locus-tag	class	description
LDO91_RS00010	COG0592	DNA-directed DNA polymerase activity
LDO91_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LDO91_RS00020	COG0187	DNA topoisomerase II activity
LDO91_RS00025	COG0071	Belongs to the small heat shock protein (HSP20) family
LDO91_RS00030	COG3977	Valine--pyruvate aminotransferase
LDO91_RS00045	COG0751	glycine-tRNA ligase activity
LDO91_RS00055	COG2119	membrane
LDO91_RS00080	COG0604	alcohol dehydrogenase
LDO91_RS00085	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
LDO91_RS00090	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
LDO91_RS00095	COG3454	Phosphonate metabolism
LDO91_RS00100	COG4778	phosphonate C-P lyase system protein PhnL
LDO91_RS00105	COG4107	phosphonate C-P lyase system protein PhnK
LDO91_RS00110	COG3627	carbon phosphorus lyase activity
LDO91_RS00115	COG3626	phosphonate metabolism
LDO91_RS00120	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
LDO91_RS00125	COG3624	Phosphonate C-P lyase system protein PhnG
LDO91_RS00130	COG2188	Transcriptional regulator
LDO91_RS00135	COG3639	organic phosphonate transmembrane transporter activity
LDO91_RS00140	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
LDO91_RS00165	COG1739	Uncharacterized protein family UPF0029
LDO91_RS00170	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LDO91_RS00175	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
LDO91_RS00220	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LDO91_RS00225	COG0583	DNA-binding transcription factor activity
LDO91_RS00230	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
LDO91_RS00235	COG2960	long-chain fatty acid transporting porin activity
LDO91_RS00240	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LDO91_RS00245	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LDO91_RS00250	COG1309	transcriptional regulator
LDO91_RS00290	COG4172	Belongs to the ABC transporter superfamily
LDO91_RS00295	COG4166	transmembrane transport
LDO91_RS00300	COG0601	transmembrane transport
LDO91_RS00305	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LDO91_RS00335	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LDO91_RS00335	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LDO91_RS00360	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LDO91_RS00370	COG2197	response regulator
LDO91_RS00380	COG4989	oxidoreductase activity
LDO91_RS00400	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LDO91_RS00405	COG3300	MHYT domain
LDO91_RS00405	COG5001	Diguanylate cyclase
LDO91_RS00410	COG2204	response regulator
LDO91_RS00415	COG3852	Histidine kinase
LDO91_RS00425	COG0174	glutamine synthetase
LDO91_RS00430	COG1217	gtp-binding protein TYPA
LDO91_RS00520	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LDO91_RS00525	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
LDO91_RS00530	COG0339	signal peptide processing
LDO91_RS00535	COG1522	sequence-specific DNA binding
LDO91_RS00540	COG5002	protein histidine kinase activity
LDO91_RS00540	COG5001	Diguanylate cyclase
LDO91_RS00555	COG0589	response to stress
LDO91_RS00560	COG1528	Iron-storage protein
LDO91_RS00570	COG2081	HI0933 family
LDO91_RS00575	COG0667	Aldo Keto reductase
LDO91_RS00620	COG4964	Belongs to the GSP D family
LDO91_RS00685	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LDO91_RS00695	COG3085	chromosome segregation
LDO91_RS00705	COG1322	Protein conserved in bacteria
LDO91_RS00710	COG2226	methyltransferase
LDO91_RS00715	COG3165	ubiquinone biosynthetic process from chorismate
LDO91_RS00720	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LDO91_RS00725	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LDO91_RS00730	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LDO91_RS00735	COG0805	protein transport
LDO91_RS00740	COG0084	hydrolase, TatD family'
LDO91_RS00755	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LDO91_RS00755	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LDO91_RS00785	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LDO91_RS00795	COG1295	ribonuclease BN
LDO91_RS00805	COG0456	acetyltransferase
LDO91_RS00815	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
LDO91_RS00825	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
LDO91_RS00830	COG3031	protein transport across the cell outer membrane
LDO91_RS00840	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LDO91_RS00845	COG1459	type II secretion system
LDO91_RS00850	COG2165	general secretion pathway protein
LDO91_RS00855	COG2165	general secretion pathway protein
LDO91_RS00860	COG2165	general secretion pathway protein
LDO91_RS00865	COG4795	General secretion pathway protein
LDO91_RS00870	COG3156	type II secretion system protein K
LDO91_RS00875	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
LDO91_RS00880	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
LDO91_RS00890	COG0494	nUDIX hydrolase
LDO91_RS00895	COG1218	3'(2'),5'-bisphosphate nucleotidase
LDO91_RS00925	COG2937	Belongs to the GPAT DAPAT family
LDO91_RS00930	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LDO91_RS00935	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
LDO91_RS00940	COG0534	Mate efflux family protein
LDO91_RS00945	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LDO91_RS00960	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LDO91_RS00965	COG4206	TonB-dependent receptor
LDO91_RS00980	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
LDO91_RS01040	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LDO91_RS01050	COG0812	UDP-N-acetylmuramate dehydrogenase activity
LDO91_RS01060	COG1072	(Pantothenic acid kinase))
LDO91_RS01085	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LDO91_RS01090	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LDO91_RS01095	COG0250	Participates in transcription elongation, termination and antitermination
LDO91_RS01110	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LDO91_RS01125	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LDO91_RS01130	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
LDO91_RS01135	COG2816	NAD+ diphosphatase activity
LDO91_RS01145	COG1573	uracil-dna glycosylase
LDO91_RS01150	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LDO91_RS01155	COG3068	Protein conserved in bacteria
LDO91_RS01160	COG1253	flavin adenine dinucleotide binding
LDO91_RS01175	COG0151	Belongs to the GarS family
LDO91_RS01180	COG0138	bifunctional purine biosynthesis protein purh
LDO91_RS01195	COG0840	transmembrane signaling receptor activity
LDO91_RS01200	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
LDO91_RS01205	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LDO91_RS01210	COG2264	protein methyltransferase activity
LDO91_RS01215	COG0439	Biotin carboxylase
LDO91_RS01220	COG0511	ligase activity, forming carbon-carbon bonds
LDO91_RS01225	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
LDO91_RS01235	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LDO91_RS01250	COG2814	Major facilitator Superfamily
LDO91_RS01255	COG2205	protein histidine kinase activity
LDO91_RS01255	COG2198	Histidine kinase
LDO91_RS01255	COG0784	Response regulator, receiver
LDO91_RS01285	COG3842	ATPase activity
LDO91_RS01295	COG1840	ABC-type Fe3 transport system, periplasmic component
LDO91_RS01300	COG2204	response regulator
LDO91_RS01305	COG4191	Histidine kinase
LDO91_RS01315	COG4232	protein-disulfide reductase activity
LDO91_RS01320	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
LDO91_RS01325	COG1027	Aspartate ammonia-lyase
LDO91_RS01335	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LDO91_RS01345	COG2205	protein histidine kinase activity
LDO91_RS01350	COG0745	RESPONSE REGULATOR receiver
LDO91_RS01370	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LDO91_RS01380	COG0534	Mate efflux family protein
LDO91_RS01390	COG0459	protein refolding
LDO91_RS01400	COG1285	pathogenesis
LDO91_RS01410	COG3778	Protein conserved in bacteria
LDO91_RS01445	COG4518	Phage tail assembly chaperone proteins, E, or 41 or 14
LDO91_RS01455	COG4386	tail sheath protein
LDO91_RS01475	COG4387	Mu-like prophage protein GP36
LDO91_RS01485	COG4397	Mu-like prophage major head subunit gpT
LDO91_RS01520	COG4383	Mu-like prophage protein gp29
LDO91_RS01525	COG4373	Mu-like prophage FluMu protein gp28
LDO91_RS01535	COG0640	Transcriptional regulator
LDO91_RS01630	COG2842	Transposition protein
LDO91_RS01635	COG2801	Transposase and inactivated derivatives
LDO91_RS01640	COG3423	Transcriptional regulator
LDO91_RS01655	COG1509	lysine 2,3-aminomutase activity
LDO91_RS01660	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LDO91_RS01695	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
LDO91_RS01700	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LDO91_RS01705	COG1053	succinate dehydrogenase
LDO91_RS01710	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
LDO91_RS01720	COG0584	glycerophosphoryl diester phosphodiesterase
LDO91_RS01725	COG0471	metal ion transport
LDO91_RS01730	COG0688	phosphatidylethanolamine metabolic process
LDO91_RS01735	COG1162	GTPase activity
LDO91_RS01740	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
LDO91_RS01785	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LDO91_RS01790	COG0802	atpase or kinase
LDO91_RS01795	COG0860	N-Acetylmuramoyl-L-alanine amidase
LDO91_RS01800	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LDO91_RS01805	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LDO91_RS01815	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LDO91_RS01820	COG0330	HflC and HflK could
LDO91_RS01825	COG0330	HflC and HflK could
LDO91_RS01830	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
LDO91_RS01835	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LDO91_RS01840	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
LDO91_RS01845	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LDO91_RS01845	COG1017	nitric oxide dioxygenase activity
LDO91_RS01855	COG3083	sulfuric ester hydrolase activity
LDO91_RS01860	COG0557	exoribonuclease II activity
LDO91_RS01865	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LDO91_RS01875	COG3954	Phosphoribulokinase
LDO91_RS01885	COG0429	hydrolase of the alpha beta-hydrolase fold
LDO91_RS01890	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LDO91_RS01910	COG0488	(ABC) transporter
LDO91_RS01930	COG1047	Peptidyl-prolyl cis-trans
LDO91_RS01935	COG1446	asparaginase
LDO91_RS01940	COG2900	Belongs to the SlyX family
LDO91_RS01950	COG0545	Peptidyl-prolyl cis-trans isomerase
LDO91_RS01955	COG2964	Protein conserved in bacteria
LDO91_RS01960	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
LDO91_RS01965	COG2923	Belongs to the DsrF TusC family
LDO91_RS01985	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LDO91_RS01990	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LDO91_RS02005	COG0051	transcription antitermination factor activity, RNA binding
LDO91_RS02010	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LDO91_RS02015	COG0088	Forms part of the polypeptide exit tunnel
LDO91_RS02025	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LDO91_RS02030	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LDO91_RS02035	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LDO91_RS02045	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LDO91_RS02055	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LDO91_RS02065	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LDO91_RS02070	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LDO91_RS02075	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LDO91_RS02080	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LDO91_RS02100	COG1841	ribosomal large subunit assembly
LDO91_RS02105	COG0200	Binds to the 23S rRNA
LDO91_RS02110	COG0201	protein transport
LDO91_RS02115	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LDO91_RS02120	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LDO91_RS02125	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LDO91_RS02135	COG0202	RNA polymerase activity
LDO91_RS02140	COG0203	ribosomal protein L17
LDO91_RS02145	COG2873	o-acetylhomoserine
LDO91_RS02155	COG0545	Peptidyl-prolyl cis-trans isomerase
LDO91_RS02160	COG3266	domain, Protein
LDO91_RS02160	COG3061	Opacity-associated protein A
LDO91_RS02195	COG0697	spore germination
LDO91_RS02200	COG2153	protein acetylation
LDO91_RS02210	COG0737	Belongs to the 5'-nucleotidase family
LDO91_RS02215	COG1648	precorrin-2 dehydrogenase activity
LDO91_RS02215	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LDO91_RS02220	COG0175	sulfate reduction
LDO91_RS02225	COG2895	sulfate adenylyltransferase (ATP) activity
LDO91_RS02230	COG3273	potassium ion transport
LDO91_RS02230	COG0471	metal ion transport
LDO91_RS02235	COG0529	Catalyzes the synthesis of activated sulfate
LDO91_RS02255	COG1136	(ABC) transporter
LDO91_RS02270	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
LDO91_RS02275	COG0540	Belongs to the ATCase OTCase family
LDO91_RS02280	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LDO91_RS02285	COG2235	arginine
LDO91_RS02320	COG4269	membrane
LDO91_RS02325	COG0501	Belongs to the peptidase M48B family
LDO91_RS02330	COG0251	oxidation-reduction process
LDO91_RS02340	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
LDO91_RS02350	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
LDO91_RS02360	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LDO91_RS02365	COG3284	Transcriptional regulator
LDO91_RS02580	COG0729	surface antigen
LDO91_RS02585	COG2911	Protein conserved in bacteria
LDO91_RS02590	COG2105	PFAM AIG2 family protein
LDO91_RS02595	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
LDO91_RS02600	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
LDO91_RS02605	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LDO91_RS02610	COG0163	prenyltransferase activity
LDO91_RS02620	COG1178	ABC-type Fe3 transport system permease component
LDO91_RS02625	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
LDO91_RS02635	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LDO91_RS02640	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LDO91_RS02645	COG1447	Phosphotransferase system cellobiose-specific component IIA
LDO91_RS02650	COG1486	melibiose metabolic process
LDO91_RS02660	COG1609	Transcriptional regulator
LDO91_RS02670	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
LDO91_RS02710	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
LDO91_RS02720	COG0646	methionine synthase
LDO91_RS02720	COG1410	methionine synthase
LDO91_RS02725	COG0527	aspartate kinase activity
LDO91_RS02730	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
LDO91_RS02740	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LDO91_RS02755	COG0629	single-stranded DNA binding
LDO91_RS02760	COG2200	EAL domain
LDO91_RS02760	COG2199	diguanylate cyclase activity
LDO91_RS02785	COG3409	Peptidoglycan-binding domain 1 protein
LDO91_RS02785	COG3267	Type II secretory pathway component ExeA
LDO91_RS02795	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LDO91_RS02800	COG1459	type II secretion system
LDO91_RS02810	COG2165	general secretion pathway protein
LDO91_RS02815	COG2165	general secretion pathway protein
LDO91_RS02845	COG1077	Cell shape determining protein MreB Mrl
LDO91_RS02850	COG1792	Involved in formation and maintenance of cell shape
LDO91_RS02855	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
LDO91_RS02860	COG0424	maF-like protein
LDO91_RS02870	COG3164	Protein of unknown function
LDO91_RS02875	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LDO91_RS02880	COG0312	modulator of DNA gyrase
LDO91_RS02885	COG3028	Belongs to the UPF0307 family
LDO91_RS02890	COG0312	modulator of DNA gyrase
LDO91_RS02935	COG0758	DNA mediated transformation
LDO91_RS02950	COG0582	viral genome integration into host DNA
LDO91_RS02995	COG0795	lipopolysaccharide-transporting ATPase activity
LDO91_RS03000	COG0795	lipopolysaccharide-transporting ATPase activity
LDO91_RS03010	COG2927	DNA polymerase III (CHI subunit)
LDO91_RS03015	COG0525	valine-tRNA ligase activity
LDO91_RS03020	COG0204	Acyl-transferase
LDO91_RS03030	COG5007	Belongs to the BolA IbaG family
LDO91_RS03040	COG2854	intermembrane phospholipid transfer
LDO91_RS03045	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LDO91_RS03050	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LDO91_RS03055	COG1127	ABC transporter
LDO91_RS03065	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
LDO91_RS03065	COG0517	IMP dehydrogenase activity
LDO91_RS03070	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
LDO91_RS03085	COG1137	ATPase activity
LDO91_RS03095	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LDO91_RS03100	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LDO91_RS03105	COG1660	Displays ATPase and GTPase activities
LDO91_RS03110	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LDO91_RS03115	COG2239	Acts as a magnesium transporter
LDO91_RS03135	COG5002	protein histidine kinase activity
LDO91_RS03140	COG0745	RESPONSE REGULATOR receiver
LDO91_RS03150	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
LDO91_RS03155	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LDO91_RS03160	COG0564	pseudouridine synthase activity
LDO91_RS03165	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LDO91_RS03180	COG2358	TRAP transporter, solute receptor (TAXI family
LDO91_RS03185	COG1438	arginine binding
LDO91_RS03195	COG0142	geranyltranstransferase activity
LDO91_RS03200	COG0261	This protein binds to 23S rRNA in the presence of protein L20
LDO91_RS03210	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LDO91_RS03215	COG3610	response to peptide
LDO91_RS03220	COG3610	response to peptide
LDO91_RS03235	COG2967	ApaG domain
LDO91_RS03245	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
LDO91_RS03255	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
LDO91_RS03275	COG0066	3-isopropylmalate dehydratase activity
LDO91_RS03280	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LDO91_RS03285	COG0473	3-isopropylmalate dehydrogenase activity
LDO91_RS03290	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LDO91_RS03295	COG1309	transcriptional regulator
LDO91_RS03315	COG0671	phosphoesterase, PA-phosphatase related
LDO91_RS03325	COG0583	DNA-binding transcription factor activity
LDO91_RS03330	COG1022	Amp-dependent synthetase and ligase
LDO91_RS03340	COG2963	transposase activity
LDO91_RS03345	COG0028	Belongs to the TPP enzyme family
LDO91_RS03355	COG5002	protein histidine kinase activity
LDO91_RS03355	COG5001	Diguanylate cyclase
LDO91_RS03355	COG3447	MASE1 domain protein
LDO91_RS03365	COG0469	pyruvate kinase activity
LDO91_RS03370	COG1349	DNA-binding transcription factor activity
LDO91_RS03375	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LDO91_RS03385	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
LDO91_RS03410	COG0840	transmembrane signaling receptor activity
LDO91_RS03435	COG0358	DNA primase activity
LDO91_RS03440	COG1610	YqeY-like protein
LDO91_RS03445	COG0828	Belongs to the bacterial ribosomal protein bS21 family
LDO91_RS03450	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LDO91_RS03455	COG0596	Alpha beta hydrolase
