locus-tag	class	description
VP_RS00005	ENOG4105QTB	Flavodoxin
VP_RS00010	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
VP_RS00015	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
VP_RS00025	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
VP_RS00040	ENOG4105E5Q	amino acid AbC transporter
VP_RS00045	ENOG4105EAB	amino acid AbC transporter
VP_RS00050	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
VP_RS00055	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
VP_RS00060	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
VP_RS00065	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
VP_RS00075	ENOG4108ZNX	Heat shock protein
VP_RS00080	ENOG4105JKW	Valine--pyruvate aminotransferase
VP_RS00085	ENOG4107T9C	Alpha amylase catalytic region
VP_RS00090	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
VP_RS00095	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
VP_RS00110	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
VP_RS00125	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
VP_RS00130	ENOG4105CHU	acetyl-coa acetyltransferase
VP_RS00135	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
VP_RS00140	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
VP_RS00145	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
VP_RS00150	ENOG4108RR8	protoporphyrinogen oxidase
VP_RS00185	ENOG4105EMY	transcriptional regulator
VP_RS00190	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
VP_RS00195	ENOG4105W0Z	cytoplasmic protein
VP_RS00200	ENOG4105BZS	acriflavin resistance protein
VP_RS00205	ENOG410624X	efflux transporter, rnd family, mfp subunit
VP_RS00210	ENOG41067SE	Tetr family transcriptional regulator
VP_RS00215	ENOG4105C4R	Atp-dependent dna helicase
VP_RS00220	ENOG4105MPD	Cytochrome
VP_RS00255	ENOG4108JQ6	ABC transporter
VP_RS00260	ENOG4105DEF	Extracellular solute-binding protein, family 5
VP_RS00265	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
VP_RS00270	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
VP_RS00300	ENOG4105D9P	serine threonine protein kinase
VP_RS00305	ENOG4105DIQ	Transcriptional regulator
VP_RS00310	ENOG41064T2	transcriptional regulator, lysR family
VP_RS00315	ENOG41090TI	Catalyzes the excretion of spermidine (By similarity)
VP_RS00325	ENOG4105C01	Dihydroxy-acid dehydratase
VP_RS00330	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
VP_RS00335	ENOG4105C6Z	Gluconate
VP_RS00340	ENOG4108UHU	Aldolase
VP_RS00345	ENOG4107U5R	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
VP_RS00350	ENOG4107RSM	transcriptional regulator
VP_RS00355	ENOG4105DC8	reductase
VP_RS00360	ENOG4105D6S	protein involved in catabolism of external DNA
VP_RS00365	ENOG4105DGW	oligopeptidase A
VP_RS00370	ENOG4108VVK	transcriptional Regulator, AsnC
VP_RS00375	ENOG4105BZU	Histidine kinase
VP_RS00380	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
VP_RS00390	ENOG4105EMK	carboxylate amino acid amine transporter
VP_RS00395	ENOG4108M6U	Universal stress protein A
VP_RS00400	ENOG41090A1	ferritin
VP_RS00405	ENOG4108V6B	universal stress protein B
VP_RS00410	ENOG4105CBX	hi0933 family
VP_RS00415	ENOG4108JUA	Transcriptional regulator
VP_RS00440	ENOG4107TE5	Lipid kinase
VP_RS00470	ENOG4105DSF	transport protein
VP_RS00475	ENOG4105BZU	Histidine kinase
VP_RS00485	ENOG4105CGY	Dna recombination protein
VP_RS00490	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
VP_RS00495	ENOG4105JC1	sterol-binding domain protein
VP_RS00500	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
VP_RS00505	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
VP_RS00510	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
VP_RS00515	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
VP_RS00520	ENOG4105F8V	Hydrolase, tatD family
VP_RS00525	ENOG4105D52	delta-aminolevulinic acid dehydratase
VP_RS00535	ENOG4105C2M	dna polymerase I
VP_RS00540	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
VP_RS00545	ENOG4106RE7	Cytochrome
VP_RS00560	ENOG4105XCT	Protein of unknown function (DUF2489)
VP_RS00565	ENOG4105D4P	Coproporphyrinogen iii oxidase
VP_RS00570	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
VP_RS00575	ENOG4105BZU	Histidine kinase
VP_RS00580	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
VP_RS00585	ENOG4105CUX	Signal transduction histidine kinase
VP_RS00595	ENOG4105C5F	glutamine synthetase
VP_RS00600	ENOG4105CI3	gtp-binding protein typa
VP_RS00615	ENOG4107S2Z	UPF0761 membrane protein
VP_RS00620	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
VP_RS00625	ENOG4105SUU	thioesterase domain
VP_RS00635	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
VP_RS00640	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
VP_RS00645	ENOG4105VEJ	Heat shock protein
VP_RS00650	ENOG4108XKW	General secretion pathway protein C
VP_RS00660	ENOG4107QHF	type ii secretion system protein e
VP_RS00665	ENOG4105D7Q	type ii secretion system
VP_RS00670	ENOG4108VAU	general secretion pathway protein G
VP_RS00675	ENOG4105VWV	general secretion pathway protein h
VP_RS00680	ENOG4105X5Z	General secretion pathway protein I
VP_RS00685	ENOG4108WWZ	General secretion pathway protein J
VP_RS00690	ENOG4108RTD	type II secretion system protein K
VP_RS00695	ENOG4108BY5	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins (By similarity)
VP_RS00700	ENOG4105U1E	general secretion pathway protein M
VP_RS00705	ENOG4105PIC	general secretion pathway protein N
VP_RS00715	ENOG4107RK2	ADP-ribose diphosphatase NudE
VP_RS00720	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
VP_RS00725	ENOG4105MJ2	Competence protein
VP_RS00730	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
VP_RS00740	ENOG4105BZM	domain protein
VP_RS00750	ENOG4108RRZ	Transcription elongation factor GreB
VP_RS00765	ENOG4105E0F	Histidine kinase
VP_RS00770	ENOG4105C2W	permease
VP_RS00775	ENOG4105CB5	ATP-dependent DNA helicase recG
VP_RS00780	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
VP_RS00785	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
VP_RS00790	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
VP_RS00795	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
VP_RS00810	ENOG4109015	Biopolymer transport protein exbD tolR
VP_RS00830	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
VP_RS00835	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
VP_RS00840	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
VP_RS00845	ENOG4107QRA	Extracellular solute-binding protein, family 5
VP_RS00865	ENOG4105DSJ	YicC domain protein
VP_RS00870	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
VP_RS00875	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
VP_RS00880	ENOG4105D1S	lipid A biosynthesis
VP_RS00885	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
VP_RS00890	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
VP_RS00895	ENOG4105C8Q	Methyl-accepting chemotaxis
VP_RS00900	ENOG4105W5Q	DNA repair protein (RadC
VP_RS00905	ENOG4105KDC	50s ribosomal protein l28
VP_RS00915	ENOG4108I6E	Sulfatase
VP_RS00925	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
VP_RS00930	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
VP_RS00935	ENOG4108JMC	lipopolysaccharide core biosynthesis protein
VP_RS00945	ENOG4106WTF	Glycosyl transferase, family 2
VP_RS00950	ENOG4105DKP	glycosyl transferase, family 9
VP_RS00955	ENOG41080IJ	Diacylglycerol kinase
VP_RS00960	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
VP_RS00970	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
VP_RS00975	ENOG4107SE4	UDP-N-acetylglucosamine 2-epimerase
VP_RS00980	ENOG4105D2T	synthase
VP_RS00990	ENOG4105CNB	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
VP_RS01035	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
VP_RS01040	ENOG4105XA0	heptosyltransferase ii
VP_RS01045	ENOG4105NWR	lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase
VP_RS01050	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
VP_RS01055	ENOG4105E3R	(LipO)protein
VP_RS01090	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
VP_RS01095	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
VP_RS01125	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
VP_RS01135	ENOG4105D3Q	Sugar transferase
VP_RS01150	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
VP_RS01165	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
VP_RS01170	ENOG4105CY0	Metallo-Beta-Lactamase
VP_RS01175	ENOG4105CP7	Triose-phosphate isomerase
VP_RS01200	ENOG4105CBT	Fructose-1,6-bisphosphatase
VP_RS01205	ENOG41065UX	Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA (By similarity)
VP_RS01210	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
VP_RS01215	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
VP_RS01220	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
VP_RS01225	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
VP_RS01235	ENOG4105ETE	Transcriptional regulator (LacI family
VP_RS01240	ENOG4105C25	Primosomal protein n'
VP_RS01245	ENOG4105VFB	Binds the 23S rRNA (By similarity)
VP_RS01250	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
VP_RS01255	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
VP_RS01260	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
VP_RS01265	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
VP_RS01270	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
VP_RS01275	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
VP_RS01280	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
VP_RS01285	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
VP_RS01290	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
VP_RS01295	ENOG41083MP	50s ribosomal protein l29
VP_RS01300	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
VP_RS01305	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
VP_RS01310	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
VP_RS01315	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
VP_RS01320	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
VP_RS01325	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
VP_RS01330	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
VP_RS01340	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
VP_RS01345	ENOG4105VPB	50S ribosomal protein L30
VP_RS01350	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
VP_RS01355	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
VP_RS01365	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
VP_RS01370	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
VP_RS01375	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
VP_RS01380	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
VP_RS01385	ENOG4108ZT0	50S ribosomal protein l17
VP_RS01395	ENOG4108V1T	peptidylprolyl cis-trans isomerase
VP_RS01405	ENOG4107YB6	acetyltransferase, (GNAT) family
VP_RS01410	ENOG4105C1J	atp-dependent rna helicase
VP_RS01420	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
VP_RS01425	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
VP_RS01430	ENOG4105C11	sulfate adenylyltransferase), subunit 2
VP_RS01435	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
VP_RS01445	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
VP_RS01465	ENOG4108I0Y	(ABC) transporter
VP_RS01480	ENOG4108UUE	Transcriptional regulator
VP_RS01485	ENOG41061GZ	Protein of unknown function (DUF1107)
VP_RS01490	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
VP_RS01495	ENOG4105CFU	surface antigen
VP_RS01505	ENOG41066HZ	AIG2-like family
VP_RS01515	ENOG4105F0N	pyrophosphate phospho-hydrolase
VP_RS01520	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
VP_RS01525	ENOG4105DFU	Cell wall formation (By similarity)
VP_RS01530	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
VP_RS01535	ENOG4105DP9	ABC transporter
VP_RS01540	ENOG4106SMU	thiamine transporter membrane protein
VP_RS01545	ENOG4107T0D	ABC, transporter
VP_RS01560	ENOG4105H1G	trap transporter solute receptor taxi family
VP_RS01565	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
VP_RS01570	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
VP_RS01580	ENOG4105EAH	synthase
VP_RS01585	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
VP_RS01590	ENOG4105K46	50S ribosomal protein l27
VP_RS01595	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
VP_RS01600	ENOG4105DWK	Membrane
VP_RS01610	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
VP_RS01615	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
VP_RS01620	ENOG4105NWN	ApaG protein
VP_RS01625	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
VP_RS01630	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
VP_RS01635	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
VP_RS01640	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
VP_RS01645	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
VP_RS01655	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
VP_RS01660	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
VP_RS01665	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
VP_RS01670	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
VP_RS01690	ENOG41064T2	transcriptional regulator, lysR family
VP_RS01695	ENOG4108IQE	Amp-dependent synthetase and ligase
VP_RS01700	ENOG4105C7K	acetolactate synthase
VP_RS01705	ENOG4108ZP8	Acetolactate synthase small subunit
VP_RS01710	ENOG4105BZU	Histidine kinase
VP_RS01720	ENOG4105CA9	Pyruvate kinase
VP_RS01725	ENOG410804X	Transcriptional regulator
VP_RS01730	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
VP_RS01745	ENOG4105GR3	Histidine kinase
VP_RS01755	ENOG4105CMT	Dihydroxyacetone kinase
VP_RS01760	ENOG4108UTZ	Dihydroxyacetone kinase
VP_RS01775	ENOG4105E61	Mannitol repressor protein
VP_RS01780	ENOG4107SQ3	mannitol-1-phosphate 5-dehydrogenase
VP_RS01785	ENOG4105CTS	PTS system mannitol-specific
VP_RS01825	ENOG4105D01	(LipO)protein
VP_RS01860	ENOG4107QTH	restriction modification system DNA specificity domain
VP_RS01915	ENOG4105CAF	HipA N-terminal domain protein
VP_RS01930	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
VP_RS01935	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
VP_RS01940	ENOG4105KTH	gatB Yqey
VP_RS01945	ENOG4105VCC	30S ribosomal protein S21
VP_RS01950	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
VP_RS01955	ENOG4108WC5	Alpha Beta Hydrolase Fold protein
VP_RS01960	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
VP_RS01965	ENOG4107ZVW	dihydroneopterin aldolase
VP_RS01970	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
VP_RS01975	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
VP_RS01980	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
VP_RS01995	ENOG4106MWK	domain protein
VP_RS02000	ENOG4105CJ3	phosphate transporter
VP_RS02005	ENOG4107IX6	phosphate transport regulator
VP_RS02010	ENOG4105I7R	Adenylate cyclase
VP_RS02020	ENOG4108NVR	Methyl-accepting chemotaxis
VP_RS02025	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
VP_RS02030	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
VP_RS02035	ENOG4105DFG	type I secretion outer membrane protein
VP_RS02040	ENOG41087AY	ADP-Ribose pyrophosphatase
VP_RS02045	ENOG4108SX3	cytoplasmic protein
VP_RS02050	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
VP_RS02055	ENOG4105IPS	esterase
VP_RS02060	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
VP_RS02065	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
VP_RS02070	ENOG4105C0H	protease
VP_RS02075	ENOG4105C0H	protease
VP_RS02080	ENOG4108W2Q	Cytochrome d ubiquinol oxidase subunit III
VP_RS02085	ENOG4105D6Z	AFG1 family ATPase
VP_RS02090	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
VP_RS02095	ENOG4108UJD	30S ribosomal protein S9
VP_RS02100	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
VP_RS02105	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
VP_RS02110	ENOG4105EIX	cytochrome c1
VP_RS02115	ENOG4107MKT	Stringent starvation protein a
VP_RS02120	ENOG4105KB2	stringent starvation protein b
VP_RS02125	ENOG4105W4M	Transport-associated protein
VP_RS02130	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
VP_RS02135	ENOG41082RQ	UPF0102 protein
VP_RS02145	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
VP_RS02155	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
VP_RS02160	ENOG41063Y6	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
VP_RS02165	ENOG4105CJN	penicillin-binding protein
VP_RS02170	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
VP_RS02175	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
VP_RS02180	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
VP_RS02185	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
VP_RS02195	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
VP_RS02200	ENOG4105DFU	Cell wall formation (By similarity)
VP_RS02205	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
VP_RS02210	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
VP_RS02215	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
VP_RS02220	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
VP_RS02230	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
VP_RS02235	ENOG4105M6F	mutator MutT protein
VP_RS02240	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
VP_RS02245	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
VP_RS02250	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
VP_RS02265	ENOG4105EJ9	Membrane
VP_RS02270	ENOG4105VP0	transcriptional regulator, lysR family
VP_RS02275	ENOG4105EN6	Membrane
VP_RS02280	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
VP_RS02285	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
VP_RS02290	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
VP_RS02300	ENOG4105BZ8	glutamate synthase
VP_RS02305	ENOG4105CBC	glutamate synthase
VP_RS02320	ENOG4105N5T	Radical SAM Protein
VP_RS02330	ENOG4105BZU	Histidine kinase
