locus-tag	class	description
VroAM7_RS00010	COG0592	DNA-directed DNA polymerase activity
VroAM7_RS00020	COG0187	DNA topoisomerase II activity
VroAM7_RS00025	COG0071	Belongs to the small heat shock protein (HSP20) family
VroAM7_RS00030	COG3977	Valine--pyruvate aminotransferase
VroAM7_RS00035	COG0366	Alpha amylase catalytic
VroAM7_RS00050	COG2119	membrane
VroAM7_RS00060	COG0425	Belongs to the sulfur carrier protein TusA family
VroAM7_RS00080	COG0604	alcohol dehydrogenase
VroAM7_RS00085	COG0183	Belongs to the thiolase family
VroAM7_RS00095	COG1739	Uncharacterized protein family UPF0029
VroAM7_RS00100	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
VroAM7_RS00170	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
VroAM7_RS00195	COG0583	DNA-binding transcription factor activity
VroAM7_RS00200	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
VroAM7_RS00205	COG2960	long-chain fatty acid transporting porin activity
VroAM7_RS00215	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
VroAM7_RS00220	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VroAM7_RS00225	COG1309	transcriptional regulator
VroAM7_RS00265	COG0546	phosphoglycolate phosphatase activity
VroAM7_RS00275	COG4172	Belongs to the ABC transporter superfamily
VroAM7_RS00280	COG4166	transmembrane transport
VroAM7_RS00285	COG0601	transmembrane transport
VroAM7_RS00290	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VroAM7_RS00300	COG1609	Transcriptional regulator
VroAM7_RS00305	COG0583	DNA-binding transcription factor activity
VroAM7_RS00310	COG2076	Multidrug Resistance protein
VroAM7_RS00320	COG0129	dihydroxy-acid dehydratase activity
VroAM7_RS00325	COG3265	gluconokinase activity
VroAM7_RS00330	COG2610	gluconate transmembrane transporter activity
VroAM7_RS00335	COG0800	Aldolase
VroAM7_RS00375	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
VroAM7_RS00385	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
VroAM7_RS00400	COG1522	sequence-specific DNA binding
VroAM7_RS00405	COG5001	Diguanylate cyclase
VroAM7_RS00405	COG5002	protein histidine kinase activity
VroAM7_RS00425	COG0589	response to stress
VroAM7_RS00430	COG1528	Iron-storage protein
VroAM7_RS00440	COG2081	HI0933 family
VroAM7_RS00465	COG0464	growth
VroAM7_RS00470	COG1404	Belongs to the peptidase S8 family
VroAM7_RS00545	COG4974	Belongs to the 'phage' integrase family
VroAM7_RS00575	COG1322	Protein conserved in bacteria
VroAM7_RS00585	COG3165	ubiquinone biosynthetic process from chorismate
VroAM7_RS00600	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
VroAM7_RS00605	COG0805	protein transport
VroAM7_RS00615	COG0084	hydrolase, TatD family'
VroAM7_RS00635	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
VroAM7_RS00635	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
VroAM7_RS00645	COG0218	Necessary for normal cell division and for the maintenance of normal septation
VroAM7_RS00675	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
VroAM7_RS00685	COG2204	response regulator
VroAM7_RS00690	COG3852	Histidine kinase
VroAM7_RS00700	COG0174	glutamine synthetase
VroAM7_RS00710	COG1217	gtp-binding protein TYPA
VroAM7_RS00730	COG1490	D-aminoacyl-tRNA deacylase activity
VroAM7_RS00735	COG0456	acetyltransferase
VroAM7_RS00755	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
VroAM7_RS00760	COG3031	protein transport across the cell outer membrane
VroAM7_RS00770	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
VroAM7_RS00775	COG1459	type II secretion system
VroAM7_RS00780	COG2165	general secretion pathway protein
VroAM7_RS00785	COG2165	general secretion pathway protein
VroAM7_RS00790	COG2165	general secretion pathway protein
VroAM7_RS00795	COG4795	General secretion pathway protein
VroAM7_RS00800	COG3156	type II secretion system protein K
VroAM7_RS00805	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
VroAM7_RS00810	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
VroAM7_RS00825	COG1218	3'(2'),5'-bisphosphate nucleotidase
VroAM7_RS00830	COG0494	nUDIX hydrolase
VroAM7_RS00840	COG1040	competence protein
VroAM7_RS00855	COG2183	response to ionizing radiation
VroAM7_RS00865	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
VroAM7_RS00880	COG2233	PERMEase
VroAM7_RS00885	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
VroAM7_RS00890	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
VroAM7_RS00895	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
VroAM7_RS00900	COG1758	RNA polymerase activity
VroAM7_RS00905	COG0194	GDP metabolic process
VroAM7_RS00920	COG0848	biopolymer transport protein
VroAM7_RS00925	COG0811	peptide transport
VroAM7_RS00945	COG4174	ABC transporter (Permease)
VroAM7_RS00950	COG4239	(ABC) transporter, permease
VroAM7_RS00955	COG0747	negative chemotaxis
VroAM7_RS00960	COG0444	Belongs to the ABC transporter superfamily
VroAM7_RS00965	COG4608	Belongs to the ABC transporter superfamily
VroAM7_RS00990	COG2246	polysaccharide biosynthetic process
VroAM7_RS01000	COG1561	YicC-like family, N-terminal region
VroAM7_RS01005	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
VroAM7_RS01010	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
VroAM7_RS01015	COG1560	Kdo2-lipid A biosynthetic process
VroAM7_RS01020	COG1309	transcriptional regulator
VroAM7_RS01025	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
VroAM7_RS01045	COG0227	Belongs to the bacterial ribosomal protein bL28 family
VroAM7_RS01070	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
VroAM7_RS01085	COG0463	Glycosyl transferase, family 2
VroAM7_RS01090	COG0859	PFAM glycosyl transferase family 9
VroAM7_RS01095	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
VroAM7_RS01100	COG3642	lipopolysaccharide core region biosynthetic process
VroAM7_RS01110	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
VroAM7_RS01120	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
VroAM7_RS01145	COG1519	Transferase
VroAM7_RS01150	COG0859	PFAM glycosyl transferase family 9
VroAM7_RS01160	COG1560	Kdo2-lipid A biosynthetic process
VroAM7_RS01170	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VroAM7_RS01205	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
VroAM7_RS01210	COG1459	type II secretion system
VroAM7_RS01250	COG1450	Type ii and iii secretion system protein
VroAM7_RS01270	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
VroAM7_RS01285	COG2089	acid synthase
VroAM7_RS01295	COG1215	transferase activity, transferring glycosyl groups
VroAM7_RS01320	COG0367	asparagine synthase
VroAM7_RS01325	COG0438	transferase activity, transferring glycosyl groups
VroAM7_RS01330	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
VroAM7_RS01340	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
VroAM7_RS01350	COG1215	transferase activity, transferring glycosyl groups
VroAM7_RS01380	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
VroAM7_RS01390	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
VroAM7_RS01405	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
VroAM7_RS01425	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
VroAM7_RS01430	COG0149	triose-phosphate isomerase activity
VroAM7_RS01455	COG1494	fructose-1,6-bisphosphatase
VroAM7_RS01465	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
VroAM7_RS01470	COG1575	Belongs to the MenA family. Type 1 subfamily
VroAM7_RS01490	COG1609	Transcriptional regulator
VroAM7_RS01495	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
VroAM7_RS01520	COG0088	Forms part of the polypeptide exit tunnel
VroAM7_RS01590	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
VroAM7_RS01605	COG1841	ribosomal large subunit assembly
VroAM7_RS01610	COG0200	Binds to the 23S rRNA
VroAM7_RS01615	COG0201	protein transport
VroAM7_RS01620	COG0257	Belongs to the bacterial ribosomal protein bL36 family
VroAM7_RS01625	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
VroAM7_RS01630	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
VroAM7_RS01640	COG0202	RNA polymerase activity
VroAM7_RS01645	COG0203	ribosomal protein L17
VroAM7_RS01655	COG0545	Peptidyl-prolyl cis-trans isomerase
VroAM7_RS01670	COG2153	protein acetylation
VroAM7_RS01675	COG0513	Belongs to the DEAD box helicase family
VroAM7_RS01685	COG0737	Belongs to the 5'-nucleotidase family
VroAM7_RS01690	COG1648	precorrin-2 dehydrogenase activity
VroAM7_RS01690	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
VroAM7_RS01705	COG3273	potassium ion transport
VroAM7_RS01705	COG0471	metal ion transport
VroAM7_RS01710	COG0529	Catalyzes the synthesis of activated sulfate
VroAM7_RS01730	COG1136	(ABC) transporter
VroAM7_RS01745	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
VroAM7_RS01755	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VroAM7_RS01760	COG0729	surface antigen
VroAM7_RS01770	COG2105	PFAM AIG2 family protein
VroAM7_RS01780	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
VroAM7_RS01790	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
VroAM7_RS01795	COG0163	prenyltransferase activity
VroAM7_RS01800	COG4143	(ABC) transporter
VroAM7_RS01805	COG1178	ABC-type Fe3 transport system permease component
VroAM7_RS01810	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
VroAM7_RS01825	COG2358	TRAP transporter, solute receptor (TAXI family
VroAM7_RS01845	COG0142	geranyltranstransferase activity
VroAM7_RS01850	COG0261	This protein binds to 23S rRNA in the presence of protein L20
VroAM7_RS01865	COG2966	Psort location CytoplasmicMembrane, score
VroAM7_RS01870	COG3610	response to peptide
VroAM7_RS01875	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
VroAM7_RS01895	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
VroAM7_RS01900	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
VroAM7_RS01905	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
VroAM7_RS01910	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
VroAM7_RS01930	COG0473	3-isopropylmalate dehydrogenase activity
VroAM7_RS01935	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
VroAM7_RS01960	COG0583	DNA-binding transcription factor activity
VroAM7_RS01965	COG1022	Amp-dependent synthetase and ligase
VroAM7_RS01970	COG0028	Belongs to the TPP enzyme family
VroAM7_RS01975	COG0440	acetolactate synthase activity
VroAM7_RS01980	COG3706	GGDEF domain
VroAM7_RS01990	COG0469	pyruvate kinase activity
VroAM7_RS01995	COG1349	DNA-binding transcription factor activity
VroAM7_RS02000	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
VroAM7_RS02015	COG5002	protein histidine kinase activity
VroAM7_RS02045	COG0358	DNA primase activity
VroAM7_RS02050	COG1610	YqeY-like protein
VroAM7_RS02055	COG0828	Belongs to the bacterial ribosomal protein bS21 family
VroAM7_RS02060	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
VroAM7_RS02065	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
VroAM7_RS02070	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
VroAM7_RS02075	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
VroAM7_RS02080	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
VroAM7_RS02095	COG3267	Type II secretory pathway component ExeA
VroAM7_RS02095	COG3409	Peptidoglycan-binding domain 1 protein
VroAM7_RS02110	COG4991	sh3 domain protein
VroAM7_RS02115	COG0306	phosphate transporter
VroAM7_RS02120	COG1392	Phosphate transport regulator
VroAM7_RS02125	COG3025	triphosphatase activity
VroAM7_RS02130	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
VroAM7_RS02140	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
VroAM7_RS02150	COG1538	Outer membrane efflux protein
VroAM7_RS02155	COG0494	nUDIX hydrolase
VroAM7_RS02160	COG3151	Protein conserved in bacteria
VroAM7_RS02170	COG3150	esterase
VroAM7_RS02180	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
VroAM7_RS02185	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
VroAM7_RS02190	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
VroAM7_RS02195	COG3105	Protein conserved in bacteria
VroAM7_RS02200	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
VroAM7_RS02220	COG0723	plastoquinol--plastocyanin reductase activity
VroAM7_RS02225	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
VroAM7_RS02230	COG2857	Cytochrome c1
VroAM7_RS02235	COG0625	glutathione transferase activity
VroAM7_RS02240	COG2969	positive regulation of protein catabolic process
VroAM7_RS02245	COG2823	Periplasmic or secreted lipoprotein
VroAM7_RS02250	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
VroAM7_RS02265	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
VroAM7_RS02280	COG3116	cell division
VroAM7_RS02285	COG0768	penicillin binding
VroAM7_RS02290	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
VroAM7_RS02295	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
VroAM7_RS02300	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
VroAM7_RS02310	COG0772	Belongs to the SEDS family
VroAM7_RS02325	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
VroAM7_RS02330	COG0849	cell division
VroAM7_RS02335	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
VroAM7_RS02340	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
VroAM7_RS02355	COG0494	nUDIX hydrolase
VroAM7_RS02365	COG0505	Belongs to the CarA family
VroAM7_RS02370	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
VroAM7_RS02385	COG0730	response to heat
VroAM7_RS02390	COG0583	DNA-binding transcription factor activity
VroAM7_RS02395	COG2860	membrane
VroAM7_RS02420	COG0493	'glutamate synthase
VroAM7_RS02425	COG0067	glutamate synthase
VroAM7_RS02425	COG0070	glutamate synthase
VroAM7_RS02425	COG0069	glutamate synthase activity
VroAM7_RS02435	COG0069	glutamate synthase activity
VroAM7_RS02435	COG0067	glutamate synthase
VroAM7_RS02435	COG0070	glutamate synthase
VroAM7_RS02440	COG1242	4 iron, 4 sulfur cluster binding
VroAM7_RS02445	COG5001	Diguanylate cyclase
VroAM7_RS02445	COG3706	GGDEF domain
VroAM7_RS02445	COG4251	negative regulation of phosphorylation
VroAM7_RS02445	COG2203	Gaf domain
VroAM7_RS02450	COG0784	Response regulator, receiver
VroAM7_RS02450	COG2198	Histidine kinase
VroAM7_RS02450	COG5002	protein histidine kinase activity
VroAM7_RS02460	COG0745	RESPONSE REGULATOR receiver
VroAM7_RS02475	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
VroAM7_RS02490	COG0083	homoserine kinase activity
VroAM7_RS02495	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
VroAM7_RS02535	COG1115	amino acid carrier protein
VroAM7_RS02540	COG3022	response to hydroperoxide
VroAM7_RS02555	COG0513	Belongs to the DEAD box helicase family
VroAM7_RS02570	COG0716	FMN binding
VroAM7_RS02575	COG4974	Belongs to the 'phage' integrase family
VroAM7_RS02580	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
VroAM7_RS02585	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
VroAM7_RS02610	COG0667	Aldo Keto reductase
VroAM7_RS02630	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
VroAM7_RS02635	COG0730	response to heat
VroAM7_RS02650	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
VroAM7_RS02670	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
VroAM7_RS02685	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
VroAM7_RS02690	COG0732	type I restriction modification DNA specificity domain
VroAM7_RS02695	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
VroAM7_RS02710	COG2801	Transposase and inactivated derivatives
VroAM7_RS02755	COG1283	sodium-dependent phosphate transmembrane transporter activity
VroAM7_RS02760	COG0583	DNA-binding transcription factor activity
VroAM7_RS02765	COG0640	Transcriptional regulator
VroAM7_RS02770	COG0268	Binds directly to 16S ribosomal RNA
VroAM7_RS02775	COG0728	peptidoglycan biosynthetic process
VroAM7_RS02780	COG0196	riboflavin kinase activity
VroAM7_RS02795	COG1047	Peptidyl-prolyl cis-trans
VroAM7_RS02800	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
VroAM7_RS02805	COG3279	Response regulator of the LytR AlgR family
VroAM7_RS02810	COG3275	phosphorelay sensor kinase activity
VroAM7_RS02815	COG1966	Carbon starvation protein
VroAM7_RS02835	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