LDO91_RS03460	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
LDO91_RS03465	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LDO91_RS03470	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LDO91_RS03480	COG0288	reversible hydration of carbon dioxide
LDO91_RS03485	COG0659	secondary active sulfate transmembrane transporter activity
LDO91_RS03490	COG1131	(ABC) transporter
LDO91_RS03495	COG0842	Transport permease protein
LDO91_RS03505	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
LDO91_RS03510	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LDO91_RS03520	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LDO91_RS03525	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LDO91_RS03535	COG1643	Atp-dependent helicase
LDO91_RS03540	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LDO91_RS03545	COG1752	Esterase of the alpha-beta hydrolase superfamily
LDO91_RS03550	COG1049	propionate catabolic process, 2-methylcitrate cycle
LDO91_RS03565	COG0004	ammonium transporteR
LDO91_RS03570	COG1840	ABC-type Fe3 transport system, periplasmic component
LDO91_RS03580	COG3842	ATPase activity
LDO91_RS03585	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LDO91_RS03600	COG2971	BadF BadG BcrA BcrD
LDO91_RS03610	COG4608	Belongs to the ABC transporter superfamily
LDO91_RS03615	COG0444	Belongs to the ABC transporter superfamily
LDO91_RS03620	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LDO91_RS03630	COG0747	negative chemotaxis
LDO91_RS03635	COG2205	protein histidine kinase activity
LDO91_RS03635	COG0784	Response regulator, receiver
LDO91_RS03640	COG2813	Specifically methylates the guanine in position
LDO91_RS03645	COG0628	permease
LDO91_RS03670	COG0739	heme binding
LDO91_RS03675	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LDO91_RS03690	COG2027	D-alanyl-D-alanine carboxypeptidase
LDO91_RS03695	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
LDO91_RS03700	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LDO91_RS03705	COG1534	Rna-binding protein
LDO91_RS03710	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
LDO91_RS03715	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LDO91_RS03720	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LDO91_RS03730	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LDO91_RS03745	COG0779	Required for maturation of 30S ribosomal subunits
LDO91_RS03750	COG0195	Participates in both transcription termination and antitermination
LDO91_RS03755	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LDO91_RS03760	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LDO91_RS03765	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LDO91_RS03770	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LDO91_RS03775	COG1185	polyribonucleotide nucleotidyltransferase activity
LDO91_RS03785	COG0826	peptidase U32
LDO91_RS03790	COG0826	peptidase U32
LDO91_RS03800	COG3154	lipid carrier protein
LDO91_RS03805	COG3153	acetyltransferase
LDO91_RS03860	COG1737	Transcriptional regulator
LDO91_RS03865	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LDO91_RS03870	COG0022	dehydrogenase e1 component
LDO91_RS03875	COG0508	dehydrogenase complex catalyzes the overall conversion of
LDO91_RS03885	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LDO91_RS03895	COG1129	ABC transporter
LDO91_RS03910	COG1172	Belongs to the binding-protein-dependent transport system permease family
LDO91_RS03915	COG1028	Short-chain dehydrogenase reductase Sdr
LDO91_RS03925	COG1063	alcohol dehydrogenase
LDO91_RS03935	COG0084	hydrolase, TatD family'
LDO91_RS03940	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LDO91_RS03950	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
LDO91_RS03955	COG0813	purine-nucleoside phosphorylase activity
LDO91_RS03965	COG0560	Phosphoserine phosphatase
LDO91_RS03975	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LDO91_RS04005	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LDO91_RS04020	COG0583	DNA-binding transcription factor activity
LDO91_RS04030	COG0583	DNA-binding transcription factor activity
LDO91_RS04040	COG1022	Amp-dependent synthetase and ligase
LDO91_RS04055	COG0784	Response regulator, receiver
LDO91_RS04055	COG3437	response regulator, receiver
LDO91_RS04060	COG2059	Chromate
LDO91_RS04105	COG1929	Belongs to the glycerate kinase type-1 family
LDO91_RS04110	COG2610	gluconate transmembrane transporter activity
LDO91_RS04115	COG3835	regulator
LDO91_RS04145	COG2258	MOSC domain
LDO91_RS04165	COG2171	N-acyltransferase activity
LDO91_RS04170	COG3141	response to X-ray
LDO91_RS04175	COG0583	DNA-binding transcription factor activity
LDO91_RS04190	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
LDO91_RS04195	COG1074	ATP-dependent DNA helicase activity
LDO91_RS04200	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LDO91_RS04220	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
LDO91_RS04225	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
LDO91_RS04230	COG2166	iron-sulfur cluster assembly
LDO91_RS04240	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LDO91_RS04245	COG0693	protein deglycase activity
LDO91_RS04250	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LDO91_RS04265	COG1595	DNA-templated transcription, initiation
LDO91_RS04275	COG2211	Major facilitator Superfamily
LDO91_RS04280	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LDO91_RS04290	COG2813	Specifically methylates the guanine in position
LDO91_RS04295	COG0271	Belongs to the BolA IbaG family
LDO91_RS04300	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
LDO91_RS04310	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
LDO91_RS04315	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
LDO91_RS04320	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
LDO91_RS04325	COG2871	sodium ion transport
LDO91_RS04330	COG1477	protein flavinylation
LDO91_RS04350	COG1360	Flagellar Motor Protein
LDO91_RS04375	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LDO91_RS04395	COG3325	Belongs to the glycosyl hydrolase 18 family
LDO91_RS04395	COG3469	chitinase activity
LDO91_RS04400	COG0733	neurotransmitter:sodium symporter activity
LDO91_RS04425	COG1720	tRNA m6t6A37 methyltransferase activity
LDO91_RS04430	COG0254	rRNA binding
LDO91_RS04440	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
LDO91_RS04450	COG2217	Heavy metal translocating P-type atpase
LDO91_RS04450	COG2608	mercury ion transmembrane transporter activity
LDO91_RS04470	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
LDO91_RS04520	COG0784	Response regulator, receiver
LDO91_RS04520	COG0835	chemotaxis
LDO91_RS04525	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
LDO91_RS04530	COG1815	bacterial-type flagellum-dependent cell motility
LDO91_RS04535	COG1558	bacterial-type flagellum-dependent cell motility
LDO91_RS04545	COG1749	Flagellar hook protein flgE
LDO91_RS04550	COG4786	Flagellar basal body rod
LDO91_RS04565	COG1706	bacterial-type flagellum-dependent cell motility
LDO91_RS04570	COG1705	Flagellar rod assembly protein muramidase FlgJ
LDO91_RS04570	COG3951	Flagellar rod assembly protein muramidase FlgJ
LDO91_RS04580	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LDO91_RS04590	COG2190	(PTS) system
LDO91_RS04600	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LDO91_RS04610	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
LDO91_RS04630	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
LDO91_RS04635	COG0789	Transcriptional regulator
LDO91_RS04645	COG0330	HflC and HflK could
LDO91_RS04650	COG3118	belongs to the thioredoxin family
LDO91_RS04655	COG0300	oxidoreductase activity
LDO91_RS04660	COG1090	epimerase
LDO91_RS04685	COG0622	Phosphoesterase
LDO91_RS04705	COG3710	Transcriptional regulator
LDO91_RS04710	COG0326	Molecular chaperone. Has ATPase activity
LDO91_RS04720	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
LDO91_RS04725	COG0250	Participates in transcription elongation, termination and antitermination
LDO91_RS04730	COG0367	asparagine synthase
LDO91_RS04735	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LDO91_RS04735	COG4651	solute:proton antiporter activity
LDO91_RS04740	COG1940	carbohydrate kinase activity
LDO91_RS04740	COG1846	Transcriptional regulator
LDO91_RS04745	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LDO91_RS04750	COG0363	glucosamine-6-phosphate deaminase activity
LDO91_RS04755	COG1263	PTS System
LDO91_RS04755	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LDO91_RS04755	COG2190	(PTS) system
LDO91_RS04760	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LDO91_RS04770	COG2963	transposase activity
LDO91_RS04775	COG0735	belongs to the Fur family
LDO91_RS04785	COG0716	FMN binding
LDO91_RS04795	COG0596	Alpha beta hydrolase
LDO91_RS04800	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
LDO91_RS04805	COG0033	Phosphoglucomutase
LDO91_RS04815	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LDO91_RS04830	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
LDO91_RS04835	COG1053	succinate dehydrogenase
LDO91_RS04845	COG0567	Dehydrogenase, E1 component
LDO91_RS04850	COG0508	dehydrogenase complex catalyzes the overall conversion of
LDO91_RS04855	COG0045	succinate-CoA ligase (ADP-forming) activity
LDO91_RS04865	COG0859	PFAM glycosyl transferase family 9
LDO91_RS04870	COG1132	(ABC) transporter
LDO91_RS04875	COG0076	glutamate decarboxylase activity
LDO91_RS04895	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LDO91_RS04900	COG1121	(ABC) transporter
LDO91_RS04905	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
LDO91_RS04910	COG0739	heme binding
LDO91_RS04940	COG1560	Kdo2-lipid A biosynthetic process
LDO91_RS04950	COG3102	Protein conserved in bacteria
LDO91_RS04955	COG0788	formyltetrahydrofolate deformylase activity
LDO91_RS04965	COG1199	ATP-dependent helicase activity
LDO91_RS04970	COG1214	PFAM Peptidase M22, glycoprotease
LDO91_RS04985	COG0596	Alpha beta hydrolase
LDO91_RS04990	COG0318	PFAM AMP-dependent synthetase and ligase
LDO91_RS04995	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
LDO91_RS05010	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
LDO91_RS05015	COG2894	cell division
LDO91_RS05025	COG3100	YcgL domain-containing protein
LDO91_RS05030	COG2951	lytic endotransglycosylase activity
LDO91_RS05035	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LDO91_RS05055	COG0840	transmembrane signaling receptor activity
LDO91_RS05080	COG1175	transmembrane transport
LDO91_RS05085	COG0395	ABC-type sugar transport system, permease component
LDO91_RS05090	COG3842	ATPase activity
LDO91_RS05110	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LDO91_RS05115	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
LDO91_RS05120	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
LDO91_RS05130	COG0431	NADPH-dependent FMN reductase
LDO91_RS05145	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
LDO91_RS05155	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LDO91_RS05160	COG2204	response regulator
LDO91_RS05170	COG0544	peptidyl-prolyl cis-trans isomerase activity
LDO91_RS05185	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
LDO91_RS05190	COG0776	regulation of translation
LDO91_RS05195	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LDO91_RS05200	COG1555	photosystem II stabilization
LDO91_RS05215	COG0232	Belongs to the dGTPase family. Type 2 subfamily
LDO91_RS05220	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
LDO91_RS05225	COG0436	Aminotransferase
LDO91_RS05230	COG1169	isochorismate synthase
LDO91_RS05235	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
LDO91_RS05275	COG0477	Major facilitator Superfamily
LDO91_RS05290	COG0857	belongs to the CobB CobQ family
LDO91_RS05290	COG0280	phosphate acetyltransferase
LDO91_RS05295	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LDO91_RS05300	COG3092	negative regulation of chromosome organization
LDO91_RS05310	COG4120	Belongs to the binding-protein-dependent transport system permease family
LDO91_RS05315	COG1122	ATPase activity
LDO91_RS05320	COG2199	diguanylate cyclase activity
LDO91_RS05320	COG2203	Gaf domain
LDO91_RS05325	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LDO91_RS05330	COG0653	protein targeting
LDO91_RS05340	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LDO91_RS05345	COG2186	Transcriptional regulator
LDO91_RS05355	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LDO91_RS05355	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LDO91_RS05360	COG0489	protein tyrosine kinase activity
LDO91_RS05365	COG5492	domain, Protein
LDO91_RS05370	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
LDO91_RS05375	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LDO91_RS05380	COG3715	PTS system
LDO91_RS05385	COG3716	PTS system mannose fructose sorbose family IID component
LDO91_RS05390	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
LDO91_RS05390	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LDO91_RS05395	COG0730	response to heat
LDO91_RS05405	COG0572	uridine kinase
LDO91_RS05410	COG2982	Protein involved in outer membrane biogenesis
LDO91_RS05420	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
LDO91_RS05425	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LDO91_RS05430	COG3738	Protein conserved in bacteria
LDO91_RS05435	COG0659	secondary active sulfate transmembrane transporter activity
LDO91_RS05440	COG1530	ribonuclease E activity
LDO91_RS05445	COG0564	pseudouridine synthase activity
LDO91_RS05450	COG0424	maF-like protein
LDO91_RS05455	COG1399	metal-binding, possibly nucleic acid-binding protein
LDO91_RS05465	COG0416	fatty acid biosynthetic process
LDO91_RS05470	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LDO91_RS05475	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LDO91_RS05495	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LDO91_RS05500	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LDO91_RS05505	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LDO91_RS05515	COG0084	hydrolase, TatD family'
LDO91_RS05520	COG1263	PTS System
LDO91_RS05520	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LDO91_RS05525	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
LDO91_RS05530	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LDO91_RS05545	COG3721	Heme iron utilization protein
LDO91_RS05550	COG0748	coenzyme F420 binding
LDO91_RS05565	COG0733	neurotransmitter:sodium symporter activity
LDO91_RS05575	COG4667	esterase of the alpha-beta hydrolase superfamily
LDO91_RS05585	COG1940	carbohydrate kinase activity
LDO91_RS05590	COG0784	Response regulator, receiver
LDO91_RS05590	COG0835	chemotaxis
LDO91_RS05595	COG1028	Short-chain dehydrogenase reductase Sdr
LDO91_RS05600	COG0616	signal peptide processing
LDO91_RS05610	COG0539	negative regulation of cytoplasmic translation
LDO91_RS05620	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
LDO91_RS05625	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
LDO91_RS05675	COG0583	DNA-binding transcription factor activity
LDO91_RS05685	COG0686	Belongs to the AlaDH PNT family
LDO91_RS05700	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
LDO91_RS05705	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LDO91_RS05715	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LDO91_RS05725	COG0156	8-amino-7-oxononanoate synthase activity
LDO91_RS05730	COG2226	methyltransferase
LDO91_RS05735	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
LDO91_RS05745	COG0501	Belongs to the peptidase M48B family
LDO91_RS05755	COG1028	Short-chain dehydrogenase reductase Sdr
LDO91_RS05770	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LDO91_RS05795	COG3923	Primosomal replication protein n
LDO91_RS05800	COG0730	response to heat
LDO91_RS05805	COG1199	ATP-dependent helicase activity
LDO91_RS05810	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
LDO91_RS05820	COG0587	DNA-directed DNA polymerase activity
LDO91_RS05840	COG1757	Na H antiporter
LDO91_RS05855	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LDO91_RS05860	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LDO91_RS05865	COG0131	Imidazoleglycerol-phosphate dehydratase
LDO91_RS05865	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
LDO91_RS05870	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LDO91_RS05875	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
LDO91_RS05885	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LDO91_RS05885	COG0140	phosphoribosyl-ATP diphosphatase activity
LDO91_RS05890	COG3012	SEC-C Motif Domain Protein
LDO91_RS05895	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
LDO91_RS05900	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LDO91_RS05905	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LDO91_RS05910	COG0215	cysteine-tRNA ligase activity
LDO91_RS05915	COG1435	thymidine kinase activity
LDO91_RS05930	COG4067	protein conserved in archaea
LDO91_RS05930	COG0189	ligase activity
LDO91_RS05935	COG0500	methyltransferase
LDO91_RS05940	COG4106	trans-aconitate 2-methyltransferase activity
LDO91_RS05945	COG1801	Protein of unknown function DUF72
LDO91_RS05955	COG0217	transcriptional regulatory protein
LDO91_RS05960	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
LDO91_RS05965	COG0632	four-way junction helicase activity
LDO91_RS05970	COG2255	four-way junction helicase activity
LDO91_RS05975	COG1271	oxidase subunit
LDO91_RS05980	COG1294	oxidase, subunit
LDO91_RS05985	COG4890	Cyd operon protein YbgT
LDO91_RS05995	COG0824	Thioesterase
LDO91_RS06000	COG0811	peptide transport
LDO91_RS06015	COG0823	Involved in the tonB-independent uptake of proteins
LDO91_RS06020	COG2885	chlorophyll binding
LDO91_RS06025	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
LDO91_RS06030	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
LDO91_RS06040	COG0784	Response regulator, receiver
LDO91_RS06040	COG2205	protein histidine kinase activity
LDO91_RS06065	COG1074	ATP-dependent DNA helicase activity
LDO91_RS06080	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LDO91_RS06090	COG1032	radical SAM domain protein
LDO91_RS06105	COG5001	Diguanylate cyclase
LDO91_RS06120	COG0583	DNA-binding transcription factor activity
LDO91_RS06125	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LDO91_RS06135	COG3313	Fe-S protein
LDO91_RS06190	COG2873	o-acetylhomoserine
LDO91_RS06195	COG1522	sequence-specific DNA binding
LDO91_RS06200	COG2205	protein histidine kinase activity
LDO91_RS06230	COG1061	Type III restriction enzyme res subunit
LDO91_RS06240	COG2814	Major facilitator Superfamily
LDO91_RS06250	COG0702	epimerase
LDO91_RS06260	COG4181	ATPase activity
LDO91_RS06280	COG0708	Exodeoxyribonuclease III
LDO91_RS06295	COG1120	ATPase activity
LDO91_RS06305	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LDO91_RS06325	COG1028	Short-chain dehydrogenase reductase Sdr
LDO91_RS06345	COG3385	transposase activity
LDO91_RS06355	COG3040	lipid binding
LDO91_RS06385	COG0697	spore germination
LDO91_RS06395	COG3718	enzyme involved in inositol metabolism
LDO91_RS06400	COG0673	inositol 2-dehydrogenase activity
LDO91_RS06425	COG3655	Transcriptional regulator
