locus-tag	class	description
CEQ48_RS00035	COG0023	Translation Initiation Factor
CEQ48_RS00055	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CEQ48_RS00055	COG0045	succinate-CoA ligase (ADP-forming) activity
CEQ48_RS00055	COG1042	CoA-binding domain protein
CEQ48_RS00060	COG0583	DNA-binding transcription factor activity
CEQ48_RS00065	COG4771	TonB-dependent receptor
CEQ48_RS00085	COG2050	protein possibly involved in aromatic compounds catabolism
CEQ48_RS00110	COG0625	glutathione transferase activity
CEQ48_RS00125	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CEQ48_RS00130	COG4172	Belongs to the ABC transporter superfamily
CEQ48_RS00135	COG4239	(ABC) transporter, permease
CEQ48_RS00140	COG4174	ABC transporter (Permease)
CEQ48_RS00145	COG4166	transmembrane transport
CEQ48_RS00170	COG3104	oligopeptide transport
CEQ48_RS00190	COG3842	ATPase activity
CEQ48_RS00200	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CEQ48_RS00205	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CEQ48_RS00210	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CEQ48_RS00215	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CEQ48_RS00220	COG1011	Hydrolase
CEQ48_RS00230	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
CEQ48_RS00235	COG1970	mechanosensitive ion channel activity
CEQ48_RS00240	COG2759	Belongs to the formate--tetrahydrofolate ligase family
CEQ48_RS00245	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CEQ48_RS00245	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CEQ48_RS00250	COG0302	gtp cyclohydrolase
CEQ48_RS00260	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CEQ48_RS00270	COG2897	thiosulfate sulfurtransferase activity
CEQ48_RS00280	COG2390	Transcriptional regulator
CEQ48_RS00295	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CEQ48_RS00315	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CEQ48_RS00345	COG0583	DNA-binding transcription factor activity
CEQ48_RS00350	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CEQ48_RS00375	COG2391	methyltransferase activity
CEQ48_RS00385	COG0640	Transcriptional regulator
CEQ48_RS00405	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
CEQ48_RS00430	COG2801	Transposase and inactivated derivatives
CEQ48_RS00440	COG0456	acetyltransferase
CEQ48_RS00455	COG2801	Transposase and inactivated derivatives
CEQ48_RS00460	COG0346	lactoylglutathione lyase activity
CEQ48_RS00475	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CEQ48_RS00590	COG2801	Transposase and inactivated derivatives
CEQ48_RS00620	COG0456	acetyltransferase
CEQ48_RS00640	COG0346	lactoylglutathione lyase activity
CEQ48_RS00710	COG0346	lactoylglutathione lyase activity
CEQ48_RS00775	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CEQ48_RS00790	COG1418	mRNA catabolic process
CEQ48_RS00835	COG0110	maltose O-acetyltransferase activity
CEQ48_RS00890	COG2801	Transposase and inactivated derivatives
CEQ48_RS00955	COG0384	phenazine biosynthesis protein PhzF
CEQ48_RS00965	COG0456	acetyltransferase
CEQ48_RS00995	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CEQ48_RS01000	COG0454	-acetyltransferase
CEQ48_RS01065	COG0456	acetyltransferase
CEQ48_RS01095	COG2801	Transposase and inactivated derivatives
CEQ48_RS01340	COG0384	phenazine biosynthesis protein PhzF
CEQ48_RS01415	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CEQ48_RS01420	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CEQ48_RS01435	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CEQ48_RS01450	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CEQ48_RS01455	COG0509	glycine decarboxylation via glycine cleavage system
CEQ48_RS01460	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CEQ48_RS01460	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CEQ48_RS01465	COG3338	carbonate dehydratase activity
CEQ48_RS01480	COG1686	Belongs to the peptidase S11 family
CEQ48_RS01495	COG1414	Transcriptional regulator
CEQ48_RS01505	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CEQ48_RS01510	COG0601	transmembrane transport
CEQ48_RS01525	COG0641	radical SAM
CEQ48_RS01530	COG3119	arylsulfatase activity
CEQ48_RS01535	COG3119	arylsulfatase activity
CEQ48_RS01540	COG2199	diguanylate cyclase activity
CEQ48_RS01560	COG1028	Short-chain dehydrogenase reductase Sdr
CEQ48_RS01565	COG1085	galactose-1-phosphate uridylyltransferase
CEQ48_RS01570	COG0800	Aldolase
CEQ48_RS01575	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CEQ48_RS01595	COG1166	arginine decarboxylase activity
CEQ48_RS01605	COG2239	Acts as a magnesium transporter
CEQ48_RS01615	COG0534	Mate efflux family protein
CEQ48_RS01625	COG2154	pterin-4-alpha-carbinolamine dehydratase
CEQ48_RS01630	COG3186	Phenylalanine-4-hydroxylase
CEQ48_RS01635	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CEQ48_RS01655	COG2264	protein methyltransferase activity
CEQ48_RS01675	COG1253	flavin adenine dinucleotide binding
CEQ48_RS01680	COG1765	OsmC-like protein
CEQ48_RS01710	COG0531	amino acid
CEQ48_RS01730	COG3279	Response regulator of the LytR AlgR family
CEQ48_RS01735	COG3275	phosphorelay sensor kinase activity
CEQ48_RS01750	COG1136	(ABC) transporter
CEQ48_RS01750	COG0577	efflux transmembrane transporter activity
CEQ48_RS01755	COG1136	(ABC) transporter
CEQ48_RS01765	COG4989	oxidoreductase activity
CEQ48_RS01770	COG0366	Alpha amylase catalytic
CEQ48_RS01775	COG3227	Zinc metalloprotease (Elastase)
CEQ48_RS01785	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CEQ48_RS01795	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CEQ48_RS01800	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CEQ48_RS01800	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CEQ48_RS01825	COG3036	rescue of stalled ribosome
CEQ48_RS01830	COG1278	Cold shock
CEQ48_RS01835	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CEQ48_RS01835	COG1017	nitric oxide dioxygenase activity
CEQ48_RS01840	COG3604	Transcriptional regulator
CEQ48_RS01850	COG2195	Cleaves the N-terminal amino acid of tripeptides
CEQ48_RS01855	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CEQ48_RS01870	COG0840	transmembrane signaling receptor activity
CEQ48_RS01875	COG0714	Associated with various cellular activities
CEQ48_RS01895	COG2304	oxidoreductase activity
CEQ48_RS01915	COG1278	Cold shock