VP_RS02340	ENOG41065U4	response regulator
VP_RS02350	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
VP_RS02365	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
VP_RS02370	ENOG4105D98	threonine synthase
VP_RS02375	ENOG4108VKA	Acts as a radical domain for damaged PFL and possibly other radical proteins (By similarity)
VP_RS02380	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
VP_RS02385	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
VP_RS02400	ENOG4105BZG	amino acid carrier protein
VP_RS02405	ENOG4105D1Q	UPF0246 protein
VP_RS02410	ENOG4105C1J	atp-dependent rna helicase
VP_RS02415	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
VP_RS02420	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
VP_RS02425	ENOG41071R3	Low-potential electron donor to a number of redox enzymes (By similarity)
VP_RS02435	ENOG4105T95	Thiol disulfide interChange protein
VP_RS02440	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
VP_RS02450	ENOG4105CRK	lysyL-tRNA synthetase
VP_RS02455	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
VP_RS02465	ENOG4105CPC	Aldo Keto reductase
VP_RS02475	ENOG4105IRT	Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair (By similarity)
VP_RS02480	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
VP_RS02485	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
VP_RS02490	ENOG4105HF0	Membrane
VP_RS02495	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
VP_RS02500	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
VP_RS02515	ENOG41063Z6	transcriptional regulator, lysR family
VP_RS02520	ENOG41080HT	Transcriptional regulator, arsr family
VP_RS02525	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
VP_RS02530	ENOG4105CJR	Integral membrane protein (MviN
VP_RS02535	ENOG4105DTN	riboflavin biosynthesis protein ribF
VP_RS02540	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
VP_RS02545	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
VP_RS02550	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
VP_RS02555	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
VP_RS02560	ENOG4108NEV	two component transcriptional regulator, LytTR family
VP_RS02565	ENOG4108HRK	Histidine kinase
VP_RS02585	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
VP_RS02590	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
VP_RS02595	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
VP_RS02600	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
VP_RS02605	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
VP_RS02610	ENOG4105DR5	peptidase
VP_RS02620	ENOG4105C5H	ABC transporter
VP_RS02625	ENOG4107SC1	transglycosylase
VP_RS02630	ENOG4105R9M	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity)
VP_RS02635	ENOG4108K16	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
VP_RS02645	ENOG4108WPH	sigma 54 modulation protein ribosomal protein S30EA
VP_RS02650	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
VP_RS02655	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VP_RS02660	ENOG4105C34	Pseudouridine synthase
VP_RS02665	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
VP_RS02670	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
VP_RS02725	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
VP_RS02730	ENOG4105CFP	Peptidase U32
VP_RS02735	ENOG4105DH7	May be involved in recombination (By similarity)
VP_RS02740	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
VP_RS02745	ENOG4105BZU	Histidine kinase
VP_RS02750	ENOG4105DJH	phosphate
VP_RS02755	ENOG4105C9X	ppx gppa phosphatase
VP_RS02760	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
VP_RS02765	ENOG4105C8U	phosphate abc transporter
VP_RS02770	ENOG4105E2Z	phosphate ABC transporter (Permease
VP_RS02775	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
VP_RS02785	ENOG4105CSR	polyphosphate kinase 2
VP_RS02790	ENOG4106N3A	copper homeostasis protein cutc
VP_RS02795	ENOG4105D3R	alkyl hydroperoxide reductase
VP_RS02800	ENOG4105C5Q	Transcriptional regulator
VP_RS02805	ENOG4107QP3	malate synthase g
VP_RS02810	ENOG4108I9X	Isocitrate lyase
VP_RS02815	ENOG4105W87	Cbs domain
VP_RS02825	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
VP_RS02830	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
VP_RS02835	ENOG4105VIE	preprotein translocase, subunit YajC
VP_RS02840	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
VP_RS02845	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
VP_RS02850	ENOG4105ECY	inositol monophosphatase
VP_RS02855	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
VP_RS02860	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
VP_RS02865	ENOG4105C3J	Cysteine desulfurase
VP_RS02870	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
VP_RS02875	ENOG4108Z4V	iron-sulfur cluster assembly
VP_RS02880	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
VP_RS02885	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
VP_RS02890	ENOG4108ZIT	Ferredoxin, 2FE-2S
VP_RS02895	ENOG4105WVQ	Fe-S assembly protein IscX
VP_RS02900	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
VP_RS02905	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
VP_RS02910	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
VP_RS02920	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
VP_RS02925	ENOG4105CUT	histidyl-tRNA synthetase
VP_RS02930	ENOG4105N21	Membrane
VP_RS02935	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
VP_RS02940	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
VP_RS02955	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
VP_RS02960	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
VP_RS02965	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
VP_RS02970	ENOG4107S6Z	Na H antiporter
VP_RS02980	ENOG4106HK8	GPR1 FUN34 yaaH family protein
VP_RS02990	ENOG4105BZG	amino acid carrier protein
VP_RS02995	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
VP_RS03020	ENOG4108IQK	o-acetylhomoserine
VP_RS03025	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
VP_RS03045	ENOG4105DGM	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
VP_RS03050	ENOG4105ETT	transcriptional Regulator, LysR family
VP_RS03080	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
VP_RS03095	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
VP_RS03100	ENOG4108Z1B	Cyclase dehydrase
VP_RS03105	ENOG4105VDB	UPF0125 protein
VP_RS03110	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
VP_RS03115	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
VP_RS03125	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
VP_RS03130	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
VP_RS03140	ENOG4105CFG	Acts as a chaperone (By similarity)
VP_RS03145	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
VP_RS03175	ENOG4105CFC	Transporter
VP_RS03180	ENOG4108Z6B	deaminase
VP_RS03185	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
VP_RS03190	ENOG4108ETH	Formylglycinamide ribotide synthetase
VP_RS03215	ENOG4105CIN	aminoacyl-histidine dipeptidase
VP_RS03220	ENOG4105C7N	Xanthine uracil vitamin C permease
VP_RS03225	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
VP_RS03230	ENOG4108DJV	Fermentation respiration switch protein
VP_RS03235	ENOG4108UVK	Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32 (By similarity)
VP_RS03240	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
VP_RS03245	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
VP_RS03250	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
VP_RS03255	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
VP_RS03270	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
VP_RS03275	ENOG4107YIM	Involved in the transcription termination process (By similarity)
VP_RS03280	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
VP_RS03285	ENOG4108ZAI	phosphatidylglycerophosphatase a
VP_RS03290	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
VP_RS03295	ENOG4105CTB	Polyprenyl synthetase
VP_RS03300	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
VP_RS03305	ENOG4105E14	MotA TolQ exbB proton channel
VP_RS03310	ENOG4107QKZ	Ompa motb domain protein
VP_RS03315	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
VP_RS03320	ENOG4105ETT	transcriptional Regulator, LysR family
VP_RS03330	ENOG4105M08	Membrane
VP_RS03335	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
VP_RS03345	ENOG4105CIQ	May have a role in processing of nucleic acids. It is probably not an exonuclease
VP_RS03350	ENOG4105EWT	decarboxylase family
VP_RS03365	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
VP_RS03370	ENOG4108T6E	Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function (By similarity)
VP_RS03375	ENOG4105EXF	Zn-ribbon-containing, possibly nucleic-acid-binding protein
VP_RS03380	ENOG4105D01	(LipO)protein
VP_RS03385	ENOG4108UMI	ABC transporter, permease
VP_RS03390	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
VP_RS03395	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
VP_RS03400	ENOG4105D4X	repressor
VP_RS03405	ENOG4105C5Y	PTS System
VP_RS03410	ENOG4105CG3	alpha amylase, catalytic region
VP_RS03425	ENOG4108JYZ	YitT family
VP_RS03430	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
VP_RS03435	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
VP_RS03440	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
VP_RS03445	ENOG4108Z43	UPF0250 protein
VP_RS03450	ENOG4105DZ1	carboxypeptidase
VP_RS03455	ENOG4105K6T	rare lipoprotein A
VP_RS03460	ENOG4105CNI	cell division protein FtsW
VP_RS03465	ENOG4105CJN	penicillin-binding protein
VP_RS03470	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
VP_RS03475	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
VP_RS03480	ENOG4105DJF	DNA polymerase III, delta' subunit
VP_RS03485	ENOG4108U2H	Rare lipoprotein B
VP_RS03490	ENOG4105C8T	Leucyl-tRNA synthetase
VP_RS03495	ENOG4107PAI	alpha helical protein
VP_RS03500	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
VP_RS03505	ENOG4108JU5	Magnesium and cobalt efflux protein
VP_RS03510	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
VP_RS03515	ENOG4105C9A	Phoh family
VP_RS03520	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
VP_RS03525	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
VP_RS03640	ENOG4105C3G	gtp-binding protein
VP_RS03645	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
VP_RS03650	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
VP_RS03655	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
VP_RS03660	ENOG4105C1U	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
VP_RS03665	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
VP_RS03670	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
VP_RS03675	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
VP_RS03680	ENOG4108YY7	Invasion gene expression up-regulator SirB
VP_RS03685	ENOG41063JG	Transcriptional regulator
VP_RS03690	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
VP_RS03695	ENOG4105CGH	5'-nucleotidase
VP_RS03700	ENOG4108Z66	YbaK ebsC protein
VP_RS03705	ENOG4105FE9	pseudouridine synthase
VP_RS03710	ENOG4108DG9	Smr protein MutS2
VP_RS03730	ENOG4105E2D	ec 3.2.1.52
VP_RS03745	ENOG4105C59	p-type ATPase
VP_RS03750	ENOG41081QG	Porin Gram-negative type
VP_RS03760	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
VP_RS03765	ENOG4105UYK	outer membrane protein a
VP_RS03810	ENOG4107R88	Chemotaxis protein (CheV)
VP_RS03815	ENOG4105BZU	Histidine kinase
VP_RS03820	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
VP_RS03825	ENOG4108ZC9	flagellar basal-body rod protein flgc
VP_RS03830	ENOG4105W00	Flagellar hook capping protein
VP_RS03835	ENOG4105BZE	flagellar hook protein, FlgE
VP_RS03840	ENOG4108KPB	Flagellar basal-body rod protein FlgF
VP_RS03845	ENOG4105CGA	flagellar basal-body rod protein FlgG
VP_RS03850	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
VP_RS03855	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
VP_RS03860	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
VP_RS03870	ENOG4105DTJ	flagellar hook-associated protein
VP_RS03875	ENOG4105I03	Flagellin
VP_RS03880	ENOG4105I03	Flagellin
VP_RS03890	ENOG4105C5Y	PTS System
VP_RS03895	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
VP_RS03900	ENOG4105KZ7	phosphocarrier protein hpr
VP_RS03905	ENOG4105C6T	cysteine synthase
VP_RS03910	ENOG4105EXN	Sulfate transport protein CysZ
VP_RS03915	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
VP_RS03920	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
VP_RS03940	ENOG4107QX8	SPFH domain, Band 7 family protein
VP_RS03945	ENOG4107QR8	Thioredoxin
VP_RS03950	ENOG4105E1F	short-chain dehydrogenase reductase
VP_RS03955	ENOG4105ECP	epimerase
VP_RS03980	ENOG4108RE9	Phosphodiesterase
VP_RS04000	ENOG4108DQ1	activator toxR
VP_RS04005	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
VP_RS04010	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
VP_RS04015	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
VP_RS04020	ENOG4105DUX	Transporter
VP_RS04025	ENOG4105MDZ	Transcriptional activator rfaH
VP_RS04030	ENOG4105CAQ	asparagine synthetase
VP_RS04035	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
VP_RS04040	ENOG4105E2R	ROK family
VP_RS04045	ENOG4105CE4	GlcNAc 6-P deacetylase
VP_RS04055	ENOG4105CX6	glutaminyL-tRNA synthetase
VP_RS04060	ENOG41090R7	Ferric uptake
VP_RS04070	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
VP_RS04080	ENOG4105EV9	Alpha Beta Hydrolase
VP_RS04085	ENOG4107CDU	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity)
VP_RS04090	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
VP_RS04100	ENOG4107QNR	UPF0135 protein
VP_RS04105	ENOG4105BZN	citrate synthase
VP_RS04110	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
VP_RS04115	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
VP_RS04120	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
VP_RS04125	ENOG4105E33	succinate dehydrogenase
VP_RS04130	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
VP_RS04135	ENOG4105C7S	Dehydrogenase
VP_RS04140	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
VP_RS04145	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
VP_RS04150	ENOG4105FAV	ABC, transporter
VP_RS04155	ENOG4105FDK	ABC transporter
VP_RS04160	ENOG4105NXV	High-affinity zinc uptake system protein
VP_RS04165	ENOG4107S4Z	Activates expression of the rhaBAD and rhaT operons (By similarity)
VP_RS04170	ENOG4105XFK	Ferrous iron transport protein A
VP_RS04175	ENOG4105CE1	Ferrous iron transport protein b
VP_RS04190	ENOG4105C75	arginyL-tRNA synthetase
VP_RS04195	ENOG4106ZCM	YecM protein
VP_RS04200	ENOG4105CIY	formyltetrahydrofolate deformylase
VP_RS04205	ENOG4105DVT	helicase
VP_RS04210	ENOG41072GX	Peptidase M22 Glycoprotease
VP_RS04225	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
VP_RS04230	ENOG4105CEY	Amp-dependent synthetase and ligase
VP_RS04235	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
VP_RS04240	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
VP_RS04245	ENOG4107QMS	site-determining protein
VP_RS04250	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
VP_RS04255	ENOG4105VNG	YcgL domain-containing protein
VP_RS04260	ENOG4105CVE	Lytic murein transglycosylase
VP_RS04265	ENOG4105CC0	LysR family Transcriptional regulator
VP_RS04270	ENOG4105D9N	nucleoside
VP_RS04275	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
VP_RS04290	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
VP_RS04295	ENOG4105C2D	reductase
VP_RS04305	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
VP_RS04330	ENOG4105C84	Histidine ammonia-lyase
VP_RS04335	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
VP_RS04340	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
VP_RS04360	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
VP_RS04400	ENOG4105C1J	atp-dependent rna helicase
VP_RS04405	ENOG4107ZYR	domain protein
VP_RS04425	ENOG4105CNG	UPF0061 protein
VP_RS04430	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
VP_RS04435	ENOG410835K	Tripartite ATP-Independent Periplasmic transporter DctQ
VP_RS04440	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
VP_RS04455	ENOG4105CQZ	Histidine kinase
VP_RS04465	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
VP_RS04470	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
VP_RS04475	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
VP_RS04480	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
VP_RS04485	ENOG4105K70	DNA-binding protein
VP_RS04490	ENOG4105EIN	peptidylprolyl cis-trans isomerase
VP_RS04495	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
VP_RS04510	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
VP_RS04515	ENOG4105DK2	UPF0207 protein
VP_RS04520	ENOG4105CHM	Aminotransferase
VP_RS04525	ENOG4105E4F	Isochorismate synthase
VP_RS04530	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
VP_RS04535	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
VP_RS04540	ENOG4108IPT	Naphthoate synthase
VP_RS04550	ENOG4105CEY	Amp-dependent synthetase and ligase
VP_RS04560	ENOG4105HMI	Membrane
VP_RS04565	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
VP_RS04615	ENOG4105BZS	acriflavin resistance protein
VP_RS04640	ENOG4108XM1	transcriptional regulator AsnC family
VP_RS04650	ENOG4105C29	acyl-CoA thioesterase
VP_RS04655	ENOG4108MNP	Glycoprotein polysaccharide metabolism
VP_RS04670	ENOG4108KHX	Diguanylate cyclase
VP_RS04685	ENOG4108Z4U	Ferredoxin
VP_RS04690	ENOG4105DZ0	fad dependent oxidoreductase
VP_RS04695	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
VP_RS04705	ENOG4107SXA	Phosphorylase
VP_RS04715	ENOG4108NVR	Methyl-accepting chemotaxis
VP_RS04720	ENOG4105K59	histidine triad (HIT) protein
VP_RS04745	ENOG4105D0Y	UPF0227 protein
VP_RS04750	ENOG4105CEP	NADH dehydrogenase
VP_RS04765	ENOG4108JA2	transcriptioN-repair coupling factor