VroAM7_RS02845	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
VroAM7_RS02850	COG1605	Chorismate mutase
VroAM7_RS02850	COG0287	Prephenate dehydrogenase
VroAM7_RS02855	COG0739	heme binding
VroAM7_RS02865	COG0488	(ABC) transporter
VroAM7_RS02880	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
VroAM7_RS02885	COG0077	Prephenate dehydratase
VroAM7_RS02885	COG1605	Chorismate mutase
VroAM7_RS02890	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
VroAM7_RS02895	COG0741	lytic transglycosylase activity
VroAM7_RS02900	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VroAM7_RS02905	COG0564	pseudouridine synthase activity
VroAM7_RS02910	COG1496	oxidoreductase activity
VroAM7_RS02915	COG0542	response to heat
VroAM7_RS02970	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
VroAM7_RS03000	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
VroAM7_RS03010	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
VroAM7_RS03015	COG0826	peptidase U32
VroAM7_RS03030	COG0745	RESPONSE REGULATOR receiver
VroAM7_RS03035	COG5002	protein histidine kinase activity
VroAM7_RS03045	COG0248	Ppx GppA phosphatase
VroAM7_RS03050	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
VroAM7_RS03055	COG0573	inorganic phosphate transmembrane transporter activity
VroAM7_RS03060	COG0581	inorganic phosphate transmembrane transporter activity
VroAM7_RS03065	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
VroAM7_RS03070	COG0704	Plays a role in the regulation of phosphate uptake
VroAM7_RS03100	COG0450	alkyl hydroperoxide reductase
VroAM7_RS03105	COG0583	DNA-binding transcription factor activity
VroAM7_RS03110	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
VroAM7_RS03120	COG0517	IMP dehydrogenase activity
VroAM7_RS03145	COG1862	Preprotein translocase
VroAM7_RS03150	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
VroAM7_RS03155	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
VroAM7_RS03160	COG0483	inositol monophosphate 1-phosphatase activity
VroAM7_RS03180	COG0822	iron-sulfur transferase activity
VroAM7_RS03185	COG0316	Belongs to the HesB IscA family
VroAM7_RS03200	COG0633	Ferredoxin
VroAM7_RS03205	COG2975	iron-sulfur cluster assembly
VroAM7_RS03240	COG2976	Protein conserved in bacteria
VroAM7_RS03245	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VroAM7_RS03260	COG2203	Gaf domain
VroAM7_RS03260	COG2199	diguanylate cyclase activity
VroAM7_RS03275	COG0516	GMP reductase activity
VroAM7_RS03275	COG0517	IMP dehydrogenase activity
VroAM7_RS03285	COG1757	Na H antiporter
VroAM7_RS03295	COG1584	GPR1 FUN34 yaaH family protein
VroAM7_RS03300	COG1115	amino acid carrier protein
VroAM7_RS03310	COG0583	DNA-binding transcription factor activity
VroAM7_RS03320	COG2873	o-acetylhomoserine
VroAM7_RS03325	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
VroAM7_RS03350	COG1289	transmembrane transporter activity
VroAM7_RS03355	COG0583	DNA-binding transcription factor activity
VroAM7_RS03370	COG2867	negative regulation of translational initiation
VroAM7_RS03375	COG2914	Belongs to the UPF0125 (RnfH) family
VroAM7_RS03380	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VroAM7_RS03390	COG0497	DNA recombination
VroAM7_RS03410	COG1301	dicarboxylic acid transport
VroAM7_RS03455	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
VroAM7_RS03460	COG0590	tRNA wobble adenosine to inosine editing
VroAM7_RS03475	COG0047	phosphoribosylformylglycinamidine synthase activity
VroAM7_RS03475	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
VroAM7_RS03495	COG2195	Cleaves the N-terminal amino acid of tripeptides
VroAM7_RS03500	COG2252	PERMEase
VroAM7_RS03510	COG1073	alpha beta
VroAM7_RS03525	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
VroAM7_RS03530	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
VroAM7_RS03535	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
VroAM7_RS03535	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
VroAM7_RS03560	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
VroAM7_RS03565	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
VroAM7_RS03575	COG0142	geranyltranstransferase activity
VroAM7_RS03585	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
VroAM7_RS03600	COG0583	DNA-binding transcription factor activity
VroAM7_RS03610	COG2363	Small membrane protein
VroAM7_RS03625	COG1611	Belongs to the LOG family
VroAM7_RS03650	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
VroAM7_RS03655	COG0737	Belongs to the 5'-nucleotidase family
VroAM7_RS03665	COG1464	Belongs to the NlpA lipoprotein family
VroAM7_RS03670	COG2011	ABC-type metal ion transport system permease component
VroAM7_RS03675	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
VroAM7_RS03680	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
VroAM7_RS03690	COG1263	PTS System
VroAM7_RS03690	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VroAM7_RS03695	COG0366	Alpha amylase catalytic
VroAM7_RS03700	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
VroAM7_RS03705	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
VroAM7_RS03725	COG1686	Belongs to the peptidase S11 family
VroAM7_RS03730	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
VroAM7_RS03735	COG0772	Belongs to the SEDS family
VroAM7_RS03740	COG0768	penicillin binding
VroAM7_RS03750	COG0799	negative regulation of ribosome biogenesis
VroAM7_RS03755	COG1466	dna polymerase III delta subunit
VroAM7_RS03760	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
VroAM7_RS03770	COG2888	peptidyl-tyrosine sulfation
VroAM7_RS03775	COG0815	Transfers the fatty acyl group on membrane lipoproteins
VroAM7_RS03780	COG4535	Mg2 and Co2 transporter CorC
VroAM7_RS03790	COG1702	phosphate starvation-inducible protein PhoH
VroAM7_RS03805	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VroAM7_RS03930	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
VroAM7_RS03955	COG2890	protein-(glutamine-N5) methyltransferase activity
VroAM7_RS03960	COG3094	Invasion gene expression up-regulator, SirB
VroAM7_RS03965	COG2912	Transglutaminase-like superfamily
VroAM7_RS03975	COG0737	Belongs to the 5'-nucleotidase family
VroAM7_RS03980	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
VroAM7_RS03985	COG1187	pseudouridine synthase activity
VroAM7_RS03990	COG2840	Smr protein MutS2
VroAM7_RS04040	COG2608	mercury ion transmembrane transporter activity
VroAM7_RS04040	COG2217	Heavy metal translocating P-type atpase
VroAM7_RS04095	COG2747	anti-sigma28 factor FlgM
VroAM7_RS04105	COG0835	chemotaxis
VroAM7_RS04105	COG0784	Response regulator, receiver
VroAM7_RS04110	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
VroAM7_RS04115	COG1815	bacterial-type flagellum-dependent cell motility
VroAM7_RS04120	COG1558	bacterial-type flagellum-dependent cell motility
VroAM7_RS04130	COG1749	Flagellar hook protein flgE
VroAM7_RS04135	COG4787	bacterial-type flagellum-dependent cell motility
VroAM7_RS04145	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
VroAM7_RS04150	COG1706	bacterial-type flagellum-dependent cell motility
VroAM7_RS04155	COG3951	Flagellar rod assembly protein muramidase FlgJ
VroAM7_RS04155	COG1705	Flagellar rod assembly protein muramidase FlgJ
VroAM7_RS04170	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VroAM7_RS04180	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VroAM7_RS04185	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VroAM7_RS04190	COG2190	(PTS) system
VroAM7_RS04195	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
VroAM7_RS04200	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
VroAM7_RS04210	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
VroAM7_RS04215	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
VroAM7_RS04245	COG0330	HflC and HflK could
VroAM7_RS04250	COG2194	sulfuric ester hydrolase activity
VroAM7_RS04270	COG1215	transferase activity, transferring glycosyl groups
VroAM7_RS04275	COG1215	transferase activity, transferring glycosyl groups
VroAM7_RS04280	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
VroAM7_RS04285	COG0457	Tetratricopeptide repeat
VroAM7_RS04285	COG3118	belongs to the thioredoxin family
VroAM7_RS04290	COG3118	belongs to the thioredoxin family
VroAM7_RS04300	COG0300	oxidoreductase activity
VroAM7_RS04305	COG1090	epimerase
VroAM7_RS04335	COG0622	Phosphoesterase
VroAM7_RS04355	COG3710	Transcriptional regulator
VroAM7_RS04370	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
VroAM7_RS04375	COG3104	oligopeptide transport
VroAM7_RS04380	COG0250	Participates in transcription elongation, termination and antitermination
VroAM7_RS04385	COG0367	asparagine synthase
VroAM7_RS04390	COG4651	solute:proton antiporter activity
VroAM7_RS04390	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
VroAM7_RS04395	COG1940	carbohydrate kinase activity
VroAM7_RS04395	COG1846	Transcriptional regulator
VroAM7_RS04400	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
VroAM7_RS04410	COG2190	(PTS) system
VroAM7_RS04410	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VroAM7_RS04410	COG1263	PTS System
VroAM7_RS04425	COG0735	belongs to the Fur family
VroAM7_RS04445	COG0596	Alpha beta hydrolase
VroAM7_RS04450	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
VroAM7_RS04455	COG0033	Phosphoglucomutase
VroAM7_RS04465	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
VroAM7_RS04480	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
VroAM7_RS04485	COG1053	succinate dehydrogenase
VroAM7_RS04495	COG0567	Dehydrogenase, E1 component
VroAM7_RS04500	COG0508	dehydrogenase complex catalyzes the overall conversion of
VroAM7_RS04515	COG1108	ABC-type Mn2 Zn2 transport systems permease components
VroAM7_RS04520	COG1121	(ABC) transporter
VroAM7_RS04525	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
VroAM7_RS04535	COG1918	ferrous iron import across plasma membrane
VroAM7_RS04570	COG3102	Protein conserved in bacteria
VroAM7_RS04575	COG0788	formyltetrahydrofolate deformylase activity
VroAM7_RS04585	COG1199	ATP-dependent helicase activity
VroAM7_RS04590	COG1214	PFAM Peptidase M22, glycoprotease
VroAM7_RS04605	COG2267	carboxylic ester hydrolase activity
VroAM7_RS04610	COG0318	PFAM AMP-dependent synthetase and ligase
VroAM7_RS04615	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
VroAM7_RS04620	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
VroAM7_RS04625	COG2894	cell division
VroAM7_RS04635	COG3100	YcgL domain-containing protein
VroAM7_RS04640	COG2951	lytic endotransglycosylase activity
VroAM7_RS04650	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
VroAM7_RS04655	COG2852	Protein conserved in bacteria
VroAM7_RS04670	COG4974	Belongs to the 'phage' integrase family
VroAM7_RS04700	COG1028	Short-chain dehydrogenase reductase Sdr
VroAM7_RS04735	COG2986	histidine ammonia-lyase
VroAM7_RS04740	COG1216	Glycosyl transferase, family 2
VroAM7_RS04760	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
VroAM7_RS04765	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
VroAM7_RS04795	COG2226	methyltransferase
VroAM7_RS04880	COG1181	Belongs to the D-alanine--D-alanine ligase family
VroAM7_RS04900	COG1716	ATPase activity
VroAM7_RS04925	COG4991	sh3 domain protein
VroAM7_RS04925	COG0515	serine threonine protein kinase
VroAM7_RS04925	COG3064	Membrane
VroAM7_RS04935	COG2169	Transcriptional regulator
VroAM7_RS04940	COG1253	flavin adenine dinucleotide binding
VroAM7_RS04945	COG0513	Belongs to the DEAD box helicase family
VroAM7_RS04950	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
VroAM7_RS04955	COG0569	domain protein
VroAM7_RS04960	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
VroAM7_RS04975	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
VroAM7_RS04980	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
VroAM7_RS04985	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
VroAM7_RS05020	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
VroAM7_RS05025	COG0776	regulation of translation
VroAM7_RS05030	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
VroAM7_RS05035	COG1555	photosystem II stabilization
VroAM7_RS05055	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
VroAM7_RS05060	COG0436	Aminotransferase
VroAM7_RS05065	COG1169	isochorismate synthase
VroAM7_RS05075	COG0596	Alpha beta hydrolase
VroAM7_RS05080	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
VroAM7_RS05100	COG2855	membrane
VroAM7_RS05160	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
VroAM7_RS05185	COG1522	sequence-specific DNA binding
VroAM7_RS05195	COG1946	Acyl-CoA thioesterase
VroAM7_RS05200	COG3126	Type III secretion system lipoprotein chaperone (YscW)
VroAM7_RS05225	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
VroAM7_RS05230	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
VroAM7_RS05235	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
VroAM7_RS05240	COG0517	IMP dehydrogenase activity
VroAM7_RS05240	COG0617	tRNA 3'-terminal CCA addition
VroAM7_RS05240	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
VroAM7_RS05250	COG2217	Heavy metal translocating P-type atpase
VroAM7_RS05270	COG0537	adenosine 5'-monophosphoramidase activity
VroAM7_RS05305	COG1252	NADH dehydrogenase
VroAM7_RS05310	COG3385	transposase activity
VroAM7_RS05325	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
VroAM7_RS05335	COG4591	ABC-type transport system involved in lipoprotein release permease component
VroAM7_RS05340	COG1136	(ABC) transporter
VroAM7_RS05345	COG4591	ABC-type transport system involved in lipoprotein release permease component
VroAM7_RS05355	COG0658	competence protein
VroAM7_RS05355	COG2333	competence protein COMEC
VroAM7_RS05360	COG1132	(ABC) transporter
VroAM7_RS05380	COG2719	SpoVR family
VroAM7_RS05385	COG2718	Belongs to the UPF0229 family
VroAM7_RS05390	COG2766	serine protein kinase
VroAM7_RS05410	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
VroAM7_RS05420	COG1882	Formate acetyltransferase
VroAM7_RS05455	COG0708	Exodeoxyribonuclease III
VroAM7_RS05465	COG3923	Primosomal replication protein n
VroAM7_RS05470	COG0730	response to heat
VroAM7_RS05475	COG1199	ATP-dependent helicase activity
VroAM7_RS05485	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
VroAM7_RS05490	COG1187	pseudouridine synthase activity
VroAM7_RS05500	COG1278	Cold shock
VroAM7_RS05510	COG0542	response to heat
VroAM7_RS05520	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
VroAM7_RS05550	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
VroAM7_RS05560	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
VroAM7_RS05565	COG0297	glycogen (starch) synthase activity
VroAM7_RS05585	COG3070	regulator of competence-specific genes
VroAM7_RS05600	COG0745	RESPONSE REGULATOR receiver
VroAM7_RS05605	COG1434	Gram-negative-bacterium-type cell wall biogenesis
VroAM7_RS05610	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
VroAM7_RS05620	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
VroAM7_RS05625	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
VroAM7_RS05640	COG4067	protein conserved in archaea
VroAM7_RS05640	COG0189	ligase activity
VroAM7_RS05660	COG1801	Protein of unknown function DUF72
VroAM7_RS05670	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
VroAM7_RS05675	COG0840	transmembrane signaling receptor activity
VroAM7_RS05680	COG0632	four-way junction helicase activity
VroAM7_RS05690	COG1271	oxidase subunit
VroAM7_RS05695	COG1294	oxidase, subunit
VroAM7_RS05700	COG4890	Cyd operon protein YbgT
VroAM7_RS05710	COG0824	Thioesterase
VroAM7_RS05715	COG0811	peptide transport
VroAM7_RS05730	COG0823	Involved in the tonB-independent uptake of proteins
VroAM7_RS05735	COG2885	chlorophyll binding
VroAM7_RS05740	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
VroAM7_RS05755	COG3766	membrane
VroAM7_RS05765	COG0754	glutathionylspermidine amidase activity
VroAM7_RS05780	COG1858	cytochrome C peroxidase
VroAM7_RS05800	COG5002	protein histidine kinase activity
VroAM7_RS05800	COG0784	Response regulator, receiver
VroAM7_RS05825	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