CEQ48_RS01920	COG5001	Diguanylate cyclase
CEQ48_RS01920	COG5002	protein histidine kinase activity
CEQ48_RS01930	COG3530	Putative quorum-sensing-regulated virulence factor
CEQ48_RS01945	COG0814	amino acid
CEQ48_RS01950	COG0488	(ABC) transporter
CEQ48_RS01955	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CEQ48_RS01955	COG1017	nitric oxide dioxygenase activity
CEQ48_RS01960	COG0242	peptide deformylase activity
CEQ48_RS01970	COG0579	oxidoreductase
CEQ48_RS02010	COG2271	Major facilitator Superfamily
CEQ48_RS02015	COG0584	glycerophosphoryl diester phosphodiesterase
CEQ48_RS02020	COG1609	Transcriptional regulator
CEQ48_RS02025	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CEQ48_RS02030	COG1879	ABC-type sugar transport system periplasmic component
CEQ48_RS02035	COG1172	Belongs to the binding-protein-dependent transport system permease family
CEQ48_RS02040	COG1129	ABC transporter
CEQ48_RS02045	COG1869	D-ribose catabolic process
CEQ48_RS02060	COG3409	Peptidoglycan-binding domain 1 protein
CEQ48_RS02060	COG3501	Rhs element vgr protein
CEQ48_RS02090	COG3829	transcription factor binding
CEQ48_RS02155	COG0564	pseudouridine synthase activity
CEQ48_RS02165	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CEQ48_RS02170	COG2771	luxR family
CEQ48_RS02170	COG2200	EAL domain
CEQ48_RS02180	COG0673	inositol 2-dehydrogenase activity
CEQ48_RS02185	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CEQ48_RS02240	COG1301	dicarboxylic acid transport
CEQ48_RS02250	COG0700	Nucleoside recognition
CEQ48_RS02255	COG3366	ferrous iron transmembrane transporter activity
CEQ48_RS02260	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CEQ48_RS02270	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CEQ48_RS02275	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CEQ48_RS02280	COG2259	Doxx family
CEQ48_RS02305	COG0363	glucosamine-6-phosphate deaminase activity
CEQ48_RS02320	COG4580	involved in the transport of maltose and maltodextrins
CEQ48_RS02335	COG0840	transmembrane signaling receptor activity
CEQ48_RS02360	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CEQ48_RS02390	COG0513	Belongs to the DEAD box helicase family
CEQ48_RS02400	COG1132	(ABC) transporter
CEQ48_RS02410	COG1902	pentaerythritol trinitrate reductase activity
CEQ48_RS02420	COG1280	lysine exporter protein (LysE YggA)
CEQ48_RS02425	COG2207	Transcriptional regulator
CEQ48_RS02445	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CEQ48_RS02450	COG0697	spore germination
CEQ48_RS02470	COG2814	Major facilitator Superfamily
CEQ48_RS02475	COG0583	DNA-binding transcription factor activity
CEQ48_RS02480	COG3706	GGDEF domain
CEQ48_RS02480	COG4251	negative regulation of phosphorylation
CEQ48_RS02480	COG5001	Diguanylate cyclase
CEQ48_RS02480	COG2203	Gaf domain
CEQ48_RS02485	COG0739	heme binding
CEQ48_RS02495	COG0659	secondary active sulfate transmembrane transporter activity
CEQ48_RS02500	COG3314	Sporulation integral membrane protein YlbJ
CEQ48_RS02520	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CEQ48_RS02525	COG0581	inorganic phosphate transmembrane transporter activity
CEQ48_RS02530	COG0573	inorganic phosphate transmembrane transporter activity
CEQ48_RS02535	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CEQ48_RS02560	COG4771	TonB-dependent receptor
CEQ48_RS02565	COG1770	oligopeptidase
CEQ48_RS02570	COG0513	Belongs to the DEAD box helicase family
CEQ48_RS02580	COG1376	ErfK ybiS ycfS ynhG family protein
CEQ48_RS02580	COG1388	LysM domain
CEQ48_RS02585	COG0415	Belongs to the DNA photolyase family
CEQ48_RS02595	COG3272	Protein of unknown function (DUF1722)
CEQ48_RS02600	COG0813	purine-nucleoside phosphorylase activity
CEQ48_RS02635	COG0786	glutamate:sodium symporter activity
CEQ48_RS02655	COG1999	signal sequence binding
CEQ48_RS02665	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
CEQ48_RS02670	COG0671	phosphoesterase, PA-phosphatase related
CEQ48_RS02710	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
CEQ48_RS02715	COG0471	metal ion transport
CEQ48_RS02770	COG3501	Rhs element vgr protein
CEQ48_RS02780	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CEQ48_RS02785	COG1640	4-alpha-glucanotransferase
CEQ48_RS02790	COG0058	SHG alpha-glucan phosphorylase activity
CEQ48_RS02795	COG2909	trisaccharide binding
CEQ48_RS02810	COG2084	Dehydrogenase
CEQ48_RS02815	COG0217	transcriptional regulatory protein
CEQ48_RS02830	COG0444	Belongs to the ABC transporter superfamily
CEQ48_RS02835	COG4608	Belongs to the ABC transporter superfamily
CEQ48_RS02865	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CEQ48_RS02870	COG1444	tRNA N-acetyltransferase activity
CEQ48_RS02905	COG0642	Histidine kinase
CEQ48_RS02910	COG2194	sulfuric ester hydrolase activity
CEQ48_RS02920	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CEQ48_RS02925	COG0601	transmembrane transport
CEQ48_RS02950	COG0835	chemotaxis
CEQ48_RS02955	COG0835	chemotaxis
CEQ48_RS02960	COG0840	transmembrane signaling receptor activity
CEQ48_RS02965	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CEQ48_RS02990	COG0745	RESPONSE REGULATOR receiver
CEQ48_RS02995	COG0434	BtpA family
CEQ48_RS03000	COG1879	ABC-type sugar transport system periplasmic component
CEQ48_RS03005	COG1129	ABC transporter
CEQ48_RS03010	COG1172	Belongs to the binding-protein-dependent transport system permease family
CEQ48_RS03025	COG1070	Carbohydrate kinase
CEQ48_RS03030	COG1349	DNA-binding transcription factor activity
CEQ48_RS03045	COG2274	protein secretion by the type I secretion system
CEQ48_RS03075	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CEQ48_RS03100	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CEQ48_RS03150	COG2197	response regulator
CEQ48_RS03160	COG1982	Orn Lys Arg decarboxylase major
CEQ48_RS03165	COG0531	amino acid
CEQ48_RS03180	COG1901	pseudouridine methyltransferase
CEQ48_RS03195	COG4221	oxidoreductase activity
CEQ48_RS03200	COG0840	transmembrane signaling receptor activity
CEQ48_RS03210	COG2910	NAD(P)H-binding
CEQ48_RS03230	COG0655	NAD(P)H dehydrogenase (quinone) activity
CEQ48_RS03235	COG0583	DNA-binding transcription factor activity
CEQ48_RS03260	COG0673	inositol 2-dehydrogenase activity
CEQ48_RS03265	COG3722	fumarate hydratase activity
CEQ48_RS03270	COG0246	Mannitol dehydrogenase
