locus-tag	class	description
C9I78_RS00010	COG4974	Belongs to the 'phage' integrase family
C9I78_RS00020	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
C9I78_RS00030	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C9I78_RS00035	COG0250	Participates in transcription elongation, termination and antitermination
C9I78_RS00040	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
C9I78_RS00045	COG0081	regulation of translation
C9I78_RS00050	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
C9I78_RS00055	COG0222	ribosome binding
C9I78_RS00060	COG0085	RNA polymerase activity
C9I78_RS00065	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
C9I78_RS00070	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
C9I78_RS00075	COG2816	NAD+ diphosphatase activity
C9I78_RS00090	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
C9I78_RS00095	COG1573	uracil-dna glycosylase
C9I78_RS00100	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C9I78_RS00110	COG1253	flavin adenine dinucleotide binding
C9I78_RS00125	COG0151	Belongs to the GarS family
C9I78_RS00135	COG0138	bifunctional purine biosynthesis protein purh
C9I78_RS00145	COG0789	Transcriptional regulator
C9I78_RS00150	COG3710	Transcriptional regulator
C9I78_RS00160	COG0531	amino acid
C9I78_RS00165	COG1982	Orn Lys Arg decarboxylase major
C9I78_RS00230	COG3706	GGDEF domain
C9I78_RS00245	COG0488	(ABC) transporter
C9I78_RS00250	COG2814	Major facilitator Superfamily
C9I78_RS00260	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C9I78_RS00315	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
C9I78_RS00320	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C9I78_RS00325	COG2264	protein methyltransferase activity
C9I78_RS00335	COG0439	Biotin carboxylase
C9I78_RS00340	COG0511	ligase activity, forming carbon-carbon bonds
C9I78_RS00345	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
C9I78_RS00350	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C9I78_RS00365	COG2814	Major facilitator Superfamily
C9I78_RS00370	COG2205	protein histidine kinase activity
C9I78_RS00370	COG0784	Response regulator, receiver
C9I78_RS00370	COG2198	Histidine kinase
C9I78_RS00395	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C9I78_RS00405	COG3263	regulation of cellular component size
C9I78_RS00415	COG4232	protein-disulfide reductase activity
C9I78_RS00420	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
C9I78_RS00425	COG1027	Aspartate ammonia-lyase
C9I78_RS00430	COG3030	protein affecting phage T7 exclusion by the F plasmid
C9I78_RS00435	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
C9I78_RS00445	COG2205	protein histidine kinase activity
C9I78_RS00450	COG0745	RESPONSE REGULATOR receiver
C9I78_RS00460	COG3678	ATP-independent chaperone mediated protein folding
C9I78_RS00470	COG0205	6-phosphofructokinase activity
C9I78_RS00475	COG0534	Mate efflux family protein
C9I78_RS00485	COG0459	protein refolding
C9I78_RS00495	COG1285	pathogenesis
C9I78_RS00505	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C9I78_RS00515	COG1509	lysine 2,3-aminomutase activity
C9I78_RS00520	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
C9I78_RS00530	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
C9I78_RS00535	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
C9I78_RS00540	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C9I78_RS00545	COG1053	succinate dehydrogenase
C9I78_RS00555	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
C9I78_RS00575	COG4942	peptidase
C9I78_RS00580	COG1045	serine acetyltransferase
C9I78_RS00585	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
C9I78_RS00590	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
C9I78_RS00595	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C9I78_RS00600	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
C9I78_RS00615	COG0471	metal ion transport
C9I78_RS00620	COG0688	phosphatidylethanolamine metabolic process
C9I78_RS00625	COG1162	GTPase activity
C9I78_RS00630	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
C9I78_RS00700	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
C9I78_RS00705	COG0802	atpase or kinase
C9I78_RS00715	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
C9I78_RS00720	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
C9I78_RS00730	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
C9I78_RS00735	COG0330	HflC and HflK could
C9I78_RS00740	COG0330	HflC and HflK could
C9I78_RS00745	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
C9I78_RS00750	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
C9I78_RS00760	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
C9I78_RS00765	COG1017	nitric oxide dioxygenase activity
C9I78_RS00765	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C9I78_RS00770	COG1959	2 iron, 2 sulfur cluster binding
C9I78_RS00775	COG0557	exoribonuclease II activity
C9I78_RS00780	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C9I78_RS00785	COG0546	phosphoglycolate phosphatase activity
C9I78_RS00790	COG0180	Tryptophanyl-tRNA synthetase
C9I78_RS00820	COG0512	Glutamine amidotransferase of anthranilate synthase
C9I78_RS00825	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C9I78_RS00835	COG1012	belongs to the aldehyde dehydrogenase family
C9I78_RS00845	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C9I78_RS00850	COG3954	Phosphoribulokinase
C9I78_RS00855	COG3089	Belongs to the UPF0270 family
C9I78_RS00860	COG0429	hydrolase of the alpha beta-hydrolase fold
C9I78_RS00870	COG0488	(ABC) transporter
C9I78_RS00880	COG2249	NAD(P)H dehydrogenase (quinone) activity
C9I78_RS00895	COG1047	Peptidyl-prolyl cis-trans
C9I78_RS00905	COG1446	asparaginase
C9I78_RS00910	COG2900	Belongs to the SlyX family
C9I78_RS00920	COG0545	Peptidyl-prolyl cis-trans isomerase
C9I78_RS00925	COG2964	Protein conserved in bacteria
C9I78_RS00930	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
C9I78_RS00935	COG2923	Belongs to the DsrF TusC family
C9I78_RS00940	COG2168	tRNA wobble position uridine thiolation
C9I78_RS00950	COG0049	tRNA binding
C9I78_RS00955	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
C9I78_RS00960	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
C9I78_RS00965	COG2906	2 iron, 2 sulfur cluster binding
C9I78_RS00975	COG0281	malic enzyme
C9I78_RS00985	COG0626	cystathionine gamma-synthase activity
C9I78_RS00990	COG0460	homoserine dehydrogenase
C9I78_RS00990	COG0527	aspartate kinase activity
C9I78_RS00995	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
C9I78_RS01005	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
C9I78_RS01010	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C9I78_RS01015	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
C9I78_RS01020	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
C9I78_RS01025	COG0137	argininosuccinate synthase activity
C9I78_RS01030	COG0165	Argininosuccinate lyase
C9I78_RS01030	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
C9I78_RS01045	COG0678	peroxiredoxin activity
C9I78_RS01045	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C9I78_RS01055	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
C9I78_RS01085	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
C9I78_RS01090	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
C9I78_RS01100	COG0338	D12 class N6 adenine-specific DNA methyltransferase
C9I78_RS01105	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C9I78_RS01115	COG0360	Binds together with S18 to 16S ribosomal RNA
C9I78_RS01120	COG2965	DNA replication, synthesis of RNA primer
C9I78_RS01130	COG0359	binds to the 23S rRNA
C9I78_RS01145	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C9I78_RS01155	COG0432	Pfam Uncharacterised protein family UPF0047
C9I78_RS01160	COG0166	Belongs to the GPI family
C9I78_RS01170	COG0735	belongs to the Fur family
C9I78_RS01180	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C9I78_RS01205	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
C9I78_RS01210	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C9I78_RS01215	COG0175	sulfate reduction
C9I78_RS01285	COG3335	DDE superfamily endonuclease
C9I78_RS01300	COG0646	methionine synthase
C9I78_RS01300	COG1410	methionine synthase
C9I78_RS01305	COG0527	aspartate kinase activity
C9I78_RS01315	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
C9I78_RS01325	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
C9I78_RS01340	COG0629	single-stranded DNA binding
C9I78_RS01370	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C9I78_RS01390	COG2199	diguanylate cyclase activity
C9I78_RS01390	COG2200	EAL domain
C9I78_RS01415	COG3409	Peptidoglycan-binding domain 1 protein
C9I78_RS01415	COG3267	Type II secretory pathway component ExeA
C9I78_RS01425	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C9I78_RS01430	COG1459	type II secretion system
C9I78_RS01440	COG2165	general secretion pathway protein
C9I78_RS01475	COG1077	Cell shape determining protein MreB Mrl
C9I78_RS01480	COG1792	Involved in formation and maintenance of cell shape
C9I78_RS01485	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
C9I78_RS01490	COG0424	maF-like protein
C9I78_RS01500	COG3164	Protein of unknown function
C9I78_RS01505	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C9I78_RS01510	COG0312	modulator of DNA gyrase
C9I78_RS01515	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
C9I78_RS01520	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
C9I78_RS01535	COG0564	pseudouridine synthase activity
C9I78_RS01540	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C9I78_RS01545	COG3028	Belongs to the UPF0307 family
C9I78_RS01550	COG0312	modulator of DNA gyrase
C9I78_RS01555	COG2239	Acts as a magnesium transporter
C9I78_RS01560	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C9I78_RS01565	COG1660	Displays ATPase and GTPase activities
C9I78_RS01570	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C9I78_RS01575	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
C9I78_RS01585	COG1137	ATPase activity
C9I78_RS01590	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
C9I78_RS01600	COG0517	IMP dehydrogenase activity
C9I78_RS01600	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
C9I78_RS01610	COG1127	ABC transporter
C9I78_RS01615	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
C9I78_RS01620	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
C9I78_RS01625	COG2854	intermembrane phospholipid transfer
C9I78_RS01635	COG5007	Belongs to the BolA IbaG family
C9I78_RS01640	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
C9I78_RS01645	COG0204	Acyl-transferase
C9I78_RS01650	COG0251	oxidation-reduction process
C9I78_RS01655	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
C9I78_RS01660	COG0540	Belongs to the ATCase OTCase family
C9I78_RS01670	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
C9I78_RS01675	COG2235	arginine
C9I78_RS01755	COG0525	valine-tRNA ligase activity
C9I78_RS01760	COG2927	DNA polymerase III (CHI subunit)
C9I78_RS01765	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
C9I78_RS01770	COG0795	lipopolysaccharide-transporting ATPase activity
C9I78_RS01775	COG0795	lipopolysaccharide-transporting ATPase activity
C9I78_RS01790	COG1028	Short-chain dehydrogenase reductase Sdr
C9I78_RS01805	COG0726	polysaccharide deacetylase
C9I78_RS01810	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C9I78_RS01815	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C9I78_RS01820	COG1447	Phosphotransferase system cellobiose-specific component IIA
C9I78_RS01825	COG1486	melibiose metabolic process
C9I78_RS01830	COG3394	polysaccharide catabolic process
C9I78_RS01840	COG3437	response regulator, receiver
C9I78_RS01890	COG1012	belongs to the aldehyde dehydrogenase family
C9I78_RS01920	COG0840	transmembrane signaling receptor activity
C9I78_RS01960	COG0741	lytic transglycosylase activity
C9I78_RS01965	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
C9I78_RS01975	COG0220	tRNA (guanine-N7-)-methyltransferase activity
C9I78_RS01985	COG2066	Belongs to the glutaminase family
C9I78_RS01990	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C9I78_RS01995	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
C9I78_RS02005	COG1872	DUF167
C9I78_RS02010	COG0762	integral membrane protein
C9I78_RS02015	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C9I78_RS02020	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
C9I78_RS02035	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
C9I78_RS02040	COG1678	Uncharacterized ACR, COG1678
C9I78_RS02045	COG0189	ligase activity
C9I78_RS02050	COG1385	rRNA (uridine-N3-)-methyltransferase activity
C9I78_RS02055	COG2356	endonuclease I
C9I78_RS02060	COG3091	SprT-like family
C9I78_RS02070	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
C9I78_RS02080	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
C9I78_RS02085	COG0583	DNA-binding transcription factor activity
C9I78_RS02090	COG4771	TonB-dependent receptor
C9I78_RS02095	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C9I78_RS02100	COG0126	phosphoglycerate kinase activity
C9I78_RS02105	COG0191	fructose-bisphosphate aldolase activity
C9I78_RS02110	COG0668	transmembrane transport
C9I78_RS02115	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C9I78_RS02125	COG0583	DNA-binding transcription factor activity
C9I78_RS02135	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C9I78_RS02140	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
C9I78_RS02145	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
C9I78_RS02155	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
C9I78_RS02165	COG3079	Belongs to the UPF0149 family
C9I78_RS02170	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C9I78_RS02175	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C9I78_RS02190	COG0354	folic acid binding
C9I78_RS02195	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
C9I78_RS02205	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
C9I78_RS02215	COG1595	DNA-templated transcription, initiation
C9I78_RS02220	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
C9I78_RS02230	COG3086	response to oxidative stress
C9I78_RS02235	COG0481	GTPase activity
C9I78_RS02245	COG0571	ribonuclease III activity
C9I78_RS02250	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
C9I78_RS02255	COG1381	Involved in DNA repair and RecF pathway recombination
C9I78_RS02260	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
C9I78_RS02265	COG0736	holo-[acyl-carrier-protein] synthase activity
C9I78_RS02280	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C9I78_RS02290	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C9I78_RS02295	COG3956	TIGRFAM MazG family protein
C9I78_RS02300	COG0504	CTP synthase activity
C9I78_RS02305	COG0148	phosphopyruvate hydratase activity
C9I78_RS02310	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
C9I78_RS02315	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
C9I78_RS02320	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
C9I78_RS02325	COG0585	pseudouridine synthase activity
C9I78_RS02330	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
C9I78_RS02335	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
C9I78_RS02350	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
C9I78_RS02355	COG1546	Belongs to the CinA family
C9I78_RS02365	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
C9I78_RS02430	COG2137	regulation of response to DNA damage stimulus
C9I78_RS02435	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
C9I78_RS02440	COG0527	aspartate kinase activity
C9I78_RS02500	COG3630	sodium ion export across plasma membrane
C9I78_RS02505	COG5016	pyruvate
C9I78_RS02505	COG0511	ligase activity, forming carbon-carbon bonds
C9I78_RS02510	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
C9I78_RS02520	COG1238	metal cluster binding
C9I78_RS02525	COG0612	Peptidase, M16
C9I78_RS02530	COG2918	glutathione biosynthetic process
C9I78_RS02540	COG1854	S-ribosylhomocysteine lyase activity
C9I78_RS02545	COG4536	flavin adenine dinucleotide binding
C9I78_RS02550	COG4137	Cytochrome C assembly protein
C9I78_RS02555	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
C9I78_RS02560	COG0228	four-way junction DNA binding
C9I78_RS02565	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
C9I78_RS02580	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
C9I78_RS02585	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
C9I78_RS02590	COG0237	dephospho-CoA kinase activity
C9I78_RS02600	COG1459	type II secretion system
C9I78_RS02605	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C9I78_RS02615	COG0157	Belongs to the NadC ModD family
C9I78_RS02625	COG2186	Transcriptional regulator
C9I78_RS02630	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
C9I78_RS02635	COG0508	dehydrogenase complex catalyzes the overall conversion of
C9I78_RS02640	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C9I78_RS02655	COG0288	reversible hydration of carbon dioxide
C9I78_RS02660	COG0659	secondary active sulfate transmembrane transporter activity
C9I78_RS02670	COG1131	(ABC) transporter
C9I78_RS02675	COG0842	Transport permease protein
C9I78_RS02685	COG1560	Kdo2-lipid A biosynthetic process
C9I78_RS02695	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
C9I78_RS02700	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
C9I78_RS02705	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C9I78_RS02720	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C9I78_RS02735	COG1489	DNA binding
C9I78_RS02775	COG3550	peptidyl-serine autophosphorylation
C9I78_RS02845	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C9I78_RS02850	COG1752	Esterase of the alpha-beta hydrolase superfamily
C9I78_RS02855	COG1049	propionate catabolic process, 2-methylcitrate cycle
C9I78_RS02860	COG3112	Uncharacterised protein family (UPF0231)
C9I78_RS02870	COG0004	ammonium transporteR
C9I78_RS02875	COG1840	ABC-type Fe3 transport system, periplasmic component
C9I78_RS02885	COG3842	ATPase activity
C9I78_RS02890	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C9I78_RS02905	COG2971	BadF BadG BcrA BcrD
C9I78_RS02915	COG4608	Belongs to the ABC transporter superfamily