LDO91_RS06430	COG0673	inositol 2-dehydrogenase activity
LDO91_RS06435	COG0191	fructose-bisphosphate aldolase activity
LDO91_RS06445	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LDO91_RS06450	COG0673	inositol 2-dehydrogenase activity
LDO91_RS06455	COG3962	Belongs to the TPP enzyme family
LDO91_RS06460	COG1082	Xylose isomerase domain protein TIM barrel
LDO91_RS06465	COG1172	Belongs to the binding-protein-dependent transport system permease family
LDO91_RS06480	COG1609	Transcriptional regulator
LDO91_RS06525	COG2850	peptidyl-arginine hydroxylation
LDO91_RS06540	COG0840	transmembrane signaling receptor activity
LDO91_RS06545	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LDO91_RS06570	COG1278	Cold shock
LDO91_RS06575	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
LDO91_RS06580	COG0542	response to heat
LDO91_RS06590	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LDO91_RS06595	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
LDO91_RS06600	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
LDO91_RS06620	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LDO91_RS06630	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LDO91_RS06635	COG0297	glycogen (starch) synthase activity
LDO91_RS06640	COG0596	Alpha beta hydrolase
LDO91_RS06650	COG3070	regulator of competence-specific genes
LDO91_RS06665	COG0745	RESPONSE REGULATOR receiver
LDO91_RS06670	COG1434	Gram-negative-bacterium-type cell wall biogenesis
LDO91_RS06675	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LDO91_RS06680	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
LDO91_RS06685	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
LDO91_RS06690	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
LDO91_RS06730	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LDO91_RS06750	COG0784	Response regulator, receiver
LDO91_RS06750	COG2205	protein histidine kinase activity
LDO91_RS06755	COG1858	cytochrome C peroxidase
LDO91_RS06760	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LDO91_RS06775	COG0291	Belongs to the bacterial ribosomal protein bL35 family
LDO91_RS06780	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LDO91_RS06790	COG2824	Alkylphosphonate utilization operon protein PhnA
LDO91_RS06805	COG2198	Histidine kinase
LDO91_RS06805	COG0643	Histidine kinase
LDO91_RS06805	COG0784	Response regulator, receiver
LDO91_RS06825	COG0019	diaminopimelate decarboxylase activity
LDO91_RS06830	COG1609	Transcriptional regulator
LDO91_RS06840	COG1172	Belongs to the binding-protein-dependent transport system permease family
LDO91_RS06965	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LDO91_RS06970	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LDO91_RS06985	COG1309	transcriptional regulator
LDO91_RS07000	COG0840	transmembrane signaling receptor activity
LDO91_RS07005	COG2203	Gaf domain
LDO91_RS07005	COG5001	Diguanylate cyclase
LDO91_RS07005	COG3706	GGDEF domain
LDO91_RS07005	COG4251	negative regulation of phosphorylation
LDO91_RS07015	COG0784	Response regulator, receiver
LDO91_RS07015	COG2205	protein histidine kinase activity
LDO91_RS07015	COG5002	protein histidine kinase activity
LDO91_RS07025	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LDO91_RS07050	COG2989	Protein conserved in bacteria
LDO91_RS07055	COG3108	Peptidase M15
LDO91_RS07060	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LDO91_RS07075	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
LDO91_RS07095	COG2197	response regulator
LDO91_RS07100	COG1846	Transcriptional regulator
LDO91_RS07105	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LDO91_RS07110	COG2176	DNA-directed DNA polymerase activity
LDO91_RS07115	COG0517	IMP dehydrogenase activity
LDO91_RS07120	COG1448	Aminotransferase
LDO91_RS07125	COG2770	Histidine kinase
LDO91_RS07125	COG3437	response regulator, receiver
LDO91_RS07130	COG0017	Asparaginyl-tRNA synthetase
LDO91_RS07135	COG0840	transmembrane signaling receptor activity
LDO91_RS07150	COG0720	synthase
LDO91_RS07160	COG1760	l-serine dehydratase
LDO91_RS07165	COG0814	amino acid
LDO91_RS07170	COG0494	nUDIX hydrolase
LDO91_RS07180	COG0784	Response regulator, receiver
LDO91_RS07180	COG2198	Histidine kinase
LDO91_RS07180	COG2205	protein histidine kinase activity
LDO91_RS07200	COG3106	COG3106 Predicted ATPase
LDO91_RS07205	COG3768	UPF0283 membrane protein
LDO91_RS07215	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LDO91_RS07240	COG0840	transmembrane signaling receptor activity
LDO91_RS07250	COG1454	alcohol dehydrogenase
LDO91_RS07265	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
LDO91_RS07300	COG0443	Heat shock 70 kDa protein
LDO91_RS07305	COG0443	Heat shock 70 kDa protein
LDO91_RS07315	COG3706	GGDEF domain
LDO91_RS07330	COG2304	oxidoreductase activity
LDO91_RS07360	COG2801	Transposase and inactivated derivatives
LDO91_RS07440	COG1082	Xylose isomerase domain protein TIM barrel
LDO91_RS07440	COG3185	4-Hydroxyphenylpyruvate dioxygenase
LDO91_RS07445	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
LDO91_RS07455	COG1802	Transcriptional regulator
LDO91_RS07460	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LDO91_RS07465	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
LDO91_RS07470	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
LDO91_RS07480	COG2828	Protein conserved in bacteria
LDO91_RS07490	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LDO91_RS07495	COG2159	amidohydrolase
LDO91_RS07515	COG0667	Aldo Keto reductase
LDO91_RS07545	COG4628	conserved protein (DUF2132)
LDO91_RS07565	COG2721	sulfolactate sulfo-lyase activity
LDO91_RS07575	COG2188	Transcriptional regulator
LDO91_RS07580	COG1063	alcohol dehydrogenase
LDO91_RS07585	COG1028	Short-chain dehydrogenase reductase Sdr
LDO91_RS07590	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LDO91_RS07595	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
LDO91_RS07595	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
LDO91_RS07600	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
LDO91_RS07615	COG1609	Transcriptional regulator
LDO91_RS07620	COG0583	DNA-binding transcription factor activity
LDO91_RS07635	COG4964	Belongs to the GSP D family
LDO91_RS07685	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
LDO91_RS07685	COG2885	chlorophyll binding
LDO91_RS07700	COG2186	Transcriptional regulator
LDO91_RS07705	COG3842	ATPase activity
LDO91_RS07715	COG1175	transmembrane transport
LDO91_RS07720	COG0395	ABC-type sugar transport system, permease component
LDO91_RS07725	COG2706	6-phosphogluconolactonase activity
LDO91_RS07735	COG1070	Carbohydrate kinase
LDO91_RS07745	COG3623	hexulose-6-phosphate isomerase
LDO91_RS07750	COG0235	Class ii aldolase
LDO91_RS07760	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LDO91_RS07765	COG1643	Atp-dependent helicase
LDO91_RS07810	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LDO91_RS07810	COG3321	synthase
LDO91_RS07810	COG0318	PFAM AMP-dependent synthetase and ligase
LDO91_RS07810	COG0300	oxidoreductase activity
LDO91_RS07810	COG1028	Short-chain dehydrogenase reductase Sdr
LDO91_RS07825	COG3300	MHYT domain
LDO91_RS07825	COG5001	Diguanylate cyclase
LDO91_RS07830	COG3622	Belongs to the hyi family
LDO91_RS07835	COG1115	amino acid carrier protein
LDO91_RS07840	COG0277	FAD linked oxidase domain protein
LDO91_RS07845	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LDO91_RS07845	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
LDO91_RS07855	COG2801	Transposase and inactivated derivatives
LDO91_RS07860	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LDO91_RS07880	COG4821	SIS domain
LDO91_RS07885	COG4753	response regulator
LDO91_RS07885	COG2207	Transcriptional regulator
LDO91_RS07910	COG1115	amino acid carrier protein
LDO91_RS07915	COG1028	Short-chain dehydrogenase reductase Sdr
LDO91_RS07940	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LDO91_RS07950	COG3290	protein histidine kinase activity
LDO91_RS07955	COG4565	transcriptional regulatory protein
LDO91_RS07995	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
LDO91_RS08000	COG0372	Belongs to the citrate synthase family
LDO91_RS08005	COG2079	MmgE PrpD family protein
LDO91_RS08025	COG0602	queuosine metabolic process
LDO91_RS08035	COG3706	GGDEF domain
LDO91_RS08085	COG1012	belongs to the aldehyde dehydrogenase family
LDO91_RS08100	COG4176	ABC-type proline glycine betaine transport system permease component
LDO91_RS08105	COG4175	Glycine betaine
LDO91_RS08105	COG3448	diguanylate cyclase activity
LDO91_RS08115	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LDO91_RS08120	COG1760	l-serine dehydratase
LDO91_RS08150	COG1063	alcohol dehydrogenase
LDO91_RS08165	COG1902	pentaerythritol trinitrate reductase activity
LDO91_RS08165	COG0446	pyridine nucleotide-disulphide oxidoreductase
LDO91_RS08170	COG2181	nitrate reductase activity
LDO91_RS08170	COG0247	lactate metabolic process
LDO91_RS08175	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
LDO91_RS08195	COG1785	Belongs to the alkaline phosphatase family
LDO91_RS08230	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LDO91_RS08250	COG3525	Glycosyl hydrolase, family 20, catalytic domain
LDO91_RS08250	COG3291	Pkd domain containing protein
LDO91_RS08255	COG0702	epimerase
LDO91_RS08260	COG1280	lysine exporter protein (LysE YggA)
LDO91_RS08265	COG0840	transmembrane signaling receptor activity
LDO91_RS08270	COG5002	protein histidine kinase activity
LDO91_RS08270	COG2205	protein histidine kinase activity
LDO91_RS08270	COG0784	Response regulator, receiver
LDO91_RS08275	COG0745	RESPONSE REGULATOR receiver
LDO91_RS08280	COG2203	Gaf domain
LDO91_RS08280	COG2200	EAL domain
LDO91_RS08280	COG2199	diguanylate cyclase activity
LDO91_RS08285	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LDO91_RS08290	COG1215	transferase activity, transferring glycosyl groups
LDO91_RS08295	COG0438	transferase activity, transferring glycosyl groups
LDO91_RS08305	COG0438	transferase activity, transferring glycosyl groups
LDO91_RS08310	COG0110	maltose O-acetyltransferase activity
LDO91_RS08320	COG0438	transferase activity, transferring glycosyl groups
LDO91_RS08325	COG0438	transferase activity, transferring glycosyl groups
LDO91_RS08330	COG2204	response regulator
LDO91_RS08335	COG2205	protein histidine kinase activity
LDO91_RS08335	COG3437	response regulator, receiver
LDO91_RS08335	COG3850	Histidine kinase
LDO91_RS08335	COG4999	Histidine kinase
LDO91_RS08340	COG0745	RESPONSE REGULATOR receiver
LDO91_RS08345	COG0489	protein tyrosine kinase activity
LDO91_RS08370	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
LDO91_RS08375	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
LDO91_RS08385	COG1028	Short-chain dehydrogenase reductase Sdr
LDO91_RS08390	COG1164	Oligoendopeptidase f
LDO91_RS08400	COG4139	cobalamin transport
LDO91_RS08405	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
LDO91_RS08465	COG0513	Belongs to the DEAD box helicase family
LDO91_RS08480	COG0583	DNA-binding transcription factor activity
LDO91_RS08490	COG1366	Belongs to the anti-sigma-factor antagonist family
LDO91_RS08495	COG1366	Belongs to the anti-sigma-factor antagonist family
LDO91_RS08500	COG2172	sigma factor antagonist activity
LDO91_RS08510	COG2205	protein histidine kinase activity
LDO91_RS08510	COG3437	response regulator, receiver
LDO91_RS08510	COG3850	Histidine kinase
LDO91_RS08510	COG4999	Histidine kinase
LDO91_RS08515	COG3437	response regulator, receiver
LDO91_RS08530	COG1451	nucleotide metabolic process
LDO91_RS08550	COG0840	transmembrane signaling receptor activity
LDO91_RS08630	COG2195	Cleaves the N-terminal amino acid of tripeptides
LDO91_RS08645	COG2199	diguanylate cyclase activity
LDO91_RS08660	COG2200	EAL domain
LDO91_RS08660	COG2199	diguanylate cyclase activity
LDO91_RS08680	COG0724	RNA recognition motif
LDO91_RS08690	COG1793	dna ligase
LDO91_RS08700	COG0534	Mate efflux family protein
LDO91_RS08705	COG0307	riboflavin synthase, alpha
LDO91_RS08715	COG3001	Fructosamine kinase
LDO91_RS08725	COG3706	GGDEF domain
LDO91_RS08735	COG0791	NLP P60 protein
LDO91_RS08750	COG3148	PFAM DTW domain containing protein
LDO91_RS08755	COG1940	carbohydrate kinase activity
LDO91_RS08760	COG2204	response regulator
LDO91_RS08765	COG3852	Histidine kinase
LDO91_RS08775	COG1858	cytochrome C peroxidase
LDO91_RS08780	COG1858	cytochrome C peroxidase
LDO91_RS08785	COG0723	plastoquinol--plastocyanin reductase activity
LDO91_RS08805	COG0303	'Molybdopterin
LDO91_RS08810	COG0746	molybdenum cofactor guanylyltransferase activity
LDO91_RS08815	COG3842	ATPase activity
LDO91_RS08820	COG4662	Binding-protein-dependent transport system inner membrane component
LDO91_RS08830	COG2204	response regulator
LDO91_RS08835	COG3852	Histidine kinase
LDO91_RS08840	COG0488	(ABC) transporter
LDO91_RS08850	COG1175	transmembrane transport
LDO91_RS08855	COG0395	ABC-type sugar transport system, permease component
LDO91_RS08860	COG3842	ATPase activity
LDO91_RS08865	COG0246	Mannitol dehydrogenase
LDO91_RS08875	COG1070	Carbohydrate kinase
LDO91_RS08885	COG0840	transmembrane signaling receptor activity
LDO91_RS08900	COG0456	acetyltransferase
LDO91_RS08920	COG0840	transmembrane signaling receptor activity
LDO91_RS08925	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LDO91_RS08955	COG3383	formate dehydrogenase (NAD+) activity
LDO91_RS08955	COG0243	molybdopterin cofactor binding
LDO91_RS08960	COG0437	4 iron, 4 sulfur cluster binding
LDO91_RS08965	COG2864	formate dehydrogenase
LDO91_RS08970	COG5002	protein histidine kinase activity
LDO91_RS08975	COG0004	ammonium transporteR
LDO91_RS08980	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LDO91_RS08985	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
LDO91_RS08995	COG1177	transmembrane transport
LDO91_RS09005	COG3842	ATPase activity
LDO91_RS09030	COG1486	melibiose metabolic process
LDO91_RS09035	COG0037	tRNA processing
LDO91_RS09040	COG0589	response to stress
LDO91_RS09045	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LDO91_RS09060	COG2217	Heavy metal translocating P-type atpase
LDO91_RS09070	COG2010	Cytochrome c
LDO91_RS09085	COG3278	Belongs to the heme-copper respiratory oxidase family
LDO91_RS09100	COG2205	protein histidine kinase activity
LDO91_RS09100	COG0784	Response regulator, receiver
LDO91_RS09115	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LDO91_RS09125	COG3568	Endonuclease Exonuclease Phosphatase
LDO91_RS09140	COG3120	sequence-specific DNA binding
LDO91_RS09145	COG1067	ATP-dependent peptidase activity
LDO91_RS09150	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LDO91_RS09165	COG0488	(ABC) transporter
LDO91_RS09175	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LDO91_RS09175	COG0116	Belongs to the methyltransferase superfamily
LDO91_RS09185	COG0167	dihydroorotate dehydrogenase activity
LDO91_RS09190	COG2902	Dehydrogenase
LDO91_RS09200	COG0308	aminopeptidase N
LDO91_RS09215	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
LDO91_RS09220	COG1956	GAF domain-containing protein
LDO91_RS09225	COG1132	(ABC) transporter
LDO91_RS09230	COG2995	paraquat-inducible protein a
LDO91_RS09235	COG3008	intermembrane lipid transfer
LDO91_RS09240	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
LDO91_RS09240	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LDO91_RS09260	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LDO91_RS09265	COG1666	GTP binding
LDO91_RS09270	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LDO91_RS09270	COG1648	precorrin-2 dehydrogenase activity
LDO91_RS09275	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LDO91_RS09280	COG4597	amino acid ABC transporter
LDO91_RS09285	COG0765	amino acid transport
LDO91_RS09290	COG1126	abc transporter atp-binding protein
LDO91_RS09295	COG0670	Belongs to the BI1 family
LDO91_RS09300	COG2920	part of a sulfur-relay system
LDO91_RS09305	COG1254	Belongs to the acylphosphatase family
LDO91_RS09410	COG0631	protein serine/threonine phosphatase activity
LDO91_RS09445	COG2815	serine threonine protein kinase
LDO91_RS09445	COG0515	serine threonine protein kinase
LDO91_RS09455	COG3706	GGDEF domain
LDO91_RS09465	COG2010	Cytochrome c
LDO91_RS09475	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LDO91_RS09480	COG1309	transcriptional regulator
LDO91_RS09505	COG2925	Exonuclease
LDO91_RS09510	COG1380	Effector of murein hydrolase LrgA
LDO91_RS09515	COG1346	cytolysis
LDO91_RS09525	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
LDO91_RS09530	COG2963	transposase activity
LDO91_RS09540	COG0500	methyltransferase
LDO91_RS09555	COG0776	regulation of translation
LDO91_RS09565	COG1136	(ABC) transporter
LDO91_RS09585	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LDO91_RS09585	COG0072	phenylalanine-tRNA ligase activity
LDO91_RS09615	COG2133	pyrroloquinoline quinone binding
LDO91_RS09635	COG2350	Protein conserved in bacteria
LDO91_RS09645	COG4134	Bacterial extracellular solute-binding protein
LDO91_RS09650	COG4135	transport system, permease component
LDO91_RS09655	COG4136	ATPase activity
LDO91_RS09660	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LDO91_RS09680	COG0300	oxidoreductase activity
LDO91_RS09685	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LDO91_RS09690	COG2207	Transcriptional regulator
LDO91_RS09695	COG0351	phosphomethylpyrimidine kinase
LDO91_RS09700	COG1116	anion transmembrane transporter activity
LDO91_RS09705	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LDO91_RS09710	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LDO91_RS09715	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LDO91_RS09720	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
LDO91_RS09760	COG4397	Mu-like prophage major head subunit gpT
LDO91_RS09780	COG0116	Belongs to the methyltransferase superfamily
LDO91_RS09780	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LDO91_RS09785	COG0564	pseudouridine synthase activity
LDO91_RS09795	COG0733	neurotransmitter:sodium symporter activity
LDO91_RS09805	COG0626	cystathionine gamma-synthase activity
LDO91_RS09810	COG0519	Catalyzes the synthesis of GMP from XMP
LDO91_RS09840	COG1842	Phage shock protein A
LDO91_RS09845	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
LDO91_RS09855	COG4168	peptide transport system, permease
LDO91_RS09860	COG4171	peptide transport system, permease
LDO91_RS09870	COG4172	Belongs to the ABC transporter superfamily
LDO91_RS09920	COG0519	Catalyzes the synthesis of GMP from XMP
LDO91_RS09925	COG0745	RESPONSE REGULATOR receiver
LDO91_RS09935	COG1263	PTS System
LDO91_RS09935	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LDO91_RS09935	COG2190	(PTS) system
LDO91_RS09940	COG0840	transmembrane signaling receptor activity
LDO91_RS09955	COG1227	inorganic diphosphatase activity
LDO91_RS09960	COG0167	dihydroorotate dehydrogenase activity
LDO91_RS09975	COG0243	molybdopterin cofactor binding
LDO91_RS09980	COG3005	denitrification pathway
LDO91_RS09985	COG4459	periplasmic nitrate reductase
LDO91_RS09990	COG0390	transport system, permease component
LDO91_RS09995	COG2205	protein histidine kinase activity
LDO91_RS09995	COG2202	Pas domain
