locus-tag	class	description
LDO37_RS00010	COG0592	DNA-directed DNA polymerase activity
LDO37_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LDO37_RS00020	COG0187	DNA topoisomerase II activity
LDO37_RS00025	COG0071	Belongs to the small heat shock protein (HSP20) family
LDO37_RS00030	COG3977	Valine--pyruvate aminotransferase
LDO37_RS00045	COG0751	glycine-tRNA ligase activity
LDO37_RS00055	COG2119	membrane
LDO37_RS00080	COG0604	alcohol dehydrogenase
LDO37_RS00085	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
LDO37_RS00090	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
LDO37_RS00095	COG3454	Phosphonate metabolism
LDO37_RS00100	COG4778	phosphonate C-P lyase system protein PhnL
LDO37_RS00105	COG4107	phosphonate C-P lyase system protein PhnK
LDO37_RS00110	COG3627	carbon phosphorus lyase activity
LDO37_RS00115	COG3626	phosphonate metabolism
LDO37_RS00120	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
LDO37_RS00125	COG3624	Phosphonate C-P lyase system protein PhnG
LDO37_RS00130	COG2188	Transcriptional regulator
LDO37_RS00135	COG3639	organic phosphonate transmembrane transporter activity
LDO37_RS00140	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
LDO37_RS00165	COG1739	Uncharacterized protein family UPF0029
LDO37_RS00170	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LDO37_RS00175	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
LDO37_RS00220	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LDO37_RS00225	COG0583	DNA-binding transcription factor activity
LDO37_RS00230	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
LDO37_RS00235	COG2960	long-chain fatty acid transporting porin activity
LDO37_RS00240	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LDO37_RS00245	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LDO37_RS00250	COG1309	transcriptional regulator
LDO37_RS00290	COG4172	Belongs to the ABC transporter superfamily
LDO37_RS00295	COG4166	transmembrane transport
LDO37_RS00300	COG0601	transmembrane transport
LDO37_RS00305	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LDO37_RS00335	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LDO37_RS00335	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LDO37_RS00360	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LDO37_RS00370	COG2197	response regulator
LDO37_RS00380	COG4989	oxidoreductase activity
LDO37_RS00400	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LDO37_RS00405	COG5001	Diguanylate cyclase
LDO37_RS00405	COG3300	MHYT domain
LDO37_RS00410	COG2204	response regulator
LDO37_RS00415	COG3852	Histidine kinase
LDO37_RS00425	COG0174	glutamine synthetase
LDO37_RS00430	COG1217	gtp-binding protein TYPA
LDO37_RS00520	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LDO37_RS00525	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
LDO37_RS00530	COG0339	signal peptide processing
LDO37_RS00535	COG1522	sequence-specific DNA binding
LDO37_RS00540	COG5001	Diguanylate cyclase
LDO37_RS00540	COG5002	protein histidine kinase activity
LDO37_RS00555	COG0589	response to stress
LDO37_RS00560	COG1528	Iron-storage protein
LDO37_RS00570	COG2081	HI0933 family
LDO37_RS00575	COG0667	Aldo Keto reductase
LDO37_RS00620	COG4964	Belongs to the GSP D family
LDO37_RS00685	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LDO37_RS00695	COG3085	chromosome segregation
LDO37_RS00705	COG1322	Protein conserved in bacteria
LDO37_RS00710	COG2226	methyltransferase
LDO37_RS00715	COG3165	ubiquinone biosynthetic process from chorismate
LDO37_RS00720	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LDO37_RS00725	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LDO37_RS00730	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LDO37_RS00735	COG0805	protein transport
LDO37_RS00740	COG0084	hydrolase, TatD family'
LDO37_RS00755	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LDO37_RS00755	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LDO37_RS00785	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LDO37_RS00795	COG1295	ribonuclease BN
LDO37_RS00805	COG0456	acetyltransferase
LDO37_RS00815	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
LDO37_RS00825	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
LDO37_RS00830	COG3031	protein transport across the cell outer membrane
LDO37_RS00840	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LDO37_RS00845	COG1459	type II secretion system
LDO37_RS00850	COG2165	general secretion pathway protein
LDO37_RS00855	COG2165	general secretion pathway protein
LDO37_RS00860	COG2165	general secretion pathway protein
LDO37_RS00865	COG4795	General secretion pathway protein
LDO37_RS00870	COG3156	type II secretion system protein K
LDO37_RS00875	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
LDO37_RS00880	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
LDO37_RS00890	COG0494	nUDIX hydrolase
LDO37_RS00895	COG1218	3'(2'),5'-bisphosphate nucleotidase
LDO37_RS00925	COG2937	Belongs to the GPAT DAPAT family
LDO37_RS00930	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LDO37_RS00935	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
LDO37_RS00940	COG0534	Mate efflux family protein
LDO37_RS00945	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LDO37_RS00960	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LDO37_RS00965	COG4206	TonB-dependent receptor
LDO37_RS00980	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
LDO37_RS01040	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LDO37_RS01050	COG0812	UDP-N-acetylmuramate dehydrogenase activity
LDO37_RS01060	COG1072	(Pantothenic acid kinase))
LDO37_RS01085	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LDO37_RS01090	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LDO37_RS01095	COG0250	Participates in transcription elongation, termination and antitermination
LDO37_RS01110	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LDO37_RS01125	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LDO37_RS01130	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
LDO37_RS01135	COG2816	NAD+ diphosphatase activity
LDO37_RS01145	COG1573	uracil-dna glycosylase
LDO37_RS01150	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LDO37_RS01155	COG3068	Protein conserved in bacteria
LDO37_RS01160	COG1253	flavin adenine dinucleotide binding
LDO37_RS01175	COG0151	Belongs to the GarS family
LDO37_RS01180	COG0138	bifunctional purine biosynthesis protein purh
LDO37_RS01195	COG0840	transmembrane signaling receptor activity
LDO37_RS01200	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
LDO37_RS01205	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LDO37_RS01210	COG2264	protein methyltransferase activity
LDO37_RS01215	COG0439	Biotin carboxylase
LDO37_RS01220	COG0511	ligase activity, forming carbon-carbon bonds
LDO37_RS01225	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
LDO37_RS01235	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LDO37_RS01250	COG2814	Major facilitator Superfamily
LDO37_RS01255	COG2205	protein histidine kinase activity
LDO37_RS01255	COG2198	Histidine kinase
LDO37_RS01255	COG0784	Response regulator, receiver
LDO37_RS01285	COG3842	ATPase activity
LDO37_RS01295	COG1840	ABC-type Fe3 transport system, periplasmic component
LDO37_RS01300	COG2204	response regulator
LDO37_RS01305	COG4191	Histidine kinase
LDO37_RS01315	COG4232	protein-disulfide reductase activity
LDO37_RS01320	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
LDO37_RS01325	COG1027	Aspartate ammonia-lyase
LDO37_RS01335	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LDO37_RS01345	COG2205	protein histidine kinase activity
LDO37_RS01350	COG0745	RESPONSE REGULATOR receiver
LDO37_RS01370	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LDO37_RS01380	COG0534	Mate efflux family protein
LDO37_RS01390	COG0459	protein refolding
LDO37_RS01400	COG1285	pathogenesis
LDO37_RS01410	COG3778	Protein conserved in bacteria
LDO37_RS01445	COG4518	Phage tail assembly chaperone proteins, E, or 41 or 14
LDO37_RS01455	COG4386	tail sheath protein
LDO37_RS01475	COG4387	Mu-like prophage protein GP36
LDO37_RS01485	COG4397	Mu-like prophage major head subunit gpT
LDO37_RS01520	COG4383	Mu-like prophage protein gp29
LDO37_RS01525	COG4373	Mu-like prophage FluMu protein gp28
LDO37_RS01535	COG0640	Transcriptional regulator
LDO37_RS01630	COG2842	Transposition protein
LDO37_RS01635	COG2801	Transposase and inactivated derivatives
LDO37_RS01640	COG3423	Transcriptional regulator
LDO37_RS01655	COG1509	lysine 2,3-aminomutase activity
LDO37_RS01660	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LDO37_RS01695	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
LDO37_RS01700	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LDO37_RS01705	COG1053	succinate dehydrogenase
LDO37_RS01710	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
LDO37_RS01720	COG0584	glycerophosphoryl diester phosphodiesterase
LDO37_RS01725	COG0471	metal ion transport
LDO37_RS01730	COG0688	phosphatidylethanolamine metabolic process
LDO37_RS01735	COG1162	GTPase activity
LDO37_RS01740	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
LDO37_RS01785	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LDO37_RS01790	COG0802	atpase or kinase
LDO37_RS01795	COG0860	N-Acetylmuramoyl-L-alanine amidase
LDO37_RS01800	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LDO37_RS01805	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LDO37_RS01815	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LDO37_RS01820	COG0330	HflC and HflK could
LDO37_RS01825	COG0330	HflC and HflK could
LDO37_RS01830	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
LDO37_RS01835	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LDO37_RS01840	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
LDO37_RS01845	COG1017	nitric oxide dioxygenase activity
LDO37_RS01845	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LDO37_RS01855	COG3083	sulfuric ester hydrolase activity
LDO37_RS01860	COG0557	exoribonuclease II activity
LDO37_RS01865	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LDO37_RS01875	COG3954	Phosphoribulokinase
LDO37_RS01885	COG0429	hydrolase of the alpha beta-hydrolase fold
LDO37_RS01890	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LDO37_RS01910	COG0488	(ABC) transporter
LDO37_RS01930	COG1047	Peptidyl-prolyl cis-trans
LDO37_RS01935	COG1446	asparaginase
LDO37_RS01940	COG2900	Belongs to the SlyX family
LDO37_RS01950	COG0545	Peptidyl-prolyl cis-trans isomerase
LDO37_RS01955	COG2964	Protein conserved in bacteria
LDO37_RS01960	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
LDO37_RS01965	COG2923	Belongs to the DsrF TusC family
LDO37_RS01985	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LDO37_RS01990	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LDO37_RS02005	COG0051	transcription antitermination factor activity, RNA binding
LDO37_RS02010	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LDO37_RS02015	COG0088	Forms part of the polypeptide exit tunnel
LDO37_RS02025	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LDO37_RS02030	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LDO37_RS02035	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LDO37_RS02045	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LDO37_RS02055	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LDO37_RS02065	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LDO37_RS02070	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LDO37_RS02075	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LDO37_RS02080	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LDO37_RS02100	COG1841	ribosomal large subunit assembly
LDO37_RS02105	COG0200	Binds to the 23S rRNA
LDO37_RS02110	COG0201	protein transport
LDO37_RS02115	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LDO37_RS02120	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LDO37_RS02125	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LDO37_RS02135	COG0202	RNA polymerase activity
LDO37_RS02140	COG0203	ribosomal protein L17
LDO37_RS02145	COG2873	o-acetylhomoserine
LDO37_RS02155	COG0545	Peptidyl-prolyl cis-trans isomerase
LDO37_RS02160	COG3061	Opacity-associated protein A
LDO37_RS02160	COG3266	domain, Protein
LDO37_RS02195	COG0697	spore germination
LDO37_RS02200	COG2153	protein acetylation
LDO37_RS02210	COG0737	Belongs to the 5'-nucleotidase family
LDO37_RS02215	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LDO37_RS02215	COG1648	precorrin-2 dehydrogenase activity
LDO37_RS02220	COG0175	sulfate reduction
LDO37_RS02225	COG2895	sulfate adenylyltransferase (ATP) activity
LDO37_RS02230	COG3273	potassium ion transport
LDO37_RS02230	COG0471	metal ion transport
LDO37_RS02235	COG0529	Catalyzes the synthesis of activated sulfate
LDO37_RS02255	COG1136	(ABC) transporter
LDO37_RS02270	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
LDO37_RS02275	COG0540	Belongs to the ATCase OTCase family
LDO37_RS02280	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LDO37_RS02285	COG2235	arginine
LDO37_RS02320	COG4269	membrane
LDO37_RS02325	COG0501	Belongs to the peptidase M48B family
LDO37_RS02330	COG0251	oxidation-reduction process
LDO37_RS02340	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
LDO37_RS02350	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
LDO37_RS02360	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LDO37_RS02365	COG3284	Transcriptional regulator
LDO37_RS02580	COG0729	surface antigen
LDO37_RS02585	COG2911	Protein conserved in bacteria
LDO37_RS02590	COG2105	PFAM AIG2 family protein
LDO37_RS02595	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
LDO37_RS02600	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
LDO37_RS02605	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LDO37_RS02610	COG0163	prenyltransferase activity
LDO37_RS02620	COG1178	ABC-type Fe3 transport system permease component
LDO37_RS02625	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
LDO37_RS02635	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LDO37_RS02640	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LDO37_RS02645	COG1447	Phosphotransferase system cellobiose-specific component IIA
LDO37_RS02650	COG1486	melibiose metabolic process
LDO37_RS02660	COG1609	Transcriptional regulator
LDO37_RS02670	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
LDO37_RS02745	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
LDO37_RS02755	COG0646	methionine synthase
LDO37_RS02755	COG1410	methionine synthase
LDO37_RS02760	COG0527	aspartate kinase activity
LDO37_RS02765	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
LDO37_RS02775	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LDO37_RS02790	COG0629	single-stranded DNA binding
LDO37_RS02795	COG2200	EAL domain
LDO37_RS02795	COG2199	diguanylate cyclase activity
LDO37_RS02820	COG3409	Peptidoglycan-binding domain 1 protein
LDO37_RS02820	COG3267	Type II secretory pathway component ExeA
LDO37_RS02830	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LDO37_RS02835	COG1459	type II secretion system
LDO37_RS02845	COG2165	general secretion pathway protein
LDO37_RS02850	COG2165	general secretion pathway protein
LDO37_RS02880	COG1077	Cell shape determining protein MreB Mrl
LDO37_RS02885	COG1792	Involved in formation and maintenance of cell shape
LDO37_RS02890	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
LDO37_RS02895	COG0424	maF-like protein
LDO37_RS02905	COG3164	Protein of unknown function
LDO37_RS02910	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LDO37_RS02915	COG0312	modulator of DNA gyrase
LDO37_RS02920	COG3028	Belongs to the UPF0307 family
LDO37_RS02925	COG0312	modulator of DNA gyrase
LDO37_RS02970	COG0758	DNA mediated transformation
LDO37_RS02985	COG0582	viral genome integration into host DNA
LDO37_RS03030	COG0795	lipopolysaccharide-transporting ATPase activity
LDO37_RS03035	COG0795	lipopolysaccharide-transporting ATPase activity
LDO37_RS03045	COG2927	DNA polymerase III (CHI subunit)
LDO37_RS03050	COG0525	valine-tRNA ligase activity
LDO37_RS03055	COG0204	Acyl-transferase
LDO37_RS03065	COG5007	Belongs to the BolA IbaG family
LDO37_RS03075	COG2854	intermembrane phospholipid transfer
LDO37_RS03080	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LDO37_RS03085	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LDO37_RS03090	COG1127	ABC transporter
LDO37_RS03100	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
LDO37_RS03100	COG0517	IMP dehydrogenase activity
LDO37_RS03105	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
LDO37_RS03120	COG1137	ATPase activity
LDO37_RS03130	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LDO37_RS03135	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LDO37_RS03140	COG1660	Displays ATPase and GTPase activities
LDO37_RS03145	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LDO37_RS03150	COG2239	Acts as a magnesium transporter
LDO37_RS03170	COG5002	protein histidine kinase activity
LDO37_RS03175	COG0745	RESPONSE REGULATOR receiver
LDO37_RS03185	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
LDO37_RS03190	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LDO37_RS03195	COG0564	pseudouridine synthase activity
LDO37_RS03200	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LDO37_RS03215	COG2358	TRAP transporter, solute receptor (TAXI family
LDO37_RS03220	COG1438	arginine binding
LDO37_RS03230	COG0142	geranyltranstransferase activity
LDO37_RS03235	COG0261	This protein binds to 23S rRNA in the presence of protein L20
LDO37_RS03245	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LDO37_RS03250	COG3610	response to peptide
LDO37_RS03255	COG3610	response to peptide
LDO37_RS03270	COG2967	ApaG domain
LDO37_RS03280	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
LDO37_RS03290	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
LDO37_RS03310	COG0066	3-isopropylmalate dehydratase activity
LDO37_RS03315	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LDO37_RS03320	COG0473	3-isopropylmalate dehydrogenase activity
LDO37_RS03325	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LDO37_RS03330	COG1309	transcriptional regulator
LDO37_RS03350	COG0671	phosphoesterase, PA-phosphatase related
LDO37_RS03360	COG0583	DNA-binding transcription factor activity
LDO37_RS03365	COG1022	Amp-dependent synthetase and ligase
LDO37_RS03375	COG2963	transposase activity
LDO37_RS03380	COG0028	Belongs to the TPP enzyme family
LDO37_RS03390	COG3447	MASE1 domain protein
LDO37_RS03390	COG5001	Diguanylate cyclase
LDO37_RS03390	COG5002	protein histidine kinase activity
LDO37_RS03400	COG0469	pyruvate kinase activity
LDO37_RS03405	COG1349	DNA-binding transcription factor activity
LDO37_RS03410	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LDO37_RS03420	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
LDO37_RS03445	COG0840	transmembrane signaling receptor activity
LDO37_RS03470	COG0358	DNA primase activity
LDO37_RS03475	COG1610	YqeY-like protein
LDO37_RS03480	COG0828	Belongs to the bacterial ribosomal protein bS21 family
LDO37_RS03485	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LDO37_RS03490	COG0596	Alpha beta hydrolase
LDO37_RS03495	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
