78_RS20025	COG3835	regulator
FDV78_RS20050	COG0546	phosphoglycolate phosphatase activity
FDV78_RS20065	COG0583	DNA-binding transcription factor activity
FDV78_RS20080	COG0641	radical SAM
FDV78_RS20085	COG0583	DNA-binding transcription factor activity
FDV78_RS20105	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
FDV78_RS20110	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
FDV78_RS20110	COG3408	Glycogen debranching enzyme
FDV78_RS20140	COG3047	cAMP biosynthetic process
FDV78_RS20145	COG1357	PFAM Pentapeptide repeats (8 copies)
FDV78_RS20175	COG2375	cellular response to nickel ion
FDV78_RS20180	COG0823	Involved in the tonB-independent uptake of proteins
FDV78_RS20185	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FDV78_RS20205	COG0800	Aldolase
FDV78_RS20210	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FDV78_RS20225	COG1917	Cupin 2, conserved barrel domain protein
FDV78_RS20235	COG1028	Short-chain dehydrogenase reductase Sdr
FDV78_RS20240	COG1414	Transcriptional regulator
FDV78_RS20255	COG0583	DNA-binding transcription factor activity
FDV78_RS20260	COG2162	N-hydroxyarylamine O-acetyltransferase activity
FDV78_RS20265	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FDV78_RS20280	COG2199	diguanylate cyclase activity
FDV78_RS20290	COG0561	phosphatase activity
FDV78_RS20295	COG0583	DNA-binding transcription factor activity
FDV78_RS20310	COG0564	pseudouridine synthase activity
FDV78_RS20315	COG0534	Mate efflux family protein
FDV78_RS20320	COG5001	Diguanylate cyclase
FDV78_RS20330	COG3123	guanosine phosphorylase activity
FDV78_RS20370	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FDV78_RS20380	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FDV78_RS20385	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FDV78_RS20395	COG2259	Doxx family
FDV78_RS20400	COG1741	Belongs to the pirin family
FDV78_RS20420	COG0363	glucosamine-6-phosphate deaminase activity
FDV78_RS20430	COG0786	glutamate:sodium symporter activity
FDV78_RS20435	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FDV78_RS20440	COG1131	(ABC) transporter
FDV78_RS20450	COG0786	glutamate:sodium symporter activity
FDV78_RS20475	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FDV78_RS20485	COG3279	Response regulator of the LytR AlgR family
FDV78_RS20490	COG3275	phosphorelay sensor kinase activity
FDV78_RS20510	COG1136	(ABC) transporter
FDV78_RS20520	COG0772	Belongs to the SEDS family
FDV78_RS20525	COG0217	transcriptional regulatory protein
FDV78_RS20545	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FDV78_RS20545	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
FDV78_RS20555	COG0444	Belongs to the ABC transporter superfamily
FDV78_RS20560	COG4608	Belongs to the ABC transporter superfamily
FDV78_RS20585	COG1444	tRNA N-acetyltransferase activity
FDV78_RS20605	COG3340	Belongs to the peptidase S51 family
FDV78_RS20610	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FDV78_RS20615	COG1263	PTS System
FDV78_RS20615	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FDV78_RS20620	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FDV78_RS20635	COG4166	transmembrane transport
FDV78_RS20680	COG0259	pyridoxamine-phosphate oxidase activity
FDV78_RS20705	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FDV78_RS20750	COG1132	(ABC) transporter
FDV78_RS20760	COG2207	Transcriptional regulator
FDV78_RS20780	COG0800	Aldolase
FDV78_RS20785	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FDV78_RS20790	COG1904	glucuronate isomerase
FDV78_RS20795	COG0246	Mannitol dehydrogenase
FDV78_RS20805	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FDV78_RS20815	COG2186	Transcriptional regulator
FDV78_RS20825	COG0513	Belongs to the DEAD box helicase family
FDV78_RS20830	COG2258	MOSC domain
FDV78_RS20845	COG1486	melibiose metabolic process
FDV78_RS20850	COG0583	DNA-binding transcription factor activity