VroAM7_RS05830	COG0732	type I restriction modification DNA specificity domain
VroAM7_RS05840	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
VroAM7_RS05845	COG1401	restriction endodeoxyribonuclease activity
VroAM7_RS05855	COG1620	l-lactate permease
VroAM7_RS05860	COG0247	lactate metabolic process
VroAM7_RS05865	COG1139	Iron-sulfur cluster binding protein
VroAM7_RS05870	COG1556	Lactate utilization protein
VroAM7_RS05875	COG0583	DNA-binding transcription factor activity
VroAM7_RS05885	COG2824	Alkylphosphonate utilization operon protein PhnA
VroAM7_RS05915	COG1136	(ABC) transporter
VroAM7_RS05950	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VroAM7_RS05955	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
VroAM7_RS05985	COG0840	transmembrane signaling receptor activity
VroAM7_RS06010	COG3009	Protein conserved in bacteria
VroAM7_RS06015	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
VroAM7_RS06015	COG3008	intermembrane lipid transfer
VroAM7_RS06020	COG2995	paraquat-inducible protein a
VroAM7_RS06025	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
VroAM7_RS06040	COG4232	protein-disulfide reductase activity
VroAM7_RS06045	COG3118	belongs to the thioredoxin family
VroAM7_RS06050	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
VroAM7_RS06075	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VroAM7_RS06085	COG0577	efflux transmembrane transporter activity
VroAM7_RS06085	COG1136	(ABC) transporter
VroAM7_RS06090	COG0577	efflux transmembrane transporter activity
VroAM7_RS06090	COG1136	(ABC) transporter
VroAM7_RS06095	COG0577	efflux transmembrane transporter activity
VroAM7_RS06095	COG1136	(ABC) transporter
VroAM7_RS06100	COG2176	DNA-directed DNA polymerase activity
VroAM7_RS06155	COG1172	Belongs to the binding-protein-dependent transport system permease family
VroAM7_RS06160	COG1172	Belongs to the binding-protein-dependent transport system permease family
VroAM7_RS06165	COG1129	ABC transporter
VroAM7_RS06200	COG5002	protein histidine kinase activity
VroAM7_RS06200	COG3850	Histidine kinase
VroAM7_RS06205	COG0745	RESPONSE REGULATOR receiver
VroAM7_RS06210	COG0463	Glycosyl transferase, family 2
VroAM7_RS06215	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
VroAM7_RS06225	COG2964	Protein conserved in bacteria
VroAM7_RS06240	COG0446	pyridine nucleotide-disulphide oxidoreductase
VroAM7_RS06245	COG1032	radical SAM domain protein
VroAM7_RS06250	COG2203	Gaf domain
VroAM7_RS06250	COG3706	GGDEF domain
VroAM7_RS06250	COG4251	negative regulation of phosphorylation
VroAM7_RS06250	COG5001	Diguanylate cyclase
VroAM7_RS06280	COG2350	Protein conserved in bacteria
VroAM7_RS06285	COG1607	acyl-coa hydrolase
VroAM7_RS06310	COG1301	dicarboxylic acid transport
VroAM7_RS06315	COG0159	tryptophan synthase activity
VroAM7_RS06325	COG0135	phosphoribosylanthranilate isomerase activity
VroAM7_RS06325	COG0134	indole-3-glycerol-phosphate synthase activity
VroAM7_RS06335	COG0512	Glutamine amidotransferase of anthranilate synthase
VroAM7_RS06340	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
VroAM7_RS06350	COG0613	PHP domain protein
VroAM7_RS06355	COG0009	L-threonylcarbamoyladenylate synthase
VroAM7_RS06365	COG1187	pseudouridine synthase activity
VroAM7_RS06385	COG0417	DNA replication proofreading
VroAM7_RS06400	COG2197	response regulator
VroAM7_RS06405	COG0322	excinuclease ABC activity
VroAM7_RS06445	COG0019	diaminopimelate decarboxylase activity
VroAM7_RS06475	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
VroAM7_RS06480	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
VroAM7_RS06490	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
VroAM7_RS06510	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
VroAM7_RS06520	COG0437	4 iron, 4 sulfur cluster binding
VroAM7_RS06525	COG3301	Polysulphide reductase, NrfD
VroAM7_RS06530	COG1138	Cytochrome C-type biogenesis protein
VroAM7_RS06535	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
VroAM7_RS06540	COG3088	subunit of a heme lyase
VroAM7_RS06540	COG4235	cytochrome complex assembly
VroAM7_RS06550	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
VroAM7_RS06575	COG2989	Protein conserved in bacteria
VroAM7_RS06580	COG3108	Peptidase M15
VroAM7_RS06605	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
VroAM7_RS06630	COG1846	Transcriptional regulator
VroAM7_RS06635	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
VroAM7_RS06640	COG0840	transmembrane signaling receptor activity
VroAM7_RS06660	COG1448	Aminotransferase
VroAM7_RS06665	COG2770	Histidine kinase
VroAM7_RS06665	COG3437	response regulator, receiver
VroAM7_RS06680	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
VroAM7_RS06695	COG0017	Asparaginyl-tRNA synthetase
VroAM7_RS06700	COG0840	transmembrane signaling receptor activity
VroAM7_RS06705	COG0720	synthase
VroAM7_RS06710	COG0531	amino acid
VroAM7_RS06715	COG1280	lysine exporter protein (LysE YggA)
VroAM7_RS06720	COG1560	Kdo2-lipid A biosynthetic process
VroAM7_RS06725	COG0471	metal ion transport
VroAM7_RS06730	COG4191	Histidine kinase
VroAM7_RS06730	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VroAM7_RS06740	COG3706	GGDEF domain
VroAM7_RS06745	COG5001	Diguanylate cyclase
VroAM7_RS06755	COG1280	lysine exporter protein (LysE YggA)
VroAM7_RS06760	COG1328	CTP reductase activity
VroAM7_RS06765	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
VroAM7_RS06785	COG0861	Integral membrane protein TerC family
VroAM7_RS06795	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
VroAM7_RS06800	COG4221	oxidoreductase activity
VroAM7_RS06805	COG3706	GGDEF domain
VroAM7_RS06815	COG1454	alcohol dehydrogenase
VroAM7_RS06820	COG0814	amino acid
VroAM7_RS06835	COG1120	ATPase activity
VroAM7_RS06840	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
VroAM7_RS06845	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VroAM7_RS06850	COG4774	siderophore transport
VroAM7_RS06860	COG1132	(ABC) transporter
VroAM7_RS06865	COG1132	(ABC) transporter
VroAM7_RS06875	COG0583	DNA-binding transcription factor activity
VroAM7_RS06880	COG0583	DNA-binding transcription factor activity
VroAM7_RS06960	COG1368	sulfuric ester hydrolase activity
VroAM7_RS06965	COG0215	cysteine-tRNA ligase activity
VroAM7_RS06970	COG0534	Mate efflux family protein
VroAM7_RS06975	COG2113	Glycine betaine
VroAM7_RS06980	COG4176	ABC-type proline glycine betaine transport system permease component
VroAM7_RS06990	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
VroAM7_RS07000	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
VroAM7_RS07005	COG0456	acetyltransferase
VroAM7_RS07010	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
VroAM7_RS07015	COG0662	Cupin 2, conserved barrel domain protein
VroAM7_RS07020	COG0527	aspartate kinase activity
VroAM7_RS07030	COG1858	cytochrome C peroxidase
VroAM7_RS07055	COG0583	DNA-binding transcription factor activity
VroAM7_RS07080	COG0443	Heat shock 70 kDa protein
VroAM7_RS07085	COG0443	Heat shock 70 kDa protein
VroAM7_RS07095	COG2199	diguanylate cyclase activity
VroAM7_RS07135	COG0243	molybdopterin cofactor binding
VroAM7_RS07140	COG0437	4 iron, 4 sulfur cluster binding
VroAM7_RS07145	COG3302	dmso reductase anchor subunit
VroAM7_RS07150	COG3381	protein complex oligomerization
VroAM7_RS07160	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
VroAM7_RS07165	COG1643	Atp-dependent helicase
VroAM7_RS07180	COG0813	purine-nucleoside phosphorylase activity
VroAM7_RS07205	COG2195	Cleaves the N-terminal amino acid of tripeptides
VroAM7_RS07245	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
VroAM7_RS07250	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
VroAM7_RS07255	COG2909	trisaccharide binding
VroAM7_RS07290	COG1280	lysine exporter protein (LysE YggA)
VroAM7_RS07300	COG1115	amino acid carrier protein
VroAM7_RS07325	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
VroAM7_RS07340	COG0625	glutathione transferase activity
VroAM7_RS07345	COG1028	Short-chain dehydrogenase reductase Sdr
VroAM7_RS07375	COG0589	response to stress
VroAM7_RS07380	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
VroAM7_RS07385	COG0668	transmembrane transport
VroAM7_RS07390	COG3247	response to pH
VroAM7_RS07400	COG1846	Transcriptional regulator
VroAM7_RS07420	COG0110	maltose O-acetyltransferase activity
VroAM7_RS07440	COG2205	protein histidine kinase activity
VroAM7_RS07440	COG4999	Histidine kinase
VroAM7_RS07440	COG3437	response regulator, receiver
VroAM7_RS07440	COG3850	Histidine kinase
VroAM7_RS07450	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
VroAM7_RS07455	COG1215	transferase activity, transferring glycosyl groups
VroAM7_RS07460	COG0438	transferase activity, transferring glycosyl groups
VroAM7_RS07470	COG0438	transferase activity, transferring glycosyl groups
VroAM7_RS07490	COG0438	transferase activity, transferring glycosyl groups
VroAM7_RS07500	COG2204	response regulator
VroAM7_RS07530	COG1793	dna ligase
VroAM7_RS07540	COG0534	Mate efflux family protein
VroAM7_RS07545	COG0307	riboflavin synthase, alpha
VroAM7_RS07555	COG3001	Fructosamine kinase
VroAM7_RS07560	COG2201	protein-glutamate methylesterase activity
VroAM7_RS07565	COG3706	GGDEF domain
VroAM7_RS07575	COG0791	NLP P60 protein
VroAM7_RS07580	COG0840	transmembrane signaling receptor activity
VroAM7_RS07585	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
VroAM7_RS07585	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
VroAM7_RS07590	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
VroAM7_RS07605	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
VroAM7_RS07610	COG0372	Belongs to the citrate synthase family
VroAM7_RS07620	COG2828	Protein conserved in bacteria
VroAM7_RS07645	COG0561	phosphatase activity
VroAM7_RS07650	COG0602	queuosine metabolic process
VroAM7_RS07660	COG3706	GGDEF domain
VroAM7_RS07685	COG3047	cAMP biosynthetic process
VroAM7_RS07685	COG2885	chlorophyll binding
VroAM7_RS07710	COG0840	transmembrane signaling receptor activity
VroAM7_RS07715	COG1254	Belongs to the acylphosphatase family
VroAM7_RS07720	COG2920	part of a sulfur-relay system
VroAM7_RS07725	COG0670	Belongs to the BI1 family
VroAM7_RS07730	COG1126	abc transporter atp-binding protein
VroAM7_RS07735	COG0765	amino acid transport
VroAM7_RS07740	COG4597	amino acid ABC transporter
VroAM7_RS07745	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VroAM7_RS07765	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
VroAM7_RS07795	COG3008	intermembrane lipid transfer
VroAM7_RS07800	COG2995	paraquat-inducible protein a
VroAM7_RS07805	COG1132	(ABC) transporter
VroAM7_RS07810	COG1956	GAF domain-containing protein
VroAM7_RS07815	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
VroAM7_RS07830	COG0308	aminopeptidase N
VroAM7_RS07840	COG2902	Dehydrogenase
VroAM7_RS07865	COG0488	(ABC) transporter
VroAM7_RS07880	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
VroAM7_RS07885	COG1067	ATP-dependent peptidase activity
VroAM7_RS07915	COG0784	Response regulator, receiver
VroAM7_RS07915	COG2205	protein histidine kinase activity
VroAM7_RS07930	COG3278	Belongs to the heme-copper respiratory oxidase family
VroAM7_RS07945	COG2010	Cytochrome c
VroAM7_RS07955	COG2217	Heavy metal translocating P-type atpase
VroAM7_RS07970	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
VroAM7_RS07975	COG0589	response to stress
VroAM7_RS08000	COG3842	ATPase activity
VroAM7_RS08010	COG1177	transmembrane transport
VroAM7_RS08020	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
VroAM7_RS08025	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
VroAM7_RS08050	COG3209	COG3209 Rhs family protein
VroAM7_RS08065	COG0437	4 iron, 4 sulfur cluster binding
VroAM7_RS08070	COG0243	molybdopterin cofactor binding
VroAM7_RS08070	COG3383	formate dehydrogenase (NAD+) activity
VroAM7_RS08080	COG3381	protein complex oligomerization
VroAM7_RS08100	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
VroAM7_RS08125	COG0488	(ABC) transporter
VroAM7_RS08145	COG4191	Histidine kinase
VroAM7_RS08150	COG2204	response regulator
VroAM7_RS08160	COG4662	Binding-protein-dependent transport system inner membrane component
VroAM7_RS08165	COG3842	ATPase activity
VroAM7_RS08175	COG0303	'Molybdopterin
VroAM7_RS08190	COG1940	carbohydrate kinase activity
VroAM7_RS08195	COG3148	PFAM DTW domain containing protein
VroAM7_RS08260	COG0730	response to heat
VroAM7_RS08265	COG0840	transmembrane signaling receptor activity
VroAM7_RS08270	COG2358	TRAP transporter, solute receptor (TAXI family
VroAM7_RS08275	COG3437	response regulator, receiver
VroAM7_RS08280	COG1012	belongs to the aldehyde dehydrogenase family
VroAM7_RS08285	COG3284	Transcriptional regulator
VroAM7_RS08315	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
VroAM7_RS08320	COG0363	glucosamine-6-phosphate deaminase activity
VroAM7_RS08325	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
VroAM7_RS08335	COG4774	siderophore transport
VroAM7_RS08340	COG4565	transcriptional regulatory protein
VroAM7_RS08345	COG3290	protein histidine kinase activity
VroAM7_RS08365	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VroAM7_RS08380	COG1320	monovalent cation:proton antiporter activity
VroAM7_RS08385	COG2212	antiporter activity
VroAM7_RS08390	COG1863	multisubunit Na H antiporter MnhE subunit
VroAM7_RS08395	COG0651	ATP synthesis coupled electron transport
VroAM7_RS08400	COG1006	Multisubunit Na H antiporter MnhC subunit
VroAM7_RS08405	COG2111	Na H antiporter
VroAM7_RS08405	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
VroAM7_RS08415	COG0589	response to stress
VroAM7_RS08500	COG4245	von Willebrand factor, type A
VroAM7_RS08505	COG3335	DDE superfamily endonuclease
VroAM7_RS08525	COG0494	nUDIX hydrolase
VroAM7_RS08905	COG0681	Belongs to the peptidase S26 family
VroAM7_RS09000	COG2026	Addiction module toxin, RelE StbE family
VroAM7_RS09040	COG0242	peptide deformylase activity
VroAM7_RS09180	COG2314	TM2 domain
VroAM7_RS09200	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VroAM7_RS09215	COG3106	COG3106 Predicted ATPase
VroAM7_RS09230	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
VroAM7_RS09235	COG2205	protein histidine kinase activity
VroAM7_RS09235	COG2198	Histidine kinase
VroAM7_RS09235	COG0784	Response regulator, receiver
VroAM7_RS09245	COG0494	nUDIX hydrolase
VroAM7_RS09250	COG0814	amino acid
VroAM7_RS09255	COG1760	l-serine dehydratase
VroAM7_RS09265	COG5001	Diguanylate cyclase
VroAM7_RS09265	COG3300	MHYT domain
VroAM7_RS09275	COG2197	response regulator
VroAM7_RS09290	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
VroAM7_RS09295	COG3063	Type IV pilus biogenesis stability protein PilW
VroAM7_RS09320	COG1451	nucleotide metabolic process
VroAM7_RS09325	COG3475	LICD family
VroAM7_RS09330	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
VroAM7_RS09335	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
VroAM7_RS09355	COG1566	PFAM secretion protein HlyD family protein
VroAM7_RS09365	COG0583	DNA-binding transcription factor activity
VroAM7_RS09400	COG4139	cobalamin transport
VroAM7_RS09425	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
VroAM7_RS09435	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
VroAM7_RS09440	COG0702	epimerase
VroAM7_RS09445	COG2925	Exonuclease
VroAM7_RS09455	COG1346	cytolysis
VroAM7_RS09500	COG0072	phenylalanine-tRNA ligase activity
VroAM7_RS09500	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
VroAM7_RS09535	COG0251	oxidation-reduction process
VroAM7_RS09560	COG0291	Belongs to the bacterial ribosomal protein bL35 family
VroAM7_RS09585	COG2188	Transcriptional regulator
VroAM7_RS09595	COG0010	Belongs to the arginase family
VroAM7_RS09605	COG2986	histidine ammonia-lyase
VroAM7_RS09620	COG0277	FAD linked oxidase domain protein
VroAM7_RS09620	COG0247	lactate metabolic process
VroAM7_RS09670	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
VroAM7_RS09675	COG1643	Atp-dependent helicase
VroAM7_RS09685	COG2949	membrane
VroAM7_RS09690	COG0471	metal ion transport