LDO37_RS03500	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LDO37_RS03505	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LDO37_RS03515	COG0288	reversible hydration of carbon dioxide
LDO37_RS03520	COG0659	secondary active sulfate transmembrane transporter activity
LDO37_RS03525	COG1131	(ABC) transporter
LDO37_RS03530	COG0842	Transport permease protein
LDO37_RS03540	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
LDO37_RS03545	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LDO37_RS03555	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LDO37_RS03560	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LDO37_RS03570	COG1643	Atp-dependent helicase
LDO37_RS03575	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LDO37_RS03580	COG1752	Esterase of the alpha-beta hydrolase superfamily
LDO37_RS03585	COG1049	propionate catabolic process, 2-methylcitrate cycle
LDO37_RS03600	COG0004	ammonium transporteR
LDO37_RS03605	COG1840	ABC-type Fe3 transport system, periplasmic component
LDO37_RS03615	COG3842	ATPase activity
LDO37_RS03620	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LDO37_RS03635	COG2971	BadF BadG BcrA BcrD
LDO37_RS03645	COG4608	Belongs to the ABC transporter superfamily
LDO37_RS03650	COG0444	Belongs to the ABC transporter superfamily
LDO37_RS03655	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LDO37_RS03665	COG0747	negative chemotaxis
LDO37_RS03670	COG0784	Response regulator, receiver
LDO37_RS03670	COG2205	protein histidine kinase activity
LDO37_RS03675	COG2813	Specifically methylates the guanine in position
LDO37_RS03680	COG0628	permease
LDO37_RS03705	COG0739	heme binding
LDO37_RS03710	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LDO37_RS03725	COG2027	D-alanyl-D-alanine carboxypeptidase
LDO37_RS03730	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
LDO37_RS03735	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LDO37_RS03740	COG1534	Rna-binding protein
LDO37_RS03745	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
LDO37_RS03750	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LDO37_RS03755	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LDO37_RS03765	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LDO37_RS03780	COG0779	Required for maturation of 30S ribosomal subunits
LDO37_RS03785	COG0195	Participates in both transcription termination and antitermination
LDO37_RS03790	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LDO37_RS03795	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LDO37_RS03800	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LDO37_RS03805	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LDO37_RS03810	COG1185	polyribonucleotide nucleotidyltransferase activity
LDO37_RS03820	COG0826	peptidase U32
LDO37_RS03825	COG0826	peptidase U32
LDO37_RS03835	COG3154	lipid carrier protein
LDO37_RS03840	COG3153	acetyltransferase
LDO37_RS03895	COG1737	Transcriptional regulator
LDO37_RS03900	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LDO37_RS03905	COG0022	dehydrogenase e1 component
LDO37_RS03910	COG0508	dehydrogenase complex catalyzes the overall conversion of
LDO37_RS03920	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LDO37_RS03930	COG1129	ABC transporter
LDO37_RS03945	COG1172	Belongs to the binding-protein-dependent transport system permease family
LDO37_RS03950	COG1028	Short-chain dehydrogenase reductase Sdr
LDO37_RS03960	COG1063	alcohol dehydrogenase
LDO37_RS03970	COG0084	hydrolase, TatD family'
LDO37_RS03975	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LDO37_RS03985	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
LDO37_RS03990	COG0813	purine-nucleoside phosphorylase activity
LDO37_RS04000	COG0560	Phosphoserine phosphatase
LDO37_RS04010	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LDO37_RS04040	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LDO37_RS04055	COG0583	DNA-binding transcription factor activity
LDO37_RS04065	COG0583	DNA-binding transcription factor activity
LDO37_RS04075	COG1022	Amp-dependent synthetase and ligase
LDO37_RS04090	COG3437	response regulator, receiver
LDO37_RS04090	COG0784	Response regulator, receiver
LDO37_RS04095	COG2059	Chromate
LDO37_RS04140	COG1929	Belongs to the glycerate kinase type-1 family
LDO37_RS04145	COG2610	gluconate transmembrane transporter activity
LDO37_RS04150	COG3835	regulator
LDO37_RS04180	COG2258	MOSC domain
LDO37_RS04200	COG2171	N-acyltransferase activity
LDO37_RS04205	COG3141	response to X-ray
LDO37_RS04210	COG0583	DNA-binding transcription factor activity
LDO37_RS04225	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
LDO37_RS04230	COG1074	ATP-dependent DNA helicase activity
LDO37_RS04235	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LDO37_RS04255	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
LDO37_RS04260	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
LDO37_RS04265	COG2166	iron-sulfur cluster assembly
LDO37_RS04275	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LDO37_RS04280	COG0693	protein deglycase activity
LDO37_RS04285	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LDO37_RS04300	COG1595	DNA-templated transcription, initiation
LDO37_RS04310	COG2211	Major facilitator Superfamily
LDO37_RS04315	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LDO37_RS04325	COG2813	Specifically methylates the guanine in position
LDO37_RS04330	COG0271	Belongs to the BolA IbaG family
LDO37_RS04335	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
LDO37_RS04345	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
LDO37_RS04350	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
LDO37_RS04355	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
LDO37_RS04360	COG2871	sodium ion transport
LDO37_RS04365	COG1477	protein flavinylation
LDO37_RS04385	COG1360	Flagellar Motor Protein
LDO37_RS04410	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LDO37_RS04430	COG3325	Belongs to the glycosyl hydrolase 18 family
LDO37_RS04430	COG3469	chitinase activity
LDO37_RS04435	COG0733	neurotransmitter:sodium symporter activity
LDO37_RS04460	COG1720	tRNA m6t6A37 methyltransferase activity
LDO37_RS04465	COG0254	rRNA binding
LDO37_RS04475	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
LDO37_RS04485	COG2608	mercury ion transmembrane transporter activity
LDO37_RS04485	COG2217	Heavy metal translocating P-type atpase
LDO37_RS04505	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
LDO37_RS04555	COG0835	chemotaxis
LDO37_RS04555	COG0784	Response regulator, receiver
LDO37_RS04560	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
LDO37_RS04565	COG1815	bacterial-type flagellum-dependent cell motility
LDO37_RS04570	COG1558	bacterial-type flagellum-dependent cell motility
LDO37_RS04580	COG1749	Flagellar hook protein flgE
LDO37_RS04585	COG4786	Flagellar basal body rod
LDO37_RS04600	COG1706	bacterial-type flagellum-dependent cell motility
LDO37_RS04605	COG1705	Flagellar rod assembly protein muramidase FlgJ
LDO37_RS04605	COG3951	Flagellar rod assembly protein muramidase FlgJ
LDO37_RS04615	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LDO37_RS04625	COG2190	(PTS) system
LDO37_RS04635	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LDO37_RS04645	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
LDO37_RS04665	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
LDO37_RS04670	COG0789	Transcriptional regulator
LDO37_RS04680	COG0330	HflC and HflK could
LDO37_RS04685	COG3118	belongs to the thioredoxin family
LDO37_RS04690	COG0300	oxidoreductase activity
LDO37_RS04695	COG1090	epimerase
LDO37_RS04720	COG0622	Phosphoesterase
LDO37_RS04740	COG3710	Transcriptional regulator
LDO37_RS04745	COG0326	Molecular chaperone. Has ATPase activity
LDO37_RS04755	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
LDO37_RS04760	COG0250	Participates in transcription elongation, termination and antitermination
LDO37_RS04765	COG0367	asparagine synthase
LDO37_RS04770	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LDO37_RS04770	COG4651	solute:proton antiporter activity
LDO37_RS04775	COG1846	Transcriptional regulator
LDO37_RS04775	COG1940	carbohydrate kinase activity
LDO37_RS04780	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LDO37_RS04785	COG0363	glucosamine-6-phosphate deaminase activity
LDO37_RS04790	COG2190	(PTS) system
LDO37_RS04790	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LDO37_RS04790	COG1263	PTS System
LDO37_RS04795	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LDO37_RS04800	COG2801	Transposase and inactivated derivatives
LDO37_RS04810	COG2963	transposase activity
LDO37_RS04815	COG0735	belongs to the Fur family
LDO37_RS04825	COG0716	FMN binding
LDO37_RS04835	COG0596	Alpha beta hydrolase
LDO37_RS04840	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
LDO37_RS04845	COG0033	Phosphoglucomutase
LDO37_RS04855	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LDO37_RS04870	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
LDO37_RS04875	COG1053	succinate dehydrogenase
LDO37_RS04885	COG0567	Dehydrogenase, E1 component
LDO37_RS04890	COG0508	dehydrogenase complex catalyzes the overall conversion of
LDO37_RS04895	COG0045	succinate-CoA ligase (ADP-forming) activity
LDO37_RS04905	COG0859	PFAM glycosyl transferase family 9
LDO37_RS04910	COG1132	(ABC) transporter
LDO37_RS04915	COG0076	glutamate decarboxylase activity
LDO37_RS04935	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LDO37_RS04940	COG1121	(ABC) transporter
LDO37_RS04945	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
LDO37_RS04950	COG0739	heme binding
LDO37_RS04980	COG1560	Kdo2-lipid A biosynthetic process
LDO37_RS04990	COG3102	Protein conserved in bacteria
LDO37_RS04995	COG0788	formyltetrahydrofolate deformylase activity
LDO37_RS05005	COG1199	ATP-dependent helicase activity
LDO37_RS05010	COG1214	PFAM Peptidase M22, glycoprotease
LDO37_RS05025	COG0596	Alpha beta hydrolase
LDO37_RS05030	COG0318	PFAM AMP-dependent synthetase and ligase
LDO37_RS05035	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
LDO37_RS05050	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
LDO37_RS05055	COG2894	cell division
LDO37_RS05065	COG3100	YcgL domain-containing protein
LDO37_RS05070	COG2951	lytic endotransglycosylase activity
LDO37_RS05075	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LDO37_RS05095	COG0840	transmembrane signaling receptor activity
LDO37_RS05120	COG1175	transmembrane transport
LDO37_RS05125	COG0395	ABC-type sugar transport system, permease component
LDO37_RS05130	COG3842	ATPase activity
LDO37_RS05150	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LDO37_RS05155	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
LDO37_RS05160	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
LDO37_RS05170	COG0431	NADPH-dependent FMN reductase
LDO37_RS05185	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
LDO37_RS05195	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LDO37_RS05200	COG2204	response regulator
LDO37_RS05210	COG0544	peptidyl-prolyl cis-trans isomerase activity
LDO37_RS05225	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
LDO37_RS05230	COG0776	regulation of translation
LDO37_RS05235	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LDO37_RS05240	COG1555	photosystem II stabilization
LDO37_RS05255	COG0232	Belongs to the dGTPase family. Type 2 subfamily
LDO37_RS05260	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
LDO37_RS05265	COG0436	Aminotransferase
LDO37_RS05270	COG1169	isochorismate synthase
LDO37_RS05275	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
LDO37_RS05315	COG0477	Major facilitator Superfamily
LDO37_RS05330	COG0280	phosphate acetyltransferase
LDO37_RS05330	COG0857	belongs to the CobB CobQ family
LDO37_RS05335	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LDO37_RS05340	COG3092	negative regulation of chromosome organization
LDO37_RS05350	COG4120	Belongs to the binding-protein-dependent transport system permease family
LDO37_RS05355	COG1122	ATPase activity
LDO37_RS05360	COG2203	Gaf domain
LDO37_RS05360	COG2199	diguanylate cyclase activity
LDO37_RS05365	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LDO37_RS05370	COG0653	protein targeting
LDO37_RS05380	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LDO37_RS05385	COG2186	Transcriptional regulator
LDO37_RS05395	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LDO37_RS05395	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LDO37_RS05400	COG0489	protein tyrosine kinase activity
LDO37_RS05405	COG5492	domain, Protein
LDO37_RS05410	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
LDO37_RS05415	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LDO37_RS05420	COG3715	PTS system
LDO37_RS05425	COG3716	PTS system mannose fructose sorbose family IID component
LDO37_RS05430	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
LDO37_RS05430	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LDO37_RS05435	COG0730	response to heat
LDO37_RS05445	COG0572	uridine kinase
LDO37_RS05450	COG2982	Protein involved in outer membrane biogenesis
LDO37_RS05460	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
LDO37_RS05465	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LDO37_RS05470	COG3738	Protein conserved in bacteria
LDO37_RS05475	COG0659	secondary active sulfate transmembrane transporter activity
LDO37_RS05480	COG1530	ribonuclease E activity
LDO37_RS05485	COG0564	pseudouridine synthase activity
LDO37_RS05490	COG0424	maF-like protein
LDO37_RS05495	COG1399	metal-binding, possibly nucleic acid-binding protein
LDO37_RS05505	COG0416	fatty acid biosynthetic process
LDO37_RS05510	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LDO37_RS05515	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LDO37_RS05535	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LDO37_RS05540	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LDO37_RS05545	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LDO37_RS05555	COG0084	hydrolase, TatD family'
LDO37_RS05560	COG1263	PTS System
LDO37_RS05560	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LDO37_RS05565	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
LDO37_RS05570	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LDO37_RS05585	COG3721	Heme iron utilization protein
LDO37_RS05590	COG0748	coenzyme F420 binding
LDO37_RS05605	COG0733	neurotransmitter:sodium symporter activity
LDO37_RS05615	COG4667	esterase of the alpha-beta hydrolase superfamily
LDO37_RS05625	COG1940	carbohydrate kinase activity
LDO37_RS05630	COG0784	Response regulator, receiver
LDO37_RS05630	COG0835	chemotaxis
LDO37_RS05635	COG1028	Short-chain dehydrogenase reductase Sdr
LDO37_RS05640	COG0616	signal peptide processing
LDO37_RS05650	COG0539	negative regulation of cytoplasmic translation
LDO37_RS05660	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
LDO37_RS05665	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
LDO37_RS05710	COG0583	DNA-binding transcription factor activity
LDO37_RS05720	COG0686	Belongs to the AlaDH PNT family
LDO37_RS05735	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
LDO37_RS05740	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LDO37_RS05750	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LDO37_RS05760	COG0156	8-amino-7-oxononanoate synthase activity
LDO37_RS05765	COG2226	methyltransferase
LDO37_RS05770	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
LDO37_RS05780	COG0501	Belongs to the peptidase M48B family
LDO37_RS05790	COG1028	Short-chain dehydrogenase reductase Sdr
LDO37_RS05805	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LDO37_RS05830	COG3923	Primosomal replication protein n
LDO37_RS05835	COG0730	response to heat
LDO37_RS05840	COG1199	ATP-dependent helicase activity
LDO37_RS05845	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
LDO37_RS05855	COG0587	DNA-directed DNA polymerase activity
LDO37_RS05875	COG1757	Na H antiporter
LDO37_RS05890	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LDO37_RS05895	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LDO37_RS05900	COG0131	Imidazoleglycerol-phosphate dehydratase
LDO37_RS05900	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
LDO37_RS05905	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LDO37_RS05910	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
LDO37_RS05920	COG0140	phosphoribosyl-ATP diphosphatase activity
LDO37_RS05920	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LDO37_RS05925	COG3012	SEC-C Motif Domain Protein
LDO37_RS05930	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
LDO37_RS05935	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LDO37_RS05940	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LDO37_RS05945	COG0215	cysteine-tRNA ligase activity
LDO37_RS05950	COG1435	thymidine kinase activity
LDO37_RS05965	COG0189	ligase activity
LDO37_RS05965	COG4067	protein conserved in archaea
LDO37_RS05970	COG0500	methyltransferase
LDO37_RS05975	COG4106	trans-aconitate 2-methyltransferase activity
LDO37_RS05980	COG1801	Protein of unknown function DUF72
LDO37_RS05990	COG0217	transcriptional regulatory protein
LDO37_RS05995	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
LDO37_RS06000	COG0632	four-way junction helicase activity
LDO37_RS06005	COG2255	four-way junction helicase activity
LDO37_RS06010	COG1271	oxidase subunit
LDO37_RS06015	COG1294	oxidase, subunit
LDO37_RS06020	COG4890	Cyd operon protein YbgT
LDO37_RS06030	COG0824	Thioesterase
LDO37_RS06035	COG0811	peptide transport
LDO37_RS06050	COG0823	Involved in the tonB-independent uptake of proteins
LDO37_RS06055	COG2885	chlorophyll binding
LDO37_RS06060	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
LDO37_RS06065	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
LDO37_RS06075	COG2205	protein histidine kinase activity
LDO37_RS06075	COG0784	Response regulator, receiver
LDO37_RS06110	COG1074	ATP-dependent DNA helicase activity
LDO37_RS06125	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LDO37_RS06135	COG1032	radical SAM domain protein
LDO37_RS06150	COG5001	Diguanylate cyclase
LDO37_RS06165	COG0583	DNA-binding transcription factor activity
LDO37_RS06170	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LDO37_RS06180	COG3313	Fe-S protein
LDO37_RS06235	COG2873	o-acetylhomoserine
LDO37_RS06240	COG1522	sequence-specific DNA binding
LDO37_RS06245	COG2205	protein histidine kinase activity
LDO37_RS06275	COG1061	Type III restriction enzyme res subunit
LDO37_RS06285	COG2814	Major facilitator Superfamily
LDO37_RS06295	COG0702	epimerase
LDO37_RS06305	COG1136	(ABC) transporter
LDO37_RS06325	COG0708	Exodeoxyribonuclease III
LDO37_RS06340	COG1120	ATPase activity
LDO37_RS06350	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LDO37_RS06370	COG1028	Short-chain dehydrogenase reductase Sdr
LDO37_RS06390	COG3385	transposase activity
LDO37_RS06400	COG3040	lipid binding
LDO37_RS06430	COG0697	spore germination
LDO37_RS06440	COG3718	enzyme involved in inositol metabolism
LDO37_RS06445	COG0673	inositol 2-dehydrogenase activity
LDO37_RS06470	COG3655	Transcriptional regulator
LDO37_RS06475	COG0673	inositol 2-dehydrogenase activity
LDO37_RS06480	COG0191	fructose-bisphosphate aldolase activity