C9I78_RS02920	COG0444	Belongs to the ABC transporter superfamily
C9I78_RS02925	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C9I78_RS02935	COG0747	negative chemotaxis
C9I78_RS02940	COG0784	Response regulator, receiver
C9I78_RS02940	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C9I78_RS02940	COG2198	Histidine kinase
C9I78_RS02940	COG2205	protein histidine kinase activity
C9I78_RS02950	COG2813	Specifically methylates the guanine in position
C9I78_RS02955	COG0628	permease
C9I78_RS02960	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
C9I78_RS02965	COG0316	Belongs to the HesB IscA family
C9I78_RS02975	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C9I78_RS02980	COG0739	heme binding
C9I78_RS02985	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
C9I78_RS02995	COG2027	D-alanyl-D-alanine carboxypeptidase
C9I78_RS03000	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
C9I78_RS03005	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C9I78_RS03010	COG1534	Rna-binding protein
C9I78_RS03015	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
C9I78_RS03020	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C9I78_RS03025	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
C9I78_RS03030	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C9I78_RS03040	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C9I78_RS03055	COG0779	Required for maturation of 30S ribosomal subunits
C9I78_RS03060	COG0195	Participates in both transcription termination and antitermination
C9I78_RS03065	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
C9I78_RS03070	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
C9I78_RS03075	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
C9I78_RS03080	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
C9I78_RS03085	COG1185	polyribonucleotide nucleotidyltransferase activity
C9I78_RS03100	COG0534	Mate efflux family protein
C9I78_RS03105	COG0826	peptidase U32
C9I78_RS03110	COG0826	peptidase U32
C9I78_RS03120	COG3154	lipid carrier protein
C9I78_RS03125	COG3153	acetyltransferase
C9I78_RS03145	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
C9I78_RS03155	COG0084	hydrolase, TatD family'
C9I78_RS03160	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C9I78_RS03165	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
C9I78_RS03170	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
C9I78_RS03175	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
C9I78_RS03180	COG0813	purine-nucleoside phosphorylase activity
C9I78_RS03190	COG0560	Phosphoserine phosphatase
C9I78_RS03200	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
C9I78_RS03205	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
C9I78_RS03210	COG0583	DNA-binding transcription factor activity
C9I78_RS03225	COG2169	Transcriptional regulator
C9I78_RS03250	COG4964	Belongs to the GSP D family
C9I78_RS03310	COG0583	DNA-binding transcription factor activity
C9I78_RS03315	COG0531	amino acid
C9I78_RS03320	COG2731	YhcH YjgK YiaL family protein
C9I78_RS03325	COG3250	beta-galactosidase activity
C9I78_RS03330	COG1609	Transcriptional regulator
C9I78_RS03340	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C9I78_RS03350	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
C9I78_RS03355	COG2017	converts alpha-aldose to the beta-anomer
C9I78_RS03370	COG2211	Major facilitator Superfamily
C9I78_RS03375	COG1609	Transcriptional regulator
C9I78_RS03380	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C9I78_RS03395	COG0598	Magnesium transport protein CorA
C9I78_RS03400	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
C9I78_RS03405	COG1349	DNA-binding transcription factor activity
C9I78_RS03410	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
C9I78_RS03415	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C9I78_RS03430	COG2271	Major facilitator Superfamily
C9I78_RS03435	COG0584	glycerophosphoryl diester phosphodiesterase
C9I78_RS03440	COG2171	N-acyltransferase activity
C9I78_RS03445	COG3141	response to X-ray
C9I78_RS03465	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
C9I78_RS03475	COG1074	ATP-dependent DNA helicase activity
C9I78_RS03480	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C9I78_RS03490	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
C9I78_RS03490	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
C9I78_RS03505	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
C9I78_RS03510	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
C9I78_RS03515	COG2166	iron-sulfur cluster assembly
C9I78_RS03520	COG3706	GGDEF domain
C9I78_RS03525	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C9I78_RS03530	COG0693	protein deglycase activity
C9I78_RS03535	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
C9I78_RS03560	COG1595	DNA-templated transcription, initiation
C9I78_RS03580	COG3056	Lipoprotein
C9I78_RS03585	COG2813	Specifically methylates the guanine in position
C9I78_RS03590	COG0271	Belongs to the BolA IbaG family
C9I78_RS03600	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
C9I78_RS03605	COG1805	sodium ion transport
C9I78_RS03610	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
C9I78_RS03615	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
C9I78_RS03620	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
C9I78_RS03625	COG2871	sodium ion transport
C9I78_RS03630	COG1477	protein flavinylation
C9I78_RS03645	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C9I78_RS03650	COG0514	ATP-dependent DNA helicase (RecQ)
C9I78_RS03670	COG0733	neurotransmitter:sodium symporter activity
C9I78_RS03690	COG0442	prolyl-tRNA aminoacylation
C9I78_RS03695	COG1720	tRNA m6t6A37 methyltransferase activity
C9I78_RS03700	COG0254	rRNA binding
C9I78_RS03715	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
C9I78_RS03720	COG1671	Belongs to the UPF0178 family
C9I78_RS03745	COG3098	single-species biofilm formation
C9I78_RS03750	COG0564	pseudouridine synthase activity
C9I78_RS03760	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
C9I78_RS03765	COG0024	Methionine aminopeptidase
C9I78_RS03770	COG0052	Belongs to the universal ribosomal protein uS2 family
C9I78_RS03775	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
C9I78_RS03780	COG0528	UMP kinase activity
C9I78_RS03785	COG0233	cytoplasmic translational termination
C9I78_RS03790	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
C9I78_RS03795	COG0575	Belongs to the CDS family
C9I78_RS03800	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
C9I78_RS03805	COG0750	zinc metalloprotease
C9I78_RS03815	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
C9I78_RS03820	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C9I78_RS03825	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
C9I78_RS03830	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C9I78_RS03835	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C9I78_RS03840	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
C9I78_RS03845	COG0587	DNA-directed DNA polymerase activity
C9I78_RS03850	COG0825	malonyl-CoA metabolic process
C9I78_RS03855	COG0037	tRNA processing
C9I78_RS03865	COG0347	Belongs to the P(II) protein family
C9I78_RS03870	COG3021	interspecies interaction between organisms
C9I78_RS03880	COG1388	LysM domain
C9I78_RS03880	COG0741	lytic transglycosylase activity
C9I78_RS03885	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C9I78_RS03890	COG2226	methyltransferase
C9I78_RS03895	COG0328	RNA-DNA hybrid ribonuclease activity
C9I78_RS03900	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C9I78_RS03930	COG1960	acyl-CoA dehydrogenase activity
C9I78_RS03935	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
C9I78_RS03940	COG0121	glutamine amidotransferase
C9I78_RS03945	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
C9I78_RS03950	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
C9I78_RS03955	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
C9I78_RS03960	COG2233	PERMEase
C9I78_RS03980	COG1393	Belongs to the ArsC family
C9I78_RS03985	COG4783	chaperone-mediated protein folding
C9I78_RS04000	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C9I78_RS04005	COG2716	regulation of RNA biosynthetic process
C9I78_RS04010	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C9I78_RS04015	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
C9I78_RS04030	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C9I78_RS04035	COG1393	Belongs to the ArsC family
C9I78_RS04065	COG2837	iron assimilation
C9I78_RS04070	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C9I78_RS04080	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C9I78_RS04085	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C9I78_RS04090	COG1334	flagellar protein FlaG
C9I78_RS04095	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
C9I78_RS04105	COG1516	flagellar protein fliS
C9I78_RS04125	COG1677	Flagellar hook-basal body complex protein FliE
C9I78_RS04135	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C9I78_RS04185	COG1987	bacterial-type flagellum assembly
C9I78_RS04190	COG1684	flagellar biosynthetic protein fliR
C9I78_RS04225	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
C9I78_RS04230	COG0784	Response regulator, receiver
C9I78_RS04230	COG0643	Histidine kinase
C9I78_RS04230	COG2198	Histidine kinase
C9I78_RS04235	COG2201	protein-glutamate methylesterase activity
C9I78_RS04240	COG1192	Involved in chromosome partitioning
C9I78_RS04250	COG0835	chemotaxis
C9I78_RS04260	COG4133	protoheme IX ABC transporter activity
C9I78_RS04265	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C9I78_RS04270	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C9I78_RS04275	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C9I78_RS04280	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
C9I78_RS04285	COG1138	Cytochrome C-type biogenesis protein
C9I78_RS04290	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C9I78_RS04305	COG2853	Lipoprotein
C9I78_RS04315	COG2067	long-chain fatty acid transport protein
C9I78_RS04335	COG0183	Belongs to the thiolase family
C9I78_RS04340	COG1250	3-hydroxyacyl-CoA dehydrogenase
C9I78_RS04340	COG1024	Enoyl-CoA hydratase
C9I78_RS04355	COG2062	phosphohistidine phosphatase, SixA
C9I78_RS04360	COG2840	Smr protein MutS2
C9I78_RS04365	COG2890	protein-(glutamine-N5) methyltransferase activity
C9I78_RS04370	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
C9I78_RS04375	COG2860	membrane
C9I78_RS04385	COG3101	peptidyl-lysine hydroxylation
C9I78_RS04400	COG0431	NADPH-dependent FMN reductase
C9I78_RS04405	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
C9I78_RS04405	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C9I78_RS04410	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C9I78_RS04420	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C9I78_RS04425	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C9I78_RS04435	COG0101	tRNA pseudouridine synthase activity
C9I78_RS04440	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
C9I78_RS04445	COG0285	dihydrofolate synthase activity
C9I78_RS04450	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
C9I78_RS04455	COG1286	toxin biosynthetic process
C9I78_RS04460	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
C9I78_RS04465	COG0583	DNA-binding transcription factor activity
C9I78_RS04470	COG0745	RESPONSE REGULATOR receiver
C9I78_RS04480	COG2832	Protein of unknown function (DUF454)
C9I78_RS04485	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C9I78_RS04495	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
C9I78_RS04500	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
C9I78_RS04505	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C9I78_RS04510	COG0814	amino acid
C9I78_RS04515	COG0251	oxidation-reduction process
C9I78_RS04520	COG3681	Belongs to the UPF0597 family
C9I78_RS04535	COG2261	transglycosylase associated protein
C9I78_RS04540	COG2983	Belongs to the UPF0260 family
C9I78_RS04545	COG0668	transmembrane transport
C9I78_RS04550	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
C9I78_RS04555	COG0346	lactoylglutathione lyase activity
C9I78_RS04565	COG1785	Belongs to the alkaline phosphatase family
C9I78_RS04585	COG2226	methyltransferase
C9I78_RS04600	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C9I78_RS04605	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C9I78_RS04615	COG3139	Protein of unknown function (DUF1315)
C9I78_RS04620	COG0252	asparaginase activity
C9I78_RS04625	COG0616	signal peptide processing
C9I78_RS04630	COG0446	pyridine nucleotide-disulphide oxidoreductase
C9I78_RS04630	COG1902	pentaerythritol trinitrate reductase activity
C9I78_RS04635	COG0778	Nitroreductase
C9I78_RS04640	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C9I78_RS04660	COG0123	including yeast histone deacetylase and acetoin utilization protein
C9I78_RS04670	COG3083	sulfuric ester hydrolase activity
C9I78_RS04675	COG3082	Protein of unknown function (DUF1414)
C9I78_RS04680	COG3081	Nucleoid-associated protein
C9I78_RS04695	COG1757	Na H antiporter
C9I78_RS04700	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C9I78_RS04705	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C9I78_RS04710	COG2095	MarC family integral membrane protein
C9I78_RS04715	COG1012	belongs to the aldehyde dehydrogenase family
C9I78_RS04715	COG1454	alcohol dehydrogenase
C9I78_RS04735	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
C9I78_RS04745	COG2056	Na+-H+ antiporter family
C9I78_RS04750	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C9I78_RS04765	COG2885	chlorophyll binding
C9I78_RS04775	COG0346	lactoylglutathione lyase activity
C9I78_RS04780	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
C9I78_RS04785	COG4660	Part of a membrane complex involved in electron transport
C9I78_RS04790	COG4659	FMN binding
C9I78_RS04795	COG4658	electron transport chain
C9I78_RS04800	COG4656	Part of a membrane complex involved in electron transport
C9I78_RS04805	COG2878	Part of a membrane complex involved in electron transport
C9I78_RS04810	COG4657	Part of a membrane complex involved in electron transport
C9I78_RS04825	COG0556	nucleotide-excision repair
C9I78_RS04830	COG2204	response regulator
C9I78_RS04835	COG2198	Histidine kinase
C9I78_RS04840	COG0391	Required for morphogenesis under gluconeogenic growth conditions
C9I78_RS04845	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
C9I78_RS04850	COG0521	Mo-molybdopterin cofactor biosynthetic process
C9I78_RS04855	COG0315	cyclic pyranopterin monophosphate synthase activity
C9I78_RS04860	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
C9I78_RS04865	COG0314	molybdopterin synthase activity
C9I78_RS04875	COG0601	transmembrane transport
C9I78_RS04880	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C9I78_RS04885	COG0444	Belongs to the ABC transporter superfamily
C9I78_RS04895	COG0435	Glutathione S-transferase
C9I78_RS04905	COG3174	membrane
C9I78_RS04910	COG0280	phosphate acetyltransferase
C9I78_RS04910	COG0857	belongs to the CobB CobQ family
C9I78_RS04915	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
C9I78_RS04920	COG3092	negative regulation of chromosome organization
C9I78_RS04930	COG4120	Belongs to the binding-protein-dependent transport system permease family
C9I78_RS04935	COG1122	ATPase activity
C9I78_RS04940	COG0366	Alpha amylase catalytic
C9I78_RS04950	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C9I78_RS04955	COG0653	protein targeting
C9I78_RS04960	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
C9I78_RS04965	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
C9I78_RS04970	COG2186	Transcriptional regulator
C9I78_RS04980	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C9I78_RS04980	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C9I78_RS04985	COG0489	protein tyrosine kinase activity
C9I78_RS04990	COG0572	uridine kinase
C9I78_RS05000	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
C9I78_RS05005	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C9I78_RS05010	COG0659	secondary active sulfate transmembrane transporter activity
C9I78_RS05020	COG1530	ribonuclease E activity
C9I78_RS05035	COG0564	pseudouridine synthase activity
C9I78_RS05040	COG0424	maF-like protein
C9I78_RS05045	COG1399	metal-binding, possibly nucleic acid-binding protein
C9I78_RS05055	COG0416	fatty acid biosynthetic process
C9I78_RS05060	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C9I78_RS05090	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C9I78_RS05095	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
C9I78_RS05105	COG0084	hydrolase, TatD family'
C9I78_RS05110	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C9I78_RS05110	COG1263	PTS System
C9I78_RS05130	COG0733	neurotransmitter:sodium symporter activity
C9I78_RS05145	COG4667	esterase of the alpha-beta hydrolase superfamily
C9I78_RS05150	COG0469	pyruvate kinase activity
C9I78_RS05155	COG1940	carbohydrate kinase activity
C9I78_RS05160	COG0835	chemotaxis
C9I78_RS05160	COG0784	Response regulator, receiver
C9I78_RS05165	COG0587	DNA-directed DNA polymerase activity
C9I78_RS05180	COG1028	Short-chain dehydrogenase reductase Sdr
C9I78_RS05185	COG0616	signal peptide processing
C9I78_RS05190	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
C9I78_RS05195	COG0539	negative regulation of cytoplasmic translation
C9I78_RS05205	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
C9I78_RS05210	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
C9I78_RS05215	COG0284	orotidine-5'-phosphate decarboxylase activity
C9I78_RS05220	COG4166	transmembrane transport
C9I78_RS05245	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
C9I78_RS05255	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
C9I78_RS05255	COG3008	intermembrane lipid transfer
C9I78_RS05260	COG2995	paraquat-inducible protein a
C9I78_RS05265	COG3258	Cytochrome c
C9I78_RS05270	COG2863	cytochrome
C9I78_RS05310	COG4232	protein-disulfide reductase activity
C9I78_RS05315	COG3118	belongs to the thioredoxin family
C9I78_RS05345	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C9I78_RS05355	COG0577	efflux transmembrane transporter activity