VP_RS04775	ENOG4105D60	lipoprotein releasing system transmembrane protein
VP_RS04780	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
VP_RS04785	ENOG4105D60	lipoprotein releasing system transmembrane protein
VP_RS04795	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
VP_RS04800	ENOG4105BZ1	(ABC) transporter
VP_RS04805	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
VP_RS04810	ENOG4105W49	UPF0434 protein
VP_RS04815	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
VP_RS04820	ENOG4105ED1	spovr family
VP_RS04825	ENOG4106AKX	UPF0229 protein
VP_RS04830	ENOG4105CYN	Serine protein kinase
VP_RS04835	ENOG4105XWI	UPF0304 protein
VP_RS04845	ENOG4105F1A	Pyruvate formate-lyase
VP_RS04855	ENOG4105C6N	Formate acetyltransferase
VP_RS04870	ENOG4108JEH	abc transporter atp-binding protein
VP_RS04875	ENOG4105E89	ABC transporter
VP_RS04880	ENOG4105DSP	amino acid AbC transporter
VP_RS04895	ENOG4105CGK	Exodeoxyribonuclease III
VP_RS04900	ENOG4106428	Protein of unknown function (DUF2496)
VP_RS04905	ENOG4108URS	primosomal replication protein n''
VP_RS04910	ENOG4105EJ9	Membrane
VP_RS04915	ENOG4105DVT	helicase
VP_RS04930	ENOG4108R99	pseudouridine synthase
VP_RS04940	ENOG4105VEQ	Cold shock protein
VP_RS04945	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
VP_RS04950	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
VP_RS04960	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
VP_RS04965	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
VP_RS04970	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
VP_RS04980	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
VP_RS04985	ENOG4105RKX	Protein of unknown function (DUF2498)
VP_RS04990	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
VP_RS04995	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
VP_RS05000	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
VP_RS05020	ENOG4105HP8	regulator of competence-specific genes
VP_RS05025	ENOG4105ETE	Transcriptional regulator (LacI family
VP_RS05030	ENOG4109039	Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity)
VP_RS05035	ENOG4106WF9	DNA-binding transcriptional regulator TorR
VP_RS05040	ENOG4107S90	membrAne
VP_RS05045	ENOG4106371	Methyltransferase
VP_RS05050	ENOG4105GHU	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity (By similarity)
VP_RS05055	ENOG4105DAH	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity)
VP_RS05060	ENOG4105DUC	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division (By similarity)
VP_RS05065	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
VP_RS05075	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
VP_RS05080	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
VP_RS05085	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
VP_RS05090	ENOG41081XQ	Conserved Protein
VP_RS05095	ENOG4105C9M	aspartyl-trna synthetase
VP_RS05100	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
VP_RS05110	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
VP_RS05115	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
VP_RS05120	ENOG4105C4M	(Ubiquinol oxidase) subunit I
VP_RS05125	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
VP_RS05140	ENOG4107YD3	Thioesterase
VP_RS05145	ENOG4105E02	MotA TolQ exbB proton channel
VP_RS05150	ENOG4105M8F	Biopolymer transport protein exbD tolR
VP_RS05160	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
VP_RS05165	ENOG4105KCK	Peptidoglycan-associated lipoprotein
VP_RS05170	ENOG4105UFD	tol-pal system protein YbgF
VP_RS05175	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
VP_RS05185	ENOG4105Z6B	inner membrane protein yjfl
VP_RS05195	ENOG4106032	Glutathionylspermidine synthase
VP_RS05205	ENOG4105BZU	Histidine kinase
VP_RS05210	ENOG4108RNS	Exports L-alanine (By similarity)
VP_RS05250	ENOG4105DFP	Integrase
VP_RS05295	ENOG4105CUZ	uba thif-type nad fad binding protein
VP_RS05310	ENOG4105C8Q	Methyl-accepting chemotaxis
VP_RS05315	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
VP_RS05320	ENOG4105BZS	acriflavin resistance protein
VP_RS05350	ENOG4105FR9	TRNA-(Ms 2 io 6 A)-hydroxylase
VP_RS05360	ENOG4107R11	Transcriptional regulator
VP_RS05370	ENOG4105DCF	alanine dehydrogenase
VP_RS05375	ENOG4105EW9	transcriptional regulator AsnC family
VP_RS05380	ENOG4105CNU	cell division protein FtsK
VP_RS05385	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
VP_RS05390	ENOG4105D1H	recombination factor protein RarA
VP_RS05395	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
VP_RS05410	ENOG4105KSC	Transcriptional regulator, TraR DksA family
VP_RS05420	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
VP_RS05425	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
VP_RS05435	ENOG4105EWW	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
VP_RS05440	ENOG4105D0M	Protease HtpX homolog
VP_RS05450	ENOG4107FW0	short-chain dehydrogenase reductase
VP_RS05465	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
VP_RS05485	ENOG4107QTF	adenylosuccinate lyase
VP_RS05490	ENOG41075W9	High frequency lysogenization protein HflD homolog
VP_RS05495	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
VP_RS05505	ENOG4107RE1	Inosine-guanosine kinase
VP_RS05510	ENOG4108YX2	DNA-binding protein
VP_RS05515	ENOG4107S6Z	Na H antiporter
VP_RS05525	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
VP_RS05530	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
VP_RS05535	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
VP_RS05540	ENOG4105CIH	Imidazole acetol-phosphate transaminase
VP_RS05545	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
VP_RS05550	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
VP_RS05555	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
VP_RS05560	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
VP_RS05565	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
VP_RS05570	ENOG4105K5B	UPF0225 protein
VP_RS05575	ENOG4105D58	Diguanylate phosphodiesterase
VP_RS05580	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
VP_RS05585	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
VP_RS05590	ENOG4105C8N	cysteinyl-tRNA synthetase
VP_RS05595	ENOG4107104	thymidine kinase
VP_RS05600	ENOG4105GFG	DUF218 domain
VP_RS05625	ENOG4105TMB	Formate nitrite transporter
VP_RS05630	ENOG4105C4B	ABC transporter, permease
VP_RS05645	ENOG4108J2R	molybdopterin oxidoreductase
VP_RS05660	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
VP_RS05670	ENOG4108JQ2	peptide transport system atp-binding protein
VP_RS05675	ENOG4108JQ3	Peptide ABC transporter ATP-binding protein
VP_RS05680	ENOG4108EU3	peptide transport system, permease
VP_RS05685	ENOG4108EKA	peptide transport system, permease
VP_RS05690	ENOG4108J59	Extracellular solute-binding protein, family 5
VP_RS05695	ENOG4105E51	psp operon transcriptional activator
VP_RS05700	ENOG41087YS	Phage shock protein A
VP_RS05705	ENOG4105YYT	phage shock protein B
VP_RS05710	ENOG4105FM1	phage shock protein C
VP_RS05715	ENOG410624X	efflux transporter, rnd family, mfp subunit
VP_RS05730	ENOG4108R3E	Dna-3-methyladenine glycosylase i
VP_RS05740	ENOG4107IFA	Lipase (EC 3.1.1.3)
VP_RS05745	ENOG4105C28	cystathionine
VP_RS05750	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
VP_RS05755	ENOG4105C8J	)-transporter
VP_RS05765	ENOG4108W1A	pseudouridine synthase
VP_RS05775	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
VP_RS05780	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
VP_RS05785	ENOG4108JUA	Transcriptional regulator
VP_RS05795	ENOG4108T9J	Cdp-alcohol phosphatidyltransferase
VP_RS05800	ENOG4108VGW	abc transporter atp-binding protein
VP_RS05805	ENOG4105CXZ	ABC transporter, permease
VP_RS05810	ENOG4105VNH	ABC transporter solute-binding protein
VP_RS05815	ENOG4108RSN	SNARE associated Golgi
VP_RS05825	ENOG4105BZ8	glutamate synthase
VP_RS05835	ENOG4106AFQ	Histidine kinase
VP_RS05840	ENOG4108ZXC	Two component transcriptional regulator, luxr family
VP_RS05850	ENOG4105XZD	Fe-S protein
VP_RS05860	ENOG4105CGH	5'-nucleotidase
VP_RS05875	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
VP_RS05880	ENOG4105EB3	Histidine kinase
VP_RS05885	ENOG4105ETX	regulatoR
VP_RS05895	ENOG4105CFI	type iii restriction protein res subunit
VP_RS05900	ENOG4105I08	Pseudouridine synthase
VP_RS05905	ENOG4105C2C	drug resistance transporter, Bcr CflA
VP_RS05935	ENOG4105CUW	cytochrome C-TYPE protein
VP_RS05940	ENOG4105CGD	Nad-dependent epimerase dehydratase
VP_RS05945	ENOG4107QI1	Mate efflux family protein
VP_RS05950	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
VP_RS05965	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
VP_RS05970	ENOG41067SE	Tetr family transcriptional regulator
VP_RS05975	ENOG4107QPN	acyl-Coa dehydrogenase
VP_RS05980	ENOG4105RKW	reductase (By
VP_RS05985	ENOG4105D0C	transport protein
VP_RS05990	ENOG41090BQ	Glutaredoxin
VP_RS06000	ENOG4106KNT	transcriptional regulator
VP_RS06005	ENOG4105DY8	decarboxylase
VP_RS06015	ENOG4105DWU	Membrane
VP_RS06040	ENOG4105BZU	Histidine kinase
VP_RS06050	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
VP_RS06055	ENOG4105BZC	d-serine deaminase
VP_RS06060	ENOG4108JJ8	(ABC) transporter
VP_RS06065	ENOG4108JJ9	ABC, transporter
VP_RS06070	ENOG4105C3M	thioredoxin reductase
VP_RS06095	ENOG4105C8P	)-transporter
VP_RS06100	ENOG4107GZ4	SanA protein
VP_RS06105	ENOG4107R1I	NAD-dependent malic enzyme
VP_RS06110	ENOG4105CQ7	ATP-dependent helicase
VP_RS06115	ENOG4105HDD	phospholipase
VP_RS06130	ENOG4105C8V	SAICAR synthetase
VP_RS06150	ENOG4105CDV	Ompa motb domain protein
VP_RS06165	ENOG4105CQB	FAD linked oxidase domain protein
VP_RS06180	ENOG4105C84	Histidine ammonia-lyase
VP_RS06190	ENOG41088SP	formiminoglutamate hydrolase
VP_RS06195	ENOG4105CI2	imidazolone-5-propionate hydrolase
VP_RS06200	ENOG4105CZE	histidine utilization repressor
VP_RS06215	ENOG4105C22	threonyL-tRNA synthetase
VP_RS06220	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
VP_RS06225	ENOG41082NX	50s ribosomal protein l35
VP_RS06230	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
VP_RS06235	ENOG4105K8R	UPF0145 protein
VP_RS06265	ENOG4105BZU	Histidine kinase
VP_RS06270	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
VP_RS06275	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
VP_RS06285	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
VP_RS06295	ENOG4105FQ6	thiopurine methyltransferase
VP_RS06300	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
VP_RS06305	ENOG4107T42	This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis (By similarity)
VP_RS06310	ENOG41067MG	lrgb family
VP_RS06315	ENOG4105VAW	lrga family
VP_RS06320	ENOG4105CJB	Exodeoxyribonuclease I
VP_RS06325	ENOG4108ETY	sodium dicarboxylate symporter
VP_RS06330	ENOG4105K4T	epimerase
VP_RS06335	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
VP_RS06340	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
VP_RS06360	ENOG4107UI5	Transforms N(2)-succinylglutamate into succinate and glutamate (By similarity)
VP_RS06365	ENOG4108IU2	vtamin B12-transporter permease
VP_RS06370	ENOG41080WI	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system (By similarity)
VP_RS06390	ENOG4107RSM	transcriptional regulator
VP_RS06410	ENOG4107XDJ	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
VP_RS06420	ENOG4105KPE	licD family
VP_RS06425	ENOG4108VKG	metal-dependent hydrolase
VP_RS06430	ENOG4105EBA	Specifically methylates the adenine in position 1618 of 23S rRNA (By similarity)
VP_RS06460	ENOG4105CTU	Proline racemase
VP_RS06475	ENOG4105CIF	Ornithine Cyclodeaminase
VP_RS06480	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
VP_RS06485	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
VP_RS06490	ENOG4105F38	ABC transporter, permease
VP_RS06495	ENOG4105D38	putrescine abc transporter
VP_RS06505	ENOG4107MM9	BNR Asp-box repeat-containing protein
VP_RS06515	ENOG4108JQ7	(ABC) transporter
VP_RS06520	ENOG4105C3U	ABC transporter
VP_RS06525	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
VP_RS06530	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
VP_RS06535	ENOG4107QSI	ABC, transporter
VP_RS06540	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
VP_RS06545	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
VP_RS06550	ENOG4105F1J	Homogentisate 1,2-dioxygenase
VP_RS06560	ENOG4108RXX	maleylacetoacetate isomerase
VP_RS06605	ENOG4105Y49	secretion protein, HlyD family
VP_RS06620	ENOG4105DHJ	ABC, transporter
VP_RS06635	ENOG4105EGS	Mechanosensitive ion channel
VP_RS06640	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
VP_RS06650	ENOG4105DUM	transcriptional regulator, lysR family
VP_RS06685	ENOG4105C8P	)-transporter
VP_RS06690	ENOG4105BZU	Histidine kinase
VP_RS06695	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
VP_RS06700	ENOG4105BZU	Histidine kinase
VP_RS06705	ENOG4105CPI	Metal Dependent Phosphohydrolase
VP_RS06710	ENOG410829K	Lysine exporter protein (Lyse ygga)
VP_RS06715	ENOG4105G0K	glycine radical enzyme YjjI family
VP_RS06720	ENOG41076CZ	activating enzyme
VP_RS06730	ENOG4105EE5	Membrane protein terC
VP_RS06735	ENOG4105DR5	peptidase
VP_RS06760	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
VP_RS06765	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
VP_RS06770	ENOG4108WC9	type VI secretion system effector, hcp1 family
VP_RS06775	ENOG4105CS6	Rhs element vgr protein
VP_RS06800	ENOG4105D9P	serine threonine protein kinase
VP_RS06835	ENOG4105EW9	transcriptional regulator AsnC family
VP_RS06915	ENOG4105DHT	Metal Dependent Phosphohydrolase
VP_RS06925	ENOG4105E0U	tyrosine-specific transport protein
VP_RS06945	ENOG4105BZ1	(ABC) transporter
VP_RS06950	ENOG4105BZ1	(ABC) transporter
VP_RS06975	ENOG4105CFG	Acts as a chaperone (By similarity)
VP_RS06980	ENOG4105CFG	Acts as a chaperone (By similarity)
VP_RS06990	ENOG4105BZU	Histidine kinase
VP_RS07020	ENOG4107QY8	reductase
VP_RS07025	ENOG4105QAX	Iron-sulfur
VP_RS07030	ENOG4107KGK	dmso reductase anchor subunit
VP_RS07035	ENOG4108NEM	leader-binding protein dmsD
VP_RS07045	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
VP_RS07050	ENOG4105CQ7	ATP-dependent helicase
VP_RS07065	ENOG4105C94	Transporter
VP_RS07080	ENOG4105CND	Glycosyl transferase, family 2
VP_RS07085	ENOG4105CPK	Glycosyl transferase (Group 1
VP_RS07115	ENOG4107TYR	Glycosyl Transferase
VP_RS07125	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
VP_RS07140	ENOG4107V1M	polysaccharide export protein
VP_RS07150	ENOG41082AN	stage II sporulation protein
VP_RS07165	ENOG4107QI1	Mate efflux family protein
VP_RS07170	ENOG4108R6K	riboflavin synthase, subunit alpha
VP_RS07185	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
VP_RS07190	ENOG4105BZU	Histidine kinase
VP_RS07200	ENOG4107TT5	NLP P60 protein
VP_RS07205	ENOG4105C8Q	Methyl-accepting chemotaxis
VP_RS07240	ENOG4106IUH	DTW domain containing protein
VP_RS07245	ENOG4105EZX	Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P (By similarity)
VP_RS07255	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
VP_RS07260	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
VP_RS07265	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
VP_RS07280	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
VP_RS07285	ENOG4105BZU	Histidine kinase
VP_RS07290	ENOG4105C5H	ABC transporter
VP_RS07295	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
VP_RS07315	ENOG4109039	Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity)
VP_RS07325	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
VP_RS07330	ENOG4105QAX	Iron-sulfur
VP_RS07375	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
VP_RS07380	ENOG4107RUE	extracellular solute-binding protein family 1
VP_RS07385	ENOG4108HM4	ABC transporter
VP_RS07390	ENOG4105D38	putrescine abc transporter
VP_RS07400	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
VP_RS07420	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
VP_RS07425	ENOG4105Q9Y	Universal stress protein
VP_RS07430	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
VP_RS07445	ENOG4105C59	p-type ATPase
VP_RS07455	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
VP_RS07470	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
VP_RS07625	ENOG4105VZ1	Replication Protein
VP_RS07660	ENOG4108R9Q	Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain (By similarity)
VP_RS07665	ENOG4105DAN	ATP-dependent protease
VP_RS07670	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
VP_RS07685	ENOG4105C5H	ABC transporter
VP_RS07695	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
VP_RS07700	ENOG4108T7E	Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity)
VP_RS07705	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
VP_RS07710	ENOG4105C7I	Dehydrogenase
VP_RS07720	ENOG4105CD8	aminopeptidase N
VP_RS07730	ENOG4105CN1	protease
VP_RS07735	ENOG41073DY	may be a structural element that influences the osmotic activation of ProP at a post-translational level (By similarity)
VP_RS07740	ENOG4108ZGC	gaf domain protein
VP_RS07745	ENOG4105BZ1	(ABC) transporter
VP_RS07750	ENOG4105H2K	paraquat-inducible protein a
VP_RS07755	ENOG4105DY2	Paraquat-inducible protein b
VP_RS07760	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
VP_RS07780	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
VP_RS07785	ENOG4108VPT	UPF0234 protein
VP_RS07795	ENOG4107QXX	ABC transporter
VP_RS07800	ENOG4105EZ7	amino acid ABC transporter
VP_RS07805	ENOG4105DRP	amino acid AbC transporter
VP_RS07810	ENOG4105CDA	abc transporter atp-binding protein
VP_RS07815	ENOG4108MN8	Membrane
VP_RS07825	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
VP_RS07830	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
VP_RS07835	ENOG4105C8Q	Methyl-accepting chemotaxis
VP_RS07840	ENOG4105DR4	Methyltransferase
VP_RS07855	ENOG4105CDV	Ompa motb domain protein
VP_RS07870	ENOG4105CDV	Ompa motb domain protein