LDO37_RS06490	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LDO37_RS06495	COG0673	inositol 2-dehydrogenase activity
LDO37_RS06500	COG3962	Belongs to the TPP enzyme family
LDO37_RS06505	COG1082	Xylose isomerase domain protein TIM barrel
LDO37_RS06510	COG1172	Belongs to the binding-protein-dependent transport system permease family
LDO37_RS06525	COG1609	Transcriptional regulator
LDO37_RS06570	COG2850	peptidyl-arginine hydroxylation
LDO37_RS06585	COG0840	transmembrane signaling receptor activity
LDO37_RS06590	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LDO37_RS06615	COG1278	Cold shock
LDO37_RS06620	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
LDO37_RS06625	COG0542	response to heat
LDO37_RS06635	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LDO37_RS06640	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
LDO37_RS06645	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
LDO37_RS06665	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LDO37_RS06675	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LDO37_RS06680	COG0297	glycogen (starch) synthase activity
LDO37_RS06685	COG0596	Alpha beta hydrolase
LDO37_RS06695	COG3070	regulator of competence-specific genes
LDO37_RS06710	COG0745	RESPONSE REGULATOR receiver
LDO37_RS06715	COG1434	Gram-negative-bacterium-type cell wall biogenesis
LDO37_RS06720	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LDO37_RS06725	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
LDO37_RS06730	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
LDO37_RS06735	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
LDO37_RS06775	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LDO37_RS06795	COG2205	protein histidine kinase activity
LDO37_RS06795	COG0784	Response regulator, receiver
LDO37_RS06800	COG1858	cytochrome C peroxidase
LDO37_RS06805	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LDO37_RS06820	COG0291	Belongs to the bacterial ribosomal protein bL35 family
LDO37_RS06825	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LDO37_RS06835	COG2824	Alkylphosphonate utilization operon protein PhnA
LDO37_RS06855	COG2198	Histidine kinase
LDO37_RS06855	COG0784	Response regulator, receiver
LDO37_RS06855	COG0643	Histidine kinase
LDO37_RS06875	COG0019	diaminopimelate decarboxylase activity
LDO37_RS06880	COG1609	Transcriptional regulator
LDO37_RS06890	COG1172	Belongs to the binding-protein-dependent transport system permease family
LDO37_RS07015	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LDO37_RS07020	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LDO37_RS07035	COG1309	transcriptional regulator
LDO37_RS07050	COG0840	transmembrane signaling receptor activity
LDO37_RS07055	COG2203	Gaf domain
LDO37_RS07055	COG3706	GGDEF domain
LDO37_RS07055	COG4251	negative regulation of phosphorylation
LDO37_RS07055	COG5001	Diguanylate cyclase
LDO37_RS07065	COG0784	Response regulator, receiver
LDO37_RS07065	COG5002	protein histidine kinase activity
LDO37_RS07065	COG2205	protein histidine kinase activity
LDO37_RS07075	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LDO37_RS07100	COG2989	Protein conserved in bacteria
LDO37_RS07105	COG3108	Peptidase M15
LDO37_RS07110	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LDO37_RS07125	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
LDO37_RS07145	COG2197	response regulator
LDO37_RS07150	COG1846	Transcriptional regulator
LDO37_RS07155	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LDO37_RS07160	COG2176	DNA-directed DNA polymerase activity
LDO37_RS07165	COG0517	IMP dehydrogenase activity
LDO37_RS07170	COG1448	Aminotransferase
LDO37_RS07175	COG3437	response regulator, receiver
LDO37_RS07175	COG2770	Histidine kinase
LDO37_RS07180	COG0017	Asparaginyl-tRNA synthetase
LDO37_RS07185	COG0840	transmembrane signaling receptor activity
LDO37_RS07200	COG0720	synthase
LDO37_RS07210	COG1760	l-serine dehydratase
LDO37_RS07215	COG0814	amino acid
LDO37_RS07220	COG0494	nUDIX hydrolase
LDO37_RS07230	COG0784	Response regulator, receiver
LDO37_RS07230	COG2198	Histidine kinase
LDO37_RS07230	COG2205	protein histidine kinase activity
LDO37_RS07250	COG3106	COG3106 Predicted ATPase
LDO37_RS07255	COG3768	UPF0283 membrane protein
LDO37_RS07265	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LDO37_RS07300	COG1454	alcohol dehydrogenase
LDO37_RS07315	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
LDO37_RS07350	COG0443	Heat shock 70 kDa protein
LDO37_RS07355	COG0443	Heat shock 70 kDa protein
LDO37_RS07365	COG3706	GGDEF domain
LDO37_RS07380	COG2304	oxidoreductase activity
LDO37_RS07410	COG2801	Transposase and inactivated derivatives
LDO37_RS07490	COG3185	4-Hydroxyphenylpyruvate dioxygenase
LDO37_RS07490	COG1082	Xylose isomerase domain protein TIM barrel
LDO37_RS07500	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
LDO37_RS07510	COG1802	Transcriptional regulator
LDO37_RS07515	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LDO37_RS07520	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
LDO37_RS07525	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
LDO37_RS07535	COG2828	Protein conserved in bacteria
LDO37_RS07545	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LDO37_RS07550	COG2159	amidohydrolase
LDO37_RS07570	COG0667	Aldo Keto reductase
LDO37_RS07600	COG4628	conserved protein (DUF2132)
LDO37_RS07620	COG2721	sulfolactate sulfo-lyase activity
LDO37_RS07630	COG2188	Transcriptional regulator
LDO37_RS07635	COG1063	alcohol dehydrogenase
LDO37_RS07640	COG1028	Short-chain dehydrogenase reductase Sdr
LDO37_RS07645	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LDO37_RS07650	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
LDO37_RS07650	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
LDO37_RS07655	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
LDO37_RS07670	COG1609	Transcriptional regulator
LDO37_RS07675	COG0583	DNA-binding transcription factor activity
LDO37_RS07690	COG4964	Belongs to the GSP D family
LDO37_RS07740	COG2885	chlorophyll binding
LDO37_RS07740	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
LDO37_RS07755	COG2186	Transcriptional regulator
LDO37_RS07760	COG3842	ATPase activity
LDO37_RS07770	COG1175	transmembrane transport
LDO37_RS07775	COG0395	ABC-type sugar transport system, permease component
LDO37_RS07780	COG2706	6-phosphogluconolactonase activity
LDO37_RS07790	COG1070	Carbohydrate kinase
LDO37_RS07800	COG3623	hexulose-6-phosphate isomerase
LDO37_RS07805	COG0235	Class ii aldolase
LDO37_RS07815	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LDO37_RS07820	COG1643	Atp-dependent helicase
LDO37_RS07865	COG3321	synthase
LDO37_RS07865	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LDO37_RS07865	COG0300	oxidoreductase activity
LDO37_RS07865	COG1028	Short-chain dehydrogenase reductase Sdr
LDO37_RS07865	COG0318	PFAM AMP-dependent synthetase and ligase
LDO37_RS07880	COG5001	Diguanylate cyclase
LDO37_RS07880	COG3300	MHYT domain
LDO37_RS07885	COG3622	Belongs to the hyi family
LDO37_RS07890	COG1115	amino acid carrier protein
LDO37_RS07895	COG0277	FAD linked oxidase domain protein
LDO37_RS07900	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
LDO37_RS07900	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LDO37_RS07910	COG2801	Transposase and inactivated derivatives
LDO37_RS07915	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LDO37_RS07935	COG4821	SIS domain
LDO37_RS07940	COG2207	Transcriptional regulator
LDO37_RS07940	COG4753	response regulator
LDO37_RS07965	COG1115	amino acid carrier protein
LDO37_RS07970	COG1028	Short-chain dehydrogenase reductase Sdr
LDO37_RS07995	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LDO37_RS08005	COG3290	protein histidine kinase activity
LDO37_RS08010	COG4565	transcriptional regulatory protein
LDO37_RS08050	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
LDO37_RS08055	COG0372	Belongs to the citrate synthase family
LDO37_RS08060	COG2079	MmgE PrpD family protein
LDO37_RS08080	COG0602	queuosine metabolic process
LDO37_RS08090	COG3706	GGDEF domain
LDO37_RS08125	COG1012	belongs to the aldehyde dehydrogenase family
LDO37_RS08140	COG4176	ABC-type proline glycine betaine transport system permease component
LDO37_RS08145	COG4175	Glycine betaine
LDO37_RS08145	COG3448	diguanylate cyclase activity
LDO37_RS08155	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LDO37_RS08160	COG1760	l-serine dehydratase
LDO37_RS08190	COG1063	alcohol dehydrogenase
LDO37_RS08205	COG1902	pentaerythritol trinitrate reductase activity
LDO37_RS08205	COG0446	pyridine nucleotide-disulphide oxidoreductase
LDO37_RS08210	COG2181	nitrate reductase activity
LDO37_RS08210	COG0247	lactate metabolic process
LDO37_RS08215	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
LDO37_RS08240	COG1785	Belongs to the alkaline phosphatase family
LDO37_RS08275	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LDO37_RS08295	COG3291	Pkd domain containing protein
LDO37_RS08295	COG3525	Glycosyl hydrolase, family 20, catalytic domain
LDO37_RS08300	COG0702	epimerase
LDO37_RS08305	COG1280	lysine exporter protein (LysE YggA)
LDO37_RS08315	COG0784	Response regulator, receiver
LDO37_RS08315	COG2205	protein histidine kinase activity
LDO37_RS08315	COG5002	protein histidine kinase activity
LDO37_RS08320	COG0745	RESPONSE REGULATOR receiver
LDO37_RS08325	COG2203	Gaf domain
LDO37_RS08325	COG2199	diguanylate cyclase activity
LDO37_RS08325	COG2200	EAL domain
LDO37_RS08330	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LDO37_RS08335	COG1215	transferase activity, transferring glycosyl groups
LDO37_RS08340	COG0438	transferase activity, transferring glycosyl groups
LDO37_RS08350	COG0438	transferase activity, transferring glycosyl groups
LDO37_RS08355	COG0110	maltose O-acetyltransferase activity
LDO37_RS08365	COG0438	transferase activity, transferring glycosyl groups
LDO37_RS08370	COG0438	transferase activity, transferring glycosyl groups
LDO37_RS08375	COG2204	response regulator
LDO37_RS08380	COG3850	Histidine kinase
LDO37_RS08380	COG4999	Histidine kinase
LDO37_RS08380	COG2205	protein histidine kinase activity
LDO37_RS08380	COG3437	response regulator, receiver
LDO37_RS08385	COG0745	RESPONSE REGULATOR receiver
LDO37_RS08390	COG0489	protein tyrosine kinase activity
LDO37_RS08415	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
LDO37_RS08420	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
LDO37_RS08430	COG1028	Short-chain dehydrogenase reductase Sdr
LDO37_RS08435	COG1164	Oligoendopeptidase f
LDO37_RS08445	COG4139	cobalamin transport
LDO37_RS08450	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
LDO37_RS08510	COG0513	Belongs to the DEAD box helicase family
LDO37_RS08525	COG0583	DNA-binding transcription factor activity
LDO37_RS08535	COG1366	Belongs to the anti-sigma-factor antagonist family
LDO37_RS08540	COG1366	Belongs to the anti-sigma-factor antagonist family
LDO37_RS08545	COG2172	sigma factor antagonist activity
LDO37_RS08555	COG2205	protein histidine kinase activity
LDO37_RS08555	COG3437	response regulator, receiver
LDO37_RS08555	COG3850	Histidine kinase
LDO37_RS08555	COG4999	Histidine kinase
LDO37_RS08560	COG3437	response regulator, receiver
LDO37_RS08575	COG1451	nucleotide metabolic process
LDO37_RS08595	COG0840	transmembrane signaling receptor activity
LDO37_RS08675	COG2195	Cleaves the N-terminal amino acid of tripeptides
LDO37_RS08690	COG2199	diguanylate cyclase activity
LDO37_RS08705	COG2200	EAL domain
LDO37_RS08705	COG2199	diguanylate cyclase activity
LDO37_RS08725	COG0724	RNA recognition motif
LDO37_RS08735	COG1793	dna ligase
LDO37_RS08745	COG0534	Mate efflux family protein
LDO37_RS08750	COG0307	riboflavin synthase, alpha
LDO37_RS08760	COG3001	Fructosamine kinase
LDO37_RS08770	COG3706	GGDEF domain
LDO37_RS08780	COG0791	NLP P60 protein
LDO37_RS08795	COG3148	PFAM DTW domain containing protein
LDO37_RS08800	COG1940	carbohydrate kinase activity
LDO37_RS08805	COG2204	response regulator
LDO37_RS08810	COG3852	Histidine kinase
LDO37_RS08820	COG1858	cytochrome C peroxidase
LDO37_RS08825	COG1858	cytochrome C peroxidase
LDO37_RS08830	COG0723	plastoquinol--plastocyanin reductase activity
LDO37_RS08850	COG0303	'Molybdopterin
LDO37_RS08855	COG0746	molybdenum cofactor guanylyltransferase activity
LDO37_RS08860	COG3842	ATPase activity
LDO37_RS08865	COG4662	Binding-protein-dependent transport system inner membrane component
LDO37_RS08875	COG2204	response regulator
LDO37_RS08880	COG3852	Histidine kinase
LDO37_RS08885	COG0488	(ABC) transporter
LDO37_RS08895	COG1175	transmembrane transport
LDO37_RS08900	COG0395	ABC-type sugar transport system, permease component
LDO37_RS08905	COG3842	ATPase activity
LDO37_RS08910	COG0246	Mannitol dehydrogenase
LDO37_RS08920	COG1070	Carbohydrate kinase
LDO37_RS08945	COG0456	acetyltransferase
LDO37_RS08965	COG0840	transmembrane signaling receptor activity
LDO37_RS08970	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LDO37_RS09000	COG3383	formate dehydrogenase (NAD+) activity
LDO37_RS09000	COG0243	molybdopterin cofactor binding
LDO37_RS09005	COG0437	4 iron, 4 sulfur cluster binding
LDO37_RS09010	COG2864	formate dehydrogenase
LDO37_RS09015	COG5002	protein histidine kinase activity
LDO37_RS09020	COG0004	ammonium transporteR
LDO37_RS09025	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LDO37_RS09030	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
LDO37_RS09040	COG1177	transmembrane transport
LDO37_RS09050	COG3842	ATPase activity
LDO37_RS09075	COG1486	melibiose metabolic process
LDO37_RS09080	COG0037	tRNA processing
LDO37_RS09085	COG0589	response to stress
LDO37_RS09090	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LDO37_RS09105	COG2217	Heavy metal translocating P-type atpase
LDO37_RS09115	COG2010	Cytochrome c
LDO37_RS09130	COG3278	Belongs to the heme-copper respiratory oxidase family
LDO37_RS09145	COG2205	protein histidine kinase activity
LDO37_RS09145	COG0784	Response regulator, receiver
LDO37_RS09160	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LDO37_RS09170	COG3568	Endonuclease Exonuclease Phosphatase
LDO37_RS09185	COG3120	sequence-specific DNA binding
LDO37_RS09190	COG1067	ATP-dependent peptidase activity
LDO37_RS09195	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LDO37_RS09210	COG0488	(ABC) transporter
LDO37_RS09220	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LDO37_RS09220	COG0116	Belongs to the methyltransferase superfamily
LDO37_RS09230	COG0167	dihydroorotate dehydrogenase activity
LDO37_RS09235	COG2902	Dehydrogenase
LDO37_RS09245	COG0308	aminopeptidase N
LDO37_RS09260	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
LDO37_RS09265	COG1956	GAF domain-containing protein
LDO37_RS09270	COG1132	(ABC) transporter
LDO37_RS09275	COG2995	paraquat-inducible protein a
LDO37_RS09280	COG3008	intermembrane lipid transfer
LDO37_RS09285	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
LDO37_RS09285	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LDO37_RS09305	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LDO37_RS09310	COG1666	GTP binding
LDO37_RS09315	COG1648	precorrin-2 dehydrogenase activity
LDO37_RS09315	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LDO37_RS09320	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LDO37_RS09325	COG4597	amino acid ABC transporter
LDO37_RS09330	COG0765	amino acid transport
LDO37_RS09335	COG1126	abc transporter atp-binding protein
LDO37_RS09340	COG0670	Belongs to the BI1 family
LDO37_RS09345	COG2920	part of a sulfur-relay system
LDO37_RS09350	COG1254	Belongs to the acylphosphatase family
LDO37_RS09455	COG0631	protein serine/threonine phosphatase activity
LDO37_RS09490	COG2815	serine threonine protein kinase
LDO37_RS09490	COG0515	serine threonine protein kinase
LDO37_RS09505	COG3706	GGDEF domain
LDO37_RS09515	COG2010	Cytochrome c
LDO37_RS09525	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LDO37_RS09530	COG1309	transcriptional regulator
LDO37_RS09555	COG2925	Exonuclease
LDO37_RS09560	COG1380	Effector of murein hydrolase LrgA
LDO37_RS09565	COG1346	cytolysis
LDO37_RS09575	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
LDO37_RS09580	COG2963	transposase activity
LDO37_RS09590	COG0500	methyltransferase
LDO37_RS09605	COG0776	regulation of translation
LDO37_RS09615	COG1136	(ABC) transporter
LDO37_RS09635	COG0072	phenylalanine-tRNA ligase activity
LDO37_RS09635	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LDO37_RS09665	COG2133	pyrroloquinoline quinone binding
LDO37_RS09685	COG2350	Protein conserved in bacteria
LDO37_RS09695	COG4134	Bacterial extracellular solute-binding protein
LDO37_RS09700	COG4135	transport system, permease component
LDO37_RS09705	COG4136	ATPase activity
LDO37_RS09710	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LDO37_RS09730	COG0300	oxidoreductase activity
LDO37_RS09735	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LDO37_RS09740	COG2207	Transcriptional regulator
LDO37_RS09745	COG0351	phosphomethylpyrimidine kinase
LDO37_RS09750	COG1116	anion transmembrane transporter activity
LDO37_RS09755	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LDO37_RS09760	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LDO37_RS09765	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LDO37_RS09770	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
LDO37_RS09810	COG4397	Mu-like prophage major head subunit gpT
LDO37_RS09835	COG0116	Belongs to the methyltransferase superfamily
LDO37_RS09835	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LDO37_RS09840	COG0564	pseudouridine synthase activity
LDO37_RS09850	COG0733	neurotransmitter:sodium symporter activity
LDO37_RS09860	COG0626	cystathionine gamma-synthase activity
LDO37_RS09865	COG0519	Catalyzes the synthesis of GMP from XMP
LDO37_RS09895	COG1842	Phage shock protein A
LDO37_RS09900	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
LDO37_RS09910	COG4168	peptide transport system, permease
LDO37_RS09915	COG4171	peptide transport system, permease
LDO37_RS09925	COG4172	Belongs to the ABC transporter superfamily
LDO37_RS09975	COG0519	Catalyzes the synthesis of GMP from XMP
LDO37_RS09980	COG0745	RESPONSE REGULATOR receiver
LDO37_RS09990	COG1263	PTS System
LDO37_RS09990	COG2190	(PTS) system
LDO37_RS09990	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LDO37_RS09995	COG0840	transmembrane signaling receptor activity
LDO37_RS10010	COG1227	inorganic diphosphatase activity
LDO37_RS10015	COG0167	dihydroorotate dehydrogenase activity
LDO37_RS10030	COG0243	molybdopterin cofactor binding
LDO37_RS10035	COG3005	denitrification pathway
LDO37_RS10040	COG4459	periplasmic nitrate reductase
LDO37_RS10045	COG0390	transport system, permease component
LDO37_RS10050	COG2205	protein histidine kinase activity
LDO37_RS10050	COG2202	Pas domain
LDO37_RS10080	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
LDO37_RS10085	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
LDO37_RS10095	COG3901	Regulator of nitric oxide reductase transcription
LDO37_RS10095	COG0348	domain, Protein
LDO37_RS10135	COG1129	ABC transporter
LDO37_RS10135	COG0842	Transport permease protein
LDO37_RS10155	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LDO37_RS10160	COG1434	Gram-negative-bacterium-type cell wall biogenesis