LDO91_RS10025	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
LDO91_RS10030	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
LDO91_RS10045	COG3901	Regulator of nitric oxide reductase transcription
LDO91_RS10045	COG0348	domain, Protein
LDO91_RS10085	COG0842	Transport permease protein
LDO91_RS10085	COG1129	ABC transporter
LDO91_RS10105	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LDO91_RS10110	COG1434	Gram-negative-bacterium-type cell wall biogenesis
LDO91_RS10140	COG3706	GGDEF domain
LDO91_RS10150	COG0322	excinuclease ABC activity
LDO91_RS10155	COG2197	response regulator
LDO91_RS10160	COG0417	DNA replication proofreading
LDO91_RS10170	COG4067	protein conserved in archaea
LDO91_RS10170	COG0189	ligase activity
LDO91_RS10175	COG0189	ligase activity
LDO91_RS10185	COG1760	l-serine dehydratase
LDO91_RS10190	COG4943	cyclic-guanylate-specific phosphodiesterase activity
LDO91_RS10220	COG0009	L-threonylcarbamoyladenylate synthase
LDO91_RS10225	COG0613	PHP domain protein
LDO91_RS10235	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LDO91_RS10240	COG0512	Glutamine amidotransferase of anthranilate synthase
LDO91_RS10245	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LDO91_RS10250	COG0135	phosphoribosylanthranilate isomerase activity
LDO91_RS10250	COG0134	indole-3-glycerol-phosphate synthase activity
LDO91_RS10255	COG0133	tryptophan synthase activity
LDO91_RS10260	COG0159	tryptophan synthase activity
LDO91_RS10270	COG1301	dicarboxylic acid transport
LDO91_RS10405	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LDO91_RS10525	COG3421	Type III restriction
LDO91_RS10530	COG2189	Belongs to the N(4) N(6)-methyltransferase family
LDO91_RS10615	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LDO91_RS10620	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LDO91_RS10645	COG0508	dehydrogenase complex catalyzes the overall conversion of
LDO91_RS10645	COG0596	Alpha beta hydrolase
LDO91_RS10695	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LDO91_RS10700	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
LDO91_RS10710	COG4948	Mandelate Racemase Muconate Lactonizing
LDO91_RS10715	COG2721	sulfolactate sulfo-lyase activity
LDO91_RS10725	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LDO91_RS10730	COG3842	ATPase activity
LDO91_RS10735	COG0395	ABC-type sugar transport system, permease component
LDO91_RS10740	COG1175	transmembrane transport
LDO91_RS10750	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LDO91_RS10770	COG0673	inositol 2-dehydrogenase activity
LDO91_RS10800	COG0183	Belongs to the thiolase family
LDO91_RS10830	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LDO91_RS10835	COG2181	nitrate reductase activity
LDO91_RS10835	COG0247	lactate metabolic process
LDO91_RS10840	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
LDO91_RS10845	COG2086	electron transfer activity
LDO91_RS10905	COG0488	(ABC) transporter
LDO91_RS10920	COG4948	Mandelate Racemase Muconate Lactonizing
LDO91_RS10925	COG0179	Fumarylacetoacetate (FAA) hydrolase
LDO91_RS10940	COG3618	amidohydrolase
LDO91_RS10955	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LDO91_RS10960	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LDO91_RS10965	COG0363	glucosamine-6-phosphate deaminase activity
LDO91_RS10980	COG0246	Mannitol dehydrogenase
LDO91_RS10995	COG1609	Transcriptional regulator
LDO91_RS11000	COG3842	ATPase activity
LDO91_RS11005	COG0366	Alpha amylase catalytic
LDO91_RS11010	COG0395	ABC-type sugar transport system, permease component
LDO91_RS11015	COG1175	transmembrane transport
LDO91_RS11020	COG1653	transport
LDO91_RS11025	COG2188	Transcriptional regulator
LDO91_RS11035	COG0010	Belongs to the arginase family
LDO91_RS11040	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
LDO91_RS11045	COG2986	histidine ammonia-lyase
LDO91_RS11055	COG3706	GGDEF domain
LDO91_RS11070	COG0247	lactate metabolic process
LDO91_RS11070	COG0277	FAD linked oxidase domain protein
LDO91_RS11095	COG3385	transposase activity
LDO91_RS11105	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
LDO91_RS11110	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LDO91_RS11115	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LDO91_RS11140	COG2267	carboxylic ester hydrolase activity
LDO91_RS11150	COG1028	Short-chain dehydrogenase reductase Sdr
LDO91_RS11160	COG0454	-acetyltransferase
LDO91_RS11165	COG1028	Short-chain dehydrogenase reductase Sdr
LDO91_RS11170	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LDO91_RS11180	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
LDO91_RS11185	COG1643	Atp-dependent helicase
LDO91_RS11190	COG0281	malic enzyme
LDO91_RS11200	COG2949	membrane
LDO91_RS11225	COG0492	ferredoxin-NADP+ reductase activity
LDO91_RS11230	COG4988	ABC transporter
LDO91_RS11235	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
LDO91_RS11240	COG1879	ABC-type sugar transport system periplasmic component
LDO91_RS11270	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LDO91_RS11295	COG4608	Belongs to the ABC transporter superfamily
LDO91_RS11300	COG0444	Belongs to the ABC transporter superfamily
LDO91_RS11305	COG4166	transmembrane transport
LDO91_RS11310	COG4239	(ABC) transporter, permease
LDO91_RS11315	COG4174	ABC transporter (Permease)
LDO91_RS11320	COG3070	regulator of competence-specific genes
LDO91_RS11340	COG0076	glutamate decarboxylase activity
LDO91_RS11345	COG1737	Transcriptional regulator
LDO91_RS11350	COG1454	alcohol dehydrogenase
LDO91_RS11355	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
LDO91_RS11370	COG1960	acyl-CoA dehydrogenase activity
LDO91_RS11375	COG1309	transcriptional regulator
LDO91_RS11420	COG1882	Formate acetyltransferase
LDO91_RS11435	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LDO91_RS11445	COG3013	Belongs to the UPF0304 family
LDO91_RS11455	COG2718	Belongs to the UPF0229 family
LDO91_RS11460	COG2719	SpoVR family
LDO91_RS11480	COG0463	Glycosyl transferase, family 2
LDO91_RS11495	COG2835	tetraacyldisaccharide 4'-kinase activity
LDO91_RS11500	COG1663	tetraacyldisaccharide 4'-kinase activity
LDO91_RS11505	COG1132	(ABC) transporter
LDO91_RS11510	COG0658	competence protein
LDO91_RS11510	COG2333	competence protein COMEC
LDO91_RS11520	COG4591	ABC-type transport system involved in lipoprotein release permease component
LDO91_RS11525	COG1136	(ABC) transporter
LDO91_RS11530	COG4591	ABC-type transport system involved in lipoprotein release permease component
LDO91_RS11540	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LDO91_RS11555	COG1252	NADH dehydrogenase
LDO91_RS11560	COG2165	general secretion pathway protein
LDO91_RS11590	COG0537	adenosine 5'-monophosphoramidase activity
LDO91_RS11595	COG0840	transmembrane signaling receptor activity
LDO91_RS11620	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LDO91_RS11620	COG4191	Histidine kinase
LDO91_RS11625	COG0471	metal ion transport
LDO91_RS11640	COG5001	Diguanylate cyclase
LDO91_RS11640	COG1716	ATPase activity
LDO91_RS11645	COG0784	Response regulator, receiver
LDO91_RS11645	COG0835	chemotaxis
LDO91_RS11655	COG2205	protein histidine kinase activity
LDO91_RS11660	COG0745	RESPONSE REGULATOR receiver
LDO91_RS11670	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LDO91_RS11675	COG1079	Belongs to the binding-protein-dependent transport system permease family
LDO91_RS11680	COG4603	Belongs to the binding-protein-dependent transport system permease family
LDO91_RS11685	COG3845	ABC transporter
LDO91_RS11690	COG1744	ABC transporter substrate-binding protein PnrA-like
LDO91_RS11700	COG2205	protein histidine kinase activity
LDO91_RS11700	COG0784	Response regulator, receiver
LDO91_RS11715	COG3246	L-lysine catabolic process to acetate
LDO91_RS11720	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LDO91_RS11800	COG0657	acetylesterase activity
LDO91_RS11820	COG0604	alcohol dehydrogenase
LDO91_RS11820	COG3321	synthase
LDO91_RS11825	COG0583	DNA-binding transcription factor activity
LDO91_RS11835	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LDO91_RS11840	COG1845	cytochrome c oxidase, subunit III
LDO91_RS11845	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
LDO91_RS11850	COG0109	protoheme IX farnesyltransferase activity
LDO91_RS11905	COG0438	transferase activity, transferring glycosyl groups
LDO91_RS11955	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LDO91_RS11970	COG0242	peptide deformylase activity
LDO91_RS11975	COG2226	methyltransferase
LDO91_RS12005	COG2199	diguanylate cyclase activity
LDO91_RS12020	COG3126	Type III secretion system lipoprotein chaperone (YscW)
LDO91_RS12025	COG1946	Acyl-CoA thioesterase
LDO91_RS12030	COG1522	sequence-specific DNA binding
LDO91_RS12080	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
LDO91_RS12095	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LDO91_RS12105	COG3848	Pyruvate phosphate dikinase
LDO91_RS12105	COG0574	Belongs to the PEP-utilizing enzyme family
LDO91_RS12140	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LDO91_RS12145	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LDO91_RS12180	COG2963	transposase activity
LDO91_RS12185	COG0435	Glutathione S-transferase
LDO91_RS12205	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LDO91_RS12210	COG0601	transmembrane transport
LDO91_RS12225	COG0314	molybdopterin synthase activity
LDO91_RS12230	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
LDO91_RS12240	COG0521	Mo-molybdopterin cofactor biosynthetic process
LDO91_RS12245	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LDO91_RS12250	COG0391	Required for morphogenesis under gluconeogenic growth conditions
LDO91_RS12255	COG2198	Histidine kinase
LDO91_RS12265	COG0556	nucleotide-excision repair
LDO91_RS12315	COG4657	Part of a membrane complex involved in electron transport
LDO91_RS12325	COG4656	Part of a membrane complex involved in electron transport
LDO91_RS12330	COG4658	electron transport chain
LDO91_RS12335	COG4659	FMN binding
LDO91_RS12340	COG4660	Part of a membrane complex involved in electron transport
LDO91_RS12345	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LDO91_RS12350	COG4172	Belongs to the ABC transporter superfamily
LDO91_RS12360	COG0601	transmembrane transport
LDO91_RS12365	COG0747	negative chemotaxis
LDO91_RS12370	COG0346	lactoylglutathione lyase activity
LDO91_RS12380	COG2885	chlorophyll binding
LDO91_RS12385	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LDO91_RS12390	COG2056	Na+-H+ antiporter family
LDO91_RS12395	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
LDO91_RS12425	COG1012	belongs to the aldehyde dehydrogenase family
LDO91_RS12425	COG1454	alcohol dehydrogenase
LDO91_RS12430	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LDO91_RS12440	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LDO91_RS12445	COG0643	Histidine kinase
LDO91_RS12445	COG2198	Histidine kinase
LDO91_RS12455	COG3082	Protein of unknown function (DUF1414)
LDO91_RS12720	COG5377	YqaJ viral recombinase family
LDO91_RS12740	COG0596	Alpha beta hydrolase
LDO91_RS12740	COG0508	dehydrogenase complex catalyzes the overall conversion of
LDO91_RS12745	COG0022	dehydrogenase e1 component
LDO91_RS12750	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LDO91_RS12755	COG3199	ATP-NAD kinase
LDO91_RS12760	COG3284	Transcriptional regulator
LDO91_RS12770	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LDO91_RS12800	COG2258	MOSC domain
LDO91_RS12810	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LDO91_RS12840	COG0123	including yeast histone deacetylase and acetoin utilization protein
LDO91_RS12855	COG1473	amidohydrolase
LDO91_RS12870	COG1012	belongs to the aldehyde dehydrogenase family
LDO91_RS12880	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LDO91_RS12880	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LDO91_RS12885	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LDO91_RS12890	COG0583	DNA-binding transcription factor activity
LDO91_RS12895	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LDO91_RS12900	COG0778	Nitroreductase
LDO91_RS12905	COG0446	pyridine nucleotide-disulphide oxidoreductase
LDO91_RS12905	COG1902	pentaerythritol trinitrate reductase activity
LDO91_RS12910	COG0616	signal peptide processing
LDO91_RS12915	COG0252	asparaginase activity
LDO91_RS12920	COG3139	Protein of unknown function (DUF1315)
LDO91_RS12935	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LDO91_RS12940	COG0676	glucose-6-phosphate 1-epimerase activity
LDO91_RS12945	COG0745	RESPONSE REGULATOR receiver
LDO91_RS12950	COG2205	protein histidine kinase activity
LDO91_RS12965	COG2226	methyltransferase
LDO91_RS12985	COG1120	ATPase activity
LDO91_RS12990	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LDO91_RS13015	COG1012	belongs to the aldehyde dehydrogenase family
LDO91_RS13030	COG4176	ABC-type proline glycine betaine transport system permease component
LDO91_RS13035	COG4175	Glycine betaine
LDO91_RS13035	COG3448	diguanylate cyclase activity
LDO91_RS13060	COG2983	Belongs to the UPF0260 family
LDO91_RS13085	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LDO91_RS13090	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LDO91_RS13100	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LDO91_RS13105	COG2832	Protein of unknown function (DUF454)
LDO91_RS13110	COG0745	RESPONSE REGULATOR receiver
LDO91_RS13120	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LDO91_RS13125	COG1286	toxin biosynthetic process
LDO91_RS13130	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
LDO91_RS13135	COG0285	dihydrofolate synthase activity
LDO91_RS13145	COG0101	tRNA pseudouridine synthase activity
LDO91_RS13155	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LDO91_RS13160	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LDO91_RS13175	COG0745	RESPONSE REGULATOR receiver
LDO91_RS13180	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LDO91_RS13205	COG3101	peptidyl-lysine hydroxylation
LDO91_RS13210	COG2860	membrane
LDO91_RS13215	COG4221	oxidoreductase activity
LDO91_RS13220	COG0583	DNA-binding transcription factor activity
LDO91_RS13225	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
LDO91_RS13230	COG2890	protein-(glutamine-N5) methyltransferase activity
LDO91_RS13235	COG2840	Smr protein MutS2
LDO91_RS13240	COG2062	phosphohistidine phosphatase, SixA
LDO91_RS13250	COG0366	Alpha amylase catalytic
LDO91_RS13250	COG1470	cell adhesion involved in biofilm formation
LDO91_RS13255	COG0667	Aldo Keto reductase
LDO91_RS13260	COG1172	Belongs to the binding-protein-dependent transport system permease family
LDO91_RS13265	COG1129	ABC transporter
LDO91_RS13285	COG1349	DNA-binding transcription factor activity
LDO91_RS13290	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LDO91_RS13295	COG1070	Carbohydrate kinase
LDO91_RS13310	COG0183	Belongs to the thiolase family
LDO91_RS13315	COG1595	DNA-templated transcription, initiation
LDO91_RS13325	COG2067	long-chain fatty acid transport protein
LDO91_RS13330	COG5265	(ABC) transporter
LDO91_RS13335	COG2853	Lipoprotein
LDO91_RS13340	COG3088	subunit of a heme lyase
LDO91_RS13340	COG4235	cytochrome complex assembly
LDO91_RS13345	COG3088	subunit of a heme lyase
LDO91_RS13345	COG4235	cytochrome complex assembly
LDO91_RS13350	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LDO91_RS13355	COG1138	Cytochrome C-type biogenesis protein
LDO91_RS13360	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
LDO91_RS13365	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LDO91_RS13370	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LDO91_RS13375	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LDO91_RS13380	COG4133	protoheme IX ABC transporter activity
LDO91_RS13390	COG0835	chemotaxis
LDO91_RS13400	COG1192	Involved in chromosome partitioning
LDO91_RS13410	COG2198	Histidine kinase
LDO91_RS13410	COG0643	Histidine kinase
LDO91_RS13410	COG0784	Response regulator, receiver
LDO91_RS13415	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
LDO91_RS13455	COG1987	bacterial-type flagellum assembly
LDO91_RS13505	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LDO91_RS13515	COG1677	Flagellar hook-basal body complex protein FliE
LDO91_RS13535	COG1516	flagellar protein fliS
LDO91_RS13545	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
LDO91_RS13550	COG1334	flagellar protein FlaG
LDO91_RS13555	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LDO91_RS13565	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LDO91_RS13570	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LDO91_RS13575	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LDO91_RS13580	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LDO91_RS13585	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LDO91_RS13605	COG2837	iron assimilation
LDO91_RS13630	COG1393	Belongs to the ArsC family
LDO91_RS13640	COG1876	peptidase activity
LDO91_RS13650	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
LDO91_RS13655	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LDO91_RS13665	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LDO91_RS13680	COG4783	chaperone-mediated protein folding
LDO91_RS13685	COG1393	Belongs to the ArsC family
LDO91_RS13705	COG2233	PERMEase
LDO91_RS13720	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
LDO91_RS13735	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LDO91_RS13740	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
LDO91_RS13745	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LDO91_RS13755	COG3473	Maleate cis-trans isomerase
LDO91_RS13760	COG0179	Fumarylacetoacetate (FAA) hydrolase
LDO91_RS13780	COG0410	ABC transporter
LDO91_RS13785	COG0411	ABC transporter
LDO91_RS13825	COG0121	glutamine amidotransferase
LDO91_RS13830	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
LDO91_RS13835	COG1960	acyl-CoA dehydrogenase activity
LDO91_RS13850	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LDO91_RS13860	COG2226	methyltransferase
LDO91_RS13865	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LDO91_RS13870	COG0741	lytic transglycosylase activity
LDO91_RS13870	COG1388	LysM domain
LDO91_RS13885	COG0347	Belongs to the P(II) protein family
LDO91_RS13905	COG0825	malonyl-CoA metabolic process
LDO91_RS13910	COG0587	DNA-directed DNA polymerase activity
LDO91_RS13915	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LDO91_RS13930	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LDO91_RS13940	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
LDO91_RS13945	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LDO91_RS13950	COG0750	zinc metalloprotease
LDO91_RS13955	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
LDO91_RS13960	COG0575	Belongs to the CDS family
LDO91_RS13965	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LDO91_RS13990	COG0024	Methionine aminopeptidase
LDO91_RS14005	COG0564	pseudouridine synthase activity
LDO91_RS14010	COG3098	single-species biofilm formation
LDO91_RS14040	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
LDO91_RS14050	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
LDO91_RS14050	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