VP_RS07880	ENOG4105BZU	Histidine kinase
VP_RS07885	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
VP_RS07890	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
VP_RS07895	ENOG410667J	hydrolase
VP_RS07915	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
VP_RS07920	ENOG4105C7F	AcnD-accessory protein PrpF
VP_RS07925	ENOG4108I0Z	Aconitate hydratase
VP_RS07930	ENOG4105BZN	citrate synthase
VP_RS07935	ENOG4105CR4	methylisocitrate lyase
VP_RS07965	ENOG4105EJ9	Membrane
VP_RS08075	ENOG4105EQ2	LysR family Transcriptional regulator
VP_RS08080	ENOG4105ENX	hydrolase
VP_RS08085	ENOG4105ENX	hydrolase
VP_RS08155	ENOG41066XE	Type III export protein
VP_RS08185	ENOG4108KB1	transcriptional regulator, arac family
VP_RS08205	ENOG4105C26	Dehydrogenase
VP_RS08210	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
VP_RS08225	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
VP_RS08230	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
VP_RS08235	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
VP_RS08240	ENOG4108V9W	transcriptional regulatory protein
VP_RS08245	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
VP_RS08260	ENOG4107V40	secretion protein, HlyD family
VP_RS08275	ENOG4105CA0	peroxidase
VP_RS08280	ENOG4105CZK	Aspartate kinase
VP_RS08285	ENOG4108Z6K	Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant (By similarity)
VP_RS08290	ENOG4108JPW	Aminotransferase
VP_RS08295	ENOG4108Z24	l-2,4-diaminobutyric acid acetyltransferase
VP_RS08300	ENOG4105C94	Transporter
VP_RS08315	ENOG4108IJ7	Glycine betaine
VP_RS08320	ENOG4108HQS	Glycine betaine
VP_RS08325	ENOG4105GIJ	Glycine betaine
VP_RS08360	ENOG4105DHQ	Histidine kinase
VP_RS08365	ENOG4105E0M	Sulfatase
VP_RS08385	ENOG4105BZG	amino acid carrier protein
VP_RS08395	ENOG410829K	Lysine exporter protein (Lyse ygga)
VP_RS08400	ENOG4105CTD	carboxy-peptidase
VP_RS08405	ENOG4105D1S	lipid A biosynthesis
VP_RS08410	ENOG4105E5D	amino acid
VP_RS08420	ENOG4105CVG	Homoserine O-transsuccinylase
VP_RS08425	ENOG41090FY	type IV pilus biogenesis stability protein PilW
VP_RS08435	ENOG4105BZU	Histidine kinase
VP_RS08440	ENOG4105BZU	Histidine kinase
VP_RS08455	ENOG4108UW5	maltose o-acetyltransferase
VP_RS08475	ENOG4105MSB	protein, conserved in bacteria
VP_RS08480	ENOG4108ZT1	Transcriptional regulator
VP_RS08495	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
VP_RS08505	ENOG4105BZU	Histidine kinase
VP_RS08510	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
VP_RS08515	ENOG4108JPW	Aminotransferase
VP_RS08520	ENOG4105C26	Dehydrogenase
VP_RS08525	ENOG4105DWY	Agmatine deiminase
VP_RS08535	ENOG4105CJP	fad dependent oxidoreductase
VP_RS08545	ENOG4107VRI	Transcriptional regulator
VP_RS08550	ENOG4108Z86	Glutamine amidotransferase
VP_RS08555	ENOG4105CFQ	glutamine synthetase
VP_RS08560	ENOG4107S6Z	Na H antiporter
VP_RS08695	ENOG4108Z7R	Chaperone CsaA
VP_RS08780	ENOG4105KRQ	Addiction module toxin, Txe YoeB family
VP_RS08820	ENOG4105N82	Endonuclease
VP_RS08920	ENOG4108W2W	
VP_RS09080	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
VP_RS09100	ENOG4105D9U	N-acetyltransferase
VP_RS09110	ENOG4106K28	UPF0283 membrane protein
VP_RS09115	ENOG4105CM6	amino acid regulated cytosolic protein
VP_RS09130	ENOG4105CRQ	synthase (Component I)
VP_RS09135	ENOG4105BZU	Histidine kinase
VP_RS09145	ENOG4105P8F	nudix hydrolase
VP_RS09150	ENOG4105C44	Serine transporter
VP_RS09155	ENOG4105EJQ	L-serine dehydratase
VP_RS09160	ENOG4105BZU	Histidine kinase
VP_RS09170	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
VP_RS09185	ENOG4105VEQ	Cold shock protein
VP_RS09190	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
VP_RS09200	ENOG4108N3W	hemolysin secretion protein
VP_RS09205	ENOG4105C5S	asparaginyl-tRNA synthetase
VP_RS09215	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
VP_RS09230	ENOG4105CGF	Aromatic amino acid aminotransferase
VP_RS09250	ENOG4105C8Q	Methyl-accepting chemotaxis
VP_RS09255	ENOG4105C94	Transporter
VP_RS09260	ENOG41067TZ	transcriptional regulator, MarR family
VP_RS09275	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
VP_RS09285	ENOG4105CH5	extracellular solute-binding protein, family 7
VP_RS09300	ENOG4105C5X	domain protein
VP_RS09305	ENOG4105EAQ	(twin-arginine translocation) pathway signal
VP_RS09310	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
VP_RS09335	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
VP_RS09340	ENOG4108DMF	Cytochrome C biogenesis protein
VP_RS09345	ENOG4107QX9	Thiol disulfide interChange protein
VP_RS09350	ENOG4105DA4	cytochrome c-type biogenesis protein
VP_RS09355	ENOG4105DVI	reductase, NrfD
VP_RS09360	ENOG4105D3S	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
VP_RS09370	ENOG4105EAU	Plays a role in nitrite reduction (By similarity)
VP_RS09385	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
VP_RS09390	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
VP_RS09395	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
VP_RS09400	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
VP_RS09425	ENOG4105D3D	Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine (By similarity)
VP_RS09465	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
VP_RS09470	ENOG4105WH1	Two component transcriptional regulator luxr family
VP_RS09475	ENOG4105CQ2	DNA polymerase
VP_RS09485	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
VP_RS09490	ENOG4108W5H	UPF0263 protein
VP_RS09495	ENOG4105FE9	pseudouridine synthase
VP_RS09505	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
VP_RS09510	ENOG4105DB7	PHP domain protein
VP_RS09520	ENOG4105CRQ	synthase (Component I)
VP_RS09525	ENOG4105DDQ	anthranilate synthase
VP_RS09530	ENOG4108I0Q	anthranilate phosphoribosyltransferase
VP_RS09535	ENOG4105DK0	Indole-3-glycerol phosphate synthase
VP_RS09540	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
VP_RS09545	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
VP_RS09550	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
VP_RS09555	ENOG4105CEY	Amp-dependent synthetase and ligase
VP_RS09560	ENOG4105CK2	sodium dicarboxylate symporter
VP_RS09570	ENOG4105BZU	Histidine kinase
VP_RS09580	ENOG4107835	probably involved in intracellular septation (By similarity)
VP_RS09585	ENOG4105NAU	thioesterase Superfamily protein
VP_RS09590	ENOG4105K9H	YciI-like protein
VP_RS09600	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
VP_RS09605	ENOG4105DZ2	Transcriptional regulator
VP_RS09625	ENOG4105CCT	upf0313 protein
VP_RS09630	ENOG4105C8Q	Methyl-accepting chemotaxis
VP_RS09635	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
VP_RS09640	ENOG41062D9	Histidine kinase
VP_RS09660	ENOG4105JQN	Transcriptional regulator
VP_RS09665	ENOG4105J12	Multidrug resistance protein mdtN
VP_RS09685	ENOG4106HBX	Transcriptional Regulator AraC Family
VP_RS09690	ENOG4108W2Y	isochorismatase
VP_RS09695	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
VP_RS09700	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
VP_RS09705	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
VP_RS09715	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
VP_RS09730	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
VP_RS09745	ENOG4105N6Y	Thioredoxin
VP_RS09750	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
VP_RS09760	ENOG4105EXG	Transcriptional regulator
VP_RS09765	ENOG4108ZXC	Two component transcriptional regulator, luxr family
VP_RS09770	ENOG4106AFQ	Histidine kinase
VP_RS09775	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
VP_RS09780	ENOG4106WHD	Tetrathionate reductase
VP_RS09785	ENOG4105DB1	molybdopterin oxidoreductase
VP_RS09795	ENOG4105NQN	cytochrome C
VP_RS09800	ENOG4105F1S	paraquat-inducible protein a
VP_RS09805	ENOG4105DY2	Paraquat-inducible protein b
VP_RS09815	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
VP_RS09825	ENOG4105CKK	Glycosyl transferase, family 2
VP_RS09840	ENOG4108J59	Extracellular solute-binding protein, family 5
VP_RS09845	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
VP_RS09850	ENOG4105CFV	Tetratricopeptide repeat protein
VP_RS09855	ENOG4105Q4A	inner membrane protein yciS
VP_RS09860	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
VP_RS09865	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
VP_RS09870	ENOG4105CAT	Cytidine monophosphate kinase
VP_RS09875	ENOG4105ERU	peptidase
VP_RS09880	ENOG4105UBK	short-chain dehydrogenase reductase
VP_RS09895	ENOG4105C0B	DNA polymerase III (alpha subunit)
VP_RS09905	ENOG4105DAG	ROK family
VP_RS09910	ENOG4105CA9	Pyruvate kinase
VP_RS09915	ENOG4108NRW	Phospholipase, patatin family
VP_RS09930	ENOG4105C8J	)-transporter
VP_RS09945	ENOG4105CI1	PTS System
VP_RS09950	ENOG4105F8V	Hydrolase, tatD family
VP_RS09955	ENOG4107QRG	dna polymerase iii
VP_RS09960	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
VP_RS09965	ENOG4105HHA	aminodeoxychorismate lyase
VP_RS09975	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
VP_RS09980	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
VP_RS09985	ENOG4105CHR	reductase
VP_RS09990	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
VP_RS09995	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
VP_RS10000	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
VP_RS10005	ENOG4105VGS	50s ribosomal protein l32
VP_RS10010	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
VP_RS10015	ENOG4108UHJ	MAF-like protein
VP_RS10020	ENOG4105EI2	Pseudouridine synthase
VP_RS10025	ENOG4105C03	ribonuclease
VP_RS10030	ENOG4105CHH	sulfate transporter
VP_RS10040	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
VP_RS10050	ENOG4105DBI	uridine monophosphokinase
VP_RS10055	ENOG4105D1F	ATP-binding protein
VP_RS10060	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
VP_RS10070	ENOG4105C05	Multifunctional regulator of fatty acid metabolism (By similarity)
VP_RS10075	ENOG4105DKR	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
VP_RS10080	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
VP_RS10085	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
VP_RS10090	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
VP_RS10100	ENOG4107R28	alpha amylase, catalytic region
VP_RS10105	ENOG4108JJB	ABC transporter
VP_RS10110	ENOG4105C7J	ABC transporter, permease
VP_RS10120	ENOG4105PQ6	UPF0208 membrane protein
VP_RS10125	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
VP_RS10130	ENOG4108DNC	Involved in acetate metabolism (By similarity)
VP_RS10135	ENOG4107PU6	Membrane
VP_RS10145	ENOG4105CHF	Glutathione S-transferase
VP_RS10150	ENOG4108JQ7	(ABC) transporter
VP_RS10155	ENOG4105C3U	ABC transporter
VP_RS10160	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
VP_RS10165	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
VP_RS10170	ENOG4107QSI	ABC, transporter
VP_RS10175	ENOG4108ZAF	Molybdopterin
VP_RS10180	ENOG4105M00	molybdopterin converting factor, subunit 1
VP_RS10185	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
VP_RS10190	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
VP_RS10195	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
VP_RS10200	ENOG4105CHW	UPF0052 protein
VP_RS10210	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
VP_RS10215	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
VP_RS10225	ENOG4105DGN	Electron transport complex
VP_RS10230	ENOG4108R3D	Electron transport complex
VP_RS10240	ENOG4105D6A	Electron transport complex
VP_RS10245	ENOG4108UQQ	Electron transport complex
VP_RS10250	ENOG4105DZB	Electron transport complex
VP_RS10255	ENOG4105CSM	endonuclease III
VP_RS10260	ENOG4108UYE	Lactoylglutathione lyase
VP_RS10265	ENOG4106WH9	Protein of unknown function (DUF2753)
VP_RS10270	ENOG4105EIY	sodium-type flagellar protein motY
VP_RS10275	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
VP_RS10280	ENOG4105D3Y	Na H antiporter
VP_RS10290	ENOG4105M2J	Glutaredoxin
VP_RS10295	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
VP_RS10310	ENOG4105C0A	alcohol dehydrogenase
VP_RS10315	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
VP_RS10320	ENOG4105EYW	Ion transport protein
VP_RS10325	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
VP_RS10330	ENOG4105DFD	Na H antiporter
VP_RS10345	ENOG4106V8H	Nucleoid-associated protein
VP_RS10350	ENOG4105YDX	UPF0352 protein
VP_RS10355	ENOG4105E68	Sulfatase
VP_RS10365	ENOG4105EYG	tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site (By similarity)
VP_RS10425	ENOG4105DGU	Histone deacetylase
VP_RS10430	ENOG4108RU0	short-chain dehydrogenase reductase
VP_RS10440	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
VP_RS10445	ENOG41069NU	Nitroreductase
VP_RS10450	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
VP_RS10455	ENOG4105D07	Signal peptide peptidase, SppA
VP_RS10460	ENOG4105HDK	L-asparaginase
VP_RS10465	ENOG4105VUT	cytoplasmic protein
VP_RS10475	ENOG4105E0X	reductase
VP_RS10480	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
VP_RS10485	ENOG4105DSB	aldose 1-epimerase
VP_RS10490	ENOG4105C8Q	Methyl-accepting chemotaxis
VP_RS10495	ENOG4105DHI	Methyltransferase
VP_RS10510	ENOG4105G6Z	alkaline phosphatase
VP_RS10520	ENOG4108UYE	Lactoylglutathione lyase
VP_RS10525	ENOG41067V3	Antibiotic biosynthesis monooxygenase
VP_RS10535	ENOG4108ZZ3	UPF0260 protein
VP_RS10540	ENOG4105Y3U	Transglycosylase-associated protein
VP_RS10545	ENOG4105KRS	Proteinase inhibitor
VP_RS10555	ENOG4105CEM	UPF0597 protein
VP_RS10560	ENOG4105KME	endoribonuclease L-psp
VP_RS10565	ENOG4105C44	Serine transporter
VP_RS10570	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
VP_RS10575	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
VP_RS10580	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
VP_RS10585	ENOG4107QMP	dna polymerase iii subunits gamma and tau
VP_RS10590	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
VP_RS10595	ENOG4105WD1	Membrane
VP_RS10600	ENOG4105I93	response regulator
VP_RS10605	ENOG4105EJC	lysr family transcriptional regulator
VP_RS10610	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
VP_RS10615	ENOG4105E96	Colicin v production protein
VP_RS10620	ENOG4108S3P	Sporulation domain protein
VP_RS10625	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
VP_RS10630	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
VP_RS10635	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
VP_RS10645	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
VP_RS10650	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
VP_RS10655	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
VP_RS10660	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
VP_RS10665	ENOG4105Q8W	reductase
VP_RS10670	ENOG4105MH2	YfcL protein
VP_RS10675	ENOG4108BPE	-transporting atpase
VP_RS10680	ENOG4105EN6	Membrane
VP_RS10685	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
VP_RS10690	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
VP_RS10695	ENOG4108DG9	Smr protein MutS2
VP_RS10700	ENOG4108BY2	phosphohistidine phosphatase
VP_RS10705	ENOG4107QXK	peptidase
VP_RS10715	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
VP_RS10720	ENOG4105CHU	acetyl-coa acetyltransferase
VP_RS10735	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
VP_RS10740	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
VP_RS10745	ENOG410903C	(LipO)protein
VP_RS10755	ENOG4108M1T	Cytochrome c-type biogenesis protein
VP_RS10760	ENOG4107QX9	Thiol disulfide interChange protein
VP_RS10765	ENOG4105DA4	cytochrome c-type biogenesis protein
VP_RS10770	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
VP_RS10775	ENOG4105X3C	heme exporter protein
VP_RS10780	ENOG41060IM	Heme exporter protein
VP_RS10785	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
VP_RS10790	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
VP_RS10800	ENOG4108V3W	Chemotaxis protein, CheW
VP_RS10810	ENOG4107QJE	Chromosome Partitioning Protein
VP_RS10815	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
VP_RS10825	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
VP_RS10830	ENOG4108VYJ	response regulator receiver protein
VP_RS10835	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
VP_RS10845	ENOG4105FZW	flagellar biosynthesis regulator FlhF
VP_RS10850	ENOG4105D7B	Flagellar biosynthesis protein flha
VP_RS10855	ENOG4105D00	flagellar biosynthetic protein flhB
VP_RS10860	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
VP_RS10865	ENOG4105VS8	Flagellar biosynthetic protein fliq
VP_RS10870	ENOG4105CN7	Flagellar biosynthetic protein FliP
VP_RS10875	ENOG4105VTB	flagellar biosynthesis protein fliO
VP_RS10880	ENOG4105DD5	Flagellar motor switch protein
VP_RS10885	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
VP_RS10905	ENOG4108JIR	Flagellum-specific ATP synthase
VP_RS10915	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
VP_RS10920	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
VP_RS10925	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
VP_RS10935	ENOG4105BZU	Histidine kinase
VP_RS10945	ENOG4105MQ3	flagellar protein FliS
VP_RS10955	ENOG4107BRV	flagellar capping protein
VP_RS10960	ENOG41063QE	flagellar protein FlaG
VP_RS10965	ENOG4105I03	Flagellin
VP_RS10970	ENOG4105I03	Flagellin
VP_RS10975	ENOG4105I03	Flagellin
VP_RS10980	ENOG4105EZR	dyp-type peroxidase family protein
VP_RS10985	ENOG4105QZU	Inner membrane protein YfeZ
VP_RS11005	ENOG4105KUZ	arsenate reductase
VP_RS11010	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
VP_RS11025	ENOG4107EG0	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
VP_RS11035	ENOG4105RH4	Glycine cleavage system transcriptional repressor
VP_RS11040	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
VP_RS11055	ENOG4105ERG	peptidase m48, ste24p
VP_RS11060	ENOG4105K89	arsenate reductase
VP_RS11065	ENOG4105CS1	NAD(P)H quinone oxidoreductase
VP_RS11080	ENOG4105C2W	permease