CEQ48_RS03275	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEQ48_RS03275	COG2213	PTS system mannitol-specific
CEQ48_RS03285	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CEQ48_RS03290	COG4597	amino acid ABC transporter
CEQ48_RS03295	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CEQ48_RS03305	COG1126	abc transporter atp-binding protein
CEQ48_RS03310	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CEQ48_RS03320	COG0840	transmembrane signaling receptor activity
CEQ48_RS03335	COG1620	l-lactate permease
CEQ48_RS03340	COG0583	DNA-binding transcription factor activity
CEQ48_RS03345	COG4172	Belongs to the ABC transporter superfamily
CEQ48_RS03355	COG1067	ATP-dependent peptidase activity
CEQ48_RS03370	COG2211	Major facilitator Superfamily
CEQ48_RS03380	COG3123	guanosine phosphorylase activity
CEQ48_RS03385	COG1741	Belongs to the pirin family
CEQ48_RS03400	COG0583	DNA-binding transcription factor activity
CEQ48_RS03440	COG3706	GGDEF domain
CEQ48_RS03445	COG1846	Transcriptional regulator
CEQ48_RS03450	COG0835	chemotaxis
CEQ48_RS03450	COG0784	Response regulator, receiver
CEQ48_RS03455	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CEQ48_RS03465	COG0393	Putative heavy-metal-binding
CEQ48_RS03480	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CEQ48_RS03485	COG3842	ATPase activity
CEQ48_RS03500	COG3833	ABC-type maltose transport systems, permease component
CEQ48_RS03515	COG1349	DNA-binding transcription factor activity
CEQ48_RS03520	COG2199	diguanylate cyclase activity
CEQ48_RS03545	COG1278	Cold shock
CEQ48_RS03550	COG2354	Protein conserved in bacteria
CEQ48_RS03555	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CEQ48_RS03560	COG0418	dihydroorotase activity
CEQ48_RS03565	COG3217	Mosc domain protein beta barrel domain protein
CEQ48_RS03565	COG0633	Ferredoxin
CEQ48_RS03565	COG3217	Mosc domain protein beta barrel domain protein
CEQ48_RS03565	COG0633	Ferredoxin
CEQ48_RS03600	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CEQ48_RS03605	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CEQ48_RS03610	COG4558	Periplasmic binding protein
CEQ48_RS03615	COG0848	biopolymer transport protein
CEQ48_RS03620	COG0811	peptide transport
CEQ48_RS03625	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
CEQ48_RS03635	COG3721	Heme iron utilization protein
CEQ48_RS03640	COG0748	coenzyme F420 binding
CEQ48_RS03650	COG1858	cytochrome C peroxidase
CEQ48_RS03655	COG3835	regulator
CEQ48_RS03660	COG2610	gluconate transmembrane transporter activity
CEQ48_RS03665	COG1929	Belongs to the glycerate kinase type-1 family
CEQ48_RS03690	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CEQ48_RS03695	COG0363	glucosamine-6-phosphate deaminase activity
CEQ48_RS03700	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CEQ48_RS03705	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CEQ48_RS03725	COG0346	lactoylglutathione lyase activity
CEQ48_RS03735	COG2873	o-acetylhomoserine
CEQ48_RS03740	COG0156	8-amino-7-oxononanoate synthase activity
CEQ48_RS03745	COG1063	alcohol dehydrogenase
CEQ48_RS03760	COG0582	viral genome integration into host DNA
CEQ48_RS03790	COG1802	Transcriptional regulator
CEQ48_RS03790	COG4626	Terminase
CEQ48_RS03935	COG3833	ABC-type maltose transport systems, permease component
CEQ48_RS03945	COG0584	glycerophosphoryl diester phosphodiesterase
CEQ48_RS03995	COG1063	alcohol dehydrogenase
CEQ48_RS04005	COG1278	Cold shock
CEQ48_RS04010	COG0557	exoribonuclease II activity
CEQ48_RS04015	COG1686	Belongs to the peptidase S11 family
CEQ48_RS04025	COG3047	cAMP biosynthetic process
CEQ48_RS04045	COG0516	GMP reductase activity
CEQ48_RS04050	COG0513	Belongs to the DEAD box helicase family
CEQ48_RS04055	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CEQ48_RS04060	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CEQ48_RS04065	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CEQ48_RS04070	COG3437	response regulator, receiver
CEQ48_RS04070	COG0784	Response regulator, receiver
CEQ48_RS04075	COG4191	Histidine kinase
CEQ48_RS04075	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CEQ48_RS04085	COG1757	Na H antiporter
CEQ48_RS04090	COG2814	Major facilitator Superfamily
CEQ48_RS04100	COG3240	lipase activity
CEQ48_RS04110	COG0840	transmembrane signaling receptor activity
CEQ48_RS04135	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CEQ48_RS04140	COG4605	iron ion homeostasis
CEQ48_RS04145	COG4604	ABC transporter, ATP-binding protein
CEQ48_RS04150	COG2207	Transcriptional regulator
CEQ48_RS04170	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CEQ48_RS04190	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CEQ48_RS04205	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CEQ48_RS04210	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEQ48_RS04210	COG1263	PTS System
CEQ48_RS04220	COG2149	membrane
CEQ48_RS04235	COG3623	hexulose-6-phosphate isomerase
CEQ48_RS04240	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
CEQ48_RS04245	COG0561	phosphatase activity
CEQ48_RS04290	COG0745	RESPONSE REGULATOR receiver
CEQ48_RS04295	COG5002	protein histidine kinase activity
CEQ48_RS04305	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CEQ48_RS04315	COG3397	chitin binding
CEQ48_RS04320	COG3046	protein related to deoxyribodipyrimidine photolyase
CEQ48_RS04330	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CEQ48_RS04345	COG1028	Short-chain dehydrogenase reductase Sdr
CEQ48_RS04380	COG2986	histidine ammonia-lyase
CEQ48_RS04385	COG1216	Glycosyl transferase, family 2
CEQ48_RS04405	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CEQ48_RS04410	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CEQ48_RS04445	COG0513	Belongs to the DEAD box helicase family
CEQ48_RS04455	COG1368	sulfuric ester hydrolase activity
CEQ48_RS04460	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CEQ48_RS04475	COG0546	phosphoglycolate phosphatase activity
CEQ48_RS04495	COG0484	heat shock protein binding
CEQ48_RS04505	COG1716	ATPase activity
CEQ48_RS04505	COG5001	Diguanylate cyclase
CEQ48_RS04510	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CEQ48_RS04520	COG4181	ATPase activity
CEQ48_RS04525	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CEQ48_RS04540	COG1984	allophanate hydrolase subunit 2