LDO91_RS14065	COG1611	Belongs to the LOG family
LDO91_RS14085	COG2363	Small membrane protein
LDO91_RS14095	COG0583	DNA-binding transcription factor activity
LDO91_RS14100	COG3152	Membrane
LDO91_RS14105	COG0301	tRNA thio-modification
LDO91_RS14105	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LDO91_RS14115	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
LDO91_RS14120	COG1722	exodeoxyribonuclease VII activity
LDO91_RS14125	COG0142	geranyltranstransferase activity
LDO91_RS14130	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LDO91_RS14140	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
LDO91_RS14150	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LDO91_RS14170	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LDO91_RS14170	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LDO91_RS14175	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LDO91_RS14180	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LDO91_RS14195	COG1073	alpha beta
LDO91_RS14200	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
LDO91_RS14205	COG2252	PERMEase
LDO91_RS14210	COG2195	Cleaves the N-terminal amino acid of tripeptides
LDO91_RS14220	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LDO91_RS14220	COG0047	phosphoribosylformylglycinamidine synthase activity
LDO91_RS14225	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
LDO91_RS14235	COG0583	DNA-binding transcription factor activity
LDO91_RS14250	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
LDO91_RS14270	COG4969	Belongs to the N-Me-Phe pilin family
LDO91_RS14280	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LDO91_RS14285	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LDO91_RS14290	COG0497	DNA recombination
LDO91_RS14295	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LDO91_RS14300	COG2914	Belongs to the UPF0125 (RnfH) family
LDO91_RS14305	COG2867	negative regulation of translational initiation
LDO91_RS14320	COG1396	sequence-specific DNA binding
LDO91_RS14370	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
LDO91_RS14415	COG0095	Lipoate-protein ligase
LDO91_RS14425	COG1842	Phage shock protein A
LDO91_RS14450	COG0754	glutathionylspermidine amidase activity
LDO91_RS14490	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LDO91_RS14515	COG0351	phosphomethylpyrimidine kinase
LDO91_RS14535	COG1187	pseudouridine synthase activity
LDO91_RS14540	COG2840	Smr protein MutS2
LDO91_RS14570	COG2877	3-deoxy-8-phosphooctulonate synthase activity
LDO91_RS14575	COG2912	Transglutaminase-like superfamily
LDO91_RS14585	COG2890	protein-(glutamine-N5) methyltransferase activity
LDO91_RS14590	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LDO91_RS14595	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
LDO91_RS14600	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
LDO91_RS14610	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LDO91_RS14615	COG0193	aminoacyl-tRNA hydrolase activity
LDO91_RS14700	COG2706	6-phosphogluconolactonase activity
LDO91_RS14705	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LDO91_RS14725	COG0395	ABC-type sugar transport system, permease component
LDO91_RS14730	COG1024	Enoyl-CoA hydratase
LDO91_RS14735	COG1028	Short-chain dehydrogenase reductase Sdr
LDO91_RS14745	COG3842	ATPase activity
LDO91_RS14755	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LDO91_RS14765	COG1702	phosphate starvation-inducible protein PhoH
LDO91_RS14775	COG4535	Mg2 and Co2 transporter CorC
LDO91_RS14780	COG0815	Transfers the fatty acyl group on membrane lipoproteins
LDO91_RS14790	COG2888	peptidyl-tyrosine sulfation
LDO91_RS14795	COG0495	leucyl-tRNA aminoacylation
LDO91_RS14800	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
LDO91_RS14805	COG1466	dna polymerase III delta subunit
LDO91_RS14810	COG0799	negative regulation of ribosome biogenesis
LDO91_RS14815	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LDO91_RS14820	COG0768	penicillin binding
LDO91_RS14825	COG0772	Belongs to the SEDS family
LDO91_RS14830	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LDO91_RS14835	COG1686	Belongs to the peptidase S11 family
LDO91_RS14845	COG0321	lipoyl(octanoyl) transferase activity
LDO91_RS14850	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LDO91_RS14860	COG0484	heat shock protein binding
LDO91_RS14870	COG1301	dicarboxylic acid transport
LDO91_RS14885	COG0366	Alpha amylase catalytic
LDO91_RS14890	COG1263	PTS System
LDO91_RS14890	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LDO91_RS14895	COG1609	Transcriptional regulator
LDO91_RS14905	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
LDO91_RS14915	COG2011	ABC-type metal ion transport system permease component
LDO91_RS14920	COG1464	Belongs to the NlpA lipoprotein family
LDO91_RS14925	COG1737	Transcriptional regulator
LDO91_RS14930	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LDO91_RS14935	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LDO91_RS14940	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
LDO91_RS14945	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
LDO91_RS14950	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LDO91_RS14960	COG1940	carbohydrate kinase activity
LDO91_RS14965	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LDO91_RS14970	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LDO91_RS14985	COG4948	Mandelate Racemase Muconate Lactonizing
LDO91_RS15000	COG2188	Transcriptional regulator
LDO91_RS15005	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LDO91_RS15015	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
LDO91_RS15015	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
LDO91_RS15020	COG2186	Transcriptional regulator
LDO91_RS15025	COG3437	response regulator, receiver
LDO91_RS15025	COG3850	Histidine kinase
LDO91_RS15025	COG2205	protein histidine kinase activity
LDO91_RS15025	COG4999	Histidine kinase
LDO91_RS15040	COG2200	EAL domain
LDO91_RS15060	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LDO91_RS15065	COG1115	amino acid carrier protein
LDO91_RS15070	COG1584	GPR1 FUN34 yaaH family protein
LDO91_RS15075	COG0519	Catalyzes the synthesis of GMP from XMP
LDO91_RS15075	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LDO91_RS15080	COG0516	GMP reductase activity
LDO91_RS15080	COG0517	IMP dehydrogenase activity
LDO91_RS15095	COG1160	GTP binding
LDO91_RS15100	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LDO91_RS15105	COG2976	Protein conserved in bacteria
LDO91_RS15110	COG0124	histidyl-tRNA synthetase
LDO91_RS15120	COG1426	Protein conserved in bacteria
LDO91_RS15125	COG3063	Type IV pilus biogenesis stability protein PilW
LDO91_RS15135	COG0105	UTP biosynthetic process
LDO91_RS15145	COG2975	iron-sulfur cluster assembly
LDO91_RS15150	COG0633	Ferredoxin
LDO91_RS15170	COG0822	iron-sulfur transferase activity
LDO91_RS15175	COG1104	cysteine desulfurase activity
LDO91_RS15185	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
LDO91_RS15190	COG0483	inositol monophosphate 1-phosphatase activity
LDO91_RS15195	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LDO91_RS15200	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LDO91_RS15205	COG1862	Preprotein translocase
LDO91_RS15210	COG0343	queuine tRNA-ribosyltransferase activity
LDO91_RS15215	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LDO91_RS15225	COG0517	IMP dehydrogenase activity
LDO91_RS15240	COG0583	DNA-binding transcription factor activity
LDO91_RS15245	COG0450	alkyl hydroperoxide reductase
LDO91_RS15250	COG3142	Participates in the control of copper homeostasis
LDO91_RS15265	COG0704	Plays a role in the regulation of phosphate uptake
LDO91_RS15270	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LDO91_RS15275	COG0581	inorganic phosphate transmembrane transporter activity
LDO91_RS15280	COG0573	inorganic phosphate transmembrane transporter activity
LDO91_RS15285	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
LDO91_RS15290	COG0248	Ppx GppA phosphatase
LDO91_RS15300	COG5002	protein histidine kinase activity
LDO91_RS15305	COG0745	RESPONSE REGULATOR receiver
LDO91_RS15320	COG0826	peptidase U32
LDO91_RS15325	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LDO91_RS15345	COG0848	biopolymer transport protein
LDO91_RS15350	COG0811	peptide transport
LDO91_RS15355	COG0811	peptide transport
LDO91_RS15400	COG0542	response to heat
LDO91_RS15410	COG0564	pseudouridine synthase activity
LDO91_RS15415	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LDO91_RS15420	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LDO91_RS15425	COG0077	Prephenate dehydratase
LDO91_RS15425	COG1605	Chorismate mutase
LDO91_RS15430	COG5001	Diguanylate cyclase
LDO91_RS15435	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
LDO91_RS15440	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
LDO91_RS15450	COG0488	(ABC) transporter
LDO91_RS15460	COG0739	heme binding
LDO91_RS15465	COG1605	Chorismate mutase
LDO91_RS15465	COG0287	Prephenate dehydrogenase
LDO91_RS15470	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LDO91_RS15475	COG3275	phosphorelay sensor kinase activity
LDO91_RS15480	COG3279	Response regulator of the LytR AlgR family
LDO91_RS15490	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
LDO91_RS15495	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
LDO91_RS15510	COG1966	Carbon starvation protein
LDO91_RS15520	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
LDO91_RS15525	COG1047	Peptidyl-prolyl cis-trans
LDO91_RS15530	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LDO91_RS15540	COG0196	riboflavin kinase activity
LDO91_RS15545	COG0728	peptidoglycan biosynthetic process
LDO91_RS15550	COG0268	Binds directly to 16S ribosomal RNA
LDO91_RS15555	COG0640	Transcriptional regulator
LDO91_RS15560	COG0583	DNA-binding transcription factor activity
LDO91_RS15565	COG1283	sodium-dependent phosphate transmembrane transporter activity
LDO91_RS15570	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LDO91_RS15575	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LDO91_RS15580	COG0730	response to heat
LDO91_RS15590	COG0494	nUDIX hydrolase
LDO91_RS15605	COG0667	Aldo Keto reductase
LDO91_RS15615	COG2204	response regulator
LDO91_RS15620	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
LDO91_RS15630	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LDO91_RS15635	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LDO91_RS15640	COG4974	Belongs to the 'phage' integrase family
LDO91_RS15645	COG0716	FMN binding
LDO91_RS15660	COG0513	Belongs to the DEAD box helicase family
LDO91_RS15665	COG1737	Transcriptional regulator
LDO91_RS15675	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
LDO91_RS15680	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LDO91_RS15690	COG3842	ATPase activity
LDO91_RS15695	COG0395	ABC-type sugar transport system, permease component
LDO91_RS15700	COG1175	transmembrane transport
LDO91_RS15705	COG2182	Extracellular solute-binding protein
LDO91_RS15710	COG1940	carbohydrate kinase activity
LDO91_RS15720	COG3022	response to hydroperoxide
LDO91_RS15725	COG1115	amino acid carrier protein
LDO91_RS15740	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LDO91_RS15750	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
LDO91_RS15755	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LDO91_RS15760	COG0083	homoserine kinase activity
LDO91_RS15775	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LDO91_RS15785	COG0745	RESPONSE REGULATOR receiver
LDO91_RS15795	COG2198	Histidine kinase
LDO91_RS15795	COG5002	protein histidine kinase activity
LDO91_RS15795	COG0784	Response regulator, receiver
LDO91_RS15800	COG2203	Gaf domain
LDO91_RS15800	COG5001	Diguanylate cyclase
LDO91_RS15800	COG4251	negative regulation of phosphorylation
LDO91_RS15800	COG3706	GGDEF domain
LDO91_RS15805	COG1242	4 iron, 4 sulfur cluster binding
LDO91_RS15810	COG0067	glutamate synthase
LDO91_RS15810	COG0069	glutamate synthase activity
LDO91_RS15810	COG0070	glutamate synthase
LDO91_RS15820	COG0067	glutamate synthase
LDO91_RS15820	COG0069	glutamate synthase activity
LDO91_RS15820	COG0070	glutamate synthase
LDO91_RS15825	COG0493	'glutamate synthase
LDO91_RS15850	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LDO91_RS15855	COG2860	membrane
LDO91_RS15870	COG0655	NAD(P)H dehydrogenase (quinone) activity
LDO91_RS15880	COG0814	amino acid
LDO91_RS15895	COG1119	ATPase activity
LDO91_RS15900	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LDO91_RS15900	COG1522	sequence-specific DNA binding
LDO91_RS15905	COG2313	pseudouridylate synthase activity
LDO91_RS15925	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LDO91_RS15930	COG0505	Belongs to the CarA family
LDO91_RS15950	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
LDO91_RS15955	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LDO91_RS15960	COG0849	cell division
LDO91_RS15965	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
LDO91_RS15975	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LDO91_RS15980	COG0772	Belongs to the SEDS family
LDO91_RS15985	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LDO91_RS15990	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LDO91_RS15995	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LDO91_RS16005	COG0768	penicillin binding
LDO91_RS16010	COG3116	cell division
LDO91_RS16025	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LDO91_RS16030	COG3107	peptidoglycan biosynthetic process
LDO91_RS16035	COG0792	nuclease activity
LDO91_RS16040	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
LDO91_RS16045	COG2823	Periplasmic or secreted lipoprotein
LDO91_RS16050	COG2969	positive regulation of protein catabolic process
LDO91_RS16055	COG0625	glutathione transferase activity
LDO91_RS16060	COG2857	Cytochrome c1
LDO91_RS16065	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
LDO91_RS16070	COG0723	plastoquinol--plastocyanin reductase activity
LDO91_RS16075	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LDO91_RS16085	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
LDO91_RS16090	COG3105	Protein conserved in bacteria
LDO91_RS16095	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LDO91_RS16100	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LDO91_RS16115	COG3150	esterase
LDO91_RS16125	COG3151	Protein conserved in bacteria
LDO91_RS16130	COG0494	nUDIX hydrolase
LDO91_RS16135	COG1538	Outer membrane efflux protein
LDO91_RS16140	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
LDO91_RS16140	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
LDO91_RS16145	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
LDO91_RS16155	COG3025	triphosphatase activity
LDO91_RS16160	COG1392	Phosphate transport regulator
LDO91_RS16165	COG0306	phosphate transporter
LDO91_RS16170	COG4991	sh3 domain protein
LDO91_RS16180	COG3409	Peptidoglycan-binding domain 1 protein
LDO91_RS16180	COG3267	Type II secretory pathway component ExeA
LDO91_RS16185	COG0617	tRNA 3'-terminal CCA addition
LDO91_RS16200	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LDO91_RS16205	COG0508	dehydrogenase complex catalyzes the overall conversion of
LDO91_RS16210	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
LDO91_RS16215	COG2186	Transcriptional regulator
LDO91_RS16225	COG0157	Belongs to the NadC ModD family
LDO91_RS16235	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LDO91_RS16240	COG1459	type II secretion system
LDO91_RS16255	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
LDO91_RS16260	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
LDO91_RS16265	COG0494	nUDIX hydrolase
LDO91_RS16275	COG0336	Belongs to the RNA methyltransferase TrmD family
LDO91_RS16290	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LDO91_RS16295	COG4137	Cytochrome C assembly protein
LDO91_RS16300	COG4536	flavin adenine dinucleotide binding
LDO91_RS16310	COG1854	S-ribosylhomocysteine lyase activity
LDO91_RS16325	COG0612	Peptidase, M16
LDO91_RS16330	COG1238	metal cluster binding
LDO91_RS16340	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
LDO91_RS16345	COG5016	pyruvate
LDO91_RS16345	COG0511	ligase activity, forming carbon-carbon bonds
LDO91_RS16350	COG3630	sodium ion export across plasma membrane
LDO91_RS16395	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
LDO91_RS16400	COG0527	aspartate kinase activity
LDO91_RS16405	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LDO91_RS16410	COG2137	regulation of response to DNA damage stimulus
LDO91_RS16415	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LDO91_RS16420	COG1546	Belongs to the CinA family
LDO91_RS16425	COG3853	Toxic anion resistance protein (TelA)
LDO91_RS16435	COG2255	four-way junction helicase activity
LDO91_RS16460	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LDO91_RS16475	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
LDO91_RS16480	COG0585	pseudouridine synthase activity
LDO91_RS16490	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
LDO91_RS16495	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
LDO91_RS16510	COG3956	TIGRFAM MazG family protein
LDO91_RS16515	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LDO91_RS16520	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LDO91_RS16525	COG4999	Histidine kinase
LDO91_RS16525	COG2205	protein histidine kinase activity
LDO91_RS16525	COG3437	response regulator, receiver
LDO91_RS16525	COG3850	Histidine kinase
LDO91_RS16550	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
LDO91_RS16555	COG1381	Involved in DNA repair and RecF pathway recombination
LDO91_RS16560	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LDO91_RS16565	COG0571	ribonuclease III activity
LDO91_RS16570	COG0681	Belongs to the peptidase S26 family
LDO91_RS16590	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
LDO91_RS16595	COG1595	DNA-templated transcription, initiation
LDO91_RS16600	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
LDO91_RS16630	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LDO91_RS16635	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LDO91_RS16640	COG3079	Belongs to the UPF0149 family
LDO91_RS16645	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
LDO91_RS16655	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LDO91_RS16665	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LDO91_RS16680	COG1279	arginine transmembrane transporter activity
LDO91_RS16690	COG0668	transmembrane transport
LDO91_RS16695	COG0191	fructose-bisphosphate aldolase activity
LDO91_RS16705	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LDO91_RS16715	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LDO91_RS16720	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LDO91_RS16735	COG2356	endonuclease I
LDO91_RS16740	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LDO91_RS16745	COG0189	ligase activity
LDO91_RS16750	COG1678	Uncharacterized ACR, COG1678
LDO91_RS16755	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LDO91_RS16770	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LDO91_RS16775	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LDO91_RS16780	COG0762	integral membrane protein