FDV78_RS20865	COG1595	DNA-templated transcription, initiation
FDV78_RS20890	COG3634	alkyl hydroperoxide reductase activity
FDV78_RS20900	COG1846	Transcriptional regulator
FDV78_RS20905	COG1764	response to oxidative stress
FDV78_RS20930	COG2160	L-arabinose isomerase activity
FDV78_RS20940	COG1069	ribulokinase activity
FDV78_RS20945	COG1879	ABC-type sugar transport system periplasmic component
FDV78_RS20950	COG1129	ABC transporter
FDV78_RS20955	COG1172	Belongs to the binding-protein-dependent transport system permease family
FDV78_RS20975	COG0745	RESPONSE REGULATOR receiver
FDV78_RS20985	COG1653	transport
FDV78_RS20990	COG0019	diaminopimelate decarboxylase activity
FDV78_RS20995	COG4264	IucA IucC family
FDV78_RS21020	COG4772	TonB-dependent receptor
FDV78_RS21025	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FDV78_RS21030	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FDV78_RS21035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FDV78_RS21040	COG1120	ATPase activity
FDV78_RS21045	COG0840	transmembrane signaling receptor activity
FDV78_RS21050	COG0612	Peptidase, M16
FDV78_RS21060	COG0739	heme binding
FDV78_RS21070	COG2814	Major facilitator Superfamily
FDV78_RS21085	COG4580	involved in the transport of maltose and maltodextrins
FDV78_RS21105	COG2356	endonuclease I
FDV78_RS21125	COG1982	Orn Lys Arg decarboxylase major
FDV78_RS21130	COG0531	amino acid
FDV78_RS21140	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
FDV78_RS21150	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
FDV78_RS21155	COG1162	GTPase activity
FDV78_RS21160	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FDV78_RS21160	COG1263	PTS System
FDV78_RS21170	COG1999	signal sequence binding
FDV78_RS21185	COG2909	trisaccharide binding
FDV78_RS21190	COG0058	SHG alpha-glucan phosphorylase activity
FDV78_RS21195	COG1640	4-alpha-glucanotransferase
FDV78_RS21200	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FDV78_RS21205	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FDV78_RS21210	COG0366	Alpha amylase catalytic
FDV78_RS21220	COG3366	ferrous iron transmembrane transporter activity
FDV78_RS21225	COG0700	Nucleoside recognition
FDV78_RS21230	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FDV78_RS21235	COG3339	Conserved Protein
FDV78_RS21240	COG1301	dicarboxylic acid transport
FDV78_RS21250	COG0583	DNA-binding transcription factor activity
FDV78_RS21265	COG0489	protein tyrosine kinase activity
FDV78_RS21265	COG3206	protein involved in exopolysaccharide biosynthesis
FDV78_RS21285	COG2095	MarC family integral membrane protein
FDV78_RS21290	COG4667	esterase of the alpha-beta hydrolase superfamily
FDV78_RS21295	COG3397	chitin binding
FDV78_RS21315	COG1686	Belongs to the peptidase S11 family
FDV78_RS21340	COG0583	DNA-binding transcription factor activity
FDV78_RS21345	COG4628	conserved protein (DUF2132)
FDV78_RS21355	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FDV78_RS21365	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
FDV78_RS21370	COG0628	permease
FDV78_RS21410	COG2814	Major facilitator Superfamily
FDV78_RS21430	COG0454	-acetyltransferase
FDV78_RS21440	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FDV78_RS21445	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FDV78_RS21450	COG1882	Formate acetyltransferase
FDV78_RS21480	COG1360	Flagellar Motor Protein
FDV78_RS21485	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FDV78_RS21490	COG1191	sigma factor activity
FDV78_RS21495	COG1580	Controls the rotational direction of flagella during chemotaxis
FDV78_RS21510	COG1516	flagellar protein fliS
FDV78_RS21515	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FDV78_RS21525	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FDV78_RS21540	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FDV78_RS21550	COG1987	bacterial-type flagellum assembly
FDV78_RS21630	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FDV78_RS21650	COG0346	lactoylglutathione lyase activity