VroAM7_RS09715	COG0492	ferredoxin-NADP+ reductase activity
VroAM7_RS09720	COG4988	ABC transporter
VroAM7_RS09725	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
VroAM7_RS09735	COG2610	gluconate transmembrane transporter activity
VroAM7_RS09740	COG0583	DNA-binding transcription factor activity
VroAM7_RS09755	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
VroAM7_RS09765	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VroAM7_RS09765	COG4191	Histidine kinase
VroAM7_RS09780	COG3070	regulator of competence-specific genes
VroAM7_RS09790	COG2431	L-lysine efflux transmembrane transporter activity
VroAM7_RS09800	COG0076	glutamate decarboxylase activity
VroAM7_RS09810	COG1737	Transcriptional regulator
VroAM7_RS09820	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
VroAM7_RS09830	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
VroAM7_RS09865	COG0534	Mate efflux family protein
VroAM7_RS09870	COG0702	epimerase
VroAM7_RS09875	COG4667	esterase of the alpha-beta hydrolase superfamily
VroAM7_RS09885	COG2814	Major facilitator Superfamily
VroAM7_RS09890	COG1187	pseudouridine synthase activity
VroAM7_RS09895	COG1061	Type III restriction enzyme res subunit
VroAM7_RS09920	COG1216	Glycosyl transferase, family 2
VroAM7_RS09920	COG0463	Glycosyl transferase, family 2
VroAM7_RS09950	COG3313	Fe-S protein
VroAM7_RS09960	COG0659	secondary active sulfate transmembrane transporter activity
VroAM7_RS09990	COG0493	'glutamate synthase
VroAM7_RS10000	COG0398	Pfam SNARE associated Golgi protein
VroAM7_RS10005	COG4134	Bacterial extracellular solute-binding protein
VroAM7_RS10010	COG4135	transport system, permease component
VroAM7_RS10015	COG4136	ATPase activity
VroAM7_RS10020	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
VroAM7_RS10035	COG3604	Transcriptional regulator
VroAM7_RS10040	COG1151	hydroxylamine reductase activity
VroAM7_RS10045	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
VroAM7_RS10055	COG0564	pseudouridine synthase activity
VroAM7_RS10065	COG0733	neurotransmitter:sodium symporter activity
VroAM7_RS10075	COG0626	cystathionine gamma-synthase activity
VroAM7_RS10085	COG2818	Glycosylase
VroAM7_RS10115	COG1842	Phage shock protein A
VroAM7_RS10120	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
VroAM7_RS10130	COG4168	peptide transport system, permease
VroAM7_RS10135	COG4171	peptide transport system, permease
VroAM7_RS10145	COG4172	Belongs to the ABC transporter superfamily
VroAM7_RS10155	COG1227	inorganic diphosphatase activity
VroAM7_RS10170	COG0243	molybdopterin cofactor binding
VroAM7_RS10175	COG3005	denitrification pathway
VroAM7_RS10180	COG4459	periplasmic nitrate reductase
VroAM7_RS10185	COG0390	transport system, permease component
VroAM7_RS10190	COG2116	formate transmembrane transporter activity
VroAM7_RS10215	COG1434	Gram-negative-bacterium-type cell wall biogenesis
VroAM7_RS10220	COG1435	thymidine kinase activity
VroAM7_RS10225	COG0215	cysteine-tRNA ligase activity
VroAM7_RS10230	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
VroAM7_RS10235	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
VroAM7_RS10240	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
VroAM7_RS10245	COG3012	SEC-C Motif Domain Protein
VroAM7_RS10250	COG0140	phosphoribosyl-ATP diphosphatase activity
VroAM7_RS10250	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
VroAM7_RS10260	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
VroAM7_RS10265	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
VroAM7_RS10270	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
VroAM7_RS10270	COG0131	Imidazoleglycerol-phosphate dehydratase
VroAM7_RS10280	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
VroAM7_RS10295	COG1757	Na H antiporter
VroAM7_RS10305	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VroAM7_RS10315	COG0482	sulfurtransferase activity
VroAM7_RS10325	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
VroAM7_RS10335	COG2268	Band 7 protein
VroAM7_RS10345	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
VroAM7_RS10360	COG0300	oxidoreductase activity
VroAM7_RS10385	COG2226	methyltransferase
VroAM7_RS10400	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
VroAM7_RS10405	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
VroAM7_RS10425	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
VroAM7_RS10435	COG1674	ftsk spoiiie
VroAM7_RS10445	COG0686	Belongs to the AlaDH PNT family
VroAM7_RS10455	COG0583	DNA-binding transcription factor activity
VroAM7_RS10470	COG4166	transmembrane transport
VroAM7_RS10480	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
VroAM7_RS10485	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
VroAM7_RS10495	COG0539	negative regulation of cytoplasmic translation
VroAM7_RS10505	COG0616	signal peptide processing
VroAM7_RS10510	COG1028	Short-chain dehydrogenase reductase Sdr
VroAM7_RS10530	COG0835	chemotaxis
VroAM7_RS10530	COG0784	Response regulator, receiver
VroAM7_RS10535	COG1940	carbohydrate kinase activity
VroAM7_RS10540	COG0469	pyruvate kinase activity
VroAM7_RS10545	COG4667	esterase of the alpha-beta hydrolase superfamily
VroAM7_RS10560	COG0733	neurotransmitter:sodium symporter activity
VroAM7_RS10575	COG1263	PTS System
VroAM7_RS10575	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VroAM7_RS10580	COG0084	hydrolase, TatD family'
VroAM7_RS10595	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
VroAM7_RS10625	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
VroAM7_RS10640	COG1399	metal-binding, possibly nucleic acid-binding protein
VroAM7_RS10645	COG0424	maF-like protein
VroAM7_RS10650	COG0564	pseudouridine synthase activity
VroAM7_RS10655	COG1530	ribonuclease E activity
VroAM7_RS10660	COG0659	secondary active sulfate transmembrane transporter activity
VroAM7_RS10665	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
VroAM7_RS10670	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
VroAM7_RS10685	COG0489	protein tyrosine kinase activity
VroAM7_RS10700	COG2186	Transcriptional regulator
VroAM7_RS10705	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
VroAM7_RS10710	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
VroAM7_RS10720	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
VroAM7_RS10725	COG3706	GGDEF domain
VroAM7_RS10730	COG0366	Alpha amylase catalytic
VroAM7_RS10735	COG1122	ATPase activity
VroAM7_RS10740	COG4120	Belongs to the binding-protein-dependent transport system permease family
VroAM7_RS10765	COG0857	belongs to the CobB CobQ family
VroAM7_RS10765	COG0280	phosphate acetyltransferase
VroAM7_RS10770	COG3174	membrane
VroAM7_RS10775	COG0435	Glutathione S-transferase
VroAM7_RS10785	COG0444	Belongs to the ABC transporter superfamily
VroAM7_RS10790	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VroAM7_RS10795	COG0601	transmembrane transport
VroAM7_RS10805	COG0314	molybdopterin synthase activity
VroAM7_RS10810	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
VroAM7_RS10820	COG0521	Mo-molybdopterin cofactor biosynthetic process
VroAM7_RS10825	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
VroAM7_RS10830	COG0391	Required for morphogenesis under gluconeogenic growth conditions
VroAM7_RS10835	COG2198	Histidine kinase
VroAM7_RS10840	COG2204	response regulator
VroAM7_RS10845	COG0556	nucleotide-excision repair
VroAM7_RS10855	COG4657	Part of a membrane complex involved in electron transport
VroAM7_RS10865	COG4656	Part of a membrane complex involved in electron transport
VroAM7_RS10870	COG4658	electron transport chain
VroAM7_RS10875	COG4659	FMN binding
VroAM7_RS10880	COG4660	Part of a membrane complex involved in electron transport
VroAM7_RS10885	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
VroAM7_RS10890	COG0346	lactoylglutathione lyase activity
VroAM7_RS10900	COG2885	chlorophyll binding
VroAM7_RS10910	COG2056	Na+-H+ antiporter family
VroAM7_RS10920	COG5002	protein histidine kinase activity
VroAM7_RS10920	COG2205	protein histidine kinase activity
VroAM7_RS10920	COG0784	Response regulator, receiver
VroAM7_RS10925	COG3385	transposase activity
VroAM7_RS10935	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
VroAM7_RS10955	COG1454	alcohol dehydrogenase
VroAM7_RS10955	COG1012	belongs to the aldehyde dehydrogenase family
VroAM7_RS10960	COG2095	MarC family integral membrane protein
VroAM7_RS10965	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
VroAM7_RS10970	COG2165	general secretion pathway protein
VroAM7_RS10975	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
VroAM7_RS10980	COG1757	Na H antiporter
VroAM7_RS11005	COG3083	sulfuric ester hydrolase activity
VroAM7_RS11015	COG2214	Heat shock protein DnaJ domain protein
VroAM7_RS11025	COG0443	Heat shock 70 kDa protein
VroAM7_RS11030	COG0123	including yeast histone deacetylase and acetoin utilization protein
VroAM7_RS11045	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
VroAM7_RS11050	COG0778	Nitroreductase
VroAM7_RS11055	COG1902	pentaerythritol trinitrate reductase activity
VroAM7_RS11055	COG0446	pyridine nucleotide-disulphide oxidoreductase
VroAM7_RS11060	COG0616	signal peptide processing
VroAM7_RS11065	COG0252	asparaginase activity
VroAM7_RS11070	COG3139	Protein of unknown function (DUF1315)
VroAM7_RS11080	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VroAM7_RS11085	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
VroAM7_RS11110	COG2226	methyltransferase
VroAM7_RS11130	COG1785	Belongs to the alkaline phosphatase family
VroAM7_RS11150	COG0668	transmembrane transport
VroAM7_RS11155	COG2261	transglycosylase associated protein
VroAM7_RS11160	COG2983	Belongs to the UPF0260 family
VroAM7_RS11170	COG2964	Protein conserved in bacteria
VroAM7_RS11180	COG0251	oxidation-reduction process
VroAM7_RS11185	COG0814	amino acid
VroAM7_RS11190	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
VroAM7_RS11195	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
VroAM7_RS11205	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
VroAM7_RS11215	COG2832	Protein of unknown function (DUF454)
VroAM7_RS11225	COG0745	RESPONSE REGULATOR receiver
VroAM7_RS11230	COG0583	DNA-binding transcription factor activity
VroAM7_RS11240	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
VroAM7_RS11245	COG1286	toxin biosynthetic process
VroAM7_RS11250	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
VroAM7_RS11255	COG0285	dihydrofolate synthase activity
VroAM7_RS11280	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
VroAM7_RS11285	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
VroAM7_RS11290	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
VroAM7_RS11310	COG3101	peptidyl-lysine hydroxylation
VroAM7_RS11315	COG2860	membrane
VroAM7_RS11320	COG1028	Short-chain dehydrogenase reductase Sdr
VroAM7_RS11325	COG0583	DNA-binding transcription factor activity
VroAM7_RS11335	COG2890	protein-(glutamine-N5) methyltransferase activity
VroAM7_RS11340	COG2840	Smr protein MutS2
VroAM7_RS11345	COG2062	phosphohistidine phosphatase, SixA
VroAM7_RS11365	COG0183	Belongs to the thiolase family
VroAM7_RS11380	COG2067	long-chain fatty acid transport protein
VroAM7_RS11390	COG2853	Lipoprotein
VroAM7_RS11405	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
VroAM7_RS11410	COG1138	Cytochrome C-type biogenesis protein
VroAM7_RS11425	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
VroAM7_RS11430	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
VroAM7_RS11435	COG4133	protoheme IX ABC transporter activity
VroAM7_RS11445	COG0835	chemotaxis
VroAM7_RS11455	COG1192	Involved in chromosome partitioning
VroAM7_RS11460	COG2201	protein-glutamate methylesterase activity
VroAM7_RS11465	COG0643	Histidine kinase
VroAM7_RS11465	COG0784	Response regulator, receiver
VroAM7_RS11465	COG2198	Histidine kinase
VroAM7_RS11470	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
VroAM7_RS11505	COG1684	flagellar biosynthetic protein fliR
VroAM7_RS11510	COG1987	bacterial-type flagellum assembly
VroAM7_RS11535	COG1580	Controls the rotational direction of flagella during chemotaxis
VroAM7_RS11560	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
VroAM7_RS11570	COG1677	Flagellar hook-basal body complex protein FliE
VroAM7_RS11590	COG1516	flagellar protein fliS
VroAM7_RS11600	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
VroAM7_RS11605	COG1334	flagellar protein FlaG
VroAM7_RS11610	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VroAM7_RS11615	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VroAM7_RS11625	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VroAM7_RS11630	COG2211	Major facilitator Superfamily
VroAM7_RS11635	COG1486	melibiose metabolic process
VroAM7_RS11640	COG2169	Transcriptional regulator
VroAM7_RS11645	COG2837	iron assimilation
VroAM7_RS11670	COG1393	Belongs to the ArsC family
VroAM7_RS11690	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
VroAM7_RS11695	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
VroAM7_RS11700	COG2716	regulation of RNA biosynthetic process
VroAM7_RS11730	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
VroAM7_RS11770	COG0583	DNA-binding transcription factor activity
VroAM7_RS11775	COG0697	spore germination
VroAM7_RS11790	COG3706	GGDEF domain
VroAM7_RS11810	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
VroAM7_RS11825	COG4783	chaperone-mediated protein folding
VroAM7_RS11830	COG1393	Belongs to the ArsC family
VroAM7_RS11850	COG2233	PERMEase
VroAM7_RS11855	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
VroAM7_RS11860	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
VroAM7_RS11865	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
VroAM7_RS11870	COG0121	glutamine amidotransferase
VroAM7_RS11875	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
VroAM7_RS11880	COG1960	acyl-CoA dehydrogenase activity
VroAM7_RS11895	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
VroAM7_RS11905	COG2226	methyltransferase
VroAM7_RS11910	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
VroAM7_RS11915	COG1388	LysM domain
VroAM7_RS11915	COG0741	lytic transglycosylase activity
VroAM7_RS11930	COG0347	Belongs to the P(II) protein family
VroAM7_RS11950	COG0587	DNA-directed DNA polymerase activity
VroAM7_RS11965	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
VroAM7_RS11975	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
VroAM7_RS11980	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
VroAM7_RS11990	COG0750	zinc metalloprotease
VroAM7_RS12000	COG0575	Belongs to the CDS family
VroAM7_RS12005	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
VroAM7_RS12030	COG0024	Methionine aminopeptidase
VroAM7_RS12045	COG0564	pseudouridine synthase activity
VroAM7_RS12050	COG3098	single-species biofilm formation
VroAM7_RS12085	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
VroAM7_RS12100	COG1720	tRNA m6t6A37 methyltransferase activity
VroAM7_RS12125	COG0733	neurotransmitter:sodium symporter activity
VroAM7_RS12135	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
VroAM7_RS12140	COG0514	ATP-dependent DNA helicase (RecQ)
VroAM7_RS12145	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
VroAM7_RS12160	COG1477	protein flavinylation
VroAM7_RS12170	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
VroAM7_RS12195	COG0271	Belongs to the BolA IbaG family
VroAM7_RS12225	COG1595	DNA-templated transcription, initiation
VroAM7_RS12245	COG3248	Nucleoside-binding outer membrane protein
VroAM7_RS12250	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
VroAM7_RS12255	COG0693	protein deglycase activity
VroAM7_RS12260	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
VroAM7_RS12265	COG2166	iron-sulfur cluster assembly
VroAM7_RS12270	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
VroAM7_RS12275	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
VroAM7_RS12285	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
VroAM7_RS12285	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
VroAM7_RS12295	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