LDO91_RS16795	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LDO91_RS16800	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LDO91_RS16805	COG2066	Belongs to the glutaminase family
LDO91_RS16815	COG1194	a g-specific adenine glycosylase
LDO91_RS16825	COG0741	lytic transglycosylase activity
LDO91_RS16915	COG0175	sulfate reduction
LDO91_RS16925	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LDO91_RS16950	COG0582	viral genome integration into host DNA
LDO91_RS16975	COG1715	Restriction endonuclease
LDO91_RS16980	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
LDO91_RS16985	COG0732	type I restriction modification DNA specificity domain
LDO91_RS16990	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
LDO91_RS17045	COG0735	belongs to the Fur family
LDO91_RS17060	COG0432	Pfam Uncharacterised protein family UPF0047
LDO91_RS17070	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LDO91_RS17090	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LDO91_RS17095	COG2965	DNA replication, synthesis of RNA primer
LDO91_RS17100	COG0360	Binds together with S18 to 16S ribosomal RNA
LDO91_RS17110	COG1012	belongs to the aldehyde dehydrogenase family
LDO91_RS17120	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LDO91_RS17150	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LDO91_RS17150	COG2070	2-Nitropropane dioxygenase
LDO91_RS17155	COG2207	Transcriptional regulator
LDO91_RS17160	COG4771	TonB-dependent receptor
LDO91_RS17165	COG2375	cellular response to nickel ion
LDO91_RS17165	COG1132	(ABC) transporter
LDO91_RS17170	COG1132	(ABC) transporter
LDO91_RS17185	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LDO91_RS17185	COG2226	methyltransferase
LDO91_RS17185	COG3433	isochorismatase activity
LDO91_RS17190	COG1021	2,3-dihydroxybenzoate-AMP ligase
LDO91_RS17240	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LDO91_RS17250	COG0583	DNA-binding transcription factor activity
LDO91_RS17260	COG0180	Tryptophanyl-tRNA synthetase
LDO91_RS17265	COG0546	phosphoglycolate phosphatase activity
LDO91_RS17270	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LDO91_RS17275	COG0338	D12 class N6 adenine-specific DNA methyltransferase
LDO91_RS17285	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
LDO91_RS17320	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
LDO91_RS17330	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
LDO91_RS17330	COG0678	peroxiredoxin activity
LDO91_RS17335	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LDO91_RS17350	COG0165	Argininosuccinate lyase
LDO91_RS17350	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
LDO91_RS17355	COG0137	argininosuccinate synthase activity
LDO91_RS17360	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LDO91_RS17365	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
LDO91_RS17370	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LDO91_RS17375	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
LDO91_RS17385	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
LDO91_RS17390	COG0460	homoserine dehydrogenase
LDO91_RS17390	COG0527	aspartate kinase activity
LDO91_RS17395	COG0626	cystathionine gamma-synthase activity
LDO91_RS17400	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
LDO91_RS17405	COG0281	malic enzyme
LDO91_RS17415	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LDO91_RS17420	COG1609	Transcriptional regulator
LDO91_RS17430	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
LDO91_RS17440	COG1575	Belongs to the MenA family. Type 1 subfamily
LDO91_RS17450	COG3074	FtsZ-dependent cytokinesis
LDO91_RS17455	COG1494	fructose-1,6-bisphosphatase
LDO91_RS17470	COG3152	Membrane
LDO91_RS17480	COG0149	triose-phosphate isomerase activity
LDO91_RS17485	COG1414	Transcriptional regulator
LDO91_RS17515	COG1045	serine acetyltransferase
LDO91_RS17520	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
LDO91_RS17525	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
LDO91_RS17530	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LDO91_RS17535	COG2373	Large extracellular alpha-helical protein
LDO91_RS17540	COG4953	penicillin-binding protein 1C
LDO91_RS17550	COG4942	peptidase
LDO91_RS17565	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LDO91_RS17595	COG1216	Glycosyl transferase, family 2
LDO91_RS17600	COG1132	(ABC) transporter
LDO91_RS17635	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LDO91_RS17675	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LDO91_RS17680	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
LDO91_RS17760	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LDO91_RS17770	COG0726	polysaccharide deacetylase
LDO91_RS17775	COG0859	PFAM glycosyl transferase family 9
LDO91_RS17780	COG1519	Transferase
LDO91_RS17800	COG1216	Glycosyl transferase, family 2
LDO91_RS17805	COG3642	lipopolysaccharide core region biosynthetic process
LDO91_RS17810	COG0859	PFAM glycosyl transferase family 9
LDO91_RS17815	COG0463	Glycosyl transferase, family 2
LDO91_RS17820	COG0859	PFAM glycosyl transferase family 9
LDO91_RS17825	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LDO91_RS17830	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LDO91_RS17845	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LDO91_RS17850	COG0227	Belongs to the bacterial ribosomal protein bL28 family
LDO91_RS17855	COG2003	Belongs to the UPF0758 family
LDO91_RS17860	COG1858	cytochrome C peroxidase
LDO91_RS17865	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LDO91_RS17870	COG1309	transcriptional regulator
LDO91_RS17875	COG1560	Kdo2-lipid A biosynthetic process
LDO91_RS17880	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LDO91_RS17885	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
LDO91_RS17890	COG1561	YicC-like family, N-terminal region
LDO91_RS17900	COG0194	GDP metabolic process
LDO91_RS17905	COG1758	RNA polymerase activity
LDO91_RS17910	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LDO91_RS17915	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LDO91_RS17935	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LDO91_RS17945	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LDO91_RS17965	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LDO91_RS17970	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LDO91_RS17975	COG2183	response to ionizing radiation
LDO91_RS17980	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
LDO91_RS17985	COG3161	chorismate lyase activity
LDO91_RS17995	COG0705	Rhomboid family
LDO91_RS18010	COG2177	Part of the ABC transporter FtsEX involved in
LDO91_RS18015	COG2884	Cell division ATP-binding protein ftsE
LDO91_RS18020	COG0552	protein localization to endoplasmic reticulum
LDO91_RS18025	COG0742	ribosomal rna small subunit methyltransferase
LDO91_RS18035	COG2095	MarC family integral membrane protein
LDO91_RS18060	COG3274	enterobacterial common antigen metabolic process
LDO91_RS18065	COG4221	oxidoreductase activity
LDO91_RS18070	COG0583	DNA-binding transcription factor activity
LDO91_RS18075	COG0783	Belongs to the Dps family
LDO91_RS18080	COG1609	Transcriptional regulator
LDO91_RS18085	COG1840	ABC-type Fe3 transport system, periplasmic component
LDO91_RS18095	COG3842	ATPase activity
LDO91_RS18100	COG0483	inositol monophosphate 1-phosphatase activity
LDO91_RS18115	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LDO91_RS18120	COG0640	Transcriptional regulator
LDO91_RS18125	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
LDO91_RS18130	COG1280	lysine exporter protein (LysE YggA)
LDO91_RS18140	COG0561	phosphatase activity
LDO91_RS18155	COG3148	PFAM DTW domain containing protein
LDO91_RS18165	COG2199	diguanylate cyclase activity
LDO91_RS18165	COG3287	FIST C domain
LDO91_RS18165	COG2200	EAL domain
LDO91_RS18170	COG1011	Hydrolase
LDO91_RS18175	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
LDO91_RS18185	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LDO91_RS18190	COG0019	diaminopimelate decarboxylase activity
LDO91_RS18205	COG3072	Adenylate cyclase
LDO91_RS18215	COG1587	Uroporphyrinogen-III synthase
LDO91_RS18220	COG2959	enzyme of heme biosynthesis
LDO91_RS18225	COG3071	HemY protein
LDO91_RS18270	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
LDO91_RS18285	COG3118	belongs to the thioredoxin family
LDO91_RS18295	COG0248	Ppx GppA phosphatase
LDO91_RS18305	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LDO91_RS18310	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
LDO91_RS18320	COG2188	Transcriptional regulator
LDO91_RS18325	COG0673	inositol 2-dehydrogenase activity
LDO91_RS18330	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
LDO91_RS18340	COG0514	ATP-dependent DNA helicase (RecQ)
LDO91_RS18345	COG2962	Rard protein
LDO91_RS18355	COG1280	lysine exporter protein (LysE YggA)
LDO91_RS18360	COG0405	Gamma-glutamyltransferase
LDO91_RS18365	COG0210	DNA helicase
LDO91_RS18375	COG3220	belongs to the UPF0276 family
LDO91_RS18405	COG0006	proline dipeptidase activity
LDO91_RS18415	COG2022	thiamine diphosphate biosynthetic process
LDO91_RS18425	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LDO91_RS18435	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
LDO91_RS18440	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LDO91_RS18485	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LDO91_RS18495	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LDO91_RS18500	COG0408	coproporphyrinogen oxidase activity
LDO91_RS18505	COG0009	L-threonylcarbamoyladenylate synthase
LDO91_RS18510	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LDO91_RS18515	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LDO91_RS18520	COG0551	DNA topoisomerase type I activity
LDO91_RS18525	COG2922	Belongs to the Smg family
LDO91_RS18530	COG0758	DNA mediated transformation
LDO91_RS18535	COG1652	LysM domain
LDO91_RS18540	COG0242	peptide deformylase activity
LDO91_RS18550	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LDO91_RS18550	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LDO91_RS18555	COG0569	domain protein
LDO91_RS18560	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LDO91_RS18565	COG1272	protein, Hemolysin III
LDO91_RS18570	COG4326	sporulation control protein
LDO91_RS18575	COG3084	Protein conserved in bacteria
LDO91_RS18585	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LDO91_RS18590	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LDO91_RS18595	COG0204	Acyl-transferase
LDO91_RS18605	COG0606	chelatase, subunit chli
LDO91_RS18615	COG3978	acetolactate synthase activity
LDO91_RS18620	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LDO91_RS18635	COG0583	DNA-binding transcription factor activity
LDO91_RS18640	COG2814	Major facilitator Superfamily
LDO91_RS18645	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LDO91_RS18650	COG0765	amino acid transport
LDO91_RS18660	COG0355	proton-transporting ATP synthase activity, rotational mechanism
LDO91_RS18670	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LDO91_RS18675	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LDO91_RS18680	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LDO91_RS18695	COG0356	it plays a direct role in the translocation of protons across the membrane
LDO91_RS18700	COG3312	ion transport
LDO91_RS18705	COG1475	DNA binding
LDO91_RS18710	COG1192	Involved in chromosome partitioning
LDO91_RS18715	COG0357	Ribosomal RNA small subunit methyltransferase G
LDO91_RS18720	COG0445	tRNA wobble uridine modification
LDO91_RS18725	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LDO91_RS18735	COG0848	biopolymer transport protein
LDO91_RS18745	COG4783	chaperone-mediated protein folding
LDO91_RS18770	COG3712	iron ion homeostasis
LDO91_RS18775	COG1595	DNA-templated transcription, initiation
LDO91_RS18785	COG0706	membrane insertase activity
LDO91_RS18795	COG0594	ribonuclease P activity
LDO91_RS18800	COG0230	Belongs to the bacterial ribosomal protein bL34 family
LDO91_RS18805	COG1126	abc transporter atp-binding protein
LDO91_RS18830	COG4608	Belongs to the ABC transporter superfamily
LDO91_RS18835	COG0444	Belongs to the ABC transporter superfamily
LDO91_RS18865	COG0789	Transcriptional regulator
LDO91_RS18880	COG2264	protein methyltransferase activity
LDO91_RS18895	COG1028	Short-chain dehydrogenase reductase Sdr
LDO91_RS18915	COG1129	ABC transporter
LDO91_RS18920	COG1172	Belongs to the binding-protein-dependent transport system permease family
LDO91_RS18925	COG1172	Belongs to the binding-protein-dependent transport system permease family
LDO91_RS18950	COG0601	transmembrane transport
LDO91_RS18955	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LDO91_RS18960	COG0444	Belongs to the ABC transporter superfamily
LDO91_RS18965	COG4172	Belongs to the ABC transporter superfamily
LDO91_RS18990	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LDO91_RS19000	COG1028	Short-chain dehydrogenase reductase Sdr
LDO91_RS19045	COG2199	diguanylate cyclase activity
LDO91_RS19045	COG2200	EAL domain
LDO91_RS19055	COG0316	Belongs to the HesB IscA family
LDO91_RS19060	COG0719	Fe-S assembly protein
LDO91_RS19065	COG0396	ATPase activity
LDO91_RS19070	COG0719	Fe-S assembly protein
LDO91_RS19080	COG2166	iron-sulfur cluster assembly
LDO91_RS19095	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LDO91_RS19110	COG1070	Carbohydrate kinase
LDO91_RS19120	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LDO91_RS19125	COG0667	Aldo Keto reductase
LDO91_RS19135	COG1172	Belongs to the binding-protein-dependent transport system permease family
LDO91_RS19140	COG1129	ABC transporter
LDO91_RS19150	COG1454	alcohol dehydrogenase
LDO91_RS19160	COG1414	Transcriptional regulator
LDO91_RS19165	COG3437	response regulator, receiver
LDO91_RS19170	COG2205	protein histidine kinase activity
LDO91_RS19170	COG3437	response regulator, receiver
LDO91_RS19170	COG3850	Histidine kinase
LDO91_RS19170	COG4999	Histidine kinase
LDO91_RS19180	COG2311	Membrane
LDO91_RS19250	COG3706	GGDEF domain
LDO91_RS19255	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LDO91_RS19265	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LDO91_RS19270	COG0800	Aldolase
LDO91_RS19285	COG5001	Diguanylate cyclase
LDO91_RS19290	COG1012	belongs to the aldehyde dehydrogenase family
LDO91_RS19295	COG3284	Transcriptional regulator
LDO91_RS19300	COG0583	DNA-binding transcription factor activity
LDO91_RS19305	COG2814	Major facilitator Superfamily
LDO91_RS19310	COG3706	GGDEF domain
LDO91_RS19310	COG4251	negative regulation of phosphorylation
LDO91_RS19310	COG2203	Gaf domain
LDO91_RS19310	COG5001	Diguanylate cyclase
LDO91_RS19405	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LDO91_RS19420	COG1979	alcohol dehydrogenase
LDO91_RS19425	COG0583	DNA-binding transcription factor activity
LDO91_RS19440	COG4172	Belongs to the ABC transporter superfamily
LDO91_RS19475	COG1012	belongs to the aldehyde dehydrogenase family
LDO91_RS19490	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LDO91_RS19495	COG1012	belongs to the aldehyde dehydrogenase family
LDO91_RS19500	COG3384	dioxygenase
LDO91_RS19530	COG3971	2-oxopent-4-enoate hydratase activity
LDO91_RS19540	COG1960	acyl-CoA dehydrogenase activity
LDO91_RS19560	COG1067	ATP-dependent peptidase activity
LDO91_RS19575	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LDO91_RS19590	COG2814	Major facilitator Superfamily
LDO91_RS19640	COG1012	belongs to the aldehyde dehydrogenase family
LDO91_RS19675	COG0840	transmembrane signaling receptor activity
LDO91_RS19680	COG1846	Transcriptional regulator
LDO91_RS19700	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
LDO91_RS19700	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
LDO91_RS19705	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
LDO91_RS19710	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LDO91_RS19740	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LDO91_RS19745	COG2999	glutathione oxidoreductase activity
LDO91_RS19760	COG1278	Cold shock
LDO91_RS19780	COG4452	Inner membrane protein CreD
LDO91_RS19785	COG2205	protein histidine kinase activity
LDO91_RS19790	COG0745	RESPONSE REGULATOR receiver
LDO91_RS19795	COG0730	response to heat
LDO91_RS19800	COG0280	phosphate acetyltransferase
LDO91_RS19805	COG1414	Transcriptional regulator
LDO91_RS19810	COG2188	Transcriptional regulator
LDO91_RS19820	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LDO91_RS19830	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LDO91_RS19830	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LDO91_RS19835	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LDO91_RS19845	COG2205	protein histidine kinase activity
LDO91_RS19850	COG0745	RESPONSE REGULATOR receiver
LDO91_RS19860	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
LDO91_RS19865	COG0534	Mate efflux family protein
LDO91_RS19870	COG0583	DNA-binding transcription factor activity
LDO91_RS19880	COG2962	Rard protein
LDO91_RS19895	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LDO91_RS19905	COG1012	belongs to the aldehyde dehydrogenase family
LDO91_RS19915	COG0583	DNA-binding transcription factor activity
LDO91_RS19925	COG0583	DNA-binding transcription factor activity
LDO91_RS19935	COG0573	inorganic phosphate transmembrane transporter activity
LDO91_RS19940	COG0581	inorganic phosphate transmembrane transporter activity
LDO91_RS19945	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LDO91_RS19955	COG0395	ABC-type sugar transport system, permease component
LDO91_RS19960	COG1175	transmembrane transport
LDO91_RS19970	COG3842	ATPase activity
LDO91_RS19980	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LDO91_RS19990	COG1028	Short-chain dehydrogenase reductase Sdr
LDO91_RS19995	COG1609	Transcriptional regulator
LDO91_RS20035	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LDO91_RS20040	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LDO91_RS20050	COG0789	Transcriptional regulator
LDO91_RS20075	COG2814	Major facilitator Superfamily
LDO91_RS20080	COG0583	DNA-binding transcription factor activity
LDO91_RS20085	COG0523	cobalamin synthesis protein
LDO91_RS20100	COG3485	protocatechuate 3,4-dioxygenase
LDO91_RS20110	COG0725	ABC transporter, periplasmic molybdate-binding protein
LDO91_RS20115	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
LDO91_RS20140	COG1349	DNA-binding transcription factor activity
LDO91_RS20165	COG0612	Peptidase, M16
LDO91_RS20185	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LDO91_RS20220	COG3135	benzoate transporter
LDO91_RS20225	COG1396	sequence-specific DNA binding
LDO91_RS20265	COG2205	protein histidine kinase activity
LDO91_RS20275	COG1404	Belongs to the peptidase S8 family
LDO91_RS20280	COG0583	DNA-binding transcription factor activity
LDO91_RS20345	COG0215	cysteine-tRNA ligase activity
LDO91_RS20350	COG2162	N-hydroxyarylamine O-acetyltransferase activity
LDO91_RS20360	COG1404	Belongs to the peptidase S8 family
LDO91_RS20365	COG0443	Heat shock 70 kDa protein
LDO91_RS20380	COG2207	Transcriptional regulator
LDO91_RS20405	COG2132	Multicopper oxidase
LDO91_RS20410	COG3122	Protein conserved in bacteria
LDO91_RS20435	COG0402	S-adenosylhomocysteine deaminase activity
