locus-tag	class	description
HOS35_gp001	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HOS35_gp001	COG1328	CTP reductase activity
HOS35_gp007	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HOS35_gp007	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HOS35_gp009	COG0602	queuosine metabolic process
HOS35_gp010	COG1702	phosphate starvation-inducible protein PhoH
HOS35_gp011	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HOS35_gp011	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
HOS35_gp013	COG0328	RNA-DNA hybrid ribonuclease activity
HOS35_gp066	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HOS35_gp072	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HOS35_gp124	COG0756	dUTP diphosphatase activity
HOS35_gp125	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HOS35_gp125	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HOS35_gp138	COG0358	DNA primase activity
HOS35_gp141	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