C9I78_RS05355	COG1136	(ABC) transporter
C9I78_RS05360	COG1136	(ABC) transporter
C9I78_RS05360	COG0577	efflux transmembrane transporter activity
C9I78_RS05365	COG1136	(ABC) transporter
C9I78_RS05365	COG0577	efflux transmembrane transporter activity
C9I78_RS05370	COG1335	isochorismatase
C9I78_RS05420	COG3850	Histidine kinase
C9I78_RS05420	COG5002	protein histidine kinase activity
C9I78_RS05425	COG0745	RESPONSE REGULATOR receiver
C9I78_RS05435	COG0840	transmembrane signaling receptor activity
C9I78_RS05440	COG1032	radical SAM domain protein
C9I78_RS05445	COG3706	GGDEF domain
C9I78_RS05445	COG4251	negative regulation of phosphorylation
C9I78_RS05445	COG2203	Gaf domain
C9I78_RS05445	COG5001	Diguanylate cyclase
C9I78_RS05460	COG0583	DNA-binding transcription factor activity
C9I78_RS05470	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
C9I78_RS05480	COG2350	Protein conserved in bacteria
C9I78_RS05490	COG2917	probably involved in intracellular septation
C9I78_RS05510	COG1301	dicarboxylic acid transport
C9I78_RS05520	COG0318	PFAM AMP-dependent synthetase and ligase
C9I78_RS05525	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C9I78_RS05530	COG0159	tryptophan synthase activity
C9I78_RS05535	COG0133	tryptophan synthase activity
C9I78_RS05540	COG0135	phosphoribosylanthranilate isomerase activity
C9I78_RS05540	COG0134	indole-3-glycerol-phosphate synthase activity
C9I78_RS05545	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
C9I78_RS05550	COG0512	Glutamine amidotransferase of anthranilate synthase
C9I78_RS05555	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C9I78_RS05565	COG0613	PHP domain protein
C9I78_RS05570	COG0009	L-threonylcarbamoyladenylate synthase
C9I78_RS05580	COG1187	pseudouridine synthase activity
C9I78_RS05590	COG3099	Belongs to the UPF0263 family
C9I78_RS05595	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
C9I78_RS05605	COG0417	DNA replication proofreading
C9I78_RS05610	COG2197	response regulator
C9I78_RS05615	COG0322	excinuclease ABC activity
C9I78_RS05655	COG0019	diaminopimelate decarboxylase activity
C9I78_RS05680	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C9I78_RS05685	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C9I78_RS05690	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C9I78_RS05710	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
C9I78_RS05720	COG0437	4 iron, 4 sulfur cluster binding
C9I78_RS05725	COG3301	Polysulphide reductase, NrfD
C9I78_RS05730	COG1138	Cytochrome C-type biogenesis protein
C9I78_RS05740	COG3088	subunit of a heme lyase
C9I78_RS05740	COG4235	cytochrome complex assembly
C9I78_RS05750	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C9I78_RS05775	COG2989	Protein conserved in bacteria
C9I78_RS05780	COG3108	Peptidase M15
C9I78_RS05785	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C9I78_RS05800	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
C9I78_RS05825	COG1846	Transcriptional regulator
C9I78_RS05830	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C9I78_RS05835	COG0840	transmembrane signaling receptor activity
C9I78_RS05855	COG1448	Aminotransferase
C9I78_RS05880	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C9I78_RS05890	COG0017	Asparaginyl-tRNA synthetase
C9I78_RS05900	COG0720	synthase
C9I78_RS05910	COG2200	EAL domain
C9I78_RS05915	COG1760	l-serine dehydratase
C9I78_RS05920	COG0814	amino acid
C9I78_RS05925	COG0494	nUDIX hydrolase
C9I78_RS05940	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C9I78_RS05960	COG3106	COG3106 Predicted ATPase
C9I78_RS05965	COG3768	UPF0283 membrane protein
C9I78_RS05975	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C9I78_RS06015	COG2801	Transposase and inactivated derivatives
C9I78_RS06070	COG1011	Hydrolase
C9I78_RS06115	COG2732	(Barnase) inhibitor
C9I78_RS06155	COG0346	lactoylglutathione lyase activity
C9I78_RS06450	COG0346	lactoylglutathione lyase activity
C9I78_RS06595	COG0346	lactoylglutathione lyase activity
C9I78_RS06660	COG2161	toxin-antitoxin pair type II binding
C9I78_RS06665	COG4115	mRNA cleavage
C9I78_RS06730	COG1757	Na H antiporter
C9I78_RS06735	COG0174	glutamine synthetase
C9I78_RS06745	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
C9I78_RS06750	COG1396	sequence-specific DNA binding
C9I78_RS06750	COG1917	Cupin 2, conserved barrel domain protein
C9I78_RS06755	COG1012	belongs to the aldehyde dehydrogenase family
C9I78_RS06760	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C9I78_RS06770	COG2957	Belongs to the agmatine deiminase family
C9I78_RS06775	COG1012	belongs to the aldehyde dehydrogenase family
C9I78_RS06780	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C9I78_RS06785	COG1227	inorganic diphosphatase activity
C9I78_RS06795	COG2771	luxR family
C9I78_RS06795	COG2200	EAL domain
C9I78_RS06820	COG1846	Transcriptional regulator
C9I78_RS06825	COG2315	Protein conserved in bacteria
C9I78_RS06845	COG0110	maltose O-acetyltransferase activity
C9I78_RS06875	COG3063	Type IV pilus biogenesis stability protein PilW
C9I78_RS06880	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
C9I78_RS06895	COG0531	amino acid
C9I78_RS06905	COG1560	Kdo2-lipid A biosynthetic process
C9I78_RS06910	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
C9I78_RS06915	COG1280	lysine exporter protein (LysE YggA)
C9I78_RS06925	COG1115	amino acid carrier protein
C9I78_RS06950	COG1368	sulfuric ester hydrolase activity
C9I78_RS06955	COG0642	Histidine kinase
C9I78_RS06960	COG0745	RESPONSE REGULATOR receiver
C9I78_RS06970	COG1028	Short-chain dehydrogenase reductase Sdr
C9I78_RS06980	COG1022	Amp-dependent synthetase and ligase
C9I78_RS06990	COG2113	Glycine betaine
C9I78_RS06995	COG4176	ABC-type proline glycine betaine transport system permease component
C9I78_RS07015	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C9I78_RS07020	COG0456	acetyltransferase
C9I78_RS07025	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C9I78_RS07030	COG0662	Cupin 2, conserved barrel domain protein
C9I78_RS07035	COG0527	aspartate kinase activity
C9I78_RS07050	COG1858	cytochrome C peroxidase
C9I78_RS07065	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C9I78_RS07080	COG3290	protein histidine kinase activity
C9I78_RS07085	COG4565	transcriptional regulatory protein
C9I78_RS07090	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
C9I78_RS07095	COG0363	glucosamine-6-phosphate deaminase activity
C9I78_RS07100	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
C9I78_RS07115	COG3284	Transcriptional regulator
C9I78_RS07120	COG1012	belongs to the aldehyde dehydrogenase family
C9I78_RS07190	COG4669	(LipO)protein
C9I78_RS07210	COG3177	Filamentation induced by cAMP protein fic
C9I78_RS07260	COG4792	protein secretion
C9I78_RS07265	COG4791	protein targeting
C9I78_RS07270	COG4794	Type iii secretion
C9I78_RS07275	COG4790	Type iii secretion
C9I78_RS07345	COG0457	Tetratricopeptide repeat
C9I78_RS07365	COG0730	response to heat
C9I78_RS07395	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
C9I78_RS07400	COG0372	Belongs to the citrate synthase family
C9I78_RS07410	COG2828	Protein conserved in bacteria
C9I78_RS07435	COG0561	phosphatase activity
C9I78_RS07440	COG0602	queuosine metabolic process
C9I78_RS07445	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
C9I78_RS07450	COG3706	GGDEF domain
C9I78_RS07490	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
C9I78_RS07495	COG0840	transmembrane signaling receptor activity
C9I78_RS07500	COG1254	Belongs to the acylphosphatase family
C9I78_RS07505	COG2920	part of a sulfur-relay system
C9I78_RS07515	COG0670	Belongs to the BI1 family
C9I78_RS07520	COG1126	abc transporter atp-binding protein
C9I78_RS07525	COG0765	amino acid transport
C9I78_RS07530	COG4597	amino acid ABC transporter
C9I78_RS07535	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C9I78_RS07555	COG1666	GTP binding
C9I78_RS07560	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C9I78_RS07580	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
C9I78_RS07580	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
C9I78_RS07590	COG3008	intermembrane lipid transfer
C9I78_RS07595	COG2995	paraquat-inducible protein a
C9I78_RS07600	COG1132	(ABC) transporter
C9I78_RS07605	COG1956	GAF domain-containing protein
C9I78_RS07610	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
C9I78_RS07625	COG0308	aminopeptidase N
C9I78_RS07635	COG2902	Dehydrogenase
C9I78_RS07640	COG0167	dihydroorotate dehydrogenase activity
C9I78_RS07655	COG0116	Belongs to the methyltransferase superfamily
C9I78_RS07655	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
C9I78_RS07665	COG0488	(ABC) transporter
C9I78_RS07680	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
C9I78_RS07685	COG1067	ATP-dependent peptidase activity
C9I78_RS07690	COG3120	sequence-specific DNA binding
C9I78_RS07835	COG2205	protein histidine kinase activity
C9I78_RS07835	COG0784	Response regulator, receiver
C9I78_RS07850	COG3278	Belongs to the heme-copper respiratory oxidase family
C9I78_RS07865	COG2010	Cytochrome c
C9I78_RS07875	COG2217	Heavy metal translocating P-type atpase
C9I78_RS07890	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C9I78_RS07895	COG0589	response to stress
C9I78_RS07905	COG0037	tRNA processing
C9I78_RS07925	COG3842	ATPase activity
C9I78_RS07935	COG1177	transmembrane transport
C9I78_RS07945	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
C9I78_RS07950	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
C9I78_RS07960	COG0004	ammonium transporteR
C9I78_RS08015	COG0437	4 iron, 4 sulfur cluster binding
C9I78_RS08020	COG3383	formate dehydrogenase (NAD+) activity
C9I78_RS08020	COG0243	molybdopterin cofactor binding
C9I78_RS08030	COG3381	protein complex oligomerization
C9I78_RS08055	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
C9I78_RS08060	COG0488	(ABC) transporter
C9I78_RS08070	COG4191	Histidine kinase
C9I78_RS08075	COG2204	response regulator
C9I78_RS08095	COG3842	ATPase activity
C9I78_RS08100	COG0746	molybdenum cofactor guanylyltransferase activity
C9I78_RS08105	COG0303	'Molybdopterin
C9I78_RS08115	COG1940	carbohydrate kinase activity
C9I78_RS08120	COG3148	PFAM DTW domain containing protein
C9I78_RS08155	COG3290	protein histidine kinase activity
C9I78_RS08155	COG0840	transmembrane signaling receptor activity
C9I78_RS08160	COG0791	NLP P60 protein
C9I78_RS08170	COG3706	GGDEF domain
C9I78_RS08175	COG2201	protein-glutamate methylesterase activity
C9I78_RS08180	COG3001	Fructosamine kinase
C9I78_RS08190	COG0307	riboflavin synthase, alpha
C9I78_RS08195	COG0534	Mate efflux family protein
C9I78_RS08205	COG1793	dna ligase
C9I78_RS08240	COG2204	response regulator
C9I78_RS08285	COG0438	transferase activity, transferring glycosyl groups
C9I78_RS08290	COG1215	transferase activity, transferring glycosyl groups
C9I78_RS08295	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
C9I78_RS08305	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C9I78_RS08320	COG1643	Atp-dependent helicase
C9I78_RS08325	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
C9I78_RS08335	COG3381	protein complex oligomerization
C9I78_RS08340	COG3302	dmso reductase anchor subunit
C9I78_RS08345	COG0437	4 iron, 4 sulfur cluster binding
C9I78_RS08350	COG0243	molybdopterin cofactor binding
C9I78_RS08380	COG3706	GGDEF domain
C9I78_RS08390	COG0443	Heat shock 70 kDa protein
C9I78_RS08395	COG0443	Heat shock 70 kDa protein
C9I78_RS08425	COG1132	(ABC) transporter
C9I78_RS08430	COG1132	(ABC) transporter
C9I78_RS08455	COG0814	amino acid
C9I78_RS08470	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
C9I78_RS08565	COG1522	sequence-specific DNA binding
C9I78_RS08600	COG0515	serine threonine protein kinase
C9I78_RS08625	COG3501	Rhs element vgr protein
C9I78_RS08645	COG2885	chlorophyll binding
C9I78_RS08665	COG0739	heme binding
C9I78_RS08675	COG0861	Integral membrane protein TerC family
C9I78_RS08685	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C9I78_RS08690	COG1328	CTP reductase activity
C9I78_RS08695	COG1280	lysine exporter protein (LysE YggA)
C9I78_RS08705	COG5001	Diguanylate cyclase
C9I78_RS08705	COG3300	MHYT domain
C9I78_RS08715	COG4191	Histidine kinase
C9I78_RS08715	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C9I78_RS08720	COG0471	metal ion transport
C9I78_RS08755	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C9I78_RS08760	COG0583	DNA-binding transcription factor activity
C9I78_RS08775	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
C9I78_RS08780	COG1982	Orn Lys Arg decarboxylase major
C9I78_RS08790	COG0531	amino acid
C9I78_RS08800	COG0531	amino acid
C9I78_RS08830	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
C9I78_RS08830	COG3264	Mechanosensitive ion channel
C9I78_RS08845	COG1127	ABC transporter
C9I78_RS08850	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
C9I78_RS08890	COG0625	glutathione transferase activity
C9I78_RS08900	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
C9I78_RS08915	COG2195	Cleaves the N-terminal amino acid of tripeptides
C9I78_RS08925	COG0601	transmembrane transport
C9I78_RS08930	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C9I78_RS08935	COG0444	Belongs to the ABC transporter superfamily
C9I78_RS08955	COG3291	Pkd domain containing protein
C9I78_RS08970	COG1177	transmembrane transport
C9I78_RS08975	COG1176	ABC-type spermidine putrescine transport system, permease component I
C9I78_RS08980	COG3842	ATPase activity
C9I78_RS08985	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C9I78_RS08990	COG2423	ornithine cyclodeaminase activity
C9I78_RS09010	COG3938	Belongs to the proline racemase family
C9I78_RS09040	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
C9I78_RS09045	COG1451	nucleotide metabolic process
C9I78_RS09050	COG3475	LICD family
C9I78_RS09055	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C9I78_RS09060	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
C9I78_RS09080	COG0583	DNA-binding transcription factor activity
C9I78_RS09100	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
C9I78_RS09105	COG4139	cobalamin transport
C9I78_RS09110	COG2988	succinylglutamate desuccinylase activity
C9I78_RS09125	COG2062	phosphohistidine phosphatase, SixA
C9I78_RS09135	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
C9I78_RS09140	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
C9I78_RS09145	COG0702	epimerase
C9I78_RS09150	COG1823	symporter activity
C9I78_RS09155	COG2925	Exonuclease
C9I78_RS09160	COG1380	Effector of murein hydrolase LrgA
C9I78_RS09165	COG1346	cytolysis
C9I78_RS09170	COG0295	cytidine deaminase activity
C9I78_RS09175	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
C9I78_RS09180	COG0500	methyltransferase
C9I78_RS09190	COG0776	regulation of translation
C9I78_RS09205	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C9I78_RS09205	COG0072	phenylalanine-tRNA ligase activity
C9I78_RS09210	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
C9I78_RS09215	COG3706	GGDEF domain
C9I78_RS09245	COG0393	Putative heavy-metal-binding
C9I78_RS09255	COG0291	Belongs to the bacterial ribosomal protein bL35 family
C9I78_RS09265	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
C9I78_RS09280	COG2188	Transcriptional regulator
C9I78_RS09285	COG1228	amidohydrolase
C9I78_RS09290	COG0010	Belongs to the arginase family
C9I78_RS09295	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
C9I78_RS09300	COG2986	histidine ammonia-lyase
C9I78_RS09315	COG0247	lactate metabolic process
C9I78_RS09315	COG0277	FAD linked oxidase domain protein
C9I78_RS09350	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
C9I78_RS09365	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
C9I78_RS09370	COG1643	Atp-dependent helicase
C9I78_RS09375	COG0281	malic enzyme
C9I78_RS09380	COG2949	membrane
C9I78_RS09385	COG0471	metal ion transport
C9I78_RS09410	COG0492	ferredoxin-NADP+ reductase activity
C9I78_RS09415	COG4988	ABC transporter
C9I78_RS09420	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
C9I78_RS09425	COG3048	D-serine ammonia-lyase activity
C9I78_RS09430	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
C9I78_RS09440	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C9I78_RS09440	COG4191	Histidine kinase
C9I78_RS09455	COG3070	regulator of competence-specific genes
C9I78_RS09475	COG2431	L-lysine efflux transmembrane transporter activity
C9I78_RS09485	COG0076	glutamate decarboxylase activity
C9I78_RS09490	COG1737	Transcriptional regulator
C9I78_RS09505	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C9I78_RS09510	COG3273	potassium ion transport
C9I78_RS09510	COG2985	domain, Protein
C9I78_RS09515	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
C9I78_RS09530	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
C9I78_RS09545	COG4181	ATPase activity
C9I78_RS09550	COG0534	Mate efflux family protein
C9I78_RS09555	COG0702	epimerase
C9I78_RS09560	COG3005	denitrification pathway
C9I78_RS09590	COG2814	Major facilitator Superfamily
C9I78_RS09595	COG1187	pseudouridine synthase activity
C9I78_RS09600	COG1061	Type III restriction enzyme res subunit
C9I78_RS09620	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
C9I78_RS09650	COG3313	Fe-S protein
C9I78_RS09675	COG0493	'glutamate synthase
C9I78_RS09685	COG0398	Pfam SNARE associated Golgi protein
C9I78_RS09690	COG4134	Bacterial extracellular solute-binding protein
C9I78_RS09695	COG4135	transport system, permease component
C9I78_RS09700	COG4136	ATPase activity
C9I78_RS09705	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
C9I78_RS09720	COG3604	Transcriptional regulator
C9I78_RS09725	COG1151	hydroxylamine reductase activity
C9I78_RS09730	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C9I78_RS09740	COG0564	pseudouridine synthase activity
C9I78_RS09750	COG0733	neurotransmitter:sodium symporter activity
C9I78_RS09760	COG0626	cystathionine gamma-synthase activity
C9I78_RS09765	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
C9I78_RS09770	COG5380	lipid catabolic process
C9I78_RS09775	COG2818	Glycosylase
C9I78_RS09790	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C9I78_RS09795	COG1983	PspC domain protein
C9I78_RS09805	COG1842	Phage shock protein A