FDV78_RS21675	COG0745	RESPONSE REGULATOR receiver
FDV78_RS21695	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FDV78_RS21705	COG0156	8-amino-7-oxononanoate synthase activity
FDV78_RS21710	COG1063	alcohol dehydrogenase
FDV78_RS21745	COG0668	transmembrane transport
FDV78_RS21755	COG1304	FMN binding
FDV78_RS21760	COG1620	l-lactate permease
FDV78_RS21765	COG0583	DNA-binding transcription factor activity
FDV78_RS21770	COG1505	serine-type exopeptidase activity
FDV78_RS21775	COG4172	Belongs to the ABC transporter superfamily
FDV78_RS21785	COG1067	ATP-dependent peptidase activity
FDV78_RS21810	COG1247	-acetyltransferase
FDV78_RS21815	COG0437	4 iron, 4 sulfur cluster binding
FDV78_RS21820	COG0348	domain, Protein
FDV78_RS21835	COG1122	ATPase activity
FDV78_RS21840	COG4720	Psort location CytoplasmicMembrane, score
FDV78_RS21845	COG1566	PFAM secretion protein HlyD family protein
FDV78_RS21855	COG3706	GGDEF domain
FDV78_RS21870	COG0813	purine-nucleoside phosphorylase activity
FDV78_RS21875	COG3272	Protein of unknown function (DUF1722)
FDV78_RS21880	COG0789	Transcriptional regulator
FDV78_RS21885	COG0415	Belongs to the DNA photolyase family
FDV78_RS21890	COG1376	ErfK ybiS ycfS ynhG family protein
FDV78_RS21890	COG1388	LysM domain
FDV78_RS21900	COG0513	Belongs to the DEAD box helicase family
FDV78_RS21905	COG1770	oligopeptidase
FDV78_RS21910	COG4771	TonB-dependent receptor
FDV78_RS21940	COG0573	inorganic phosphate transmembrane transporter activity
FDV78_RS21945	COG0581	inorganic phosphate transmembrane transporter activity
FDV78_RS21950	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FDV78_RS21965	COG2304	oxidoreductase activity
FDV78_RS21985	COG0714	Associated with various cellular activities
FDV78_RS21990	COG0840	transmembrane signaling receptor activity
FDV78_RS22050	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FDV78_RS22055	COG1120	ATPase activity
FDV78_RS22060	COG4774	siderophore transport
FDV78_RS22065	COG1132	(ABC) transporter
FDV78_RS22070	COG2205	protein histidine kinase activity
FDV78_RS22070	COG2205	protein histidine kinase activity
FDV78_RS22080	COG0569	domain protein
FDV78_RS22085	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FDV78_RS22090	COG3300	MHYT domain
FDV78_RS22090	COG5001	Diguanylate cyclase
FDV78_RS22095	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
FDV78_RS22100	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FDV78_RS22115	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FDV78_RS22115	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FDV78_RS22115	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FDV78_RS22120	COG2207	Transcriptional regulator
FDV78_RS22130	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FDV78_RS22135	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FDV78_RS22140	COG2084	Dehydrogenase
FDV78_RS22145	COG0753	catalase activity
FDV78_RS22155	COG2130	NADP-dependent
FDV78_RS22160	COG1309	transcriptional regulator
FDV78_RS22195	COG0438	transferase activity, transferring glycosyl groups
FDV78_RS22225	COG3842	ATPase activity
FDV78_RS22235	COG1175	transmembrane transport
FDV78_RS22240	COG3833	ABC-type maltose transport systems, permease component
FDV78_RS22260	COG3746	phosphate-selective porin O and P
FDV78_RS22275	COG1028	Short-chain dehydrogenase reductase Sdr
FDV78_RS22295	COG0210	DNA helicase
FDV78_RS22300	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FDV78_RS22310	COG0625	glutathione transferase activity
FDV78_RS22315	COG1686	Belongs to the peptidase S11 family
FDV78_RS22335	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FDV78_RS22350	COG1278	Cold shock
FDV78_RS22355	COG1741	Belongs to the pirin family
FDV78_RS22360	COG4667	esterase of the alpha-beta hydrolase superfamily
FDV78_RS22395	COG0673	inositol 2-dehydrogenase activity
FDV78_RS22400	COG2194	sulfuric ester hydrolase activity