LDO91_RS20440	COG2197	response regulator
LDO91_RS20455	COG2755	lipolytic protein G-D-S-L family
LDO91_RS20455	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
LDO91_RS20470	COG0473	3-isopropylmalate dehydrogenase activity
LDO91_RS20475	COG0583	DNA-binding transcription factor activity
LDO91_RS20495	COG0789	Transcriptional regulator
LDO91_RS20515	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LDO91_RS20530	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LDO91_RS20545	COG2197	response regulator
LDO91_RS20560	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LDO91_RS20565	COG4585	Histidine kinase
LDO91_RS20595	COG3501	Rhs element vgr protein
LDO91_RS20650	COG3209	COG3209 Rhs family protein
LDO91_RS20665	COG3501	Rhs element vgr protein
LDO91_RS20720	COG3501	Rhs element vgr protein
LDO91_RS20780	COG3829	transcription factor binding
LDO91_RS20810	COG4943	cyclic-guanylate-specific phosphodiesterase activity
LDO91_RS20860	COG1215	transferase activity, transferring glycosyl groups
LDO91_RS20870	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
LDO91_RS20895	COG1215	transferase activity, transferring glycosyl groups
LDO91_RS20905	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
LDO91_RS20915	COG1073	alpha beta
LDO91_RS20930	COG1278	Cold shock
LDO91_RS20955	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LDO91_RS20990	COG3852	Histidine kinase
LDO91_RS20995	COG0583	DNA-binding transcription factor activity
LDO91_RS21015	COG2249	NAD(P)H dehydrogenase (quinone) activity
LDO91_RS21020	COG1357	PFAM Pentapeptide repeats (8 copies)
LDO91_RS21025	COG1028	Short-chain dehydrogenase reductase Sdr
LDO91_RS21030	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
LDO91_RS21035	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
LDO91_RS21045	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LDO91_RS21050	COG2186	Transcriptional regulator
LDO91_RS21100	COG2274	protein secretion by the type I secretion system
LDO91_RS21105	COG0438	transferase activity, transferring glycosyl groups
LDO91_RS21115	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LDO91_RS21130	COG0183	Belongs to the thiolase family
LDO91_RS21135	COG3214	Protein conserved in bacteria
LDO91_RS21140	COG0583	DNA-binding transcription factor activity
LDO91_RS21160	COG0625	glutathione transferase activity
LDO91_RS21170	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
LDO91_RS21200	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LDO91_RS21230	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LDO91_RS21235	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
LDO91_RS21270	COG0024	Methionine aminopeptidase
LDO91_RS21310	COG0058	SHG alpha-glucan phosphorylase activity
LDO91_RS21315	COG1640	4-alpha-glucanotransferase
LDO91_RS21320	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LDO91_RS21325	COG0840	transmembrane signaling receptor activity
LDO91_RS21360	COG3123	guanosine phosphorylase activity
LDO91_RS21370	COG0697	spore germination
LDO91_RS21380	COG5001	Diguanylate cyclase
LDO91_RS21415	COG1054	Belongs to the UPF0176 family
LDO91_RS21445	COG1794	racemase activity, acting on amino acids and derivatives
LDO91_RS21460	COG2329	Antibiotic biosynthesis monooxygenase
LDO91_RS21465	COG0454	-acetyltransferase
LDO91_RS21475	COG2963	transposase activity
LDO91_RS21485	COG0366	Alpha amylase catalytic
LDO91_RS21505	COG3706	GGDEF domain
LDO91_RS21510	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
LDO91_RS21515	COG2204	response regulator
LDO91_RS21545	COG0579	oxidoreductase
LDO91_RS21555	COG0531	amino acid
LDO91_RS21560	COG1522	sequence-specific DNA binding
LDO91_RS21565	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LDO91_RS21590	COG0402	S-adenosylhomocysteine deaminase activity
LDO91_RS21665	COG2267	carboxylic ester hydrolase activity
LDO91_RS21680	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LDO91_RS21740	COG2186	Transcriptional regulator
LDO91_RS21745	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
LDO91_RS21750	COG1309	transcriptional regulator
LDO91_RS21770	COG4266	Belongs to the allantoicase family
LDO91_RS21795	COG1902	pentaerythritol trinitrate reductase activity
LDO91_RS21830	COG5380	lipid catabolic process
LDO91_RS21835	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
LDO91_RS21850	COG0798	PFAM Bile acid sodium symporter
LDO91_RS21860	COG1846	Transcriptional regulator
LDO91_RS21905	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LDO91_RS21910	COG2188	Transcriptional regulator
LDO91_RS21925	COG0395	ABC-type sugar transport system, permease component
LDO91_RS21930	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
LDO91_RS21935	COG3842	ATPase activity
LDO91_RS21940	COG1741	Belongs to the pirin family
LDO91_RS21950	COG0778	Nitroreductase
LDO91_RS21955	COG4191	Histidine kinase
LDO91_RS21985	COG1629	transport
LDO91_RS21985	COG4774	siderophore transport
LDO91_RS21995	COG1021	2,3-dihydroxybenzoate-AMP ligase
LDO91_RS22000	COG0287	Prephenate dehydrogenase
LDO91_RS22000	COG1605	Chorismate mutase
LDO91_RS22015	COG1021	2,3-dihydroxybenzoate-AMP ligase
LDO91_RS22020	COG1169	isochorismate synthase
LDO91_RS22025	COG1028	Short-chain dehydrogenase reductase Sdr
LDO91_RS22030	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LDO91_RS22035	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LDO91_RS22035	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
LDO91_RS22040	COG4592	Periplasmic binding protein
LDO91_RS22045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LDO91_RS22050	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LDO91_RS22060	COG1120	ATPase activity
LDO91_RS22070	COG4667	esterase of the alpha-beta hydrolase superfamily
LDO91_RS22075	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LDO91_RS22105	COG3448	diguanylate cyclase activity
LDO91_RS22105	COG4175	Glycine betaine
LDO91_RS22120	COG2175	clavaminate synthase activity
LDO91_RS22125	COG1280	lysine exporter protein (LysE YggA)
LDO91_RS22135	COG0659	secondary active sulfate transmembrane transporter activity
LDO91_RS22140	COG1085	galactose-1-phosphate uridylyltransferase
LDO91_RS22145	COG1028	Short-chain dehydrogenase reductase Sdr
LDO91_RS22165	COG1028	Short-chain dehydrogenase reductase Sdr
LDO91_RS22185	COG4948	Mandelate Racemase Muconate Lactonizing
LDO91_RS22190	COG2186	Transcriptional regulator
LDO91_RS22235	COG5492	domain, Protein
LDO91_RS22265	COG4964	Belongs to the GSP D family
LDO91_RS22315	COG2885	chlorophyll binding
LDO91_RS22325	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
LDO91_RS22335	COG0561	phosphatase activity
LDO91_RS22350	COG3119	arylsulfatase activity
LDO91_RS22355	COG3119	arylsulfatase activity
LDO91_RS22360	COG0641	radical SAM
LDO91_RS22385	COG0488	(ABC) transporter
LDO91_RS22405	COG3321	synthase
LDO91_RS22405	COG0604	alcohol dehydrogenase
LDO91_RS22405	COG1028	Short-chain dehydrogenase reductase Sdr
LDO91_RS22445	COG1012	belongs to the aldehyde dehydrogenase family
LDO91_RS22450	COG1984	allophanate hydrolase subunit 2
LDO91_RS22455	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
LDO91_RS22460	COG0439	Biotin carboxylase
LDO91_RS22475	COG4214	carbohydrate transport
LDO91_RS22480	COG1129	ABC transporter
LDO91_RS22485	COG1879	ABC-type sugar transport system periplasmic component
LDO91_RS22490	COG0583	DNA-binding transcription factor activity
LDO91_RS22495	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
LDO91_RS22500	COG0574	Belongs to the PEP-utilizing enzyme family
LDO91_RS22500	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LDO91_RS22510	COG1028	Short-chain dehydrogenase reductase Sdr
LDO91_RS22525	COG1172	Belongs to the binding-protein-dependent transport system permease family
LDO91_RS22535	COG4948	Mandelate Racemase Muconate Lactonizing
LDO91_RS22570	COG1122	ATPase activity
LDO91_RS22575	COG4720	Psort location CytoplasmicMembrane, score
LDO91_RS22590	COG1011	Hydrolase
LDO91_RS22605	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LDO91_RS22610	COG4605	iron ion homeostasis
LDO91_RS22615	COG4604	ABC transporter, ATP-binding protein
LDO91_RS22620	COG2375	cellular response to nickel ion
LDO91_RS22635	COG4771	TonB-dependent receptor
LDO91_RS22640	COG4607	ABC-type enterochelin transport system periplasmic component
LDO91_RS22645	COG0110	maltose O-acetyltransferase activity
LDO91_RS22655	COG4681	YaeQ
LDO91_RS22665	COG2204	response regulator
LDO91_RS22670	COG4191	Histidine kinase
LDO91_RS22680	COG2211	Major facilitator Superfamily
LDO91_RS22685	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LDO91_RS22705	COG3437	response regulator, receiver
LDO91_RS22705	COG0784	Response regulator, receiver
LDO91_RS22710	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LDO91_RS22715	COG0814	amino acid
LDO91_RS22720	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
LDO91_RS22725	COG0513	Belongs to the DEAD box helicase family
LDO91_RS22730	COG2067	long-chain fatty acid transport protein
LDO91_RS22740	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
LDO91_RS22750	COG0714	Associated with various cellular activities
LDO91_RS22755	COG2425	protein containing a von Willebrand factor type A (vWA) domain
LDO91_RS22775	COG0366	Alpha amylase catalytic
LDO91_RS22780	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LDO91_RS22790	COG2116	formate transmembrane transporter activity
LDO91_RS22795	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LDO91_RS22795	COG1648	precorrin-2 dehydrogenase activity
LDO91_RS22805	COG0789	Transcriptional regulator
LDO91_RS22830	COG1120	ATPase activity
LDO91_RS22835	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LDO91_RS22840	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LDO91_RS22845	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
LDO91_RS22850	COG3530	Putative quorum-sensing-regulated virulence factor
LDO91_RS22890	COG2015	COG2015, Alkyl sulfatase and related hydrolases
LDO91_RS22895	COG0583	DNA-binding transcription factor activity
LDO91_RS22905	COG4934	collagen metabolic process
LDO91_RS22910	COG0789	Transcriptional regulator
LDO91_RS22925	COG0513	Belongs to the DEAD box helicase family
LDO91_RS22945	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LDO91_RS22950	COG1940	carbohydrate kinase activity
LDO91_RS22955	COG1621	beta-fructofuranosidase activity
LDO91_RS22975	COG0572	uridine kinase
LDO91_RS22985	COG1172	Belongs to the binding-protein-dependent transport system permease family
LDO91_RS22990	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LDO91_RS23000	COG4589	Belongs to the CDS family
LDO91_RS23010	COG0564	pseudouridine synthase activity
LDO91_RS23040	COG1609	Transcriptional regulator
LDO91_RS23045	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LDO91_RS23050	COG3265	gluconokinase activity
LDO91_RS23065	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
LDO91_RS23070	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LDO91_RS23070	COG4191	Histidine kinase
LDO91_RS23080	COG2354	Protein conserved in bacteria
LDO91_RS23090	COG1879	ABC-type sugar transport system periplasmic component
LDO91_RS23100	COG4214	carbohydrate transport
LDO91_RS23110	COG1012	belongs to the aldehyde dehydrogenase family
LDO91_RS23115	COG3734	2-keto-3-deoxy-galactonokinase
LDO91_RS23120	COG0800	Aldolase
LDO91_RS23125	COG4948	Mandelate Racemase Muconate Lactonizing
LDO91_RS23170	COG3338	carbonate dehydratase activity
LDO91_RS23185	COG1879	ABC-type sugar transport system periplasmic component
LDO91_RS23190	COG1129	ABC transporter
LDO91_RS23195	COG1172	Belongs to the binding-protein-dependent transport system permease family
LDO91_RS23200	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LDO91_RS23205	COG1349	DNA-binding transcription factor activity
LDO91_RS23210	COG3447	MASE1 domain protein
LDO91_RS23210	COG5001	Diguanylate cyclase
LDO91_RS23210	COG5002	protein histidine kinase activity
LDO91_RS23220	COG2814	Major facilitator Superfamily
LDO91_RS23230	COG5002	protein histidine kinase activity
LDO91_RS23245	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LDO91_RS23250	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LDO91_RS23260	COG5001	Diguanylate cyclase
LDO91_RS23265	COG2897	thiosulfate sulfurtransferase activity
LDO91_RS23290	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LDO91_RS23300	COG0302	gtp cyclohydrolase
LDO91_RS23305	COG0840	transmembrane signaling receptor activity
LDO91_RS23310	COG0545	Peptidyl-prolyl cis-trans isomerase
LDO91_RS23320	COG2885	chlorophyll binding
LDO91_RS23325	COG2759	Belongs to the formate--tetrahydrofolate ligase family
LDO91_RS23330	COG0668	transmembrane transport
LDO91_RS23350	COG1765	OsmC-like protein
LDO91_RS23380	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LDO91_RS23385	COG5654	RES domain protein
LDO91_RS23405	COG0745	RESPONSE REGULATOR receiver
LDO91_RS23420	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LDO91_RS23435	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
LDO91_RS23440	COG0513	Belongs to the DEAD box helicase family
LDO91_RS23445	COG0625	glutathione transferase activity
LDO91_RS23455	COG0840	transmembrane signaling receptor activity
LDO91_RS23475	COG2824	Alkylphosphonate utilization operon protein PhnA
LDO91_RS23480	COG2267	carboxylic ester hydrolase activity
LDO91_RS23485	COG2067	long-chain fatty acid transport protein
LDO91_RS23495	COG2050	protein possibly involved in aromatic compounds catabolism
LDO91_RS23505	COG4533	DNA binding
LDO91_RS23530	COG0747	negative chemotaxis
LDO91_RS23535	COG0444	Belongs to the ABC transporter superfamily
LDO91_RS23540	COG4608	Belongs to the ABC transporter superfamily
LDO91_RS23545	COG0601	transmembrane transport
LDO91_RS23550	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LDO91_RS23595	COG3118	belongs to the thioredoxin family
LDO91_RS23605	COG4191	Histidine kinase
LDO91_RS23615	COG2271	Major facilitator Superfamily
LDO91_RS23620	COG0469	pyruvate kinase activity
LDO91_RS23625	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LDO91_RS23630	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LDO91_RS23650	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
LDO91_RS23655	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LDO91_RS23660	COG4206	TonB-dependent receptor
LDO91_RS23680	COG0583	DNA-binding transcription factor activity
LDO91_RS23685	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LDO91_RS23685	COG1042	CoA-binding domain protein
LDO91_RS23685	COG0045	succinate-CoA ligase (ADP-forming) activity
LDO91_RS23695	COG1181	Belongs to the D-alanine--D-alanine ligase family
LDO91_RS23710	COG0023	Translation Initiation Factor
LDO91_RS23720	COG3140	Belongs to the UPF0181 family
LDO91_RS23735	COG0745	RESPONSE REGULATOR receiver
LDO91_RS23745	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
LDO91_RS23750	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
LDO91_RS23775	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
LDO91_RS23780	COG2203	Gaf domain
LDO91_RS23780	COG5001	Diguanylate cyclase
LDO91_RS23780	COG4251	negative regulation of phosphorylation
LDO91_RS23780	COG3706	GGDEF domain
LDO91_RS23790	COG2885	chlorophyll binding
LDO91_RS23795	COG0840	transmembrane signaling receptor activity
LDO91_RS23810	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
LDO91_RS23815	COG4149	molybdate abc transporter
LDO91_RS23820	COG1492	cobalamin metabolic process
LDO91_RS23835	COG4067	protein conserved in archaea
LDO91_RS23835	COG0189	ligase activity
LDO91_RS23845	COG0602	queuosine metabolic process
LDO91_RS23850	COG1328	CTP reductase activity
LDO91_RS23870	COG0584	glycerophosphoryl diester phosphodiesterase
LDO91_RS23880	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
LDO91_RS23885	COG3639	organic phosphonate transmembrane transporter activity
LDO91_RS23890	COG3639	organic phosphonate transmembrane transporter activity
LDO91_RS23895	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
LDO91_RS23900	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
LDO91_RS23905	COG4181	ATPase activity
LDO91_RS23915	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
LDO91_RS23920	COG5001	Diguanylate cyclase
LDO91_RS23920	COG1716	ATPase activity
LDO91_RS23930	COG0737	Belongs to the 5'-nucleotidase family
LDO91_RS23935	COG3593	DNA synthesis involved in DNA repair
LDO91_RS23945	COG0583	DNA-binding transcription factor activity
LDO91_RS23950	COG2116	formate transmembrane transporter activity
LDO91_RS23955	COG2353	YceI-like domain
LDO91_RS23960	COG3038	cytochrome b561
LDO91_RS23970	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LDO91_RS23990	COG2200	EAL domain
LDO91_RS24010	COG1129	ABC transporter
LDO91_RS24015	COG1172	Belongs to the binding-protein-dependent transport system permease family
LDO91_RS24020	COG1172	Belongs to the binding-protein-dependent transport system permease family
LDO91_RS24025	COG1879	ABC-type sugar transport system periplasmic component
LDO91_RS24035	COG0459	protein refolding
LDO91_RS24040	COG0508	dehydrogenase complex catalyzes the overall conversion of
LDO91_RS24045	COG1012	belongs to the aldehyde dehydrogenase family
LDO91_RS24050	COG0022	dehydrogenase e1 component
LDO91_RS24055	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LDO91_RS24065	COG1609	Transcriptional regulator
LDO91_RS24075	COG2199	diguanylate cyclase activity
LDO91_RS24075	COG2200	EAL domain
LDO91_RS24075	COG2203	Gaf domain
LDO91_RS24080	COG0523	cobalamin synthesis protein
LDO91_RS24090	COG0156	8-amino-7-oxononanoate synthase activity
LDO91_RS24095	COG0784	Response regulator, receiver
LDO91_RS24095	COG2205	protein histidine kinase activity
LDO91_RS24100	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LDO91_RS24105	COG3300	MHYT domain
LDO91_RS24105	COG5001	Diguanylate cyclase
LDO91_RS24120	COG2154	pterin-4-alpha-carbinolamine dehydratase
LDO91_RS24125	COG0456	acetyltransferase
LDO91_RS24130	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LDO91_RS24135	COG0662	Cupin 2, conserved barrel domain protein
LDO91_RS24140	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
LDO91_RS24180	COG0516	GMP reductase activity
LDO91_RS24185	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LDO91_RS24205	COG2199	diguanylate cyclase activity
LDO91_RS24225	COG0784	Response regulator, receiver
LDO91_RS24225	COG2205	protein histidine kinase activity
LDO91_RS24225	COG2198	Histidine kinase
LDO91_RS24230	COG1879	ABC-type sugar transport system periplasmic component
LDO91_RS24235	COG1803	Methylglyoxal synthase
LDO91_RS24255	COG0210	DNA helicase
LDO91_RS24260	COG1289	transmembrane transporter activity
LDO91_RS24275	COG0861	Integral membrane protein TerC family
LDO91_RS24290	COG1028	Short-chain dehydrogenase reductase Sdr
LDO91_RS24310	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
LDO91_RS24315	COG1063	alcohol dehydrogenase
LDO91_RS24320	COG0156	8-amino-7-oxononanoate synthase activity
LDO91_RS24335	COG0583	DNA-binding transcription factor activity
LDO91_RS24355	COG5001	Diguanylate cyclase
LDO91_RS24360	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
LDO91_RS24365	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