C9I78_RS09810	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
C9I78_RS09825	COG4171	peptide transport system, permease
C9I78_RS09835	COG4172	Belongs to the ABC transporter superfamily
C9I78_RS09845	COG1227	inorganic diphosphatase activity
C9I78_RS09860	COG0243	molybdopterin cofactor binding
C9I78_RS09865	COG3005	denitrification pathway
C9I78_RS09870	COG4459	periplasmic nitrate reductase
C9I78_RS09875	COG0390	transport system, permease component
C9I78_RS09885	COG2116	formate transmembrane transporter activity
C9I78_RS09910	COG1434	Gram-negative-bacterium-type cell wall biogenesis
C9I78_RS09915	COG1435	thymidine kinase activity
C9I78_RS09920	COG0215	cysteine-tRNA ligase activity
C9I78_RS09925	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C9I78_RS09930	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C9I78_RS09935	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
C9I78_RS09945	COG3012	SEC-C Motif Domain Protein
C9I78_RS09950	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
C9I78_RS09950	COG0140	phosphoribosyl-ATP diphosphatase activity
C9I78_RS09955	COG0107	imidazoleglycerol-phosphate synthase activity
C9I78_RS09960	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
C9I78_RS09965	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
C9I78_RS09970	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
C9I78_RS09970	COG0131	Imidazoleglycerol-phosphate dehydratase
C9I78_RS09975	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
C9I78_RS09980	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
C9I78_RS09985	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
C9I78_RS10000	COG1757	Na H antiporter
C9I78_RS10010	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C9I78_RS10020	COG0482	sulfurtransferase activity
C9I78_RS10025	COG2915	High frequency lysogenization protein hflD homolog
C9I78_RS10030	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
C9I78_RS10055	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
C9I78_RS10070	COG0300	oxidoreductase activity
C9I78_RS10080	COG0501	Belongs to the peptidase M48B family
C9I78_RS10090	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
C9I78_RS10100	COG0156	8-amino-7-oxononanoate synthase activity
C9I78_RS10105	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
C9I78_RS10110	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C9I78_RS10115	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C9I78_RS10130	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
C9I78_RS10135	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
C9I78_RS10140	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
C9I78_RS10145	COG1674	ftsk spoiiie
C9I78_RS10155	COG0686	Belongs to the AlaDH PNT family
C9I78_RS10165	COG0583	DNA-binding transcription factor activity
C9I78_RS10180	COG3568	Endonuclease Exonuclease Phosphatase
C9I78_RS10210	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C9I78_RS10215	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C9I78_RS10230	COG0840	transmembrane signaling receptor activity
C9I78_RS10285	COG0784	Response regulator, receiver
C9I78_RS10285	COG5002	protein histidine kinase activity
C9I78_RS10295	COG0754	glutathionylspermidine amidase activity
C9I78_RS10305	COG3766	membrane
C9I78_RS10315	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
C9I78_RS10320	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
C9I78_RS10325	COG2885	chlorophyll binding
C9I78_RS10330	COG0823	Involved in the tonB-independent uptake of proteins
C9I78_RS10345	COG0811	peptide transport
C9I78_RS10350	COG0824	Thioesterase
C9I78_RS10360	COG4890	Cyd operon protein YbgT
C9I78_RS10365	COG1294	oxidase, subunit
C9I78_RS10370	COG1271	oxidase subunit
C9I78_RS10375	COG2255	four-way junction helicase activity
C9I78_RS10380	COG0632	four-way junction helicase activity
C9I78_RS10385	COG0840	transmembrane signaling receptor activity
C9I78_RS10390	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
C9I78_RS10395	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
C9I78_RS10400	COG1801	Protein of unknown function DUF72
C9I78_RS10405	COG4106	trans-aconitate 2-methyltransferase activity
C9I78_RS10410	COG0500	methyltransferase
C9I78_RS10420	COG4067	protein conserved in archaea
C9I78_RS10420	COG0189	ligase activity
C9I78_RS10440	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
C9I78_RS10445	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
C9I78_RS10450	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
C9I78_RS10455	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C9I78_RS10460	COG1434	Gram-negative-bacterium-type cell wall biogenesis
C9I78_RS10465	COG0745	RESPONSE REGULATOR receiver
C9I78_RS10470	COG3381	protein complex oligomerization
C9I78_RS10475	COG1609	Transcriptional regulator
C9I78_RS10480	COG3070	regulator of competence-specific genes
C9I78_RS10500	COG0297	glycogen (starch) synthase activity
C9I78_RS10505	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
C9I78_RS10520	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
C9I78_RS10530	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
C9I78_RS10535	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
C9I78_RS10540	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
C9I78_RS10550	COG0542	response to heat
C9I78_RS10555	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
C9I78_RS10560	COG1278	Cold shock
C9I78_RS10570	COG1187	pseudouridine synthase activity
C9I78_RS10575	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
C9I78_RS10585	COG1199	ATP-dependent helicase activity
C9I78_RS10590	COG0730	response to heat
C9I78_RS10595	COG3923	Primosomal replication protein n
C9I78_RS10605	COG0708	Exodeoxyribonuclease III
C9I78_RS10650	COG1882	Formate acetyltransferase
C9I78_RS10660	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C9I78_RS10670	COG3013	Belongs to the UPF0304 family
C9I78_RS10680	COG2766	serine protein kinase
C9I78_RS10685	COG2718	Belongs to the UPF0229 family
C9I78_RS10690	COG2719	SpoVR family
C9I78_RS10695	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
C9I78_RS10705	COG1663	tetraacyldisaccharide 4'-kinase activity
C9I78_RS10710	COG1132	(ABC) transporter
C9I78_RS10715	COG0658	competence protein
C9I78_RS10715	COG2333	competence protein COMEC
C9I78_RS10725	COG4591	ABC-type transport system involved in lipoprotein release permease component
C9I78_RS10730	COG1136	(ABC) transporter
C9I78_RS10735	COG4591	ABC-type transport system involved in lipoprotein release permease component
C9I78_RS10745	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
C9I78_RS10760	COG1252	NADH dehydrogenase
C9I78_RS10770	COG3150	esterase
C9I78_RS10795	COG0537	adenosine 5'-monophosphoramidase activity
C9I78_RS10825	COG0516	GMP reductase activity
C9I78_RS10825	COG0517	IMP dehydrogenase activity
C9I78_RS10835	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
C9I78_RS10840	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
C9I78_RS10845	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C9I78_RS10855	COG2199	diguanylate cyclase activity
C9I78_RS10870	COG3126	Type III secretion system lipoprotein chaperone (YscW)
C9I78_RS10875	COG1946	Acyl-CoA thioesterase
C9I78_RS10885	COG1522	sequence-specific DNA binding
C9I78_RS10915	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C9I78_RS10965	COG0477	Major facilitator Superfamily
C9I78_RS10970	COG2855	membrane
C9I78_RS10990	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
C9I78_RS10995	COG0596	Alpha beta hydrolase
C9I78_RS11000	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
C9I78_RS11005	COG1169	isochorismate synthase
C9I78_RS11010	COG0436	Aminotransferase
C9I78_RS11015	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
C9I78_RS11020	COG0232	Belongs to the dGTPase family. Type 2 subfamily
C9I78_RS11035	COG1555	photosystem II stabilization
C9I78_RS11040	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C9I78_RS11045	COG0776	regulation of translation
C9I78_RS11050	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
C9I78_RS11055	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
C9I78_RS11065	COG0544	peptidyl-prolyl cis-trans isomerase activity
C9I78_RS11085	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
C9I78_RS11090	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
C9I78_RS11095	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
C9I78_RS11100	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
C9I78_RS11120	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C9I78_RS11125	COG0569	domain protein
C9I78_RS11130	COG0513	Belongs to the DEAD box helicase family
C9I78_RS11135	COG1253	flavin adenine dinucleotide binding
C9I78_RS11170	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C9I78_RS11175	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C9I78_RS11195	COG1216	Glycosyl transferase, family 2
C9I78_RS11200	COG2986	histidine ammonia-lyase
C9I78_RS11225	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C9I78_RS11235	COG1028	Short-chain dehydrogenase reductase Sdr
C9I78_RS11255	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
C9I78_RS11260	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C9I78_RS11265	COG0583	DNA-binding transcription factor activity
C9I78_RS11270	COG2951	lytic endotransglycosylase activity
C9I78_RS11275	COG3100	YcgL domain-containing protein
C9I78_RS11280	COG0850	regulation of cytokinetic process
C9I78_RS11285	COG2894	cell division
C9I78_RS11290	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
C9I78_RS11295	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
C9I78_RS11300	COG0318	PFAM AMP-dependent synthetase and ligase
C9I78_RS11305	COG2267	carboxylic ester hydrolase activity
C9I78_RS11320	COG1214	PFAM Peptidase M22, glycoprotease
C9I78_RS11325	COG1199	ATP-dependent helicase activity
C9I78_RS11330	COG0788	formyltetrahydrofolate deformylase activity
C9I78_RS11335	COG3102	Protein conserved in bacteria
C9I78_RS11345	COG0018	arginyl-trna synthetase
C9I78_RS11365	COG1918	ferrous iron import across plasma membrane
C9I78_RS11380	COG4977	sequence-specific DNA binding
C9I78_RS11385	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
C9I78_RS11390	COG1121	(ABC) transporter
C9I78_RS11395	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C9I78_RS11405	COG0045	succinate-CoA ligase (ADP-forming) activity
C9I78_RS11410	COG0508	dehydrogenase complex catalyzes the overall conversion of
C9I78_RS11415	COG0567	Dehydrogenase, E1 component
C9I78_RS11420	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C9I78_RS11425	COG1053	succinate dehydrogenase
C9I78_RS11430	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
C9I78_RS11445	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
C9I78_RS11455	COG0033	Phosphoglucomutase
C9I78_RS11460	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
C9I78_RS11465	COG0596	Alpha beta hydrolase
C9I78_RS11485	COG0735	belongs to the Fur family
C9I78_RS11490	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C9I78_RS11495	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C9I78_RS11495	COG1263	PTS System
C9I78_RS11505	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
C9I78_RS11510	COG1940	carbohydrate kinase activity
C9I78_RS11510	COG1846	Transcriptional regulator
C9I78_RS11515	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C9I78_RS11515	COG4651	solute:proton antiporter activity
C9I78_RS11520	COG0367	asparagine synthase
C9I78_RS11525	COG0250	Participates in transcription elongation, termination and antitermination
C9I78_RS11530	COG3104	oligopeptide transport
C9I78_RS11535	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
C9I78_RS11540	COG0563	adenylate kinase activity
C9I78_RS11545	COG0326	Molecular chaperone. Has ATPase activity
C9I78_RS11550	COG3710	Transcriptional regulator
C9I78_RS11570	COG0622	Phosphoesterase
C9I78_RS11600	COG1090	epimerase
C9I78_RS11605	COG0300	oxidoreductase activity
C9I78_RS11615	COG3118	belongs to the thioredoxin family
C9I78_RS11620	COG0330	HflC and HflK could
C9I78_RS11650	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
C9I78_RS11655	COG3115	cell septum assembly
C9I78_RS11660	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
C9I78_RS11665	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C9I78_RS11675	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C9I78_RS11680	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C9I78_RS11685	COG2190	(PTS) system
C9I78_RS11695	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C9I78_RS11700	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C9I78_RS11710	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C9I78_RS11720	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C9I78_RS11730	COG1705	Flagellar rod assembly protein muramidase FlgJ
C9I78_RS11730	COG3951	Flagellar rod assembly protein muramidase FlgJ
C9I78_RS11735	COG1706	bacterial-type flagellum-dependent cell motility
C9I78_RS11740	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
C9I78_RS11750	COG4787	bacterial-type flagellum-dependent cell motility
C9I78_RS11760	COG1749	Flagellar hook protein flgE
C9I78_RS11770	COG1558	bacterial-type flagellum-dependent cell motility
C9I78_RS11775	COG1815	bacterial-type flagellum-dependent cell motility
C9I78_RS11780	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
C9I78_RS11785	COG0835	chemotaxis
C9I78_RS11785	COG0784	Response regulator, receiver
C9I78_RS11845	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C9I78_RS11850	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
C9I78_RS11865	COG2608	mercury ion transmembrane transporter activity
C9I78_RS11865	COG2217	Heavy metal translocating P-type atpase
C9I78_RS11905	COG2840	Smr protein MutS2
C9I78_RS11910	COG1187	pseudouridine synthase activity
C9I78_RS11920	COG0737	Belongs to the 5'-nucleotidase family
C9I78_RS11925	COG2877	3-deoxy-8-phosphooctulonate synthase activity
C9I78_RS11930	COG2912	Transglutaminase-like superfamily
C9I78_RS11935	COG3094	Invasion gene expression up-regulator, SirB
C9I78_RS11940	COG2890	protein-(glutamine-N5) methyltransferase activity
C9I78_RS11945	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
C9I78_RS11950	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
C9I78_RS11955	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
C9I78_RS11960	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
C9I78_RS11965	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
C9I78_RS11970	COG0193	aminoacyl-tRNA hydrolase activity
C9I78_RS11975	COG0012	GTP binding
C9I78_RS12090	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C9I78_RS12100	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
C9I78_RS12105	COG1702	phosphate starvation-inducible protein PhoH
C9I78_RS12110	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
C9I78_RS12115	COG4535	Mg2 and Co2 transporter CorC
C9I78_RS12120	COG0815	Transfers the fatty acyl group on membrane lipoproteins
C9I78_RS12125	COG2888	peptidyl-tyrosine sulfation
C9I78_RS12130	COG0495	leucyl-tRNA aminoacylation
C9I78_RS12135	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
C9I78_RS12140	COG1466	dna polymerase III delta subunit
C9I78_RS12145	COG0799	negative regulation of ribosome biogenesis
C9I78_RS12150	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
C9I78_RS12155	COG0768	penicillin binding
C9I78_RS12160	COG0772	Belongs to the SEDS family
C9I78_RS12165	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
C9I78_RS12170	COG1686	Belongs to the peptidase S11 family
C9I78_RS12175	COG2921	Belongs to the UPF0250 family
C9I78_RS12180	COG0321	lipoyl(octanoyl) transferase activity
C9I78_RS12185	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
C9I78_RS12190	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
C9I78_RS12195	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C9I78_RS12210	COG0366	Alpha amylase catalytic
C9I78_RS12215	COG1263	PTS System
C9I78_RS12215	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C9I78_RS12225	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
C9I78_RS12235	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C9I78_RS12240	COG2011	ABC-type metal ion transport system permease component
C9I78_RS12245	COG1464	Belongs to the NlpA lipoprotein family
C9I78_RS12250	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
C9I78_RS12260	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
C9I78_RS12260	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
C9I78_RS12275	COG1611	Belongs to the LOG family
C9I78_RS12280	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C9I78_RS12290	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
C9I78_RS12295	COG2363	Small membrane protein
C9I78_RS12305	COG0583	DNA-binding transcription factor activity
C9I78_RS12310	COG0301	tRNA thio-modification
C9I78_RS12310	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C9I78_RS12315	COG2885	chlorophyll binding
C9I78_RS12320	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
C9I78_RS12325	COG1722	exodeoxyribonuclease VII activity
C9I78_RS12330	COG0142	geranyltranstransferase activity
C9I78_RS12335	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
C9I78_RS12340	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
C9I78_RS12345	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
C9I78_RS12350	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C9I78_RS12370	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C9I78_RS12370	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C9I78_RS12375	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
C9I78_RS12380	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
C9I78_RS12385	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
C9I78_RS12395	COG1073	alpha beta
C9I78_RS12400	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
C9I78_RS12405	COG2252	PERMEase
C9I78_RS12410	COG2195	Cleaves the N-terminal amino acid of tripeptides
C9I78_RS12435	COG0047	phosphoribosylformylglycinamidine synthase activity
C9I78_RS12435	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C9I78_RS12440	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
C9I78_RS12455	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