VroAM7_RS12300	COG1074	ATP-dependent DNA helicase activity
VroAM7_RS12305	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
VroAM7_RS12325	COG3141	response to X-ray
VroAM7_RS12355	COG2171	N-acyltransferase activity
VroAM7_RS12360	COG0584	glycerophosphoryl diester phosphodiesterase
VroAM7_RS12365	COG2271	Major facilitator Superfamily
VroAM7_RS12375	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
VroAM7_RS12385	COG1349	DNA-binding transcription factor activity
VroAM7_RS12390	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
VroAM7_RS12415	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
VroAM7_RS12420	COG1609	Transcriptional regulator
VroAM7_RS12430	COG2017	converts alpha-aldose to the beta-anomer
VroAM7_RS12440	COG1085	galactose-1-phosphate uridylyltransferase
VroAM7_RS12445	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
VroAM7_RS12450	COG0768	penicillin binding
VroAM7_RS12455	COG1609	Transcriptional regulator
VroAM7_RS12460	COG3250	beta-galactosidase activity
VroAM7_RS12465	COG2731	YhcH YjgK YiaL family protein
VroAM7_RS12470	COG0531	amino acid
VroAM7_RS12475	COG0583	DNA-binding transcription factor activity
VroAM7_RS12480	COG2059	Chromate
VroAM7_RS12535	COG4964	Belongs to the GSP D family
VroAM7_RS12560	COG1022	Amp-dependent synthetase and ligase
VroAM7_RS12570	COG0583	DNA-binding transcription factor activity
VroAM7_RS12575	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
VroAM7_RS12580	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
VroAM7_RS12590	COG0560	Phosphoserine phosphatase
VroAM7_RS12600	COG0813	purine-nucleoside phosphorylase activity
VroAM7_RS12610	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
VroAM7_RS12615	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
VroAM7_RS12620	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
VroAM7_RS12625	COG0084	hydrolase, TatD family'
VroAM7_RS12725	COG2003	Belongs to the UPF0758 family
VroAM7_RS12750	COG0714	Associated with various cellular activities
VroAM7_RS12765	COG0629	single-stranded DNA binding
VroAM7_RS12800	COG0681	Belongs to the peptidase S26 family
VroAM7_RS12815	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
VroAM7_RS12935	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
VroAM7_RS12955	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
VroAM7_RS12990	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
VroAM7_RS12995	COG3706	GGDEF domain
VroAM7_RS13015	COG3153	acetyltransferase
VroAM7_RS13020	COG3154	lipid carrier protein
VroAM7_RS13030	COG0826	peptidase U32
VroAM7_RS13035	COG0826	peptidase U32
VroAM7_RS13045	COG0534	Mate efflux family protein
VroAM7_RS13065	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
VroAM7_RS13085	COG0195	Participates in both transcription termination and antitermination
VroAM7_RS13105	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
VroAM7_RS13120	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
VroAM7_RS13125	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
VroAM7_RS13135	COG1534	Rna-binding protein
VroAM7_RS13140	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
VroAM7_RS13145	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
VroAM7_RS13150	COG2027	D-alanyl-D-alanine carboxypeptidase
VroAM7_RS13160	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
VroAM7_RS13165	COG0739	heme binding
VroAM7_RS13170	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
VroAM7_RS13180	COG0316	Belongs to the HesB IscA family
VroAM7_RS13190	COG0628	permease
VroAM7_RS13200	COG2205	protein histidine kinase activity
VroAM7_RS13200	COG0784	Response regulator, receiver
VroAM7_RS13205	COG0747	negative chemotaxis
VroAM7_RS13215	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VroAM7_RS13220	COG0444	Belongs to the ABC transporter superfamily
VroAM7_RS13225	COG4608	Belongs to the ABC transporter superfamily
VroAM7_RS13235	COG2971	BadF BadG BcrA BcrD
VroAM7_RS13250	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
VroAM7_RS13255	COG3842	ATPase activity
VroAM7_RS13265	COG1840	ABC-type Fe3 transport system, periplasmic component
VroAM7_RS13270	COG0004	ammonium transporteR
VroAM7_RS13285	COG1049	propionate catabolic process, 2-methylcitrate cycle
VroAM7_RS13290	COG1752	Esterase of the alpha-beta hydrolase superfamily
VroAM7_RS13295	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
VroAM7_RS13300	COG1643	Atp-dependent helicase
VroAM7_RS13315	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
VroAM7_RS13330	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
VroAM7_RS13345	COG1560	Kdo2-lipid A biosynthetic process
VroAM7_RS13350	COG0842	Transport permease protein
VroAM7_RS13355	COG1131	(ABC) transporter
VroAM7_RS13360	COG0659	secondary active sulfate transmembrane transporter activity
VroAM7_RS13365	COG0288	reversible hydration of carbon dioxide
VroAM7_RS13380	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
VroAM7_RS13385	COG0508	dehydrogenase complex catalyzes the overall conversion of
VroAM7_RS13390	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
VroAM7_RS13395	COG2186	Transcriptional regulator
VroAM7_RS13415	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
VroAM7_RS13420	COG1459	type II secretion system
VroAM7_RS13430	COG0237	dephospho-CoA kinase activity
VroAM7_RS13435	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
VroAM7_RS13440	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
VroAM7_RS13465	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
VroAM7_RS13470	COG4137	Cytochrome C assembly protein
VroAM7_RS13475	COG4536	flavin adenine dinucleotide binding
VroAM7_RS13495	COG0612	Peptidase, M16
VroAM7_RS13500	COG1238	metal cluster binding
VroAM7_RS13510	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
VroAM7_RS13515	COG5016	pyruvate
VroAM7_RS13515	COG0511	ligase activity, forming carbon-carbon bonds
VroAM7_RS13520	COG3630	sodium ion export across plasma membrane
VroAM7_RS13580	COG0527	aspartate kinase activity
VroAM7_RS13595	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
VroAM7_RS13600	COG1546	Belongs to the CinA family
VroAM7_RS13610	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
VroAM7_RS13640	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
VroAM7_RS13650	COG0148	phosphopyruvate hydratase activity
VroAM7_RS13660	COG3956	TIGRFAM MazG family protein
VroAM7_RS13665	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
VroAM7_RS13690	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
VroAM7_RS13695	COG1381	Involved in DNA repair and RecF pathway recombination
VroAM7_RS13700	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
VroAM7_RS13720	COG3086	response to oxidative stress
VroAM7_RS13735	COG1595	DNA-templated transcription, initiation
VroAM7_RS13740	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
VroAM7_RS13750	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
VroAM7_RS13775	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VroAM7_RS13780	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VroAM7_RS13785	COG3079	Belongs to the UPF0149 family
VroAM7_RS13790	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
VroAM7_RS13800	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
VroAM7_RS13810	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
VroAM7_RS13820	COG0583	DNA-binding transcription factor activity
VroAM7_RS13835	COG0668	transmembrane transport
VroAM7_RS13840	COG0191	fructose-bisphosphate aldolase activity
VroAM7_RS13860	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
VroAM7_RS13865	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
VroAM7_RS13880	COG2356	endonuclease I
VroAM7_RS13885	COG1385	rRNA (uridine-N3-)-methyltransferase activity
VroAM7_RS13890	COG0189	ligase activity
VroAM7_RS13895	COG1678	Uncharacterized ACR, COG1678
VroAM7_RS13900	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
VroAM7_RS13915	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
VroAM7_RS13920	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
VroAM7_RS13925	COG0762	integral membrane protein
VroAM7_RS13940	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
VroAM7_RS13945	COG0635	Involved in the biosynthesis of porphyrin-containing compound
VroAM7_RS14045	COG1012	belongs to the aldehyde dehydrogenase family
VroAM7_RS14095	COG1609	Transcriptional regulator
VroAM7_RS14105	COG1486	melibiose metabolic process
VroAM7_RS14110	COG1447	Phosphotransferase system cellobiose-specific component IIA
VroAM7_RS14120	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
VroAM7_RS14130	COG1028	Short-chain dehydrogenase reductase Sdr
VroAM7_RS14140	COG0795	lipopolysaccharide-transporting ATPase activity
VroAM7_RS14145	COG0795	lipopolysaccharide-transporting ATPase activity
VroAM7_RS14155	COG2927	DNA polymerase III (CHI subunit)
VroAM7_RS14160	COG0525	valine-tRNA ligase activity
VroAM7_RS14170	COG0456	acetyltransferase
VroAM7_RS14210	COG0251	oxidation-reduction process
VroAM7_RS14215	COG0204	Acyl-transferase
VroAM7_RS14225	COG5007	Belongs to the BolA IbaG family
VroAM7_RS14235	COG2854	intermembrane phospholipid transfer
VroAM7_RS14240	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
VroAM7_RS14245	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
VroAM7_RS14250	COG1127	ABC transporter
VroAM7_RS14260	COG0517	IMP dehydrogenase activity
VroAM7_RS14260	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
VroAM7_RS14270	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
VroAM7_RS14275	COG1137	ATPase activity
VroAM7_RS14285	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
VroAM7_RS14290	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
VroAM7_RS14300	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
VroAM7_RS14305	COG2239	Acts as a magnesium transporter
VroAM7_RS14310	COG0312	modulator of DNA gyrase
VroAM7_RS14320	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
VroAM7_RS14325	COG0564	pseudouridine synthase activity
VroAM7_RS14340	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
VroAM7_RS14345	COG0312	modulator of DNA gyrase
VroAM7_RS14350	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
VroAM7_RS14355	COG3164	Protein of unknown function
VroAM7_RS14365	COG0424	maF-like protein
VroAM7_RS14370	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
VroAM7_RS14375	COG1792	Involved in formation and maintenance of cell shape
VroAM7_RS14380	COG1077	Cell shape determining protein MreB Mrl
VroAM7_RS14415	COG2165	general secretion pathway protein
VroAM7_RS14425	COG1459	type II secretion system
VroAM7_RS14430	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
VroAM7_RS14440	COG3409	Peptidoglycan-binding domain 1 protein
VroAM7_RS14440	COG3267	Type II secretory pathway component ExeA
VroAM7_RS14465	COG2200	EAL domain
VroAM7_RS14465	COG2199	diguanylate cyclase activity
VroAM7_RS14470	COG0629	single-stranded DNA binding
VroAM7_RS14485	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
VroAM7_RS14495	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
VroAM7_RS14505	COG0527	aspartate kinase activity
VroAM7_RS14510	COG1410	methionine synthase
VroAM7_RS14510	COG0646	methionine synthase
VroAM7_RS14595	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
VroAM7_RS14615	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
VroAM7_RS14620	COG0735	belongs to the Fur family
VroAM7_RS14635	COG0432	Pfam Uncharacterised protein family UPF0047
VroAM7_RS14645	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
VroAM7_RS14650	COG0305	Participates in initiation and elongation during chromosome replication
VroAM7_RS14680	COG2965	DNA replication, synthesis of RNA primer
VroAM7_RS14690	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
VroAM7_RS14695	COG0338	D12 class N6 adenine-specific DNA methyltransferase
VroAM7_RS14740	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
VroAM7_RS14750	COG0678	peroxiredoxin activity
VroAM7_RS14750	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
VroAM7_RS14765	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
VroAM7_RS14765	COG0165	Argininosuccinate lyase
VroAM7_RS14780	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
VroAM7_RS14790	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
VroAM7_RS14800	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
VroAM7_RS14805	COG0527	aspartate kinase activity
VroAM7_RS14805	COG0460	homoserine dehydrogenase
VroAM7_RS14810	COG0626	cystathionine gamma-synthase activity
VroAM7_RS14820	COG0281	malic enzyme
VroAM7_RS14830	COG2906	2 iron, 2 sulfur cluster binding
VroAM7_RS14840	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
VroAM7_RS14855	COG2168	tRNA wobble position uridine thiolation
VroAM7_RS14860	COG2923	Belongs to the DsrF TusC family
VroAM7_RS14865	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
VroAM7_RS14870	COG2964	Protein conserved in bacteria
VroAM7_RS14875	COG0545	Peptidyl-prolyl cis-trans isomerase
VroAM7_RS14890	COG1446	asparaginase
VroAM7_RS14900	COG1047	Peptidyl-prolyl cis-trans
VroAM7_RS14915	COG2249	NAD(P)H dehydrogenase (quinone) activity
VroAM7_RS14925	COG0488	(ABC) transporter
VroAM7_RS14935	COG0429	hydrolase of the alpha beta-hydrolase fold
VroAM7_RS14940	COG3089	Belongs to the UPF0270 family
VroAM7_RS14945	COG3954	Phosphoribulokinase
VroAM7_RS14950	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
VroAM7_RS14970	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
VroAM7_RS14975	COG0512	Glutamine amidotransferase of anthranilate synthase
VroAM7_RS14990	COG0546	phosphoglycolate phosphatase activity
VroAM7_RS14995	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
VroAM7_RS15000	COG0557	exoribonuclease II activity
VroAM7_RS15010	COG1017	nitric oxide dioxygenase activity
VroAM7_RS15010	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
VroAM7_RS15015	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
VroAM7_RS15025	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
VroAM7_RS15030	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
VroAM7_RS15035	COG0330	HflC and HflK could
VroAM7_RS15040	COG0330	HflC and HflK could
VroAM7_RS15045	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
VroAM7_RS15060	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
VroAM7_RS15065	COG0860	N-Acetylmuramoyl-L-alanine amidase
VroAM7_RS15070	COG0802	atpase or kinase
VroAM7_RS15075	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
VroAM7_RS15150	COG1162	GTPase activity
VroAM7_RS15160	COG0471	metal ion transport
VroAM7_RS15175	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
VroAM7_RS15180	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
VroAM7_RS15195	COG1045	serine acetyltransferase
VroAM7_RS15200	COG4942	peptidase
VroAM7_RS15220	COG1053	succinate dehydrogenase
VroAM7_RS15225	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
VroAM7_RS15255	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
VroAM7_RS15260	COG1509	lysine 2,3-aminomutase activity
VroAM7_RS15265	COG1285	pathogenesis
VroAM7_RS15285	COG0534	Mate efflux family protein
VroAM7_RS15295	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
VroAM7_RS15300	COG3678	ATP-independent chaperone mediated protein folding
VroAM7_RS15305	COG0745	RESPONSE REGULATOR receiver
VroAM7_RS15310	COG2205	protein histidine kinase activity
VroAM7_RS15320	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
VroAM7_RS15325	COG3030	protein affecting phage T7 exclusion by the F plasmid
VroAM7_RS15330	COG1027	Aspartate ammonia-lyase
VroAM7_RS15335	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
VroAM7_RS15340	COG4232	protein-disulfide reductase activity
VroAM7_RS15350	COG2095	MarC family integral membrane protein
VroAM7_RS15360	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
VroAM7_RS15380	COG0784	Response regulator, receiver
VroAM7_RS15380	COG2198	Histidine kinase
VroAM7_RS15380	COG2205	protein histidine kinase activity
VroAM7_RS15385	COG2814	Major facilitator Superfamily
VroAM7_RS15400	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