FDV78_RS22405	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FDV78_RS22415	COG2205	protein histidine kinase activity
FDV78_RS22420	COG0745	RESPONSE REGULATOR receiver
FDV78_RS22425	COG4221	oxidoreductase activity
FDV78_RS22440	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FDV78_RS22460	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FDV78_RS22470	COG2814	Major facilitator Superfamily
FDV78_RS22480	COG1418	mRNA catabolic process
FDV78_RS22490	COG0402	S-adenosylhomocysteine deaminase activity
FDV78_RS22495	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FDV78_RS22500	COG2239	Acts as a magnesium transporter
FDV78_RS22505	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FDV78_RS22520	COG0531	amino acid
FDV78_RS22525	COG1522	sequence-specific DNA binding
FDV78_RS22550	COG5002	protein histidine kinase activity
FDV78_RS22550	COG2205	protein histidine kinase activity
FDV78_RS22550	COG0784	Response regulator, receiver
FDV78_RS22555	COG0673	inositol 2-dehydrogenase activity
FDV78_RS22560	COG0534	Mate efflux family protein
FDV78_RS22565	COG2926	Belongs to the UPF0265 family
FDV78_RS22575	COG3132	Protein of unknown function, DUF480
FDV78_RS22580	COG2827	Endonuclease containing a URI domain
FDV78_RS22585	COG1879	ABC-type sugar transport system periplasmic component
FDV78_RS22590	COG2205	protein histidine kinase activity
FDV78_RS22590	COG0784	Response regulator, receiver
FDV78_RS22600	COG1566	PFAM secretion protein HlyD family protein
FDV78_RS22620	COG1522	sequence-specific DNA binding
FDV78_RS22645	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FDV78_RS22650	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FDV78_RS22670	COG0183	Belongs to the thiolase family
FDV78_RS22690	COG3005	denitrification pathway
FDV78_RS22700	COG0243	molybdopterin cofactor binding
FDV78_RS22710	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FDV78_RS22715	COG3850	Histidine kinase
FDV78_RS22720	COG2197	response regulator
FDV78_RS22735	COG2195	Cleaves the N-terminal amino acid of tripeptides
FDV78_RS22755	COG0840	transmembrane signaling receptor activity
FDV78_RS22765	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FDV78_RS22775	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FDV78_RS22780	COG2814	Major facilitator Superfamily
FDV78_RS22785	COG0840	transmembrane signaling receptor activity
FDV78_RS22790	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FDV78_RS22795	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FDV78_RS22810	COG2801	Transposase and inactivated derivatives
FDV78_RS22820	COG2897	thiosulfate sulfurtransferase activity
FDV78_RS22840	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FDV78_RS22850	COG0302	gtp cyclohydrolase
FDV78_RS22855	COG1914	H( )-stimulated, divalent metal cation uptake system
FDV78_RS22865	COG0038	chloride channel
FDV78_RS22880	COG4989	oxidoreductase activity
FDV78_RS22895	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FDV78_RS22895	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FDV78_RS22900	COG0516	GMP reductase activity
FDV78_RS22910	COG2204	response regulator
FDV78_RS22915	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
FDV78_RS22955	COG0515	serine threonine protein kinase
FDV78_RS22980	COG1196	nuclear chromosome segregation
FDV78_RS22990	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FDV78_RS23055	COG3474	cytochrome
FDV78_RS23065	COG0789	Transcriptional regulator
FDV78_RS23070	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FDV78_RS23075	COG0384	phenazine biosynthesis protein PhzF
FDV78_RS23085	COG1294	oxidase, subunit
FDV78_RS23090	COG1271	oxidase subunit
FDV78_RS23095	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FDV78_RS23100	COG0110	maltose O-acetyltransferase activity
FDV78_RS23105	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FDV78_RS23105	COG3264	Mechanosensitive ion channel