LDO37_RS10190	COG3706	GGDEF domain
LDO37_RS10200	COG0322	excinuclease ABC activity
LDO37_RS10205	COG2197	response regulator
LDO37_RS10210	COG0417	DNA replication proofreading
LDO37_RS10220	COG4067	protein conserved in archaea
LDO37_RS10220	COG0189	ligase activity
LDO37_RS10225	COG0189	ligase activity
LDO37_RS10235	COG1760	l-serine dehydratase
LDO37_RS10240	COG4943	cyclic-guanylate-specific phosphodiesterase activity
LDO37_RS10270	COG0009	L-threonylcarbamoyladenylate synthase
LDO37_RS10275	COG0613	PHP domain protein
LDO37_RS10285	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LDO37_RS10290	COG0512	Glutamine amidotransferase of anthranilate synthase
LDO37_RS10295	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LDO37_RS10300	COG0135	phosphoribosylanthranilate isomerase activity
LDO37_RS10300	COG0134	indole-3-glycerol-phosphate synthase activity
LDO37_RS10305	COG0133	tryptophan synthase activity
LDO37_RS10310	COG0159	tryptophan synthase activity
LDO37_RS10315	COG1301	dicarboxylic acid transport
LDO37_RS10325	COG0508	dehydrogenase complex catalyzes the overall conversion of
LDO37_RS10325	COG0596	Alpha beta hydrolase
LDO37_RS10375	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LDO37_RS10380	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
LDO37_RS10390	COG4948	Mandelate Racemase Muconate Lactonizing
LDO37_RS10395	COG2721	sulfolactate sulfo-lyase activity
LDO37_RS10405	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LDO37_RS10410	COG3842	ATPase activity
LDO37_RS10415	COG0395	ABC-type sugar transport system, permease component
LDO37_RS10420	COG1175	transmembrane transport
LDO37_RS10430	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LDO37_RS10450	COG0673	inositol 2-dehydrogenase activity
LDO37_RS10480	COG0183	Belongs to the thiolase family
LDO37_RS10510	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LDO37_RS10515	COG2181	nitrate reductase activity
LDO37_RS10515	COG0247	lactate metabolic process
LDO37_RS10520	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
LDO37_RS10525	COG2086	electron transfer activity
LDO37_RS10585	COG0488	(ABC) transporter
LDO37_RS10600	COG4948	Mandelate Racemase Muconate Lactonizing
LDO37_RS10605	COG0179	Fumarylacetoacetate (FAA) hydrolase
LDO37_RS10620	COG3618	amidohydrolase
LDO37_RS10635	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LDO37_RS10640	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LDO37_RS10645	COG0363	glucosamine-6-phosphate deaminase activity
LDO37_RS10660	COG0246	Mannitol dehydrogenase
LDO37_RS10675	COG1609	Transcriptional regulator
LDO37_RS10680	COG3842	ATPase activity
LDO37_RS10685	COG0366	Alpha amylase catalytic
LDO37_RS10690	COG0395	ABC-type sugar transport system, permease component
LDO37_RS10695	COG1175	transmembrane transport
LDO37_RS10700	COG1653	transport
LDO37_RS10705	COG2188	Transcriptional regulator
LDO37_RS10715	COG0010	Belongs to the arginase family
LDO37_RS10720	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
LDO37_RS10725	COG2986	histidine ammonia-lyase
LDO37_RS10735	COG3706	GGDEF domain
LDO37_RS10750	COG0277	FAD linked oxidase domain protein
LDO37_RS10750	COG0247	lactate metabolic process
LDO37_RS10775	COG3385	transposase activity
LDO37_RS10785	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
LDO37_RS10790	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LDO37_RS10795	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LDO37_RS10820	COG2267	carboxylic ester hydrolase activity
LDO37_RS10830	COG1028	Short-chain dehydrogenase reductase Sdr
LDO37_RS10840	COG0454	-acetyltransferase
LDO37_RS10845	COG1028	Short-chain dehydrogenase reductase Sdr
LDO37_RS10850	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LDO37_RS10860	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
LDO37_RS10865	COG1643	Atp-dependent helicase
LDO37_RS10870	COG0281	malic enzyme
LDO37_RS10880	COG2949	membrane
LDO37_RS10905	COG0492	ferredoxin-NADP+ reductase activity
LDO37_RS10910	COG4988	ABC transporter
LDO37_RS10915	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
LDO37_RS10920	COG1879	ABC-type sugar transport system periplasmic component
LDO37_RS10950	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LDO37_RS10975	COG4608	Belongs to the ABC transporter superfamily
LDO37_RS10980	COG0444	Belongs to the ABC transporter superfamily
LDO37_RS10985	COG4166	transmembrane transport
LDO37_RS10990	COG4239	(ABC) transporter, permease
LDO37_RS10995	COG4174	ABC transporter (Permease)
LDO37_RS11000	COG3070	regulator of competence-specific genes
LDO37_RS11020	COG0076	glutamate decarboxylase activity
LDO37_RS11025	COG1737	Transcriptional regulator
LDO37_RS11030	COG1454	alcohol dehydrogenase
LDO37_RS11035	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
LDO37_RS11050	COG1960	acyl-CoA dehydrogenase activity
LDO37_RS11055	COG1309	transcriptional regulator
LDO37_RS11100	COG1882	Formate acetyltransferase
LDO37_RS11115	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LDO37_RS11125	COG3013	Belongs to the UPF0304 family
LDO37_RS11130	COG2766	serine protein kinase
LDO37_RS11135	COG2718	Belongs to the UPF0229 family
LDO37_RS11140	COG2719	SpoVR family
LDO37_RS11160	COG0463	Glycosyl transferase, family 2
LDO37_RS11175	COG2835	tetraacyldisaccharide 4'-kinase activity
LDO37_RS11180	COG1663	tetraacyldisaccharide 4'-kinase activity
LDO37_RS11185	COG1132	(ABC) transporter
LDO37_RS11190	COG0658	competence protein
LDO37_RS11190	COG2333	competence protein COMEC
LDO37_RS11200	COG4591	ABC-type transport system involved in lipoprotein release permease component
LDO37_RS11205	COG1136	(ABC) transporter
LDO37_RS11210	COG4591	ABC-type transport system involved in lipoprotein release permease component
LDO37_RS11220	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LDO37_RS11235	COG1252	NADH dehydrogenase
LDO37_RS11240	COG2165	general secretion pathway protein
LDO37_RS11270	COG0537	adenosine 5'-monophosphoramidase activity
LDO37_RS11275	COG0840	transmembrane signaling receptor activity
LDO37_RS11300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LDO37_RS11300	COG4191	Histidine kinase
LDO37_RS11305	COG0471	metal ion transport
LDO37_RS11320	COG5001	Diguanylate cyclase
LDO37_RS11320	COG1716	ATPase activity
LDO37_RS11325	COG0784	Response regulator, receiver
LDO37_RS11325	COG0835	chemotaxis
LDO37_RS11335	COG2205	protein histidine kinase activity
LDO37_RS11340	COG0745	RESPONSE REGULATOR receiver
LDO37_RS11350	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LDO37_RS11355	COG1079	Belongs to the binding-protein-dependent transport system permease family
LDO37_RS11360	COG4603	Belongs to the binding-protein-dependent transport system permease family
LDO37_RS11365	COG3845	ABC transporter
LDO37_RS11370	COG1744	ABC transporter substrate-binding protein PnrA-like
LDO37_RS11380	COG2205	protein histidine kinase activity
LDO37_RS11380	COG0784	Response regulator, receiver
LDO37_RS11395	COG3246	L-lysine catabolic process to acetate
LDO37_RS11400	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LDO37_RS11480	COG0657	acetylesterase activity
LDO37_RS11500	COG3321	synthase
LDO37_RS11500	COG0604	alcohol dehydrogenase
LDO37_RS11505	COG0583	DNA-binding transcription factor activity
LDO37_RS11515	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LDO37_RS11520	COG1845	cytochrome c oxidase, subunit III
LDO37_RS11525	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
LDO37_RS11530	COG0109	protoheme IX farnesyltransferase activity
LDO37_RS11585	COG0438	transferase activity, transferring glycosyl groups
LDO37_RS11635	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LDO37_RS11650	COG0242	peptide deformylase activity
LDO37_RS11655	COG2226	methyltransferase
LDO37_RS11685	COG2199	diguanylate cyclase activity
LDO37_RS11700	COG3126	Type III secretion system lipoprotein chaperone (YscW)
LDO37_RS11705	COG1946	Acyl-CoA thioesterase
LDO37_RS11710	COG1522	sequence-specific DNA binding
LDO37_RS11760	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
LDO37_RS11775	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LDO37_RS11785	COG0574	Belongs to the PEP-utilizing enzyme family
LDO37_RS11785	COG3848	Pyruvate phosphate dikinase
LDO37_RS11820	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LDO37_RS11825	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LDO37_RS11860	COG2963	transposase activity
LDO37_RS11865	COG0435	Glutathione S-transferase
LDO37_RS11885	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LDO37_RS11890	COG0601	transmembrane transport
LDO37_RS11905	COG0314	molybdopterin synthase activity
LDO37_RS11910	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
LDO37_RS11920	COG0521	Mo-molybdopterin cofactor biosynthetic process
LDO37_RS11925	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LDO37_RS11930	COG0391	Required for morphogenesis under gluconeogenic growth conditions
LDO37_RS11935	COG2198	Histidine kinase
LDO37_RS11940	COG2204	response regulator
LDO37_RS11945	COG0556	nucleotide-excision repair
LDO37_RS11995	COG4657	Part of a membrane complex involved in electron transport
LDO37_RS12005	COG4656	Part of a membrane complex involved in electron transport
LDO37_RS12010	COG4658	electron transport chain
LDO37_RS12015	COG4659	FMN binding
LDO37_RS12020	COG4660	Part of a membrane complex involved in electron transport
LDO37_RS12025	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LDO37_RS12030	COG4172	Belongs to the ABC transporter superfamily
LDO37_RS12040	COG0601	transmembrane transport
LDO37_RS12045	COG0747	negative chemotaxis
LDO37_RS12050	COG0346	lactoylglutathione lyase activity
LDO37_RS12060	COG2885	chlorophyll binding
LDO37_RS12065	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LDO37_RS12070	COG2056	Na+-H+ antiporter family
LDO37_RS12075	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
LDO37_RS12105	COG1012	belongs to the aldehyde dehydrogenase family
LDO37_RS12105	COG1454	alcohol dehydrogenase
LDO37_RS12110	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LDO37_RS12120	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LDO37_RS12125	COG0643	Histidine kinase
LDO37_RS12125	COG2198	Histidine kinase
LDO37_RS12135	COG3082	Protein of unknown function (DUF1414)
LDO37_RS12400	COG5377	YqaJ viral recombinase family
LDO37_RS12420	COG0596	Alpha beta hydrolase
LDO37_RS12420	COG0508	dehydrogenase complex catalyzes the overall conversion of
LDO37_RS12425	COG0022	dehydrogenase e1 component
LDO37_RS12430	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LDO37_RS12435	COG3199	ATP-NAD kinase
LDO37_RS12440	COG3284	Transcriptional regulator
LDO37_RS12450	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LDO37_RS12480	COG2258	MOSC domain
LDO37_RS12490	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LDO37_RS12520	COG0123	including yeast histone deacetylase and acetoin utilization protein
LDO37_RS12535	COG1473	amidohydrolase
LDO37_RS12550	COG1012	belongs to the aldehyde dehydrogenase family
LDO37_RS12560	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LDO37_RS12560	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LDO37_RS12565	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LDO37_RS12570	COG0583	DNA-binding transcription factor activity
LDO37_RS12575	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LDO37_RS12580	COG0778	Nitroreductase
LDO37_RS12585	COG1902	pentaerythritol trinitrate reductase activity
LDO37_RS12585	COG0446	pyridine nucleotide-disulphide oxidoreductase
LDO37_RS12590	COG0616	signal peptide processing
LDO37_RS12595	COG0252	asparaginase activity
LDO37_RS12600	COG3139	Protein of unknown function (DUF1315)
LDO37_RS12615	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LDO37_RS12620	COG0676	glucose-6-phosphate 1-epimerase activity
LDO37_RS12625	COG0745	RESPONSE REGULATOR receiver
LDO37_RS12630	COG2205	protein histidine kinase activity
LDO37_RS12645	COG2226	methyltransferase
LDO37_RS12665	COG1120	ATPase activity
LDO37_RS12670	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LDO37_RS12695	COG1012	belongs to the aldehyde dehydrogenase family
LDO37_RS12710	COG4176	ABC-type proline glycine betaine transport system permease component
LDO37_RS12715	COG4175	Glycine betaine
LDO37_RS12715	COG3448	diguanylate cyclase activity
LDO37_RS12740	COG2983	Belongs to the UPF0260 family
LDO37_RS12765	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LDO37_RS12770	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LDO37_RS12780	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LDO37_RS12785	COG2832	Protein of unknown function (DUF454)
LDO37_RS12795	COG0745	RESPONSE REGULATOR receiver
LDO37_RS12805	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LDO37_RS12810	COG1286	toxin biosynthetic process
LDO37_RS12815	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
LDO37_RS12820	COG0285	dihydrofolate synthase activity
LDO37_RS12830	COG0101	tRNA pseudouridine synthase activity
LDO37_RS12840	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LDO37_RS12845	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LDO37_RS12860	COG0745	RESPONSE REGULATOR receiver
LDO37_RS12865	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LDO37_RS12890	COG3101	peptidyl-lysine hydroxylation
LDO37_RS12895	COG2860	membrane
LDO37_RS12900	COG4221	oxidoreductase activity
LDO37_RS12905	COG0583	DNA-binding transcription factor activity
LDO37_RS12910	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
LDO37_RS12915	COG2890	protein-(glutamine-N5) methyltransferase activity
LDO37_RS12920	COG2840	Smr protein MutS2
LDO37_RS12925	COG2062	phosphohistidine phosphatase, SixA
LDO37_RS12935	COG0366	Alpha amylase catalytic
LDO37_RS12935	COG1470	cell adhesion involved in biofilm formation
LDO37_RS12940	COG0667	Aldo Keto reductase
LDO37_RS12945	COG1172	Belongs to the binding-protein-dependent transport system permease family
LDO37_RS12950	COG1129	ABC transporter
LDO37_RS12970	COG1349	DNA-binding transcription factor activity
LDO37_RS12975	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LDO37_RS12980	COG1070	Carbohydrate kinase
LDO37_RS12995	COG0183	Belongs to the thiolase family
LDO37_RS13000	COG1595	DNA-templated transcription, initiation
LDO37_RS13010	COG2067	long-chain fatty acid transport protein
LDO37_RS13015	COG5265	(ABC) transporter
LDO37_RS13020	COG2853	Lipoprotein
LDO37_RS13025	COG3088	subunit of a heme lyase
LDO37_RS13025	COG4235	cytochrome complex assembly
LDO37_RS13030	COG3088	subunit of a heme lyase
LDO37_RS13030	COG4235	cytochrome complex assembly
LDO37_RS13035	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LDO37_RS13040	COG1138	Cytochrome C-type biogenesis protein
LDO37_RS13045	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
LDO37_RS13050	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LDO37_RS13055	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LDO37_RS13060	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LDO37_RS13065	COG4133	protoheme IX ABC transporter activity
LDO37_RS13075	COG0835	chemotaxis
LDO37_RS13085	COG1192	Involved in chromosome partitioning
LDO37_RS13095	COG0643	Histidine kinase
LDO37_RS13095	COG2198	Histidine kinase
LDO37_RS13095	COG0784	Response regulator, receiver
LDO37_RS13100	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
LDO37_RS13140	COG1987	bacterial-type flagellum assembly
LDO37_RS13190	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LDO37_RS13200	COG1677	Flagellar hook-basal body complex protein FliE
LDO37_RS13220	COG1516	flagellar protein fliS
LDO37_RS13230	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
LDO37_RS13235	COG1334	flagellar protein FlaG
LDO37_RS13240	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LDO37_RS13250	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LDO37_RS13255	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LDO37_RS13260	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LDO37_RS13265	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LDO37_RS13270	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LDO37_RS13290	COG2837	iron assimilation
LDO37_RS13315	COG1393	Belongs to the ArsC family
LDO37_RS13325	COG1876	peptidase activity
LDO37_RS13335	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
LDO37_RS13340	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LDO37_RS13350	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LDO37_RS13365	COG4783	chaperone-mediated protein folding
LDO37_RS13370	COG1393	Belongs to the ArsC family
LDO37_RS13390	COG2233	PERMEase
LDO37_RS13405	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
LDO37_RS13420	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LDO37_RS13425	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
LDO37_RS13430	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LDO37_RS13440	COG3473	Maleate cis-trans isomerase
LDO37_RS13445	COG0179	Fumarylacetoacetate (FAA) hydrolase
LDO37_RS13465	COG0410	ABC transporter
LDO37_RS13470	COG0411	ABC transporter
LDO37_RS13510	COG0121	glutamine amidotransferase
LDO37_RS13515	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
LDO37_RS13520	COG1960	acyl-CoA dehydrogenase activity
LDO37_RS13535	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LDO37_RS13545	COG2226	methyltransferase
LDO37_RS13550	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LDO37_RS13555	COG0741	lytic transglycosylase activity
LDO37_RS13555	COG1388	LysM domain
LDO37_RS13570	COG0347	Belongs to the P(II) protein family
LDO37_RS13590	COG0825	malonyl-CoA metabolic process
LDO37_RS13595	COG0587	DNA-directed DNA polymerase activity
LDO37_RS13600	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LDO37_RS13615	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LDO37_RS13625	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
LDO37_RS13630	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LDO37_RS13635	COG0750	zinc metalloprotease
LDO37_RS13640	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
LDO37_RS13645	COG0575	Belongs to the CDS family
LDO37_RS13650	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LDO37_RS13675	COG0024	Methionine aminopeptidase
LDO37_RS13690	COG0564	pseudouridine synthase activity
LDO37_RS13695	COG3098	single-species biofilm formation
LDO37_RS13725	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
LDO37_RS13735	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
LDO37_RS13735	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
LDO37_RS13750	COG1611	Belongs to the LOG family
LDO37_RS13770	COG2363	Small membrane protein
LDO37_RS13780	COG0583	DNA-binding transcription factor activity
LDO37_RS13785	COG3152	Membrane
LDO37_RS13790	COG0301	tRNA thio-modification
LDO37_RS13790	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LDO37_RS13800	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
LDO37_RS13805	COG1722	exodeoxyribonuclease VII activity
LDO37_RS13810	COG0142	geranyltranstransferase activity
LDO37_RS13815	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LDO37_RS13825	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