CEQ48_RS04545	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CEQ48_RS04550	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CEQ48_RS04555	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CEQ48_RS04565	COG0814	amino acid
CEQ48_RS04575	COG0513	Belongs to the DEAD box helicase family
CEQ48_RS04580	COG1309	transcriptional regulator
CEQ48_RS04590	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CEQ48_RS04595	COG0494	nUDIX hydrolase
CEQ48_RS04605	COG2425	protein containing a von Willebrand factor type A (vWA) domain
CEQ48_RS04615	COG1126	abc transporter atp-binding protein
CEQ48_RS04620	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CEQ48_RS04625	COG4215	(ABC) transporter
CEQ48_RS04630	COG4160	amino acid transport
CEQ48_RS04660	COG3118	belongs to the thioredoxin family
CEQ48_RS04665	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CEQ48_RS04670	COG0247	lactate metabolic process
CEQ48_RS04675	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
CEQ48_RS04680	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CEQ48_RS04685	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CEQ48_RS04705	COG2926	Belongs to the UPF0265 family
CEQ48_RS04715	COG3132	Protein of unknown function, DUF480
CEQ48_RS04720	COG2827	Endonuclease containing a URI domain
CEQ48_RS04730	COG1879	ABC-type sugar transport system periplasmic component
CEQ48_RS04735	COG0784	Response regulator, receiver
CEQ48_RS04735	COG5002	protein histidine kinase activity
CEQ48_RS04760	COG1492	cobalamin metabolic process
CEQ48_RS04765	COG0725	ABC transporter, periplasmic molybdate-binding protein
CEQ48_RS04770	COG4149	molybdate abc transporter
CEQ48_RS04775	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CEQ48_RS04805	COG1289	transmembrane transporter activity
CEQ48_RS04810	COG0210	DNA helicase
CEQ48_RS04825	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CEQ48_RS04835	COG1335	isochorismatase
CEQ48_RS04840	COG1803	Methylglyoxal synthase
CEQ48_RS04845	COG1879	ABC-type sugar transport system periplasmic component
CEQ48_RS04850	COG2205	protein histidine kinase activity
CEQ48_RS04850	COG2198	Histidine kinase
CEQ48_RS04850	COG0784	Response regulator, receiver
CEQ48_RS04855	COG0469	pyruvate kinase activity
CEQ48_RS04860	COG2271	Major facilitator Superfamily
CEQ48_RS04870	COG4191	Histidine kinase
CEQ48_RS04895	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CEQ48_RS04925	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CEQ48_RS04935	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CEQ48_RS04940	COG1447	Phosphotransferase system cellobiose-specific component IIA
CEQ48_RS04960	COG0183	Belongs to the thiolase family
CEQ48_RS04970	COG3243	poly(R)-hydroxyalkanoic acid synthase
CEQ48_RS04975	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CEQ48_RS04995	COG0243	molybdopterin cofactor binding
CEQ48_RS05005	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CEQ48_RS05010	COG3850	Histidine kinase
CEQ48_RS05015	COG2197	response regulator
CEQ48_RS05020	COG1760	l-serine dehydratase
CEQ48_RS05025	COG3069	C4-dicarboxylate transmembrane transporter activity
CEQ48_RS05030	COG0840	transmembrane signaling receptor activity
CEQ48_RS05035	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CEQ48_RS05040	COG0545	Peptidyl-prolyl cis-trans isomerase
CEQ48_RS05055	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CEQ48_RS05065	COG1609	Transcriptional regulator
CEQ48_RS05070	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEQ48_RS05070	COG1263	PTS System
CEQ48_RS05130	COG2197	response regulator
CEQ48_RS05135	COG3850	Histidine kinase
CEQ48_RS05140	COG2223	nitrite transmembrane transporter activity
CEQ48_RS05145	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CEQ48_RS05150	COG1140	nitrate reductase beta subunit
CEQ48_RS05155	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CEQ48_RS05160	COG2181	nitrate reductase activity
CEQ48_RS05195	COG1328	CTP reductase activity
CEQ48_RS05200	COG0602	queuosine metabolic process
CEQ48_RS05210	COG0189	ligase activity
CEQ48_RS05210	COG4067	protein conserved in archaea
CEQ48_RS05215	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CEQ48_RS05215	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CEQ48_RS05215	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CEQ48_RS05220	COG1105	Belongs to the carbohydrate kinase PfkB family
CEQ48_RS05225	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEQ48_RS05225	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEQ48_RS05230	COG1609	Transcriptional regulator
CEQ48_RS05235	COG0420	3'-5' exonuclease activity
CEQ48_RS05240	COG0419	ATPase involved in DNA repair
CEQ48_RS05245	COG2205	protein histidine kinase activity
CEQ48_RS05245	COG0784	Response regulator, receiver
CEQ48_RS05250	COG0156	8-amino-7-oxononanoate synthase activity
CEQ48_RS05260	COG0038	chloride channel
CEQ48_RS05280	COG2200	EAL domain
CEQ48_RS05290	COG3038	cytochrome b561
CEQ48_RS05300	COG2116	formate transmembrane transporter activity
CEQ48_RS05305	COG0583	DNA-binding transcription factor activity
CEQ48_RS05315	COG3593	DNA synthesis involved in DNA repair
CEQ48_RS05320	COG0737	Belongs to the 5'-nucleotidase family
CEQ48_RS05325	COG0861	Integral membrane protein TerC family
CEQ48_RS05335	COG2824	Alkylphosphonate utilization operon protein PhnA
CEQ48_RS05370	COG2199	diguanylate cyclase activity
CEQ48_RS05390	COG3706	GGDEF domain
CEQ48_RS05405	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CEQ48_RS05410	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CEQ48_RS05420	COG0745	RESPONSE REGULATOR receiver
CEQ48_RS05435	COG3140	Belongs to the UPF0181 family
CEQ48_RS05475	COG1172	Belongs to the binding-protein-dependent transport system permease family
CEQ48_RS05480	COG1472	Belongs to the glycosyl hydrolase 3 family
CEQ48_RS05485	COG2199	diguanylate cyclase activity
CEQ48_RS05505	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CEQ48_RS05510	COG1758	RNA polymerase activity
CEQ48_RS05515	COG0194	GDP metabolic process
CEQ48_RS05520	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CEQ48_RS05525	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CEQ48_RS05545	COG4232	protein-disulfide reductase activity