FDV78_RS23120	COG2205	protein histidine kinase activity
FDV78_RS23120	COG3437	response regulator, receiver
FDV78_RS23120	COG3850	Histidine kinase
FDV78_RS23120	COG4999	Histidine kinase
FDV78_RS23135	COG1024	Enoyl-CoA hydratase
FDV78_RS23140	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FDV78_RS23145	COG1960	acyl-CoA dehydrogenase activity
FDV78_RS23155	COG0183	Belongs to the thiolase family
FDV78_RS23165	COG1960	acyl-CoA dehydrogenase activity
FDV78_RS23170	COG1024	Enoyl-CoA hydratase
FDV78_RS23185	COG1028	Short-chain dehydrogenase reductase Sdr
FDV78_RS23190	COG3706	GGDEF domain
FDV78_RS23195	COG1309	transcriptional regulator
FDV78_RS23200	COG1012	belongs to the aldehyde dehydrogenase family
FDV78_RS23215	COG4176	ABC-type proline glycine betaine transport system permease component
FDV78_RS23220	COG0517	IMP dehydrogenase activity
FDV78_RS23220	COG4175	Glycine betaine
FDV78_RS23235	COG0330	HflC and HflK could
FDV78_RS23245	COG5001	Diguanylate cyclase
FDV78_RS23245	COG3300	MHYT domain
FDV78_RS23255	COG0784	Response regulator, receiver
FDV78_RS23255	COG2205	protein histidine kinase activity
FDV78_RS23310	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FDV78_RS23315	COG5001	Diguanylate cyclase
FDV78_RS23320	COG1869	D-ribose catabolic process
FDV78_RS23325	COG1129	ABC transporter
FDV78_RS23330	COG1172	Belongs to the binding-protein-dependent transport system permease family
FDV78_RS23335	COG1879	ABC-type sugar transport system periplasmic component
FDV78_RS23340	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FDV78_RS23345	COG1609	Transcriptional regulator
FDV78_RS23355	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
FDV78_RS23375	COG0745	RESPONSE REGULATOR receiver
FDV78_RS23390	COG1785	Belongs to the alkaline phosphatase family
FDV78_RS23415	COG0814	amino acid
FDV78_RS23425	COG0243	molybdopterin cofactor binding
FDV78_RS23430	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FDV78_RS23430	COG1648	precorrin-2 dehydrogenase activity
FDV78_RS23445	COG3707	response regulator
FDV78_RS23450	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FDV78_RS23455	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FDV78_RS23460	COG1116	anion transmembrane transporter activity
FDV78_RS23465	COG2146	nitrite reductase [NAD(P)H] activity
FDV78_RS23465	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FDV78_RS23525	COG0515	serine threonine protein kinase
FDV78_RS23525	COG2815	serine threonine protein kinase
FDV78_RS23560	COG0631	protein serine/threonine phosphatase activity
FDV78_RS23615	COG3501	Rhs element vgr protein
FDV78_RS23630	COG0420	3'-5' exonuclease activity
FDV78_RS23635	COG0419	ATPase involved in DNA repair
FDV78_RS23655	COG3040	lipid binding
FDV78_RS23665	COG2814	Major facilitator Superfamily
FDV78_RS23675	COG1288	antiporter activity
FDV78_RS23685	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
FDV78_RS23700	COG2425	protein containing a von Willebrand factor type A (vWA) domain
FDV78_RS23715	COG0583	DNA-binding transcription factor activity
FDV78_RS23720	COG0277	FAD linked oxidase domain protein
FDV78_RS23735	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FDV78_RS23775	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FDV78_RS23775	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FDV78_RS23810	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FDV78_RS23815	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FDV78_RS23825	COG2116	formate transmembrane transporter activity
FDV78_RS23845	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FDV78_RS23880	COG0745	RESPONSE REGULATOR receiver
FDV78_RS23880	COG2205	protein histidine kinase activity
FDV78_RS23880	COG3292	Two component regulator propeller
FDV78_RS23890	COG3118	belongs to the thioredoxin family
FDV78_RS23895	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FDV78_RS23920	COG2271	Major facilitator Superfamily