LDO37_RS13835	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LDO37_RS13855	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LDO37_RS13855	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LDO37_RS13860	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LDO37_RS13865	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LDO37_RS13880	COG1073	alpha beta
LDO37_RS13885	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
LDO37_RS13890	COG2252	PERMEase
LDO37_RS13895	COG2195	Cleaves the N-terminal amino acid of tripeptides
LDO37_RS13905	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LDO37_RS13905	COG0047	phosphoribosylformylglycinamidine synthase activity
LDO37_RS13910	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
LDO37_RS13920	COG0583	DNA-binding transcription factor activity
LDO37_RS13935	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
LDO37_RS13955	COG4969	Belongs to the N-Me-Phe pilin family
LDO37_RS13965	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LDO37_RS13970	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LDO37_RS13975	COG0497	DNA recombination
LDO37_RS13980	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LDO37_RS13985	COG2914	Belongs to the UPF0125 (RnfH) family
LDO37_RS13990	COG2867	negative regulation of translational initiation
LDO37_RS14005	COG1396	sequence-specific DNA binding
LDO37_RS14020	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
LDO37_RS14040	COG0095	Lipoate-protein ligase
LDO37_RS14050	COG1842	Phage shock protein A
LDO37_RS14075	COG0754	glutathionylspermidine amidase activity
LDO37_RS14115	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LDO37_RS14140	COG0351	phosphomethylpyrimidine kinase
LDO37_RS14160	COG1187	pseudouridine synthase activity
LDO37_RS14165	COG2840	Smr protein MutS2
LDO37_RS14195	COG2877	3-deoxy-8-phosphooctulonate synthase activity
LDO37_RS14200	COG2912	Transglutaminase-like superfamily
LDO37_RS14210	COG2890	protein-(glutamine-N5) methyltransferase activity
LDO37_RS14215	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LDO37_RS14220	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
LDO37_RS14225	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
LDO37_RS14235	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LDO37_RS14240	COG0193	aminoacyl-tRNA hydrolase activity
LDO37_RS14325	COG2706	6-phosphogluconolactonase activity
LDO37_RS14330	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LDO37_RS14350	COG0395	ABC-type sugar transport system, permease component
LDO37_RS14355	COG1024	Enoyl-CoA hydratase
LDO37_RS14360	COG1028	Short-chain dehydrogenase reductase Sdr
LDO37_RS14370	COG3842	ATPase activity
LDO37_RS14380	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LDO37_RS14390	COG1702	phosphate starvation-inducible protein PhoH
LDO37_RS14400	COG4535	Mg2 and Co2 transporter CorC
LDO37_RS14405	COG0815	Transfers the fatty acyl group on membrane lipoproteins
LDO37_RS14415	COG2888	peptidyl-tyrosine sulfation
LDO37_RS14420	COG0495	leucyl-tRNA aminoacylation
LDO37_RS14425	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
LDO37_RS14430	COG1466	dna polymerase III delta subunit
LDO37_RS14435	COG0799	negative regulation of ribosome biogenesis
LDO37_RS14440	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LDO37_RS14445	COG0768	penicillin binding
LDO37_RS14450	COG0772	Belongs to the SEDS family
LDO37_RS14455	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LDO37_RS14460	COG1686	Belongs to the peptidase S11 family
LDO37_RS14470	COG0321	lipoyl(octanoyl) transferase activity
LDO37_RS14475	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LDO37_RS14485	COG0484	heat shock protein binding
LDO37_RS14495	COG1301	dicarboxylic acid transport
LDO37_RS14510	COG0366	Alpha amylase catalytic
LDO37_RS14515	COG1263	PTS System
LDO37_RS14515	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LDO37_RS14520	COG1609	Transcriptional regulator
LDO37_RS14530	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
LDO37_RS14540	COG2011	ABC-type metal ion transport system permease component
LDO37_RS14545	COG1464	Belongs to the NlpA lipoprotein family
LDO37_RS14550	COG1737	Transcriptional regulator
LDO37_RS14555	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LDO37_RS14560	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LDO37_RS14565	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
LDO37_RS14570	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
LDO37_RS14575	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LDO37_RS14585	COG1940	carbohydrate kinase activity
LDO37_RS14590	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LDO37_RS14595	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LDO37_RS14610	COG4948	Mandelate Racemase Muconate Lactonizing
LDO37_RS14625	COG2188	Transcriptional regulator
LDO37_RS14630	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LDO37_RS14640	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
LDO37_RS14640	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
LDO37_RS14645	COG2186	Transcriptional regulator
LDO37_RS14650	COG2205	protein histidine kinase activity
LDO37_RS14650	COG4999	Histidine kinase
LDO37_RS14650	COG3437	response regulator, receiver
LDO37_RS14650	COG3850	Histidine kinase
LDO37_RS14665	COG2200	EAL domain
LDO37_RS14685	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LDO37_RS14690	COG1115	amino acid carrier protein
LDO37_RS14695	COG1584	GPR1 FUN34 yaaH family protein
LDO37_RS14700	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LDO37_RS14700	COG0519	Catalyzes the synthesis of GMP from XMP
LDO37_RS14705	COG0516	GMP reductase activity
LDO37_RS14705	COG0517	IMP dehydrogenase activity
LDO37_RS14720	COG1160	GTP binding
LDO37_RS14725	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LDO37_RS14730	COG2976	Protein conserved in bacteria
LDO37_RS14735	COG0124	histidyl-tRNA synthetase
LDO37_RS14745	COG1426	Protein conserved in bacteria
LDO37_RS14750	COG3063	Type IV pilus biogenesis stability protein PilW
LDO37_RS14760	COG0105	UTP biosynthetic process
LDO37_RS14770	COG2975	iron-sulfur cluster assembly
LDO37_RS14775	COG0633	Ferredoxin
LDO37_RS14795	COG0822	iron-sulfur transferase activity
LDO37_RS14800	COG1104	cysteine desulfurase activity
LDO37_RS14810	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
LDO37_RS14815	COG0483	inositol monophosphate 1-phosphatase activity
LDO37_RS14820	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LDO37_RS14825	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LDO37_RS14830	COG1862	Preprotein translocase
LDO37_RS14835	COG0343	queuine tRNA-ribosyltransferase activity
LDO37_RS14840	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LDO37_RS14850	COG0517	IMP dehydrogenase activity
LDO37_RS14865	COG0583	DNA-binding transcription factor activity
LDO37_RS14870	COG0450	alkyl hydroperoxide reductase
LDO37_RS14875	COG3142	Participates in the control of copper homeostasis
LDO37_RS14895	COG0704	Plays a role in the regulation of phosphate uptake
LDO37_RS14900	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LDO37_RS14905	COG0581	inorganic phosphate transmembrane transporter activity
LDO37_RS14910	COG0573	inorganic phosphate transmembrane transporter activity
LDO37_RS14915	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
LDO37_RS14920	COG0248	Ppx GppA phosphatase
LDO37_RS14930	COG5002	protein histidine kinase activity
LDO37_RS14935	COG0745	RESPONSE REGULATOR receiver
LDO37_RS14950	COG0826	peptidase U32
LDO37_RS14955	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LDO37_RS14975	COG0848	biopolymer transport protein
LDO37_RS14980	COG0811	peptide transport
LDO37_RS14985	COG0811	peptide transport
LDO37_RS15030	COG0542	response to heat
LDO37_RS15040	COG0564	pseudouridine synthase activity
LDO37_RS15045	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LDO37_RS15050	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LDO37_RS15055	COG0077	Prephenate dehydratase
LDO37_RS15055	COG1605	Chorismate mutase
LDO37_RS15060	COG5001	Diguanylate cyclase
LDO37_RS15065	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
LDO37_RS15070	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
LDO37_RS15080	COG0488	(ABC) transporter
LDO37_RS15090	COG0739	heme binding
LDO37_RS15095	COG0287	Prephenate dehydrogenase
LDO37_RS15095	COG1605	Chorismate mutase
LDO37_RS15100	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LDO37_RS15105	COG3275	phosphorelay sensor kinase activity
LDO37_RS15110	COG3279	Response regulator of the LytR AlgR family
LDO37_RS15120	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
LDO37_RS15125	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
LDO37_RS15140	COG1966	Carbon starvation protein
LDO37_RS15150	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
LDO37_RS15155	COG1047	Peptidyl-prolyl cis-trans
LDO37_RS15160	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LDO37_RS15170	COG0196	riboflavin kinase activity
LDO37_RS15175	COG0728	peptidoglycan biosynthetic process
LDO37_RS15180	COG0268	Binds directly to 16S ribosomal RNA
LDO37_RS15185	COG0640	Transcriptional regulator
LDO37_RS15190	COG0583	DNA-binding transcription factor activity
LDO37_RS15195	COG1283	sodium-dependent phosphate transmembrane transporter activity
LDO37_RS15200	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LDO37_RS15205	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LDO37_RS15210	COG0730	response to heat
LDO37_RS15220	COG0494	nUDIX hydrolase
LDO37_RS15235	COG0667	Aldo Keto reductase
LDO37_RS15245	COG2204	response regulator
LDO37_RS15250	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
LDO37_RS15260	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LDO37_RS15265	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LDO37_RS15270	COG4974	Belongs to the 'phage' integrase family
LDO37_RS15275	COG0716	FMN binding
LDO37_RS15290	COG0513	Belongs to the DEAD box helicase family
LDO37_RS15295	COG1737	Transcriptional regulator
LDO37_RS15305	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
LDO37_RS15310	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LDO37_RS15320	COG3842	ATPase activity
LDO37_RS15325	COG0395	ABC-type sugar transport system, permease component
LDO37_RS15330	COG1175	transmembrane transport
LDO37_RS15335	COG2182	Extracellular solute-binding protein
LDO37_RS15340	COG1940	carbohydrate kinase activity
LDO37_RS15350	COG3022	response to hydroperoxide
LDO37_RS15355	COG1115	amino acid carrier protein
LDO37_RS15370	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LDO37_RS15380	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
LDO37_RS15385	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LDO37_RS15390	COG0083	homoserine kinase activity
LDO37_RS15405	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LDO37_RS15415	COG0745	RESPONSE REGULATOR receiver
LDO37_RS15425	COG0784	Response regulator, receiver
LDO37_RS15425	COG2198	Histidine kinase
LDO37_RS15425	COG5002	protein histidine kinase activity
LDO37_RS15430	COG3706	GGDEF domain
LDO37_RS15430	COG4251	negative regulation of phosphorylation
LDO37_RS15430	COG5001	Diguanylate cyclase
LDO37_RS15430	COG2203	Gaf domain
LDO37_RS15435	COG1242	4 iron, 4 sulfur cluster binding
LDO37_RS15440	COG0069	glutamate synthase activity
LDO37_RS15440	COG0070	glutamate synthase
LDO37_RS15440	COG0067	glutamate synthase
LDO37_RS15450	COG0067	glutamate synthase
LDO37_RS15450	COG0069	glutamate synthase activity
LDO37_RS15450	COG0070	glutamate synthase
LDO37_RS15455	COG0493	'glutamate synthase
LDO37_RS15480	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LDO37_RS15485	COG2860	membrane
LDO37_RS15500	COG0655	NAD(P)H dehydrogenase (quinone) activity
LDO37_RS15510	COG0814	amino acid
LDO37_RS15525	COG1119	ATPase activity
LDO37_RS15530	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LDO37_RS15530	COG1522	sequence-specific DNA binding
LDO37_RS15535	COG2313	pseudouridylate synthase activity
LDO37_RS15555	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LDO37_RS15560	COG0505	Belongs to the CarA family
LDO37_RS15585	COG2963	transposase activity
LDO37_RS15590	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
LDO37_RS15595	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LDO37_RS15600	COG0849	cell division
LDO37_RS15605	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
LDO37_RS15615	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LDO37_RS15620	COG0772	Belongs to the SEDS family
LDO37_RS15625	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LDO37_RS15630	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LDO37_RS15635	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LDO37_RS15645	COG0768	penicillin binding
LDO37_RS15650	COG3116	cell division
LDO37_RS15665	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LDO37_RS15670	COG3107	peptidoglycan biosynthetic process
LDO37_RS15675	COG0792	nuclease activity
LDO37_RS15680	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
LDO37_RS15685	COG2823	Periplasmic or secreted lipoprotein
LDO37_RS15690	COG2969	positive regulation of protein catabolic process
LDO37_RS15695	COG0625	glutathione transferase activity
LDO37_RS15700	COG2857	Cytochrome c1
LDO37_RS15705	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
LDO37_RS15710	COG0723	plastoquinol--plastocyanin reductase activity
LDO37_RS15715	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LDO37_RS15725	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
LDO37_RS15730	COG3105	Protein conserved in bacteria
LDO37_RS15735	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LDO37_RS15740	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LDO37_RS15755	COG3150	esterase
LDO37_RS15765	COG3151	Protein conserved in bacteria
LDO37_RS15770	COG0494	nUDIX hydrolase
LDO37_RS15775	COG1538	Outer membrane efflux protein
LDO37_RS15780	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
LDO37_RS15780	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
LDO37_RS15785	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
LDO37_RS15795	COG3025	triphosphatase activity
LDO37_RS15800	COG1392	Phosphate transport regulator
LDO37_RS15805	COG0306	phosphate transporter
LDO37_RS15810	COG4991	sh3 domain protein
LDO37_RS15820	COG3409	Peptidoglycan-binding domain 1 protein
LDO37_RS15820	COG3267	Type II secretory pathway component ExeA
LDO37_RS15825	COG0617	tRNA 3'-terminal CCA addition
LDO37_RS15840	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LDO37_RS15845	COG0508	dehydrogenase complex catalyzes the overall conversion of
LDO37_RS15850	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
LDO37_RS15855	COG2186	Transcriptional regulator
LDO37_RS15865	COG0157	Belongs to the NadC ModD family
LDO37_RS15875	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LDO37_RS15880	COG1459	type II secretion system
LDO37_RS15895	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
LDO37_RS15900	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
LDO37_RS15905	COG0494	nUDIX hydrolase
LDO37_RS15915	COG0336	Belongs to the RNA methyltransferase TrmD family
LDO37_RS15930	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LDO37_RS15935	COG4137	Cytochrome C assembly protein
LDO37_RS15940	COG4536	flavin adenine dinucleotide binding
LDO37_RS15950	COG1854	S-ribosylhomocysteine lyase activity
LDO37_RS15965	COG0612	Peptidase, M16
LDO37_RS15970	COG1238	metal cluster binding
LDO37_RS15980	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
LDO37_RS15985	COG0511	ligase activity, forming carbon-carbon bonds
LDO37_RS15985	COG5016	pyruvate
LDO37_RS15990	COG3630	sodium ion export across plasma membrane
LDO37_RS16035	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
LDO37_RS16040	COG0527	aspartate kinase activity
LDO37_RS16045	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LDO37_RS16050	COG2137	regulation of response to DNA damage stimulus
LDO37_RS16055	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LDO37_RS16060	COG1546	Belongs to the CinA family
LDO37_RS16065	COG3853	Toxic anion resistance protein (TelA)
LDO37_RS16075	COG2255	four-way junction helicase activity
LDO37_RS16100	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LDO37_RS16115	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
LDO37_RS16120	COG0585	pseudouridine synthase activity
LDO37_RS16130	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
LDO37_RS16135	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
LDO37_RS16150	COG3956	TIGRFAM MazG family protein
LDO37_RS16155	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LDO37_RS16160	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LDO37_RS16165	COG3850	Histidine kinase
LDO37_RS16165	COG2205	protein histidine kinase activity
LDO37_RS16165	COG4999	Histidine kinase
LDO37_RS16165	COG3437	response regulator, receiver
LDO37_RS16190	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
LDO37_RS16195	COG1381	Involved in DNA repair and RecF pathway recombination
LDO37_RS16200	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LDO37_RS16205	COG0571	ribonuclease III activity
LDO37_RS16210	COG0681	Belongs to the peptidase S26 family
LDO37_RS16230	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
LDO37_RS16235	COG1595	DNA-templated transcription, initiation
LDO37_RS16240	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
LDO37_RS16270	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LDO37_RS16275	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LDO37_RS16280	COG3079	Belongs to the UPF0149 family
LDO37_RS16285	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
LDO37_RS16295	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LDO37_RS16305	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LDO37_RS16320	COG1279	arginine transmembrane transporter activity
LDO37_RS16330	COG0668	transmembrane transport
LDO37_RS16335	COG0191	fructose-bisphosphate aldolase activity
LDO37_RS16345	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LDO37_RS16355	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LDO37_RS16360	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LDO37_RS16375	COG2356	endonuclease I
LDO37_RS16380	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LDO37_RS16385	COG0189	ligase activity
LDO37_RS16390	COG1678	Uncharacterized ACR, COG1678
LDO37_RS16395	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LDO37_RS16410	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LDO37_RS16415	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LDO37_RS16420	COG0762	integral membrane protein
LDO37_RS16435	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LDO37_RS16440	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LDO37_RS16445	COG2066	Belongs to the glutaminase family
LDO37_RS16455	COG1194	a g-specific adenine glycosylase
LDO37_RS16465	COG0741	lytic transglycosylase activity
LDO37_RS16555	COG0175	sulfate reduction
LDO37_RS16565	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LDO37_RS16590	COG0582	viral genome integration into host DNA
LDO37_RS16615	COG1715	Restriction endonuclease
LDO37_RS16620	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
LDO37_RS16625	COG0732	type I restriction modification DNA specificity domain
LDO37_RS16630	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