VP_RS11085	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
VP_RS11090	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
VP_RS11095	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
VP_RS11100	ENOG4105E7A	Glutamine amidotransferase
VP_RS11105	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
VP_RS11110	ENOG4107QPN	acyl-Coa dehydrogenase
VP_RS11125	ENOG4107RZZ	dna polymerase iii epsilon subunit
VP_RS11130	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
VP_RS11135	ENOG4105D1A	Methyltransferase
VP_RS11140	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
VP_RS11145	ENOG4105E9H	Lytic Murein transglycosylase
VP_RS11155	ENOG4107NA1	Endonuclease Exonuclease phosphatase
VP_RS11160	ENOG4108YZA	Nitrogen regulatory protein pii
VP_RS11170	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
VP_RS11175	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
VP_RS11180	ENOG4105C0B	DNA polymerase III (alpha subunit)
VP_RS11190	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
VP_RS11195	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
VP_RS11200	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
VP_RS11205	ENOG4108RFI	Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity)
VP_RS11215	ENOG4105DZP	Membrane-associated zinc metalloprotease
VP_RS11220	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
VP_RS11225	ENOG4105KNE	Phosphatidate cytidylyltransferase
VP_RS11230	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
VP_RS11235	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
VP_RS11240	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
VP_RS11245	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
VP_RS11250	ENOG4105CE9	30S ribosomal protein S2
VP_RS11255	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
VP_RS11260	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
VP_RS11265	ENOG4108T8E	UPF0325 protein
VP_RS11270	ENOG4105DR9	pseudouridine synthase
VP_RS11275	ENOG4105WP7	tRNA pseudouridine synthase C
VP_RS11300	ENOG4108UPT	UPF0178 protein
VP_RS11305	ENOG4105CFC	Transporter
VP_RS11315	ENOG4105NRA	50s ribosomal protein l31 type b
VP_RS11320	ENOG4108R96	Methyltransferase, YaeB family
VP_RS11325	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
VP_RS11335	ENOG4105W1I	UPF0253 protein
VP_RS11345	ENOG4105C8J	)-transporter
VP_RS11360	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
VP_RS11365	ENOG4105C9U	ATP-dependent DNA helicase RecQ
VP_RS11370	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
VP_RS11385	ENOG4105CJ2	(LipO)protein
VP_RS11390	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
VP_RS11395	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
VP_RS11400	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
VP_RS11405	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
VP_RS11410	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
VP_RS11415	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
VP_RS11420	ENOG4105M85	Bola protein
VP_RS11425	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
VP_RS11430	ENOG4105IEY	(LipO)protein
VP_RS11435	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
VP_RS11450	ENOG4105K6V	RNA polymerase
VP_RS11470	ENOG4105DRB	nucleoside-specific channel-forming protein
VP_RS11475	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
VP_RS11480	ENOG4107S0N	DJ-1 family
VP_RS11485	ENOG4105C9B	Cysteine desulfurase
VP_RS11490	ENOG4105BZU	Histidine kinase
VP_RS11495	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
VP_RS11500	ENOG4105CUZ	uba thif-type nad fad binding protein
VP_RS11505	ENOG4105CA3	membrane-bound lytic murein transglycosylase
VP_RS11515	ENOG4107QZM	n-acetylglutamate synthase
VP_RS11525	ENOG4107QYX	exodeoxyribonuclease v alpha
VP_RS11530	ENOG4107QKA	exodeoxyribonuclease V beta
VP_RS11535	ENOG4105DSY	exodeoxyribonuclease V, gamma
VP_RS11540	ENOG4105E68	Sulfatase
VP_RS11550	ENOG4105EVZ	LysR family transcriptional regulator
VP_RS11555	ENOG4105X2V	dna damage-inducible protein
VP_RS11560	ENOG4105EJ3	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity)
VP_RS11565	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
VP_RS11570	ENOG4105CXY	transporter
VP_RS11575	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
VP_RS11580	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
VP_RS11585	ENOG4105E98	transcriptional regulator DeoR family
VP_RS11590	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
VP_RS11595	ENOG4107RX3	Mg2 transporter protein cora family protein
VP_RS11610	ENOG4108Y51	tRNA-binding protein
VP_RS11615	ENOG41060NJ	transcriptional regulator
VP_RS11620	ENOG4105CT4	transporter
VP_RS11630	ENOG4107KJX	Transcriptional regulator
VP_RS11635	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
VP_RS11640	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
VP_RS11645	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
VP_RS11650	ENOG4105CMR	udp-glucose 4-epimerase
VP_RS11655	ENOG4105CQ4	Transcriptional regulator
VP_RS11660	ENOG4105CNT	hydrolase family 2
VP_RS11665	ENOG4105FK9	beta-D-galactosidase beta subunit
VP_RS11675	ENOG41064T2	transcriptional regulator, lysR family
VP_RS11760	ENOG4108IQE	Amp-dependent synthetase and ligase
VP_RS11770	ENOG4105ETT	transcriptional Regulator, LysR family
VP_RS11775	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
VP_RS11780	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
VP_RS11790	ENOG4105EAC	phosphoserine phosphatase
VP_RS11800	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
VP_RS11805	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
VP_RS11810	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
VP_RS11815	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
VP_RS11820	ENOG4105D9N	nucleoside
VP_RS11825	ENOG4105EYA	deoxyribonuclease
VP_RS11835	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
VP_RS11855	ENOG4108YYD	acetyltransferase
VP_RS11865	ENOG4105BZU	Histidine kinase
VP_RS11880	ENOG4105C3S	Mate efflux family protein
VP_RS11895	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
VP_RS11900	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
VP_RS11905	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
VP_RS11910	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
VP_RS11915	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
VP_RS11920	ENOG4105CHV	Transcription elongation factor NusA
VP_RS11925	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
VP_RS11940	ENOG4105NTZ	Preprotein translocase subunit SecG
VP_RS11945	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
VP_RS11950	ENOG4105EEI	dihydropteroate synthase
VP_RS11955	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
VP_RS11960	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
VP_RS11965	ENOG4105HBR	Rna-binding protein
VP_RS11970	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
VP_RS11975	ENOG4107QE9	Inherit from COG: Membrane
VP_RS11980	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
VP_RS11990	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
VP_RS11995	ENOG4105DR5	peptidase
VP_RS12000	ENOG4105BZS	acriflavin resistance protein
VP_RS12010	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
VP_RS12015	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
VP_RS12020	ENOG4105IPI	Membrane
VP_RS12025	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
VP_RS12030	ENOG4105BZU	Histidine kinase
VP_RS12035	ENOG4107QRA	Extracellular solute-binding protein, family 5
VP_RS12045	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
VP_RS12050	ENOG4105C3U	ABC transporter
VP_RS12055	ENOG4108JQ7	(ABC) transporter
VP_RS12065	ENOG4105RD7	BadF BadG BcrA BcrD
VP_RS12070	ENOG4105E2D	ec 3.2.1.52
VP_RS12085	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
VP_RS12105	ENOG4108YZA	Nitrogen regulatory protein pii
VP_RS12110	ENOG4105XTV	UPF0231 protein
VP_RS12115	ENOG4107QIJ	Aconitate hydratase 2
VP_RS12120	ENOG4105D78	K07001 NTE family protein
VP_RS12125	ENOG4105BZ4	penicillin-binding protein
VP_RS12130	ENOG4105CQ7	ATP-dependent helicase
VP_RS12135	ENOG4105PW4	Sugar fermentation stimulation protein homolog
VP_RS12140	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
VP_RS12145	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
VP_RS12150	ENOG4105DJ0	Poly(A) Polymerase
VP_RS12155	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
VP_RS12160	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
VP_RS12165	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
VP_RS12170	ENOG4105D1S	lipid A biosynthesis
VP_RS12175	ENOG4105E3A	(ABC) transporter
VP_RS12180	ENOG4105DA5	(ABC) transporter
VP_RS12185	ENOG4105CHH	sulfate transporter
VP_RS12190	ENOG41077A9	carbonic anhydrase
VP_RS12195	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
VP_RS12200	ENOG410630P	Transcriptional regulator
VP_RS12205	ENOG4107QN2	dihydrolipoyl dehydrogenase
VP_RS12210	ENOG4107QSN	dihydrolipoamide acetyltransferase
VP_RS12215	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
VP_RS12220	ENOG41073TP	transcriptional regulator
VP_RS12230	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
VP_RS12235	ENOG4105X0D	Fimbrial protein
VP_RS12240	ENOG4107QHF	type ii secretion system protein e
VP_RS12245	ENOG4105D7Q	type ii secretion system
VP_RS12250	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
VP_RS12255	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
VP_RS12260	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
VP_RS12265	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
VP_RS12270	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
VP_RS12275	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
VP_RS12280	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
VP_RS12285	ENOG4105K5M	30s ribosomal protein S16
VP_RS12290	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
VP_RS12295	ENOG4106KVJ	cytochrome C assembly protein
VP_RS12300	ENOG4108JU6	CBS domain protein
VP_RS12305	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
VP_RS12315	ENOG4105D9M	gamma-glutamylcysteine synthetase
VP_RS12325	ENOG4105W39	Membrane
VP_RS12330	ENOG4105CPQ	Dehydrogenase
VP_RS12335	ENOG4105D9Q	decarboxylase (Beta subunit)
VP_RS12340	ENOG4107QSA	Oxaloacetate decarboxylase
VP_RS12345	ENOG4106AFN	Lyase and sodium transporter (By similarity)
VP_RS12395	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
VP_RS12400	ENOG4105CFH	Aspartokinase
VP_RS12405	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
VP_RS12410	ENOG4105Y3E	Modulates RecA activity (By similarity)
VP_RS12415	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
VP_RS12420	ENOG4107TH8	cina domain protein
VP_RS12425	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
VP_RS12440	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
VP_RS12445	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
VP_RS12450	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
VP_RS12455	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
VP_RS12460	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
VP_RS12465	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
VP_RS12470	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
VP_RS12475	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
VP_RS12480	ENOG4105DXN	mazG family
VP_RS12485	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
VP_RS12490	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
VP_RS12495	ENOG4105BZU	Histidine kinase
VP_RS12500	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
VP_RS12505	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
VP_RS12510	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
VP_RS12515	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
VP_RS12520	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
VP_RS12525	ENOG4105C3F	Signal peptidase i
VP_RS12530	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
VP_RS12545	ENOG41069PW	sigma-e factor negative regulatory protein
VP_RS12550	ENOG4105EMN	RNA polymerase sigma factor
VP_RS12555	ENOG4108IYU	L-aspartate oxidase
VP_RS12560	ENOG4105Y75	tpr repeat protein
VP_RS12565	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
VP_RS12580	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
VP_RS12585	ENOG4105D0A	hydroxylase
VP_RS12595	ENOG4107YUN	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
VP_RS12605	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
VP_RS12610	ENOG4105E66	phosphoriboisomerase A
VP_RS12615	ENOG4108JQ1	Dehydrogenase
VP_RS12620	ENOG4105MPN	Membrane
VP_RS12625	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
VP_RS12635	ENOG4108KXH	Ybak prolyl-tRNA synthetase associated
VP_RS12640	ENOG4105D64	Mechanosensitive ion channel
VP_RS12645	ENOG4105D2N	Aldolase
VP_RS12650	ENOG4105BZA	Phosphoglycerate kinase
VP_RS12655	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
VP_RS12660	ENOG4105D05	Receptor
VP_RS12665	ENOG4108R4R	Iron-regulated virulence regulatory protein
VP_RS12670	ENOG4105CV1	Transketolase (EC 2.2.1.1)
VP_RS12675	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
VP_RS12685	ENOG4105GPY	SprT protein
VP_RS12690	ENOG4105RWS	endonuclease I
VP_RS12695	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
VP_RS12700	ENOG4105D7Z	glutathione synthase
VP_RS12705	ENOG4108UJU	UPF0301 protein
VP_RS12710	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
VP_RS12715	ENOG4105CZX	twitching motility protein
VP_RS12720	ENOG4105CZX	twitching motility protein
VP_RS12725	ENOG4105DFA	alanine racemase domain protein
VP_RS12730	ENOG4105II7	pyrroline-5-carboxylate reductase
VP_RS12735	ENOG4108VIA	integral membrane protein
VP_RS12740	ENOG4105VZ9	UPF0235 protein
VP_RS12750	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
VP_RS12755	ENOG4105CSA	Coproporphyrinogen iii oxidase
VP_RS12760	ENOG4105CSV	Glutaminase
VP_RS12770	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
VP_RS12775	ENOG4105CEN	a g-specific adenine glycosylase
VP_RS12780	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
VP_RS12785	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
VP_RS12825	ENOG4105C8Q	Methyl-accepting chemotaxis
VP_RS12855	ENOG4105C26	Dehydrogenase
VP_RS12900	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
VP_RS12910	ENOG410901P	UPF0249 protein
VP_RS12915	ENOG4105F8D	glycoside hydrolase family 4
VP_RS12920	ENOG4105VCP	PTS System
VP_RS12925	ENOG4105CK1	PTS System
VP_RS12930	ENOG4105VZJ	PTS System
VP_RS12945	ENOG4107JEE	Short-chain dehydrogenase reductase Sdr
VP_RS12960	ENOG4108K5H	permease YjgP YjgQ family protein
VP_RS12965	ENOG4108M8S	permease YjgP YjgQ family protein
VP_RS12970	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
VP_RS12975	ENOG4105MYG	DNA polymerase iii, chi subunit
VP_RS12980	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
VP_RS12990	ENOG4108MJ3	acetyltransferase
VP_RS13005	ENOG4105CEU	Arginine dihydrolase
VP_RS13010	ENOG4105DBV	ornithine carbamoyltransferase
VP_RS13020	ENOG4105CXT	aspartate transcarbamylase
VP_RS13025	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
VP_RS13030	ENOG4105KME	endoribonuclease L-psp
VP_RS13035	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
VP_RS13040	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
VP_RS13045	ENOG4105VFK	BolA family
VP_RS13055	ENOG4105E3I	toluene tolerance
VP_RS13060	ENOG4107PE3	Mammalian cell entry related domain protein
VP_RS13065	ENOG4105CY3	ABC transporter, permease
VP_RS13070	ENOG4105DHJ	ABC, transporter
VP_RS13080	ENOG4105C2X	Arabinose 5-phosphate isomerase
VP_RS13090	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
VP_RS13095	ENOG4108IUZ	ABC transporter
VP_RS13100	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
VP_RS13105	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
VP_RS13110	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
VP_RS13115	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
VP_RS13120	ENOG41080Z8	PHOSPHOCARRIER protein
VP_RS13125	ENOG4105CJW	magnesium transporter
VP_RS13130	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
VP_RS13135	ENOG4105N42	UPF0307 protein
VP_RS13140	ENOG4105C5I	Dehydrogenase
VP_RS13145	ENOG4105D3G	Pseudouridine synthase
VP_RS13150	ENOG4105K3M	)-transporter
VP_RS13155	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
VP_RS13160	ENOG4108IAB	Phoh family
VP_RS13165	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
VP_RS13175	ENOG4105QD6	exported protein
VP_RS13180	ENOG4105C03	ribonuclease
VP_RS13185	ENOG4108Z03	MAF-like protein
VP_RS13190	ENOG4105VQ7	Rod shape-determining protein MreD
VP_RS13195	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
VP_RS13245	ENOG4105D7Q	type ii secretion system
VP_RS13250	ENOG4107QHF	type ii secretion system protein e
VP_RS13265	ENOG4105E4G	Type IV pilus
VP_RS13285	ENOG41062P1	Diguanylate cyclase phosphodiesterase
VP_RS13290	ENOG4108UUM	single-stranded DNA-binding protein
VP_RS13295	ENOG41086KC	Transcriptional regulator
VP_RS13300	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
VP_RS13305	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
VP_RS13315	ENOG4105C5R	Aminotransferase
VP_RS13320	ENOG4105CFH	Aspartokinase
VP_RS13325	ENOG4105C3R	Methionine synthase
VP_RS13330	ENOG4105EEQ	Na H antiporter
VP_RS13365	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
VP_RS13370	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
VP_RS13375	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
VP_RS13395	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
VP_RS13400	ENOG4105MYN	Zinc uptake regulation protein
VP_RS13410	ENOG4107QP8	phosphohexose isomerase
VP_RS13415	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
VP_RS13430	ENOG4105CDU	Replicative dna helicase
VP_RS13440	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