FDV78_RS23925	COG3851	Histidine kinase
FDV78_RS23930	COG2197	response regulator
FDV78_RS23940	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FDV78_RS23945	COG0583	DNA-binding transcription factor activity
FDV78_RS23950	COG0243	molybdopterin cofactor binding
FDV78_RS23980	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FDV78_RS23995	COG1328	CTP reductase activity
FDV78_RS24000	COG1328	CTP reductase activity
FDV78_RS24005	COG0602	queuosine metabolic process
FDV78_RS24070	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FDV78_RS24090	COG4974	Belongs to the 'phage' integrase family
FDV78_RS24100	COG0602	queuosine metabolic process
FDV78_RS24105	COG0534	Mate efflux family protein
FDV78_RS24120	COG4067	protein conserved in archaea
FDV78_RS24120	COG0189	ligase activity
FDV78_RS24130	COG3111	PFAM Bacterial OB fold (BOF) protein
FDV78_RS24135	COG1492	cobalamin metabolic process
FDV78_RS24140	COG0725	ABC transporter, periplasmic molybdate-binding protein
FDV78_RS24145	COG4149	molybdate abc transporter
FDV78_RS24150	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FDV78_RS24160	COG3706	GGDEF domain
FDV78_RS24160	COG2203	Gaf domain
FDV78_RS24160	COG5001	Diguanylate cyclase
FDV78_RS24160	COG4251	negative regulation of phosphorylation
FDV78_RS24185	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FDV78_RS24190	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FDV78_RS24215	COG3140	Belongs to the UPF0181 family
FDV78_RS24225	COG0589	response to stress
FDV78_RS24235	COG0583	DNA-binding transcription factor activity
FDV78_RS24250	COG0023	Translation Initiation Factor
FDV78_RS24260	COG1181	Belongs to the D-alanine--D-alanine ligase family
FDV78_RS24270	COG1042	CoA-binding domain protein
FDV78_RS24270	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FDV78_RS24270	COG0045	succinate-CoA ligase (ADP-forming) activity
FDV78_RS24275	COG0583	DNA-binding transcription factor activity
FDV78_RS24280	COG1629	transport
FDV78_RS24280	COG4771	TonB-dependent receptor
FDV78_RS24285	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FDV78_RS24290	COG5001	Diguanylate cyclase
FDV78_RS24290	COG5002	protein histidine kinase activity
FDV78_RS24290	COG3447	MASE1 domain protein
FDV78_RS24295	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FDV78_RS24300	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FDV78_RS24305	COG1984	allophanate hydrolase subunit 2
FDV78_RS24310	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FDV78_RS24310	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FDV78_RS24315	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FDV78_RS24320	COG4181	ATPase activity
FDV78_RS24330	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FDV78_RS24335	COG3300	MHYT domain
FDV78_RS24335	COG5001	Diguanylate cyclase
FDV78_RS24345	COG0484	heat shock protein binding
FDV78_RS24370	COG4533	DNA binding
FDV78_RS24380	COG2050	protein possibly involved in aromatic compounds catabolism
FDV78_RS24395	COG2067	long-chain fatty acid transport protein
FDV78_RS24400	COG2267	carboxylic ester hydrolase activity
FDV78_RS24415	COG0861	Integral membrane protein TerC family
FDV78_RS24420	COG0737	Belongs to the 5'-nucleotidase family
FDV78_RS24425	COG3593	DNA synthesis involved in DNA repair
FDV78_RS24435	COG0583	DNA-binding transcription factor activity
FDV78_RS24440	COG2116	formate transmembrane transporter activity
FDV78_RS24445	COG2353	YceI-like domain
FDV78_RS24450	COG3038	cytochrome b561
FDV78_RS24460	COG4943	cyclic-guanylate-specific phosphodiesterase activity
FDV78_RS24465	COG0513	Belongs to the DEAD box helicase family
FDV78_RS24470	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
FDV78_RS24480	COG0546	phosphoglycolate phosphatase activity
FDV78_RS24485	COG3437	response regulator, receiver
FDV78_RS24485	COG0784	Response regulator, receiver