VroAM7_RS15405	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
VroAM7_RS15410	COG0511	ligase activity, forming carbon-carbon bonds
VroAM7_RS15415	COG0439	Biotin carboxylase
VroAM7_RS15430	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
VroAM7_RS15435	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
VroAM7_RS15440	COG5001	Diguanylate cyclase
VroAM7_RS15440	COG3300	MHYT domain
VroAM7_RS15480	COG1982	Orn Lys Arg decarboxylase major
VroAM7_RS15485	COG0531	amino acid
VroAM7_RS15500	COG3710	Transcriptional regulator
VroAM7_RS15505	COG0789	Transcriptional regulator
VroAM7_RS15510	COG0138	bifunctional purine biosynthesis protein purh
VroAM7_RS15515	COG0151	Belongs to the GarS family
VroAM7_RS15530	COG1253	flavin adenine dinucleotide binding
VroAM7_RS15535	COG3068	Protein conserved in bacteria
VroAM7_RS15545	COG1573	uracil-dna glycosylase
VroAM7_RS15555	COG2816	NAD+ diphosphatase activity
VroAM7_RS15560	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
VroAM7_RS15580	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
VroAM7_RS15595	COG0250	Participates in transcription elongation, termination and antitermination
VroAM7_RS15600	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
VroAM7_RS15645	COG0812	UDP-N-acetylmuramate dehydrogenase activity
VroAM7_RS15655	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
VroAM7_RS15770	COG1309	transcriptional regulator
VroAM7_RS15775	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
VroAM7_RS15780	COG0534	Mate efflux family protein
VroAM7_RS15800	COG2937	Belongs to the GPAT DAPAT family
VroAM7_RS15810	COG3161	chorismate lyase activity
VroAM7_RS15815	COG1580	Controls the rotational direction of flagella during chemotaxis
VroAM7_RS15820	COG0705	Rhomboid family
VroAM7_RS15825	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
VroAM7_RS15840	COG2177	Part of the ABC transporter FtsEX involved in
VroAM7_RS15845	COG2884	Cell division ATP-binding protein ftsE
VroAM7_RS15850	COG0552	protein localization to endoplasmic reticulum
VroAM7_RS15850	COG0552	protein localization to endoplasmic reticulum
VroAM7_RS15855	COG0742	ribosomal rna small subunit methyltransferase
VroAM7_RS15865	COG2095	MarC family integral membrane protein
VroAM7_RS15915	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
VroAM7_RS15920	COG0640	Transcriptional regulator
VroAM7_RS15925	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
VroAM7_RS15930	COG1280	lysine exporter protein (LysE YggA)
VroAM7_RS15935	COG2267	carboxylic ester hydrolase activity
VroAM7_RS15940	COG0561	phosphatase activity
VroAM7_RS15955	COG3148	PFAM DTW domain containing protein
VroAM7_RS15960	COG2200	EAL domain
VroAM7_RS15960	COG2199	diguanylate cyclase activity
VroAM7_RS15960	COG3287	FIST C domain
VroAM7_RS15965	COG1011	Hydrolase
VroAM7_RS15985	COG0019	diaminopimelate decarboxylase activity
VroAM7_RS16000	COG3072	Adenylate cyclase
VroAM7_RS16010	COG1587	Uroporphyrinogen-III synthase
VroAM7_RS16015	COG2959	enzyme of heme biosynthesis
VroAM7_RS16020	COG3071	HemY protein
VroAM7_RS16075	COG0633	Ferredoxin
VroAM7_RS16080	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
VroAM7_RS16095	COG3118	belongs to the thioredoxin family
VroAM7_RS16110	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
VroAM7_RS16125	COG0514	ATP-dependent DNA helicase (RecQ)
VroAM7_RS16130	COG2962	Rard protein
VroAM7_RS16150	COG1280	lysine exporter protein (LysE YggA)
VroAM7_RS16155	COG0405	Gamma-glutamyltransferase
VroAM7_RS16165	COG0210	DNA helicase
VroAM7_RS16175	COG3220	belongs to the UPF0276 family
VroAM7_RS16195	COG2814	Major facilitator Superfamily
VroAM7_RS16205	COG0006	proline dipeptidase activity
VroAM7_RS16205	COG0006	proline dipeptidase activity
VroAM7_RS16220	COG2104	thiamine diphosphate biosynthetic process
VroAM7_RS16225	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
VroAM7_RS16245	COG2132	Multicopper oxidase
VroAM7_RS16295	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
VroAM7_RS16320	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
VroAM7_RS16325	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
VroAM7_RS16330	COG0551	DNA topoisomerase type I activity
VroAM7_RS16340	COG0758	DNA mediated transformation
VroAM7_RS16350	COG0242	peptide deformylase activity
VroAM7_RS16360	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
VroAM7_RS16360	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
VroAM7_RS16365	COG0569	domain protein
VroAM7_RS16370	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
VroAM7_RS16380	COG1272	protein, Hemolysin III
VroAM7_RS16385	COG4326	sporulation control protein
VroAM7_RS16395	COG3084	Protein conserved in bacteria
VroAM7_RS16405	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
VroAM7_RS16410	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
VroAM7_RS16415	COG0204	Acyl-transferase
VroAM7_RS16505	COG3978	acetolactate synthase activity
VroAM7_RS16510	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
VroAM7_RS16515	COG0129	dihydroxy-acid dehydratase activity
VroAM7_RS16525	COG0583	DNA-binding transcription factor activity
VroAM7_RS16530	COG2814	Major facilitator Superfamily
VroAM7_RS16535	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VroAM7_RS16540	COG0765	amino acid transport
VroAM7_RS16550	COG0355	proton-transporting ATP synthase activity, rotational mechanism
VroAM7_RS16560	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
VroAM7_RS16590	COG3312	ion transport
VroAM7_RS16595	COG1475	DNA binding
VroAM7_RS16600	COG1192	Involved in chromosome partitioning
VroAM7_RS16615	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
VroAM7_RS16645	COG1126	abc transporter atp-binding protein
VroAM7_RS16715	COG1051	belongs to the nudix hydrolase family
VroAM7_RS16720	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
VroAM7_RS16725	COG5001	Diguanylate cyclase
VroAM7_RS16735	COG1129	ABC transporter
VroAM7_RS16740	COG1172	Belongs to the binding-protein-dependent transport system permease family
VroAM7_RS16745	COG1879	ABC-type sugar transport system periplasmic component
VroAM7_RS16750	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VroAM7_RS16755	COG1609	Transcriptional regulator
VroAM7_RS16760	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
VroAM7_RS16775	COG4607	ABC-type enterochelin transport system periplasmic component
VroAM7_RS16780	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VroAM7_RS16785	COG4605	iron ion homeostasis
VroAM7_RS16790	COG4604	ABC transporter, ATP-binding protein
VroAM7_RS16795	COG0789	Transcriptional regulator
VroAM7_RS16805	COG4206	TonB-dependent receptor
VroAM7_RS16820	COG2165	general secretion pathway protein
VroAM7_RS16830	COG2962	Rard protein
VroAM7_RS16845	COG0671	phosphoesterase, PA-phosphatase related
VroAM7_RS16895	COG2067	long-chain fatty acid transport protein
VroAM7_RS16900	COG1234	tRNA 3'-trailer cleavage
VroAM7_RS16915	COG5642	Protein of unknown function (DUF2384)
VroAM7_RS16925	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
VroAM7_RS16925	COG2755	lipolytic protein G-D-S-L family
VroAM7_RS16935	COG1902	pentaerythritol trinitrate reductase activity
VroAM7_RS16940	COG0346	lactoylglutathione lyase activity
VroAM7_RS16960	COG0739	heme binding
VroAM7_RS16975	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
VroAM7_RS16995	COG0628	permease
VroAM7_RS17015	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
VroAM7_RS17020	COG1999	signal sequence binding
VroAM7_RS17035	COG3005	denitrification pathway
VroAM7_RS17050	COG0583	DNA-binding transcription factor activity
VroAM7_RS17180	COG3594	Acyltransferase
VroAM7_RS17190	COG2816	NAD+ diphosphatase activity
VroAM7_RS17195	COG1132	(ABC) transporter
VroAM7_RS17205	COG0583	DNA-binding transcription factor activity
VroAM7_RS17210	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
VroAM7_RS17235	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
VroAM7_RS17240	COG0583	DNA-binding transcription factor activity
VroAM7_RS17260	COG0509	glycine decarboxylation via glycine cleavage system
VroAM7_RS17265	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
VroAM7_RS17275	COG0404	The glycine cleavage system catalyzes the degradation of glycine
VroAM7_RS17285	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VroAM7_RS17290	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VroAM7_RS17305	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
VroAM7_RS17305	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VroAM7_RS17305	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VroAM7_RS17310	COG1105	Belongs to the carbohydrate kinase PfkB family
VroAM7_RS17315	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
VroAM7_RS17315	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
VroAM7_RS17320	COG1609	Transcriptional regulator
VroAM7_RS17340	COG0765	amino acid transport
VroAM7_RS17345	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VroAM7_RS17350	COG0765	amino acid transport
VroAM7_RS17355	COG1126	abc transporter atp-binding protein
VroAM7_RS17365	COG1979	alcohol dehydrogenase
VroAM7_RS17370	COG2207	Transcriptional regulator
VroAM7_RS17380	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
VroAM7_RS17390	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VroAM7_RS17405	COG0784	Response regulator, receiver
VroAM7_RS17405	COG3437	response regulator, receiver
VroAM7_RS17410	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
VroAM7_RS17420	COG0840	transmembrane signaling receptor activity
VroAM7_RS17430	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
VroAM7_RS17435	COG0513	Belongs to the DEAD box helicase family
VroAM7_RS17440	COG4943	cyclic-guanylate-specific phosphodiesterase activity
VroAM7_RS17455	COG3038	cytochrome b561
VroAM7_RS17465	COG2116	formate transmembrane transporter activity
VroAM7_RS17475	COG0583	DNA-binding transcription factor activity
VroAM7_RS17485	COG3593	DNA synthesis involved in DNA repair
VroAM7_RS17490	COG0737	Belongs to the 5'-nucleotidase family
VroAM7_RS17505	COG0646	methionine synthase
VroAM7_RS17505	COG1410	methionine synthase
VroAM7_RS17520	COG2267	carboxylic ester hydrolase activity
VroAM7_RS17525	COG2067	long-chain fatty acid transport protein
VroAM7_RS17540	COG2050	protein possibly involved in aromatic compounds catabolism
VroAM7_RS17575	COG0484	heat shock protein binding
VroAM7_RS17585	COG3300	MHYT domain
VroAM7_RS17585	COG5001	Diguanylate cyclase
VroAM7_RS17590	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
VroAM7_RS17600	COG4181	ATPase activity
VroAM7_RS17605	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
VroAM7_RS17615	COG1984	allophanate hydrolase subunit 2
VroAM7_RS17620	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
VroAM7_RS17630	COG3447	MASE1 domain protein
VroAM7_RS17630	COG5002	protein histidine kinase activity
VroAM7_RS17630	COG5001	Diguanylate cyclase
VroAM7_RS17635	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
VroAM7_RS17650	COG0583	DNA-binding transcription factor activity
VroAM7_RS17655	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VroAM7_RS17655	COG0045	succinate-CoA ligase (ADP-forming) activity
VroAM7_RS17655	COG1042	CoA-binding domain protein
VroAM7_RS17660	COG3266	domain, Protein
VroAM7_RS17675	COG0023	Translation Initiation Factor
VroAM7_RS17705	COG3140	Belongs to the UPF0181 family
VroAM7_RS17720	COG0745	RESPONSE REGULATOR receiver
VroAM7_RS17730	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
VroAM7_RS17735	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
VroAM7_RS17775	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
VroAM7_RS17780	COG4149	molybdate abc transporter
VroAM7_RS17785	COG0725	ABC transporter, periplasmic molybdate-binding protein
VroAM7_RS17795	COG3111	PFAM Bacterial OB fold (BOF) protein
VroAM7_RS17805	COG4067	protein conserved in archaea
VroAM7_RS17805	COG0189	ligase activity
VroAM7_RS17820	COG0534	Mate efflux family protein
VroAM7_RS17830	COG0602	queuosine metabolic process
VroAM7_RS17835	COG1328	CTP reductase activity
VroAM7_RS17890	COG2199	diguanylate cyclase activity
VroAM7_RS17910	COG0840	transmembrane signaling receptor activity
VroAM7_RS17925	COG2199	diguanylate cyclase activity
VroAM7_RS17925	COG2203	Gaf domain
VroAM7_RS17935	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
VroAM7_RS17940	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
VroAM7_RS17995	COG1570	exodeoxyribonuclease VII activity
VroAM7_RS18020	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
VroAM7_RS18030	COG1403	HNH endonuclease
VroAM7_RS18065	COG0210	DNA helicase
VroAM7_RS18100	COG0446	pyridine nucleotide-disulphide oxidoreductase
VroAM7_RS18135	COG2197	response regulator
VroAM7_RS18140	COG3851	Histidine kinase
VroAM7_RS18145	COG2271	Major facilitator Superfamily
VroAM7_RS18150	COG1482	cell wall glycoprotein biosynthetic process
VroAM7_RS18160	COG0628	permease
VroAM7_RS18170	COG1566	PFAM secretion protein HlyD family protein
VroAM7_RS18200	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
VroAM7_RS18205	COG3118	belongs to the thioredoxin family
VroAM7_RS18220	COG2205	protein histidine kinase activity
VroAM7_RS18220	COG0784	Response regulator, receiver
VroAM7_RS18230	COG2200	EAL domain
VroAM7_RS18230	COG2202	Pas domain
VroAM7_RS18230	COG2199	diguanylate cyclase activity
VroAM7_RS18265	COG0840	transmembrane signaling receptor activity
VroAM7_RS18270	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
VroAM7_RS18290	COG2116	formate transmembrane transporter activity
VroAM7_RS18300	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
VroAM7_RS18350	COG0840	transmembrane signaling receptor activity
VroAM7_RS18380	COG0277	FAD linked oxidase domain protein
VroAM7_RS18385	COG0583	DNA-binding transcription factor activity
VroAM7_RS18400	COG2425	protein containing a von Willebrand factor type A (vWA) domain
VroAM7_RS18415	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
VroAM7_RS18425	COG1288	antiporter activity
VroAM7_RS18435	COG2814	Major facilitator Superfamily
VroAM7_RS18445	COG3040	lipid binding
VroAM7_RS18480	COG0419	ATPase involved in DNA repair
VroAM7_RS18485	COG0420	3'-5' exonuclease activity
VroAM7_RS18555	COG0631	protein serine/threonine phosphatase activity
VroAM7_RS18590	COG0515	serine threonine protein kinase
VroAM7_RS18590	COG2815	serine threonine protein kinase
VroAM7_RS18610	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
VroAM7_RS18615	COG2801	Transposase and inactivated derivatives
VroAM7_RS18650	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
VroAM7_RS18650	COG2146	nitrite reductase [NAD(P)H] activity
VroAM7_RS18655	COG1116	anion transmembrane transporter activity
VroAM7_RS18660	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
VroAM7_RS18665	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
VroAM7_RS18665	COG1116	anion transmembrane transporter activity
VroAM7_RS18675	COG3707	response regulator
VroAM7_RS18695	COG0243	molybdopterin cofactor binding
VroAM7_RS18705	COG5001	Diguanylate cyclase
VroAM7_RS18705	COG5002	protein histidine kinase activity
VroAM7_RS18710	COG0814	amino acid
VroAM7_RS18725	COG3706	GGDEF domain
VroAM7_RS18750	COG1785	Belongs to the alkaline phosphatase family
VroAM7_RS18760	COG0210	DNA helicase
VroAM7_RS18765	COG1289	transmembrane transporter activity
VroAM7_RS18785	COG0784	Response regulator, receiver
VroAM7_RS18785	COG0835	chemotaxis
VroAM7_RS18790	COG0778	Nitroreductase
VroAM7_RS18795	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
VroAM7_RS18820	COG3069	C4-dicarboxylate transmembrane transporter activity
VroAM7_RS18825	COG1704	LemA family
VroAM7_RS18830	COG0501	Belongs to the peptidase M48B family
VroAM7_RS18855	COG0641	radical SAM
VroAM7_RS18875	COG3111	PFAM Bacterial OB fold (BOF) protein
VroAM7_RS18880	COG1597	lipid kinase activity
VroAM7_RS18885	COG0583	DNA-binding transcription factor activity
VroAM7_RS18920	COG0714	Associated with various cellular activities
VroAM7_RS18925	COG0641	radical SAM