LDO37_RS16685	COG0735	belongs to the Fur family
LDO37_RS16700	COG0432	Pfam Uncharacterised protein family UPF0047
LDO37_RS16710	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LDO37_RS16730	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LDO37_RS16735	COG2965	DNA replication, synthesis of RNA primer
LDO37_RS16740	COG0360	Binds together with S18 to 16S ribosomal RNA
LDO37_RS16750	COG1012	belongs to the aldehyde dehydrogenase family
LDO37_RS16760	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LDO37_RS16790	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LDO37_RS16790	COG2070	2-Nitropropane dioxygenase
LDO37_RS16795	COG2207	Transcriptional regulator
LDO37_RS16800	COG4771	TonB-dependent receptor
LDO37_RS16805	COG1132	(ABC) transporter
LDO37_RS16805	COG2375	cellular response to nickel ion
LDO37_RS16810	COG1132	(ABC) transporter
LDO37_RS16825	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LDO37_RS16825	COG2226	methyltransferase
LDO37_RS16825	COG3433	isochorismatase activity
LDO37_RS16830	COG1021	2,3-dihydroxybenzoate-AMP ligase
LDO37_RS16880	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LDO37_RS16890	COG0583	DNA-binding transcription factor activity
LDO37_RS16900	COG0180	Tryptophanyl-tRNA synthetase
LDO37_RS16905	COG0546	phosphoglycolate phosphatase activity
LDO37_RS16910	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LDO37_RS16915	COG0338	D12 class N6 adenine-specific DNA methyltransferase
LDO37_RS16925	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
LDO37_RS16960	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
LDO37_RS16970	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
LDO37_RS16970	COG0678	peroxiredoxin activity
LDO37_RS16975	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LDO37_RS16990	COG0165	Argininosuccinate lyase
LDO37_RS16990	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
LDO37_RS16995	COG0137	argininosuccinate synthase activity
LDO37_RS17000	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LDO37_RS17005	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
LDO37_RS17010	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LDO37_RS17015	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
LDO37_RS17025	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
LDO37_RS17030	COG0460	homoserine dehydrogenase
LDO37_RS17030	COG0527	aspartate kinase activity
LDO37_RS17035	COG0626	cystathionine gamma-synthase activity
LDO37_RS17040	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
LDO37_RS17045	COG0281	malic enzyme
LDO37_RS17055	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LDO37_RS17060	COG1609	Transcriptional regulator
LDO37_RS17070	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
LDO37_RS17080	COG1575	Belongs to the MenA family. Type 1 subfamily
LDO37_RS17090	COG3074	FtsZ-dependent cytokinesis
LDO37_RS17095	COG1494	fructose-1,6-bisphosphatase
LDO37_RS17110	COG3152	Membrane
LDO37_RS17120	COG0149	triose-phosphate isomerase activity
LDO37_RS17125	COG1414	Transcriptional regulator
LDO37_RS17155	COG1045	serine acetyltransferase
LDO37_RS17160	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
LDO37_RS17165	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
LDO37_RS17170	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LDO37_RS17175	COG2373	Large extracellular alpha-helical protein
LDO37_RS17180	COG4953	penicillin-binding protein 1C
LDO37_RS17190	COG4942	peptidase
LDO37_RS17205	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LDO37_RS17235	COG1216	Glycosyl transferase, family 2
LDO37_RS17240	COG1132	(ABC) transporter
LDO37_RS17275	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LDO37_RS17290	COG1482	cell wall glycoprotein biosynthetic process
LDO37_RS17320	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LDO37_RS17325	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
LDO37_RS17405	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LDO37_RS17415	COG0726	polysaccharide deacetylase
LDO37_RS17420	COG0859	PFAM glycosyl transferase family 9
LDO37_RS17425	COG1519	Transferase
LDO37_RS17445	COG1216	Glycosyl transferase, family 2
LDO37_RS17450	COG3642	lipopolysaccharide core region biosynthetic process
LDO37_RS17455	COG0859	PFAM glycosyl transferase family 9
LDO37_RS17460	COG0463	Glycosyl transferase, family 2
LDO37_RS17465	COG0859	PFAM glycosyl transferase family 9
LDO37_RS17470	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LDO37_RS17475	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LDO37_RS17490	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LDO37_RS17495	COG0227	Belongs to the bacterial ribosomal protein bL28 family
LDO37_RS17500	COG2003	Belongs to the UPF0758 family
LDO37_RS17505	COG1858	cytochrome C peroxidase
LDO37_RS17510	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LDO37_RS17515	COG1309	transcriptional regulator
LDO37_RS17520	COG1560	Kdo2-lipid A biosynthetic process
LDO37_RS17525	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LDO37_RS17530	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
LDO37_RS17535	COG1561	YicC-like family, N-terminal region
LDO37_RS17545	COG0194	GDP metabolic process
LDO37_RS17550	COG1758	RNA polymerase activity
LDO37_RS17555	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LDO37_RS17560	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LDO37_RS17580	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LDO37_RS17590	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LDO37_RS17610	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LDO37_RS17615	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LDO37_RS17620	COG2183	response to ionizing radiation
LDO37_RS17625	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
LDO37_RS17630	COG3161	chorismate lyase activity
LDO37_RS17640	COG0705	Rhomboid family
LDO37_RS17655	COG2177	Part of the ABC transporter FtsEX involved in
LDO37_RS17660	COG2884	Cell division ATP-binding protein ftsE
LDO37_RS17665	COG0552	protein localization to endoplasmic reticulum
LDO37_RS17670	COG0742	ribosomal rna small subunit methyltransferase
LDO37_RS17680	COG2095	MarC family integral membrane protein
LDO37_RS17705	COG3274	enterobacterial common antigen metabolic process
LDO37_RS17710	COG4221	oxidoreductase activity
LDO37_RS17715	COG0583	DNA-binding transcription factor activity
LDO37_RS17720	COG0783	Belongs to the Dps family
LDO37_RS17725	COG1609	Transcriptional regulator
LDO37_RS17730	COG1840	ABC-type Fe3 transport system, periplasmic component
LDO37_RS17740	COG3842	ATPase activity
LDO37_RS17745	COG0483	inositol monophosphate 1-phosphatase activity
LDO37_RS17760	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LDO37_RS17765	COG0640	Transcriptional regulator
LDO37_RS17770	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
LDO37_RS17775	COG1280	lysine exporter protein (LysE YggA)
LDO37_RS17785	COG0561	phosphatase activity
LDO37_RS17800	COG3148	PFAM DTW domain containing protein
LDO37_RS17810	COG2199	diguanylate cyclase activity
LDO37_RS17810	COG2200	EAL domain
LDO37_RS17810	COG3287	FIST C domain
LDO37_RS17815	COG1011	Hydrolase
LDO37_RS17820	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
LDO37_RS17830	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LDO37_RS17835	COG0019	diaminopimelate decarboxylase activity
LDO37_RS17850	COG3072	Adenylate cyclase
LDO37_RS17860	COG1587	Uroporphyrinogen-III synthase
LDO37_RS17865	COG2959	enzyme of heme biosynthesis
LDO37_RS17870	COG3071	HemY protein
LDO37_RS17945	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
LDO37_RS17960	COG3118	belongs to the thioredoxin family
LDO37_RS17970	COG0248	Ppx GppA phosphatase
LDO37_RS17980	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LDO37_RS17985	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
LDO37_RS17995	COG2188	Transcriptional regulator
LDO37_RS18000	COG0673	inositol 2-dehydrogenase activity
LDO37_RS18005	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
LDO37_RS18015	COG0514	ATP-dependent DNA helicase (RecQ)
LDO37_RS18020	COG2962	Rard protein
LDO37_RS18030	COG1280	lysine exporter protein (LysE YggA)
LDO37_RS18035	COG0405	Gamma-glutamyltransferase
LDO37_RS18040	COG0210	DNA helicase
LDO37_RS18050	COG3220	belongs to the UPF0276 family
LDO37_RS18080	COG0006	proline dipeptidase activity
LDO37_RS18090	COG2022	thiamine diphosphate biosynthetic process
LDO37_RS18100	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LDO37_RS18110	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
LDO37_RS18115	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LDO37_RS18160	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LDO37_RS18170	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LDO37_RS18175	COG0408	coproporphyrinogen oxidase activity
LDO37_RS18180	COG0009	L-threonylcarbamoyladenylate synthase
LDO37_RS18185	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LDO37_RS18190	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LDO37_RS18195	COG0551	DNA topoisomerase type I activity
LDO37_RS18200	COG2922	Belongs to the Smg family
LDO37_RS18205	COG0758	DNA mediated transformation
LDO37_RS18210	COG1652	LysM domain
LDO37_RS18215	COG0242	peptide deformylase activity
LDO37_RS18225	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LDO37_RS18225	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LDO37_RS18230	COG0569	domain protein
LDO37_RS18235	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LDO37_RS18240	COG1272	protein, Hemolysin III
LDO37_RS18245	COG4326	sporulation control protein
LDO37_RS18250	COG3084	Protein conserved in bacteria
LDO37_RS18260	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LDO37_RS18265	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LDO37_RS18270	COG0204	Acyl-transferase
LDO37_RS18280	COG0606	chelatase, subunit chli
LDO37_RS18290	COG3978	acetolactate synthase activity
LDO37_RS18295	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LDO37_RS18310	COG0583	DNA-binding transcription factor activity
LDO37_RS18315	COG2814	Major facilitator Superfamily
LDO37_RS18320	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LDO37_RS18325	COG0765	amino acid transport
LDO37_RS18335	COG0355	proton-transporting ATP synthase activity, rotational mechanism
LDO37_RS18345	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LDO37_RS18350	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LDO37_RS18355	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LDO37_RS18370	COG0356	it plays a direct role in the translocation of protons across the membrane
LDO37_RS18375	COG3312	ion transport
LDO37_RS18380	COG1475	DNA binding
LDO37_RS18385	COG1192	Involved in chromosome partitioning
LDO37_RS18390	COG0357	Ribosomal RNA small subunit methyltransferase G
LDO37_RS18395	COG0445	tRNA wobble uridine modification
LDO37_RS18400	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LDO37_RS18410	COG0848	biopolymer transport protein
LDO37_RS18420	COG4783	chaperone-mediated protein folding
LDO37_RS18445	COG3712	iron ion homeostasis
LDO37_RS18450	COG1595	DNA-templated transcription, initiation
LDO37_RS18460	COG0706	membrane insertase activity
LDO37_RS18470	COG0594	ribonuclease P activity
LDO37_RS18475	COG0230	Belongs to the bacterial ribosomal protein bL34 family
LDO37_RS18480	COG1126	abc transporter atp-binding protein
LDO37_RS18505	COG4608	Belongs to the ABC transporter superfamily
LDO37_RS18510	COG0444	Belongs to the ABC transporter superfamily
LDO37_RS18540	COG0789	Transcriptional regulator
LDO37_RS18555	COG2264	protein methyltransferase activity
LDO37_RS18570	COG1028	Short-chain dehydrogenase reductase Sdr
LDO37_RS18590	COG1129	ABC transporter
LDO37_RS18595	COG1172	Belongs to the binding-protein-dependent transport system permease family
LDO37_RS18600	COG1172	Belongs to the binding-protein-dependent transport system permease family
LDO37_RS18625	COG0601	transmembrane transport
LDO37_RS18630	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LDO37_RS18635	COG0444	Belongs to the ABC transporter superfamily
LDO37_RS18640	COG4172	Belongs to the ABC transporter superfamily
LDO37_RS18665	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LDO37_RS18675	COG1028	Short-chain dehydrogenase reductase Sdr
LDO37_RS18720	COG2200	EAL domain
LDO37_RS18720	COG2199	diguanylate cyclase activity
LDO37_RS18730	COG0316	Belongs to the HesB IscA family
LDO37_RS18735	COG0719	Fe-S assembly protein
LDO37_RS18740	COG0396	ATPase activity
LDO37_RS18745	COG0719	Fe-S assembly protein
LDO37_RS18755	COG2166	iron-sulfur cluster assembly
LDO37_RS18770	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LDO37_RS18785	COG1070	Carbohydrate kinase
LDO37_RS18795	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LDO37_RS18800	COG0667	Aldo Keto reductase
LDO37_RS18810	COG1172	Belongs to the binding-protein-dependent transport system permease family
LDO37_RS18815	COG1129	ABC transporter
LDO37_RS18825	COG1454	alcohol dehydrogenase
LDO37_RS18835	COG1414	Transcriptional regulator
LDO37_RS18840	COG3437	response regulator, receiver
LDO37_RS18845	COG4999	Histidine kinase
LDO37_RS18845	COG3850	Histidine kinase
LDO37_RS18845	COG3437	response regulator, receiver
LDO37_RS18845	COG2205	protein histidine kinase activity
LDO37_RS18855	COG2311	Membrane
LDO37_RS18925	COG3706	GGDEF domain
LDO37_RS18930	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LDO37_RS18940	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LDO37_RS18945	COG0800	Aldolase
LDO37_RS18960	COG5001	Diguanylate cyclase
LDO37_RS18965	COG1012	belongs to the aldehyde dehydrogenase family
LDO37_RS18970	COG3284	Transcriptional regulator
LDO37_RS18975	COG0583	DNA-binding transcription factor activity
LDO37_RS18980	COG2814	Major facilitator Superfamily
LDO37_RS18985	COG4251	negative regulation of phosphorylation
LDO37_RS18985	COG5001	Diguanylate cyclase
LDO37_RS18985	COG3706	GGDEF domain
LDO37_RS18985	COG2203	Gaf domain
LDO37_RS19075	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LDO37_RS19090	COG1979	alcohol dehydrogenase
LDO37_RS19095	COG0583	DNA-binding transcription factor activity
LDO37_RS19110	COG4172	Belongs to the ABC transporter superfamily
LDO37_RS19145	COG1012	belongs to the aldehyde dehydrogenase family
LDO37_RS19160	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LDO37_RS19165	COG1012	belongs to the aldehyde dehydrogenase family
LDO37_RS19170	COG3384	dioxygenase
LDO37_RS19200	COG3971	2-oxopent-4-enoate hydratase activity
LDO37_RS19210	COG1960	acyl-CoA dehydrogenase activity
LDO37_RS19230	COG1067	ATP-dependent peptidase activity
LDO37_RS19245	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LDO37_RS19260	COG2814	Major facilitator Superfamily
LDO37_RS19310	COG1012	belongs to the aldehyde dehydrogenase family
LDO37_RS19345	COG0840	transmembrane signaling receptor activity
LDO37_RS19350	COG1846	Transcriptional regulator
LDO37_RS19370	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
LDO37_RS19370	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
LDO37_RS19375	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
LDO37_RS19380	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LDO37_RS19410	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LDO37_RS19415	COG2999	glutathione oxidoreductase activity
LDO37_RS19430	COG1278	Cold shock
LDO37_RS19450	COG4452	Inner membrane protein CreD
LDO37_RS19455	COG2205	protein histidine kinase activity
LDO37_RS19460	COG0745	RESPONSE REGULATOR receiver
LDO37_RS19465	COG0730	response to heat
LDO37_RS19470	COG0280	phosphate acetyltransferase
LDO37_RS19475	COG1414	Transcriptional regulator
LDO37_RS19480	COG2188	Transcriptional regulator
LDO37_RS19490	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LDO37_RS19500	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LDO37_RS19500	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LDO37_RS19505	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LDO37_RS19515	COG2205	protein histidine kinase activity
LDO37_RS19520	COG0745	RESPONSE REGULATOR receiver
LDO37_RS19530	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
LDO37_RS19535	COG0534	Mate efflux family protein
LDO37_RS19540	COG0583	DNA-binding transcription factor activity
LDO37_RS19550	COG2962	Rard protein
LDO37_RS19565	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LDO37_RS19575	COG1012	belongs to the aldehyde dehydrogenase family
LDO37_RS19585	COG0583	DNA-binding transcription factor activity
LDO37_RS19595	COG0583	DNA-binding transcription factor activity
LDO37_RS19605	COG0573	inorganic phosphate transmembrane transporter activity
LDO37_RS19610	COG0581	inorganic phosphate transmembrane transporter activity
LDO37_RS19615	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LDO37_RS19625	COG0395	ABC-type sugar transport system, permease component
LDO37_RS19630	COG1175	transmembrane transport
LDO37_RS19640	COG3842	ATPase activity
LDO37_RS19650	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LDO37_RS19660	COG1028	Short-chain dehydrogenase reductase Sdr
LDO37_RS19665	COG1609	Transcriptional regulator
LDO37_RS19705	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LDO37_RS19710	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LDO37_RS19720	COG0789	Transcriptional regulator
LDO37_RS19745	COG2814	Major facilitator Superfamily
LDO37_RS19750	COG0583	DNA-binding transcription factor activity
LDO37_RS19755	COG0523	cobalamin synthesis protein
LDO37_RS19770	COG3485	protocatechuate 3,4-dioxygenase
LDO37_RS19780	COG0725	ABC transporter, periplasmic molybdate-binding protein
LDO37_RS19785	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
LDO37_RS19810	COG1349	DNA-binding transcription factor activity
LDO37_RS19835	COG0612	Peptidase, M16
LDO37_RS19855	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LDO37_RS19890	COG3135	benzoate transporter
LDO37_RS19895	COG1396	sequence-specific DNA binding
LDO37_RS19935	COG2205	protein histidine kinase activity
LDO37_RS19945	COG1404	Belongs to the peptidase S8 family
LDO37_RS19950	COG0583	DNA-binding transcription factor activity
LDO37_RS20015	COG0215	cysteine-tRNA ligase activity
LDO37_RS20020	COG2162	N-hydroxyarylamine O-acetyltransferase activity
LDO37_RS20030	COG1404	Belongs to the peptidase S8 family
LDO37_RS20035	COG0443	Heat shock 70 kDa protein
LDO37_RS20050	COG2207	Transcriptional regulator
LDO37_RS20075	COG2132	Multicopper oxidase
LDO37_RS20080	COG3122	Protein conserved in bacteria
LDO37_RS20105	COG0402	S-adenosylhomocysteine deaminase activity
LDO37_RS20110	COG2197	response regulator
LDO37_RS20125	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
LDO37_RS20125	COG2755	lipolytic protein G-D-S-L family
LDO37_RS20140	COG0473	3-isopropylmalate dehydrogenase activity
LDO37_RS20145	COG0583	DNA-binding transcription factor activity
LDO37_RS20165	COG0789	Transcriptional regulator
LDO37_RS20185	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LDO37_RS20200	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LDO37_RS20215	COG2197	response regulator
LDO37_RS20230	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LDO37_RS20235	COG4585	Histidine kinase
LDO37_RS20265	COG3501	Rhs element vgr protein
LDO37_RS20320	COG3209	COG3209 Rhs family protein
LDO37_RS20335	COG3501	Rhs element vgr protein