C9I78_RS12495	COG0484	heat shock protein binding
C9I78_RS12500	COG0443	Heat shock 70 kDa protein
C9I78_RS12510	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
C9I78_RS12515	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
C9I78_RS12525	COG0497	DNA recombination
C9I78_RS12530	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C9I78_RS12535	COG2914	Belongs to the UPF0125 (RnfH) family
C9I78_RS12540	COG2867	negative regulation of translational initiation
C9I78_RS12545	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
C9I78_RS12555	COG0582	viral genome integration into host DNA
C9I78_RS12615	COG0732	type I restriction modification DNA specificity domain
C9I78_RS12705	COG0583	DNA-binding transcription factor activity
C9I78_RS12710	COG3153	acetyltransferase
C9I78_RS12710	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C9I78_RS12730	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C9I78_RS12735	COG2873	o-acetylhomoserine
C9I78_RS12770	COG1115	amino acid carrier protein
C9I78_RS12780	COG1584	GPR1 FUN34 yaaH family protein
C9I78_RS12790	COG1757	Na H antiporter
C9I78_RS12870	COG0582	viral genome integration into host DNA
C9I78_RS12875	COG0518	GMP synthase (glutamine-hydrolyzing) activity
C9I78_RS12875	COG0519	Catalyzes the synthesis of GMP from XMP
C9I78_RS12880	COG0517	IMP dehydrogenase activity
C9I78_RS12880	COG0516	GMP reductase activity
C9I78_RS12885	COG1570	exodeoxyribonuclease VII activity
C9I78_RS12900	COG1160	GTP binding
C9I78_RS12905	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C9I78_RS12910	COG2976	Protein conserved in bacteria
C9I78_RS12915	COG0124	histidyl-tRNA synthetase
C9I78_RS12920	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
C9I78_RS12935	COG0820	rRNA (adenine-C2-)-methyltransferase activity
C9I78_RS12940	COG0105	UTP biosynthetic process
C9I78_RS12945	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
C9I78_RS12950	COG2975	iron-sulfur cluster assembly
C9I78_RS12955	COG0633	Ferredoxin
C9I78_RS12960	COG0443	Heat shock 70 kDa protein
C9I78_RS12965	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
C9I78_RS12975	COG0822	iron-sulfur transferase activity
C9I78_RS12980	COG1104	cysteine desulfurase activity
C9I78_RS12985	COG1959	2 iron, 2 sulfur cluster binding
C9I78_RS12995	COG0483	inositol monophosphate 1-phosphatase activity
C9I78_RS13005	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C9I78_RS13010	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C9I78_RS13015	COG1862	Preprotein translocase
C9I78_RS13020	COG0343	queuine tRNA-ribosyltransferase activity
C9I78_RS13025	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
C9I78_RS13040	COG0517	IMP dehydrogenase activity
C9I78_RS13050	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
C9I78_RS13060	COG0583	DNA-binding transcription factor activity
C9I78_RS13065	COG0450	alkyl hydroperoxide reductase
C9I78_RS13075	COG3142	Participates in the control of copper homeostasis
C9I78_RS13085	COG0704	Plays a role in the regulation of phosphate uptake
C9I78_RS13090	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C9I78_RS13095	COG0581	inorganic phosphate transmembrane transporter activity
C9I78_RS13105	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
C9I78_RS13110	COG0248	Ppx GppA phosphatase
C9I78_RS13120	COG5002	protein histidine kinase activity
C9I78_RS13125	COG0745	RESPONSE REGULATOR receiver
C9I78_RS13135	COG2974	May be involved in recombination
C9I78_RS13140	COG0826	peptidase U32
C9I78_RS13145	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
C9I78_RS13205	COG0542	response to heat
C9I78_RS13215	COG0564	pseudouridine synthase activity
C9I78_RS13220	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C9I78_RS13225	COG0741	lytic transglycosylase activity
C9I78_RS13230	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
C9I78_RS13235	COG0077	Prephenate dehydratase
C9I78_RS13235	COG1605	Chorismate mutase
C9I78_RS13240	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
C9I78_RS13245	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
C9I78_RS13255	COG0488	(ABC) transporter
C9I78_RS13270	COG0739	heme binding
C9I78_RS13275	COG0287	Prephenate dehydrogenase
C9I78_RS13275	COG1605	Chorismate mutase
C9I78_RS13280	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C9I78_RS13285	COG1472	Belongs to the glycosyl hydrolase 3 family
C9I78_RS13290	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
C9I78_RS13295	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
C9I78_RS13310	COG1966	Carbon starvation protein
C9I78_RS13315	COG3275	phosphorelay sensor kinase activity
C9I78_RS13320	COG3279	Response regulator of the LytR AlgR family
C9I78_RS13325	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
C9I78_RS13330	COG1047	Peptidyl-prolyl cis-trans
C9I78_RS13335	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
C9I78_RS13340	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
C9I78_RS13345	COG0196	riboflavin kinase activity
C9I78_RS13350	COG0728	peptidoglycan biosynthetic process
C9I78_RS13355	COG0268	Binds directly to 16S ribosomal RNA
C9I78_RS13365	COG0640	Transcriptional regulator
C9I78_RS13375	COG0583	DNA-binding transcription factor activity
C9I78_RS13380	COG1283	sodium-dependent phosphate transmembrane transporter activity
C9I78_RS13390	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
C9I78_RS13395	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
C9I78_RS13400	COG0730	response to heat
C9I78_RS13410	COG0494	nUDIX hydrolase
C9I78_RS13420	COG3066	DNA modification
C9I78_RS13430	COG0667	Aldo Keto reductase
C9I78_RS13445	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
C9I78_RS13455	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
C9I78_RS13460	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C9I78_RS13465	COG4974	Belongs to the 'phage' integrase family
C9I78_RS13470	COG0716	FMN binding
C9I78_RS13480	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
C9I78_RS13485	COG0513	Belongs to the DEAD box helicase family
C9I78_RS13490	COG3022	response to hydroperoxide
C9I78_RS13495	COG1115	amino acid carrier protein
C9I78_RS13510	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
C9I78_RS13520	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
C9I78_RS13525	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
C9I78_RS13530	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
C9I78_RS13580	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
C9I78_RS13585	COG0083	homoserine kinase activity
C9I78_RS13600	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
C9I78_RS13615	COG0745	RESPONSE REGULATOR receiver
C9I78_RS13625	COG0784	Response regulator, receiver
C9I78_RS13625	COG2198	Histidine kinase
C9I78_RS13625	COG5002	protein histidine kinase activity
C9I78_RS13630	COG5001	Diguanylate cyclase
C9I78_RS13630	COG4251	negative regulation of phosphorylation
C9I78_RS13630	COG2203	Gaf domain
C9I78_RS13630	COG3706	GGDEF domain
C9I78_RS13635	COG1242	4 iron, 4 sulfur cluster binding
C9I78_RS13640	COG0069	glutamate synthase activity
C9I78_RS13640	COG0070	glutamate synthase
C9I78_RS13640	COG0067	glutamate synthase
C9I78_RS13650	COG0070	glutamate synthase
C9I78_RS13650	COG0069	glutamate synthase activity
C9I78_RS13650	COG0067	glutamate synthase
C9I78_RS13655	COG0493	'glutamate synthase
C9I78_RS13665	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
C9I78_RS13675	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C9I78_RS13680	COG2860	membrane
C9I78_RS13685	COG0583	DNA-binding transcription factor activity
C9I78_RS13690	COG0730	response to heat
C9I78_RS13705	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C9I78_RS13710	COG0505	Belongs to the CarA family
C9I78_RS13715	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
C9I78_RS13720	COG0494	nUDIX hydrolase
C9I78_RS13725	COG0653	protein targeting
C9I78_RS13735	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
C9I78_RS13740	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
C9I78_RS13745	COG0849	cell division
C9I78_RS13750	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
C9I78_RS13755	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
C9I78_RS13760	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
C9I78_RS13765	COG0772	Belongs to the SEDS family
C9I78_RS13770	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
C9I78_RS13775	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C9I78_RS13780	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C9I78_RS13785	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
C9I78_RS13790	COG0768	penicillin binding
C9I78_RS13795	COG3116	cell division
C9I78_RS13800	COG0275	rRNA processing
C9I78_RS13815	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
C9I78_RS13825	COG0792	nuclease activity
C9I78_RS13830	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
C9I78_RS13835	COG2823	Periplasmic or secreted lipoprotein
C9I78_RS13840	COG2969	positive regulation of protein catabolic process
C9I78_RS13845	COG0625	glutathione transferase activity
C9I78_RS13850	COG2857	Cytochrome c1
C9I78_RS13855	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
C9I78_RS13860	COG0723	plastoquinol--plastocyanin reductase activity
C9I78_RS13865	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
C9I78_RS13870	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
C9I78_RS13880	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
C9I78_RS13890	COG3105	Protein conserved in bacteria
C9I78_RS13900	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C9I78_RS13915	COG3150	esterase
C9I78_RS13925	COG3151	Protein conserved in bacteria
C9I78_RS13930	COG0494	nUDIX hydrolase
C9I78_RS13935	COG1538	Outer membrane efflux protein
C9I78_RS13940	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
C9I78_RS13940	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
C9I78_RS13945	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
C9I78_RS13960	COG3025	triphosphatase activity
C9I78_RS13965	COG1392	Phosphate transport regulator
C9I78_RS13970	COG0306	phosphate transporter
C9I78_RS13975	COG4991	sh3 domain protein
C9I78_RS13985	COG3409	Peptidoglycan-binding domain 1 protein
C9I78_RS13985	COG3267	Type II secretory pathway component ExeA
C9I78_RS13990	COG0617	tRNA 3'-terminal CCA addition
C9I78_RS13995	COG1968	undecaprenyl-diphosphatase activity
C9I78_RS14000	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C9I78_RS14005	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
C9I78_RS14010	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
C9I78_RS14015	COG0596	Alpha beta hydrolase
C9I78_RS14020	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
C9I78_RS14025	COG0828	Belongs to the bacterial ribosomal protein bS21 family
C9I78_RS14030	COG1610	YqeY-like protein
C9I78_RS14035	COG0358	DNA primase activity
C9I78_RS14085	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C9I78_RS14095	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C9I78_RS14110	COG3550	peptidyl-serine autophosphorylation
C9I78_RS14120	COG5001	Diguanylate cyclase
C9I78_RS14120	COG3300	MHYT domain
C9I78_RS14170	COG0732	type I restriction modification DNA specificity domain
C9I78_RS14195	COG2264	protein methyltransferase activity
C9I78_RS14205	COG1162	GTPase activity
C9I78_RS14215	COG3706	GGDEF domain
C9I78_RS14250	COG1464	Belongs to the NlpA lipoprotein family
C9I78_RS14260	COG2207	Transcriptional regulator
C9I78_RS14295	COG2213	PTS system mannitol-specific
C9I78_RS14295	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
C9I78_RS14300	COG0246	Mannitol dehydrogenase
C9I78_RS14305	COG3722	fumarate hydratase activity
C9I78_RS14320	COG1461	Dihydroxyacetone kinase
C9I78_RS14325	COG2376	Dihydroxyacetone kinase
C9I78_RS14335	COG5002	protein histidine kinase activity
C9I78_RS14350	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
C9I78_RS14355	COG1349	DNA-binding transcription factor activity
C9I78_RS14365	COG0469	pyruvate kinase activity
C9I78_RS14380	COG0440	acetolactate synthase activity
C9I78_RS14385	COG0028	Belongs to the TPP enzyme family
C9I78_RS14390	COG1022	Amp-dependent synthetase and ligase
C9I78_RS14395	COG0583	DNA-binding transcription factor activity
C9I78_RS14415	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C9I78_RS14420	COG0473	3-isopropylmalate dehydrogenase activity
C9I78_RS14425	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
C9I78_RS14430	COG0066	3-isopropylmalate dehydratase activity
C9I78_RS14440	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
C9I78_RS14445	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
C9I78_RS14450	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C9I78_RS14455	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
C9I78_RS14460	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
C9I78_RS14465	COG2967	ApaG domain
C9I78_RS14470	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
C9I78_RS14485	COG2966	Psort location CytoplasmicMembrane, score
C9I78_RS14490	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
C9I78_RS14500	COG0261	This protein binds to 23S rRNA in the presence of protein L20
C9I78_RS14505	COG0142	geranyltranstransferase activity
C9I78_RS14515	COG0039	L-malate dehydrogenase activity
C9I78_RS14530	COG2358	TRAP transporter, solute receptor (TAXI family
C9I78_RS14550	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
C9I78_RS14555	COG1178	ABC-type Fe3 transport system permease component
C9I78_RS14560	COG4143	(ABC) transporter
C9I78_RS14565	COG0163	prenyltransferase activity
C9I78_RS14570	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
C9I78_RS14580	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
C9I78_RS14585	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
C9I78_RS14595	COG2105	PFAM AIG2 family protein
C9I78_RS14605	COG0729	surface antigen
C9I78_RS14610	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C9I78_RS14620	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
C9I78_RS14635	COG4181	ATPase activity
C9I78_RS14655	COG0529	Catalyzes the synthesis of activated sulfate
C9I78_RS14660	COG3273	potassium ion transport
C9I78_RS14660	COG0471	metal ion transport
C9I78_RS14670	COG2895	sulfate adenylyltransferase (ATP) activity
C9I78_RS14675	COG0175	sulfate reduction
C9I78_RS14680	COG1648	precorrin-2 dehydrogenase activity
C9I78_RS14680	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
C9I78_RS14685	COG0737	Belongs to the 5'-nucleotidase family
C9I78_RS14695	COG0513	Belongs to the DEAD box helicase family
C9I78_RS14700	COG2153	protein acetylation
C9I78_RS14710	COG0545	Peptidyl-prolyl cis-trans isomerase
C9I78_RS14720	COG0203	ribosomal protein L17
C9I78_RS14725	COG0202	RNA polymerase activity
C9I78_RS14735	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
C9I78_RS14740	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
C9I78_RS14745	COG0257	Belongs to the bacterial ribosomal protein bL36 family
C9I78_RS14750	COG0201	protein transport
C9I78_RS14755	COG0200	Binds to the 23S rRNA
C9I78_RS14760	COG1841	ribosomal large subunit assembly
C9I78_RS14775	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
C9I78_RS14780	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
C9I78_RS14785	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
C9I78_RS14790	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
C9I78_RS14795	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
C9I78_RS14800	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
C9I78_RS14805	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
C9I78_RS14810	COG0255	Belongs to the universal ribosomal protein uL29 family
C9I78_RS14820	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
C9I78_RS14825	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
C9I78_RS14830	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
C9I78_RS14835	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
C9I78_RS14845	COG0088	Forms part of the polypeptide exit tunnel
C9I78_RS14850	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
C9I78_RS14860	COG0254	rRNA binding
C9I78_RS14870	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C9I78_RS14875	COG1609	Transcriptional regulator
C9I78_RS14885	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
C9I78_RS14890	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
C9I78_RS14895	COG1575	Belongs to the MenA family. Type 1 subfamily
C9I78_RS14900	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
C9I78_RS14905	COG3074	FtsZ-dependent cytokinesis
C9I78_RS14915	COG1494	fructose-1,6-bisphosphatase
C9I78_RS14940	COG0149	triose-phosphate isomerase activity
C9I78_RS14945	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
C9I78_RS14960	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
C9I78_RS14965	COG1215	transferase activity, transferring glycosyl groups
C9I78_RS14975	COG0438	transferase activity, transferring glycosyl groups
C9I78_RS14980	COG0463	Glycosyl transferase, family 2
C9I78_RS14980	COG1216	Glycosyl transferase, family 2
C9I78_RS15000	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
C9I78_RS15030	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C9I78_RS15040	COG1560	Kdo2-lipid A biosynthetic process
C9I78_RS15050	COG0859	PFAM glycosyl transferase family 9
C9I78_RS15055	COG1519	Transferase
C9I78_RS15070	COG0367	asparagine synthase
C9I78_RS15085	COG0728	peptidoglycan biosynthetic process
C9I78_RS15095	COG1083	cytidylyl-transferase
C9I78_RS15100	COG3642	lipopolysaccharide core region biosynthetic process
C9I78_RS15105	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
C9I78_RS15110	COG0859	PFAM glycosyl transferase family 9
C9I78_RS15115	COG0463	Glycosyl transferase, family 2
C9I78_RS15130	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
C9I78_RS15135	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
C9I78_RS15145	COG2194	sulfuric ester hydrolase activity
C9I78_RS15155	COG0227	Belongs to the bacterial ribosomal protein bL28 family
C9I78_RS15160	COG2003	Belongs to the UPF0758 family
C9I78_RS15175	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C9I78_RS15180	COG1309	transcriptional regulator
C9I78_RS15185	COG1560	Kdo2-lipid A biosynthetic process