VP_RS13445	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
VP_RS13450	ENOG4108VDV	Binds single-stranded DNA at the primosome assembly site (PAS) (By similarity)
VP_RS13455	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
VP_RS13460	ENOG4105DJV	ribulose-phosphate 3-epimerase
VP_RS13465	ENOG4105DFE	Dna adenine methylase
VP_RS13475	ENOG4105D49	3-dehydroquinate synthase
VP_RS13480	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
VP_RS13485	ENOG4105E4G	Type IV pilus
VP_RS13510	ENOG4108JQC	penicillin-binding protein 1A
VP_RS13520	ENOG4105EHV	domain protein
VP_RS13530	ENOG4105CH7	arginosuccinase
VP_RS13535	ENOG4105CDH	Citrulline--aspartate ligase
VP_RS13540	ENOG4105CAS	nag kinase
VP_RS13545	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
VP_RS13550	ENOG4105CWC	Acetylornithine deacetylase
VP_RS13555	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
VP_RS13565	ENOG4105SYT	Methylenetetrahydrofolate reductase
VP_RS13570	ENOG4105CFH	Aspartokinase
VP_RS13575	ENOG4105C28	cystathionine
VP_RS13580	ENOG4105GGQ	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity)
VP_RS13585	ENOG4105C6K	Malic enzyme
VP_RS13590	ENOG4108UQY	Iron-storage protein
VP_RS13595	ENOG4105W53	bacterioferritin-associated ferredoxin
VP_RS13600	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
VP_RS13605	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
VP_RS13610	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
VP_RS13615	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
VP_RS13620	ENOG4105YKK	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
VP_RS13625	ENOG4108ZKU	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
VP_RS13630	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
VP_RS13635	ENOG4105WWK	YheO domain protein
VP_RS13640	ENOG4108V1T	peptidylprolyl cis-trans isomerase
VP_RS13650	ENOG41069P5	Protein slyX homolog
VP_RS13655	ENOG4105D44	asparaginase
VP_RS13660	ENOG4108YZY	peptidylprolyl cis-trans isomerase
VP_RS13675	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
VP_RS13680	ENOG4105C5H	ABC transporter
VP_RS13690	ENOG4105DNZ	Alpha Beta Hydrolase
VP_RS13695	ENOG4105YP7	UPF0270 protein
VP_RS13700	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
VP_RS13715	ENOG4105C26	Dehydrogenase
VP_RS13725	ENOG4105C8Y	Acetylornithine aminotransferase
VP_RS13730	ENOG4105DDQ	anthranilate synthase
VP_RS13745	ENOG4105C31	Tryptophanyl-tRNA synthetase
VP_RS13750	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
VP_RS13755	ENOG4105C2N	RNA methyltransferase TrmH family group 3
VP_RS13760	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
VP_RS13765	ENOG4105KPV	Transcriptional regulator
VP_RS13770	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
VP_RS13775	ENOG4108UV7	flagellar protein motX
VP_RS13780	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
VP_RS13790	ENOG4105EPW	hflc protein
VP_RS13795	ENOG4107QJR	hflk protein
VP_RS13800	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
VP_RS13805	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
VP_RS13810	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
VP_RS13815	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
VP_RS13820	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
VP_RS13825	ENOG4105K8N	protein family UPF0079, ATPase
VP_RS13830	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
VP_RS13900	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
VP_RS13905	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
VP_RS13910	ENOG4105DJ4	phosphatidylserine decarboxylase
VP_RS13915	ENOG4105C8P	)-transporter
VP_RS13920	ENOG4108NVR	Methyl-accepting chemotaxis
VP_RS13930	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
VP_RS13935	ENOG4107YZP	Rhodanese domain protein
VP_RS13940	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
VP_RS13945	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
VP_RS13950	ENOG4105D7W	serine acetyltransferase
VP_RS13955	ENOG41063SB	peptidase
VP_RS13965	ENOG41062JF	Transcriptional regulator
VP_RS13975	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
VP_RS13985	ENOG4105E33	succinate dehydrogenase
VP_RS13990	ENOG4108WJH	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
VP_RS13995	ENOG4108VP9	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
VP_RS14005	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
VP_RS14010	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
VP_RS14015	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
VP_RS14030	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
VP_RS14035	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
VP_RS14045	ENOG4105CTQ	phosphohexokinase
VP_RS14050	ENOG41076HS	cation diffusion facilitator family transporter
VP_RS14055	ENOG4108SPG	Periplasmic Protein
VP_RS14060	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
VP_RS14065	ENOG4105E0F	Histidine kinase
VP_RS14075	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
VP_RS14080	ENOG4108YH1	overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7
VP_RS14085	ENOG4108IJ0	Aspartate ammonia-lyase
VP_RS14090	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
VP_RS14095	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
VP_RS14105	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
VP_RS14115	ENOG4107QN1	sodium solute
VP_RS14130	ENOG4105C9Q	fumarate hydratase class II
VP_RS14135	ENOG4105BZU	Histidine kinase
VP_RS14140	ENOG4105D8G	Major Facilitator superfamily
VP_RS14155	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
VP_RS14160	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
VP_RS14165	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
VP_RS14170	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
VP_RS14175	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
VP_RS14180	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
VP_RS14185	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
VP_RS14190	ENOG4107XZQ	multidrug resistance protein
VP_RS14195	ENOG4105C5H	ABC transporter
VP_RS14200	ENOG4105BZU	Histidine kinase
VP_RS14270	ENOG4105CXN	decarboxylase
VP_RS14275	ENOG4105D5Q	Arginine ornithine antiporter
VP_RS14285	ENOG4108M3R	transcriptional activator CadC
VP_RS14290	ENOG4105W1Y	Transcriptional regulator
VP_RS14295	ENOG4105DC1	bifunctional purine biosynthesis protein purh
VP_RS14300	ENOG4105C12	Phosphoribosylglycinamide synthetase
VP_RS14370	ENOG4105R2J	Conserved Protein
VP_RS14375	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
VP_RS14380	ENOG4108RG0	uracil-dna glycosylase
VP_RS14385	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
VP_RS14400	ENOG4105E09	nadh pyrophosphatase
VP_RS14405	ENOG4108ZVW	Anti-RNA polymerase sigma 70 factor
VP_RS14410	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
VP_RS14415	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
VP_RS14420	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
VP_RS14425	ENOG4108VZM	50s ribosomal protein L10
VP_RS14430	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
VP_RS14435	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
VP_RS14440	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
VP_RS14445	ENOG4105PM1	preprotein translocase subunit SecE
VP_RS14450	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
VP_RS14475	ENOG4105CS9	pantothenic acid kinase
VP_RS14480	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
VP_RS14485	ENOG4105D4A	Cell wall formation (By similarity)
VP_RS14495	ENOG4105JIM	Phosphatidylserine synthase
VP_RS14540	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
VP_RS14550	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
VP_RS14555	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
VP_RS14570	ENOG4105DX1	Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity)
VP_RS14575	ENOG4107R73	Mate efflux family protein
VP_RS14585	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
VP_RS14590	ENOG4105E55	glycerol-3-phosphate acyltransferase
VP_RS14595	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
VP_RS14600	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
VP_RS14605	ENOG4105X6C	Flagellar basal body-associated protein FliL
VP_RS14610	ENOG4105EBW	Rhomboid-type serine protease that catalyzes intramembrane proteolysis (By similarity)
VP_RS14615	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
VP_RS14620	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
VP_RS14625	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
VP_RS14630	ENOG4105CAK	Cell division ATP-binding protein ftsE
VP_RS14635	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
VP_RS14640	ENOG4106H78	methyltransferase
VP_RS14650	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
VP_RS14700	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
VP_RS14705	ENOG41082YX	Transcriptional regulator, arsr family
VP_RS14710	ENOG4105D58	Diguanylate phosphodiesterase
VP_RS14715	ENOG410829K	Lysine exporter protein (Lyse ygga)
VP_RS14720	ENOG4108EUD	Lysophospholipase
VP_RS14725	ENOG4105DQF	Hydrolase
VP_RS14740	ENOG4106IUH	DTW domain containing protein
VP_RS14745	ENOG4105BZU	Histidine kinase
VP_RS14750	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
VP_RS14755	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
VP_RS14765	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
VP_RS14770	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
VP_RS14780	ENOG4105XQ6	frataxin-like protein
VP_RS14785	ENOG4107T0K	Adenylate cyclase
VP_RS14790	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
VP_RS14795	ENOG41076E6	Uroporphyrinogen-III Synthase
VP_RS14800	ENOG4105ECF	c-methyltransferase
VP_RS14805	ENOG410601J	HemY protein
VP_RS14840	ENOG4107QK7	reductase
VP_RS14845	ENOG4108ZIT	Ferredoxin, 2FE-2S
VP_RS14850	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
VP_RS14860	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
VP_RS14870	ENOG4105C1J	atp-dependent rna helicase
VP_RS14875	ENOG4105C9X	ppx gppa phosphatase
VP_RS14880	ENOG4105EX9	Membrane
VP_RS14890	ENOG4105C9U	ATP-dependent DNA helicase RecQ
VP_RS14895	ENOG4105FR1	rard protein
VP_RS14905	ENOG4105CCF	Lysine exporter protein (Lyse ygga)
VP_RS14910	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
VP_RS14915	ENOG4105C4R	Atp-dependent dna helicase
VP_RS14925	ENOG4105E18	UPF0276 protein
VP_RS14955	ENOG4105DC7	peptidase M24
VP_RS14955	ENOG4105DC7	peptidase M24
VP_RS14960	ENOG4105D41	biosynthesis protein thiH
VP_RS14965	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
VP_RS14970	ENOG4105WHD	thiamine biosynthesis protein ThiS
VP_RS14975	ENOG4105D06	uba thif-type nad fad binding protein
VP_RS14980	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
VP_RS14985	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
VP_RS14990	ENOG4105WMR	Protein CrcB homolog
VP_RS15035	ENOG4108Z0R	Transferase
VP_RS15040	ENOG4105SG3	Protein of unknown function (DUF1488)
VP_RS15045	ENOG4105E2X	shikimate dehydrogenase
VP_RS15050	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
VP_RS15055	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
VP_RS15060	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
VP_RS15065	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
VP_RS15070	ENOG4108WI1	Dna topoisomerase
VP_RS15075	ENOG4108RPN	Protein smg homolog
VP_RS15080	ENOG4105C79	DNA protecting protein DprA
VP_RS15095	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
VP_RS15100	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
VP_RS15105	ENOG4105C1A	potassium transporter peripheral membrane
VP_RS15110	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
VP_RS15120	ENOG4108UT2	hemolysin iii
VP_RS15125	ENOG4108N23	SpoOM-related protein
VP_RS15130	ENOG4105PC1	Conserved Protein
VP_RS15140	ENOG4105E27	serine threonine protein kinase
VP_RS15145	ENOG4108Z33	Thiol disulfide Interchange Protein
VP_RS15150	ENOG4106HNH	Acyl-transferase
VP_RS15160	ENOG4105C0P	Mg chelatase subunit ChlI
VP_RS15170	ENOG4105P3Y	Acetolactate synthase 2 regulatory subunit
VP_RS15175	ENOG4105CM2	brancheD-chain amino acid aminotransferase
VP_RS15180	ENOG4105C01	Dihydroxy-acid dehydratase
VP_RS15185	ENOG4105C7B	Threonine dehydratase
VP_RS15190	ENOG4105F52	Transcriptional regulator
VP_RS15195	ENOG4105CZQ	inner membrane transport protein YdhC
VP_RS15205	ENOG4105EAD	ABC transporter
VP_RS15210	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
VP_RS15215	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
VP_RS15220	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
VP_RS15225	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
VP_RS15230	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
VP_RS15235	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
VP_RS15240	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
VP_RS15245	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
VP_RS15250	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
VP_RS15255	ENOG410684E	atp synthase
VP_RS15260	ENOG4105FA0	parb-like partition protein
VP_RS15265	ENOG4107QJE	Chromosome Partitioning Protein
VP_RS15270	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
VP_RS15275	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
VP_RS15290	ENOG4108JQ7	(ABC) transporter
VP_RS15315	ENOG4105BZU	Histidine kinase
VP_RS15325	ENOG4105CDY	transcriptional regulatory protein
VP_RS15330	ENOG4105CNI	cell division protein FtsW
VP_RS15340	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
VP_RS15360	ENOG4108HRK	Histidine kinase
VP_RS15365	ENOG4108VAC	response regulator
VP_RS15375	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
VP_RS15380	ENOG4105C8Q	Methyl-accepting chemotaxis
VP_RS15400	ENOG4105D6U	Sodium Glutamate Symporter
VP_RS15410	ENOG4105DVE	abc transporter atp-binding protein
VP_RS15415	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
VP_RS15420	ENOG4105D6U	Sodium Glutamate Symporter
VP_RS15430	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
VP_RS15450	ENOG4105C2I	pirin domain protein
VP_RS15455	ENOG4108VGI	doxx family
VP_RS15465	ENOG4105D03	DNA-3-methyladenine glycosylase II
VP_RS15470	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
VP_RS15490	ENOG4105DN9	Na H antiporter
VP_RS15520	ENOG4105NBK	UPF0345 protein
VP_RS15530	ENOG4108K0B	C-di-gmp phosphodiesterase
VP_RS15535	ENOG4105UQX	Mate efflux family protein
VP_RS15540	ENOG4105D3G	Pseudouridine synthase
VP_RS15555	ENOG4105EJC	lysr family transcriptional regulator
VP_RS15560	ENOG4108HCJ	Hydrolase
VP_RS15570	ENOG4108KHX	Diguanylate cyclase
VP_RS15590	ENOG4108MUX	N-hydroxyarylamine O-acetyltransferase
VP_RS15595	ENOG4105CC0	LysR family Transcriptional regulator
VP_RS15610	ENOG4105J4Q	Transcriptional regulator
VP_RS15615	ENOG4105CHR	reductase
VP_RS15620	ENOG4105P66	Membrane
VP_RS15625	ENOG4105M5J	Cupin 2, conserved barrel domain protein
VP_RS15640	ENOG4107SS6	2-dehydro-3-deoxygluconokinase
VP_RS15645	ENOG4108UHU	Aldolase
VP_RS15670	ENOG4105CAZ	oligogalacturonide lyase
VP_RS15675	ENOG4105Q26	Siderophore-interacting protein
VP_RS15685	ENOG4105EW9	transcriptional regulator AsnC family
VP_RS15690	ENOG4108M1A	Chitin-binding protein
VP_RS15705	ENOG4107W31	Pentapeptide repeat protein
VP_RS15710	ENOG4105EIF	outer membrane protein W
VP_RS15720	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
VP_RS15740	ENOG4107WCA	isomerase
VP_RS15745	ENOG4108UVJ	appr-1-p processing domain protein
VP_RS15750	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
VP_RS15755	ENOG4108WAV	Transcriptional regulator
VP_RS15780	ENOG4108YZS	Had-superfamily hydrolase, subfamily ia, variant 1
VP_RS15800	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
VP_RS15805	ENOG4105C6Z	Gluconate
VP_RS15810	ENOG4105BZW	Glycerate kinase
VP_RS15815	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
VP_RS15850	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
VP_RS15860	ENOG4105CUW	cytochrome C-TYPE protein
VP_RS15865	ENOG4107QY8	reductase
VP_RS15875	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
VP_RS15880	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
VP_RS15885	ENOG4105ETU	transcriptional activator (TenA
VP_RS15890	ENOG4107Z6I	Thiamine biosynthesis protein
VP_RS15895	ENOG4105Y36	Binding-protein-dependent transport systems, inner membrane component
VP_RS15900	ENOG4108YI8	ABC transporter
VP_RS15905	ENOG4105DWF	phosphomethylpyrimidine kinase
VP_RS15920	ENOG4108TEM	pseudouridine methyltransferase
VP_RS15970	ENOG4108YYI	Protein of unknown function (DUF2810)
VP_RS15975	ENOG4105C5I	Dehydrogenase
VP_RS15985	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
VP_RS15995	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
VP_RS16000	ENOG410804D	Sensor Signal Transduction Histidine Kinase
VP_RS16025	ENOG4109015	Biopolymer transport protein exbD tolR
VP_RS16065	ENOG4105DSE	periplasmic solute binding protein
VP_RS16070	ENOG4105DIK	(ABC) transporter
VP_RS16075	ENOG4105CC5	ABC transporter
VP_RS16090	ENOG4105CUG	Oligopeptidase b
VP_RS16095	ENOG4105E5M	Multidrug resistance protein D
VP_RS16100	ENOG4105CYW	agmatinase
VP_RS16105	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
VP_RS16115	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
VP_RS16120	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
VP_RS16125	ENOG4105DUM	transcriptional regulator, lysR family
VP_RS16155	ENOG4105CQZ	Histidine kinase
VP_RS16160	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
VP_RS16165	ENOG4105BZU	Histidine kinase
VP_RS16170	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
VP_RS16185	ENOG4105D5U	fad dependent oxidoreductase
VP_RS16195	ENOG4105C0F	tryptophanase EC 4.1.99.1
VP_RS16210	ENOG4105D9N	nucleoside
VP_RS16225	ENOG4105BZU	Histidine kinase
VP_RS16230	ENOG4108N3W	hemolysin secretion protein
VP_RS16245	ENOG4106TD9	Diguanylate cyclase
VP_RS16250	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