LDO37_RS20390	COG3501	Rhs element vgr protein
LDO37_RS20450	COG3829	transcription factor binding
LDO37_RS20480	COG4943	cyclic-guanylate-specific phosphodiesterase activity
LDO37_RS20525	COG1215	transferase activity, transferring glycosyl groups
LDO37_RS20535	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
LDO37_RS20560	COG1215	transferase activity, transferring glycosyl groups
LDO37_RS20570	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
LDO37_RS20580	COG1073	alpha beta
LDO37_RS20595	COG1278	Cold shock
LDO37_RS20620	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LDO37_RS20655	COG3852	Histidine kinase
LDO37_RS20660	COG0583	DNA-binding transcription factor activity
LDO37_RS20680	COG2249	NAD(P)H dehydrogenase (quinone) activity
LDO37_RS20685	COG1357	PFAM Pentapeptide repeats (8 copies)
LDO37_RS20690	COG1028	Short-chain dehydrogenase reductase Sdr
LDO37_RS20695	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
LDO37_RS20700	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
LDO37_RS20710	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LDO37_RS20715	COG2186	Transcriptional regulator
LDO37_RS20765	COG2274	protein secretion by the type I secretion system
LDO37_RS20770	COG0438	transferase activity, transferring glycosyl groups
LDO37_RS20780	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LDO37_RS20795	COG0183	Belongs to the thiolase family
LDO37_RS20800	COG3214	Protein conserved in bacteria
LDO37_RS20805	COG0583	DNA-binding transcription factor activity
LDO37_RS20820	COG0625	glutathione transferase activity
LDO37_RS20830	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
LDO37_RS20860	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LDO37_RS20890	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LDO37_RS20895	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
LDO37_RS20930	COG0024	Methionine aminopeptidase
LDO37_RS20970	COG0058	SHG alpha-glucan phosphorylase activity
LDO37_RS20975	COG1640	4-alpha-glucanotransferase
LDO37_RS20980	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LDO37_RS20985	COG0840	transmembrane signaling receptor activity
LDO37_RS21020	COG3123	guanosine phosphorylase activity
LDO37_RS21030	COG0697	spore germination
LDO37_RS21040	COG5001	Diguanylate cyclase
LDO37_RS21075	COG1054	Belongs to the UPF0176 family
LDO37_RS21105	COG1794	racemase activity, acting on amino acids and derivatives
LDO37_RS21120	COG2329	Antibiotic biosynthesis monooxygenase
LDO37_RS21125	COG0454	-acetyltransferase
LDO37_RS21135	COG0366	Alpha amylase catalytic
LDO37_RS21155	COG3706	GGDEF domain
LDO37_RS21160	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
LDO37_RS21165	COG2204	response regulator
LDO37_RS21195	COG0579	oxidoreductase
LDO37_RS21205	COG0531	amino acid
LDO37_RS21210	COG1522	sequence-specific DNA binding
LDO37_RS21215	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LDO37_RS21240	COG0402	S-adenosylhomocysteine deaminase activity
LDO37_RS21325	COG2267	carboxylic ester hydrolase activity
LDO37_RS21340	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LDO37_RS21400	COG2186	Transcriptional regulator
LDO37_RS21405	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
LDO37_RS21410	COG1309	transcriptional regulator
LDO37_RS21430	COG4266	Belongs to the allantoicase family
LDO37_RS21455	COG1902	pentaerythritol trinitrate reductase activity
LDO37_RS21490	COG5380	lipid catabolic process
LDO37_RS21495	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
LDO37_RS21510	COG0798	PFAM Bile acid sodium symporter
LDO37_RS21520	COG1846	Transcriptional regulator
LDO37_RS21565	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LDO37_RS21570	COG2188	Transcriptional regulator
LDO37_RS21585	COG0395	ABC-type sugar transport system, permease component
LDO37_RS21590	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
LDO37_RS21595	COG3842	ATPase activity
LDO37_RS21600	COG1741	Belongs to the pirin family
LDO37_RS21610	COG0778	Nitroreductase
LDO37_RS21615	COG4191	Histidine kinase
LDO37_RS21645	COG1629	transport
LDO37_RS21645	COG4774	siderophore transport
LDO37_RS21655	COG1021	2,3-dihydroxybenzoate-AMP ligase
LDO37_RS21660	COG0287	Prephenate dehydrogenase
LDO37_RS21660	COG1605	Chorismate mutase
LDO37_RS21675	COG1021	2,3-dihydroxybenzoate-AMP ligase
LDO37_RS21680	COG1169	isochorismate synthase
LDO37_RS21685	COG1028	Short-chain dehydrogenase reductase Sdr
LDO37_RS21690	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LDO37_RS21695	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
LDO37_RS21695	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LDO37_RS21700	COG4592	Periplasmic binding protein
LDO37_RS21705	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LDO37_RS21710	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LDO37_RS21720	COG1120	ATPase activity
LDO37_RS21730	COG4667	esterase of the alpha-beta hydrolase superfamily
LDO37_RS21735	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LDO37_RS21765	COG3448	diguanylate cyclase activity
LDO37_RS21765	COG4175	Glycine betaine
LDO37_RS21780	COG2175	clavaminate synthase activity
LDO37_RS21785	COG1280	lysine exporter protein (LysE YggA)
LDO37_RS21795	COG0659	secondary active sulfate transmembrane transporter activity
LDO37_RS21800	COG1085	galactose-1-phosphate uridylyltransferase
LDO37_RS21805	COG1028	Short-chain dehydrogenase reductase Sdr
LDO37_RS21825	COG1028	Short-chain dehydrogenase reductase Sdr
LDO37_RS21845	COG4948	Mandelate Racemase Muconate Lactonizing
LDO37_RS21850	COG2186	Transcriptional regulator
LDO37_RS21890	COG5492	domain, Protein
LDO37_RS21920	COG4964	Belongs to the GSP D family
LDO37_RS21970	COG2885	chlorophyll binding
LDO37_RS21980	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
LDO37_RS21990	COG0561	phosphatase activity
LDO37_RS22005	COG3119	arylsulfatase activity
LDO37_RS22010	COG3119	arylsulfatase activity
LDO37_RS22015	COG0641	radical SAM
LDO37_RS22040	COG0488	(ABC) transporter
LDO37_RS22060	COG0604	alcohol dehydrogenase
LDO37_RS22060	COG1028	Short-chain dehydrogenase reductase Sdr
LDO37_RS22060	COG3321	synthase
LDO37_RS22095	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LDO37_RS22100	COG1012	belongs to the aldehyde dehydrogenase family
LDO37_RS22105	COG1984	allophanate hydrolase subunit 2
LDO37_RS22110	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
LDO37_RS22115	COG0439	Biotin carboxylase
LDO37_RS22130	COG4214	carbohydrate transport
LDO37_RS22135	COG1129	ABC transporter
LDO37_RS22140	COG1879	ABC-type sugar transport system periplasmic component
LDO37_RS22145	COG0583	DNA-binding transcription factor activity
LDO37_RS22150	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
LDO37_RS22155	COG0574	Belongs to the PEP-utilizing enzyme family
LDO37_RS22155	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LDO37_RS22165	COG1028	Short-chain dehydrogenase reductase Sdr
LDO37_RS22180	COG1172	Belongs to the binding-protein-dependent transport system permease family
LDO37_RS22190	COG4948	Mandelate Racemase Muconate Lactonizing
LDO37_RS22225	COG1122	ATPase activity
LDO37_RS22230	COG4720	Psort location CytoplasmicMembrane, score
LDO37_RS22245	COG1011	Hydrolase
LDO37_RS22260	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LDO37_RS22265	COG4605	iron ion homeostasis
LDO37_RS22270	COG4604	ABC transporter, ATP-binding protein
LDO37_RS22275	COG2375	cellular response to nickel ion
LDO37_RS22290	COG4771	TonB-dependent receptor
LDO37_RS22295	COG4607	ABC-type enterochelin transport system periplasmic component
LDO37_RS22300	COG0110	maltose O-acetyltransferase activity
LDO37_RS22310	COG4681	YaeQ
LDO37_RS22320	COG2204	response regulator
LDO37_RS22325	COG4191	Histidine kinase
LDO37_RS22335	COG2211	Major facilitator Superfamily
LDO37_RS22340	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LDO37_RS22355	COG0784	Response regulator, receiver
LDO37_RS22355	COG3437	response regulator, receiver
LDO37_RS22360	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LDO37_RS22365	COG0814	amino acid
LDO37_RS22370	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
LDO37_RS22375	COG0513	Belongs to the DEAD box helicase family
LDO37_RS22380	COG2067	long-chain fatty acid transport protein
LDO37_RS22390	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
LDO37_RS22400	COG0714	Associated with various cellular activities
LDO37_RS22405	COG2425	protein containing a von Willebrand factor type A (vWA) domain
LDO37_RS22425	COG0366	Alpha amylase catalytic
LDO37_RS22430	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LDO37_RS22440	COG2116	formate transmembrane transporter activity
LDO37_RS22445	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LDO37_RS22445	COG1648	precorrin-2 dehydrogenase activity
LDO37_RS22455	COG0789	Transcriptional regulator
LDO37_RS22480	COG1120	ATPase activity
LDO37_RS22485	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LDO37_RS22490	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LDO37_RS22495	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
LDO37_RS22500	COG3530	Putative quorum-sensing-regulated virulence factor
LDO37_RS22540	COG2015	COG2015, Alkyl sulfatase and related hydrolases
LDO37_RS22545	COG0583	DNA-binding transcription factor activity
LDO37_RS22555	COG4934	collagen metabolic process
LDO37_RS22560	COG0789	Transcriptional regulator
LDO37_RS22575	COG0513	Belongs to the DEAD box helicase family
LDO37_RS22595	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LDO37_RS22600	COG1940	carbohydrate kinase activity
LDO37_RS22605	COG1621	beta-fructofuranosidase activity
LDO37_RS22625	COG0572	uridine kinase
LDO37_RS22635	COG1172	Belongs to the binding-protein-dependent transport system permease family
LDO37_RS22640	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LDO37_RS22650	COG4589	Belongs to the CDS family
LDO37_RS22660	COG0564	pseudouridine synthase activity
LDO37_RS22690	COG1609	Transcriptional regulator
LDO37_RS22695	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LDO37_RS22700	COG3265	gluconokinase activity
LDO37_RS22715	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
LDO37_RS22720	COG4191	Histidine kinase
LDO37_RS22720	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LDO37_RS22730	COG2354	Protein conserved in bacteria
LDO37_RS22740	COG1879	ABC-type sugar transport system periplasmic component
LDO37_RS22750	COG4214	carbohydrate transport
LDO37_RS22760	COG1012	belongs to the aldehyde dehydrogenase family
LDO37_RS22765	COG3734	2-keto-3-deoxy-galactonokinase
LDO37_RS22770	COG0800	Aldolase
LDO37_RS22775	COG4948	Mandelate Racemase Muconate Lactonizing
LDO37_RS22820	COG3338	carbonate dehydratase activity
LDO37_RS22835	COG1879	ABC-type sugar transport system periplasmic component
LDO37_RS22840	COG1129	ABC transporter
LDO37_RS22845	COG1172	Belongs to the binding-protein-dependent transport system permease family
LDO37_RS22850	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LDO37_RS22855	COG1349	DNA-binding transcription factor activity
LDO37_RS22860	COG5001	Diguanylate cyclase
LDO37_RS22860	COG5002	protein histidine kinase activity
LDO37_RS22860	COG3447	MASE1 domain protein
LDO37_RS22870	COG2814	Major facilitator Superfamily
LDO37_RS22880	COG5002	protein histidine kinase activity
LDO37_RS22895	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LDO37_RS22900	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LDO37_RS22910	COG5001	Diguanylate cyclase
LDO37_RS22915	COG2897	thiosulfate sulfurtransferase activity
LDO37_RS22940	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LDO37_RS22950	COG0302	gtp cyclohydrolase
LDO37_RS22955	COG0840	transmembrane signaling receptor activity
LDO37_RS22960	COG0545	Peptidyl-prolyl cis-trans isomerase
LDO37_RS22970	COG2885	chlorophyll binding
LDO37_RS22975	COG2759	Belongs to the formate--tetrahydrofolate ligase family
LDO37_RS22980	COG0668	transmembrane transport
LDO37_RS23000	COG1765	OsmC-like protein
LDO37_RS23030	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LDO37_RS23035	COG5654	RES domain protein
LDO37_RS23055	COG0745	RESPONSE REGULATOR receiver
LDO37_RS23070	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LDO37_RS23085	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
LDO37_RS23090	COG0513	Belongs to the DEAD box helicase family
LDO37_RS23095	COG0625	glutathione transferase activity
LDO37_RS23105	COG0840	transmembrane signaling receptor activity
LDO37_RS23125	COG2824	Alkylphosphonate utilization operon protein PhnA
LDO37_RS23130	COG2267	carboxylic ester hydrolase activity
LDO37_RS23135	COG2067	long-chain fatty acid transport protein
LDO37_RS23145	COG2050	protein possibly involved in aromatic compounds catabolism
LDO37_RS23155	COG4533	DNA binding
LDO37_RS23180	COG0747	negative chemotaxis
LDO37_RS23185	COG0444	Belongs to the ABC transporter superfamily
LDO37_RS23190	COG4608	Belongs to the ABC transporter superfamily
LDO37_RS23195	COG0601	transmembrane transport
LDO37_RS23200	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LDO37_RS23245	COG3118	belongs to the thioredoxin family
LDO37_RS23255	COG4191	Histidine kinase
LDO37_RS23265	COG2271	Major facilitator Superfamily
LDO37_RS23270	COG0469	pyruvate kinase activity
LDO37_RS23275	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LDO37_RS23280	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LDO37_RS23300	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
LDO37_RS23305	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LDO37_RS23310	COG4206	TonB-dependent receptor
LDO37_RS23330	COG0583	DNA-binding transcription factor activity
LDO37_RS23335	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LDO37_RS23335	COG1042	CoA-binding domain protein
LDO37_RS23335	COG0045	succinate-CoA ligase (ADP-forming) activity
LDO37_RS23345	COG1181	Belongs to the D-alanine--D-alanine ligase family
LDO37_RS23360	COG0023	Translation Initiation Factor
LDO37_RS23370	COG3140	Belongs to the UPF0181 family
LDO37_RS23385	COG0745	RESPONSE REGULATOR receiver
LDO37_RS23395	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
LDO37_RS23400	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
LDO37_RS23425	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
LDO37_RS23430	COG5001	Diguanylate cyclase
LDO37_RS23430	COG4251	negative regulation of phosphorylation
LDO37_RS23430	COG3706	GGDEF domain
LDO37_RS23430	COG2203	Gaf domain
LDO37_RS23440	COG2885	chlorophyll binding
LDO37_RS23445	COG0840	transmembrane signaling receptor activity
LDO37_RS23460	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
LDO37_RS23465	COG4149	molybdate abc transporter
LDO37_RS23470	COG1492	cobalamin metabolic process
LDO37_RS23485	COG4067	protein conserved in archaea
LDO37_RS23485	COG0189	ligase activity
LDO37_RS23495	COG0602	queuosine metabolic process
LDO37_RS23500	COG1328	CTP reductase activity
LDO37_RS23520	COG0584	glycerophosphoryl diester phosphodiesterase
LDO37_RS23530	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
LDO37_RS23535	COG3639	organic phosphonate transmembrane transporter activity
LDO37_RS23540	COG3639	organic phosphonate transmembrane transporter activity
LDO37_RS23545	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
LDO37_RS23550	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
LDO37_RS23555	COG4181	ATPase activity
LDO37_RS23565	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
LDO37_RS23570	COG1716	ATPase activity
LDO37_RS23570	COG5001	Diguanylate cyclase
LDO37_RS23580	COG0737	Belongs to the 5'-nucleotidase family
LDO37_RS23585	COG3593	DNA synthesis involved in DNA repair
LDO37_RS23595	COG0583	DNA-binding transcription factor activity
LDO37_RS23600	COG2116	formate transmembrane transporter activity
LDO37_RS23605	COG2353	YceI-like domain
LDO37_RS23610	COG3038	cytochrome b561
LDO37_RS23620	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LDO37_RS23640	COG2200	EAL domain
LDO37_RS23660	COG1129	ABC transporter
LDO37_RS23665	COG1172	Belongs to the binding-protein-dependent transport system permease family
LDO37_RS23670	COG1172	Belongs to the binding-protein-dependent transport system permease family
LDO37_RS23675	COG1879	ABC-type sugar transport system periplasmic component
LDO37_RS23685	COG0459	protein refolding
LDO37_RS23690	COG0508	dehydrogenase complex catalyzes the overall conversion of
LDO37_RS23695	COG1012	belongs to the aldehyde dehydrogenase family
LDO37_RS23700	COG0022	dehydrogenase e1 component
LDO37_RS23705	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LDO37_RS23715	COG1609	Transcriptional regulator
LDO37_RS23725	COG2199	diguanylate cyclase activity
LDO37_RS23725	COG2200	EAL domain
LDO37_RS23725	COG2203	Gaf domain
LDO37_RS23730	COG0523	cobalamin synthesis protein
LDO37_RS23740	COG0156	8-amino-7-oxononanoate synthase activity
LDO37_RS23745	COG0784	Response regulator, receiver
LDO37_RS23745	COG2205	protein histidine kinase activity
LDO37_RS23750	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LDO37_RS23755	COG5001	Diguanylate cyclase
LDO37_RS23755	COG3300	MHYT domain
LDO37_RS23770	COG2154	pterin-4-alpha-carbinolamine dehydratase
LDO37_RS23775	COG0456	acetyltransferase
LDO37_RS23780	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LDO37_RS23785	COG0662	Cupin 2, conserved barrel domain protein
LDO37_RS23790	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
LDO37_RS23830	COG0516	GMP reductase activity
LDO37_RS23835	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LDO37_RS23855	COG2199	diguanylate cyclase activity
LDO37_RS23875	COG2198	Histidine kinase
LDO37_RS23875	COG0784	Response regulator, receiver
LDO37_RS23875	COG2205	protein histidine kinase activity
LDO37_RS23880	COG1879	ABC-type sugar transport system periplasmic component
LDO37_RS23885	COG1803	Methylglyoxal synthase
LDO37_RS23905	COG0210	DNA helicase
LDO37_RS23910	COG1289	transmembrane transporter activity
LDO37_RS23925	COG0861	Integral membrane protein TerC family
LDO37_RS23940	COG1028	Short-chain dehydrogenase reductase Sdr
LDO37_RS23960	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
LDO37_RS23965	COG1063	alcohol dehydrogenase
LDO37_RS23970	COG0156	8-amino-7-oxononanoate synthase activity
LDO37_RS23985	COG0583	DNA-binding transcription factor activity
LDO37_RS24005	COG5001	Diguanylate cyclase
LDO37_RS24010	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
LDO37_RS24015	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
LDO37_RS24045	COG0406	alpha-ribazole phosphatase activity
LDO37_RS24050	COG4191	Histidine kinase
LDO37_RS24065	COG4397	Mu-like prophage major head subunit gpT
LDO37_RS24135	COG2197	response regulator
LDO37_RS24140	COG3850	Histidine kinase
LDO37_RS24145	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
LDO37_RS24145	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LDO37_RS24185	COG0183	Belongs to the thiolase family
LDO37_RS24200	COG2827	Endonuclease containing a URI domain
LDO37_RS24205	COG3132	Protein of unknown function, DUF480
LDO37_RS24210	COG2926	Belongs to the UPF0265 family
LDO37_RS24225	COG0584	glycerophosphoryl diester phosphodiesterase
LDO37_RS24255	COG0784	Response regulator, receiver
LDO37_RS24255	COG2205	protein histidine kinase activity
LDO37_RS24265	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
LDO37_RS24275	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
LDO37_RS24280	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LDO37_RS24285	COG0784	Response regulator, receiver
LDO37_RS24285	COG0835	chemotaxis
LDO37_RS24290	COG1454	alcohol dehydrogenase
LDO37_RS24330	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LDO37_RS24340	COG0633	Ferredoxin
LDO37_RS24340	COG3217	Mosc domain protein beta barrel domain protein
LDO37_RS24340	COG0633	Ferredoxin
LDO37_RS24340	COG3217	Mosc domain protein beta barrel domain protein
LDO37_RS24345	COG0418	dihydroorotase activity
LDO37_RS24355	COG1122	ATPase activity
LDO37_RS24360	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LDO37_RS24365	COG1268	BioY protein
LDO37_RS24380	COG3706	GGDEF domain
LDO37_RS24420	COG0840	transmembrane signaling receptor activity
LDO37_RS24435	COG1609	Transcriptional regulator
LDO37_RS24445	COG1105	Belongs to the carbohydrate kinase PfkB family
LDO37_RS24450	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
LDO37_RS24450	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LDO37_RS24450	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LDO37_RS24455	COG3479	Phenolic acid decarboxylase
LDO37_RS24470	COG0404	The glycine cleavage system catalyzes the degradation of glycine
LDO37_RS24480	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LDO37_RS24485	COG0509	glycine decarboxylation via glycine cleavage system
LDO37_RS24555	COG1917	Cupin 2, conserved barrel domain protein
LDO37_RS24555	COG4977	sequence-specific DNA binding
LDO37_RS24585	COG4771	TonB-dependent receptor
LDO37_RS24590	COG2382	esterase
LDO37_RS24595	COG2130	NADP-dependent
LDO37_RS24635	COG1620	l-lactate permease
LDO37_RS24640	COG1304	FMN binding
LDO37_RS24665	COG1247	-acetyltransferase
LDO37_RS24670	COG0494	nUDIX hydrolase
LDO37_RS24700	COG2818	Glycosylase
LDO37_RS24715	COG0456	acetyltransferase
LDO37_RS24720	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LDO37_RS24735	COG1653	transport
LDO37_RS24745	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LDO37_RS24750	COG3279	Response regulator of the LytR AlgR family
LDO37_RS24755	COG3275	phosphorelay sensor kinase activity
LDO37_RS24775	COG0577	efflux transmembrane transporter activity
LDO37_RS24775	COG1136	(ABC) transporter
LDO37_RS24800	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
LDO37_RS24810	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
LDO37_RS24810	COG2755	lipolytic protein G-D-S-L family
LDO37_RS24850	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LDO37_RS24850	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LDO37_RS24870	COG0673	inositol 2-dehydrogenase activity
LDO37_RS24875	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LDO37_RS24895	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
LDO37_RS24900	COG0840	transmembrane signaling receptor activity
LDO37_RS24915	COG4166	transmembrane transport
LDO37_RS24920	COG4174	ABC transporter (Permease)
LDO37_RS24925	COG4239	(ABC) transporter, permease
LDO37_RS24930	COG4172	Belongs to the ABC transporter superfamily
LDO37_RS24940	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
LDO37_RS24950	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LDO37_RS24955	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LDO37_RS24960	COG1609	Transcriptional regulator
LDO37_RS25040	COG2017	converts alpha-aldose to the beta-anomer
LDO37_RS25045	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LDO37_RS25050	COG1085	galactose-1-phosphate uridylyltransferase
LDO37_RS25055	COG3250	beta-galactosidase activity
LDO37_RS25065	COG0395	ABC-type sugar transport system, permease component
LDO37_RS25070	COG1175	transmembrane transport
LDO37_RS25165	COG0346	lactoylglutathione lyase activity
LDO37_RS25175	COG0346	lactoylglutathione lyase activity
LDO37_RS25190	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
LDO37_RS25195	COG3842	ATPase activity
LDO37_RS25215	COG1609	Transcriptional regulator
LDO37_RS25230	COG0747	negative chemotaxis
LDO37_RS25240	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LDO37_RS25245	COG0444	Belongs to the ABC transporter superfamily
LDO37_RS25250	COG4608	Belongs to the ABC transporter superfamily
LDO37_RS25275	COG1247	-acetyltransferase
LDO37_RS25280	COG0730	response to heat
LDO37_RS25410	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
LDO37_RS25430	COG0527	aspartate kinase activity
LDO37_RS25440	COG3706	GGDEF domain
LDO37_RS25450	COG0840	transmembrane signaling receptor activity
LDO37_RS25660	COG5377	YqaJ viral recombinase family
LDO37_RS25675	COG0582	viral genome integration into host DNA
LDO37_RS25925	COG0179	Fumarylacetoacetate (FAA) hydrolase
LDO37_RS25960	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
LDO37_RS25965	COG0753	catalase activity
LDO37_RS25975	COG5001	Diguanylate cyclase
LDO37_RS25975	COG3300	MHYT domain
LDO37_RS25980	COG1802	Transcriptional regulator
LDO37_RS25985	COG4608	Belongs to the ABC transporter superfamily
LDO37_RS25990	COG0444	Belongs to the ABC transporter superfamily
LDO37_RS25995	COG0601	transmembrane transport
LDO37_RS26000	COG0747	negative chemotaxis
LDO37_RS26055	COG3046	protein related to deoxyribodipyrimidine photolyase
LDO37_RS26080	COG4628	conserved protein (DUF2132)
LDO37_RS26095	COG0251	oxidation-reduction process
LDO37_RS26105	COG0069	glutamate synthase activity
LDO37_RS26135	COG0456	acetyltransferase
LDO37_RS26145	COG1653	transport
LDO37_RS26165	COG3842	ATPase activity
LDO37_RS26180	COG0363	glucosamine-6-phosphate deaminase activity
LDO37_RS26190	COG0513	Belongs to the DEAD box helicase family
LDO37_RS26205	COG1349	DNA-binding transcription factor activity
LDO37_RS26210	COG1349	DNA-binding transcription factor activity
LDO37_RS26220	COG2222	sugar isomerase
LDO37_RS26225	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LDO37_RS26235	COG3716	PTS system mannose fructose sorbose family IID component
LDO37_RS26240	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
LDO37_RS26270	COG0588	phosphoglycerate mutase activity
LDO37_RS26275	COG0640	Transcriptional regulator
LDO37_RS26295	COG0583	DNA-binding transcription factor activity
LDO37_RS26300	COG2124	cytochrome p450
LDO37_RS26310	COG2226	methyltransferase
LDO37_RS26320	COG2501	S4 domain
LDO37_RS26330	COG1280	lysine exporter protein (LysE YggA)
LDO37_RS26355	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
LDO37_RS26380	COG1132	(ABC) transporter
LDO37_RS26400	COG1522	sequence-specific DNA binding
LDO37_RS26405	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
LDO37_RS26420	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
LDO37_RS26425	COG3036	rescue of stalled ribosome
LDO37_RS26455	COG0179	Fumarylacetoacetate (FAA) hydrolase
LDO37_RS26460	COG1846	Transcriptional regulator
LDO37_RS26465	COG0419	ATPase involved in DNA repair
LDO37_RS26470	COG0420	3'-5' exonuclease activity
LDO37_RS26485	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LDO37_RS26525	COG0438	transferase activity, transferring glycosyl groups
LDO37_RS26535	COG5039	Polysaccharide pyruvyl transferase
LDO37_RS26540	COG1216	Glycosyl transferase, family 2
LDO37_RS26540	COG0463	Glycosyl transferase, family 2
LDO37_RS26560	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LDO37_RS26565	COG2197	response regulator
LDO37_RS26580	COG3833	ABC-type maltose transport systems, permease component
LDO37_RS26585	COG1175	transmembrane transport
LDO37_RS26595	COG3842	ATPase activity
LDO37_RS26615	COG0840	transmembrane signaling receptor activity
LDO37_RS26620	COG0714	Associated with various cellular activities
LDO37_RS26640	COG2304	oxidoreductase activity
LDO37_RS26650	COG5002	protein histidine kinase activity
LDO37_RS26650	COG3850	Histidine kinase
LDO37_RS26655	COG0745	RESPONSE REGULATOR receiver
LDO37_RS26660	COG4191	Histidine kinase
LDO37_RS26660	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LDO37_RS26665	COG3437	response regulator, receiver
LDO37_RS26665	COG0784	Response regulator, receiver
LDO37_RS26675	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LDO37_RS26685	COG0109	protoheme IX farnesyltransferase activity
LDO37_RS26690	COG1612	heme a metabolic process
LDO37_RS26715	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
LDO37_RS26720	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LDO37_RS26725	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LDO37_RS26730	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LDO37_RS26740	COG0560	Phosphoserine phosphatase
LDO37_RS26745	COG2197	response regulator
LDO37_RS26755	COG0318	PFAM AMP-dependent synthetase and ligase
LDO37_RS26775	COG2202	Pas domain
LDO37_RS26775	COG2205	protein histidine kinase activity
LDO37_RS26780	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LDO37_RS26785	COG1283	sodium-dependent phosphate transmembrane transporter activity
LDO37_RS26790	COG1126	abc transporter atp-binding protein
LDO37_RS26795	COG0765	amino acid transport
LDO37_RS26800	COG4597	amino acid ABC transporter
LDO37_RS26805	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LDO37_RS26820	COG3842	ATPase activity
LDO37_RS26835	COG1176	ABC-type spermidine putrescine transport system, permease component I
LDO37_RS26900	COG4172	Belongs to the ABC transporter superfamily
LDO37_RS26920	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LDO37_RS26945	COG0346	lactoylglutathione lyase activity
LDO37_RS26950	COG4326	sporulation control protein
LDO37_RS26980	COG0456	acetyltransferase
LDO37_RS27020	COG0583	DNA-binding transcription factor activity
LDO37_RS27025	COG2814	Major facilitator Superfamily
LDO37_RS27045	COG1175	transmembrane transport
LDO37_RS27055	COG1609	Transcriptional regulator
LDO37_RS27065	COG1335	isochorismatase
LDO37_RS27070	COG2249	NAD(P)H dehydrogenase (quinone) activity
LDO37_RS27080	COG1917	Cupin 2, conserved barrel domain protein
LDO37_RS27080	COG4977	sequence-specific DNA binding
LDO37_RS27090	COG0583	DNA-binding transcription factor activity
LDO37_RS27105	COG0583	DNA-binding transcription factor activity
LDO37_RS27110	COG1414	Transcriptional regulator
LDO37_RS27120	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LDO37_RS27125	COG0601	transmembrane transport
LDO37_RS27135	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LDO37_RS27155	COG0515	serine threonine protein kinase
LDO37_RS27155	COG2815	serine threonine protein kinase
LDO37_RS27200	COG1181	Belongs to the D-alanine--D-alanine ligase family
LDO37_RS27275	COG3284	Transcriptional regulator
LDO37_RS27280	COG3842	ATPase activity
LDO37_RS27285	COG3842	ATPase activity
LDO37_RS27295	COG0395	ABC-type sugar transport system, permease component
LDO37_RS27330	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LDO37_RS27390	COG1940	carbohydrate kinase activity
LDO37_RS27400	COG3842	ATPase activity
LDO37_RS27415	COG0076	glutamate decarboxylase activity
LDO37_RS27425	COG4191	Histidine kinase
LDO37_RS27425	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LDO37_RS27435	COG3437	response regulator, receiver
LDO37_RS27435	COG0784	Response regulator, receiver
LDO37_RS27460	COG1770	oligopeptidase
LDO37_RS27475	COG0395	ABC-type sugar transport system, permease component
LDO37_RS27480	COG2723	6-phospho-beta-galactosidase activity
LDO37_RS27485	COG3842	ATPase activity
LDO37_RS27490	COG1609	Transcriptional regulator
LDO37_RS27505	COG0513	Belongs to the DEAD box helicase family
LDO37_RS27515	COG1388	LysM domain
LDO37_RS27515	COG1376	ErfK ybiS ycfS ynhG family protein
LDO37_RS27520	COG0415	Belongs to the DNA photolyase family
LDO37_RS27525	COG0789	Transcriptional regulator
LDO37_RS27530	COG3272	Protein of unknown function (DUF1722)
LDO37_RS27545	COG4214	carbohydrate transport
LDO37_RS27560	COG1609	Transcriptional regulator
LDO37_RS27565	COG0813	purine-nucleoside phosphorylase activity
LDO37_RS27605	COG3706	GGDEF domain
LDO37_RS27610	COG0693	protein deglycase activity
LDO37_RS27625	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
LDO37_RS27635	COG1505	serine-type exopeptidase activity
LDO37_RS27655	COG3314	Sporulation integral membrane protein YlbJ
LDO37_RS27690	COG1595	DNA-templated transcription, initiation
LDO37_RS27700	COG1505	serine-type exopeptidase activity
LDO37_RS27705	COG1737	Transcriptional regulator
LDO37_RS27715	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LDO37_RS27725	COG2140	Oxalate decarboxylase
LDO37_RS27730	COG1175	transmembrane transport
LDO37_RS27735	COG0395	ABC-type sugar transport system, permease component
LDO37_RS27745	COG3842	ATPase activity
LDO37_RS27755	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LDO37_RS27765	COG1349	DNA-binding transcription factor activity
LDO37_RS27770	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LDO37_RS27835	COG2207	Transcriptional regulator
LDO37_RS27835	COG1917	Cupin 2, conserved barrel domain protein
LDO37_RS27845	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LDO37_RS27850	COG0363	glucosamine-6-phosphate deaminase activity
LDO37_RS27855	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LDO37_RS27870	COG1278	Cold shock
LDO37_RS27880	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LDO37_RS27885	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LDO37_RS27885	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LDO37_RS27900	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
LDO37_RS27950	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LDO37_RS27955	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LDO37_RS27970	COG4336	lyase activity
LDO37_RS27975	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LDO37_RS27995	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
LDO37_RS28000	COG1984	allophanate hydrolase subunit 2
LDO37_RS28030	COG0840	transmembrane signaling receptor activity
LDO37_RS28035	COG0786	glutamate:sodium symporter activity
LDO37_RS28040	COG2515	1-aminocyclopropane-1-carboxylate deaminase
LDO37_RS28045	COG0583	DNA-binding transcription factor activity
LDO37_RS28050	COG0583	DNA-binding transcription factor activity
LDO37_RS28055	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LDO37_RS28065	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
LDO37_RS28070	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LDO37_RS28130	COG0456	acetyltransferase
LDO37_RS28150	COG2135	peptidase activity
LDO37_RS28155	COG3070	regulator of competence-specific genes
LDO37_RS28165	COG2175	clavaminate synthase activity
LDO37_RS28175	COG1228	amidohydrolase
LDO37_RS28180	COG0840	transmembrane signaling receptor activity
LDO37_RS28190	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LDO37_RS28190	COG2146	nitrite reductase [NAD(P)H] activity
LDO37_RS28195	COG1116	anion transmembrane transporter activity
LDO37_RS28200	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LDO37_RS28215	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LDO37_RS28225	COG0243	molybdopterin cofactor binding
LDO37_RS28240	COG1280	lysine exporter protein (LysE YggA)
LDO37_RS28255	COG0463	Glycosyl transferase, family 2
LDO37_RS28255	COG1216	Glycosyl transferase, family 2
LDO37_RS28280	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LDO37_RS28285	COG3852	Histidine kinase
LDO37_RS28290	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
LDO37_RS28300	COG1609	Transcriptional regulator
LDO37_RS28305	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LDO37_RS28310	COG1879	ABC-type sugar transport system periplasmic component
LDO37_RS28315	COG1172	Belongs to the binding-protein-dependent transport system permease family
LDO37_RS28320	COG1129	ABC transporter
LDO37_RS28325	COG1869	D-ribose catabolic process
LDO37_RS28330	COG0583	DNA-binding transcription factor activity
LDO37_RS28335	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
LDO37_RS28345	COG1280	lysine exporter protein (LysE YggA)
LDO37_RS28365	COG2084	Dehydrogenase
LDO37_RS28405	COG0753	catalase activity
LDO37_RS28420	COG0583	DNA-binding transcription factor activity
LDO37_RS28425	COG0668	transmembrane transport
LDO37_RS28430	COG1418	mRNA catabolic process
LDO37_RS28475	COG2755	lipolytic protein G-D-S-L family
LDO37_RS28505	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
LDO37_RS28525	COG0583	DNA-binding transcription factor activity
LDO37_RS28535	COG0625	glutathione transferase activity
LDO37_RS28550	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LDO37_RS28555	COG0067	glutamate synthase
LDO37_RS28555	COG0070	glutamate synthase
LDO37_RS28555	COG0069	glutamate synthase activity
LDO37_RS28570	COG3706	GGDEF domain
LDO37_RS28580	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LDO37_RS28590	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
LDO37_RS28590	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
LDO37_RS28590	COG0506	proline dehydrogenase activity
LDO37_RS28605	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LDO37_RS28610	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LDO37_RS28615	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LDO37_RS28620	COG1121	(ABC) transporter
LDO37_RS28640	COG0259	pyridoxamine-phosphate oxidase activity
LDO37_RS28660	COG2274	protein secretion by the type I secretion system
LDO37_RS28665	COG1063	alcohol dehydrogenase
LDO37_RS28675	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
LDO37_RS28720	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
LDO37_RS28725	COG0840	transmembrane signaling receptor activity
LDO37_RS28735	COG0835	chemotaxis
LDO37_RS28750	COG0745	RESPONSE REGULATOR receiver
LDO37_RS28760	COG1444	tRNA N-acetyltransferase activity
LDO37_RS28775	COG1192	Involved in chromosome partitioning
LDO37_RS29035	COG0840	transmembrane signaling receptor activity
LDO37_RS29110	COG0640	Transcriptional regulator
LDO37_RS29125	COG0786	glutamate:sodium symporter activity
LDO37_RS29290	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
LDO37_RS29295	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LDO37_RS29300	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LDO37_RS29305	COG0697	spore germination
LDO37_RS29310	COG2176	DNA-directed DNA polymerase activity
LDO37_RS29315	COG0517	IMP dehydrogenase activity
LDO37_RS29320	COG2186	Transcriptional regulator
LDO37_RS29325	COG2186	Transcriptional regulator
LDO37_RS29365	COG0840	transmembrane signaling receptor activity
LDO37_RS29385	COG3181	Tripartite tricarboxylate transporter family receptor
LDO37_RS29405	COG1917	Cupin 2, conserved barrel domain protein
LDO37_RS29410	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LDO37_RS29415	COG0800	Aldolase
LDO37_RS29420	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LDO37_RS29425	COG2731	YhcH YjgK YiaL family protein
LDO37_RS29430	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
LDO37_RS29475	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
LDO37_RS29495	COG0330	HflC and HflK could
LDO37_RS29520	COG1196	nuclear chromosome segregation
LDO37_RS29610	COG0210	DNA helicase
LDO37_RS29655	COG0633	Ferredoxin
LDO37_RS29725	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LDO37_RS30160	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
LDO37_RS30175	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
LDO37_RS30210	COG1028	Short-chain dehydrogenase reductase Sdr