C9I78_RS15190	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
C9I78_RS15195	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
C9I78_RS15205	COG1561	YicC-like family, N-terminal region
C9I78_RS15280	COG1061	Type III restriction enzyme res subunit
C9I78_RS15340	COG4608	Belongs to the ABC transporter superfamily
C9I78_RS15345	COG0444	Belongs to the ABC transporter superfamily
C9I78_RS15350	COG0747	negative chemotaxis
C9I78_RS15360	COG4174	ABC transporter (Permease)
C9I78_RS15385	COG0811	peptide transport
C9I78_RS15390	COG0848	biopolymer transport protein
C9I78_RS15405	COG0194	GDP metabolic process
C9I78_RS15410	COG1758	RNA polymerase activity
C9I78_RS15415	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C9I78_RS15420	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C9I78_RS15425	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
C9I78_RS15435	COG2233	PERMEase
C9I78_RS15455	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C9I78_RS15465	COG2183	response to ionizing radiation
C9I78_RS15475	COG0596	Alpha beta hydrolase
C9I78_RS15480	COG1040	competence protein
C9I78_RS15485	COG0316	Belongs to the HesB IscA family
C9I78_RS15485	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
C9I78_RS15490	COG0494	nUDIX hydrolase
C9I78_RS15495	COG1218	3'(2'),5'-bisphosphate nucleotidase
C9I78_RS15505	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
C9I78_RS15510	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
C9I78_RS15515	COG3156	type II secretion system protein K
C9I78_RS15520	COG4795	General secretion pathway protein
C9I78_RS15525	COG2165	general secretion pathway protein
C9I78_RS15530	COG2165	general secretion pathway protein
C9I78_RS15535	COG2165	general secretion pathway protein
C9I78_RS15540	COG1459	type II secretion system
C9I78_RS15545	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C9I78_RS15555	COG3031	protein transport across the cell outer membrane
C9I78_RS15560	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
C9I78_RS15565	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
C9I78_RS15570	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
C9I78_RS15580	COG0456	acetyltransferase
C9I78_RS15585	COG1490	D-aminoacyl-tRNA deacylase activity
C9I78_RS15590	COG1295	ribonuclease BN
C9I78_RS15605	COG1217	gtp-binding protein TYPA
C9I78_RS15610	COG0174	glutamine synthetase
C9I78_RS15620	COG3852	Histidine kinase
C9I78_RS15625	COG2204	response regulator
C9I78_RS15635	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
C9I78_RS15675	COG0218	Necessary for normal cell division and for the maintenance of normal septation
C9I78_RS15685	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C9I78_RS15685	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C9I78_RS15710	COG0084	hydrolase, TatD family'
C9I78_RS15720	COG0805	protein transport
C9I78_RS15725	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C9I78_RS15730	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C9I78_RS15735	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
C9I78_RS15740	COG3165	ubiquinone biosynthetic process from chorismate
C9I78_RS15745	COG2226	methyltransferase
C9I78_RS15750	COG1322	Protein conserved in bacteria
C9I78_RS15765	COG0628	permease
C9I78_RS15795	COG1597	lipid kinase activity
C9I78_RS15815	COG2823	Periplasmic or secreted lipoprotein
C9I78_RS15825	COG2081	HI0933 family
C9I78_RS15835	COG1528	Iron-storage protein
C9I78_RS15840	COG0589	response to stress
C9I78_RS15855	COG0742	ribosomal rna small subunit methyltransferase
C9I78_RS15860	COG5001	Diguanylate cyclase
C9I78_RS15860	COG5002	protein histidine kinase activity
C9I78_RS15865	COG1522	sequence-specific DNA binding
C9I78_RS15870	COG0339	signal peptide processing
C9I78_RS15880	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
C9I78_RS15885	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C9I78_RS15890	COG0583	DNA-binding transcription factor activity
C9I78_RS15895	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
C9I78_RS15900	COG0800	Aldolase
C9I78_RS15905	COG2610	gluconate transmembrane transporter activity
C9I78_RS15910	COG3265	gluconokinase activity
C9I78_RS15915	COG0129	dihydroxy-acid dehydratase activity
C9I78_RS15930	COG0583	DNA-binding transcription factor activity
C9I78_RS15935	COG1609	Transcriptional regulator
C9I78_RS15975	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C9I78_RS15980	COG0601	transmembrane transport
C9I78_RS15985	COG0747	negative chemotaxis
C9I78_RS15990	COG4172	Belongs to the ABC transporter superfamily
C9I78_RS16055	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C9I78_RS16060	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C9I78_RS16070	COG2960	long-chain fatty acid transporting porin activity
C9I78_RS16075	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
C9I78_RS16080	COG0583	DNA-binding transcription factor activity
C9I78_RS16130	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C9I78_RS16135	COG1739	Uncharacterized protein family UPF0029
C9I78_RS16140	COG1024	Enoyl-CoA hydratase
C9I78_RS16140	COG1250	3-hydroxyacyl-CoA dehydrogenase
C9I78_RS16145	COG0183	Belongs to the thiolase family
C9I78_RS16150	COG0604	alcohol dehydrogenase
C9I78_RS16165	COG0425	Belongs to the sulfur carrier protein TusA family
C9I78_RS16175	COG2119	membrane
C9I78_RS16180	COG0752	glycyl-tRNA synthetase alpha subunit
C9I78_RS16185	COG0751	glycine-tRNA ligase activity
C9I78_RS16190	COG0366	Alpha amylase catalytic
C9I78_RS16195	COG3977	Valine--pyruvate aminotransferase
C9I78_RS16200	COG0071	Belongs to the small heat shock protein (HSP20) family
C9I78_RS16220	COG0187	DNA topoisomerase II activity
C9I78_RS16225	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
C9I78_RS16230	COG0592	DNA-directed DNA polymerase activity
C9I78_RS16235	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
C9I78_RS16255	COG1126	abc transporter atp-binding protein
C9I78_RS16265	COG0594	ribonuclease P activity
C9I78_RS16275	COG0706	membrane insertase activity
C9I78_RS16280	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
C9I78_RS16285	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
C9I78_RS16290	COG0445	tRNA wobble uridine modification
C9I78_RS16295	COG0357	Ribosomal RNA small subunit methyltransferase G
C9I78_RS16300	COG1192	Involved in chromosome partitioning
C9I78_RS16305	COG1475	DNA binding
C9I78_RS16310	COG3312	ion transport
C9I78_RS16315	COG0356	it plays a direct role in the translocation of protons across the membrane
C9I78_RS16330	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
C9I78_RS16335	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
C9I78_RS16340	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
C9I78_RS16345	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
C9I78_RS16350	COG0355	proton-transporting ATP synthase activity, rotational mechanism
C9I78_RS16355	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
C9I78_RS16360	COG0765	amino acid transport
C9I78_RS16365	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C9I78_RS16370	COG2814	Major facilitator Superfamily
C9I78_RS16375	COG0583	DNA-binding transcription factor activity
C9I78_RS16385	COG0129	dihydroxy-acid dehydratase activity
C9I78_RS16390	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C9I78_RS16395	COG3978	acetolactate synthase activity
C9I78_RS16405	COG0606	chelatase, subunit chli
C9I78_RS16415	COG0204	Acyl-transferase
C9I78_RS16420	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C9I78_RS16425	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C9I78_RS16435	COG3084	Protein conserved in bacteria
C9I78_RS16445	COG4326	sporulation control protein
C9I78_RS16450	COG1272	protein, Hemolysin III
C9I78_RS16460	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C9I78_RS16465	COG0569	domain protein
C9I78_RS16470	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
C9I78_RS16470	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C9I78_RS16475	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
C9I78_RS16480	COG0242	peptide deformylase activity
C9I78_RS16490	COG0758	DNA mediated transformation
C9I78_RS16495	COG2922	Belongs to the Smg family
C9I78_RS16500	COG0551	DNA topoisomerase type I activity
C9I78_RS16505	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
C9I78_RS16510	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
C9I78_RS16515	COG0009	L-threonylcarbamoyladenylate synthase
C9I78_RS16520	COG0408	coproporphyrinogen oxidase activity
C9I78_RS16525	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
C9I78_RS16535	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
C9I78_RS16605	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
C9I78_RS16610	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
C9I78_RS16615	COG0352	thiamine-phosphate diphosphorylase activity
C9I78_RS16620	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C9I78_RS16625	COG2104	thiamine diphosphate biosynthetic process
C9I78_RS16630	COG2022	thiamine diphosphate biosynthetic process
C9I78_RS16640	COG0006	proline dipeptidase activity
C9I78_RS16640	COG0006	proline dipeptidase activity
C9I78_RS16670	COG3220	belongs to the UPF0276 family
C9I78_RS16680	COG0210	DNA helicase
C9I78_RS16690	COG0405	Gamma-glutamyltransferase
C9I78_RS16695	COG1280	lysine exporter protein (LysE YggA)
C9I78_RS16705	COG2962	Rard protein
C9I78_RS16710	COG0514	ATP-dependent DNA helicase (RecQ)
C9I78_RS16725	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
C9I78_RS16730	COG0248	Ppx GppA phosphatase
C9I78_RS16735	COG0513	Belongs to the DEAD box helicase family
C9I78_RS16740	COG3118	belongs to the thioredoxin family
C9I78_RS16760	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
C9I78_RS16765	COG0633	Ferredoxin
C9I78_RS16820	COG3071	HemY protein
C9I78_RS16825	COG2959	enzyme of heme biosynthesis
C9I78_RS16830	COG1587	Uroporphyrinogen-III synthase
C9I78_RS16835	COG0181	hydroxymethylbilane synthase activity
C9I78_RS16840	COG3072	Adenylate cyclase
C9I78_RS16845	COG1965	Belongs to the frataxin family
C9I78_RS16855	COG0019	diaminopimelate decarboxylase activity
C9I78_RS16860	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
C9I78_RS16870	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
C9I78_RS16875	COG1011	Hydrolase
C9I78_RS16880	COG2200	EAL domain
C9I78_RS16880	COG2199	diguanylate cyclase activity
C9I78_RS16880	COG3287	FIST C domain
C9I78_RS16885	COG3148	PFAM DTW domain containing protein
C9I78_RS16900	COG0561	phosphatase activity
C9I78_RS16910	COG2267	carboxylic ester hydrolase activity
C9I78_RS16915	COG1280	lysine exporter protein (LysE YggA)
C9I78_RS16920	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
C9I78_RS16925	COG0640	Transcriptional regulator
C9I78_RS16930	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C9I78_RS16990	COG2095	MarC family integral membrane protein
C9I78_RS16995	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
C9I78_RS17010	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C9I78_RS17045	COG0742	ribosomal rna small subunit methyltransferase
C9I78_RS17050	COG0552	protein localization to endoplasmic reticulum
C9I78_RS17055	COG2884	Cell division ATP-binding protein ftsE
C9I78_RS17060	COG2177	Part of the ABC transporter FtsEX involved in
C9I78_RS17075	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C9I78_RS17080	COG0705	Rhomboid family
C9I78_RS17085	COG1580	Controls the rotational direction of flagella during chemotaxis
C9I78_RS17090	COG3161	chorismate lyase activity
C9I78_RS17095	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
C9I78_RS17100	COG2937	Belongs to the GPAT DAPAT family
C9I78_RS17115	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
C9I78_RS17120	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
C9I78_RS17125	COG0534	Mate efflux family protein
C9I78_RS17130	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C9I78_RS17145	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C9I78_RS17150	COG4206	TonB-dependent receptor
C9I78_RS17160	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
C9I78_RS17230	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C9I78_RS17240	COG0812	UDP-N-acetylmuramate dehydrogenase activity
C9I78_RS17295	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C9I78_RS17370	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
C9I78_RS17375	COG5001	Diguanylate cyclase
C9I78_RS17380	COG1869	D-ribose catabolic process
C9I78_RS17385	COG1129	ABC transporter
C9I78_RS17390	COG1172	Belongs to the binding-protein-dependent transport system permease family
C9I78_RS17395	COG1879	ABC-type sugar transport system periplasmic component
C9I78_RS17400	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C9I78_RS17405	COG1609	Transcriptional regulator
C9I78_RS17420	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
C9I78_RS17440	COG0745	RESPONSE REGULATOR receiver
C9I78_RS17455	COG1785	Belongs to the alkaline phosphatase family
C9I78_RS17485	COG0814	amino acid
C9I78_RS17495	COG0243	molybdopterin cofactor binding
C9I78_RS17500	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
C9I78_RS17500	COG1648	precorrin-2 dehydrogenase activity
C9I78_RS17520	COG3707	response regulator
C9I78_RS17530	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C9I78_RS17535	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C9I78_RS17540	COG1116	anion transmembrane transporter activity
C9I78_RS17545	COG2146	nitrite reductase [NAD(P)H] activity
C9I78_RS17545	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C9I78_RS17600	COG0515	serine threonine protein kinase
C9I78_RS17600	COG2815	serine threonine protein kinase
C9I78_RS17640	COG0631	protein serine/threonine phosphatase activity
C9I78_RS17710	COG0420	3'-5' exonuclease activity
C9I78_RS17715	COG0419	ATPase involved in DNA repair
C9I78_RS17735	COG3040	lipid binding
C9I78_RS17745	COG2814	Major facilitator Superfamily
C9I78_RS17755	COG1288	antiporter activity
C9I78_RS17770	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
C9I78_RS17785	COG2425	protein containing a von Willebrand factor type A (vWA) domain
C9I78_RS17805	COG0583	DNA-binding transcription factor activity
C9I78_RS17810	COG0277	FAD linked oxidase domain protein
C9I78_RS17830	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C9I78_RS17870	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
C9I78_RS17870	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C9I78_RS17920	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C9I78_RS17925	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C9I78_RS17935	COG2116	formate transmembrane transporter activity
C9I78_RS17955	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
C9I78_RS17990	COG0534	Mate efflux family protein
C9I78_RS17995	COG0745	RESPONSE REGULATOR receiver
C9I78_RS17995	COG3292	Two component regulator propeller
C9I78_RS17995	COG2205	protein histidine kinase activity
C9I78_RS18005	COG3118	belongs to the thioredoxin family
C9I78_RS18010	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C9I78_RS18035	COG2271	Major facilitator Superfamily
C9I78_RS18040	COG3851	Histidine kinase
C9I78_RS18045	COG2197	response regulator
C9I78_RS18055	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
C9I78_RS18060	COG0583	DNA-binding transcription factor activity
C9I78_RS18070	COG0243	molybdopterin cofactor binding
C9I78_RS18075	COG0446	pyridine nucleotide-disulphide oxidoreductase
C9I78_RS18120	COG3706	GGDEF domain
C9I78_RS18170	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C9I78_RS18175	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
C9I78_RS18215	COG4735	regulation of single-species biofilm formation
C9I78_RS18305	COG3550	peptidyl-serine autophosphorylation
C9I78_RS18340	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C9I78_RS18355	COG1328	CTP reductase activity
C9I78_RS18360	COG0602	queuosine metabolic process
C9I78_RS18365	COG0534	Mate efflux family protein
C9I78_RS18385	COG0189	ligase activity
C9I78_RS18385	COG4067	protein conserved in archaea
C9I78_RS18395	COG3111	PFAM Bacterial OB fold (BOF) protein
C9I78_RS18400	COG1492	cobalamin metabolic process
C9I78_RS18405	COG0725	ABC transporter, periplasmic molybdate-binding protein
C9I78_RS18410	COG4149	molybdate abc transporter
C9I78_RS18415	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
C9I78_RS18425	COG3706	GGDEF domain
C9I78_RS18425	COG2203	Gaf domain
C9I78_RS18425	COG5001	Diguanylate cyclase
C9I78_RS18425	COG4251	negative regulation of phosphorylation
C9I78_RS18450	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
C9I78_RS18455	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
C9I78_RS18480	COG3140	Belongs to the UPF0181 family
C9I78_RS18485	COG0589	response to stress
C9I78_RS18495	COG0583	DNA-binding transcription factor activity
C9I78_RS18510	COG0023	Translation Initiation Factor
C9I78_RS18520	COG1181	Belongs to the D-alanine--D-alanine ligase family
C9I78_RS18530	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C9I78_RS18530	COG1042	CoA-binding domain protein
C9I78_RS18530	COG0045	succinate-CoA ligase (ADP-forming) activity
C9I78_RS18535	COG0583	DNA-binding transcription factor activity
C9I78_RS18550	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C9I78_RS18555	COG3447	MASE1 domain protein
C9I78_RS18555	COG5001	Diguanylate cyclase
C9I78_RS18555	COG5002	protein histidine kinase activity
C9I78_RS18560	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
C9I78_RS18565	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
C9I78_RS18570	COG1984	allophanate hydrolase subunit 2
C9I78_RS18580	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
C9I78_RS18585	COG4181	ATPase activity
C9I78_RS18595	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
C9I78_RS18600	COG3300	MHYT domain
C9I78_RS18600	COG5001	Diguanylate cyclase
C9I78_RS18610	COG0484	heat shock protein binding
C9I78_RS18635	COG4533	DNA binding
C9I78_RS18645	COG2050	protein possibly involved in aromatic compounds catabolism
C9I78_RS18660	COG2067	long-chain fatty acid transport protein
C9I78_RS18665	COG2267	carboxylic ester hydrolase activity
C9I78_RS18680	COG0861	Integral membrane protein TerC family
C9I78_RS18685	COG0737	Belongs to the 5'-nucleotidase family