FDV78_RS24500	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FDV78_RS24505	COG2759	Belongs to the formate--tetrahydrofolate ligase family
FDV78_RS24510	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FDV78_RS24520	COG2207	Transcriptional regulator
FDV78_RS24525	COG1979	alcohol dehydrogenase
FDV78_RS24550	COG2271	Major facilitator Superfamily
FDV78_RS24555	COG0469	pyruvate kinase activity
FDV78_RS24560	COG1126	abc transporter atp-binding protein
FDV78_RS24565	COG0765	amino acid transport
FDV78_RS24570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FDV78_RS24575	COG0765	amino acid transport
FDV78_RS24580	COG2200	EAL domain
FDV78_RS24580	COG2203	Gaf domain
FDV78_RS24580	COG2199	diguanylate cyclase activity
FDV78_RS24595	COG1609	Transcriptional regulator
FDV78_RS24600	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FDV78_RS24600	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FDV78_RS24605	COG1105	Belongs to the carbohydrate kinase PfkB family
FDV78_RS24610	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FDV78_RS24610	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FDV78_RS24610	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
FDV78_RS24650	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FDV78_RS24655	COG0509	glycine decarboxylation via glycine cleavage system
FDV78_RS24660	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FDV78_RS24660	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FDV78_RS24695	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FDV78_RS24700	COG0583	DNA-binding transcription factor activity
FDV78_RS24705	COG2176	DNA-directed DNA polymerase activity
FDV78_RS24745	COG0242	peptide deformylase activity
FDV78_RS24765	COG2239	Acts as a magnesium transporter
FDV78_RS24785	COG0346	lactoylglutathione lyase activity
FDV78_RS24790	COG1902	pentaerythritol trinitrate reductase activity
FDV78_RS24810	COG5642	Protein of unknown function (DUF2384)
FDV78_RS24815	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FDV78_RS24830	COG4565	transcriptional regulatory protein
FDV78_RS24835	COG3290	protein histidine kinase activity
FDV78_RS24840	COG0471	metal ion transport
FDV78_RS24870	COG2076	Multidrug Resistance protein
FDV78_RS24885	COG0671	phosphoesterase, PA-phosphatase related
FDV78_RS24895	COG2962	Rard protein
FDV78_RS24910	COG0835	chemotaxis
FDV78_RS24910	COG0784	Response regulator, receiver
FDV78_RS24930	COG2197	response regulator
FDV78_RS24940	COG3706	GGDEF domain
FDV78_RS24945	COG2197	response regulator
FDV78_RS24950	COG5001	Diguanylate cyclase
FDV78_RS24950	COG3300	MHYT domain
FDV78_RS24965	COG0583	DNA-binding transcription factor activity
FDV78_RS25030	COG4964	Belongs to the GSP D family
FDV78_RS25055	COG2207	Transcriptional regulator
FDV78_RS25075	COG0582	viral genome integration into host DNA
FDV78_RS25100	COG0494	nUDIX hydrolase
FDV78_RS25130	COG0737	Belongs to the 5'-nucleotidase family
FDV78_RS25135	COG1940	carbohydrate kinase activity
FDV78_RS25145	COG0477	Major facilitator Superfamily
FDV78_RS25145	COG2814	Major facilitator Superfamily
FDV78_RS25150	COG0457	Tetratricopeptide repeat
FDV78_RS25200	COG3710	Transcriptional regulator
FDV78_RS25210	COG4943	cyclic-guanylate-specific phosphodiesterase activity
FDV78_RS25215	COG0840	transmembrane signaling receptor activity
FDV78_RS25225	COG0840	transmembrane signaling receptor activity
FDV78_RS25400	COG4790	Type iii secretion
FDV78_RS25415	COG3710	Transcriptional regulator
FDV78_RS25445	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FDV78_RS25620	COG1349	DNA-binding transcription factor activity
FDV78_RS25625	COG0738	Major facilitator superfamily
FDV78_RS25630	COG2407	Converts the aldose L-fucose into the corresponding ketose L-fuculose
FDV78_RS25635	COG1070	Carbohydrate kinase
FDV78_RS25640	COG4154	Belongs to the RbsD FucU family
FDV78_RS25645	COG0235	Class ii aldolase
FDV78_RS25650	COG1454	alcohol dehydrogenase
FDV78_RS25660	COG2003	Belongs to the UPF0758 family