locus-tag	class	description
HOS35_gp001	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
HOS35_gp003	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
HOS35_gp007	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HOS35_gp009	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
HOS35_gp010	ENOG4105C9A	Phoh family
HOS35_gp013	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
HOS35_gp035	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
HOS35_gp036	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
HOS35_gp066	ENOG4105MEW	serine threonine protein phosphatase
HOS35_gp072	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
HOS35_gp124	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
HOS35_gp125	ENOG4105C2M	dna polymerase I
HOS35_gp137	ENOG4105C2M	dna polymerase I
HOS35_gp138	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
HOS35_gp141	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
HOS35_gp144	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)