C9I78_RS18690	COG3593	DNA synthesis involved in DNA repair
C9I78_RS18700	COG0583	DNA-binding transcription factor activity
C9I78_RS18705	COG2116	formate transmembrane transporter activity
C9I78_RS18710	COG2353	YceI-like domain
C9I78_RS18715	COG3038	cytochrome b561
C9I78_RS18730	COG4943	cyclic-guanylate-specific phosphodiesterase activity
C9I78_RS18735	COG0513	Belongs to the DEAD box helicase family
C9I78_RS18740	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
C9I78_RS18750	COG0840	transmembrane signaling receptor activity
C9I78_RS18760	COG0546	phosphoglycolate phosphatase activity
C9I78_RS18770	COG0784	Response regulator, receiver
C9I78_RS18770	COG3437	response regulator, receiver
C9I78_RS18790	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C9I78_RS18795	COG2759	Belongs to the formate--tetrahydrofolate ligase family
C9I78_RS18800	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
C9I78_RS18815	COG2207	Transcriptional regulator
C9I78_RS18820	COG1979	alcohol dehydrogenase
C9I78_RS18845	COG2271	Major facilitator Superfamily
C9I78_RS18850	COG0469	pyruvate kinase activity
C9I78_RS18855	COG1126	abc transporter atp-binding protein
C9I78_RS18860	COG0765	amino acid transport
C9I78_RS18865	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C9I78_RS18870	COG0765	amino acid transport
C9I78_RS18875	COG2200	EAL domain
C9I78_RS18875	COG2203	Gaf domain
C9I78_RS18875	COG2199	diguanylate cyclase activity
C9I78_RS18895	COG1609	Transcriptional regulator
C9I78_RS18900	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
C9I78_RS18900	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C9I78_RS18905	COG1105	Belongs to the carbohydrate kinase PfkB family
C9I78_RS18910	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C9I78_RS18910	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C9I78_RS18910	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
C9I78_RS18950	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
C9I78_RS18955	COG0509	glycine decarboxylation via glycine cleavage system
C9I78_RS18960	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
C9I78_RS18960	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
C9I78_RS19000	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
C9I78_RS19005	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
C9I78_RS19010	COG0583	DNA-binding transcription factor activity
C9I78_RS19015	COG2176	DNA-directed DNA polymerase activity
C9I78_RS19060	COG0242	peptide deformylase activity
C9I78_RS19090	COG2239	Acts as a magnesium transporter
C9I78_RS19110	COG0346	lactoylglutathione lyase activity
C9I78_RS19115	COG1902	pentaerythritol trinitrate reductase activity
C9I78_RS19135	COG5642	Protein of unknown function (DUF2384)
C9I78_RS19140	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
C9I78_RS19160	COG4565	transcriptional regulatory protein
C9I78_RS19165	COG3290	protein histidine kinase activity
C9I78_RS19170	COG0471	metal ion transport
C9I78_RS19200	COG2076	Multidrug Resistance protein
C9I78_RS19215	COG0671	phosphoesterase, PA-phosphatase related
C9I78_RS19230	COG2962	Rard protein
C9I78_RS19250	COG0784	Response regulator, receiver
C9I78_RS19250	COG0835	chemotaxis
C9I78_RS19275	COG2197	response regulator
C9I78_RS19285	COG3706	GGDEF domain
C9I78_RS19290	COG2197	response regulator
C9I78_RS19295	COG3300	MHYT domain
C9I78_RS19295	COG5001	Diguanylate cyclase
C9I78_RS19370	COG4964	Belongs to the GSP D family
C9I78_RS19395	COG2207	Transcriptional regulator
C9I78_RS19415	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
C9I78_RS19445	COG3069	C4-dicarboxylate transmembrane transporter activity
C9I78_RS19450	COG1704	LemA family
C9I78_RS19455	COG0501	Belongs to the peptidase M48B family
C9I78_RS19485	COG0641	radical SAM
C9I78_RS19505	COG3111	PFAM Bacterial OB fold (BOF) protein
C9I78_RS19510	COG1597	lipid kinase activity
C9I78_RS19515	COG0583	DNA-binding transcription factor activity
C9I78_RS19520	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C9I78_RS19520	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C9I78_RS19550	COG0714	Associated with various cellular activities
C9I78_RS19555	COG0641	radical SAM
C9I78_RS19560	COG3119	arylsulfatase activity
C9I78_RS19575	COG3119	arylsulfatase activity
C9I78_RS19580	COG3119	arylsulfatase activity
C9I78_RS19585	COG0745	RESPONSE REGULATOR receiver
C9I78_RS19600	COG2198	Histidine kinase
C9I78_RS19600	COG2205	protein histidine kinase activity
C9I78_RS19600	COG0784	Response regulator, receiver
C9I78_RS19605	COG1879	ABC-type sugar transport system periplasmic component
C9I78_RS19610	COG1803	Methylglyoxal synthase
C9I78_RS19615	COG0210	DNA helicase
C9I78_RS19620	COG1289	transmembrane transporter activity
C9I78_RS19655	COG4206	TonB-dependent receptor
C9I78_RS19670	COG0789	Transcriptional regulator
C9I78_RS19675	COG4604	ABC transporter, ATP-binding protein
C9I78_RS19680	COG4605	iron ion homeostasis
C9I78_RS19685	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C9I78_RS19690	COG4607	ABC-type enterochelin transport system periplasmic component
C9I78_RS19715	COG2847	Copper chaperone PCu(A)C
C9I78_RS19720	COG0443	Heat shock 70 kDa protein
C9I78_RS19755	COG0625	glutathione transferase activity
C9I78_RS19770	COG4160	amino acid transport
C9I78_RS19775	COG4215	(ABC) transporter
C9I78_RS19780	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C9I78_RS19785	COG1126	abc transporter atp-binding protein
C9I78_RS19815	COG1902	pentaerythritol trinitrate reductase activity
C9I78_RS19820	COG0109	protoheme IX farnesyltransferase activity
C9I78_RS19825	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
C9I78_RS19830	COG1845	cytochrome c oxidase, subunit III
C9I78_RS19835	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C9I78_RS19840	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C9I78_RS19845	COG1028	Short-chain dehydrogenase reductase Sdr
C9I78_RS19855	COG1024	Enoyl-CoA hydratase
C9I78_RS19875	COG0183	Belongs to the thiolase family
C9I78_RS19885	COG1960	acyl-CoA dehydrogenase activity
C9I78_RS19890	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C9I78_RS19895	COG1024	Enoyl-CoA hydratase
C9I78_RS19905	COG5413	integral membrane protein
C9I78_RS19920	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
C9I78_RS19930	COG5001	Diguanylate cyclase
C9I78_RS19935	COG0513	Belongs to the DEAD box helicase family
C9I78_RS19940	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
C9I78_RS19955	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C9I78_RS19975	COG0840	transmembrane signaling receptor activity
C9I78_RS19980	COG1119	ATPase activity
C9I78_RS19985	COG2200	EAL domain
C9I78_RS20005	COG0513	Belongs to the DEAD box helicase family
C9I78_RS20010	COG0523	cobalamin synthesis protein
C9I78_RS20020	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
C9I78_RS20030	COG0133	tryptophan synthase activity
C9I78_RS20035	COG4628	conserved protein (DUF2132)
C9I78_RS20040	COG0513	Belongs to the DEAD box helicase family
C9I78_RS20045	COG3530	Putative quorum-sensing-regulated virulence factor
C9I78_RS20070	COG2154	pterin-4-alpha-carbinolamine dehydratase
C9I78_RS20075	COG3186	Phenylalanine-4-hydroxylase
C9I78_RS20080	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C9I78_RS20085	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C9I78_RS20120	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
C9I78_RS20125	COG1454	alcohol dehydrogenase
C9I78_RS20130	COG2133	pyrroloquinoline quinone binding
C9I78_RS20140	COG0783	Belongs to the Dps family
C9I78_RS20145	COG0840	transmembrane signaling receptor activity
C9I78_RS20155	COG0577	efflux transmembrane transporter activity
C9I78_RS20155	COG1136	(ABC) transporter
C9I78_RS20175	COG2199	diguanylate cyclase activity
C9I78_RS20190	COG3036	rescue of stalled ribosome
C9I78_RS20195	COG1278	Cold shock
C9I78_RS20230	COG0545	Peptidyl-prolyl cis-trans isomerase
C9I78_RS20235	COG0109	protoheme IX farnesyltransferase activity
C9I78_RS20240	COG1612	heme a metabolic process
C9I78_RS20265	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
C9I78_RS20275	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C9I78_RS20280	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C9I78_RS20290	COG1280	lysine exporter protein (LysE YggA)
C9I78_RS20295	COG2207	Transcriptional regulator
C9I78_RS20325	COG0697	spore germination
C9I78_RS20350	COG2814	Major facilitator Superfamily
C9I78_RS20355	COG0583	DNA-binding transcription factor activity
C9I78_RS20360	COG5001	Diguanylate cyclase
C9I78_RS20365	COG0739	heme binding
C9I78_RS20390	COG3314	Sporulation integral membrane protein YlbJ
C9I78_RS20405	COG0814	amino acid
C9I78_RS20425	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
C9I78_RS20430	COG1072	(Pantothenic acid kinase))
C9I78_RS20440	COG1063	alcohol dehydrogenase
C9I78_RS20445	COG2213	PTS system mannitol-specific
C9I78_RS20450	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C9I78_RS20470	COG0798	PFAM Bile acid sodium symporter
C9I78_RS20480	COG1881	PFAM PEBP family protein
C9I78_RS20490	COG2706	6-phosphogluconolactonase activity
C9I78_RS20505	COG0840	transmembrane signaling receptor activity
C9I78_RS20515	COG1131	(ABC) transporter
C9I78_RS20520	COG0842	Transport permease protein
C9I78_RS20535	COG3383	formate dehydrogenase (NAD+) activity
C9I78_RS20560	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C9I78_RS20590	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C9I78_RS20600	COG2067	long-chain fatty acid transport protein
C9I78_RS20610	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C9I78_RS20625	COG0488	(ABC) transporter
C9I78_RS20630	COG0589	response to stress
C9I78_RS20635	COG2249	NAD(P)H dehydrogenase (quinone) activity
C9I78_RS20655	COG0366	Alpha amylase catalytic
C9I78_RS20665	COG4934	collagen metabolic process
C9I78_RS20680	COG0583	DNA-binding transcription factor activity
C9I78_RS20690	COG0783	Belongs to the Dps family
C9I78_RS20695	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
C9I78_RS20720	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C9I78_RS20720	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
C9I78_RS20730	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C9I78_RS20740	COG0835	chemotaxis
C9I78_RS20740	COG0784	Response regulator, receiver
C9I78_RS20750	COG0748	coenzyme F420 binding
C9I78_RS20755	COG3721	Heme iron utilization protein
C9I78_RS20765	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
C9I78_RS20770	COG0811	peptide transport
C9I78_RS20775	COG0848	biopolymer transport protein
C9I78_RS20785	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C9I78_RS20790	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
C9I78_RS20835	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
C9I78_RS20840	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
C9I78_RS20845	COG3217	Mosc domain protein beta barrel domain protein
C9I78_RS20845	COG0633	Ferredoxin
C9I78_RS20845	COG3217	Mosc domain protein beta barrel domain protein
C9I78_RS20845	COG0633	Ferredoxin
C9I78_RS20855	COG0401	homolog of Blt101
C9I78_RS20865	COG0418	dihydroorotase activity
C9I78_RS20870	COG2354	Protein conserved in bacteria
C9I78_RS20900	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C9I78_RS20900	COG2207	Transcriptional regulator
C9I78_RS20905	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C9I78_RS20950	COG0513	Belongs to the DEAD box helicase family
C9I78_RS20960	COG0583	DNA-binding transcription factor activity
C9I78_RS20975	COG1902	pentaerythritol trinitrate reductase activity
C9I78_RS20980	COG1063	alcohol dehydrogenase
C9I78_RS20990	COG1028	Short-chain dehydrogenase reductase Sdr
C9I78_RS21005	COG3122	Protein conserved in bacteria
C9I78_RS21025	COG0583	DNA-binding transcription factor activity
C9I78_RS21030	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
C9I78_RS21035	COG0252	asparaginase activity
C9I78_RS21040	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
C9I78_RS21045	COG0574	Belongs to the PEP-utilizing enzyme family
C9I78_RS21045	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C9I78_RS21065	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
C9I78_RS21085	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C9I78_RS21105	COG3706	GGDEF domain
C9I78_RS21125	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C9I78_RS21155	COG3842	ATPase activity
C9I78_RS21200	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C9I78_RS21250	COG0583	DNA-binding transcription factor activity
C9I78_RS21260	COG4948	Mandelate Racemase Muconate Lactonizing
C9I78_RS21295	COG1342	Belongs to the UPF0251 family
C9I78_RS21305	COG3015	lipoprotein NlpE involved in copper resistance
C9I78_RS21315	COG3713	MltA-interacting MipA family protein
C9I78_RS21330	COG0583	DNA-binding transcription factor activity
C9I78_RS21355	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
C9I78_RS21365	COG1335	isochorismatase
C9I78_RS21375	COG0753	catalase activity
C9I78_RS21385	COG1349	DNA-binding transcription factor activity
C9I78_RS21390	COG0346	lactoylglutathione lyase activity
C9I78_RS21395	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C9I78_RS21395	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C9I78_RS21410	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C9I78_RS21415	COG3537	Alpha-1,2-mannosidase
C9I78_RS21420	COG3537	Alpha-1,2-mannosidase
C9I78_RS21430	COG3537	Alpha-1,2-mannosidase
C9I78_RS21435	COG3537	Alpha-1,2-mannosidase
C9I78_RS21440	COG2070	2-Nitropropane dioxygenase
C9I78_RS21445	COG0737	Belongs to the 5'-nucleotidase family
C9I78_RS21455	COG1309	transcriptional regulator
C9I78_RS21475	COG1280	lysine exporter protein (LysE YggA)
C9I78_RS21490	COG0459	protein refolding
C9I78_RS21495	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
C9I78_RS21500	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C9I78_RS21525	COG1304	FMN binding
C9I78_RS21545	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C9I78_RS21560	COG1706	bacterial-type flagellum-dependent cell motility
C9I78_RS21565	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
C9I78_RS21570	COG4786	Flagellar basal body rod
C9I78_RS21575	COG4787	bacterial-type flagellum-dependent cell motility
C9I78_RS21580	COG1749	Flagellar hook protein flgE
C9I78_RS21585	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
C9I78_RS21590	COG1558	bacterial-type flagellum-dependent cell motility
C9I78_RS21595	COG1815	bacterial-type flagellum-dependent cell motility
C9I78_RS21615	COG0741	lytic transglycosylase activity
C9I78_RS21620	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
C9I78_RS21640	COG1760	l-serine dehydratase
C9I78_RS21645	COG3104	oligopeptide transport
C9I78_RS21665	COG0583	DNA-binding transcription factor activity
C9I78_RS21680	COG2866	Carboxypeptidase
C9I78_RS21685	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C9I78_RS21695	COG2990	Protein conserved in bacteria
C9I78_RS21720	COG3842	ATPase activity
C9I78_RS21730	COG1840	ABC-type Fe3 transport system, periplasmic component
C9I78_RS21735	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
C9I78_RS21740	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C9I78_RS21745	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C9I78_RS21750	COG1609	Transcriptional regulator
C9I78_RS21780	COG3240	lipase activity
C9I78_RS21790	COG0577	efflux transmembrane transporter activity
C9I78_RS21790	COG1136	(ABC) transporter
C9I78_RS21795	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C9I78_RS21800	COG2067	long-chain fatty acid transport protein
C9I78_RS21810	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
C9I78_RS21825	COG1011	Hydrolase
C9I78_RS21865	COG0110	maltose O-acetyltransferase activity
C9I78_RS21870	COG1765	OsmC-like protein
C9I78_RS21875	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C9I78_RS21875	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C9I78_RS21890	COG3046	protein related to deoxyribodipyrimidine photolyase
C9I78_RS21895	COG0415	Belongs to the DNA photolyase family
C9I78_RS21900	COG3706	GGDEF domain
C9I78_RS21915	COG0840	transmembrane signaling receptor activity
C9I78_RS21920	COG3706	GGDEF domain
C9I78_RS21935	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C9I78_RS21955	COG3033	Beta-eliminating lyase
C9I78_RS21965	COG0579	oxidoreductase
C9I78_RS21990	COG1114	Component of the transport system for branched-chain amino acids
C9I78_RS21995	COG2199	diguanylate cyclase activity
C9I78_RS22005	COG4191	Histidine kinase
C9I78_RS22040	COG0583	DNA-binding transcription factor activity
C9I78_RS22050	COG0189	ligase activity
C9I78_RS22055	COG4067	protein conserved in archaea
C9I78_RS22055	COG0189	ligase activity
C9I78_RS22065	COG1166	arginine decarboxylase activity
C9I78_RS22070	COG0010	Belongs to the arginase family
C9I78_RS22075	COG2814	Major facilitator Superfamily
C9I78_RS22080	COG1770	oligopeptidase
C9I78_RS22095	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C9I78_RS22100	COG1121	(ABC) transporter
C9I78_RS22105	COG0803	Belongs to the bacterial solute-binding protein 9 family
C9I78_RS22145	COG0848	biopolymer transport protein
C9I78_RS22150	COG0811	peptide transport
C9I78_RS22155	COG0811	peptide transport
C9I78_RS22175	COG0745	RESPONSE REGULATOR receiver
C9I78_RS22180	COG0039	L-malate dehydrogenase activity
C9I78_RS22185	COG0584	glycerophosphoryl diester phosphodiesterase
C9I78_RS22195	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C9I78_RS22255	COG1901	pseudouridine methyltransferase
C9I78_RS22260	COG0312	modulator of DNA gyrase
C9I78_RS22275	COG0351	phosphomethylpyrimidine kinase
C9I78_RS22280	COG1116	anion transmembrane transporter activity
C9I78_RS22285	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C9I78_RS22290	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C9I78_RS22295	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
C9I78_RS22300	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
C9I78_RS22305	COG0352	thiamine-phosphate diphosphorylase activity
C9I78_RS22315	COG0243	molybdopterin cofactor binding
C9I78_RS22320	COG3005	denitrification pathway
C9I78_RS22330	COG1028	Short-chain dehydrogenase reductase Sdr
C9I78_RS22345	COG0456	acetyltransferase