CEQ48_RS05550	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CEQ48_RS05555	COG1027	Aspartate ammonia-lyase
CEQ48_RS05560	COG3706	GGDEF domain
CEQ48_RS05565	COG3030	protein affecting phage T7 exclusion by the F plasmid
CEQ48_RS05570	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CEQ48_RS05580	COG2205	protein histidine kinase activity
CEQ48_RS05585	COG0745	RESPONSE REGULATOR receiver
CEQ48_RS05595	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CEQ48_RS05600	COG0205	6-phosphofructokinase activity
CEQ48_RS05605	COG1494	fructose-1,6-bisphosphatase
CEQ48_RS05610	COG3074	FtsZ-dependent cytokinesis
CEQ48_RS05615	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CEQ48_RS05620	COG0460	homoserine dehydrogenase
CEQ48_RS05620	COG0527	aspartate kinase activity
CEQ48_RS05625	COG0626	cystathionine gamma-synthase activity
CEQ48_RS05630	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
CEQ48_RS05635	COG0281	malic enzyme
CEQ48_RS05640	COG0254	rRNA binding
CEQ48_RS05645	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CEQ48_RS05650	COG1609	Transcriptional regulator
CEQ48_RS05655	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CEQ48_RS05660	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CEQ48_RS05665	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CEQ48_RS05670	COG1575	Belongs to the MenA family. Type 1 subfamily
CEQ48_RS05675	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CEQ48_RS05680	COG0534	Mate efflux family protein
CEQ48_RS05685	COG0149	triose-phosphate isomerase activity
CEQ48_RS05710	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CEQ48_RS05715	COG0459	protein refolding
CEQ48_RS05725	COG1509	lysine 2,3-aminomutase activity
CEQ48_RS05730	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CEQ48_RS05740	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
CEQ48_RS05745	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CEQ48_RS05750	COG1053	succinate dehydrogenase
CEQ48_RS05755	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
CEQ48_RS05760	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CEQ48_RS05765	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
CEQ48_RS05770	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CEQ48_RS05775	COG1045	serine acetyltransferase
CEQ48_RS05785	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CEQ48_RS05790	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CEQ48_RS05795	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CEQ48_RS05800	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CEQ48_RS05805	COG0137	argininosuccinate synthase activity
CEQ48_RS05815	COG0165	Argininosuccinate lyase
CEQ48_RS05825	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CEQ48_RS05830	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CEQ48_RS05830	COG0678	peroxiredoxin activity
CEQ48_RS05840	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CEQ48_RS05870	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CEQ48_RS05875	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CEQ48_RS05885	COG0338	D12 class N6 adenine-specific DNA methyltransferase
CEQ48_RS05890	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CEQ48_RS05895	COG0546	phosphoglycolate phosphatase activity
CEQ48_RS05900	COG0180	Tryptophanyl-tRNA synthetase
CEQ48_RS05920	COG0446	pyridine nucleotide-disulphide oxidoreductase
CEQ48_RS05930	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CEQ48_RS05955	COG3954	Phosphoribulokinase
CEQ48_RS05965	COG0429	hydrolase of the alpha beta-hydrolase fold
CEQ48_RS05975	COG0488	(ABC) transporter
CEQ48_RS05980	COG2249	NAD(P)H dehydrogenase (quinone) activity
CEQ48_RS05995	COG1047	Peptidyl-prolyl cis-trans
CEQ48_RS06005	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CEQ48_RS06015	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CEQ48_RS06020	COG3083	sulfuric ester hydrolase activity
CEQ48_RS06025	COG0557	exoribonuclease II activity
CEQ48_RS06030	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CEQ48_RS06035	COG0051	transcription antitermination factor activity, RNA binding
CEQ48_RS06040	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CEQ48_RS06045	COG0088	Forms part of the polypeptide exit tunnel
CEQ48_RS06050	COG0089	rRNA binding
CEQ48_RS06055	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CEQ48_RS06060	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CEQ48_RS06065	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CEQ48_RS06070	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CEQ48_RS06075	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CEQ48_RS06080	COG0255	Belongs to the universal ribosomal protein uL29 family
CEQ48_RS06085	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CEQ48_RS06090	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CEQ48_RS06095	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CEQ48_RS06100	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CEQ48_RS06105	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CEQ48_RS06110	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CEQ48_RS06115	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CEQ48_RS06120	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CEQ48_RS06125	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CEQ48_RS06130	COG1841	ribosomal large subunit assembly
CEQ48_RS06140	COG0201	protein transport
CEQ48_RS06145	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CEQ48_RS06150	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CEQ48_RS06155	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CEQ48_RS06160	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CEQ48_RS06165	COG0202	RNA polymerase activity
CEQ48_RS06170	COG0203	ribosomal protein L17
CEQ48_RS06180	COG0545	Peptidyl-prolyl cis-trans isomerase
CEQ48_RS06185	COG3061	Opacity-associated protein A
CEQ48_RS06185	COG3266	domain, Protein
CEQ48_RS06190	COG0697	spore germination
CEQ48_RS06195	COG2153	protein acetylation
CEQ48_RS06200	COG0513	Belongs to the DEAD box helicase family
CEQ48_RS06210	COG0737	Belongs to the 5'-nucleotidase family
CEQ48_RS06215	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CEQ48_RS06215	COG1648	precorrin-2 dehydrogenase activity
CEQ48_RS06220	COG0175	sulfate reduction
CEQ48_RS06225	COG2895	sulfate adenylyltransferase (ATP) activity