VroAM7_RS18930	COG3119	arylsulfatase activity
VroAM7_RS18935	COG0583	DNA-binding transcription factor activity
VroAM7_RS18945	COG3119	arylsulfatase activity
VroAM7_RS18950	COG3119	arylsulfatase activity
VroAM7_RS18970	COG0515	serine threonine protein kinase
VroAM7_RS18970	COG1262	PFAM Formylglycine-generating sulfatase enzyme
VroAM7_RS18990	COG2205	protein histidine kinase activity
VroAM7_RS18990	COG2198	Histidine kinase
VroAM7_RS18990	COG0784	Response regulator, receiver
VroAM7_RS18995	COG1879	ABC-type sugar transport system periplasmic component
VroAM7_RS19000	COG1803	Methylglyoxal synthase
VroAM7_RS19005	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
VroAM7_RS19015	COG0840	transmembrane signaling receptor activity
VroAM7_RS19035	COG2195	Cleaves the N-terminal amino acid of tripeptides
VroAM7_RS19050	COG4989	oxidoreductase activity
VroAM7_RS19075	COG1914	H( )-stimulated, divalent metal cation uptake system
VroAM7_RS19095	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
VroAM7_RS19115	COG2897	thiosulfate sulfurtransferase activity
VroAM7_RS19140	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
VroAM7_RS19145	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
VroAM7_RS19150	COG0840	transmembrane signaling receptor activity
VroAM7_RS19155	COG2814	Major facilitator Superfamily
VroAM7_RS19160	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
VroAM7_RS19175	COG1612	heme a metabolic process
VroAM7_RS19200	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
VroAM7_RS19215	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
VroAM7_RS19225	COG1280	lysine exporter protein (LysE YggA)
VroAM7_RS19245	COG0179	Fumarylacetoacetate (FAA) hydrolase
VroAM7_RS19255	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
VroAM7_RS19260	COG0697	spore germination
VroAM7_RS19280	COG2814	Major facilitator Superfamily
VroAM7_RS19285	COG0583	DNA-binding transcription factor activity
VroAM7_RS19290	COG5001	Diguanylate cyclase
VroAM7_RS19295	COG0739	heme binding
VroAM7_RS19320	COG3314	Sporulation integral membrane protein YlbJ
VroAM7_RS19330	COG0814	amino acid
VroAM7_RS19335	COG0840	transmembrane signaling receptor activity
VroAM7_RS19340	COG0366	Alpha amylase catalytic
VroAM7_RS19345	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
VroAM7_RS19350	COG0784	Response regulator, receiver
VroAM7_RS19350	COG0835	chemotaxis
VroAM7_RS19360	COG0748	coenzyme F420 binding
VroAM7_RS19365	COG3721	Heme iron utilization protein
VroAM7_RS19375	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
VroAM7_RS19380	COG0811	peptide transport
VroAM7_RS19385	COG0848	biopolymer transport protein
VroAM7_RS19395	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VroAM7_RS19400	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
VroAM7_RS19440	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
VroAM7_RS19450	COG0633	Ferredoxin
VroAM7_RS19450	COG3217	Mosc domain protein beta barrel domain protein
VroAM7_RS19450	COG0633	Ferredoxin
VroAM7_RS19450	COG3217	Mosc domain protein beta barrel domain protein
VroAM7_RS19455	COG0401	homolog of Blt101
VroAM7_RS19470	COG2354	Protein conserved in bacteria
VroAM7_RS19480	COG4753	response regulator
VroAM7_RS19480	COG2207	Transcriptional regulator
VroAM7_RS19500	COG3833	ABC-type maltose transport systems, permease component
VroAM7_RS19505	COG1175	transmembrane transport
VroAM7_RS19520	COG3842	ATPase activity
VroAM7_RS19525	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
VroAM7_RS19540	COG0489	protein tyrosine kinase activity
VroAM7_RS19540	COG3206	protein involved in exopolysaccharide biosynthesis
VroAM7_RS19545	COG0438	transferase activity, transferring glycosyl groups
VroAM7_RS19580	COG1309	transcriptional regulator
VroAM7_RS19585	COG2130	NADP-dependent
VroAM7_RS19595	COG0753	catalase activity
VroAM7_RS19600	COG2084	Dehydrogenase
VroAM7_RS19610	COG0583	DNA-binding transcription factor activity
VroAM7_RS19615	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VroAM7_RS19620	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VroAM7_RS19630	COG2207	Transcriptional regulator
VroAM7_RS19635	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
VroAM7_RS19635	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VroAM7_RS19635	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VroAM7_RS19670	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
VroAM7_RS19690	COG1131	(ABC) transporter
VroAM7_RS19695	COG0842	Transport permease protein
VroAM7_RS19715	COG3383	formate dehydrogenase (NAD+) activity
VroAM7_RS19735	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
VroAM7_RS19770	COG0456	acetyltransferase
VroAM7_RS19785	COG0494	nUDIX hydrolase
VroAM7_RS19800	COG1858	cytochrome C peroxidase
VroAM7_RS19810	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VroAM7_RS19815	COG1505	serine-type exopeptidase activity
VroAM7_RS19820	COG0488	(ABC) transporter
VroAM7_RS19825	COG1720	tRNA m6t6A37 methyltransferase activity
VroAM7_RS19845	COG2814	Major facilitator Superfamily
VroAM7_RS19860	COG0583	DNA-binding transcription factor activity
VroAM7_RS19865	COG0589	response to stress
VroAM7_RS19895	COG0523	cobalamin synthesis protein
VroAM7_RS19905	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
VroAM7_RS19915	COG4667	esterase of the alpha-beta hydrolase superfamily
VroAM7_RS19925	COG1741	Belongs to the pirin family
VroAM7_RS19930	COG1278	Cold shock
VroAM7_RS19945	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
VroAM7_RS19980	COG2226	methyltransferase
VroAM7_RS19990	COG3706	GGDEF domain
VroAM7_RS19995	COG1686	Belongs to the peptidase S11 family
VroAM7_RS20000	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
VroAM7_RS20005	COG2249	NAD(P)H dehydrogenase (quinone) activity
VroAM7_RS20010	COG0583	DNA-binding transcription factor activity
VroAM7_RS20015	COG0625	glutathione transferase activity
VroAM7_RS20025	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
VroAM7_RS20030	COG1621	beta-fructofuranosidase activity
VroAM7_RS20035	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VroAM7_RS20040	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VroAM7_RS20040	COG1263	PTS System
VroAM7_RS20060	COG4771	TonB-dependent receptor
VroAM7_RS20065	COG0583	DNA-binding transcription factor activity
VroAM7_RS20070	COG1028	Short-chain dehydrogenase reductase Sdr
VroAM7_RS20095	COG3746	phosphate-selective porin O and P
VroAM7_RS20115	COG1028	Short-chain dehydrogenase reductase Sdr
VroAM7_RS20125	COG0583	DNA-binding transcription factor activity
VroAM7_RS20130	COG2207	Transcriptional regulator
VroAM7_RS20130	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
VroAM7_RS20135	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
VroAM7_RS20165	COG0513	Belongs to the DEAD box helicase family
VroAM7_RS20175	COG0583	DNA-binding transcription factor activity
VroAM7_RS20195	COG1028	Short-chain dehydrogenase reductase Sdr
VroAM7_RS20200	COG2814	Major facilitator Superfamily
VroAM7_RS20210	COG1902	pentaerythritol trinitrate reductase activity
VroAM7_RS20225	COG3122	Protein conserved in bacteria
VroAM7_RS20240	COG0583	DNA-binding transcription factor activity
VroAM7_RS20245	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
VroAM7_RS20260	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
VroAM7_RS20260	COG0574	Belongs to the PEP-utilizing enzyme family
VroAM7_RS20270	COG2197	response regulator
VroAM7_RS20275	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
VroAM7_RS20290	COG0583	DNA-binding transcription factor activity
VroAM7_RS20295	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VroAM7_RS20305	COG1538	Outer membrane efflux protein
VroAM7_RS20310	COG0786	glutamate:sodium symporter activity
VroAM7_RS20335	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
VroAM7_RS20340	COG0318	PFAM AMP-dependent synthetase and ligase
VroAM7_RS20385	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
VroAM7_RS20405	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
VroAM7_RS20455	COG4948	Mandelate Racemase Muconate Lactonizing
VroAM7_RS20465	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
VroAM7_RS20475	COG0348	domain, Protein
VroAM7_RS20480	COG0437	4 iron, 4 sulfur cluster binding
VroAM7_RS20485	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VroAM7_RS20505	COG0840	transmembrane signaling receptor activity
VroAM7_RS20510	COG0840	transmembrane signaling receptor activity
VroAM7_RS20515	COG1067	ATP-dependent peptidase activity
VroAM7_RS20525	COG4172	Belongs to the ABC transporter superfamily
VroAM7_RS20530	COG1505	serine-type exopeptidase activity
VroAM7_RS20535	COG0583	DNA-binding transcription factor activity
VroAM7_RS20540	COG1620	l-lactate permease
VroAM7_RS20545	COG1304	FMN binding
VroAM7_RS20560	COG0668	transmembrane transport
VroAM7_RS20595	COG1342	Belongs to the UPF0251 family
VroAM7_RS20605	COG4176	ABC-type proline glycine betaine transport system permease component
VroAM7_RS20610	COG4175	Glycine betaine
VroAM7_RS20610	COG3448	diguanylate cyclase activity
VroAM7_RS20625	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
VroAM7_RS20630	COG0589	response to stress
VroAM7_RS20635	COG0583	DNA-binding transcription factor activity
VroAM7_RS20685	COG1335	isochorismatase
VroAM7_RS20705	COG1349	DNA-binding transcription factor activity
VroAM7_RS20710	COG0346	lactoylglutathione lyase activity
VroAM7_RS20715	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VroAM7_RS20715	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VroAM7_RS20730	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VroAM7_RS20735	COG2070	2-Nitropropane dioxygenase
VroAM7_RS20740	COG0531	amino acid
VroAM7_RS20745	COG4302	ethanolamine ammonia-lyase activity
VroAM7_RS20760	COG4771	TonB-dependent receptor
VroAM7_RS20765	COG2382	esterase
VroAM7_RS20770	COG2207	Transcriptional regulator
VroAM7_RS20785	COG1280	lysine exporter protein (LysE YggA)
VroAM7_RS20790	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
VroAM7_RS20805	COG3226	Transcriptional regulator
VroAM7_RS20820	COG0583	DNA-binding transcription factor activity
VroAM7_RS20835	COG0435	Glutathione S-transferase
VroAM7_RS20840	COG0431	NADPH-dependent FMN reductase
VroAM7_RS20845	COG0583	DNA-binding transcription factor activity
VroAM7_RS20850	COG4628	conserved protein (DUF2132)
VroAM7_RS20855	COG0488	(ABC) transporter
VroAM7_RS20860	COG0346	lactoylglutathione lyase activity
VroAM7_RS20865	COG0384	phenazine biosynthesis protein PhzF
VroAM7_RS20870	COG0251	oxidation-reduction process
VroAM7_RS20890	COG1882	Formate acetyltransferase
VroAM7_RS20895	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
VroAM7_RS20900	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
VroAM7_RS20905	COG2199	diguanylate cyclase activity
VroAM7_RS20920	COG0454	-acetyltransferase
VroAM7_RS20930	COG2814	Major facilitator Superfamily
VroAM7_RS20975	COG0628	permease
VroAM7_RS20980	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
VroAM7_RS20985	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
VroAM7_RS21005	COG3033	Beta-eliminating lyase
VroAM7_RS21020	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
VroAM7_RS21025	COG0579	oxidoreductase
VroAM7_RS21050	COG1114	Component of the transport system for branched-chain amino acids
VroAM7_RS21060	COG4191	Histidine kinase
VroAM7_RS21095	COG0583	DNA-binding transcription factor activity
VroAM7_RS21120	COG0189	ligase activity
VroAM7_RS21125	COG4067	protein conserved in archaea
VroAM7_RS21125	COG0189	ligase activity
VroAM7_RS21135	COG1166	arginine decarboxylase activity
VroAM7_RS21140	COG0010	Belongs to the arginase family
VroAM7_RS21145	COG2814	Major facilitator Superfamily
VroAM7_RS21150	COG1770	oligopeptidase
VroAM7_RS21165	COG1108	ABC-type Mn2 Zn2 transport systems permease components
VroAM7_RS21170	COG1121	(ABC) transporter
VroAM7_RS21175	COG0803	Belongs to the bacterial solute-binding protein 9 family
VroAM7_RS21220	COG0848	biopolymer transport protein
VroAM7_RS21225	COG0811	peptide transport
VroAM7_RS21230	COG0811	peptide transport
VroAM7_RS21250	COG0745	RESPONSE REGULATOR receiver
VroAM7_RS21255	COG0039	L-malate dehydrogenase activity
VroAM7_RS21260	COG0584	glycerophosphoryl diester phosphodiesterase
VroAM7_RS21270	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
VroAM7_RS21335	COG0312	modulator of DNA gyrase
VroAM7_RS21340	COG0312	modulator of DNA gyrase
VroAM7_RS21345	COG0351	phosphomethylpyrimidine kinase
VroAM7_RS21350	COG1116	anion transmembrane transporter activity
VroAM7_RS21355	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
VroAM7_RS21360	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
VroAM7_RS21365	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
VroAM7_RS21380	COG0671	phosphoesterase, PA-phosphatase related
VroAM7_RS21390	COG1028	Short-chain dehydrogenase reductase Sdr
VroAM7_RS21410	COG0456	acetyltransferase
VroAM7_RS21415	COG3157	Type VI secretion system effector, Hcp
VroAM7_RS21460	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
VroAM7_RS21465	COG1929	Belongs to the glycerate kinase type-1 family
VroAM7_RS21495	COG0546	phosphoglycolate phosphatase activity
VroAM7_RS21550	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
VroAM7_RS21550	COG3408	Glycogen debranching enzyme
VroAM7_RS21565	COG2814	Major facilitator Superfamily
VroAM7_RS21580	COG2358	TRAP transporter, solute receptor (TAXI family
VroAM7_RS21585	COG3047	cAMP biosynthetic process
VroAM7_RS21590	COG1357	PFAM Pentapeptide repeats (8 copies)
VroAM7_RS21605	COG0534	Mate efflux family protein
VroAM7_RS21620	COG2076	Multidrug Resistance protein
VroAM7_RS21665	COG0583	DNA-binding transcription factor activity
VroAM7_RS21675	COG2162	N-hydroxyarylamine O-acetyltransferase activity
VroAM7_RS21680	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
VroAM7_RS21695	COG3152	Membrane
VroAM7_RS21715	COG0561	phosphatase activity
VroAM7_RS21720	COG0564	pseudouridine synthase activity
VroAM7_RS21740	COG0406	alpha-ribazole phosphatase activity
VroAM7_RS21785	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
VroAM7_RS21815	COG0534	Mate efflux family protein
VroAM7_RS21820	COG1472	Belongs to the glycosyl hydrolase 3 family
VroAM7_RS21840	COG1609	Transcriptional regulator
VroAM7_RS21850	COG4608	Belongs to the ABC transporter superfamily
VroAM7_RS21855	COG0444	Belongs to the ABC transporter superfamily
VroAM7_RS21860	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VroAM7_RS21870	COG0747	negative chemotaxis
VroAM7_RS21880	COG1609	Transcriptional regulator
VroAM7_RS21885	COG3842	ATPase activity
VroAM7_RS21890	COG2723	6-phospho-beta-galactosidase activity
VroAM7_RS21895	COG0395	ABC-type sugar transport system, permease component
VroAM7_RS21910	COG1609	Transcriptional regulator
VroAM7_RS21920	COG5001	Diguanylate cyclase
VroAM7_RS21930	COG3123	guanosine phosphorylase activity
VroAM7_RS21970	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
VroAM7_RS21980	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
VroAM7_RS21985	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
VroAM7_RS22025	COG0786	glutamate:sodium symporter activity
VroAM7_RS22030	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
VroAM7_RS22035	COG1131	(ABC) transporter
VroAM7_RS22050	COG0786	glutamate:sodium symporter activity
VroAM7_RS22085	COG1028	Short-chain dehydrogenase reductase Sdr
VroAM7_RS22120	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
VroAM7_RS22130	COG3279	Response regulator of the LytR AlgR family
VroAM7_RS22135	COG3275	phosphorelay sensor kinase activity
VroAM7_RS22155	COG1136	(ABC) transporter
VroAM7_RS22165	COG0583	DNA-binding transcription factor activity
VroAM7_RS22170	COG1566	PFAM secretion protein HlyD family protein
VroAM7_RS22180	COG0772	Belongs to the SEDS family
VroAM7_RS22205	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
VroAM7_RS22205	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
VroAM7_RS22215	COG0444	Belongs to the ABC transporter superfamily