VP_RS16255	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
VP_RS16270	ENOG4105E0X	reductase
VP_RS16275	ENOG4108UKZ	OsmC family
VP_RS16280	ENOG4108UW5	maltose o-acetyltransferase
VP_RS16315	ENOG4105JQN	Transcriptional regulator
VP_RS16320	ENOG4105PAD	Hydrolase
VP_RS16335	ENOG4108UUE	Transcriptional regulator
VP_RS16345	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
VP_RS16350	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
VP_RS16355	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
VP_RS16365	ENOG4105KUU	lipolytic protein G-D-S-L family
VP_RS16395	ENOG4105ETE	Transcriptional regulator (LacI family
VP_RS16400	ENOG4108KAZ	Involved in phosphonate degradation (By similarity)
VP_RS16405	ENOG4108JPW	Aminotransferase
VP_RS16410	ENOG4107STF	Involved in phosphonate degradation (By similarity)
VP_RS16430	ENOG4107RCV	ABC transporter, permease
VP_RS16450	ENOG4108MJ5	VirK protein
VP_RS16455	ENOG4105CJP	fad dependent oxidoreductase
VP_RS16470	ENOG4105ETT	transcriptional Regulator, LysR family
VP_RS16490	ENOG4105DUX	Transporter
VP_RS16495	ENOG4105EJQ	L-serine dehydratase
VP_RS16515	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
VP_RS16520	ENOG4105E4C	Lytic transglycosylase catalytic
VP_RS16540	ENOG4105Q75	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
VP_RS16545	ENOG4108ZC9	flagellar basal-body rod protein flgc
VP_RS16550	ENOG4105W00	Flagellar hook capping protein
VP_RS16555	ENOG4105BZE	flagellar hook protein, FlgE
VP_RS16560	ENOG4108KPB	Flagellar basal-body rod protein FlgF
VP_RS16565	ENOG4105CGA	flagellar basal-body rod protein FlgG
VP_RS16570	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
VP_RS16575	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
VP_RS16580	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
VP_RS16585	ENOG4105E1Q	flagellar hook-associated protein
VP_RS16590	ENOG4105DTJ	flagellar hook-associated protein
VP_RS16610	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
VP_RS16635	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
VP_RS16640	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
VP_RS16645	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
VP_RS16660	ENOG4105N14	lysine exporter protein LysE YggA
VP_RS16680	ENOG4107Z3H	Transcriptional regulator, TetR family
VP_RS16690	ENOG4105CGH	5'-nucleotidase
VP_RS16695	ENOG4105EA8	2-Nitropropane dioxygenase
VP_RS16700	ENOG4105DM4	PTS System
VP_RS16710	ENOG4105G2Y	Transcriptional regulator
VP_RS16720	ENOG4108F19	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
VP_RS16725	ENOG4105KHA	Glyoxalase Bleomycin resistance protein (Dioxygenase
VP_RS16730	ENOG4105N2W	Transcriptional regulator
VP_RS16740	ENOG4105CH6	catalase
VP_RS16750	ENOG4108RWI	nicotinamidase
VP_RS16760	ENOG4107RH7	Nicotinate phosphoribosyltransferase
VP_RS16785	ENOG4105ETT	transcriptional Regulator, LysR family
VP_RS16800	ENOG4105RW8	MltA-interacting MipA family protein
VP_RS16805	ENOG4107EII	Lipoprotein involved with copper homeostasis and adhesion
VP_RS16810	ENOG4105VYW	UPF0251 protein
VP_RS16835	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
VP_RS16840	ENOG4107S8C	mandelate racemase muconate lactonizing
VP_RS16850	ENOG4105RQF	LysR family Transcriptional regulator
VP_RS16860	ENOG4108Z4X	TRANSCRIPTIONal
VP_RS16885	ENOG4107RZC	phospholipase d
VP_RS16920	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
VP_RS16960	ENOG41086KC	Transcriptional regulator
VP_RS16970	ENOG4105BZU	Histidine kinase
VP_RS16990	ENOG4107V40	secretion protein, HlyD family
VP_RS17005	ENOG4108HM4	ABC transporter
VP_RS17010	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
VP_RS17025	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
VP_RS17030	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
VP_RS17035	ENOG4105HDK	L-asparaginase
VP_RS17040	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
VP_RS17060	ENOG4105IUQ	nucleoprotein polynucleotide-associated enzyme
VP_RS17065	ENOG4108ZX5	transcriptional regulator
VP_RS17070	ENOG4105CHR	reductase
VP_RS17080	ENOG4105CPQ	Dehydrogenase
VP_RS17085	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
VP_RS17100	ENOG4107RSM	transcriptional regulator
VP_RS17110	ENOG4105C1J	atp-dependent rna helicase
VP_RS17150	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
VP_RS17155	ENOG410874W	AraC family transcriptional regulator
VP_RS17185	ENOG4105CKW	Inner membrane protein yedI
VP_RS17190	ENOG4105EKE	dihydroorotase
VP_RS17200	ENOG4105QVC	MOSC domain-containing protein
VP_RS17200	ENOG4105QVC	MOSC domain-containing protein
VP_RS17205	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
VP_RS17210	ENOG4107X4V	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
VP_RS17250	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
VP_RS17255	ENOG4105EHG	Permease protein
VP_RS17265	ENOG4106GFD	transport protein
VP_RS17270	ENOG41090AP	transport protein
VP_RS17275	ENOG4105WQ5	TonB family
VP_RS17280	ENOG4105D4P	Coproporphyrinogen iii oxidase
VP_RS17285	ENOG41090JE	Utilization Protein
VP_RS17290	ENOG4105PYN	Pyridoxamine 5-phosphate oxidase-related
VP_RS17305	ENOG4105KQ5	peptidylprolyl cis-trans isomerase
VP_RS17310	ENOG4107TII	Recombinase
VP_RS17335	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
VP_RS17405	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
VP_RS17415	ENOG4105C5Q	Transcriptional regulator
VP_RS17430	ENOG4105KXC	Collagenase
VP_RS17455	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
VP_RS17460	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
VP_RS17465	ENOG4108M6U	Universal stress protein A
VP_RS17470	ENOG4105C5H	ABC transporter
VP_RS17485	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
VP_RS17495	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
VP_RS17505	ENOG4108HK0	-acetyltransferase
VP_RS17510	ENOG410620I	Diguanylate cyclase
VP_RS17535	ENOG4108IJF	Heavy metal efflux pump, CzcA
VP_RS17555	ENOG4108IEG	Formate dehydrogenase Alpha subunit
VP_RS17570	ENOG4107QWP	ABC-2 type transporter
VP_RS17575	ENOG4105CJ1	ABC, transporter
VP_RS17585	ENOG4108NVR	Methyl-accepting chemotaxis
VP_RS17590	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
VP_RS17595	ENOG4105JAB	phenazine biosynthesis protein, phzf family
VP_RS17600	ENOG4108V1U	phospholipid-binding protein
VP_RS17610	ENOG4105D6J	arsenicaL-resistance protein
VP_RS17625	ENOG4108X7Y	Mannitol-specific cryptic phosphotransferase enzyme iia
VP_RS17630	ENOG4105CTS	PTS system mannitol-specific
VP_RS17635	ENOG4105DXH	Alcohol dehydrogenase zinc-binding domain protein
VP_RS17645	ENOG4107Z1W	Fructose transport system kinase
VP_RS17670	ENOG4105E0U	tyrosine-specific transport protein
VP_RS17680	ENOG4105C8Q	Methyl-accepting chemotaxis
VP_RS17685	ENOG4105DWD	nucleoside recognition domain protein
VP_RS17705	ENOG4105DR5	peptidase
VP_RS17715	ENOG4105CR8	Transcriptional regulator
VP_RS17720	ENOG4105E5M	Multidrug resistance protein D
VP_RS17735	ENOG4108SXK	Transporter Drug Metabolite Exporter family
VP_RS17740	ENOG4105FCK	Membrane
VP_RS17765	ENOG4105SUT	Transcriptional Regulator AraC Family
VP_RS17770	ENOG4105CCF	Lysine exporter protein (Lyse ygga)
VP_RS17795	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
VP_RS17800	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
VP_RS17820	ENOG4107TQK	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
VP_RS17825	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
VP_RS17830	ENOG4108V1T	peptidylprolyl cis-trans isomerase
VP_RS17860	ENOG4105VEQ	Cold shock protein
VP_RS17870	ENOG4107SDU	Methyl-accepting chemotaxis
VP_RS17875	ENOG4105BZU	Histidine kinase
VP_RS17895	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
VP_RS17905	ENOG4105C8Q	Methyl-accepting chemotaxis
VP_RS17910	ENOG4108RMU	ferritin dps family protein
VP_RS17925	ENOG4105C0A	alcohol dehydrogenase
VP_RS17930	ENOG4108556	Isoprenoid biosynthesis protein with amidotransferase-like domain
VP_RS17965	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
VP_RS17970	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
VP_RS17975	ENOG4105MIR	Phenylalanine 4-monooxygenase
VP_RS17980	ENOG41090A4	Pterin carbinolamine dehydratase
VP_RS18000	ENOG4105VRT	cytoplasmic protein
VP_RS18005	ENOG4105C1J	atp-dependent rna helicase
VP_RS18010	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
VP_RS18015	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
VP_RS18025	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
VP_RS18035	ENOG4105CKI	cobalamin synthesis protein
VP_RS18040	ENOG4105C1J	atp-dependent rna helicase
VP_RS18060	ENOG4105CXC	rtn protein
VP_RS18065	ENOG4105DKW	ABC transporter
VP_RS18070	ENOG4108N3W	hemolysin secretion protein
VP_RS18075	ENOG4105DUM	transcriptional regulator, lysR family
VP_RS18080	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
VP_RS18085	ENOG4105C4X	radical SAM domain protein
VP_RS18105	ENOG4107S17	Phosphate-binding protein
VP_RS18120	ENOG4108ENQ	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction (By similarity)
VP_RS18125	ENOG4105C1J	atp-dependent rna helicase
VP_RS18130	ENOG4105BZU	Histidine kinase
VP_RS18135	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
VP_RS18140	ENOG4107SDU	Methyl-accepting chemotaxis
VP_RS18155	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
VP_RS18160	ENOG4105CGU	Enoyl-CoA hydratase
VP_RS18165	ENOG4107QX3	carboxylase
VP_RS18170	ENOG4105C1G	acyl-Coa dehydrogenase
VP_RS18180	ENOG4105CHU	acetyl-coa acetyltransferase
VP_RS18185	ENOG4105C26	Dehydrogenase
VP_RS18195	ENOG4105E39	Enoyl-CoA hydratase
VP_RS18200	ENOG4105E39	Enoyl-CoA hydratase
VP_RS18205	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
VP_RS18210	ENOG4105CHR	reductase
VP_RS18215	ENOG4105E2S	oxidase) subunit II
VP_RS18220	ENOG4105BZ9	Cytochrome C oxidase, subunit I
VP_RS18225	ENOG4105CCU	oxidase (Subunit III)
VP_RS18235	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
VP_RS18245	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
VP_RS18255	ENOG4105E5Z	arginine transporter ATP-binding subunit
VP_RS18260	ENOG4106PMH	Extracellular solute-binding protein family 3
VP_RS18265	ENOG4105GBT	ABC transporter
VP_RS18270	ENOG4105DMR	ABC, transporter
VP_RS18280	ENOG4105DUM	transcriptional regulator, lysR family
VP_RS18285	ENOG4107MKT	Stringent starvation protein a
VP_RS18290	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
VP_RS18295	ENOG4107QSN	dihydrolipoamide acetyltransferase
VP_RS18300	ENOG4105CPP	Dehydrogenase, E1 component
VP_RS18305	ENOG4107RUY	(E1 component), alpha subunit
VP_RS18320	ENOG4105R8A	Heat shock protein
VP_RS18325	ENOG4106E5D	Protein of unknown function (DUF461)
VP_RS18350	ENOG4105DHS	permease protein
VP_RS18355	ENOG4105CM4	permease protein
VP_RS18360	ENOG4108IPW	abc transporter atp-binding protein
VP_RS18365	ENOG4108Z6Z	Transcriptional regulator
VP_RS18405	ENOG4105EM2	membrane
VP_RS18410	ENOG41088T4	Helicase IV
VP_RS18415	ENOG4108Z5K	methylglyoxal synthase
VP_RS18420	ENOG4108SV3	Tmao reductase system periplasmic protein tort
VP_RS18425	ENOG4105BZU	Histidine kinase
VP_RS18440	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
VP_RS18445	ENOG41061MV	Arylsulfatase
VP_RS18450	ENOG4105ENH	Sulfatase
VP_RS18465	ENOG4105ENH	Sulfatase
VP_RS18470	ENOG4105C4X	radical SAM domain protein
VP_RS18475	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
VP_RS18505	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
VP_RS18510	ENOG41064T2	transcriptional regulator, lysR family
VP_RS18515	ENOG4107TE5	Lipid kinase
VP_RS18520	ENOG4108YDI	single-species biofilm formation on inanimate substrate
VP_RS18535	ENOG4105C4X	radical SAM domain protein
VP_RS18545	ENOG4105F2V	VRR-NUC domain-containing protein
VP_RS18560	ENOG4105D0M	Protease HtpX homolog
VP_RS18565	ENOG4108V0P	LemA family
VP_RS18570	ENOG4105CEE	C4-dicarboxylate transporter
VP_RS18590	ENOG4108MGY	Histidine kinase
VP_RS18595	ENOG4107KBT	8-Amino-7-oxononanoate synthase
VP_RS18600	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
VP_RS18610	ENOG4105KXC	Collagenase
VP_RS18620	ENOG4106R3P	AraC family transcriptional regulator
VP_RS18695	ENOG4105CDV	Ompa motb domain protein
VP_RS18705	ENOG4108WAV	Transcriptional regulator
VP_RS18710	ENOG41064T2	transcriptional regulator, lysR family
VP_RS18720	ENOG4105BZU	Histidine kinase
VP_RS18725	ENOG4105BZU	Histidine kinase
VP_RS18730	ENOG4108WQH	regulatoR
VP_RS18735	ENOG4105BZU	Histidine kinase
VP_RS18745	ENOG4108WQH	regulatoR
VP_RS18760	ENOG4107R88	Chemotaxis protein (CheV)
VP_RS18765	ENOG4108VAU	general secretion pathway protein G
VP_RS18775	ENOG4105FR1	rard protein
VP_RS18785	ENOG4106CKV	Pap2 superfamily protein
VP_RS18805	ENOG4108I0N	Transporter, RarD family, DMT superfamily protein
VP_RS18825	ENOG4107RGH	Aldehyde dehydrogenase
VP_RS18830	ENOG4107QPK	)-transporter
VP_RS18835	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
VP_RS18840	ENOG4106YYS	transcriptional regulatory protein
VP_RS18855	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
VP_RS18880	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
VP_RS18885	ENOG4108UYE	Lactoylglutathione lyase
VP_RS18905	ENOG4105CJW	magnesium transporter
VP_RS18935	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
VP_RS18950	ENOG4105HDD	phospholipase
VP_RS18975	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
VP_RS18980	ENOG4105CR8	Transcriptional regulator
VP_RS18990	ENOG4105C5W	Aldolase
VP_RS19015	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
VP_RS19020	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
VP_RS19025	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
VP_RS19045	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
VP_RS19065	ENOG4105DM4	PTS System
VP_RS19070	ENOG4105DE4	1-phosphofructokinase
VP_RS19075	ENOG4105DTZ	bifunctional PTS system fructose-specific transporter subunit IIA HPr protein
VP_RS19080	ENOG4107B7Y	DNA-binding transcriptional regulator FruR
VP_RS19095	ENOG4108NJZ	Sensory box GGDEF EAL domain protein
VP_RS19100	ENOG4105DRP	amino acid AbC transporter
VP_RS19105	ENOG4106TNF	Periplasmic binding protein
VP_RS19110	ENOG4105E5Q	amino acid AbC transporter
VP_RS19115	ENOG4105CDA	abc transporter atp-binding protein
VP_RS19120	ENOG4105CA9	Pyruvate kinase
VP_RS19125	ENOG4105CXY	transporter
VP_RS19130	ENOG4106JDA	Phosphoglycerate transport regulatory protein PGTC
VP_RS19140	ENOG4107TXD	phosphoglycerate transport system transcriptional regulatory protein pgta
VP_RS19150	ENOG4108I6A	alcohol dehydrogenase
VP_RS19155	ENOG4105CF7	AraC family transcriptional regulator
VP_RS19165	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
VP_RS19170	ENOG4105CKU	formyltetrahydrofolate synthetase
VP_RS19175	ENOG4107RE1	Inosine-guanosine kinase
VP_RS19190	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
VP_RS19195	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
VP_RS19205	ENOG4108ZYK	Acyl carrier protein phosphodiesterase
VP_RS19210	ENOG4105C1J	atp-dependent rna helicase
VP_RS19215	ENOG4108M8H	domain protein
VP_RS19230	ENOG4105DS1	cytochrome b561
VP_RS19235	ENOG4108YYC	ycei family
VP_RS19240	ENOG4105TMB	Formate nitrite transporter
VP_RS19245	ENOG4105DUM	transcriptional regulator, lysR family
VP_RS19250	ENOG4108UQ5	membrane protein YcdZ
VP_RS19255	ENOG4105CPB	ATP-dependent endonuclease of the OLD family
VP_RS19260	ENOG4105CGH	5'-nucleotidase
VP_RS19265	ENOG4105DU1	integral membrane protein, terc
VP_RS19280	ENOG4108M0H	Extracellular lipase
VP_RS19285	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
VP_RS19300	ENOG4105KA0	thioesterase Superfamily protein
VP_RS19335	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
VP_RS19345	ENOG4105BZU	Histidine kinase
VP_RS19350	ENOG4105RKW	reductase (By
VP_RS19360	ENOG4108I0Y	(ABC) transporter
VP_RS19365	ENOG4105CV6	ABC transporter, permease
VP_RS19370	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
VP_RS19375	ENOG4107R7A	Allophanate hydrolase subunit 2
VP_RS19380	ENOG4105P4J	Allophanate hydrolase, subunit 1
VP_RS19385	ENOG4105E7W	lamb ycsf family protein
VP_RS19390	ENOG4105BZU	Histidine kinase
VP_RS19395	ENOG4105CMR	udp-glucose 4-epimerase
VP_RS19405	ENOG4105CWB	LysR family transcriptional Regulator
VP_RS19410	ENOG4105CD5	CoA-binding domain protein
VP_RS19420	ENOG4105CPF	Cell wall formation (By similarity)
VP_RS19430	ENOG4108ZJT	translation initiation factor, Sui1
VP_RS19515	ENOG4105VZ1	Replication Protein
VP_RS19545	ENOG4105EJC	lysr family transcriptional regulator
VP_RS19555	ENOG4108M6U	Universal stress protein A
VP_RS19585	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
VP_RS19590	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
VP_RS19625	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
VP_RS19630	ENOG4105E0C	molybdate abc transporter
VP_RS19635	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
VP_RS19640	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
VP_RS19645	ENOG4105WXI	Bacterial OB fold (BOF) protein
VP_RS19655	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
VP_RS19660	ENOG4105CGF	Aromatic amino acid aminotransferase
VP_RS19665	ENOG4105ECQ	AraC Family Transcriptional Regulator
VP_RS19670	ENOG4107QI1	Mate efflux family protein
VP_RS19675	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
VP_RS19680	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
VP_RS19695	ENOG4105BZS	acriflavin resistance protein
VP_RS19760	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
VP_RS19765	ENOG4105C5Q	Transcriptional regulator
VP_RS19770	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
VP_RS19775	ENOG4105CXY	transporter
VP_RS19780	ENOG4108KX4	response regulator
VP_RS19785	ENOG4105BZU	Histidine kinase
VP_RS19790	ENOG4105CXY	transporter
VP_RS19795	ENOG4105EIP	mannose-6-phosphate isomerase
VP_RS19815	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