C9I78_RS22365	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C9I78_RS22370	COG1929	Belongs to the glycerate kinase type-1 family
C9I78_RS22375	COG2610	gluconate transmembrane transporter activity
C9I78_RS22380	COG3835	regulator
C9I78_RS22405	COG0546	phosphoglycolate phosphatase activity
C9I78_RS22420	COG0583	DNA-binding transcription factor activity
C9I78_RS22430	COG0583	DNA-binding transcription factor activity
C9I78_RS22440	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
C9I78_RS22445	COG3408	Glycogen debranching enzyme
C9I78_RS22445	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
C9I78_RS22475	COG3047	cAMP biosynthetic process
C9I78_RS22480	COG1357	PFAM Pentapeptide repeats (8 copies)
C9I78_RS22510	COG2375	cellular response to nickel ion
C9I78_RS22515	COG0823	Involved in the tonB-independent uptake of proteins
C9I78_RS22520	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C9I78_RS22540	COG0800	Aldolase
C9I78_RS22545	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C9I78_RS22560	COG1917	Cupin 2, conserved barrel domain protein
C9I78_RS22570	COG1028	Short-chain dehydrogenase reductase Sdr
C9I78_RS22575	COG1414	Transcriptional regulator
C9I78_RS22590	COG0583	DNA-binding transcription factor activity
C9I78_RS22595	COG2162	N-hydroxyarylamine O-acetyltransferase activity
C9I78_RS22600	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
C9I78_RS22615	COG2199	diguanylate cyclase activity
C9I78_RS22625	COG0561	phosphatase activity
C9I78_RS22630	COG0583	DNA-binding transcription factor activity
C9I78_RS22645	COG0564	pseudouridine synthase activity
C9I78_RS22650	COG0534	Mate efflux family protein
C9I78_RS22660	COG5001	Diguanylate cyclase
C9I78_RS22670	COG3123	guanosine phosphorylase activity
C9I78_RS22710	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C9I78_RS22720	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C9I78_RS22725	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
C9I78_RS22740	COG2259	Doxx family
C9I78_RS22745	COG1741	Belongs to the pirin family
C9I78_RS22765	COG0363	glucosamine-6-phosphate deaminase activity
C9I78_RS22780	COG0786	glutamate:sodium symporter activity
C9I78_RS22785	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C9I78_RS22790	COG1131	(ABC) transporter
C9I78_RS22800	COG0786	glutamate:sodium symporter activity
C9I78_RS22835	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C9I78_RS22845	COG3279	Response regulator of the LytR AlgR family
C9I78_RS22850	COG3275	phosphorelay sensor kinase activity
C9I78_RS22870	COG1136	(ABC) transporter
C9I78_RS22885	COG0772	Belongs to the SEDS family
C9I78_RS22890	COG0217	transcriptional regulatory protein
C9I78_RS22915	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C9I78_RS22915	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
C9I78_RS22925	COG0444	Belongs to the ABC transporter superfamily
C9I78_RS22930	COG4608	Belongs to the ABC transporter superfamily
C9I78_RS22960	COG1444	tRNA N-acetyltransferase activity
C9I78_RS22980	COG3340	Belongs to the peptidase S51 family
C9I78_RS22985	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
C9I78_RS22990	COG1263	PTS System
C9I78_RS22990	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C9I78_RS22995	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
C9I78_RS23015	COG4166	transmembrane transport
C9I78_RS23065	COG0259	pyridoxamine-phosphate oxidase activity
C9I78_RS23095	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C9I78_RS23140	COG1132	(ABC) transporter
C9I78_RS23150	COG2207	Transcriptional regulator
C9I78_RS23175	COG0800	Aldolase
C9I78_RS23185	COG1904	glucuronate isomerase
C9I78_RS23190	COG0246	Mannitol dehydrogenase
C9I78_RS23200	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
C9I78_RS23210	COG2186	Transcriptional regulator
C9I78_RS23220	COG0513	Belongs to the DEAD box helicase family
C9I78_RS23225	COG2258	MOSC domain
C9I78_RS23240	COG1486	melibiose metabolic process
C9I78_RS23245	COG0583	DNA-binding transcription factor activity
C9I78_RS23265	COG1595	DNA-templated transcription, initiation
C9I78_RS23300	COG3634	alkyl hydroperoxide reductase activity
C9I78_RS23310	COG1846	Transcriptional regulator
C9I78_RS23315	COG1764	response to oxidative stress
C9I78_RS23340	COG2160	L-arabinose isomerase activity
C9I78_RS23350	COG1069	ribulokinase activity
C9I78_RS23355	COG1879	ABC-type sugar transport system periplasmic component
C9I78_RS23360	COG1129	ABC transporter
C9I78_RS23365	COG1172	Belongs to the binding-protein-dependent transport system permease family
C9I78_RS23370	COG0826	peptidase U32
C9I78_RS23400	COG1653	transport
C9I78_RS23405	COG0019	diaminopimelate decarboxylase activity
C9I78_RS23410	COG4264	IucA IucC family
C9I78_RS23435	COG4772	TonB-dependent receptor
C9I78_RS23440	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
C9I78_RS23445	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C9I78_RS23450	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C9I78_RS23455	COG1120	ATPase activity
C9I78_RS23460	COG0840	transmembrane signaling receptor activity
C9I78_RS23465	COG0612	Peptidase, M16
C9I78_RS23475	COG0739	heme binding
C9I78_RS23485	COG2814	Major facilitator Superfamily
C9I78_RS23500	COG4580	involved in the transport of maltose and maltodextrins
C9I78_RS23525	COG2356	endonuclease I
C9I78_RS23545	COG1982	Orn Lys Arg decarboxylase major
C9I78_RS23550	COG0531	amino acid
C9I78_RS23560	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
C9I78_RS23570	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
C9I78_RS23575	COG1162	GTPase activity
C9I78_RS23580	COG1263	PTS System
C9I78_RS23580	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C9I78_RS23590	COG1999	signal sequence binding
C9I78_RS23605	COG2909	trisaccharide binding
C9I78_RS23620	COG0058	SHG alpha-glucan phosphorylase activity
C9I78_RS23625	COG1640	4-alpha-glucanotransferase
C9I78_RS23630	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
C9I78_RS23635	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C9I78_RS23640	COG0366	Alpha amylase catalytic
C9I78_RS23655	COG3366	ferrous iron transmembrane transporter activity
C9I78_RS23660	COG0700	Nucleoside recognition
C9I78_RS23670	COG3339	Conserved Protein
C9I78_RS23675	COG1301	dicarboxylic acid transport
C9I78_RS23705	COG0583	DNA-binding transcription factor activity
C9I78_RS23720	COG3206	protein involved in exopolysaccharide biosynthesis
C9I78_RS23720	COG0489	protein tyrosine kinase activity
C9I78_RS23740	COG2095	MarC family integral membrane protein
C9I78_RS23745	COG4667	esterase of the alpha-beta hydrolase superfamily
C9I78_RS23750	COG3397	chitin binding
C9I78_RS23755	COG1054	Belongs to the UPF0176 family
C9I78_RS23770	COG1686	Belongs to the peptidase S11 family
C9I78_RS23795	COG0583	DNA-binding transcription factor activity
C9I78_RS23800	COG4628	conserved protein (DUF2132)
C9I78_RS23810	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C9I78_RS23820	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
C9I78_RS23825	COG0628	permease
C9I78_RS23870	COG2814	Major facilitator Superfamily
C9I78_RS23880	COG0454	-acetyltransferase
C9I78_RS23890	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C9I78_RS23895	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C9I78_RS23900	COG1882	Formate acetyltransferase
C9I78_RS23950	COG1360	Flagellar Motor Protein
C9I78_RS23955	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
C9I78_RS23960	COG1191	sigma factor activity
C9I78_RS23965	COG1580	Controls the rotational direction of flagella during chemotaxis
C9I78_RS23980	COG1516	flagellar protein fliS
C9I78_RS23985	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
C9I78_RS23995	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C9I78_RS24010	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
C9I78_RS24020	COG1987	bacterial-type flagellum assembly
C9I78_RS24100	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
C9I78_RS24120	COG0346	lactoylglutathione lyase activity
C9I78_RS24155	COG0745	RESPONSE REGULATOR receiver
C9I78_RS24175	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C9I78_RS24185	COG0156	8-amino-7-oxononanoate synthase activity
C9I78_RS24190	COG1063	alcohol dehydrogenase
C9I78_RS24230	COG0668	transmembrane transport
C9I78_RS24240	COG1304	FMN binding
C9I78_RS24245	COG1620	l-lactate permease
C9I78_RS24250	COG0583	DNA-binding transcription factor activity
C9I78_RS24255	COG1505	serine-type exopeptidase activity
C9I78_RS24260	COG4172	Belongs to the ABC transporter superfamily
C9I78_RS24270	COG1067	ATP-dependent peptidase activity
C9I78_RS24300	COG1247	-acetyltransferase
C9I78_RS24305	COG0437	4 iron, 4 sulfur cluster binding
C9I78_RS24310	COG0348	domain, Protein
C9I78_RS24325	COG1122	ATPase activity
C9I78_RS24330	COG4720	Psort location CytoplasmicMembrane, score
C9I78_RS24335	COG1566	PFAM secretion protein HlyD family protein
C9I78_RS24345	COG3706	GGDEF domain
C9I78_RS24360	COG0813	purine-nucleoside phosphorylase activity
C9I78_RS24370	COG3272	Protein of unknown function (DUF1722)
C9I78_RS24375	COG0789	Transcriptional regulator
C9I78_RS24380	COG0415	Belongs to the DNA photolyase family
C9I78_RS24385	COG1376	ErfK ybiS ycfS ynhG family protein
C9I78_RS24385	COG1388	LysM domain
C9I78_RS24395	COG0513	Belongs to the DEAD box helicase family
C9I78_RS24400	COG1770	oligopeptidase
C9I78_RS24405	COG4771	TonB-dependent receptor
C9I78_RS24435	COG0573	inorganic phosphate transmembrane transporter activity
C9I78_RS24440	COG0581	inorganic phosphate transmembrane transporter activity
C9I78_RS24445	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C9I78_RS24460	COG2304	oxidoreductase activity
C9I78_RS24480	COG0714	Associated with various cellular activities
C9I78_RS24490	COG0840	transmembrane signaling receptor activity
C9I78_RS24500	COG2197	response regulator
C9I78_RS24550	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
C9I78_RS24555	COG1120	ATPase activity
C9I78_RS24560	COG4774	siderophore transport
C9I78_RS24565	COG1132	(ABC) transporter
C9I78_RS24570	COG2205	protein histidine kinase activity
C9I78_RS24580	COG0569	domain protein
C9I78_RS24585	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C9I78_RS24590	COG3300	MHYT domain
C9I78_RS24590	COG5001	Diguanylate cyclase
C9I78_RS24595	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
C9I78_RS24600	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C9I78_RS24615	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C9I78_RS24615	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C9I78_RS24615	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C9I78_RS24620	COG2207	Transcriptional regulator
C9I78_RS24630	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C9I78_RS24635	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C9I78_RS24640	COG2084	Dehydrogenase
C9I78_RS24645	COG0753	catalase activity
C9I78_RS24655	COG2130	NADP-dependent
C9I78_RS24660	COG1309	transcriptional regulator
C9I78_RS24665	COG3097	Belongs to the UPF0267 family
C9I78_RS24720	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
C9I78_RS24725	COG3842	ATPase activity
C9I78_RS24735	COG1175	transmembrane transport
C9I78_RS24740	COG3833	ABC-type maltose transport systems, permease component
C9I78_RS24760	COG3746	phosphate-selective porin O and P
C9I78_RS24775	COG1028	Short-chain dehydrogenase reductase Sdr
C9I78_RS24800	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
C9I78_RS24810	COG0625	glutathione transferase activity
C9I78_RS24825	COG1686	Belongs to the peptidase S11 family
C9I78_RS24845	COG0678	peroxiredoxin activity
C9I78_RS24845	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C9I78_RS24850	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
C9I78_RS24870	COG1278	Cold shock
C9I78_RS24875	COG1741	Belongs to the pirin family
C9I78_RS24880	COG4667	esterase of the alpha-beta hydrolase superfamily
C9I78_RS24915	COG0673	inositol 2-dehydrogenase activity
C9I78_RS24920	COG2194	sulfuric ester hydrolase activity
C9I78_RS24925	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
C9I78_RS24935	COG2205	protein histidine kinase activity
C9I78_RS24940	COG0745	RESPONSE REGULATOR receiver
C9I78_RS24945	COG4221	oxidoreductase activity
C9I78_RS24965	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C9I78_RS24985	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C9I78_RS24995	COG2814	Major facilitator Superfamily
C9I78_RS25010	COG1418	mRNA catabolic process
C9I78_RS25020	COG0402	S-adenosylhomocysteine deaminase activity
C9I78_RS25025	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
C9I78_RS25035	COG2239	Acts as a magnesium transporter
C9I78_RS25040	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
C9I78_RS25045	COG1566	PFAM secretion protein HlyD family protein
C9I78_RS25070	COG0745	RESPONSE REGULATOR receiver
C9I78_RS25075	COG2205	protein histidine kinase activity
C9I78_RS25090	COG0531	amino acid
C9I78_RS25125	COG5002	protein histidine kinase activity
C9I78_RS25125	COG2205	protein histidine kinase activity
C9I78_RS25125	COG0784	Response regulator, receiver
C9I78_RS25130	COG0673	inositol 2-dehydrogenase activity
C9I78_RS25135	COG0534	Mate efflux family protein
C9I78_RS25145	COG2926	Belongs to the UPF0265 family
C9I78_RS25160	COG3132	Protein of unknown function, DUF480
C9I78_RS25165	COG2827	Endonuclease containing a URI domain
C9I78_RS25170	COG1879	ABC-type sugar transport system periplasmic component
C9I78_RS25175	COG2205	protein histidine kinase activity
C9I78_RS25175	COG0784	Response regulator, receiver
C9I78_RS25185	COG1566	PFAM secretion protein HlyD family protein
C9I78_RS25205	COG1522	sequence-specific DNA binding
C9I78_RS25235	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C9I78_RS25240	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C9I78_RS25260	COG0183	Belongs to the thiolase family
C9I78_RS25280	COG3005	denitrification pathway
C9I78_RS25290	COG0243	molybdopterin cofactor binding
C9I78_RS25300	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
C9I78_RS25305	COG3850	Histidine kinase
C9I78_RS25310	COG2197	response regulator
C9I78_RS25325	COG2195	Cleaves the N-terminal amino acid of tripeptides
C9I78_RS25345	COG0840	transmembrane signaling receptor activity
C9I78_RS25355	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C9I78_RS25370	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C9I78_RS25375	COG2814	Major facilitator Superfamily
C9I78_RS25385	COG0840	transmembrane signaling receptor activity
C9I78_RS25390	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
C9I78_RS25395	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C9I78_RS25425	COG2897	thiosulfate sulfurtransferase activity
C9I78_RS25445	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C9I78_RS25455	COG0302	gtp cyclohydrolase
C9I78_RS25460	COG1914	H( )-stimulated, divalent metal cation uptake system
C9I78_RS25470	COG0038	chloride channel
C9I78_RS25485	COG4989	oxidoreductase activity
C9I78_RS25500	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
C9I78_RS25500	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
C9I78_RS25505	COG0516	GMP reductase activity
C9I78_RS25510	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C9I78_RS25580	COG0674	pyruvate-flavodoxin oxidoreductase activity
C9I78_RS25580	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
C9I78_RS25585	COG1013	pyruvate-flavodoxin oxidoreductase activity
C9I78_RS25590	COG3474	cytochrome
C9I78_RS25600	COG0789	Transcriptional regulator
C9I78_RS25605	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C9I78_RS25610	COG0384	phenazine biosynthesis protein PhzF
C9I78_RS25620	COG1294	oxidase, subunit
C9I78_RS25625	COG1271	oxidase subunit
C9I78_RS25630	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C9I78_RS25635	COG0110	maltose O-acetyltransferase activity
C9I78_RS25645	COG3264	Mechanosensitive ion channel
C9I78_RS25645	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
C9I78_RS25660	COG3850	Histidine kinase
C9I78_RS25660	COG4999	Histidine kinase
C9I78_RS25660	COG2205	protein histidine kinase activity
C9I78_RS25660	COG3437	response regulator, receiver
C9I78_RS25680	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C9I78_RS25685	COG1960	acyl-CoA dehydrogenase activity
C9I78_RS25695	COG0183	Belongs to the thiolase family
C9I78_RS25705	COG1960	acyl-CoA dehydrogenase activity
C9I78_RS25710	COG1024	Enoyl-CoA hydratase
C9I78_RS25725	COG1028	Short-chain dehydrogenase reductase Sdr
C9I78_RS25735	COG3706	GGDEF domain
C9I78_RS25740	COG1309	transcriptional regulator
C9I78_RS25745	COG1012	belongs to the aldehyde dehydrogenase family
C9I78_RS25760	COG4176	ABC-type proline glycine betaine transport system permease component
C9I78_RS25765	COG4175	Glycine betaine
C9I78_RS25765	COG0517	IMP dehydrogenase activity
C9I78_RS25780	COG0330	HflC and HflK could
C9I78_RS25790	COG5001	Diguanylate cyclase
C9I78_RS25790	COG3300	MHYT domain
C9I78_RS25810	COG2205	protein histidine kinase activity
C9I78_RS25810	COG0784	Response regulator, receiver
C9I78_RS25830	COG4974	Belongs to the 'phage' integrase family
C9I78_RS25850	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C9I78_RS25905	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
C9I78_RS25945	COG0582	viral genome integration into host DNA
C9I78_RS25985	COG2189	Belongs to the N(4) N(6)-methyltransferase family
C9I78_RS26005	COG3706	GGDEF domain
C9I78_RS26035	COG2003	Belongs to the UPF0758 family
C9I78_RS26060	COG2003	Belongs to the UPF0758 family
C9I78_RS26080	COG4962	Type ii secretion system protein e
C9I78_RS26155	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C9I78_RS26175	COG0681	Belongs to the peptidase S26 family
C9I78_RS26190	COG2948	multi-organism process
C9I78_RS26205	COG3701	Conjugal transfer protein
C9I78_RS26225	COG3451	type IV secretory pathway VirB4
C9I78_RS26255	COG1192	Involved in chromosome partitioning
C9I78_RS26290	COG0419	ATPase involved in DNA repair
C9I78_RS26315	COG1192	Involved in chromosome partitioning
C9I78_RS26360	COG5268	conjugation
C9I78_RS26365	COG3451	type IV secretory pathway VirB4
C9I78_RS26375	COG4962	Type ii secretion system protein e
C9I78_RS26390	COG3504	Conjugal transfer protein
C9I78_RS26425	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB