locus-tag	class	description
JHT10_RS00020	COG0641	radical SAM
JHT10_RS00040	COG0840	transmembrane signaling receptor activity
JHT10_RS00045	COG1119	ATPase activity
JHT10_RS00050	COG2200	EAL domain
JHT10_RS00070	COG0513	Belongs to the DEAD box helicase family
JHT10_RS00075	COG0523	cobalamin synthesis protein
JHT10_RS00085	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
JHT10_RS00095	COG0133	tryptophan synthase activity
JHT10_RS00100	COG4628	conserved protein (DUF2132)
JHT10_RS00105	COG0513	Belongs to the DEAD box helicase family
JHT10_RS00110	COG3530	Putative quorum-sensing-regulated virulence factor
JHT10_RS00130	COG2154	pterin-4-alpha-carbinolamine dehydratase
JHT10_RS00135	COG3186	Phenylalanine-4-hydroxylase
JHT10_RS00140	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JHT10_RS00145	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
JHT10_RS00185	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
JHT10_RS00190	COG1454	alcohol dehydrogenase
JHT10_RS00195	COG2133	pyrroloquinoline quinone binding
JHT10_RS00205	COG0783	Belongs to the Dps family
JHT10_RS00210	COG0840	transmembrane signaling receptor activity
JHT10_RS00220	COG1136	(ABC) transporter
JHT10_RS00220	COG0577	efflux transmembrane transporter activity
JHT10_RS00240	COG2199	diguanylate cyclase activity
JHT10_RS00250	COG3036	rescue of stalled ribosome
JHT10_RS00255	COG1278	Cold shock
JHT10_RS00285	COG0545	Peptidyl-prolyl cis-trans isomerase
JHT10_RS00290	COG0109	protoheme IX farnesyltransferase activity
JHT10_RS00295	COG1612	heme a metabolic process
JHT10_RS00320	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
JHT10_RS00330	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
JHT10_RS00335	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JHT10_RS00345	COG1280	lysine exporter protein (LysE YggA)
JHT10_RS00375	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
JHT10_RS00380	COG0697	spore germination
JHT10_RS00395	COG2814	Major facilitator Superfamily
JHT10_RS00400	COG0583	DNA-binding transcription factor activity
JHT10_RS00405	COG5001	Diguanylate cyclase
JHT10_RS00410	COG0739	heme binding
JHT10_RS00430	COG3314	Sporulation integral membrane protein YlbJ
JHT10_RS00445	COG0814	amino acid
JHT10_RS00465	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
JHT10_RS00470	COG1072	(Pantothenic acid kinase))
JHT10_RS00480	COG1063	alcohol dehydrogenase
JHT10_RS00485	COG2213	PTS system mannitol-specific
JHT10_RS00490	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JHT10_RS00505	COG0798	PFAM Bile acid sodium symporter
JHT10_RS00515	COG1881	PFAM PEBP family protein
JHT10_RS00525	COG2706	6-phosphogluconolactonase activity
JHT10_RS00540	COG1131	(ABC) transporter
JHT10_RS00545	COG0842	Transport permease protein
JHT10_RS00560	COG3383	formate dehydrogenase (NAD+) activity
JHT10_RS00580	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JHT10_RS00610	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JHT10_RS00620	COG2067	long-chain fatty acid transport protein
JHT10_RS00630	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JHT10_RS00640	COG1505	serine-type exopeptidase activity
JHT10_RS00645	COG0488	(ABC) transporter
JHT10_RS00650	COG0589	response to stress
JHT10_RS00655	COG2249	NAD(P)H dehydrogenase (quinone) activity
JHT10_RS00675	COG0366	Alpha amylase catalytic
JHT10_RS00685	COG4934	collagen metabolic process
JHT10_RS00700	COG0583	DNA-binding transcription factor activity
JHT10_RS00705	COG0783	Belongs to the Dps family
JHT10_RS00710	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
JHT10_RS00735	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
JHT10_RS00735	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JHT10_RS00745	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JHT10_RS00750	COG0784	Response regulator, receiver
JHT10_RS00750	COG0835	chemotaxis
JHT10_RS00760	COG0748	coenzyme F420 binding
JHT10_RS00765	COG3721	Heme iron utilization protein
JHT10_RS00775	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
JHT10_RS00780	COG0811	peptide transport
JHT10_RS00785	COG0848	biopolymer transport protein
JHT10_RS00795	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JHT10_RS00800	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
JHT10_RS00840	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
JHT10_RS00845	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
JHT10_RS00850	COG3217	Mosc domain protein beta barrel domain protein
JHT10_RS00850	COG3217	Mosc domain protein beta barrel domain protein
JHT10_RS00850	COG0633	Ferredoxin
JHT10_RS00850	COG0633	Ferredoxin
JHT10_RS00855	COG0401	homolog of Blt101
JHT10_RS00860	COG0418	dihydroorotase activity
JHT10_RS00865	COG2354	Protein conserved in bacteria
JHT10_RS00895	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JHT10_RS00895	COG2207	Transcriptional regulator
JHT10_RS00900	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JHT10_RS00940	COG0513	Belongs to the DEAD box helicase family
JHT10_RS00950	COG0583	DNA-binding transcription factor activity
JHT10_RS00965	COG1902	pentaerythritol trinitrate reductase activity
JHT10_RS00970	COG1063	alcohol dehydrogenase
JHT10_RS00980	COG1028	Short-chain dehydrogenase reductase Sdr
JHT10_RS00990	COG3122	Protein conserved in bacteria
JHT10_RS01010	COG0583	DNA-binding transcription factor activity
JHT10_RS01015	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
JHT10_RS01020	COG0252	asparaginase activity
JHT10_RS01025	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
JHT10_RS01030	COG0574	Belongs to the PEP-utilizing enzyme family
JHT10_RS01030	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JHT10_RS01045	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JHT10_RS01065	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JHT10_RS01085	COG3706	GGDEF domain
JHT10_RS01105	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JHT10_RS01135	COG3842	ATPase activity
JHT10_RS01165	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JHT10_RS01200	COG0583	DNA-binding transcription factor activity
JHT10_RS01210	COG4948	Mandelate Racemase Muconate Lactonizing
JHT10_RS01240	COG1342	Belongs to the UPF0251 family
JHT10_RS01245	COG3015	lipoprotein NlpE involved in copper resistance
JHT10_RS01250	COG3713	MltA-interacting MipA family protein
JHT10_RS01265	COG0583	DNA-binding transcription factor activity
JHT10_RS01290	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
JHT10_RS01300	COG1335	isochorismatase
JHT10_RS01310	COG0753	catalase activity
JHT10_RS01320	COG1349	DNA-binding transcription factor activity
JHT10_RS01325	COG0346	lactoylglutathione lyase activity
JHT10_RS01345	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JHT10_RS01350	COG3537	Alpha-1,2-mannosidase
JHT10_RS01355	COG3537	Alpha-1,2-mannosidase
JHT10_RS01365	COG3537	Alpha-1,2-mannosidase
JHT10_RS01370	COG3537	Alpha-1,2-mannosidase
JHT10_RS01380	COG0737	Belongs to the 5'-nucleotidase family
JHT10_RS01390	COG1309	transcriptional regulator
JHT10_RS01410	COG1280	lysine exporter protein (LysE YggA)
JHT10_RS01425	COG0459	protein refolding
JHT10_RS01430	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
JHT10_RS01435	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JHT10_RS01460	COG1304	FMN binding
JHT10_RS01480	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JHT10_RS01485	COG4786	Flagellar basal body rod
JHT10_RS01485	COG1256	bacterial-type flagellum assembly
JHT10_RS01495	COG1706	bacterial-type flagellum-dependent cell motility
JHT10_RS01500	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
JHT10_RS01505	COG4786	Flagellar basal body rod
JHT10_RS01510	COG4787	bacterial-type flagellum-dependent cell motility
JHT10_RS01515	COG1749	Flagellar hook protein flgE
JHT10_RS01520	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
JHT10_RS01525	COG1558	bacterial-type flagellum-dependent cell motility
JHT10_RS01530	COG1815	bacterial-type flagellum-dependent cell motility
JHT10_RS01550	COG0741	lytic transglycosylase activity
JHT10_RS01555	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JHT10_RS01575	COG1760	l-serine dehydratase
JHT10_RS01580	COG3104	oligopeptide transport
JHT10_RS01600	COG0583	DNA-binding transcription factor activity
JHT10_RS01610	COG2866	Carboxypeptidase
JHT10_RS01615	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JHT10_RS01620	COG2990	Protein conserved in bacteria
JHT10_RS01645	COG3842	ATPase activity
JHT10_RS01655	COG1840	ABC-type Fe3 transport system, periplasmic component
JHT10_RS01660	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
JHT10_RS01665	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JHT10_RS01670	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JHT10_RS01675	COG1609	Transcriptional regulator
JHT10_RS01705	COG3240	lipase activity
JHT10_RS01715	COG1136	(ABC) transporter
JHT10_RS01715	COG0577	efflux transmembrane transporter activity
JHT10_RS01720	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JHT10_RS01725	COG2067	long-chain fatty acid transport protein
JHT10_RS01735	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
JHT10_RS01750	COG1011	Hydrolase
JHT10_RS01790	COG0110	maltose O-acetyltransferase activity
JHT10_RS01795	COG1765	OsmC-like protein
JHT10_RS01830	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JHT10_RS01830	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JHT10_RS01845	COG3046	protein related to deoxyribodipyrimidine photolyase
JHT10_RS01850	COG0415	Belongs to the DNA photolyase family
JHT10_RS01855	COG3706	GGDEF domain
JHT10_RS01870	COG0840	transmembrane signaling receptor activity
JHT10_RS01875	COG3706	GGDEF domain
JHT10_RS01890	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JHT10_RS01905	COG3033	Beta-eliminating lyase
JHT10_RS01915	COG0579	oxidoreductase
JHT10_RS01930	COG1114	Component of the transport system for branched-chain amino acids
JHT10_RS01935	COG2199	diguanylate cyclase activity
JHT10_RS01975	COG0583	DNA-binding transcription factor activity
JHT10_RS01980	COG0189	ligase activity
JHT10_RS01985	COG0189	ligase activity
JHT10_RS01985	COG4067	protein conserved in archaea
JHT10_RS01995	COG1166	arginine decarboxylase activity
JHT10_RS02000	COG0010	Belongs to the arginase family
JHT10_RS02005	COG2814	Major facilitator Superfamily
JHT10_RS02010	COG1770	oligopeptidase
JHT10_RS02025	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JHT10_RS02030	COG1121	(ABC) transporter
JHT10_RS02035	COG0803	Belongs to the bacterial solute-binding protein 9 family
JHT10_RS02075	COG0848	biopolymer transport protein
JHT10_RS02080	COG0811	peptide transport
JHT10_RS02085	COG0811	peptide transport
JHT10_RS02105	COG0745	RESPONSE REGULATOR receiver
JHT10_RS02110	COG0039	L-malate dehydrogenase activity
JHT10_RS02115	COG0584	glycerophosphoryl diester phosphodiesterase
JHT10_RS02125	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JHT10_RS02180	COG1901	pseudouridine methyltransferase
JHT10_RS02185	COG0312	modulator of DNA gyrase
JHT10_RS02190	COG0312	modulator of DNA gyrase
JHT10_RS02195	COG0351	phosphomethylpyrimidine kinase
JHT10_RS02200	COG1116	anion transmembrane transporter activity
JHT10_RS02205	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JHT10_RS02210	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JHT10_RS02215	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
JHT10_RS02220	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
JHT10_RS02225	COG0352	thiamine-phosphate diphosphorylase activity
JHT10_RS02235	COG0243	molybdopterin cofactor binding
JHT10_RS02240	COG3005	denitrification pathway
JHT10_RS02250	COG1028	Short-chain dehydrogenase reductase Sdr
JHT10_RS02265	COG0456	acetyltransferase
JHT10_RS02285	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JHT10_RS02290	COG1929	Belongs to the glycerate kinase type-1 family
JHT10_RS02295	COG2610	gluconate transmembrane transporter activity
JHT10_RS02300	COG3835	regulator
JHT10_RS02325	COG0546	phosphoglycolate phosphatase activity
JHT10_RS02340	COG0583	DNA-binding transcription factor activity
JHT10_RS02350	COG0583	DNA-binding transcription factor activity
JHT10_RS02360	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
JHT10_RS02365	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
JHT10_RS02365	COG3408	Glycogen debranching enzyme
JHT10_RS02395	COG3047	cAMP biosynthetic process
JHT10_RS02400	COG1357	PFAM Pentapeptide repeats (8 copies)
JHT10_RS02430	COG2375	cellular response to nickel ion
JHT10_RS02435	COG0823	Involved in the tonB-independent uptake of proteins
JHT10_RS02440	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JHT10_RS02460	COG0800	Aldolase
JHT10_RS02465	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JHT10_RS02480	COG1917	Cupin 2, conserved barrel domain protein
JHT10_RS02490	COG1028	Short-chain dehydrogenase reductase Sdr
JHT10_RS02495	COG1414	Transcriptional regulator
JHT10_RS02510	COG0583	DNA-binding transcription factor activity
JHT10_RS02515	COG2162	N-hydroxyarylamine O-acetyltransferase activity
JHT10_RS02520	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
JHT10_RS02535	COG2199	diguanylate cyclase activity
JHT10_RS02545	COG0561	phosphatase activity
JHT10_RS02550	COG0583	DNA-binding transcription factor activity
JHT10_RS02565	COG0564	pseudouridine synthase activity
JHT10_RS02570	COG0534	Mate efflux family protein
JHT10_RS02575	COG5001	Diguanylate cyclase
JHT10_RS02585	COG3123	guanosine phosphorylase activity
JHT10_RS02625	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JHT10_RS02635	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JHT10_RS02640	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
JHT10_RS02650	COG2259	Doxx family
JHT10_RS02655	COG1741	Belongs to the pirin family
JHT10_RS02675	COG0363	glucosamine-6-phosphate deaminase activity
JHT10_RS02685	COG0786	glutamate:sodium symporter activity
JHT10_RS02690	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JHT10_RS02695	COG1131	(ABC) transporter
JHT10_RS02705	COG0786	glutamate:sodium symporter activity
JHT10_RS02730	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JHT10_RS02740	COG3279	Response regulator of the LytR AlgR family
JHT10_RS02745	COG3275	phosphorelay sensor kinase activity
JHT10_RS02775	COG0772	Belongs to the SEDS family
JHT10_RS02780	COG0217	transcriptional regulatory protein
JHT10_RS02800	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JHT10_RS02800	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
JHT10_RS02810	COG0444	Belongs to the ABC transporter superfamily
JHT10_RS02815	COG4608	Belongs to the ABC transporter superfamily
JHT10_RS02840	COG1444	tRNA N-acetyltransferase activity
JHT10_RS02860	COG3340	Belongs to the peptidase S51 family
JHT10_RS02865	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
JHT10_RS02870	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JHT10_RS02870	COG1263	PTS System
JHT10_RS02875	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
JHT10_RS02935	COG0259	pyridoxamine-phosphate oxidase activity
JHT10_RS02960	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JHT10_RS03005	COG1132	(ABC) transporter
JHT10_RS03015	COG2207	Transcriptional regulator
JHT10_RS03030	COG0513	Belongs to the DEAD box helicase family
JHT10_RS03035	COG2258	MOSC domain
JHT10_RS03050	COG1486	melibiose metabolic process
JHT10_RS03055	COG0583	DNA-binding transcription factor activity
JHT10_RS03070	COG1595	DNA-templated transcription, initiation
JHT10_RS03095	COG3634	alkyl hydroperoxide reductase activity
JHT10_RS03105	COG1846	Transcriptional regulator
JHT10_RS03110	COG1764	response to oxidative stress
JHT10_RS03135	COG2160	L-arabinose isomerase activity
JHT10_RS03145	COG1069	ribulokinase activity
JHT10_RS03150	COG1879	ABC-type sugar transport system periplasmic component
JHT10_RS03155	COG1129	ABC transporter
JHT10_RS03160	COG1172	Belongs to the binding-protein-dependent transport system permease family
JHT10_RS03165	COG0826	peptidase U32
JHT10_RS03190	COG1653	transport
JHT10_RS03195	COG0019	diaminopimelate decarboxylase activity
JHT10_RS03200	COG4264	IucA IucC family
JHT10_RS03225	COG4772	TonB-dependent receptor
JHT10_RS03230	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
JHT10_RS03235	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JHT10_RS03240	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JHT10_RS03245	COG1120	ATPase activity
JHT10_RS03250	COG0840	transmembrane signaling receptor activity
JHT10_RS03255	COG0612	Peptidase, M16
JHT10_RS03265	COG0739	heme binding
JHT10_RS03275	COG2814	Major facilitator Superfamily
JHT10_RS03290	COG4580	involved in the transport of maltose and maltodextrins
JHT10_RS03310	COG2356	endonuclease I
JHT10_RS03330	COG1982	Orn Lys Arg decarboxylase major
JHT10_RS03335	COG0531	amino acid
JHT10_RS03345	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
JHT10_RS03355	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
JHT10_RS03360	COG1162	GTPase activity
JHT10_RS03365	COG1263	PTS System
JHT10_RS03365	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JHT10_RS03375	COG1999	signal sequence binding
JHT10_RS03390	COG2909	trisaccharide binding
JHT10_RS03395	COG0058	SHG alpha-glucan phosphorylase activity
JHT10_RS03400	COG1640	4-alpha-glucanotransferase
JHT10_RS03405	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
JHT10_RS03410	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JHT10_RS03415	COG0366	Alpha amylase catalytic
JHT10_RS03425	COG3366	ferrous iron transmembrane transporter activity
JHT10_RS03430	COG0700	Nucleoside recognition
JHT10_RS03435	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JHT10_RS03440	COG3339	Conserved Protein
JHT10_RS03445	COG1301	dicarboxylic acid transport
JHT10_RS03455	COG0583	DNA-binding transcription factor activity
JHT10_RS03470	COG0489	protein tyrosine kinase activity
JHT10_RS03470	COG3206	protein involved in exopolysaccharide biosynthesis
JHT10_RS03490	COG2095	MarC family integral membrane protein
JHT10_RS03495	COG4667	esterase of the alpha-beta hydrolase superfamily
JHT10_RS03500	COG3397	chitin binding
JHT10_RS03505	COG1054	Belongs to the UPF0176 family
JHT10_RS03520	COG1686	Belongs to the peptidase S11 family
JHT10_RS03545	COG0583	DNA-binding transcription factor activity
JHT10_RS03550	COG4628	conserved protein (DUF2132)
JHT10_RS03560	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JHT10_RS03570	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
JHT10_RS03575	COG0628	permease
JHT10_RS03615	COG2814	Major facilitator Superfamily
JHT10_RS03625	COG0454	-acetyltransferase
JHT10_RS03635	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
JHT10_RS03640	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
JHT10_RS03645	COG1882	Formate acetyltransferase
JHT10_RS03675	COG1360	Flagellar Motor Protein
JHT10_RS03680	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
JHT10_RS03685	COG1191	sigma factor activity
JHT10_RS03690	COG1580	Controls the rotational direction of flagella during chemotaxis
JHT10_RS03705	COG1516	flagellar protein fliS
JHT10_RS03710	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
JHT10_RS03720	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JHT10_RS03735	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
JHT10_RS03745	COG1987	bacterial-type flagellum assembly
JHT10_RS03825	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
JHT10_RS03845	COG0346	lactoylglutathione lyase activity
JHT10_RS03870	COG0745	RESPONSE REGULATOR receiver
JHT10_RS03890	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JHT10_RS03900	COG0156	8-amino-7-oxononanoate synthase activity
JHT10_RS03905	COG1063	alcohol dehydrogenase
JHT10_RS03940	COG0668	transmembrane transport
JHT10_RS03950	COG1304	FMN binding
JHT10_RS03955	COG1620	l-lactate permease
JHT10_RS03960	COG0583	DNA-binding transcription factor activity
JHT10_RS03965	COG1505	serine-type exopeptidase activity
JHT10_RS03970	COG4172	Belongs to the ABC transporter superfamily
JHT10_RS03980	COG1067	ATP-dependent peptidase activity
JHT10_RS04005	COG1247	-acetyltransferase
JHT10_RS04010	COG0437	4 iron, 4 sulfur cluster binding
JHT10_RS04015	COG0348	domain, Protein
JHT10_RS04030	COG1122	ATPase activity
JHT10_RS04035	COG4720	Psort location CytoplasmicMembrane, score
JHT10_RS04040	COG1566	PFAM secretion protein HlyD family protein
JHT10_RS04050	COG3706	GGDEF domain
JHT10_RS04065	COG0813	purine-nucleoside phosphorylase activity
JHT10_RS04070	COG3272	Protein of unknown function (DUF1722)
JHT10_RS04075	COG0789	Transcriptional regulator
JHT10_RS04080	COG0415	Belongs to the DNA photolyase family
JHT10_RS04085	COG1376	ErfK ybiS ycfS ynhG family protein
JHT10_RS04085	COG1388	LysM domain
JHT10_RS04095	COG0513	Belongs to the DEAD box helicase family
JHT10_RS04100	COG1770	oligopeptidase
JHT10_RS04105	COG4771	TonB-dependent receptor
JHT10_RS04135	COG0573	inorganic phosphate transmembrane transporter activity
JHT10_RS04140	COG0581	inorganic phosphate transmembrane transporter activity
JHT10_RS04145	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JHT10_RS04160	COG2304	oxidoreductase activity
JHT10_RS04180	COG0714	Associated with various cellular activities
JHT10_RS04185	COG0840	transmembrane signaling receptor activity
JHT10_RS04195	COG2197	response regulator
JHT10_RS04245	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
JHT10_RS04250	COG1120	ATPase activity
JHT10_RS04255	COG4774	siderophore transport
JHT10_RS04260	COG1132	(ABC) transporter
JHT10_RS04265	COG2205	protein histidine kinase activity
JHT10_RS04275	COG0569	domain protein
JHT10_RS04280	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JHT10_RS04290	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
JHT10_RS04295	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JHT10_RS04310	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JHT10_RS04310	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JHT10_RS04310	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JHT10_RS04315	COG2207	Transcriptional regulator
JHT10_RS04325	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JHT10_RS04330	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JHT10_RS04335	COG2084	Dehydrogenase
JHT10_RS04340	COG0753	catalase activity
JHT10_RS04350	COG2130	NADP-dependent
JHT10_RS04355	COG1309	transcriptional regulator
JHT10_RS04360	COG3097	Belongs to the UPF0267 family
JHT10_RS04415	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
JHT10_RS04420	COG3842	ATPase activity
JHT10_RS04430	COG1175	transmembrane transport
JHT10_RS04435	COG3833	ABC-type maltose transport systems, permease component
JHT10_RS04460	COG2199	diguanylate cyclase activity
JHT10_RS04460	COG2200	EAL domain
JHT10_RS04460	COG2202	Pas domain
JHT10_RS04565	COG4789	Type iii secretion
JHT10_RS04570	COG4792	protein secretion
JHT10_RS04600	COG3710	Transcriptional regulator
JHT10_RS04610	COG4790	Type iii secretion
JHT10_RS04700	COG2916	Histone family protein nucleoid-structuring protein H-NS
JHT10_RS04720	COG2207	Transcriptional regulator
JHT10_RS04735	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JHT10_RS04745	COG0747	negative chemotaxis
JHT10_RS04765	COG0804	urea catabolic process
JHT10_RS04870	COG3246	L-lysine catabolic process to acetate
JHT10_RS04880	COG3746	phosphate-selective porin O and P
JHT10_RS04895	COG1028	Short-chain dehydrogenase reductase Sdr
JHT10_RS04920	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JHT10_RS04925	COG0494	nUDIX hydrolase
JHT10_RS04930	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JHT10_RS04940	COG0625	glutathione transferase activity
JHT10_RS04945	COG1686	Belongs to the peptidase S11 family
JHT10_RS04960	COG0678	peroxiredoxin activity
JHT10_RS04960	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
JHT10_RS04965	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
JHT10_RS04980	COG1278	Cold shock
JHT10_RS04990	COG4667	esterase of the alpha-beta hydrolase superfamily
JHT10_RS05000	COG1846	Transcriptional regulator
JHT10_RS05015	COG2814	Major facilitator Superfamily
JHT10_RS05025	COG0673	inositol 2-dehydrogenase activity
JHT10_RS05030	COG2194	sulfuric ester hydrolase activity
JHT10_RS05035	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
JHT10_RS05045	COG2205	protein histidine kinase activity
JHT10_RS05050	COG0745	RESPONSE REGULATOR receiver
JHT10_RS05055	COG4221	oxidoreductase activity
JHT10_RS05070	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JHT10_RS05090	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JHT10_RS05100	COG2814	Major facilitator Superfamily
JHT10_RS05110	COG1418	mRNA catabolic process
JHT10_RS05120	COG0402	S-adenosylhomocysteine deaminase activity
JHT10_RS05125	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
JHT10_RS05130	COG2239	Acts as a magnesium transporter
JHT10_RS05135	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
JHT10_RS05150	COG0531	amino acid
JHT10_RS05155	COG1522	sequence-specific DNA binding
JHT10_RS05180	COG0784	Response regulator, receiver
JHT10_RS05180	COG2205	protein histidine kinase activity
JHT10_RS05180	COG5002	protein histidine kinase activity
JHT10_RS05185	COG0673	inositol 2-dehydrogenase activity
JHT10_RS05190	COG0534	Mate efflux family protein
JHT10_RS05195	COG2926	Belongs to the UPF0265 family
JHT10_RS05205	COG3132	Protein of unknown function, DUF480
JHT10_RS05210	COG2827	Endonuclease containing a URI domain
JHT10_RS05215	COG1879	ABC-type sugar transport system periplasmic component
JHT10_RS05220	COG0784	Response regulator, receiver
JHT10_RS05220	COG2205	protein histidine kinase activity
JHT10_RS05230	COG1566	PFAM secretion protein HlyD family protein
JHT10_RS05250	COG1522	sequence-specific DNA binding
JHT10_RS05275	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JHT10_RS05280	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JHT10_RS05300	COG0183	Belongs to the thiolase family
JHT10_RS05320	COG3005	denitrification pathway
JHT10_RS05330	COG0243	molybdopterin cofactor binding
JHT10_RS05340	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
JHT10_RS05345	COG3850	Histidine kinase
JHT10_RS05350	COG2197	response regulator
JHT10_RS05365	COG2195	Cleaves the N-terminal amino acid of tripeptides
JHT10_RS05385	COG0840	transmembrane signaling receptor activity
JHT10_RS05395	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JHT10_RS05405	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
JHT10_RS05410	COG2814	Major facilitator Superfamily
JHT10_RS05415	COG0840	transmembrane signaling receptor activity
JHT10_RS05420	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
JHT10_RS05425	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
JHT10_RS05445	COG2897	thiosulfate sulfurtransferase activity
JHT10_RS05465	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JHT10_RS05475	COG0302	gtp cyclohydrolase
JHT10_RS05480	COG1914	H( )-stimulated, divalent metal cation uptake system
JHT10_RS05490	COG0038	chloride channel
JHT10_RS05505	COG4989	oxidoreductase activity
JHT10_RS05520	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
JHT10_RS05520	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
JHT10_RS05525	COG0516	GMP reductase activity
JHT10_RS05530	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JHT10_RS05595	COG3474	cytochrome
JHT10_RS05605	COG0789	Transcriptional regulator
JHT10_RS05610	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JHT10_RS05615	COG0384	phenazine biosynthesis protein PhzF
JHT10_RS05625	COG1294	oxidase, subunit
JHT10_RS05630	COG1271	oxidase subunit
JHT10_RS05635	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JHT10_RS05640	COG0110	maltose O-acetyltransferase activity
JHT10_RS05645	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
JHT10_RS05645	COG3264	Mechanosensitive ion channel
JHT10_RS05660	COG3437	response regulator, receiver
JHT10_RS05660	COG4999	Histidine kinase
JHT10_RS05660	COG3850	Histidine kinase
JHT10_RS05660	COG2205	protein histidine kinase activity
JHT10_RS05670	COG4770	biotin carboxylase activity
JHT10_RS05680	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JHT10_RS05685	COG1960	acyl-CoA dehydrogenase activity
JHT10_RS05695	COG0183	Belongs to the thiolase family
JHT10_RS05705	COG1960	acyl-CoA dehydrogenase activity
JHT10_RS05710	COG1024	Enoyl-CoA hydratase
JHT10_RS05730	COG3706	GGDEF domain
JHT10_RS05735	COG1309	transcriptional regulator
JHT10_RS05740	COG1012	belongs to the aldehyde dehydrogenase family
JHT10_RS05755	COG4176	ABC-type proline glycine betaine transport system permease component
JHT10_RS05760	COG0517	IMP dehydrogenase activity
JHT10_RS05760	COG4175	Glycine betaine
JHT10_RS05775	COG0330	HflC and HflK could
JHT10_RS05785	COG3300	MHYT domain
JHT10_RS05785	COG5001	Diguanylate cyclase
JHT10_RS05795	COG2205	protein histidine kinase activity
JHT10_RS05795	COG0784	Response regulator, receiver
JHT10_RS05850	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
JHT10_RS05855	COG5001	Diguanylate cyclase
JHT10_RS05860	COG1869	D-ribose catabolic process
JHT10_RS05865	COG1129	ABC transporter
JHT10_RS05870	COG1172	Belongs to the binding-protein-dependent transport system permease family
JHT10_RS05875	COG1879	ABC-type sugar transport system periplasmic component
JHT10_RS05880	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JHT10_RS05885	COG1609	Transcriptional regulator
JHT10_RS05900	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
JHT10_RS05915	COG0745	RESPONSE REGULATOR receiver
JHT10_RS05930	COG1785	Belongs to the alkaline phosphatase family
JHT10_RS05955	COG0814	amino acid
JHT10_RS05965	COG0243	molybdopterin cofactor binding
JHT10_RS05985	COG3707	response regulator
JHT10_RS05990	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JHT10_RS05995	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JHT10_RS06000	COG1116	anion transmembrane transporter activity
JHT10_RS06005	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JHT10_RS06005	COG2146	nitrite reductase [NAD(P)H] activity
JHT10_RS06060	COG0515	serine threonine protein kinase
JHT10_RS06060	COG2815	serine threonine protein kinase
JHT10_RS06095	COG0631	protein serine/threonine phosphatase activity
JHT10_RS06165	COG0420	3'-5' exonuclease activity
JHT10_RS06170	COG0419	ATPase involved in DNA repair
JHT10_RS06190	COG3040	lipid binding
JHT10_RS06200	COG2814	Major facilitator Superfamily
JHT10_RS06210	COG1288	antiporter activity
JHT10_RS06220	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
JHT10_RS06235	COG2425	protein containing a von Willebrand factor type A (vWA) domain
JHT10_RS06250	COG0583	DNA-binding transcription factor activity
JHT10_RS06255	COG0277	FAD linked oxidase domain protein
JHT10_RS06270	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JHT10_RS06310	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
JHT10_RS06310	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JHT10_RS06345	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JHT10_RS06350	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JHT10_RS06360	COG2116	formate transmembrane transporter activity
JHT10_RS06380	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
JHT10_RS06410	COG0534	Mate efflux family protein
JHT10_RS06415	COG3292	Two component regulator propeller
JHT10_RS06415	COG2205	protein histidine kinase activity
JHT10_RS06415	COG0745	RESPONSE REGULATOR receiver
JHT10_RS06425	COG3118	belongs to the thioredoxin family
JHT10_RS06430	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JHT10_RS06455	COG2271	Major facilitator Superfamily
JHT10_RS06460	COG3851	Histidine kinase
JHT10_RS06465	COG2197	response regulator
JHT10_RS06475	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
JHT10_RS06480	COG0583	DNA-binding transcription factor activity
JHT10_RS06485	COG0243	molybdopterin cofactor binding
JHT10_RS06515	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JHT10_RS06530	COG1328	CTP reductase activity
JHT10_RS06535	COG0602	queuosine metabolic process
JHT10_RS06540	COG0534	Mate efflux family protein
JHT10_RS06555	COG4067	protein conserved in archaea
JHT10_RS06555	COG0189	ligase activity
JHT10_RS06565	COG3111	PFAM Bacterial OB fold (BOF) protein
JHT10_RS06570	COG1492	cobalamin metabolic process
JHT10_RS06575	COG0725	ABC transporter, periplasmic molybdate-binding protein
JHT10_RS06580	COG4149	molybdate abc transporter
JHT10_RS06585	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
JHT10_RS06595	COG2203	Gaf domain
JHT10_RS06595	COG3706	GGDEF domain
JHT10_RS06595	COG4251	negative regulation of phosphorylation
JHT10_RS06595	COG5001	Diguanylate cyclase
JHT10_RS06620	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
JHT10_RS06625	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
JHT10_RS06650	COG3140	Belongs to the UPF0181 family
JHT10_RS06655	COG0589	response to stress
JHT10_RS06665	COG0583	DNA-binding transcription factor activity
JHT10_RS06680	COG0023	Translation Initiation Factor
JHT10_RS06690	COG1181	Belongs to the D-alanine--D-alanine ligase family
JHT10_RS06700	COG0045	succinate-CoA ligase (ADP-forming) activity
JHT10_RS06700	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JHT10_RS06700	COG1042	CoA-binding domain protein
JHT10_RS06705	COG0583	DNA-binding transcription factor activity
JHT10_RS06710	COG4771	TonB-dependent receptor
JHT10_RS06710	COG1629	transport
JHT10_RS06715	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JHT10_RS06720	COG5001	Diguanylate cyclase
JHT10_RS06720	COG5002	protein histidine kinase activity
JHT10_RS06720	COG3447	MASE1 domain protein
JHT10_RS06725	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
JHT10_RS06730	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
JHT10_RS06735	COG1984	allophanate hydrolase subunit 2
JHT10_RS06745	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
JHT10_RS06750	COG4181	ATPase activity
JHT10_RS06760	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
JHT10_RS06765	COG3300	MHYT domain
JHT10_RS06765	COG5001	Diguanylate cyclase
JHT10_RS06775	COG0484	heat shock protein binding
JHT10_RS06800	COG4533	DNA binding
JHT10_RS06810	COG2050	protein possibly involved in aromatic compounds catabolism
JHT10_RS06825	COG2067	long-chain fatty acid transport protein
JHT10_RS06830	COG2267	carboxylic ester hydrolase activity
JHT10_RS06845	COG0861	Integral membrane protein TerC family
JHT10_RS06850	COG0737	Belongs to the 5'-nucleotidase family
JHT10_RS06855	COG3593	DNA synthesis involved in DNA repair
JHT10_RS06865	COG0583	DNA-binding transcription factor activity
JHT10_RS06870	COG2116	formate transmembrane transporter activity
JHT10_RS06875	COG2353	YceI-like domain
JHT10_RS06880	COG3038	cytochrome b561
JHT10_RS06895	COG4943	cyclic-guanylate-specific phosphodiesterase activity
JHT10_RS06900	COG0513	Belongs to the DEAD box helicase family
JHT10_RS06905	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
JHT10_RS06915	COG0546	phosphoglycolate phosphatase activity
JHT10_RS06920	COG3437	response regulator, receiver
JHT10_RS06920	COG0784	Response regulator, receiver
JHT10_RS06935	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JHT10_RS06940	COG2759	Belongs to the formate--tetrahydrofolate ligase family
JHT10_RS06945	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
JHT10_RS06955	COG2207	Transcriptional regulator
JHT10_RS06960	COG1979	alcohol dehydrogenase
JHT10_RS06985	COG2271	Major facilitator Superfamily
JHT10_RS06990	COG0469	pyruvate kinase activity
JHT10_RS06995	COG1126	abc transporter atp-binding protein
JHT10_RS07000	COG0765	amino acid transport
JHT10_RS07005	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JHT10_RS07010	COG0765	amino acid transport
JHT10_RS07015	COG2203	Gaf domain
JHT10_RS07015	COG2199	diguanylate cyclase activity
JHT10_RS07015	COG2200	EAL domain
JHT10_RS07030	COG1609	Transcriptional regulator
JHT10_RS07035	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
JHT10_RS07035	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
JHT10_RS07040	COG1105	Belongs to the carbohydrate kinase PfkB family
JHT10_RS07045	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
JHT10_RS07045	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JHT10_RS07045	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JHT10_RS07085	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JHT10_RS07090	COG0509	glycine decarboxylation via glycine cleavage system
JHT10_RS07095	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JHT10_RS07095	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JHT10_RS07100	COG0653	protein targeting
JHT10_RS07185	COG3344	reverse transcriptase
JHT10_RS07215	COG4735	regulation of single-species biofilm formation
JHT10_RS07255	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
JHT10_RS07260	COG0583	DNA-binding transcription factor activity
JHT10_RS07265	COG2176	DNA-directed DNA polymerase activity
JHT10_RS07310	COG0242	peptide deformylase activity
JHT10_RS07340	COG2239	Acts as a magnesium transporter
JHT10_RS07360	COG0346	lactoylglutathione lyase activity
JHT10_RS07365	COG1902	pentaerythritol trinitrate reductase activity
JHT10_RS07385	COG5642	Protein of unknown function (DUF2384)
JHT10_RS07390	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
JHT10_RS07405	COG4565	transcriptional regulatory protein
JHT10_RS07410	COG3290	protein histidine kinase activity
JHT10_RS07415	COG0471	metal ion transport
JHT10_RS07445	COG2076	Multidrug Resistance protein
JHT10_RS07460	COG0671	phosphoesterase, PA-phosphatase related
JHT10_RS07470	COG2962	Rard protein
JHT10_RS07485	COG0835	chemotaxis
JHT10_RS07485	COG0784	Response regulator, receiver
JHT10_RS07510	COG2197	response regulator
JHT10_RS07520	COG3706	GGDEF domain
JHT10_RS07525	COG2197	response regulator
JHT10_RS07530	COG3300	MHYT domain
JHT10_RS07530	COG5001	Diguanylate cyclase
JHT10_RS07550	COG0583	DNA-binding transcription factor activity
JHT10_RS07610	COG4964	Belongs to the GSP D family
JHT10_RS07635	COG2207	Transcriptional regulator
JHT10_RS07655	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
JHT10_RS07675	COG1214	PFAM Peptidase M22, glycoprotease
JHT10_RS07675	COG0456	acetyltransferase
JHT10_RS07685	COG3069	C4-dicarboxylate transmembrane transporter activity
JHT10_RS07690	COG1704	LemA family
JHT10_RS07695	COG0501	Belongs to the peptidase M48B family
JHT10_RS07720	COG0641	radical SAM
JHT10_RS07735	COG3111	PFAM Bacterial OB fold (BOF) protein
JHT10_RS07740	COG1597	lipid kinase activity
JHT10_RS07745	COG0583	DNA-binding transcription factor activity
JHT10_RS07750	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JHT10_RS07780	COG0714	Associated with various cellular activities
JHT10_RS07785	COG0641	radical SAM
JHT10_RS07790	COG3119	arylsulfatase activity
JHT10_RS07805	COG3119	arylsulfatase activity
JHT10_RS07810	COG3119	arylsulfatase activity
JHT10_RS07815	COG0745	RESPONSE REGULATOR receiver
JHT10_RS07830	COG2205	protein histidine kinase activity
JHT10_RS07830	COG0784	Response regulator, receiver
JHT10_RS07830	COG2198	Histidine kinase
JHT10_RS07835	COG1879	ABC-type sugar transport system periplasmic component
JHT10_RS07840	COG1803	Methylglyoxal synthase
JHT10_RS07845	COG0210	DNA helicase
JHT10_RS07850	COG1289	transmembrane transporter activity
JHT10_RS07880	COG1629	transport
JHT10_RS07880	COG4771	TonB-dependent receptor
JHT10_RS07885	COG2207	Transcriptional regulator
JHT10_RS07890	COG0789	Transcriptional regulator
JHT10_RS07895	COG4604	ABC transporter, ATP-binding protein
JHT10_RS07900	COG4605	iron ion homeostasis
JHT10_RS07905	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JHT10_RS07910	COG4607	ABC-type enterochelin transport system periplasmic component
JHT10_RS07930	COG2847	Copper chaperone PCu(A)C
JHT10_RS07935	COG0443	Heat shock 70 kDa protein
JHT10_RS07970	COG0625	glutathione transferase activity
JHT10_RS07985	COG4160	amino acid transport
JHT10_RS07990	COG4215	(ABC) transporter
JHT10_RS07995	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JHT10_RS08000	COG1126	abc transporter atp-binding protein
JHT10_RS08010	COG1902	pentaerythritol trinitrate reductase activity
JHT10_RS08015	COG0109	protoheme IX farnesyltransferase activity
JHT10_RS08020	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
JHT10_RS08025	COG1845	cytochrome c oxidase, subunit III
JHT10_RS08030	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JHT10_RS08035	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
JHT10_RS08040	COG1028	Short-chain dehydrogenase reductase Sdr
JHT10_RS08050	COG1024	Enoyl-CoA hydratase
JHT10_RS08055	COG1024	Enoyl-CoA hydratase
JHT10_RS08070	COG0183	Belongs to the thiolase family
JHT10_RS08080	COG1960	acyl-CoA dehydrogenase activity
JHT10_RS08085	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JHT10_RS08090	COG1024	Enoyl-CoA hydratase
JHT10_RS08100	COG5413	integral membrane protein
JHT10_RS08115	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JHT10_RS08120	COG5001	Diguanylate cyclase
JHT10_RS08125	COG0513	Belongs to the DEAD box helicase family
JHT10_RS08130	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
JHT10_RS08145	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
JHT10_RS08150	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JHT10_RS08155	COG0592	DNA-directed DNA polymerase activity
JHT10_RS08160	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JHT10_RS08165	COG0187	DNA topoisomerase II activity
JHT10_RS08175	COG0071	Belongs to the small heat shock protein (HSP20) family
JHT10_RS08180	COG3977	Valine--pyruvate aminotransferase
JHT10_RS08190	COG0751	glycine-tRNA ligase activity
JHT10_RS08195	COG0752	glycyl-tRNA synthetase alpha subunit
JHT10_RS08200	COG2119	membrane
JHT10_RS08210	COG0425	Belongs to the sulfur carrier protein TusA family
JHT10_RS08225	COG0604	alcohol dehydrogenase
JHT10_RS08230	COG0183	Belongs to the thiolase family
JHT10_RS08235	COG1024	Enoyl-CoA hydratase
JHT10_RS08235	COG1250	3-hydroxyacyl-CoA dehydrogenase
JHT10_RS08240	COG1739	Uncharacterized protein family UPF0029
JHT10_RS08245	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JHT10_RS08280	COG0583	DNA-binding transcription factor activity
JHT10_RS08285	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
JHT10_RS08290	COG2960	long-chain fatty acid transporting porin activity
JHT10_RS08295	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JHT10_RS08300	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JHT10_RS08350	COG4172	Belongs to the ABC transporter superfamily
JHT10_RS08355	COG0747	negative chemotaxis
JHT10_RS08360	COG0601	transmembrane transport
JHT10_RS08365	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JHT10_RS08400	COG1609	Transcriptional regulator
JHT10_RS08405	COG0583	DNA-binding transcription factor activity
JHT10_RS08420	COG0129	dihydroxy-acid dehydratase activity
JHT10_RS08425	COG3265	gluconokinase activity
JHT10_RS08430	COG2610	gluconate transmembrane transporter activity
JHT10_RS08435	COG0800	Aldolase
JHT10_RS08440	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
JHT10_RS08445	COG0583	DNA-binding transcription factor activity
JHT10_RS08450	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JHT10_RS08455	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
JHT10_RS08460	COG0339	signal peptide processing
JHT10_RS08465	COG1522	sequence-specific DNA binding
JHT10_RS08470	COG5002	protein histidine kinase activity
JHT10_RS08470	COG5001	Diguanylate cyclase
JHT10_RS08475	COG0742	ribosomal rna small subunit methyltransferase
JHT10_RS08490	COG0589	response to stress
JHT10_RS08495	COG1528	Iron-storage protein
JHT10_RS08505	COG2081	HI0933 family
JHT10_RS08565	COG0628	permease
JHT10_RS08580	COG1322	Protein conserved in bacteria
JHT10_RS08585	COG2226	methyltransferase
JHT10_RS08590	COG3165	ubiquinone biosynthetic process from chorismate
JHT10_RS08595	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
JHT10_RS08600	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JHT10_RS08605	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JHT10_RS08610	COG0805	protein transport
JHT10_RS08615	COG0084	hydrolase, TatD family'
JHT10_RS08630	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JHT10_RS08630	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JHT10_RS08635	COG0218	Necessary for normal cell division and for the maintenance of normal septation
JHT10_RS08665	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
JHT10_RS08675	COG2204	response regulator
JHT10_RS08680	COG3852	Histidine kinase
JHT10_RS08690	COG0174	glutamine synthetase
JHT10_RS08695	COG1217	gtp-binding protein TYPA
JHT10_RS08710	COG1295	ribonuclease BN
JHT10_RS08715	COG1490	D-aminoacyl-tRNA deacylase activity
JHT10_RS08720	COG0456	acetyltransferase
JHT10_RS08730	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
JHT10_RS08735	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
JHT10_RS08740	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
JHT10_RS08745	COG3031	protein transport across the cell outer membrane
JHT10_RS08755	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JHT10_RS08760	COG1459	type II secretion system
JHT10_RS08765	COG2165	general secretion pathway protein
JHT10_RS08770	COG2165	general secretion pathway protein
JHT10_RS08775	COG2165	general secretion pathway protein
JHT10_RS08780	COG4795	General secretion pathway protein
JHT10_RS08785	COG3156	type II secretion system protein K
JHT10_RS08790	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
JHT10_RS08795	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
JHT10_RS08805	COG1218	3'(2'),5'-bisphosphate nucleotidase
JHT10_RS08810	COG0494	nUDIX hydrolase
JHT10_RS08815	COG0316	Belongs to the HesB IscA family
JHT10_RS08815	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
JHT10_RS08820	COG1040	competence protein
JHT10_RS08825	COG0596	Alpha beta hydrolase
JHT10_RS08835	COG2183	response to ionizing radiation
JHT10_RS08845	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JHT10_RS08865	COG2233	PERMEase
JHT10_RS08870	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JHT10_RS08875	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JHT10_RS08880	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JHT10_RS08885	COG1758	RNA polymerase activity
JHT10_RS08890	COG0194	GDP metabolic process
JHT10_RS08905	COG0848	biopolymer transport protein
JHT10_RS08910	COG0811	peptide transport
JHT10_RS08930	COG4174	ABC transporter (Permease)
JHT10_RS08935	COG4239	(ABC) transporter, permease
JHT10_RS08940	COG0747	negative chemotaxis
JHT10_RS08945	COG0444	Belongs to the ABC transporter superfamily
JHT10_RS08950	COG4608	Belongs to the ABC transporter superfamily
JHT10_RS08960	COG5001	Diguanylate cyclase
JHT10_RS09010	COG2246	polysaccharide biosynthetic process
JHT10_RS09025	COG1561	YicC-like family, N-terminal region
JHT10_RS09030	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
JHT10_RS09035	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
JHT10_RS09040	COG1560	Kdo2-lipid A biosynthetic process
JHT10_RS09045	COG1309	transcriptional regulator
JHT10_RS09050	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JHT10_RS09060	COG2003	Belongs to the UPF0758 family
JHT10_RS09065	COG0227	Belongs to the bacterial ribosomal protein bL28 family
JHT10_RS09080	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
JHT10_RS09085	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
JHT10_RS09100	COG0463	Glycosyl transferase, family 2
JHT10_RS09105	COG0859	PFAM glycosyl transferase family 9
JHT10_RS09110	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
JHT10_RS09115	COG3642	lipopolysaccharide core region biosynthetic process
JHT10_RS09135	COG0110	maltose O-acetyltransferase activity
JHT10_RS09140	COG2030	dehydratase
JHT10_RS09160	COG0297	glycogen (starch) synthase activity
JHT10_RS09160	COG0438	transferase activity, transferring glycosyl groups
JHT10_RS09170	COG1519	Transferase
JHT10_RS09175	COG0859	PFAM glycosyl transferase family 9
JHT10_RS09180	COG1560	Kdo2-lipid A biosynthetic process
JHT10_RS09190	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JHT10_RS09225	COG1086	Polysaccharide biosynthesis protein
JHT10_RS09230	COG1083	cytidylyl-transferase
JHT10_RS09240	COG2089	acid synthase
JHT10_RS09295	COG1482	cell wall glycoprotein biosynthetic process
JHT10_RS09310	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
JHT10_RS09325	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
JHT10_RS09330	COG0149	triose-phosphate isomerase activity
JHT10_RS09355	COG1494	fructose-1,6-bisphosphatase
JHT10_RS09360	COG3074	FtsZ-dependent cytokinesis
JHT10_RS09365	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
JHT10_RS09370	COG1575	Belongs to the MenA family. Type 1 subfamily
JHT10_RS09375	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
JHT10_RS09380	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
JHT10_RS09390	COG1609	Transcriptional regulator
JHT10_RS09395	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JHT10_RS09400	COG0254	rRNA binding
JHT10_RS09410	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
JHT10_RS09415	COG0088	Forms part of the polypeptide exit tunnel
JHT10_RS09425	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
JHT10_RS09430	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
JHT10_RS09435	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
JHT10_RS09440	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
JHT10_RS09450	COG0255	Belongs to the universal ribosomal protein uL29 family
JHT10_RS09455	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
JHT10_RS09460	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
JHT10_RS09465	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
JHT10_RS09470	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
JHT10_RS09475	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JHT10_RS09480	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
JHT10_RS09485	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
JHT10_RS09500	COG1841	ribosomal large subunit assembly
JHT10_RS09505	COG0200	Binds to the 23S rRNA
JHT10_RS09510	COG0201	protein transport
JHT10_RS09515	COG0257	Belongs to the bacterial ribosomal protein bL36 family
JHT10_RS09520	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
JHT10_RS09525	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
JHT10_RS09535	COG0202	RNA polymerase activity
JHT10_RS09540	COG0203	ribosomal protein L17
JHT10_RS09550	COG0545	Peptidyl-prolyl cis-trans isomerase
JHT10_RS09560	COG2153	protein acetylation
JHT10_RS09565	COG0513	Belongs to the DEAD box helicase family
JHT10_RS09575	COG0737	Belongs to the 5'-nucleotidase family
JHT10_RS09580	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
JHT10_RS09580	COG1648	precorrin-2 dehydrogenase activity
JHT10_RS09585	COG0175	sulfate reduction
JHT10_RS09590	COG2895	sulfate adenylyltransferase (ATP) activity
JHT10_RS09595	COG0471	metal ion transport
JHT10_RS09595	COG3273	potassium ion transport
JHT10_RS09600	COG0529	Catalyzes the synthesis of activated sulfate
JHT10_RS09620	COG1136	(ABC) transporter
JHT10_RS09635	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
JHT10_RS09645	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JHT10_RS09650	COG0729	surface antigen
JHT10_RS09655	COG2911	Protein conserved in bacteria
JHT10_RS09660	COG2105	PFAM AIG2 family protein
JHT10_RS09670	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
JHT10_RS09675	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
JHT10_RS09680	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
JHT10_RS09685	COG0163	prenyltransferase activity
JHT10_RS09690	COG4143	(ABC) transporter
JHT10_RS09695	COG1178	ABC-type Fe3 transport system permease component
JHT10_RS09700	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
JHT10_RS09715	COG2358	TRAP transporter, solute receptor (TAXI family
JHT10_RS09725	COG0039	L-malate dehydrogenase activity
JHT10_RS09735	COG0142	geranyltranstransferase activity
JHT10_RS09740	COG0261	This protein binds to 23S rRNA in the presence of protein L20
JHT10_RS09750	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
JHT10_RS09755	COG2966	Psort location CytoplasmicMembrane, score
JHT10_RS09770	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
JHT10_RS09775	COG2967	ApaG domain
JHT10_RS09780	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
JHT10_RS09785	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
JHT10_RS09790	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JHT10_RS09795	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
JHT10_RS09800	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
JHT10_RS09810	COG0066	3-isopropylmalate dehydratase activity
JHT10_RS09815	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
JHT10_RS09820	COG0473	3-isopropylmalate dehydrogenase activity
JHT10_RS09825	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JHT10_RS09845	COG0583	DNA-binding transcription factor activity
JHT10_RS09850	COG1022	Amp-dependent synthetase and ligase
JHT10_RS09855	COG0028	Belongs to the TPP enzyme family
JHT10_RS09860	COG0440	acetolactate synthase activity
JHT10_RS09875	COG0469	pyruvate kinase activity
JHT10_RS09880	COG1349	DNA-binding transcription factor activity
JHT10_RS09885	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
JHT10_RS09900	COG5002	protein histidine kinase activity
JHT10_RS09905	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JHT10_RS09910	COG3722	fumarate hydratase activity
JHT10_RS09915	COG0246	Mannitol dehydrogenase
JHT10_RS09920	COG2213	PTS system mannitol-specific
JHT10_RS09920	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
JHT10_RS09950	COG1464	Belongs to the NlpA lipoprotein family
JHT10_RS09965	COG0358	DNA primase activity
JHT10_RS09970	COG1610	YqeY-like protein
JHT10_RS09975	COG0828	Belongs to the bacterial ribosomal protein bS21 family
JHT10_RS09980	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
JHT10_RS09985	COG0596	Alpha beta hydrolase
JHT10_RS09990	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
JHT10_RS09995	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
JHT10_RS10000	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
JHT10_RS10005	COG1968	undecaprenyl-diphosphatase activity
JHT10_RS10010	COG0617	tRNA 3'-terminal CCA addition
JHT10_RS10015	COG3267	Type II secretory pathway component ExeA
JHT10_RS10015	COG3409	Peptidoglycan-binding domain 1 protein
JHT10_RS10025	COG4991	sh3 domain protein
JHT10_RS10030	COG0306	phosphate transporter
JHT10_RS10035	COG1392	Phosphate transport regulator
JHT10_RS10040	COG3025	triphosphatase activity
JHT10_RS10055	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
JHT10_RS10060	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
JHT10_RS10060	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
JHT10_RS10065	COG1538	Outer membrane efflux protein
JHT10_RS10070	COG0494	nUDIX hydrolase
JHT10_RS10075	COG3151	Protein conserved in bacteria
JHT10_RS10085	COG3150	esterase
JHT10_RS10095	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JHT10_RS10100	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JHT10_RS10110	COG3105	Protein conserved in bacteria
JHT10_RS10115	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
JHT10_RS10120	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
JHT10_RS10125	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
JHT10_RS10130	COG0723	plastoquinol--plastocyanin reductase activity
JHT10_RS10135	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
JHT10_RS10140	COG2857	Cytochrome c1
JHT10_RS10145	COG0625	glutathione transferase activity
JHT10_RS10150	COG2969	positive regulation of protein catabolic process
JHT10_RS10155	COG2823	Periplasmic or secreted lipoprotein
JHT10_RS10160	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
JHT10_RS10165	COG0792	nuclease activity
JHT10_RS10175	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
JHT10_RS10185	COG0275	rRNA processing
JHT10_RS10190	COG3116	cell division
JHT10_RS10195	COG0768	penicillin binding
JHT10_RS10200	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JHT10_RS10205	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
JHT10_RS10210	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JHT10_RS10215	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JHT10_RS10220	COG0772	Belongs to the SEDS family
JHT10_RS10225	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JHT10_RS10230	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
JHT10_RS10235	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
JHT10_RS10240	COG0849	cell division
JHT10_RS10245	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
JHT10_RS10250	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
JHT10_RS10260	COG0653	protein targeting
JHT10_RS10265	COG0494	nUDIX hydrolase
JHT10_RS10270	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
JHT10_RS10275	COG0505	Belongs to the CarA family
JHT10_RS10280	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
JHT10_RS10290	COG0730	response to heat
JHT10_RS10295	COG0583	DNA-binding transcription factor activity
JHT10_RS10300	COG2860	membrane
JHT10_RS10305	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JHT10_RS10315	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
JHT10_RS10325	COG0493	'glutamate synthase
JHT10_RS10330	COG0069	glutamate synthase activity
JHT10_RS10330	COG0070	glutamate synthase
JHT10_RS10330	COG0067	glutamate synthase
JHT10_RS10340	COG0069	glutamate synthase activity
JHT10_RS10340	COG0070	glutamate synthase
JHT10_RS10340	COG0067	glutamate synthase
JHT10_RS10345	COG1242	4 iron, 4 sulfur cluster binding
JHT10_RS10350	COG2203	Gaf domain
JHT10_RS10350	COG3706	GGDEF domain
JHT10_RS10350	COG4251	negative regulation of phosphorylation
JHT10_RS10350	COG5001	Diguanylate cyclase
JHT10_RS10355	COG5002	protein histidine kinase activity
JHT10_RS10355	COG2198	Histidine kinase
JHT10_RS10355	COG0784	Response regulator, receiver
JHT10_RS10365	COG0745	RESPONSE REGULATOR receiver
JHT10_RS10375	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
JHT10_RS10390	COG0083	homoserine kinase activity
JHT10_RS10395	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
JHT10_RS10400	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
JHT10_RS10405	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
JHT10_RS10410	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
JHT10_RS10425	COG1115	amino acid carrier protein
JHT10_RS10430	COG3022	response to hydroperoxide
JHT10_RS10435	COG0513	Belongs to the DEAD box helicase family
JHT10_RS10440	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
JHT10_RS10450	COG0716	FMN binding
JHT10_RS10455	COG4974	Belongs to the 'phage' integrase family
JHT10_RS10460	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JHT10_RS10465	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
JHT10_RS10475	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
JHT10_RS10480	COG2204	response regulator
JHT10_RS10490	COG0667	Aldo Keto reductase
JHT10_RS10500	COG3066	DNA modification
JHT10_RS10505	COG0494	nUDIX hydrolase
JHT10_RS10515	COG0730	response to heat
JHT10_RS10520	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
JHT10_RS10525	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
JHT10_RS10535	COG1283	sodium-dependent phosphate transmembrane transporter activity
JHT10_RS10540	COG0583	DNA-binding transcription factor activity
JHT10_RS10545	COG0640	Transcriptional regulator
JHT10_RS10550	COG0268	Binds directly to 16S ribosomal RNA
JHT10_RS10555	COG0728	peptidoglycan biosynthetic process
JHT10_RS10560	COG0196	riboflavin kinase activity
JHT10_RS10565	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JHT10_RS10570	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
JHT10_RS10575	COG1047	Peptidyl-prolyl cis-trans
JHT10_RS10580	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
JHT10_RS10585	COG3279	Response regulator of the LytR AlgR family
JHT10_RS10590	COG3275	phosphorelay sensor kinase activity
JHT10_RS10595	COG1966	Carbon starvation protein
JHT10_RS10610	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
JHT10_RS10615	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
JHT10_RS10620	COG1472	Belongs to the glycosyl hydrolase 3 family
JHT10_RS10625	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
JHT10_RS10630	COG1605	Chorismate mutase
JHT10_RS10630	COG0287	Prephenate dehydrogenase
JHT10_RS10635	COG0739	heme binding
JHT10_RS10645	COG0488	(ABC) transporter
JHT10_RS10655	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
JHT10_RS10660	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
JHT10_RS10665	COG1605	Chorismate mutase
JHT10_RS10665	COG0077	Prephenate dehydratase
JHT10_RS10670	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
JHT10_RS10675	COG0741	lytic transglycosylase activity
JHT10_RS10680	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JHT10_RS10685	COG0564	pseudouridine synthase activity
JHT10_RS10695	COG0542	response to heat
JHT10_RS10750	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
JHT10_RS10755	COG0826	peptidase U32
JHT10_RS10760	COG2974	May be involved in recombination
JHT10_RS10765	COG0745	RESPONSE REGULATOR receiver
JHT10_RS10770	COG5002	protein histidine kinase activity
JHT10_RS10780	COG0248	Ppx GppA phosphatase
JHT10_RS10785	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
JHT10_RS10795	COG0581	inorganic phosphate transmembrane transporter activity
JHT10_RS10800	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JHT10_RS10805	COG0704	Plays a role in the regulation of phosphate uptake
JHT10_RS10815	COG3142	Participates in the control of copper homeostasis
JHT10_RS10820	COG0450	alkyl hydroperoxide reductase
JHT10_RS10825	COG0583	DNA-binding transcription factor activity
JHT10_RS10830	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
JHT10_RS10840	COG0517	IMP dehydrogenase activity
JHT10_RS10850	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
JHT10_RS10855	COG0343	queuine tRNA-ribosyltransferase activity
JHT10_RS10860	COG1862	Preprotein translocase
JHT10_RS10865	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JHT10_RS10870	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JHT10_RS10875	COG0483	inositol monophosphate 1-phosphatase activity
JHT10_RS10890	COG1104	cysteine desulfurase activity
JHT10_RS10895	COG0822	iron-sulfur transferase activity
JHT10_RS10905	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
JHT10_RS10910	COG0443	Heat shock 70 kDa protein
JHT10_RS10915	COG0633	Ferredoxin
JHT10_RS10920	COG2975	iron-sulfur cluster assembly
JHT10_RS10925	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
JHT10_RS10930	COG0105	UTP biosynthetic process
JHT10_RS10935	COG0820	rRNA (adenine-C2-)-methyltransferase activity
JHT10_RS10945	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
JHT10_RS10950	COG0124	histidyl-tRNA synthetase
JHT10_RS10955	COG2976	Protein conserved in bacteria
JHT10_RS10960	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JHT10_RS10965	COG1160	GTP binding
JHT10_RS10980	COG1570	exodeoxyribonuclease VII activity
JHT10_RS10985	COG0516	GMP reductase activity
JHT10_RS10985	COG0517	IMP dehydrogenase activity
JHT10_RS10990	COG0519	Catalyzes the synthesis of GMP from XMP
JHT10_RS10990	COG0518	GMP synthase (glutamine-hydrolyzing) activity
JHT10_RS10995	COG1757	Na H antiporter
JHT10_RS11005	COG1584	GPR1 FUN34 yaaH family protein
JHT10_RS11045	COG2873	o-acetylhomoserine
JHT10_RS11050	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JHT10_RS11070	COG3153	acetyltransferase
JHT10_RS11070	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JHT10_RS11075	COG0583	DNA-binding transcription factor activity
JHT10_RS11135	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
JHT10_RS11140	COG2867	negative regulation of translational initiation
JHT10_RS11145	COG2914	Belongs to the UPF0125 (RnfH) family
JHT10_RS11150	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JHT10_RS11155	COG0497	DNA recombination
JHT10_RS11165	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JHT10_RS11170	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JHT10_RS11180	COG0443	Heat shock 70 kDa protein
JHT10_RS11185	COG0484	heat shock protein binding
JHT10_RS11195	COG4969	Belongs to the N-Me-Phe pilin family
JHT10_RS11215	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
JHT10_RS11225	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
JHT10_RS11230	COG0047	phosphoribosylformylglycinamidine synthase activity
JHT10_RS11230	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JHT10_RS11255	COG2195	Cleaves the N-terminal amino acid of tripeptides
JHT10_RS11260	COG2252	PERMEase
JHT10_RS11265	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
JHT10_RS11270	COG1073	alpha beta
JHT10_RS11280	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
JHT10_RS11285	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
JHT10_RS11290	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
JHT10_RS11295	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JHT10_RS11295	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JHT10_RS11315	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JHT10_RS11320	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
JHT10_RS11325	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
JHT10_RS11330	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
JHT10_RS11335	COG0142	geranyltranstransferase activity
JHT10_RS11340	COG1722	exodeoxyribonuclease VII activity
JHT10_RS11345	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
JHT10_RS11350	COG2885	chlorophyll binding
JHT10_RS11355	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JHT10_RS11355	COG0301	tRNA thio-modification
JHT10_RS11360	COG0583	DNA-binding transcription factor activity
JHT10_RS11370	COG2363	Small membrane protein
JHT10_RS11375	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
JHT10_RS11385	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JHT10_RS11390	COG1611	Belongs to the LOG family
JHT10_RS11405	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
JHT10_RS11405	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
JHT10_RS11415	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
JHT10_RS11420	COG1464	Belongs to the NlpA lipoprotein family
JHT10_RS11425	COG2011	ABC-type metal ion transport system permease component
JHT10_RS11430	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JHT10_RS11435	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
JHT10_RS11445	COG1263	PTS System
JHT10_RS11445	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JHT10_RS11450	COG0366	Alpha amylase catalytic
JHT10_RS11465	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JHT10_RS11470	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JHT10_RS11475	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
JHT10_RS11480	COG0321	lipoyl(octanoyl) transferase activity
JHT10_RS11485	COG2921	Belongs to the UPF0250 family
JHT10_RS11490	COG1686	Belongs to the peptidase S11 family
JHT10_RS11495	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
JHT10_RS11500	COG0772	Belongs to the SEDS family
JHT10_RS11505	COG0768	penicillin binding
JHT10_RS11510	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
JHT10_RS11515	COG0799	negative regulation of ribosome biogenesis
JHT10_RS11520	COG1466	dna polymerase III delta subunit
JHT10_RS11525	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
JHT10_RS11530	COG0495	leucyl-tRNA aminoacylation
JHT10_RS11535	COG2888	peptidyl-tyrosine sulfation
JHT10_RS11540	COG0815	Transfers the fatty acyl group on membrane lipoproteins
JHT10_RS11545	COG4535	Mg2 and Co2 transporter CorC
JHT10_RS11550	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
JHT10_RS11555	COG1702	phosphate starvation-inducible protein PhoH
JHT10_RS11560	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JHT10_RS11565	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JHT10_RS11680	COG0012	GTP binding
JHT10_RS11685	COG0193	aminoacyl-tRNA hydrolase activity
JHT10_RS11690	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JHT10_RS11695	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
JHT10_RS11700	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
JHT10_RS11705	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
JHT10_RS11710	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
JHT10_RS11715	COG2890	protein-(glutamine-N5) methyltransferase activity
JHT10_RS11720	COG3094	Invasion gene expression up-regulator, SirB
JHT10_RS11725	COG2912	Transglutaminase-like superfamily
JHT10_RS11730	COG2877	3-deoxy-8-phosphooctulonate synthase activity
JHT10_RS11735	COG0737	Belongs to the 5'-nucleotidase family
JHT10_RS11745	COG1187	pseudouridine synthase activity
JHT10_RS11750	COG2840	Smr protein MutS2
JHT10_RS11785	COG2217	Heavy metal translocating P-type atpase
JHT10_RS11785	COG2608	mercury ion transmembrane transporter activity
JHT10_RS11795	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
JHT10_RS11800	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JHT10_RS11850	COG0784	Response regulator, receiver
JHT10_RS11850	COG0835	chemotaxis
JHT10_RS11855	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
JHT10_RS11860	COG1815	bacterial-type flagellum-dependent cell motility
JHT10_RS11865	COG1558	bacterial-type flagellum-dependent cell motility
JHT10_RS11875	COG1749	Flagellar hook protein flgE
JHT10_RS11880	COG4787	bacterial-type flagellum-dependent cell motility
JHT10_RS11890	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
JHT10_RS11895	COG1706	bacterial-type flagellum-dependent cell motility
JHT10_RS11900	COG3951	Flagellar rod assembly protein muramidase FlgJ
JHT10_RS11900	COG1705	Flagellar rod assembly protein muramidase FlgJ
JHT10_RS11910	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JHT10_RS11915	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JHT10_RS11920	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JHT10_RS11925	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JHT10_RS11930	COG2190	(PTS) system
JHT10_RS11935	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JHT10_RS11940	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
JHT10_RS11945	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JHT10_RS11950	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
JHT10_RS11955	COG3115	cell septum assembly
JHT10_RS11960	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JHT10_RS11980	COG0330	HflC and HflK could
JHT10_RS11985	COG3118	belongs to the thioredoxin family
JHT10_RS11990	COG0300	oxidoreductase activity
JHT10_RS11995	COG1090	epimerase
JHT10_RS12025	COG0622	Phosphoesterase
JHT10_RS12045	COG3710	Transcriptional regulator
JHT10_RS12050	COG0326	Molecular chaperone. Has ATPase activity
JHT10_RS12055	COG0563	adenylate kinase activity
JHT10_RS12060	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
JHT10_RS12065	COG3104	oligopeptide transport
JHT10_RS12070	COG0250	Participates in transcription elongation, termination and antitermination
JHT10_RS12075	COG0367	asparagine synthase
JHT10_RS12080	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
JHT10_RS12080	COG4651	solute:proton antiporter activity
JHT10_RS12085	COG1846	Transcriptional regulator
JHT10_RS12085	COG1940	carbohydrate kinase activity
JHT10_RS12090	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
JHT10_RS12095	COG1263	PTS System
JHT10_RS12095	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JHT10_RS12100	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JHT10_RS12105	COG0735	belongs to the Fur family
JHT10_RS12115	COG0716	FMN binding
JHT10_RS12125	COG0596	Alpha beta hydrolase
JHT10_RS12130	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
JHT10_RS12135	COG0033	Phosphoglucomutase
JHT10_RS12145	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
JHT10_RS12160	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
JHT10_RS12165	COG1053	succinate dehydrogenase
JHT10_RS12170	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
JHT10_RS12175	COG0567	Dehydrogenase, E1 component
JHT10_RS12180	COG0508	dehydrogenase complex catalyzes the overall conversion of
JHT10_RS12185	COG0045	succinate-CoA ligase (ADP-forming) activity
JHT10_RS12195	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JHT10_RS12200	COG1121	(ABC) transporter
JHT10_RS12205	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
JHT10_RS12210	COG4977	sequence-specific DNA binding
JHT10_RS12215	COG1918	ferrous iron import across plasma membrane
JHT10_RS12235	COG0018	arginyl-trna synthetase
JHT10_RS12240	COG3102	Protein conserved in bacteria
JHT10_RS12245	COG0788	formyltetrahydrofolate deformylase activity
JHT10_RS12250	COG1199	ATP-dependent helicase activity
JHT10_RS12255	COG1214	PFAM Peptidase M22, glycoprotease
JHT10_RS12270	COG2267	carboxylic ester hydrolase activity
JHT10_RS12275	COG0318	PFAM AMP-dependent synthetase and ligase
JHT10_RS12280	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
JHT10_RS12285	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
JHT10_RS12290	COG2894	cell division
JHT10_RS12295	COG0850	regulation of cytokinetic process
JHT10_RS12300	COG3100	YcgL domain-containing protein
JHT10_RS12305	COG2951	lytic endotransglycosylase activity
JHT10_RS12310	COG0583	DNA-binding transcription factor activity
JHT10_RS12315	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JHT10_RS12320	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
JHT10_RS12340	COG1028	Short-chain dehydrogenase reductase Sdr
JHT10_RS12350	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JHT10_RS12375	COG2986	histidine ammonia-lyase
JHT10_RS12380	COG1216	Glycosyl transferase, family 2
JHT10_RS12385	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
JHT10_RS12400	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JHT10_RS12405	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JHT10_RS12440	COG1253	flavin adenine dinucleotide binding
JHT10_RS12445	COG0513	Belongs to the DEAD box helicase family
JHT10_RS12450	COG0569	domain protein
JHT10_RS12455	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JHT10_RS12470	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
JHT10_RS12475	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
JHT10_RS12480	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
JHT10_RS12485	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
JHT10_RS12495	COG2204	response regulator
JHT10_RS12510	COG0544	peptidyl-prolyl cis-trans isomerase activity
JHT10_RS12520	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
JHT10_RS12525	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
JHT10_RS12530	COG0776	regulation of translation
JHT10_RS12535	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JHT10_RS12540	COG1555	photosystem II stabilization
JHT10_RS12555	COG0232	Belongs to the dGTPase family. Type 2 subfamily
JHT10_RS12560	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
JHT10_RS12565	COG0436	Aminotransferase
JHT10_RS12570	COG1169	isochorismate synthase
JHT10_RS12580	COG0596	Alpha beta hydrolase
JHT10_RS12585	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
JHT10_RS12605	COG2855	membrane
JHT10_RS12610	COG0477	Major facilitator Superfamily
JHT10_RS12655	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JHT10_RS12660	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JHT10_RS12685	COG1522	sequence-specific DNA binding
JHT10_RS12695	COG1946	Acyl-CoA thioesterase
JHT10_RS12700	COG3126	Type III secretion system lipoprotein chaperone (YscW)
JHT10_RS12715	COG2199	diguanylate cyclase activity
JHT10_RS12725	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JHT10_RS12730	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
JHT10_RS12735	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
JHT10_RS12740	COG0516	GMP reductase activity
JHT10_RS12740	COG0517	IMP dehydrogenase activity
JHT10_RS12765	COG0537	adenosine 5'-monophosphoramidase activity
JHT10_RS12790	COG3150	esterase
JHT10_RS12795	COG1252	NADH dehydrogenase
JHT10_RS12810	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
JHT10_RS12820	COG4591	ABC-type transport system involved in lipoprotein release permease component
JHT10_RS12825	COG1136	(ABC) transporter
JHT10_RS12830	COG4591	ABC-type transport system involved in lipoprotein release permease component
JHT10_RS12840	COG2333	competence protein COMEC
JHT10_RS12840	COG0658	competence protein
JHT10_RS12845	COG1132	(ABC) transporter
JHT10_RS12850	COG1663	tetraacyldisaccharide 4'-kinase activity
JHT10_RS12860	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
JHT10_RS12865	COG2719	SpoVR family
JHT10_RS12870	COG2718	Belongs to the UPF0229 family
JHT10_RS12875	COG2766	serine protein kinase
JHT10_RS12880	COG3013	Belongs to the UPF0304 family
JHT10_RS12890	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
JHT10_RS12900	COG1882	Formate acetyltransferase
JHT10_RS12940	COG0708	Exodeoxyribonuclease III
JHT10_RS12950	COG3923	Primosomal replication protein n
JHT10_RS12955	COG0730	response to heat
JHT10_RS12960	COG1199	ATP-dependent helicase activity
JHT10_RS12970	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
JHT10_RS12975	COG1187	pseudouridine synthase activity
JHT10_RS12985	COG1278	Cold shock
JHT10_RS12990	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
JHT10_RS12995	COG0542	response to heat
JHT10_RS13005	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
JHT10_RS13010	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
JHT10_RS13015	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
JHT10_RS13025	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
JHT10_RS13035	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JHT10_RS13040	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
JHT10_RS13045	COG0297	glycogen (starch) synthase activity
JHT10_RS13065	COG3070	regulator of competence-specific genes
JHT10_RS13070	COG1609	Transcriptional regulator
JHT10_RS13075	COG3381	protein complex oligomerization
JHT10_RS13080	COG0745	RESPONSE REGULATOR receiver
JHT10_RS13085	COG1434	Gram-negative-bacterium-type cell wall biogenesis
JHT10_RS13090	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
JHT10_RS13095	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
JHT10_RS13100	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
JHT10_RS13105	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
JHT10_RS13125	COG4067	protein conserved in archaea
JHT10_RS13125	COG0189	ligase activity
JHT10_RS13130	COG0500	methyltransferase
JHT10_RS13135	COG4106	trans-aconitate 2-methyltransferase activity
JHT10_RS13140	COG1801	Protein of unknown function DUF72
JHT10_RS13145	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
JHT10_RS13150	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
JHT10_RS13155	COG0840	transmembrane signaling receptor activity
JHT10_RS13160	COG0632	four-way junction helicase activity
JHT10_RS13165	COG2255	four-way junction helicase activity
JHT10_RS13170	COG1271	oxidase subunit
JHT10_RS13175	COG1294	oxidase, subunit
JHT10_RS13180	COG4890	Cyd operon protein YbgT
JHT10_RS13190	COG0824	Thioesterase
JHT10_RS13195	COG0811	peptide transport
JHT10_RS13210	COG0823	Involved in the tonB-independent uptake of proteins
JHT10_RS13215	COG2885	chlorophyll binding
JHT10_RS13220	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
JHT10_RS13225	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
JHT10_RS13235	COG3766	membrane
JHT10_RS13245	COG0754	glutathionylspermidine amidase activity
JHT10_RS13255	COG0784	Response regulator, receiver
JHT10_RS13255	COG5002	protein histidine kinase activity
JHT10_RS13270	COG0840	transmembrane signaling receptor activity
JHT10_RS13275	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JHT10_RS13280	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JHT10_RS13305	COG3568	Endonuclease Exonuclease Phosphatase
JHT10_RS13320	COG0583	DNA-binding transcription factor activity
JHT10_RS13330	COG0686	Belongs to the AlaDH PNT family
JHT10_RS13340	COG1674	ftsk spoiiie
JHT10_RS13345	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
JHT10_RS13350	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
JHT10_RS13355	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
JHT10_RS13370	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
JHT10_RS13375	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JHT10_RS13380	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
JHT10_RS13385	COG0156	8-amino-7-oxononanoate synthase activity
JHT10_RS13395	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
JHT10_RS13405	COG0501	Belongs to the peptidase M48B family
JHT10_RS13415	COG0300	oxidoreductase activity
JHT10_RS13430	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
JHT10_RS13450	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JHT10_RS13455	COG2915	High frequency lysogenization protein hflD homolog
JHT10_RS13460	COG0482	sulfurtransferase activity
JHT10_RS13470	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JHT10_RS13480	COG1757	Na H antiporter
JHT10_RS13495	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
JHT10_RS13500	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
JHT10_RS13505	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JHT10_RS13510	COG0131	Imidazoleglycerol-phosphate dehydratase
JHT10_RS13510	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
JHT10_RS13515	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
JHT10_RS13520	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
JHT10_RS13525	COG0107	imidazoleglycerol-phosphate synthase activity
JHT10_RS13530	COG0140	phosphoribosyl-ATP diphosphatase activity
JHT10_RS13530	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
JHT10_RS13535	COG3012	SEC-C Motif Domain Protein
JHT10_RS13540	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
JHT10_RS13545	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
JHT10_RS13550	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JHT10_RS13555	COG0215	cysteine-tRNA ligase activity
JHT10_RS13560	COG1435	thymidine kinase activity
JHT10_RS13565	COG1434	Gram-negative-bacterium-type cell wall biogenesis
JHT10_RS13590	COG2116	formate transmembrane transporter activity
JHT10_RS13600	COG0390	transport system, permease component
JHT10_RS13605	COG4459	periplasmic nitrate reductase
JHT10_RS13610	COG3005	denitrification pathway
JHT10_RS13615	COG0243	molybdopterin cofactor binding
JHT10_RS13630	COG1227	inorganic diphosphatase activity
JHT10_RS13640	COG4172	Belongs to the ABC transporter superfamily
JHT10_RS13650	COG4171	peptide transport system, permease
JHT10_RS13665	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
JHT10_RS13670	COG1842	Phage shock protein A
JHT10_RS13685	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JHT10_RS13700	COG2818	Glycosylase
JHT10_RS13705	COG5380	lipid catabolic process
JHT10_RS13710	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
JHT10_RS13715	COG0626	cystathionine gamma-synthase activity
JHT10_RS13725	COG0733	neurotransmitter:sodium symporter activity
JHT10_RS13735	COG0564	pseudouridine synthase activity
JHT10_RS13745	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JHT10_RS13750	COG1151	hydroxylamine reductase activity
JHT10_RS13755	COG3604	Transcriptional regulator
JHT10_RS13765	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JHT10_RS13770	COG4136	ATPase activity
JHT10_RS13775	COG4135	transport system, permease component
JHT10_RS13780	COG4134	Bacterial extracellular solute-binding protein
JHT10_RS13785	COG0398	Pfam SNARE associated Golgi protein
JHT10_RS13795	COG0493	'glutamate synthase
JHT10_RS13820	COG3313	Fe-S protein
JHT10_RS13850	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
JHT10_RS13870	COG1061	Type III restriction enzyme res subunit
JHT10_RS13875	COG1187	pseudouridine synthase activity
JHT10_RS13880	COG2814	Major facilitator Superfamily
JHT10_RS13910	COG3005	denitrification pathway
JHT10_RS13915	COG0702	epimerase
JHT10_RS13920	COG0534	Mate efflux family protein
JHT10_RS13925	COG4181	ATPase activity
JHT10_RS13940	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
JHT10_RS13955	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
JHT10_RS13960	COG3273	potassium ion transport
JHT10_RS13960	COG2985	domain, Protein
JHT10_RS13965	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
JHT10_RS13975	COG1737	Transcriptional regulator
JHT10_RS13980	COG0076	glutamate decarboxylase activity
JHT10_RS13990	COG2431	L-lysine efflux transmembrane transporter activity
JHT10_RS14000	COG3070	regulator of competence-specific genes
JHT10_RS14015	COG4191	Histidine kinase
JHT10_RS14015	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JHT10_RS14025	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
JHT10_RS14030	COG3048	D-serine ammonia-lyase activity
JHT10_RS14035	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
JHT10_RS14040	COG4988	ABC transporter
JHT10_RS14045	COG0492	ferredoxin-NADP+ reductase activity
JHT10_RS14070	COG0471	metal ion transport
JHT10_RS14075	COG2949	membrane
JHT10_RS14080	COG0281	malic enzyme
JHT10_RS14085	COG1643	Atp-dependent helicase
JHT10_RS14090	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
JHT10_RS14105	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
JHT10_RS14140	COG0247	lactate metabolic process
JHT10_RS14140	COG0277	FAD linked oxidase domain protein
JHT10_RS14155	COG2986	histidine ammonia-lyase
JHT10_RS14160	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
JHT10_RS14165	COG0010	Belongs to the arginase family
JHT10_RS14170	COG1228	amidohydrolase
JHT10_RS14175	COG2188	Transcriptional regulator
JHT10_RS14190	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JHT10_RS14200	COG0291	Belongs to the bacterial ribosomal protein bL35 family
JHT10_RS14210	COG0393	Putative heavy-metal-binding
JHT10_RS14240	COG3706	GGDEF domain
JHT10_RS14245	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
JHT10_RS14250	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JHT10_RS14250	COG0072	phenylalanine-tRNA ligase activity
JHT10_RS14260	COG0776	regulation of translation
JHT10_RS14270	COG0500	methyltransferase
JHT10_RS14275	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
JHT10_RS14280	COG0295	cytidine deaminase activity
JHT10_RS14285	COG1346	cytolysis
JHT10_RS14290	COG1380	Effector of murein hydrolase LrgA
JHT10_RS14295	COG2925	Exonuclease
JHT10_RS14300	COG1823	symporter activity
JHT10_RS14305	COG0702	epimerase
JHT10_RS14310	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
JHT10_RS14315	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
JHT10_RS14325	COG2062	phosphohistidine phosphatase, SixA
JHT10_RS14335	COG2988	succinylglutamate desuccinylase activity
JHT10_RS14340	COG4139	cobalamin transport
JHT10_RS14345	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
JHT10_RS14365	COG0583	DNA-binding transcription factor activity
JHT10_RS14385	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
JHT10_RS14390	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JHT10_RS14395	COG3475	LICD family
JHT10_RS14400	COG1451	nucleotide metabolic process
JHT10_RS14405	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
JHT10_RS14435	COG3938	Belongs to the proline racemase family
JHT10_RS14450	COG2423	ornithine cyclodeaminase activity
JHT10_RS14455	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JHT10_RS14460	COG3842	ATPase activity
JHT10_RS14465	COG1176	ABC-type spermidine putrescine transport system, permease component I
JHT10_RS14470	COG1177	transmembrane transport
JHT10_RS14480	COG3291	Pkd domain containing protein
JHT10_RS14500	COG0444	Belongs to the ABC transporter superfamily
JHT10_RS14505	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JHT10_RS14510	COG0601	transmembrane transport
JHT10_RS14520	COG2195	Cleaves the N-terminal amino acid of tripeptides
JHT10_RS14530	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
JHT10_RS14540	COG0625	glutathione transferase activity
JHT10_RS14605	COG0583	DNA-binding transcription factor activity
JHT10_RS14640	COG0471	metal ion transport
JHT10_RS14645	COG4191	Histidine kinase
JHT10_RS14645	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JHT10_RS14655	COG3300	MHYT domain
JHT10_RS14655	COG5001	Diguanylate cyclase
JHT10_RS14665	COG1280	lysine exporter protein (LysE YggA)
JHT10_RS14670	COG1328	CTP reductase activity
JHT10_RS14675	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
JHT10_RS14685	COG0861	Integral membrane protein TerC family
JHT10_RS14690	COG0739	heme binding
JHT10_RS14735	COG3501	Rhs element vgr protein
JHT10_RS14760	COG0515	serine threonine protein kinase
JHT10_RS14795	COG1522	sequence-specific DNA binding
JHT10_RS14885	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
JHT10_RS14895	COG0814	amino acid
JHT10_RS14915	COG1132	(ABC) transporter
JHT10_RS14920	COG1132	(ABC) transporter
JHT10_RS14945	COG0443	Heat shock 70 kDa protein
JHT10_RS14950	COG0443	Heat shock 70 kDa protein
JHT10_RS14960	COG3706	GGDEF domain
JHT10_RS14990	COG0243	molybdopterin cofactor binding
JHT10_RS14995	COG0437	4 iron, 4 sulfur cluster binding
JHT10_RS15000	COG3302	dmso reductase anchor subunit
JHT10_RS15015	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
JHT10_RS15020	COG1643	Atp-dependent helicase
JHT10_RS15035	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JHT10_RS15045	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
JHT10_RS15050	COG1215	transferase activity, transferring glycosyl groups
JHT10_RS15055	COG0438	transferase activity, transferring glycosyl groups
JHT10_RS15085	COG0438	transferase activity, transferring glycosyl groups
JHT10_RS15095	COG2204	response regulator
JHT10_RS15125	COG1793	dna ligase
JHT10_RS15135	COG0534	Mate efflux family protein
JHT10_RS15140	COG0307	riboflavin synthase, alpha
JHT10_RS15150	COG3001	Fructosamine kinase
JHT10_RS15155	COG2201	protein-glutamate methylesterase activity
JHT10_RS15160	COG3706	GGDEF domain
JHT10_RS15170	COG0791	NLP P60 protein
JHT10_RS15175	COG0840	transmembrane signaling receptor activity
JHT10_RS15175	COG3290	protein histidine kinase activity
JHT10_RS15210	COG3148	PFAM DTW domain containing protein
JHT10_RS15215	COG1940	carbohydrate kinase activity
JHT10_RS15225	COG0303	'Molybdopterin
JHT10_RS15230	COG0746	molybdenum cofactor guanylyltransferase activity
JHT10_RS15235	COG3842	ATPase activity
JHT10_RS15250	COG2204	response regulator
JHT10_RS15255	COG4191	Histidine kinase
JHT10_RS15260	COG0488	(ABC) transporter
JHT10_RS15265	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
JHT10_RS15285	COG3381	protein complex oligomerization
JHT10_RS15295	COG3383	formate dehydrogenase (NAD+) activity
JHT10_RS15295	COG0243	molybdopterin cofactor binding
JHT10_RS15300	COG0437	4 iron, 4 sulfur cluster binding
JHT10_RS15325	COG0004	ammonium transporteR
JHT10_RS15335	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
JHT10_RS15340	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
JHT10_RS15350	COG1177	transmembrane transport
JHT10_RS15360	COG3842	ATPase activity
JHT10_RS15380	COG0037	tRNA processing
JHT10_RS15385	COG0589	response to stress
JHT10_RS15390	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JHT10_RS15405	COG2217	Heavy metal translocating P-type atpase
JHT10_RS15415	COG2010	Cytochrome c
JHT10_RS15430	COG3278	Belongs to the heme-copper respiratory oxidase family
JHT10_RS15445	COG0784	Response regulator, receiver
JHT10_RS15445	COG2205	protein histidine kinase activity
JHT10_RS15480	COG3120	sequence-specific DNA binding
JHT10_RS15485	COG1067	ATP-dependent peptidase activity
JHT10_RS15490	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
JHT10_RS15505	COG0488	(ABC) transporter
JHT10_RS15515	COG0116	Belongs to the methyltransferase superfamily
JHT10_RS15515	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
JHT10_RS15525	COG0167	dihydroorotate dehydrogenase activity
JHT10_RS15530	COG2902	Dehydrogenase
JHT10_RS15540	COG0308	aminopeptidase N
JHT10_RS15555	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
JHT10_RS15560	COG1956	GAF domain-containing protein
JHT10_RS15565	COG1132	(ABC) transporter
JHT10_RS15570	COG2995	paraquat-inducible protein a
JHT10_RS15575	COG3008	intermembrane lipid transfer
JHT10_RS15580	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JHT10_RS15580	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
JHT10_RS15600	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
JHT10_RS15605	COG1666	GTP binding
JHT10_RS15615	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JHT10_RS15620	COG4597	amino acid ABC transporter
JHT10_RS15625	COG0765	amino acid transport
JHT10_RS15630	COG1126	abc transporter atp-binding protein
JHT10_RS15635	COG0670	Belongs to the BI1 family
JHT10_RS15645	COG2920	part of a sulfur-relay system
JHT10_RS15650	COG1254	Belongs to the acylphosphatase family
JHT10_RS15655	COG0840	transmembrane signaling receptor activity
JHT10_RS15660	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
JHT10_RS15700	COG3706	GGDEF domain
JHT10_RS15705	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
JHT10_RS15710	COG0602	queuosine metabolic process
JHT10_RS15715	COG0561	phosphatase activity
JHT10_RS15740	COG2828	Protein conserved in bacteria
JHT10_RS15750	COG0372	Belongs to the citrate synthase family
JHT10_RS15755	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
JHT10_RS15785	COG0730	response to heat
JHT10_RS15805	COG0457	Tetratricopeptide repeat
JHT10_RS15875	COG4790	Type iii secretion
JHT10_RS15880	COG4794	Type iii secretion
JHT10_RS15885	COG4791	protein targeting
JHT10_RS15890	COG4792	protein secretion
JHT10_RS15900	COG1073	alpha beta
JHT10_RS15905	COG1073	alpha beta
JHT10_RS15915	COG0583	DNA-binding transcription factor activity
JHT10_RS15950	COG3177	Filamentation induced by cAMP protein fic
JHT10_RS15970	COG4669	(LipO)protein
JHT10_RS16040	COG1012	belongs to the aldehyde dehydrogenase family
JHT10_RS16045	COG3284	Transcriptional regulator
JHT10_RS16060	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
JHT10_RS16065	COG0363	glucosamine-6-phosphate deaminase activity
JHT10_RS16070	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
JHT10_RS16075	COG4565	transcriptional regulatory protein
JHT10_RS16080	COG3290	protein histidine kinase activity
JHT10_RS16095	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JHT10_RS16110	COG1858	cytochrome C peroxidase
JHT10_RS16115	COG0527	aspartate kinase activity
JHT10_RS16120	COG0662	Cupin 2, conserved barrel domain protein
JHT10_RS16125	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JHT10_RS16130	COG0456	acetyltransferase
JHT10_RS16135	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JHT10_RS16155	COG4176	ABC-type proline glycine betaine transport system permease component
JHT10_RS16160	COG2113	Glycine betaine
JHT10_RS16180	COG1028	Short-chain dehydrogenase reductase Sdr
JHT10_RS16190	COG0745	RESPONSE REGULATOR receiver
JHT10_RS16195	COG0642	Histidine kinase
JHT10_RS16200	COG1368	sulfuric ester hydrolase activity
JHT10_RS16225	COG1115	amino acid carrier protein
JHT10_RS16235	COG1280	lysine exporter protein (LysE YggA)
JHT10_RS16240	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
JHT10_RS16245	COG1560	Kdo2-lipid A biosynthetic process
JHT10_RS16250	COG0531	amino acid
JHT10_RS16260	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
JHT10_RS16265	COG3063	Type IV pilus biogenesis stability protein PilW
JHT10_RS16295	COG0110	maltose O-acetyltransferase activity
JHT10_RS16315	COG2315	Protein conserved in bacteria
JHT10_RS16320	COG1846	Transcriptional regulator
JHT10_RS16335	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JHT10_RS16345	COG2200	EAL domain
JHT10_RS16345	COG2771	luxR family
JHT10_RS16350	COG1227	inorganic diphosphatase activity
JHT10_RS16355	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JHT10_RS16360	COG1012	belongs to the aldehyde dehydrogenase family
JHT10_RS16365	COG2957	Belongs to the agmatine deiminase family
JHT10_RS16375	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JHT10_RS16380	COG1012	belongs to the aldehyde dehydrogenase family
JHT10_RS16385	COG1917	Cupin 2, conserved barrel domain protein
JHT10_RS16385	COG1396	sequence-specific DNA binding
JHT10_RS16390	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
JHT10_RS16395	COG0174	glutamine synthetase
JHT10_RS16400	COG1757	Na H antiporter
JHT10_RS16460	COG2026	Addiction module toxin, RelE StbE family
JHT10_RS16475	COG0653	protein targeting
JHT10_RS16515	COG0456	acetyltransferase
JHT10_RS16515	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
JHT10_RS16575	COG0251	oxidation-reduction process
JHT10_RS16660	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
JHT10_RS16665	COG2194	sulfuric ester hydrolase activity
JHT10_RS16680	COG3422	double-strand break repair
JHT10_RS16710	COG0582	viral genome integration into host DNA
JHT10_RS16720	COG1280	lysine exporter protein (LysE YggA)
JHT10_RS16790	COG0456	acetyltransferase
JHT10_RS16870	COG1280	lysine exporter protein (LysE YggA)
JHT10_RS16880	COG1280	lysine exporter protein (LysE YggA)
JHT10_RS17070	COG0454	-acetyltransferase
JHT10_RS17085	COG0456	acetyltransferase
JHT10_RS17115	COG0346	lactoylglutathione lyase activity
JHT10_RS17125	COG0251	oxidation-reduction process
JHT10_RS17345	COG0346	lactoylglutathione lyase activity
JHT10_RS17510	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JHT10_RS17520	COG3768	UPF0283 membrane protein
JHT10_RS17525	COG3106	COG3106 Predicted ATPase
JHT10_RS17540	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JHT10_RS17545	COG0784	Response regulator, receiver
JHT10_RS17545	COG2205	protein histidine kinase activity
JHT10_RS17555	COG0494	nUDIX hydrolase
JHT10_RS17560	COG0814	amino acid
JHT10_RS17565	COG1760	l-serine dehydratase
JHT10_RS17570	COG2200	EAL domain
JHT10_RS17580	COG0720	synthase
JHT10_RS17590	COG0017	Asparaginyl-tRNA synthetase
JHT10_RS17600	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JHT10_RS17615	COG1448	Aminotransferase
JHT10_RS17635	COG0840	transmembrane signaling receptor activity
JHT10_RS17640	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JHT10_RS17645	COG1846	Transcriptional regulator
JHT10_RS17670	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
JHT10_RS17685	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JHT10_RS17690	COG3108	Peptidase M15
JHT10_RS17695	COG2989	Protein conserved in bacteria
JHT10_RS17720	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JHT10_RS17730	COG3088	subunit of a heme lyase
JHT10_RS17730	COG4235	cytochrome complex assembly
JHT10_RS17740	COG1138	Cytochrome C-type biogenesis protein
JHT10_RS17745	COG3301	Polysulphide reductase, NrfD
JHT10_RS17750	COG0437	4 iron, 4 sulfur cluster binding
JHT10_RS17760	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
JHT10_RS17780	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
JHT10_RS17785	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JHT10_RS17790	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JHT10_RS17815	COG0019	diaminopimelate decarboxylase activity
JHT10_RS17855	COG0322	excinuclease ABC activity
JHT10_RS17860	COG2197	response regulator
JHT10_RS17865	COG0417	DNA replication proofreading
JHT10_RS17875	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JHT10_RS17880	COG3099	Belongs to the UPF0263 family
JHT10_RS17885	COG1187	pseudouridine synthase activity
JHT10_RS17895	COG0009	L-threonylcarbamoyladenylate synthase
JHT10_RS17900	COG0613	PHP domain protein
JHT10_RS17910	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JHT10_RS17915	COG0512	Glutamine amidotransferase of anthranilate synthase
JHT10_RS17920	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
JHT10_RS17925	COG0134	indole-3-glycerol-phosphate synthase activity
JHT10_RS17925	COG0135	phosphoribosylanthranilate isomerase activity
JHT10_RS17930	COG0133	tryptophan synthase activity
JHT10_RS17935	COG0159	tryptophan synthase activity
JHT10_RS17940	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JHT10_RS17945	COG0318	PFAM AMP-dependent synthetase and ligase
JHT10_RS17950	COG1301	dicarboxylic acid transport
JHT10_RS17970	COG2917	probably involved in intracellular septation
JHT10_RS17980	COG2350	Protein conserved in bacteria
JHT10_RS17990	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JHT10_RS17995	COG0583	DNA-binding transcription factor activity
JHT10_RS18010	COG5001	Diguanylate cyclase
JHT10_RS18010	COG2203	Gaf domain
JHT10_RS18010	COG3706	GGDEF domain
JHT10_RS18010	COG4251	negative regulation of phosphorylation
JHT10_RS18015	COG1032	radical SAM domain protein
JHT10_RS18020	COG0840	transmembrane signaling receptor activity
JHT10_RS18025	COG0745	RESPONSE REGULATOR receiver
JHT10_RS18030	COG3850	Histidine kinase
JHT10_RS18030	COG5002	protein histidine kinase activity
JHT10_RS18080	COG1335	isochorismatase
JHT10_RS18085	COG1136	(ABC) transporter
JHT10_RS18085	COG0577	efflux transmembrane transporter activity
JHT10_RS18090	COG1136	(ABC) transporter
JHT10_RS18090	COG0577	efflux transmembrane transporter activity
JHT10_RS18095	COG1136	(ABC) transporter
JHT10_RS18095	COG0577	efflux transmembrane transporter activity
JHT10_RS18105	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JHT10_RS18135	COG3118	belongs to the thioredoxin family
JHT10_RS18140	COG4232	protein-disulfide reductase activity
JHT10_RS18180	COG2863	cytochrome
JHT10_RS18185	COG3258	Cytochrome c
JHT10_RS18190	COG2995	paraquat-inducible protein a
JHT10_RS18195	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
JHT10_RS18195	COG3008	intermembrane lipid transfer
JHT10_RS18205	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
JHT10_RS18230	COG4166	transmembrane transport
JHT10_RS18235	COG0284	orotidine-5'-phosphate decarboxylase activity
JHT10_RS18240	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
JHT10_RS18245	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
JHT10_RS18255	COG0539	negative regulation of cytoplasmic translation
JHT10_RS18260	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
JHT10_RS18265	COG0616	signal peptide processing
JHT10_RS18270	COG1028	Short-chain dehydrogenase reductase Sdr
JHT10_RS18285	COG0587	DNA-directed DNA polymerase activity
JHT10_RS18290	COG0784	Response regulator, receiver
JHT10_RS18290	COG0835	chemotaxis
JHT10_RS18295	COG1940	carbohydrate kinase activity
JHT10_RS18300	COG0469	pyruvate kinase activity
JHT10_RS18305	COG4667	esterase of the alpha-beta hydrolase superfamily
JHT10_RS18320	COG0733	neurotransmitter:sodium symporter activity
JHT10_RS18335	COG1263	PTS System
JHT10_RS18335	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JHT10_RS18340	COG0084	hydrolase, TatD family'
JHT10_RS18350	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
JHT10_RS18355	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
JHT10_RS18385	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JHT10_RS18390	COG0416	fatty acid biosynthetic process
JHT10_RS18400	COG1399	metal-binding, possibly nucleic acid-binding protein
JHT10_RS18405	COG0424	maF-like protein
JHT10_RS18410	COG0564	pseudouridine synthase activity
JHT10_RS18415	COG1530	ribonuclease E activity
JHT10_RS18420	COG0659	secondary active sulfate transmembrane transporter activity
JHT10_RS18425	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JHT10_RS18430	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
JHT10_RS18440	COG0572	uridine kinase
JHT10_RS18445	COG0489	protein tyrosine kinase activity
JHT10_RS18450	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JHT10_RS18450	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JHT10_RS18460	COG2186	Transcriptional regulator
JHT10_RS18465	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
JHT10_RS18470	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
JHT10_RS18475	COG0653	protein targeting
JHT10_RS18480	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JHT10_RS18490	COG0366	Alpha amylase catalytic
JHT10_RS18495	COG1122	ATPase activity
JHT10_RS18500	COG4120	Belongs to the binding-protein-dependent transport system permease family
JHT10_RS18510	COG3092	negative regulation of chromosome organization
JHT10_RS18515	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JHT10_RS18520	COG0280	phosphate acetyltransferase
JHT10_RS18520	COG0857	belongs to the CobB CobQ family
JHT10_RS18525	COG3174	membrane
JHT10_RS18535	COG0435	Glutathione S-transferase
JHT10_RS18545	COG0444	Belongs to the ABC transporter superfamily
JHT10_RS18550	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JHT10_RS18555	COG0601	transmembrane transport
JHT10_RS18565	COG0314	molybdopterin synthase activity
JHT10_RS18570	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
JHT10_RS18575	COG0315	cyclic pyranopterin monophosphate synthase activity
JHT10_RS18580	COG0521	Mo-molybdopterin cofactor biosynthetic process
JHT10_RS18585	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
JHT10_RS18590	COG0391	Required for morphogenesis under gluconeogenic growth conditions
JHT10_RS18595	COG2198	Histidine kinase
JHT10_RS18600	COG2204	response regulator
JHT10_RS18605	COG0556	nucleotide-excision repair
JHT10_RS18615	COG4657	Part of a membrane complex involved in electron transport
JHT10_RS18620	COG2878	Part of a membrane complex involved in electron transport
JHT10_RS18625	COG4656	Part of a membrane complex involved in electron transport
JHT10_RS18630	COG4658	electron transport chain
JHT10_RS18635	COG4659	FMN binding
JHT10_RS18640	COG4660	Part of a membrane complex involved in electron transport
JHT10_RS18645	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JHT10_RS18650	COG0346	lactoylglutathione lyase activity
JHT10_RS18660	COG2885	chlorophyll binding
JHT10_RS18665	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
JHT10_RS18670	COG2056	Na+-H+ antiporter family
JHT10_RS18680	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
JHT10_RS18700	COG1012	belongs to the aldehyde dehydrogenase family
JHT10_RS18700	COG1454	alcohol dehydrogenase
JHT10_RS18705	COG2095	MarC family integral membrane protein
JHT10_RS18710	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JHT10_RS18715	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JHT10_RS18720	COG1757	Na H antiporter
JHT10_RS18735	COG3081	Nucleoid-associated protein
JHT10_RS18740	COG3082	Protein of unknown function (DUF1414)
JHT10_RS18745	COG3083	sulfuric ester hydrolase activity
JHT10_RS18755	COG0123	including yeast histone deacetylase and acetoin utilization protein
JHT10_RS18770	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JHT10_RS18775	COG0778	Nitroreductase
JHT10_RS18780	COG0446	pyridine nucleotide-disulphide oxidoreductase
JHT10_RS18780	COG1902	pentaerythritol trinitrate reductase activity
JHT10_RS18785	COG0616	signal peptide processing
JHT10_RS18790	COG0252	asparaginase activity
JHT10_RS18795	COG3139	Protein of unknown function (DUF1315)
JHT10_RS18805	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JHT10_RS18810	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
JHT10_RS18825	COG2226	methyltransferase
JHT10_RS18840	COG1785	Belongs to the alkaline phosphatase family
JHT10_RS18850	COG0346	lactoylglutathione lyase activity
JHT10_RS18855	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
JHT10_RS18860	COG0668	transmembrane transport
JHT10_RS18865	COG2983	Belongs to the UPF0260 family
JHT10_RS18870	COG2261	transglycosylase associated protein
JHT10_RS18885	COG3681	Belongs to the UPF0597 family
JHT10_RS18890	COG0251	oxidation-reduction process
JHT10_RS18895	COG0814	amino acid
JHT10_RS18900	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
JHT10_RS18905	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
JHT10_RS18910	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
JHT10_RS18920	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JHT10_RS18925	COG2832	Protein of unknown function (DUF454)
JHT10_RS18930	COG0745	RESPONSE REGULATOR receiver
JHT10_RS18935	COG0583	DNA-binding transcription factor activity
JHT10_RS18945	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
JHT10_RS18950	COG1286	toxin biosynthetic process
JHT10_RS18955	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
JHT10_RS18960	COG0285	dihydrofolate synthase activity
JHT10_RS18965	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
JHT10_RS18970	COG0101	tRNA pseudouridine synthase activity
JHT10_RS18980	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JHT10_RS18985	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JHT10_RS18990	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JHT10_RS18995	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JHT10_RS18995	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
JHT10_RS19000	COG0431	NADPH-dependent FMN reductase
JHT10_RS19010	COG3101	peptidyl-lysine hydroxylation
JHT10_RS19015	COG2860	membrane
JHT10_RS19020	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
JHT10_RS19025	COG2890	protein-(glutamine-N5) methyltransferase activity
JHT10_RS19030	COG2840	Smr protein MutS2
JHT10_RS19035	COG2062	phosphohistidine phosphatase, SixA
JHT10_RS19050	COG1250	3-hydroxyacyl-CoA dehydrogenase
JHT10_RS19050	COG1024	Enoyl-CoA hydratase
JHT10_RS19055	COG0183	Belongs to the thiolase family
JHT10_RS19070	COG2067	long-chain fatty acid transport protein
JHT10_RS19080	COG2853	Lipoprotein
JHT10_RS19095	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JHT10_RS19100	COG1138	Cytochrome C-type biogenesis protein
JHT10_RS19105	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
JHT10_RS19110	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JHT10_RS19115	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JHT10_RS19120	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JHT10_RS19125	COG4133	protoheme IX ABC transporter activity
JHT10_RS19135	COG0835	chemotaxis
JHT10_RS19145	COG1192	Involved in chromosome partitioning
JHT10_RS19150	COG2201	protein-glutamate methylesterase activity
JHT10_RS19155	COG2198	Histidine kinase
JHT10_RS19155	COG0643	Histidine kinase
JHT10_RS19155	COG0784	Response regulator, receiver
JHT10_RS19160	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
JHT10_RS19200	COG1987	bacterial-type flagellum assembly
JHT10_RS19250	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
JHT10_RS19260	COG1677	Flagellar hook-basal body complex protein FliE
JHT10_RS19280	COG1516	flagellar protein fliS
JHT10_RS19290	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
JHT10_RS19295	COG1334	flagellar protein FlaG
JHT10_RS19300	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JHT10_RS19305	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JHT10_RS19310	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JHT10_RS19315	COG2837	iron assimilation
JHT10_RS19340	COG1393	Belongs to the ArsC family
JHT10_RS19345	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JHT10_RS19360	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
JHT10_RS19365	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JHT10_RS19370	COG2716	regulation of RNA biosynthetic process
JHT10_RS19375	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
JHT10_RS19390	COG4783	chaperone-mediated protein folding
JHT10_RS19395	COG1393	Belongs to the ArsC family
JHT10_RS19415	COG2233	PERMEase
JHT10_RS19420	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
JHT10_RS19425	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
JHT10_RS19430	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
JHT10_RS19435	COG0121	glutamine amidotransferase
JHT10_RS19440	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
JHT10_RS19445	COG1960	acyl-CoA dehydrogenase activity
JHT10_RS19460	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
JHT10_RS19465	COG0328	RNA-DNA hybrid ribonuclease activity
JHT10_RS19470	COG2226	methyltransferase
JHT10_RS19475	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JHT10_RS19480	COG0741	lytic transglycosylase activity
JHT10_RS19480	COG1388	LysM domain
JHT10_RS19490	COG3021	interspecies interaction between organisms
JHT10_RS19495	COG0347	Belongs to the P(II) protein family
JHT10_RS19505	COG0037	tRNA processing
JHT10_RS19510	COG0825	malonyl-CoA metabolic process
JHT10_RS19515	COG0587	DNA-directed DNA polymerase activity
JHT10_RS19520	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JHT10_RS19525	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
JHT10_RS19530	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
JHT10_RS19535	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
JHT10_RS19540	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
JHT10_RS19545	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
JHT10_RS19555	COG0750	zinc metalloprotease
JHT10_RS19560	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
JHT10_RS19565	COG0575	Belongs to the CDS family
JHT10_RS19570	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JHT10_RS19575	COG0233	cytoplasmic translational termination
JHT10_RS19580	COG0528	UMP kinase activity
JHT10_RS19585	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
JHT10_RS19590	COG0052	Belongs to the universal ribosomal protein uS2 family
JHT10_RS19595	COG0024	Methionine aminopeptidase
JHT10_RS19600	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
JHT10_RS19610	COG0564	pseudouridine synthase activity
JHT10_RS19615	COG3098	single-species biofilm formation
JHT10_RS19640	COG1671	Belongs to the UPF0178 family
JHT10_RS19645	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
JHT10_RS19655	COG0254	rRNA binding
JHT10_RS19660	COG1720	tRNA m6t6A37 methyltransferase activity
JHT10_RS19665	COG0442	prolyl-tRNA aminoacylation
JHT10_RS19685	COG0733	neurotransmitter:sodium symporter activity
JHT10_RS19700	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JHT10_RS19705	COG0514	ATP-dependent DNA helicase (RecQ)
JHT10_RS19710	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JHT10_RS19725	COG1477	protein flavinylation
JHT10_RS19730	COG2871	sodium ion transport
JHT10_RS19735	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
JHT10_RS19740	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
JHT10_RS19745	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
JHT10_RS19750	COG1805	sodium ion transport
JHT10_RS19755	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
JHT10_RS19760	COG0271	Belongs to the BolA IbaG family
JHT10_RS19765	COG2813	Specifically methylates the guanine in position
JHT10_RS19770	COG3056	Lipoprotein
JHT10_RS19790	COG1595	DNA-templated transcription, initiation
JHT10_RS19810	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JHT10_RS19815	COG0693	protein deglycase activity
JHT10_RS19820	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JHT10_RS19825	COG3706	GGDEF domain
JHT10_RS19830	COG2166	iron-sulfur cluster assembly
JHT10_RS19835	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
JHT10_RS19840	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
JHT10_RS19850	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
JHT10_RS19850	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
JHT10_RS19860	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
JHT10_RS19865	COG1074	ATP-dependent DNA helicase activity
JHT10_RS19870	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
JHT10_RS19890	COG3141	response to X-ray
JHT10_RS19895	COG2171	N-acyltransferase activity
JHT10_RS19900	COG0584	glycerophosphoryl diester phosphodiesterase
JHT10_RS19905	COG2271	Major facilitator Superfamily
JHT10_RS19910	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
JHT10_RS19915	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
JHT10_RS19925	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
JHT10_RS19930	COG0598	Magnesium transport protein CorA
JHT10_RS19945	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JHT10_RS19950	COG1609	Transcriptional regulator
JHT10_RS19955	COG2176	DNA-directed DNA polymerase activity
JHT10_RS19970	COG2017	converts alpha-aldose to the beta-anomer
JHT10_RS19975	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
JHT10_RS19980	COG1085	galactose-1-phosphate uridylyltransferase
JHT10_RS19985	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JHT10_RS19990	COG1609	Transcriptional regulator
JHT10_RS19995	COG3250	beta-galactosidase activity
JHT10_RS20000	COG2731	YhcH YjgK YiaL family protein
JHT10_RS20005	COG0531	amino acid
JHT10_RS20010	COG0583	DNA-binding transcription factor activity
JHT10_RS20070	COG4964	Belongs to the GSP D family
JHT10_RS20095	COG2169	Transcriptional regulator
JHT10_RS20100	COG1022	Amp-dependent synthetase and ligase
JHT10_RS20110	COG0583	DNA-binding transcription factor activity
JHT10_RS20115	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JHT10_RS20120	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
JHT10_RS20130	COG0560	Phosphoserine phosphatase
JHT10_RS20140	COG0813	purine-nucleoside phosphorylase activity
JHT10_RS20145	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
JHT10_RS20150	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
JHT10_RS20155	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
JHT10_RS20160	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JHT10_RS20165	COG0084	hydrolase, TatD family'
JHT10_RS20175	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
JHT10_RS20195	COG3153	acetyltransferase
JHT10_RS20200	COG3154	lipid carrier protein
JHT10_RS20210	COG0826	peptidase U32
JHT10_RS20215	COG0826	peptidase U32
JHT10_RS20220	COG0534	Mate efflux family protein
JHT10_RS20235	COG1185	polyribonucleotide nucleotidyltransferase activity
JHT10_RS20240	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
JHT10_RS20245	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
JHT10_RS20250	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
JHT10_RS20255	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
JHT10_RS20260	COG0195	Participates in both transcription termination and antitermination
JHT10_RS20265	COG0779	Required for maturation of 30S ribosomal subunits
JHT10_RS20280	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
JHT10_RS20285	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JHT10_RS20290	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
JHT10_RS20295	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JHT10_RS20300	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
JHT10_RS20305	COG1534	Rna-binding protein
JHT10_RS20310	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JHT10_RS20315	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
JHT10_RS20320	COG2027	D-alanyl-D-alanine carboxypeptidase
JHT10_RS20330	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JHT10_RS20335	COG0739	heme binding
JHT10_RS20340	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JHT10_RS20350	COG0316	Belongs to the HesB IscA family
JHT10_RS20355	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
JHT10_RS20360	COG0628	permease
JHT10_RS20365	COG2813	Specifically methylates the guanine in position
JHT10_RS20370	COG0784	Response regulator, receiver
JHT10_RS20370	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JHT10_RS20370	COG2198	Histidine kinase
JHT10_RS20370	COG2205	protein histidine kinase activity
JHT10_RS20375	COG0747	negative chemotaxis
JHT10_RS20385	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JHT10_RS20390	COG0444	Belongs to the ABC transporter superfamily
JHT10_RS20395	COG4608	Belongs to the ABC transporter superfamily
JHT10_RS20405	COG2971	BadF BadG BcrA BcrD
JHT10_RS20420	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JHT10_RS20425	COG3842	ATPase activity
JHT10_RS20435	COG1840	ABC-type Fe3 transport system, periplasmic component
JHT10_RS20440	COG0004	ammonium transporteR
JHT10_RS20450	COG3112	Uncharacterised protein family (UPF0231)
JHT10_RS20455	COG1049	propionate catabolic process, 2-methylcitrate cycle
JHT10_RS20460	COG1752	Esterase of the alpha-beta hydrolase superfamily
JHT10_RS20465	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JHT10_RS20470	COG1643	Atp-dependent helicase
JHT10_RS20475	COG1489	DNA binding
JHT10_RS20485	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JHT10_RS20495	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
JHT10_RS20500	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
JHT10_RS20505	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
JHT10_RS20510	COG1560	Kdo2-lipid A biosynthetic process
JHT10_RS20515	COG0842	Transport permease protein
JHT10_RS20520	COG1131	(ABC) transporter
JHT10_RS20525	COG0659	secondary active sulfate transmembrane transporter activity
JHT10_RS20530	COG0288	reversible hydration of carbon dioxide
JHT10_RS20545	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JHT10_RS20550	COG0508	dehydrogenase complex catalyzes the overall conversion of
JHT10_RS20555	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
JHT10_RS20560	COG2186	Transcriptional regulator
JHT10_RS20570	COG0157	Belongs to the NadC ModD family
JHT10_RS20575	COG4969	Belongs to the N-Me-Phe pilin family
JHT10_RS20580	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JHT10_RS20585	COG1459	type II secretion system
JHT10_RS20595	COG0237	dephospho-CoA kinase activity
JHT10_RS20600	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
JHT10_RS20605	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
JHT10_RS20610	COG0335	large ribosomal subunit rRNA binding
JHT10_RS20615	COG0336	Belongs to the RNA methyltransferase TrmD family
JHT10_RS20620	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
JHT10_RS20625	COG0228	four-way junction DNA binding
JHT10_RS20630	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
JHT10_RS20635	COG4137	Cytochrome C assembly protein
JHT10_RS20640	COG4536	flavin adenine dinucleotide binding
JHT10_RS20645	COG1854	S-ribosylhomocysteine lyase activity
JHT10_RS20655	COG2918	glutathione biosynthetic process
JHT10_RS20660	COG0612	Peptidase, M16
JHT10_RS20665	COG1238	metal cluster binding
JHT10_RS20675	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
JHT10_RS20680	COG0511	ligase activity, forming carbon-carbon bonds
JHT10_RS20680	COG5016	pyruvate
JHT10_RS20685	COG3630	sodium ion export across plasma membrane
JHT10_RS20735	COG0527	aspartate kinase activity
JHT10_RS20740	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JHT10_RS20745	COG2137	regulation of response to DNA damage stimulus
JHT10_RS20750	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
JHT10_RS20755	COG1546	Belongs to the CinA family
JHT10_RS20760	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
JHT10_RS20765	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JHT10_RS20775	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
JHT10_RS20780	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
JHT10_RS20785	COG0585	pseudouridine synthase activity
JHT10_RS20790	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
JHT10_RS20795	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
JHT10_RS20800	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
JHT10_RS20805	COG0148	phosphopyruvate hydratase activity
JHT10_RS20810	COG0504	CTP synthase activity
JHT10_RS20815	COG3956	TIGRFAM MazG family protein
JHT10_RS20820	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JHT10_RS20825	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JHT10_RS20835	COG0736	holo-[acyl-carrier-protein] synthase activity
JHT10_RS20840	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
JHT10_RS20845	COG1381	Involved in DNA repair and RecF pathway recombination
JHT10_RS20850	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
JHT10_RS20855	COG0571	ribonuclease III activity
JHT10_RS20865	COG0481	GTPase activity
JHT10_RS20870	COG3086	response to oxidative stress
JHT10_RS20880	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
JHT10_RS20885	COG1595	DNA-templated transcription, initiation
JHT10_RS20890	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
JHT10_RS20895	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
JHT10_RS20900	COG0354	folic acid binding
JHT10_RS20915	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JHT10_RS20920	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JHT10_RS20925	COG3079	Belongs to the UPF0149 family
JHT10_RS20930	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
JHT10_RS20940	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JHT10_RS20945	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
JHT10_RS20950	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JHT10_RS20960	COG0583	DNA-binding transcription factor activity
JHT10_RS20970	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
JHT10_RS20975	COG0668	transmembrane transport
JHT10_RS20980	COG0191	fructose-bisphosphate aldolase activity
JHT10_RS20985	COG0126	phosphoglycerate kinase activity
JHT10_RS20990	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
JHT10_RS20995	COG4771	TonB-dependent receptor
JHT10_RS21000	COG0583	DNA-binding transcription factor activity
JHT10_RS21005	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
JHT10_RS21010	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
JHT10_RS21020	COG3091	SprT-like family
JHT10_RS21025	COG2356	endonuclease I
JHT10_RS21030	COG1385	rRNA (uridine-N3-)-methyltransferase activity
JHT10_RS21035	COG0189	ligase activity
JHT10_RS21040	COG1678	Uncharacterized ACR, COG1678
JHT10_RS21045	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
JHT10_RS21060	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
JHT10_RS21065	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JHT10_RS21070	COG0762	integral membrane protein
JHT10_RS21075	COG1872	DUF167
JHT10_RS21085	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
JHT10_RS21090	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JHT10_RS21095	COG2066	Belongs to the glutaminase family
JHT10_RS21105	COG0220	tRNA (guanine-N7-)-methyltransferase activity
JHT10_RS21115	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
JHT10_RS21120	COG0741	lytic transglycosylase activity
JHT10_RS21190	COG1012	belongs to the aldehyde dehydrogenase family
JHT10_RS21235	COG0175	sulfate reduction
JHT10_RS21240	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JHT10_RS21245	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
JHT10_RS21265	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JHT10_RS21270	COG0735	belongs to the Fur family
JHT10_RS21280	COG0166	Belongs to the GPI family
JHT10_RS21285	COG0432	Pfam Uncharacterised protein family UPF0047
JHT10_RS21295	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JHT10_RS21310	COG0359	binds to the 23S rRNA
JHT10_RS21320	COG2965	DNA replication, synthesis of RNA primer
JHT10_RS21325	COG0360	Binds together with S18 to 16S ribosomal RNA
JHT10_RS21330	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
JHT10_RS21335	COG0338	D12 class N6 adenine-specific DNA methyltransferase
JHT10_RS21345	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
JHT10_RS21350	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
JHT10_RS21380	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
JHT10_RS21390	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
JHT10_RS21390	COG0678	peroxiredoxin activity
JHT10_RS21400	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
JHT10_RS21400	COG0165	Argininosuccinate lyase
JHT10_RS21405	COG0137	argininosuccinate synthase activity
JHT10_RS21410	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
JHT10_RS21415	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
JHT10_RS21420	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JHT10_RS21425	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
JHT10_RS21435	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
JHT10_RS21440	COG0527	aspartate kinase activity
JHT10_RS21440	COG0460	homoserine dehydrogenase
JHT10_RS21445	COG0626	cystathionine gamma-synthase activity
JHT10_RS21455	COG0281	malic enzyme
JHT10_RS21465	COG2906	2 iron, 2 sulfur cluster binding
JHT10_RS21470	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JHT10_RS21475	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JHT10_RS21480	COG0049	tRNA binding
JHT10_RS21495	COG2923	Belongs to the DsrF TusC family
JHT10_RS21500	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
JHT10_RS21505	COG2964	Protein conserved in bacteria
JHT10_RS21510	COG0545	Peptidyl-prolyl cis-trans isomerase
JHT10_RS21520	COG2900	Belongs to the SlyX family
JHT10_RS21525	COG1446	asparaginase
JHT10_RS21530	COG1047	Peptidyl-prolyl cis-trans
JHT10_RS21545	COG2249	NAD(P)H dehydrogenase (quinone) activity
JHT10_RS21550	COG0488	(ABC) transporter
JHT10_RS21560	COG0429	hydrolase of the alpha beta-hydrolase fold
JHT10_RS21565	COG3089	Belongs to the UPF0270 family
JHT10_RS21570	COG3954	Phosphoribulokinase
JHT10_RS21575	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JHT10_RS21585	COG1012	belongs to the aldehyde dehydrogenase family
JHT10_RS21595	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JHT10_RS21600	COG0512	Glutamine amidotransferase of anthranilate synthase
JHT10_RS21615	COG0180	Tryptophanyl-tRNA synthetase
JHT10_RS21620	COG0546	phosphoglycolate phosphatase activity
JHT10_RS21625	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JHT10_RS21630	COG0557	exoribonuclease II activity
JHT10_RS21635	COG1959	2 iron, 2 sulfur cluster binding
JHT10_RS21640	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JHT10_RS21640	COG1017	nitric oxide dioxygenase activity
JHT10_RS21645	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
JHT10_RS21650	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
JHT10_RS21655	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
JHT10_RS21660	COG0330	HflC and HflK could
JHT10_RS21665	COG0330	HflC and HflK could
JHT10_RS21670	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JHT10_RS21680	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
JHT10_RS21685	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
JHT10_RS21695	COG0802	atpase or kinase
JHT10_RS21700	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
JHT10_RS21770	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
JHT10_RS21775	COG1162	GTPase activity
JHT10_RS21780	COG0688	phosphatidylethanolamine metabolic process
JHT10_RS21785	COG0471	metal ion transport
JHT10_RS21800	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
JHT10_RS21805	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JHT10_RS21810	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
JHT10_RS21815	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
JHT10_RS21820	COG1045	serine acetyltransferase
JHT10_RS21825	COG4942	peptidase
JHT10_RS21845	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
JHT10_RS21850	COG1053	succinate dehydrogenase
JHT10_RS21855	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
JHT10_RS21860	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
JHT10_RS21865	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
JHT10_RS21875	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JHT10_RS21880	COG1509	lysine 2,3-aminomutase activity
JHT10_RS21885	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JHT10_RS21900	COG0459	protein refolding
JHT10_RS21910	COG0534	Mate efflux family protein
JHT10_RS21915	COG0205	6-phosphofructokinase activity
JHT10_RS21925	COG3678	ATP-independent chaperone mediated protein folding
JHT10_RS21930	COG0745	RESPONSE REGULATOR receiver
JHT10_RS21935	COG2205	protein histidine kinase activity
JHT10_RS21945	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
JHT10_RS21950	COG3030	protein affecting phage T7 exclusion by the F plasmid
JHT10_RS21955	COG1027	Aspartate ammonia-lyase
JHT10_RS21960	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
JHT10_RS21965	COG4232	protein-disulfide reductase activity
JHT10_RS21975	COG3263	regulation of cellular component size
JHT10_RS21985	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JHT10_RS22005	COG0784	Response regulator, receiver
JHT10_RS22005	COG2205	protein histidine kinase activity
JHT10_RS22005	COG2198	Histidine kinase
JHT10_RS22010	COG2814	Major facilitator Superfamily
JHT10_RS22025	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JHT10_RS22030	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
JHT10_RS22035	COG0511	ligase activity, forming carbon-carbon bonds
JHT10_RS22040	COG0439	Biotin carboxylase
JHT10_RS22045	COG2264	protein methyltransferase activity
JHT10_RS22050	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JHT10_RS22055	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
JHT10_RS22060	COG2814	Major facilitator Superfamily
JHT10_RS22065	COG0488	(ABC) transporter
JHT10_RS22070	COG3706	GGDEF domain
JHT10_RS22110	COG3437	response regulator, receiver
JHT10_RS22120	COG3394	polysaccharide catabolic process
JHT10_RS22125	COG1486	melibiose metabolic process
JHT10_RS22130	COG1447	Phosphotransferase system cellobiose-specific component IIA
JHT10_RS22135	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JHT10_RS22140	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JHT10_RS22145	COG0726	polysaccharide deacetylase
JHT10_RS22245	COG1028	Short-chain dehydrogenase reductase Sdr
JHT10_RS22260	COG0795	lipopolysaccharide-transporting ATPase activity
JHT10_RS22265	COG0795	lipopolysaccharide-transporting ATPase activity
JHT10_RS22270	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
JHT10_RS22275	COG2927	DNA polymerase III (CHI subunit)
JHT10_RS22280	COG0525	valine-tRNA ligase activity
JHT10_RS22305	COG2235	arginine
JHT10_RS22310	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
JHT10_RS22320	COG0540	Belongs to the ATCase OTCase family
JHT10_RS22325	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
JHT10_RS22330	COG0251	oxidation-reduction process
JHT10_RS22335	COG0204	Acyl-transferase
JHT10_RS22340	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JHT10_RS22345	COG5007	Belongs to the BolA IbaG family
JHT10_RS22355	COG2854	intermembrane phospholipid transfer
JHT10_RS22360	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
JHT10_RS22365	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JHT10_RS22370	COG1127	ABC transporter
JHT10_RS22380	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
JHT10_RS22380	COG0517	IMP dehydrogenase activity
JHT10_RS22390	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
JHT10_RS22395	COG1137	ATPase activity
JHT10_RS22405	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
JHT10_RS22410	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JHT10_RS22415	COG1660	Displays ATPase and GTPase activities
JHT10_RS22420	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
JHT10_RS22425	COG2239	Acts as a magnesium transporter
JHT10_RS22430	COG0312	modulator of DNA gyrase
JHT10_RS22435	COG3028	Belongs to the UPF0307 family
JHT10_RS22440	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JHT10_RS22445	COG0564	pseudouridine synthase activity
JHT10_RS22455	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JHT10_RS22460	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
JHT10_RS22465	COG0312	modulator of DNA gyrase
JHT10_RS22470	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JHT10_RS22475	COG3164	Protein of unknown function
JHT10_RS22485	COG0424	maF-like protein
JHT10_RS22490	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
JHT10_RS22495	COG1792	Involved in formation and maintenance of cell shape
JHT10_RS22500	COG1077	Cell shape determining protein MreB Mrl
JHT10_RS22545	COG1459	type II secretion system
JHT10_RS22550	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JHT10_RS22560	COG3409	Peptidoglycan-binding domain 1 protein
JHT10_RS22560	COG3267	Type II secretory pathway component ExeA
JHT10_RS22585	COG2200	EAL domain
JHT10_RS22585	COG2199	diguanylate cyclase activity
JHT10_RS22590	COG0629	single-stranded DNA binding
JHT10_RS22605	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
JHT10_RS22615	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
JHT10_RS22620	COG0527	aspartate kinase activity
JHT10_RS22625	COG1410	methionine synthase
JHT10_RS22625	COG0646	methionine synthase
JHT10_RS22690	COG1982	Orn Lys Arg decarboxylase major
JHT10_RS22695	COG0531	amino acid
JHT10_RS22705	COG3710	Transcriptional regulator
JHT10_RS22710	COG0789	Transcriptional regulator
JHT10_RS22715	COG0138	bifunctional purine biosynthesis protein purh
JHT10_RS22720	COG0151	Belongs to the GarS family
JHT10_RS22735	COG1253	flavin adenine dinucleotide binding
JHT10_RS22745	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JHT10_RS22750	COG1573	uracil-dna glycosylase
JHT10_RS22755	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
JHT10_RS22770	COG2816	NAD+ diphosphatase activity
JHT10_RS22775	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
JHT10_RS22780	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JHT10_RS22785	COG0085	RNA polymerase activity
JHT10_RS22790	COG0222	ribosome binding
JHT10_RS22795	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
JHT10_RS22800	COG0081	regulation of translation
JHT10_RS22805	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
JHT10_RS22810	COG0250	Participates in transcription elongation, termination and antitermination
JHT10_RS22815	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
JHT10_RS22820	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JHT10_RS22855	COG0812	UDP-N-acetylmuramate dehydrogenase activity
JHT10_RS22865	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JHT10_RS22895	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
JHT10_RS22905	COG4206	TonB-dependent receptor
JHT10_RS22925	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JHT10_RS22930	COG0534	Mate efflux family protein
JHT10_RS22935	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
JHT10_RS22940	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
JHT10_RS22945	COG2937	Belongs to the GPAT DAPAT family
JHT10_RS22950	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
JHT10_RS22955	COG3161	chorismate lyase activity
JHT10_RS22960	COG1580	Controls the rotational direction of flagella during chemotaxis
JHT10_RS22965	COG0705	Rhomboid family
JHT10_RS22970	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JHT10_RS22980	COG2177	Part of the ABC transporter FtsEX involved in
JHT10_RS22985	COG2884	Cell division ATP-binding protein ftsE
JHT10_RS22990	COG0552	protein localization to endoplasmic reticulum
JHT10_RS22995	COG0742	ribosomal rna small subunit methyltransferase
JHT10_RS23005	COG2095	MarC family integral membrane protein
JHT10_RS23055	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
JHT10_RS23060	COG0640	Transcriptional regulator
JHT10_RS23065	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
JHT10_RS23070	COG1280	lysine exporter protein (LysE YggA)
JHT10_RS23075	COG2267	carboxylic ester hydrolase activity
JHT10_RS23080	COG0561	phosphatase activity
JHT10_RS23095	COG3148	PFAM DTW domain containing protein
JHT10_RS23100	COG2199	diguanylate cyclase activity
JHT10_RS23100	COG2200	EAL domain
JHT10_RS23100	COG3287	FIST C domain
JHT10_RS23105	COG1011	Hydrolase
JHT10_RS23110	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
JHT10_RS23120	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
JHT10_RS23125	COG0019	diaminopimelate decarboxylase activity
JHT10_RS23135	COG1965	Belongs to the frataxin family
JHT10_RS23140	COG3072	Adenylate cyclase
JHT10_RS23145	COG0181	hydroxymethylbilane synthase activity
JHT10_RS23150	COG1587	Uroporphyrinogen-III synthase
JHT10_RS23155	COG2959	enzyme of heme biosynthesis
JHT10_RS23160	COG3071	HemY protein
JHT10_RS23230	COG0633	Ferredoxin
JHT10_RS23235	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
JHT10_RS23250	COG3118	belongs to the thioredoxin family
JHT10_RS23255	COG0513	Belongs to the DEAD box helicase family
JHT10_RS23260	COG0248	Ppx GppA phosphatase
JHT10_RS23265	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
JHT10_RS23275	COG0514	ATP-dependent DNA helicase (RecQ)
JHT10_RS23280	COG2962	Rard protein
JHT10_RS23290	COG1280	lysine exporter protein (LysE YggA)
JHT10_RS23295	COG0405	Gamma-glutamyltransferase
JHT10_RS23300	COG0210	DNA helicase
JHT10_RS23310	COG3220	belongs to the UPF0276 family
JHT10_RS23340	COG0006	proline dipeptidase activity
JHT10_RS23340	COG0006	proline dipeptidase activity
JHT10_RS23350	COG2022	thiamine diphosphate biosynthetic process
JHT10_RS23355	COG2104	thiamine diphosphate biosynthetic process
JHT10_RS23360	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JHT10_RS23370	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
JHT10_RS23375	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JHT10_RS23420	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
JHT10_RS23430	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JHT10_RS23435	COG0408	coproporphyrinogen oxidase activity
JHT10_RS23440	COG0009	L-threonylcarbamoyladenylate synthase
JHT10_RS23445	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
JHT10_RS23450	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
JHT10_RS23455	COG0551	DNA topoisomerase type I activity
JHT10_RS23460	COG2922	Belongs to the Smg family
JHT10_RS23465	COG0758	DNA mediated transformation
JHT10_RS23475	COG0242	peptide deformylase activity
JHT10_RS23480	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
JHT10_RS23485	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JHT10_RS23485	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JHT10_RS23490	COG0569	domain protein
JHT10_RS23495	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JHT10_RS23505	COG1272	protein, Hemolysin III
JHT10_RS23510	COG4326	sporulation control protein
JHT10_RS23515	COG3084	Protein conserved in bacteria
JHT10_RS23525	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
JHT10_RS23530	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JHT10_RS23535	COG0204	Acyl-transferase
JHT10_RS23545	COG0606	chelatase, subunit chli
JHT10_RS23555	COG3978	acetolactate synthase activity
JHT10_RS23560	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JHT10_RS23565	COG0129	dihydroxy-acid dehydratase activity
JHT10_RS23575	COG0583	DNA-binding transcription factor activity
JHT10_RS23580	COG2814	Major facilitator Superfamily
JHT10_RS23585	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JHT10_RS23590	COG0765	amino acid transport
JHT10_RS23595	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
JHT10_RS23600	COG0355	proton-transporting ATP synthase activity, rotational mechanism
JHT10_RS23605	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
JHT10_RS23610	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
JHT10_RS23615	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
JHT10_RS23620	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JHT10_RS23635	COG0356	it plays a direct role in the translocation of protons across the membrane
JHT10_RS23640	COG3312	ion transport
JHT10_RS23645	COG1475	DNA binding
JHT10_RS23650	COG1192	Involved in chromosome partitioning
JHT10_RS23655	COG0357	Ribosomal RNA small subunit methyltransferase G
JHT10_RS23660	COG0445	tRNA wobble uridine modification
JHT10_RS23665	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
JHT10_RS23670	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
JHT10_RS23675	COG0706	membrane insertase activity
JHT10_RS23685	COG0594	ribonuclease P activity
JHT10_RS23695	COG1126	abc transporter atp-binding protein
JHT10_RS23730	COG4932	domain protein
JHT10_RS23730	COG5492	domain, Protein
JHT10_RS23930	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JHT10_RS24040	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JHT10_RS24070	COG2948	multi-organism process
JHT10_RS24090	COG3701	Conjugal transfer protein
JHT10_RS24100	COG4962	Type ii secretion system protein e
JHT10_RS24110	COG3451	type IV secretory pathway VirB4
JHT10_RS24115	COG5268	conjugation