VroAM7_RS22220	COG4608	Belongs to the ABC transporter superfamily
VroAM7_RS22245	COG1444	tRNA N-acetyltransferase activity
VroAM7_RS22305	COG2204	response regulator
VroAM7_RS22315	COG0259	pyridoxamine-phosphate oxidase activity
VroAM7_RS22320	COG1132	(ABC) transporter
VroAM7_RS22335	COG3655	Transcriptional regulator
VroAM7_RS22350	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
VroAM7_RS22360	COG1595	DNA-templated transcription, initiation
VroAM7_RS22370	COG0667	Aldo Keto reductase
VroAM7_RS22375	COG0513	Belongs to the DEAD box helicase family
VroAM7_RS22380	COG3713	MltA-interacting MipA family protein
VroAM7_RS22390	COG2258	MOSC domain
VroAM7_RS22405	COG1522	sequence-specific DNA binding
VroAM7_RS22420	COG0840	transmembrane signaling receptor activity
VroAM7_RS22440	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
VroAM7_RS22445	COG0583	DNA-binding transcription factor activity
VroAM7_RS22475	COG3634	alkyl hydroperoxide reductase activity
VroAM7_RS22485	COG1846	Transcriptional regulator
VroAM7_RS22490	COG1764	response to oxidative stress
VroAM7_RS22520	COG0577	efflux transmembrane transporter activity
VroAM7_RS22525	COG1136	(ABC) transporter
VroAM7_RS22535	COG1355	regulation of microtubule-based process
VroAM7_RS22555	COG0826	peptidase U32
VroAM7_RS22565	COG4772	TonB-dependent receptor
VroAM7_RS22570	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
VroAM7_RS22575	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VroAM7_RS22580	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VroAM7_RS22585	COG1120	ATPase activity
VroAM7_RS22590	COG0840	transmembrane signaling receptor activity
VroAM7_RS22595	COG0612	Peptidase, M16
VroAM7_RS22610	COG0739	heme binding
VroAM7_RS22640	COG4604	ABC transporter, ATP-binding protein
VroAM7_RS22645	COG4605	iron ion homeostasis
VroAM7_RS22650	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VroAM7_RS22655	COG4607	ABC-type enterochelin transport system periplasmic component
VroAM7_RS22660	COG0583	DNA-binding transcription factor activity
VroAM7_RS22665	COG4771	TonB-dependent receptor
VroAM7_RS22675	COG3214	Protein conserved in bacteria
VroAM7_RS22680	COG2814	Major facilitator Superfamily
VroAM7_RS22695	COG2203	Gaf domain
VroAM7_RS22695	COG2199	diguanylate cyclase activity
VroAM7_RS22725	COG2356	endonuclease I
VroAM7_RS22755	COG1982	Orn Lys Arg decarboxylase major
VroAM7_RS22760	COG0531	amino acid
VroAM7_RS22775	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
VroAM7_RS22780	COG1162	GTPase activity
VroAM7_RS22795	COG1999	signal sequence binding
VroAM7_RS22815	COG0058	SHG alpha-glucan phosphorylase activity
VroAM7_RS22820	COG1640	4-alpha-glucanotransferase
VroAM7_RS22825	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
VroAM7_RS22830	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
VroAM7_RS22835	COG0366	Alpha amylase catalytic
VroAM7_RS22850	COG3366	ferrous iron transmembrane transporter activity
VroAM7_RS22855	COG0700	Nucleoside recognition
VroAM7_RS22860	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
VroAM7_RS22865	COG3339	Conserved Protein
VroAM7_RS22870	COG1301	dicarboxylic acid transport
VroAM7_RS22905	COG0583	DNA-binding transcription factor activity
VroAM7_RS22930	COG2095	MarC family integral membrane protein
VroAM7_RS22935	COG0840	transmembrane signaling receptor activity
VroAM7_RS22940	COG4667	esterase of the alpha-beta hydrolase superfamily
VroAM7_RS22950	COG0415	Belongs to the DNA photolyase family
VroAM7_RS22965	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
VroAM7_RS22970	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
VroAM7_RS22990	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
VroAM7_RS23005	COG1686	Belongs to the peptidase S11 family
VroAM7_RS23030	COG0583	DNA-binding transcription factor activity
VroAM7_RS23035	COG4628	conserved protein (DUF2132)
VroAM7_RS23045	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
VroAM7_RS23065	COG3706	GGDEF domain
VroAM7_RS23085	COG3706	GGDEF domain
VroAM7_RS23090	COG0415	Belongs to the DNA photolyase family
VroAM7_RS23095	COG3046	protein related to deoxyribodipyrimidine photolyase
VroAM7_RS23110	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VroAM7_RS23110	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VroAM7_RS23115	COG1765	OsmC-like protein
VroAM7_RS23160	COG1011	Hydrolase
VroAM7_RS23190	COG1511	domain protein
VroAM7_RS23190	COG3264	Mechanosensitive ion channel
VroAM7_RS23200	COG3240	lipase activity
VroAM7_RS23220	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
VroAM7_RS23230	COG1840	ABC-type Fe3 transport system, periplasmic component
VroAM7_RS23235	COG3842	ATPase activity
VroAM7_RS23260	COG2990	Protein conserved in bacteria
VroAM7_RS23270	COG2866	Carboxypeptidase
VroAM7_RS23300	COG3104	oligopeptide transport
VroAM7_RS23305	COG1760	l-serine dehydratase
VroAM7_RS23330	COG0741	lytic transglycosylase activity
VroAM7_RS23330	COG1388	LysM domain
VroAM7_RS23350	COG1815	bacterial-type flagellum-dependent cell motility
VroAM7_RS23355	COG1558	bacterial-type flagellum-dependent cell motility
VroAM7_RS23360	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
VroAM7_RS23365	COG1749	Flagellar hook protein flgE
VroAM7_RS23370	COG4787	bacterial-type flagellum-dependent cell motility
VroAM7_RS23375	COG4786	Flagellar basal body rod
VroAM7_RS23380	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
VroAM7_RS23385	COG1706	bacterial-type flagellum-dependent cell motility
VroAM7_RS23395	COG4786	Flagellar basal body rod
VroAM7_RS23395	COG1256	bacterial-type flagellum assembly
VroAM7_RS23470	COG1360	Flagellar Motor Protein
VroAM7_RS23475	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
VroAM7_RS23480	COG1191	sigma factor activity
VroAM7_RS23485	COG1580	Controls the rotational direction of flagella during chemotaxis
VroAM7_RS23505	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
VroAM7_RS23510	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VroAM7_RS23535	COG1987	bacterial-type flagellum assembly
VroAM7_RS23595	COG2200	EAL domain
VroAM7_RS23645	COG0346	lactoylglutathione lyase activity
VroAM7_RS23670	COG0745	RESPONSE REGULATOR receiver
VroAM7_RS23680	COG0156	8-amino-7-oxononanoate synthase activity
VroAM7_RS23685	COG1063	alcohol dehydrogenase
VroAM7_RS23710	COG1122	ATPase activity
VroAM7_RS23720	COG1566	PFAM secretion protein HlyD family protein
VroAM7_RS23750	COG0813	purine-nucleoside phosphorylase activity
VroAM7_RS23760	COG3272	Protein of unknown function (DUF1722)
VroAM7_RS23765	COG0789	Transcriptional regulator
VroAM7_RS23770	COG0415	Belongs to the DNA photolyase family
VroAM7_RS23775	COG1388	LysM domain
VroAM7_RS23775	COG1376	ErfK ybiS ycfS ynhG family protein
VroAM7_RS23865	COG4695	Portal protein
VroAM7_RS24010	COG0513	Belongs to the DEAD box helicase family
VroAM7_RS24020	COG1770	oligopeptidase
VroAM7_RS24025	COG4771	TonB-dependent receptor
VroAM7_RS24065	COG0573	inorganic phosphate transmembrane transporter activity
VroAM7_RS24070	COG0581	inorganic phosphate transmembrane transporter activity
VroAM7_RS24075	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
VroAM7_RS24090	COG2304	oxidoreductase activity
VroAM7_RS24110	COG0714	Associated with various cellular activities
VroAM7_RS24115	COG0840	transmembrane signaling receptor activity
VroAM7_RS24125	COG2197	response regulator
VroAM7_RS24145	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VroAM7_RS24150	COG0110	maltose O-acetyltransferase activity
VroAM7_RS24155	COG1028	Short-chain dehydrogenase reductase Sdr
VroAM7_RS24175	COG3706	GGDEF domain
VroAM7_RS24175	COG4251	negative regulation of phosphorylation
VroAM7_RS24175	COG2203	Gaf domain
VroAM7_RS24175	COG5001	Diguanylate cyclase
VroAM7_RS24190	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
VroAM7_RS24205	COG1252	NADH dehydrogenase
VroAM7_RS24210	COG1301	dicarboxylic acid transport
VroAM7_RS24220	COG1881	PFAM PEBP family protein
VroAM7_RS24230	COG0798	PFAM Bile acid sodium symporter
VroAM7_RS24245	COG1733	regulation of RNA biosynthetic process
VroAM7_RS24260	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
VroAM7_RS24265	COG2213	PTS system mannitol-specific
VroAM7_RS24270	COG1063	alcohol dehydrogenase
VroAM7_RS24280	COG1072	(Pantothenic acid kinase))
VroAM7_RS24285	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
VroAM7_RS24335	COG0583	DNA-binding transcription factor activity
VroAM7_RS24355	COG0583	DNA-binding transcription factor activity
VroAM7_RS24375	COG2814	Major facilitator Superfamily
VroAM7_RS24385	COG1335	isochorismatase
VroAM7_RS24400	COG2194	sulfuric ester hydrolase activity
VroAM7_RS24405	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
VroAM7_RS24415	COG2205	protein histidine kinase activity
VroAM7_RS24420	COG0745	RESPONSE REGULATOR receiver
VroAM7_RS24430	COG4221	oxidoreductase activity
VroAM7_RS24445	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
VroAM7_RS24465	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
VroAM7_RS24475	COG2814	Major facilitator Superfamily
VroAM7_RS24490	COG1418	mRNA catabolic process
VroAM7_RS24505	COG0402	S-adenosylhomocysteine deaminase activity
VroAM7_RS24510	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
VroAM7_RS24515	COG2239	Acts as a magnesium transporter
VroAM7_RS24520	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
VroAM7_RS24525	COG1566	PFAM secretion protein HlyD family protein
VroAM7_RS24545	COG0745	RESPONSE REGULATOR receiver
VroAM7_RS24550	COG2205	protein histidine kinase activity
VroAM7_RS24565	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VroAM7_RS24580	COG0531	amino acid
VroAM7_RS24615	COG2205	protein histidine kinase activity
VroAM7_RS24615	COG0784	Response regulator, receiver
VroAM7_RS24615	COG5002	protein histidine kinase activity
VroAM7_RS24620	COG0673	inositol 2-dehydrogenase activity
VroAM7_RS24630	COG2926	Belongs to the UPF0265 family
VroAM7_RS24650	COG1879	ABC-type sugar transport system periplasmic component
VroAM7_RS24700	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
VroAM7_RS24705	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
VroAM7_RS24715	COG1280	lysine exporter protein (LysE YggA)
VroAM7_RS24725	COG0183	Belongs to the thiolase family
VroAM7_RS24745	COG3005	denitrification pathway
VroAM7_RS24755	COG0243	molybdopterin cofactor binding
VroAM7_RS24765	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
VroAM7_RS24770	COG3850	Histidine kinase
VroAM7_RS24775	COG2197	response regulator
VroAM7_RS24790	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
VroAM7_RS24790	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
VroAM7_RS24820	COG1061	Type III restriction enzyme res subunit
VroAM7_RS24855	COG2204	response regulator
VroAM7_RS24865	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
VroAM7_RS24940	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
VroAM7_RS24945	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
VroAM7_RS24965	COG4251	negative regulation of phosphorylation
VroAM7_RS24965	COG3706	GGDEF domain
VroAM7_RS24965	COG2203	Gaf domain
VroAM7_RS24965	COG5001	Diguanylate cyclase
VroAM7_RS25005	COG2199	diguanylate cyclase activity
VroAM7_RS25005	COG2200	EAL domain
VroAM7_RS25020	COG2165	general secretion pathway protein
VroAM7_RS25025	COG0402	S-adenosylhomocysteine deaminase activity
VroAM7_RS25030	COG0076	glutamate decarboxylase activity
VroAM7_RS25060	COG4176	ABC-type proline glycine betaine transport system permease component
VroAM7_RS25065	COG0517	IMP dehydrogenase activity
VroAM7_RS25065	COG4175	Glycine betaine
VroAM7_RS25080	COG0330	HflC and HflK could
VroAM7_RS25090	COG2202	Pas domain
VroAM7_RS25090	COG2199	diguanylate cyclase activity
VroAM7_RS25090	COG2200	EAL domain
VroAM7_RS25095	COG2197	response regulator
VroAM7_RS25100	COG5001	Diguanylate cyclase
VroAM7_RS25100	COG4251	negative regulation of phosphorylation
VroAM7_RS25100	COG3706	GGDEF domain
VroAM7_RS25100	COG2203	Gaf domain
VroAM7_RS25105	COG2205	protein histidine kinase activity
VroAM7_RS25105	COG0784	Response regulator, receiver
VroAM7_RS25130	COG1619	proteins homologs of microcin C7 resistance protein MccF
VroAM7_RS25135	COG2133	pyrroloquinoline quinone binding
VroAM7_RS25140	COG1454	alcohol dehydrogenase
VroAM7_RS25145	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
VroAM7_RS25170	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
VroAM7_RS25175	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
VroAM7_RS25185	COG3186	Phenylalanine-4-hydroxylase
VroAM7_RS25220	COG3530	Putative quorum-sensing-regulated virulence factor
VroAM7_RS25255	COG0523	cobalamin synthesis protein
VroAM7_RS25260	COG0513	Belongs to the DEAD box helicase family
VroAM7_RS25280	COG2200	EAL domain
VroAM7_RS25285	COG1119	ATPase activity
VroAM7_RS25300	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
VroAM7_RS25315	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
VroAM7_RS25320	COG0513	Belongs to the DEAD box helicase family
VroAM7_RS25325	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
VroAM7_RS25355	COG3278	Belongs to the heme-copper respiratory oxidase family
VroAM7_RS25380	COG1024	Enoyl-CoA hydratase
VroAM7_RS25385	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
VroAM7_RS25390	COG1960	acyl-CoA dehydrogenase activity
VroAM7_RS25400	COG0183	Belongs to the thiolase family
VroAM7_RS25415	COG1024	Enoyl-CoA hydratase
VroAM7_RS25420	COG1024	Enoyl-CoA hydratase
VroAM7_RS25430	COG1028	Short-chain dehydrogenase reductase Sdr
VroAM7_RS25450	COG0446	pyridine nucleotide-disulphide oxidoreductase
VroAM7_RS25450	COG1902	pentaerythritol trinitrate reductase activity
VroAM7_RS25455	COG0583	DNA-binding transcription factor activity
VroAM7_RS25465	COG1012	belongs to the aldehyde dehydrogenase family
VroAM7_RS25475	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
VroAM7_RS25505	COG1126	abc transporter atp-binding protein
VroAM7_RS25510	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VroAM7_RS25515	COG4215	(ABC) transporter
VroAM7_RS25520	COG4160	amino acid transport
VroAM7_RS25550	COG1538	Outer membrane efflux protein
VroAM7_RS25600	COG2249	NAD(P)H dehydrogenase (quinone) activity
VroAM7_RS25605	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
VroAM7_RS25620	COG0443	Heat shock 70 kDa protein
VroAM7_RS25640	COG0745	RESPONSE REGULATOR receiver
VroAM7_RS25645	COG0003	Pfam Anion-transporting ATPase
VroAM7_RS25650	COG0545	Peptidyl-prolyl cis-trans isomerase
VroAM7_RS25660	COG2885	chlorophyll binding
VroAM7_RS25680	COG1278	Cold shock
VroAM7_RS25685	COG3036	rescue of stalled ribosome
VroAM7_RS25695	COG2199	diguanylate cyclase activity
VroAM7_RS25695	COG2203	Gaf domain
VroAM7_RS25715	COG1136	(ABC) transporter
VroAM7_RS25730	COG0783	Belongs to the Dps family
VroAM7_RS25810	COG3829	transcription factor binding
VroAM7_RS25840	COG3501	Rhs element vgr protein
VroAM7_RS25850	COG0666	response to abiotic stimulus
VroAM7_RS25885	COG3209	COG3209 Rhs family protein
VroAM7_RS26310	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
VroAM7_RS26410	COG0210	DNA helicase
VroAM7_RS26500	COG1196	nuclear chromosome segregation
VroAM7_RS26520	COG0330	HflC and HflK could
VroAM7_RS26540	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
VroAM7_RS26840	COG3842	ATPase activity
VroAM7_RS26950	COG1192	Involved in chromosome partitioning
VroAM7_RS26960	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
VroAM7_RS26970	COG0732	type I restriction modification DNA specificity domain
VroAM7_RS26975	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
VroAM7_RS27000	COG2197	response regulator
VroAM7_RS27025	COG0583	DNA-binding transcription factor activity
VroAM7_RS27045	COG2313	pseudouridylate synthase activity
VroAM7_RS27075	COG4251	negative regulation of phosphorylation
VroAM7_RS27080	COG2197	response regulator
VroAM7_RS27090	COG4584	PFAM Integrase catalytic
VroAM7_RS27095	COG1484	DNA-dependent DNA replication
VroAM7_RS27100	COG5001	Diguanylate cyclase
VroAM7_RS27100	COG3300	MHYT domain
VroAM7_RS27110	COG3706	GGDEF domain