VP_RS19820	ENOG4105K63	Thioredoxin
VP_RS19835	ENOG4107QI1	Mate efflux family protein
VP_RS19840	ENOG4105VXR	cytoplasmic protein
VP_RS19865	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
VP_RS19880	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
VP_RS19885	ENOG4105TMB	Formate nitrite transporter
VP_RS19890	ENOG4105WZK	nitrite reductase NADPH small subunit
VP_RS19895	ENOG4107QZF	nitrite reductase NADPH large subunit
VP_RS19900	ENOG4105NXH	GreA GreB family elongation factor
VP_RS19935	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
VP_RS19970	ENOG4108NVR	Methyl-accepting chemotaxis
VP_RS19975	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
VP_RS19990	ENOG4105CXG	d-lactate dehydrogenase
VP_RS19995	ENOG4105CC0	LysR family Transcriptional regulator
VP_RS20010	ENOG4105EV2	VWA domain protein interacting with AAA ATPase
VP_RS20015	ENOG4107R4Q	Functions as an ATPase. May play a role in metal insertion (metal-chelatase) or as a chaperone (By similarity)
VP_RS20025	ENOG4105C5W	Aldolase
VP_RS20030	ENOG4106RE7	Cytochrome
VP_RS20035	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
VP_RS20045	ENOG4105C2C	drug resistance transporter, Bcr CflA
VP_RS20055	ENOG4105QNF	Outer membrane lipoprotein
VP_RS20075	ENOG4105EYH	Exonuclease
VP_RS20080	ENOG4107RFY	SbcCD D subunit
VP_RS20105	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
VP_RS20150	ENOG4108ZF3	Phosphatase
VP_RS20165	ENOG4106VK6	Flagellar motor protein
VP_RS20185	ENOG4105D9P	serine threonine protein kinase
VP_RS20210	ENOG4105F8J	Adenylate Guanylate cyclase
VP_RS20225	ENOG4108IG5	Transcriptional regulator
VP_RS20240	ENOG4107QZF	nitrite reductase NADPH large subunit
VP_RS20245	ENOG4105D7T	ABC transporter
VP_RS20250	ENOG4105DG7	nitrate ABC transporter
VP_RS20275	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
VP_RS20290	ENOG4105C44	Serine transporter
VP_RS20315	ENOG4105G6Z	alkaline phosphatase
VP_RS20330	ENOG4105ETX	regulatoR
VP_RS20350	ENOG4108I5U	Uridine phosphorylase
VP_RS20355	ENOG4106Z1T	Nicotinamide Mononucleotide Transporter
VP_RS20360	ENOG4105ETE	Transcriptional regulator (LacI family
VP_RS20365	ENOG4108RVA	ribokinase
VP_RS20370	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
VP_RS20375	ENOG4105CNN	ABC, transporter
VP_RS20380	ENOG4105C2J	ABC transporter
VP_RS20385	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
VP_RS20390	ENOG4108K0B	C-di-gmp phosphodiesterase
VP_RS20395	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
VP_RS20450	ENOG4105BZU	Histidine kinase
VP_RS20455	ENOG4105CA0	peroxidase
VP_RS20460	ENOG4105BZU	Histidine kinase
VP_RS20470	ENOG4107QX8	SPFH domain, Band 7 family protein
VP_RS20480	ENOG4108RCM	Nitroreductase
VP_RS20485	ENOG4108IJ7	Glycine betaine
VP_RS20490	ENOG4108HQS	Glycine betaine
VP_RS20500	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
VP_RS20505	ENOG4105C26	Dehydrogenase
VP_RS20510	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
VP_RS20515	ENOG4105BZU	Histidine kinase
VP_RS20520	ENOG4105CHR	reductase
VP_RS20525	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
VP_RS20535	ENOG4105E39	Enoyl-CoA hydratase
VP_RS20540	ENOG4105C1G	acyl-Coa dehydrogenase
VP_RS20545	ENOG4105C26	Dehydrogenase
VP_RS20550	ENOG4105CHU	acetyl-coa acetyltransferase
VP_RS20560	ENOG4105C1G	acyl-Coa dehydrogenase
VP_RS20565	ENOG4107QX3	carboxylase
VP_RS20570	ENOG4108IPT	Naphthoate synthase
VP_RS20580	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
VP_RS20585	ENOG4105BZU	Histidine kinase
VP_RS20600	ENOG4105EGS	Mechanosensitive ion channel
VP_RS20605	ENOG4108UW5	maltose o-acetyltransferase
VP_RS20610	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
VP_RS20615	ENOG4105C4M	(Ubiquinol oxidase) subunit I
VP_RS20620	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
VP_RS20630	ENOG4108S58	Phenazine biosynthesis protein PhzF
VP_RS20635	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
VP_RS20640	ENOG4105VUF	Transcriptional regulator
VP_RS20650	ENOG4105G9V	cytochrome C
VP_RS20665	ENOG4105DZS	Phenylacetate-CoA ligase
VP_RS20670	ENOG4108IV0	ABC, transporter
VP_RS20695	ENOG4105C0Z	ABC transporter
VP_RS20700	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
VP_RS20705	ENOG4105BZJ	Electron transfer flavoprotein
VP_RS20710	ENOG4105C10	Electron transfer flavoprotein
VP_RS20715	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
VP_RS20720	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
VP_RS20725	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
VP_RS20735	ENOG4108UNF	response regulator
VP_RS20740	ENOG4107RGM	aldo keto reductase
VP_RS20755	ENOG4105CMQ	Chloride channel
VP_RS20765	ENOG4105C5A	transporter
VP_RS20775	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
VP_RS20780	ENOG4105D06	uba thif-type nad fad binding protein
VP_RS20795	ENOG4105KHC	sulfurtransferase
VP_RS20800	ENOG4105BZU	Histidine kinase
VP_RS20815	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
VP_RS20820	ENOG4105CV1	Transketolase (EC 2.2.1.1)
VP_RS20825	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
VP_RS20830	ENOG4105DXI	Major Facilitator superfamily
VP_RS20835	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
VP_RS20840	ENOG4105UYK	outer membrane protein a
VP_RS20845	ENOG4107VXZ	Hydrolase
VP_RS20850	ENOG4108YZN	class I peptide chain release factor
VP_RS20855	ENOG4108N3W	hemolysin secretion protein
VP_RS20870	ENOG4107YWA	deoxycytidylate deaminase
VP_RS20875	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
VP_RS20890	ENOG4105WH1	Two component transcriptional regulator luxr family
VP_RS20895	ENOG4105BZU	Histidine kinase
VP_RS20910	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
VP_RS20920	ENOG4105CUW	cytochrome C-TYPE protein
VP_RS20930	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
VP_RS20940	ENOG4105CHU	acetyl-coa acetyltransferase
VP_RS20950	ENOG410829K	Lysine exporter protein (Lyse ygga)
VP_RS20960	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
VP_RS20965	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
VP_RS21010	ENOG4105EFX	secretion protein, HlyD family
VP_RS21020	ENOG4105BZU	Histidine kinase
VP_RS21025	ENOG4108QGH	periplasmic
VP_RS21030	ENOG41082IR	Excinuclease ABC C subunit domain protein
VP_RS21035	ENOG4108YXG	UPF0502 protein
VP_RS21045	ENOG41090HJ	UPF0265 protein
VP_RS21055	ENOG4105EE0	oxidoreductase
VP_RS21060	ENOG4105BZU	Histidine kinase
VP_RS21085	ENOG4108XM1	transcriptional regulator AsnC family
VP_RS21090	ENOG4105DVH	amino acid
VP_RS21105	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
VP_RS21110	ENOG4105CJW	magnesium transporter
VP_RS21115	ENOG4105DQW	permease for cytosine purines, uracil, thiamine, allantoin
VP_RS21120	ENOG4105DZC	cytosine deaminase
VP_RS21130	ENOG4105EST	Metal Dependent Phosphohydrolase
VP_RS21140	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
VP_RS21150	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
VP_RS21170	ENOG4105EQR	Transposase IS116 IS110 IS902
VP_RS21220	ENOG4108MA7	Inherit from COG: YD repeat protein
VP_RS21235	ENOG4105C7H	Helicase, RecD TraA family
VP_RS21260	ENOG4108Z33	Thiol disulfide Interchange Protein
VP_RS21275	ENOG4105EMU	Dehydrogenase
VP_RS21280	ENOG4107EXC	regulatoR
VP_RS21285	ENOG4105JJR	Histidine kinase
VP_RS21295	ENOG41080IJ	Diacylglycerol kinase
VP_RS21300	ENOG4105DIJ	Phosphoethanolamine transferase
VP_RS21305	ENOG4105EP9	oxidoreductase
VP_RS21325	ENOG4108T3F	Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes
VP_RS21335	ENOG4108NRW	Phospholipase, patatin family
VP_RS21345	ENOG4105VEQ	Cold shock protein
VP_RS21360	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
VP_RS21380	ENOG4105DZ1	carboxypeptidase
VP_RS21385	ENOG4105CYM	Glutathione S-transferase
VP_RS21395	ENOG4105NAE	bifunctional deaminase-reductase domain protein
VP_RS21415	ENOG4105CHR	reductase
VP_RS21430	ENOG4108P3C	
VP_RS21510	ENOG41066DG	(EAL) domain protein
VP_RS21595	ENOG41075IY	surface presentation of antigens protein SpaP
VP_RS21620	ENOG4108TU9	TRANSCRIPTIONal
VP_RS21645	ENOG4105UYK	outer membrane protein a
VP_RS21745	ENOG4105F88	accessory colonization factor AcfD
VP_RS21850	ENOG4105EG2	ABC transporter, permease
VP_RS21855	ENOG4105D56	permease protein
VP_RS21860	ENOG4107FKK	extracellular solute-binding protein family 1
VP_RS21865	ENOG4108IJ9	(ABC) transporter
VP_RS21925	ENOG4105V0I	UPF0267 protein
VP_RS21930	ENOG4108WUH	Transcriptional regulator, TetR family
VP_RS21935	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
VP_RS21940	ENOG4108RXX	maleylacetoacetate isomerase
VP_RS21945	ENOG4105CH6	catalase
VP_RS21950	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
VP_RS21955	ENOG4105DM4	PTS System
VP_RS21960	ENOG4108YRF	PTS System
VP_RS21970	ENOG4106R3P	AraC family transcriptional regulator
VP_RS21975	ENOG4105DM4	PTS System
VP_RS21980	ENOG4105EIP	mannose-6-phosphate isomerase
VP_RS21990	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
VP_RS22000	ENOG4105BZU	Histidine kinase
VP_RS22005	ENOG4105CZN	Potassium uptake protein
VP_RS22025	ENOG4105BZ1	(ABC) transporter
VP_RS22030	ENOG4105E0K	tonB-dependent siderophore receptor
VP_RS22035	ENOG4105E0A	ABC, transporter
VP_RS22040	ENOG4108HUF	Transporter
VP_RS22045	ENOG4105S6R	Iron-hydroxamate transporter permease subunit
VP_RS22055	ENOG4105KCK	Peptidoglycan-associated lipoprotein
VP_RS22075	ENOG4108JJ6	Type I secretion system ATPase
VP_RS22085	ENOG41086KC	Transcriptional regulator
VP_RS22090	ENOG41086KC	Transcriptional regulator
VP_RS22100	ENOG41069D7	Methyl-accepting chemotaxis
VP_RS22105	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
VP_RS22125	ENOG4107QVM	von Willebrand factor, type A
VP_RS22140	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
VP_RS22145	ENOG4105E2Z	phosphate ABC transporter (Permease
VP_RS22150	ENOG4105C8U	phosphate abc transporter
VP_RS22160	ENOG4108NVR	Methyl-accepting chemotaxis
VP_RS22180	ENOG4105D05	Receptor
VP_RS22185	ENOG4105CUG	Oligopeptidase b
VP_RS22190	ENOG4105C1J	atp-dependent rna helicase
VP_RS22200	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
VP_RS22205	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
VP_RS22210	ENOG4108XDN	Transcriptional regulator
VP_RS22215	ENOG4107SEY	Conserved Protein
VP_RS22220	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
VP_RS22235	ENOG4106TD9	Diguanylate cyclase
VP_RS22240	ENOG4105KK7	inner membrane protein YiaW
VP_RS22245	ENOG4105EFX	secretion protein, HlyD family
VP_RS22250	ENOG4108V7D	UPF0397 protein
VP_RS22255	ENOG4108JJB	ABC transporter
VP_RS22270	ENOG4105GXZ	Ferredoxin-type protein NapH
VP_RS22275	ENOG4108BGM	Quinol dehydrogenase periplasmic component
VP_RS22280	ENOG4105WCN	acetyltransferase
VP_RS22295	ENOG4105YE1	PilZ domain
VP_RS22300	ENOG4108NVR	Methyl-accepting chemotaxis
VP_RS22305	ENOG4105DAN	ATP-dependent protease
VP_RS22315	ENOG4108JQ5	ABC transporter
VP_RS22325	ENOG4105CR8	Transcriptional regulator
VP_RS22330	ENOG4105DAA	L-lactate
VP_RS22335	ENOG4105DMF	Dehydrogenase
VP_RS22345	ENOG4105D64	Mechanosensitive ion channel
VP_RS22380	ENOG4105CPQ	Dehydrogenase
VP_RS22385	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
VP_RS22390	ENOG4105BZU	Histidine kinase
VP_RS22395	ENOG4107R0W	ABC transporter
VP_RS22405	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
VP_RS22415	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
VP_RS22435	ENOG4105EXG	Transcriptional regulator
VP_RS22440	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
VP_RS22460	ENOG4107SSZ	Phosphatase
VP_RS22490	ENOG4108JIR	Flagellum-specific ATP synthase
VP_RS22500	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
VP_RS22505	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
VP_RS22530	ENOG4105DD5	Flagellar motor switch protein
VP_RS22535	ENOG4105CN7	Flagellar biosynthetic protein FliP
VP_RS22540	ENOG4105VS8	Flagellar biosynthetic protein fliq
VP_RS22545	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
VP_RS22550	ENOG4105D00	flagellar biosynthetic protein flhB
VP_RS22565	ENOG4105I03	Flagellin
VP_RS22575	ENOG410804A	Flagellar hook-associated 2 domain-containing protein
VP_RS22580	ENOG4105MQ3	flagellar protein FliS
VP_RS22605	ENOG4107RD7	Flagellar Motor Protein, MotA
VP_RS22610	ENOG4105ER2	Ompa motb domain protein
VP_RS22620	ENOG4105KWG	Pfam:DUF1696
VP_RS22660	ENOG4105F1A	Pyruvate formate-lyase
VP_RS22665	ENOG4107T9Z	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
VP_RS22675	ENOG4105I4A	GCN5-related N-acetyltransferase
VP_RS22690	ENOG4105CNH	Multidrug resistance protein MdtL
VP_RS22695	ENOG4105G2Y	Transcriptional regulator
VP_RS22730	ENOG4105IPI	Membrane
VP_RS22735	ENOG41068P6	UPF0319 protein
VP_RS22745	ENOG4105DP0	ferredoxin-NADP reductase
VP_RS22755	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
VP_RS22760	ENOG4105ETT	transcriptional Regulator, LysR family
VP_RS22770	ENOG4108RCM	Nitroreductase
VP_RS22775	ENOG4108ZX5	transcriptional regulator
VP_RS22785	ENOG4105DZ1	carboxypeptidase
VP_RS22800	ENOG4105C72	UPF0176 protein
VP_RS22805	ENOG4108M1A	Chitin-binding protein
VP_RS22810	ENOG4108NRW	Phospholipase, patatin family
VP_RS22815	ENOG41081FY	multiple antibiotic resistance (MarC)-related
VP_RS22825	ENOG4105DAY	polysaccharide export protein
VP_RS22835	ENOG4105D75	Capsular exopolysaccharide family
VP_RS22845	ENOG4105N0V	mono-oxygenase ydhR
VP_RS22850	ENOG4105F04	LysR family Transcriptional regulator
VP_RS22860	ENOG4105CK2	sodium dicarboxylate symporter
VP_RS22870	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
VP_RS22875	ENOG4108P2H	Inner membrane protein YjiG
VP_RS22880	ENOG41074DU	domain protein
VP_RS22895	ENOG4107T9C	Alpha amylase catalytic region
VP_RS22900	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
VP_RS22905	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
VP_RS22910	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
VP_RS22915	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
VP_RS22920	ENOG41061ZR	Transcriptional regulator
VP_RS22950	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
VP_RS22955	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
VP_RS22965	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
VP_RS22975	ENOG4105D5Q	Arginine ornithine antiporter
VP_RS22980	ENOG4105CXN	decarboxylase
VP_RS23000	ENOG4108K8S	endonuclease I
VP_RS23020	ENOG4108KDD	Involved in the transport of maltose and maltodextrins (By similarity)
VP_RS23045	ENOG4105DR5	peptidase
VP_RS23055	ENOG4107RAN	Peptidase, M16
VP_RS23060	ENOG4105C8Q	Methyl-accepting chemotaxis
VP_RS23065	ENOG4105E0A	ABC, transporter
VP_RS23070	ENOG4108U1V	ABC transporter, permease
VP_RS23075	ENOG4105DQ5	transport system permease protein
VP_RS23080	ENOG4108HUF	Transporter
VP_RS23085	ENOG4105GAV	receptor
VP_RS23090	ENOG4105E0K	tonB-dependent siderophore receptor
VP_RS23100	ENOG4105DUU	IucA IucC family protein
VP_RS23110	ENOG4105DBM	Siderophore biosynthesis protein
VP_RS23115	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
VP_RS23120	ENOG4108JP0	extracellular solute-binding protein family 1
VP_RS23125	ENOG4105DHQ	Histidine kinase
VP_RS23135	ENOG4105CI1	PTS System
VP_RS23150	ENOG4105CNN	ABC, transporter
VP_RS23155	ENOG4105C2J	ABC transporter
VP_RS23160	ENOG4105DMK	Periplasmic binding protein LacI transcriptional regulator
VP_RS23165	ENOG4105EF1	ribulokinase
VP_RS23175	ENOG4105CAC	Catalyzes the conversion of L-arabinose to L-ribulose (By similarity)
VP_RS23200	ENOG4108ZHJ	Organic hydroperoxide resistance protein
VP_RS23205	ENOG4105K56	Transcriptional regulator
VP_RS23210	ENOG4105D3R	alkyl hydroperoxide reductase
VP_RS23215	ENOG4108JU3	Alkyl hydroperoxide reductase
VP_RS23235	ENOG4105ECQ	AraC Family Transcriptional Regulator
VP_RS23240	ENOG4105DU6	RNA polymerase
VP_RS23250	ENOG4105C8Q	Methyl-accepting chemotaxis
VP_RS23255	ENOG4105W8I	Transcriptional regulator
VP_RS23260	ENOG4105F8D	glycoside hydrolase family 4
VP_RS23275	ENOG4108RPX	mosc domain containing protein
VP_RS23280	ENOG4105C1J	atp-dependent rna helicase
VP_RS23285	ENOG4105CHZ	Catalyzes the dehydration of D-mannonate (By similarity)
VP_RS23290	ENOG4105C6F	GntR Family Transcriptional Regulator
VP_RS23295	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
VP_RS23300	ENOG4105XDZ	Tripartite ATP-independent periplasmic transporter
VP_RS23305	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
VP_RS23310	ENOG4105DEI	Mannitol dehydrogenase
VP_RS23315	ENOG4105D2H	Uronic isomerase
VP_RS23320	ENOG4107SS6	2-dehydro-3-deoxygluconokinase
VP_RS23325	ENOG4108UHU	Aldolase
VP_RS23330	ENOG4105P66	Membrane
VP_RS23345	ENOG4105CF7	AraC family transcriptional regulator
VP_RS23355	ENOG4105BZ1	(ABC) transporter
VP_RS23365	ENOG4105EW9	transcriptional regulator AsnC family
VP_RS23395	ENOG4105CK7	Sodium proline symporter
VP_RS23405	ENOG4105C26	Dehydrogenase
VP_RS23420	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
VP_RS23425	ENOG4105CQZ	Histidine kinase
VP_RS23430	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
VP_RS23435	ENOG4107QZV	Type I secretion membrane fusion protein
VP_RS23450	ENOG4108JJA	ABC, transporter
VP_RS23465	ENOG4108J59	Extracellular solute-binding protein, family 5
VP_RS23475	ENOG4108PSC	Represses the expression of the murPQ operon involved in the uptake and degradation of N-acetylmuramic acid (MurNAc). Binds to two adjacent inverted repeats within the operator region. MurNAc 6-phosphate, the substrate of MurQ, is the specific inducer that weakens binding of MurR to the operator (By similarity)
VP_RS23480	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
VP_RS23485	ENOG4105C5Y	PTS System
VP_RS23490	ENOG4105FCK	Membrane
VP_RS23495	ENOG4105EC3	peptidase S51, dipeptidase E
VP_RS23500	ENOG4105EQ2	LysR family Transcriptional regulator
VP_RS23515	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
VP_RS23520	ENOG4106RMF	ParB family