CEQ48_RS06230	COG0529	Catalyzes the synthesis of activated sulfate
CEQ48_RS06250	COG0577	efflux transmembrane transporter activity
CEQ48_RS06250	COG1136	(ABC) transporter
CEQ48_RS06265	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
CEQ48_RS06270	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CEQ48_RS06275	COG0729	surface antigen
CEQ48_RS06285	COG2105	PFAM AIG2 family protein
CEQ48_RS06290	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CEQ48_RS06295	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CEQ48_RS06305	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CEQ48_RS06310	COG0163	prenyltransferase activity
CEQ48_RS06320	COG1178	ABC-type Fe3 transport system permease component
CEQ48_RS06325	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
CEQ48_RS06330	COG3028	Belongs to the UPF0307 family
CEQ48_RS06335	COG0312	modulator of DNA gyrase
CEQ48_RS06340	COG2239	Acts as a magnesium transporter
CEQ48_RS06345	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEQ48_RS06350	COG1660	Displays ATPase and GTPase activities
CEQ48_RS06355	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEQ48_RS06360	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CEQ48_RS06370	COG1137	ATPase activity
CEQ48_RS06375	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CEQ48_RS06390	COG0517	IMP dehydrogenase activity
CEQ48_RS06390	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CEQ48_RS06405	COG1127	ABC transporter
CEQ48_RS06410	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CEQ48_RS06415	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CEQ48_RS06420	COG2854	intermembrane phospholipid transfer
CEQ48_RS06430	COG5007	Belongs to the BolA IbaG family
CEQ48_RS06435	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CEQ48_RS06445	COG0251	oxidation-reduction process
CEQ48_RS06455	COG0540	Belongs to the ATCase OTCase family
CEQ48_RS06465	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CEQ48_RS06475	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CEQ48_RS06480	COG0564	pseudouridine synthase activity
CEQ48_RS06485	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CEQ48_RS06490	COG4269	membrane
CEQ48_RS06500	COG0525	valine-tRNA ligase activity
CEQ48_RS06505	COG2927	DNA polymerase III (CHI subunit)
CEQ48_RS06510	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CEQ48_RS06515	COG0795	lipopolysaccharide-transporting ATPase activity
CEQ48_RS06520	COG0795	lipopolysaccharide-transporting ATPase activity
CEQ48_RS06535	COG3437	response regulator, receiver
CEQ48_RS06575	COG0066	3-isopropylmalate dehydratase activity
CEQ48_RS06580	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CEQ48_RS06585	COG0473	3-isopropylmalate dehydrogenase activity
CEQ48_RS06610	COG0583	DNA-binding transcription factor activity
CEQ48_RS06615	COG1022	Amp-dependent synthetase and ligase
CEQ48_RS06625	COG0440	acetolactate synthase activity
CEQ48_RS06635	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CEQ48_RS06640	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CEQ48_RS06645	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CEQ48_RS06655	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
CEQ48_RS06660	COG3079	Belongs to the UPF0149 family
CEQ48_RS06665	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CEQ48_RS06670	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CEQ48_RS06685	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CEQ48_RS06695	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CEQ48_RS06705	COG1595	DNA-templated transcription, initiation
CEQ48_RS06720	COG3086	response to oxidative stress
CEQ48_RS06725	COG0481	GTPase activity
CEQ48_RS06735	COG0571	ribonuclease III activity
CEQ48_RS06740	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CEQ48_RS06745	COG1381	Involved in DNA repair and RecF pathway recombination
CEQ48_RS06750	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CEQ48_RS06755	COG0736	holo-[acyl-carrier-protein] synthase activity
CEQ48_RS06775	COG3850	Histidine kinase
CEQ48_RS06775	COG3437	response regulator, receiver
CEQ48_RS06775	COG2205	protein histidine kinase activity
CEQ48_RS06775	COG4999	Histidine kinase
CEQ48_RS06785	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CEQ48_RS06790	COG3956	TIGRFAM MazG family protein
CEQ48_RS06795	COG0504	CTP synthase activity
CEQ48_RS06800	COG0148	phosphopyruvate hydratase activity
CEQ48_RS06805	COG0617	tRNA 3'-terminal CCA addition
CEQ48_RS06810	COG3267	Type II secretory pathway component ExeA
CEQ48_RS06810	COG3409	Peptidoglycan-binding domain 1 protein
CEQ48_RS06820	COG4991	sh3 domain protein
CEQ48_RS06825	COG0306	phosphate transporter
CEQ48_RS06830	COG1392	Phosphate transport regulator
CEQ48_RS06835	COG3025	triphosphatase activity
CEQ48_RS06845	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CEQ48_RS06850	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CEQ48_RS06850	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CEQ48_RS06855	COG1538	Outer membrane efflux protein
CEQ48_RS06860	COG0494	nUDIX hydrolase
CEQ48_RS06865	COG3151	Protein conserved in bacteria
CEQ48_RS06875	COG3150	esterase
CEQ48_RS06880	COG0187	DNA topoisomerase II activity
CEQ48_RS06885	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CEQ48_RS06895	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
CEQ48_RS06900	COG0237	dephospho-CoA kinase activity
CEQ48_RS06910	COG1459	type II secretion system
CEQ48_RS06915	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CEQ48_RS06935	COG0716	FMN binding
CEQ48_RS06940	COG4974	Belongs to the 'phage' integrase family
CEQ48_RS06945	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CEQ48_RS06950	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CEQ48_RS06960	COG2186	Transcriptional regulator
CEQ48_RS06965	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CEQ48_RS06970	COG0508	dehydrogenase complex catalyzes the overall conversion of
CEQ48_RS06975	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CEQ48_RS06990	COG3116	cell division
CEQ48_RS06995	COG0768	penicillin binding
CEQ48_RS07000	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CEQ48_RS07005	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CEQ48_RS07015	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CEQ48_RS07020	COG0772	Belongs to the SEDS family