LDO91_RS24395	COG0406	alpha-ribazole phosphatase activity
LDO91_RS24400	COG4191	Histidine kinase
LDO91_RS24410	COG4397	Mu-like prophage major head subunit gpT
LDO91_RS24480	COG2197	response regulator
LDO91_RS24485	COG3850	Histidine kinase
LDO91_RS24490	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LDO91_RS24490	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
LDO91_RS24530	COG0183	Belongs to the thiolase family
LDO91_RS24545	COG2827	Endonuclease containing a URI domain
LDO91_RS24550	COG3132	Protein of unknown function, DUF480
LDO91_RS24555	COG2926	Belongs to the UPF0265 family
LDO91_RS24570	COG0584	glycerophosphoryl diester phosphodiesterase
LDO91_RS24600	COG2205	protein histidine kinase activity
LDO91_RS24600	COG0784	Response regulator, receiver
LDO91_RS24610	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
LDO91_RS24620	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
LDO91_RS24625	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LDO91_RS24630	COG0784	Response regulator, receiver
LDO91_RS24630	COG0835	chemotaxis
LDO91_RS24635	COG1454	alcohol dehydrogenase
LDO91_RS24675	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LDO91_RS24685	COG0633	Ferredoxin
LDO91_RS24685	COG3217	Mosc domain protein beta barrel domain protein
LDO91_RS24685	COG0633	Ferredoxin
LDO91_RS24685	COG3217	Mosc domain protein beta barrel domain protein
LDO91_RS24690	COG0418	dihydroorotase activity
LDO91_RS24700	COG1122	ATPase activity
LDO91_RS24705	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LDO91_RS24710	COG1268	BioY protein
LDO91_RS24725	COG3706	GGDEF domain
LDO91_RS24765	COG0840	transmembrane signaling receptor activity
LDO91_RS24780	COG1609	Transcriptional regulator
LDO91_RS24790	COG1105	Belongs to the carbohydrate kinase PfkB family
LDO91_RS24795	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LDO91_RS24795	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LDO91_RS24795	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
LDO91_RS24800	COG3479	Phenolic acid decarboxylase
LDO91_RS24815	COG0404	The glycine cleavage system catalyzes the degradation of glycine
LDO91_RS24825	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LDO91_RS24830	COG0509	glycine decarboxylation via glycine cleavage system
LDO91_RS24895	COG1917	Cupin 2, conserved barrel domain protein
LDO91_RS24895	COG4977	sequence-specific DNA binding
LDO91_RS24925	COG4771	TonB-dependent receptor
LDO91_RS24930	COG2382	esterase
LDO91_RS24935	COG2130	NADP-dependent
LDO91_RS24965	COG1620	l-lactate permease
LDO91_RS24970	COG1304	FMN binding
LDO91_RS24995	COG1247	-acetyltransferase
LDO91_RS25000	COG0494	nUDIX hydrolase
LDO91_RS25030	COG2818	Glycosylase
LDO91_RS25045	COG0456	acetyltransferase
LDO91_RS25050	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LDO91_RS25065	COG1653	transport
LDO91_RS25075	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LDO91_RS25080	COG3279	Response regulator of the LytR AlgR family
LDO91_RS25085	COG3275	phosphorelay sensor kinase activity
LDO91_RS25105	COG1136	(ABC) transporter
LDO91_RS25105	COG0577	efflux transmembrane transporter activity
LDO91_RS25130	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
LDO91_RS25140	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
LDO91_RS25140	COG2755	lipolytic protein G-D-S-L family
LDO91_RS25180	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LDO91_RS25180	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LDO91_RS25190	COG2814	Major facilitator Superfamily
LDO91_RS25200	COG0673	inositol 2-dehydrogenase activity
LDO91_RS25205	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LDO91_RS25225	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
LDO91_RS25230	COG0840	transmembrane signaling receptor activity
LDO91_RS25245	COG4166	transmembrane transport
LDO91_RS25250	COG4174	ABC transporter (Permease)
LDO91_RS25255	COG4239	(ABC) transporter, permease
LDO91_RS25260	COG4172	Belongs to the ABC transporter superfamily
LDO91_RS25270	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
LDO91_RS25280	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LDO91_RS25285	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LDO91_RS25290	COG1609	Transcriptional regulator
LDO91_RS25370	COG2017	converts alpha-aldose to the beta-anomer
LDO91_RS25375	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LDO91_RS25380	COG1085	galactose-1-phosphate uridylyltransferase
LDO91_RS25385	COG3250	beta-galactosidase activity
LDO91_RS25395	COG0395	ABC-type sugar transport system, permease component
LDO91_RS25400	COG1175	transmembrane transport
LDO91_RS25495	COG0346	lactoylglutathione lyase activity
LDO91_RS25505	COG0346	lactoylglutathione lyase activity
LDO91_RS25520	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
LDO91_RS25525	COG3842	ATPase activity
LDO91_RS25545	COG1609	Transcriptional regulator
LDO91_RS25560	COG0747	negative chemotaxis
LDO91_RS25570	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LDO91_RS25575	COG0444	Belongs to the ABC transporter superfamily
LDO91_RS25580	COG4608	Belongs to the ABC transporter superfamily
LDO91_RS25605	COG1247	-acetyltransferase
LDO91_RS25610	COG0730	response to heat
LDO91_RS25740	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
LDO91_RS25760	COG0527	aspartate kinase activity
LDO91_RS25770	COG3706	GGDEF domain
LDO91_RS25780	COG0840	transmembrane signaling receptor activity
LDO91_RS25990	COG5377	YqaJ viral recombinase family
LDO91_RS26005	COG0582	viral genome integration into host DNA
LDO91_RS26255	COG0179	Fumarylacetoacetate (FAA) hydrolase
LDO91_RS26290	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
LDO91_RS26295	COG0753	catalase activity
LDO91_RS26305	COG5001	Diguanylate cyclase
LDO91_RS26305	COG3300	MHYT domain
LDO91_RS26310	COG1802	Transcriptional regulator
LDO91_RS26315	COG4608	Belongs to the ABC transporter superfamily
LDO91_RS26320	COG0444	Belongs to the ABC transporter superfamily
LDO91_RS26325	COG0601	transmembrane transport
LDO91_RS26330	COG0747	negative chemotaxis
LDO91_RS26385	COG3046	protein related to deoxyribodipyrimidine photolyase
LDO91_RS26410	COG4628	conserved protein (DUF2132)
LDO91_RS26425	COG0251	oxidation-reduction process
LDO91_RS26435	COG0069	glutamate synthase activity
LDO91_RS26465	COG0456	acetyltransferase
LDO91_RS26475	COG1653	transport
LDO91_RS26495	COG3842	ATPase activity
LDO91_RS26510	COG0363	glucosamine-6-phosphate deaminase activity
LDO91_RS26520	COG0513	Belongs to the DEAD box helicase family
LDO91_RS26535	COG1349	DNA-binding transcription factor activity
LDO91_RS26540	COG1349	DNA-binding transcription factor activity
LDO91_RS26550	COG2222	sugar isomerase
LDO91_RS26555	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LDO91_RS26565	COG3716	PTS system mannose fructose sorbose family IID component
LDO91_RS26570	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
LDO91_RS26600	COG0588	phosphoglycerate mutase activity
LDO91_RS26605	COG0640	Transcriptional regulator
LDO91_RS26625	COG0583	DNA-binding transcription factor activity
LDO91_RS26630	COG2124	cytochrome p450
LDO91_RS26640	COG2226	methyltransferase
LDO91_RS26650	COG2501	S4 domain
LDO91_RS26660	COG1280	lysine exporter protein (LysE YggA)
LDO91_RS26685	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
LDO91_RS26710	COG1132	(ABC) transporter
LDO91_RS26730	COG1522	sequence-specific DNA binding
LDO91_RS26735	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
LDO91_RS26750	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
LDO91_RS26755	COG3036	rescue of stalled ribosome
LDO91_RS26785	COG0179	Fumarylacetoacetate (FAA) hydrolase
LDO91_RS26790	COG1846	Transcriptional regulator
LDO91_RS26795	COG0419	ATPase involved in DNA repair
LDO91_RS26800	COG0420	3'-5' exonuclease activity
LDO91_RS26815	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LDO91_RS26855	COG0438	transferase activity, transferring glycosyl groups
LDO91_RS26865	COG5039	Polysaccharide pyruvyl transferase
LDO91_RS26870	COG0463	Glycosyl transferase, family 2
LDO91_RS26870	COG1216	Glycosyl transferase, family 2
LDO91_RS26890	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LDO91_RS26895	COG2197	response regulator
LDO91_RS26910	COG3833	ABC-type maltose transport systems, permease component
LDO91_RS26915	COG1175	transmembrane transport
LDO91_RS26925	COG3842	ATPase activity
LDO91_RS26945	COG0840	transmembrane signaling receptor activity
LDO91_RS26950	COG0714	Associated with various cellular activities
LDO91_RS26970	COG2304	oxidoreductase activity
LDO91_RS26980	COG5002	protein histidine kinase activity
LDO91_RS26980	COG3850	Histidine kinase
LDO91_RS26985	COG0745	RESPONSE REGULATOR receiver
LDO91_RS26990	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LDO91_RS26990	COG4191	Histidine kinase
LDO91_RS26995	COG3437	response regulator, receiver
LDO91_RS26995	COG0784	Response regulator, receiver
LDO91_RS27005	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LDO91_RS27015	COG0109	protoheme IX farnesyltransferase activity
LDO91_RS27020	COG1612	heme a metabolic process
LDO91_RS27045	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
LDO91_RS27050	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LDO91_RS27055	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LDO91_RS27060	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LDO91_RS27070	COG0560	Phosphoserine phosphatase
LDO91_RS27075	COG2197	response regulator
LDO91_RS27085	COG0318	PFAM AMP-dependent synthetase and ligase
LDO91_RS27105	COG2202	Pas domain
LDO91_RS27105	COG2205	protein histidine kinase activity
LDO91_RS27110	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LDO91_RS27115	COG1283	sodium-dependent phosphate transmembrane transporter activity
LDO91_RS27120	COG1126	abc transporter atp-binding protein
LDO91_RS27125	COG0765	amino acid transport
LDO91_RS27130	COG4597	amino acid ABC transporter
LDO91_RS27135	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LDO91_RS27150	COG3842	ATPase activity
LDO91_RS27165	COG1176	ABC-type spermidine putrescine transport system, permease component I
LDO91_RS27230	COG4172	Belongs to the ABC transporter superfamily
LDO91_RS27250	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LDO91_RS27275	COG0346	lactoylglutathione lyase activity
LDO91_RS27280	COG4326	sporulation control protein
LDO91_RS27310	COG0456	acetyltransferase
LDO91_RS27350	COG0583	DNA-binding transcription factor activity
LDO91_RS27355	COG2814	Major facilitator Superfamily
LDO91_RS27375	COG1175	transmembrane transport
LDO91_RS27385	COG1609	Transcriptional regulator
LDO91_RS27395	COG1335	isochorismatase
LDO91_RS27400	COG2249	NAD(P)H dehydrogenase (quinone) activity
LDO91_RS27410	COG1917	Cupin 2, conserved barrel domain protein
LDO91_RS27410	COG4977	sequence-specific DNA binding
LDO91_RS27420	COG0583	DNA-binding transcription factor activity
LDO91_RS27435	COG0583	DNA-binding transcription factor activity
LDO91_RS27440	COG1414	Transcriptional regulator
LDO91_RS27450	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LDO91_RS27455	COG0601	transmembrane transport
LDO91_RS27465	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LDO91_RS27485	COG0515	serine threonine protein kinase
LDO91_RS27485	COG2815	serine threonine protein kinase
LDO91_RS27530	COG1181	Belongs to the D-alanine--D-alanine ligase family
LDO91_RS27605	COG3284	Transcriptional regulator
LDO91_RS27610	COG3842	ATPase activity
LDO91_RS27615	COG3842	ATPase activity
LDO91_RS27625	COG0395	ABC-type sugar transport system, permease component
LDO91_RS27660	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LDO91_RS27720	COG1940	carbohydrate kinase activity
LDO91_RS27730	COG3842	ATPase activity
LDO91_RS27745	COG0076	glutamate decarboxylase activity
LDO91_RS27755	COG4191	Histidine kinase
LDO91_RS27755	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LDO91_RS27765	COG3437	response regulator, receiver
LDO91_RS27765	COG0784	Response regulator, receiver
LDO91_RS27790	COG1770	oligopeptidase
LDO91_RS27805	COG0395	ABC-type sugar transport system, permease component
LDO91_RS27810	COG2723	6-phospho-beta-galactosidase activity
LDO91_RS27815	COG3842	ATPase activity
LDO91_RS27820	COG1609	Transcriptional regulator
LDO91_RS27835	COG0513	Belongs to the DEAD box helicase family
LDO91_RS27845	COG1376	ErfK ybiS ycfS ynhG family protein
LDO91_RS27845	COG1388	LysM domain
LDO91_RS27850	COG0415	Belongs to the DNA photolyase family
LDO91_RS27855	COG0789	Transcriptional regulator
LDO91_RS27860	COG3272	Protein of unknown function (DUF1722)
LDO91_RS27875	COG4214	carbohydrate transport
LDO91_RS27890	COG1609	Transcriptional regulator
LDO91_RS27895	COG0813	purine-nucleoside phosphorylase activity
LDO91_RS27925	COG1566	PFAM secretion protein HlyD family protein
LDO91_RS27935	COG3706	GGDEF domain
LDO91_RS27940	COG0693	protein deglycase activity
LDO91_RS27955	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
LDO91_RS27965	COG1505	serine-type exopeptidase activity
LDO91_RS27985	COG3314	Sporulation integral membrane protein YlbJ
LDO91_RS28020	COG1595	DNA-templated transcription, initiation
LDO91_RS28030	COG1505	serine-type exopeptidase activity
LDO91_RS28035	COG1737	Transcriptional regulator
LDO91_RS28045	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LDO91_RS28055	COG2140	Oxalate decarboxylase
LDO91_RS28060	COG1175	transmembrane transport
LDO91_RS28065	COG0395	ABC-type sugar transport system, permease component
LDO91_RS28075	COG3842	ATPase activity
LDO91_RS28085	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LDO91_RS28095	COG1349	DNA-binding transcription factor activity
LDO91_RS28100	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LDO91_RS28165	COG2207	Transcriptional regulator
LDO91_RS28165	COG1917	Cupin 2, conserved barrel domain protein
LDO91_RS28175	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LDO91_RS28180	COG0363	glucosamine-6-phosphate deaminase activity
LDO91_RS28185	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LDO91_RS28200	COG1278	Cold shock
LDO91_RS28210	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LDO91_RS28215	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LDO91_RS28215	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LDO91_RS28230	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
LDO91_RS28280	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LDO91_RS28285	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LDO91_RS28300	COG4336	lyase activity
LDO91_RS28305	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LDO91_RS28325	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
LDO91_RS28330	COG1984	allophanate hydrolase subunit 2
LDO91_RS28360	COG0840	transmembrane signaling receptor activity
LDO91_RS28365	COG0786	glutamate:sodium symporter activity
LDO91_RS28370	COG2515	1-aminocyclopropane-1-carboxylate deaminase
LDO91_RS28375	COG0583	DNA-binding transcription factor activity
LDO91_RS28380	COG0583	DNA-binding transcription factor activity
LDO91_RS28385	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LDO91_RS28395	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
LDO91_RS28400	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LDO91_RS28460	COG0456	acetyltransferase
LDO91_RS28480	COG2135	peptidase activity
LDO91_RS28485	COG3070	regulator of competence-specific genes
LDO91_RS28495	COG2175	clavaminate synthase activity
LDO91_RS28505	COG1228	amidohydrolase
LDO91_RS28510	COG0840	transmembrane signaling receptor activity
LDO91_RS28520	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LDO91_RS28520	COG2146	nitrite reductase [NAD(P)H] activity
LDO91_RS28525	COG1116	anion transmembrane transporter activity
LDO91_RS28530	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LDO91_RS28545	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LDO91_RS28555	COG0243	molybdopterin cofactor binding
LDO91_RS28570	COG1280	lysine exporter protein (LysE YggA)
LDO91_RS28585	COG1216	Glycosyl transferase, family 2
LDO91_RS28585	COG0463	Glycosyl transferase, family 2
LDO91_RS28610	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LDO91_RS28615	COG3852	Histidine kinase
LDO91_RS28620	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
LDO91_RS28630	COG1609	Transcriptional regulator
LDO91_RS28635	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LDO91_RS28640	COG1879	ABC-type sugar transport system periplasmic component
LDO91_RS28645	COG1172	Belongs to the binding-protein-dependent transport system permease family
LDO91_RS28650	COG1129	ABC transporter
LDO91_RS28655	COG1869	D-ribose catabolic process
LDO91_RS28660	COG0583	DNA-binding transcription factor activity
LDO91_RS28665	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
LDO91_RS28675	COG1280	lysine exporter protein (LysE YggA)
LDO91_RS28695	COG2084	Dehydrogenase
LDO91_RS28735	COG0753	catalase activity
LDO91_RS28750	COG0583	DNA-binding transcription factor activity
LDO91_RS28755	COG0668	transmembrane transport
LDO91_RS28760	COG1418	mRNA catabolic process
LDO91_RS28805	COG2755	lipolytic protein G-D-S-L family
LDO91_RS28835	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
LDO91_RS28855	COG0583	DNA-binding transcription factor activity
LDO91_RS28865	COG0625	glutathione transferase activity
LDO91_RS28880	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LDO91_RS28885	COG0070	glutamate synthase
LDO91_RS28885	COG0069	glutamate synthase activity
LDO91_RS28885	COG0067	glutamate synthase
LDO91_RS28900	COG3706	GGDEF domain
LDO91_RS28910	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LDO91_RS28920	COG0506	proline dehydrogenase activity
LDO91_RS28920	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
LDO91_RS28920	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
LDO91_RS28935	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LDO91_RS28940	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LDO91_RS28945	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LDO91_RS28950	COG1121	(ABC) transporter
LDO91_RS28970	COG0259	pyridoxamine-phosphate oxidase activity
LDO91_RS28990	COG2274	protein secretion by the type I secretion system
LDO91_RS28995	COG1063	alcohol dehydrogenase
LDO91_RS29005	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
LDO91_RS29050	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
LDO91_RS29055	COG0840	transmembrane signaling receptor activity
LDO91_RS29065	COG0835	chemotaxis
LDO91_RS29080	COG0745	RESPONSE REGULATOR receiver
LDO91_RS29090	COG1444	tRNA N-acetyltransferase activity
LDO91_RS29105	COG1192	Involved in chromosome partitioning
LDO91_RS29225	COG3842	ATPase activity
LDO91_RS29450	COG0640	Transcriptional regulator
LDO91_RS29465	COG0786	glutamate:sodium symporter activity
LDO91_RS29595	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
LDO91_RS29615	COG0330	HflC and HflK could
LDO91_RS29635	COG1196	nuclear chromosome segregation
LDO91_RS29725	COG0210	DNA helicase
LDO91_RS29770	COG0633	Ferredoxin
LDO91_RS29840	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LDO91_RS30290	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
LDO91_RS30410	COG1482	cell wall glycoprotein biosynthetic process