CEQ48_RS07025	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CEQ48_RS07030	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CEQ48_RS07035	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CEQ48_RS07040	COG0849	cell division
CEQ48_RS07045	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CEQ48_RS07050	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CEQ48_RS07060	COG0653	protein targeting
CEQ48_RS07065	COG0494	nUDIX hydrolase
CEQ48_RS07070	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CEQ48_RS07080	COG0505	Belongs to the CarA family
CEQ48_RS07085	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CEQ48_RS07105	COG0730	response to heat
CEQ48_RS07110	COG0583	DNA-binding transcription factor activity
CEQ48_RS07115	COG2860	membrane
CEQ48_RS07130	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CEQ48_RS07140	COG0493	'glutamate synthase
CEQ48_RS07145	COG0070	glutamate synthase
CEQ48_RS07145	COG0069	glutamate synthase activity
CEQ48_RS07145	COG0067	glutamate synthase
CEQ48_RS07155	COG0070	glutamate synthase
CEQ48_RS07155	COG0067	glutamate synthase
CEQ48_RS07155	COG0069	glutamate synthase activity
CEQ48_RS07160	COG1242	4 iron, 4 sulfur cluster binding
CEQ48_RS07165	COG5001	Diguanylate cyclase
CEQ48_RS07165	COG4251	negative regulation of phosphorylation
CEQ48_RS07165	COG3706	GGDEF domain
CEQ48_RS07165	COG2203	Gaf domain
CEQ48_RS07170	COG5002	protein histidine kinase activity
CEQ48_RS07170	COG0784	Response regulator, receiver
CEQ48_RS07170	COG2198	Histidine kinase
CEQ48_RS07175	COG0745	RESPONSE REGULATOR receiver
CEQ48_RS07185	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CEQ48_RS07205	COG0083	homoserine kinase activity
CEQ48_RS07210	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CEQ48_RS07215	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
CEQ48_RS07220	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CEQ48_RS07225	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CEQ48_RS07240	COG1115	amino acid carrier protein
CEQ48_RS07245	COG3022	response to hydroperoxide
CEQ48_RS07250	COG0084	hydrolase, TatD family'
CEQ48_RS07255	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CEQ48_RS07265	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CEQ48_RS07270	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
CEQ48_RS07275	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CEQ48_RS07280	COG0813	purine-nucleoside phosphorylase activity
CEQ48_RS07290	COG0560	Phosphoserine phosphatase
CEQ48_RS07300	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CEQ48_RS07305	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CEQ48_RS07310	COG1022	Amp-dependent synthetase and ligase
CEQ48_RS07325	COG3250	beta-galactosidase activity
CEQ48_RS07330	COG1609	Transcriptional regulator
CEQ48_RS07335	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CEQ48_RS07350	COG0189	ligase activity
CEQ48_RS07350	COG0569	domain protein
CEQ48_RS07355	COG0456	acetyltransferase
CEQ48_RS07365	COG2171	N-acyltransferase activity
CEQ48_RS07375	COG3141	response to X-ray
CEQ48_RS07390	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CEQ48_RS07395	COG1074	ATP-dependent DNA helicase activity
CEQ48_RS07400	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CEQ48_RS07415	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CEQ48_RS07415	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CEQ48_RS07425	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CEQ48_RS07430	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CEQ48_RS07435	COG2166	iron-sulfur cluster assembly
CEQ48_RS07440	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CEQ48_RS07445	COG0693	protein deglycase activity
CEQ48_RS07450	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CEQ48_RS07455	COG3248	Nucleoside-binding outer membrane protein
CEQ48_RS07465	COG1595	DNA-templated transcription, initiation
CEQ48_RS07475	COG2211	Major facilitator Superfamily
CEQ48_RS07480	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CEQ48_RS07490	COG2813	Specifically methylates the guanine in position
CEQ48_RS07495	COG0271	Belongs to the BolA IbaG family
CEQ48_RS07500	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CEQ48_RS07505	COG1805	sodium ion transport
CEQ48_RS07510	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CEQ48_RS07515	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CEQ48_RS07520	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CEQ48_RS07525	COG2871	sodium ion transport
CEQ48_RS07530	COG1477	protein flavinylation
CEQ48_RS07550	COG3706	GGDEF domain
CEQ48_RS07555	COG0733	neurotransmitter:sodium symporter activity
CEQ48_RS07565	COG0189	ligase activity
CEQ48_RS07570	COG4067	protein conserved in archaea
CEQ48_RS07570	COG0189	ligase activity
CEQ48_RS07575	COG2195	Cleaves the N-terminal amino acid of tripeptides
CEQ48_RS07580	COG2252	PERMEase
CEQ48_RS07585	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
CEQ48_RS07590	COG1073	alpha beta
CEQ48_RS07600	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CEQ48_RS07605	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CEQ48_RS07610	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CEQ48_RS07615	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CEQ48_RS07615	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CEQ48_RS07630	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CEQ48_RS07635	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CEQ48_RS07640	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CEQ48_RS07645	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CEQ48_RS07655	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CEQ48_RS07660	COG0024	Methionine aminopeptidase
CEQ48_RS07665	COG0052	Belongs to the universal ribosomal protein uS2 family
CEQ48_RS07670	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CEQ48_RS07675	COG0528	UMP kinase activity
CEQ48_RS07680	COG0233	cytoplasmic translational termination
CEQ48_RS07685	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CEQ48_RS07690	COG0575	Belongs to the CDS family
CEQ48_RS07695	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CEQ48_RS07710	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
CEQ48_RS07715	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CEQ48_RS07720	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CEQ48_RS07725	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CEQ48_RS07730	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CEQ48_RS07735	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CEQ48_RS07740	COG0587	DNA-directed DNA polymerase activity
CEQ48_RS07745	COG0825	malonyl-CoA metabolic process
CEQ48_RS07750	COG0037	tRNA processing
CEQ48_RS07760	COG0347	Belongs to the P(II) protein family
CEQ48_RS07765	COG3021	interspecies interaction between organisms
CEQ48_RS07770	COG1388	LysM domain
CEQ48_RS07770	COG0741	lytic transglycosylase activity
CEQ48_RS07775	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CEQ48_RS07780	COG2226	methyltransferase
CEQ48_RS07785	COG0328	RNA-DNA hybrid ribonuclease activity
CEQ48_RS07800	COG1960	acyl-CoA dehydrogenase activity
CEQ48_RS07805	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CEQ48_RS07810	COG0121	glutamine amidotransferase
CEQ48_RS07815	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CEQ48_RS07820	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CEQ48_RS07825	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CEQ48_RS07830	COG1187	pseudouridine synthase activity
CEQ48_RS07835	COG2840	Smr protein MutS2
CEQ48_RS07870	COG2217	Heavy metal translocating P-type atpase
CEQ48_RS07870	COG2608	mercury ion transmembrane transporter activity
CEQ48_RS07875	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CEQ48_RS07895	COG2375	cellular response to nickel ion
CEQ48_RS07935	COG0835	chemotaxis
CEQ48_RS07935	COG0784	Response regulator, receiver
CEQ48_RS07940	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CEQ48_RS07945	COG1815	bacterial-type flagellum-dependent cell motility
CEQ48_RS07960	COG1749	Flagellar hook protein flgE
CEQ48_RS07965	COG4787	bacterial-type flagellum-dependent cell motility
CEQ48_RS07975	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
CEQ48_RS07980	COG1706	bacterial-type flagellum-dependent cell motility
CEQ48_RS07985	COG1705	Flagellar rod assembly protein muramidase FlgJ
CEQ48_RS07985	COG3951	Flagellar rod assembly protein muramidase FlgJ
CEQ48_RS08000	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CEQ48_RS08005	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CEQ48_RS08090	COG0012	GTP binding
CEQ48_RS08095	COG0193	aminoacyl-tRNA hydrolase activity
CEQ48_RS08100	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CEQ48_RS08110	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
CEQ48_RS08115	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CEQ48_RS08120	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CEQ48_RS08125	COG2890	protein-(glutamine-N5) methyltransferase activity
CEQ48_RS08135	COG2912	Transglutaminase-like superfamily
CEQ48_RS08140	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CEQ48_RS08145	COG0737	Belongs to the 5'-nucleotidase family
CEQ48_RS08150	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CEQ48_RS08155	COG2233	PERMEase
CEQ48_RS08175	COG1393	Belongs to the ArsC family
CEQ48_RS08180	COG4783	chaperone-mediated protein folding
CEQ48_RS08200	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CEQ48_RS08215	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CEQ48_RS08225	COG1876	peptidase activity
CEQ48_RS08235	COG1393	Belongs to the ArsC family
CEQ48_RS08255	COG2837	iron assimilation
CEQ48_RS08260	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CEQ48_RS08265	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CEQ48_RS08270	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CEQ48_RS08275	COG1334	flagellar protein FlaG
CEQ48_RS08280	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CEQ48_RS08290	COG1516	flagellar protein fliS
CEQ48_RS08310	COG1677	Flagellar hook-basal body complex protein FliE
CEQ48_RS08320	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CEQ48_RS08325	COG1317	bacterial-type flagellum organization
CEQ48_RS08350	COG1580	Controls the rotational direction of flagella during chemotaxis
CEQ48_RS08375	COG1987	bacterial-type flagellum assembly
CEQ48_RS08380	COG1684	flagellar biosynthetic protein fliR
CEQ48_RS08390	COG2840	Smr protein MutS2
CEQ48_RS08395	COG2890	protein-(glutamine-N5) methyltransferase activity
CEQ48_RS08400	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CEQ48_RS08405	COG2860	membrane
CEQ48_RS08410	COG3101	peptidyl-lysine hydroxylation
CEQ48_RS08420	COG0431	NADPH-dependent FMN reductase
CEQ48_RS08425	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CEQ48_RS08425	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CEQ48_RS08430	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CEQ48_RS08435	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CEQ48_RS08440	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CEQ48_RS08445	COG0735	belongs to the Fur family
CEQ48_RS08455	COG0583	DNA-binding transcription factor activity
CEQ48_RS08465	COG1346	cytolysis
CEQ48_RS08480	COG0596	Alpha beta hydrolase
CEQ48_RS08485	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
CEQ48_RS08490	COG0033	Phosphoglucomutase
CEQ48_RS08500	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CEQ48_RS08505	COG0372	Belongs to the citrate synthase family
CEQ48_RS08510	COG2009	succinate dehydrogenase
CEQ48_RS08515	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CEQ48_RS08520	COG1053	succinate dehydrogenase
CEQ48_RS08530	COG0567	Dehydrogenase, E1 component
CEQ48_RS08535	COG0508	dehydrogenase complex catalyzes the overall conversion of
CEQ48_RS08540	COG0045	succinate-CoA ligase (ADP-forming) activity
CEQ48_RS08550	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CEQ48_RS08555	COG1121	(ABC) transporter
CEQ48_RS08560	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
CEQ48_RS08565	COG4977	sequence-specific DNA binding
CEQ48_RS08570	COG1918	ferrous iron import across plasma membrane
CEQ48_RS08590	COG0018	arginyl-trna synthetase
CEQ48_RS08600	COG1025	Belongs to the peptidase M16 family
CEQ48_RS08605	COG2062	phosphohistidine phosphatase, SixA
CEQ48_RS08635	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
CEQ48_RS08640	COG0643	Histidine kinase
CEQ48_RS08640	COG0784	Response regulator, receiver
CEQ48_RS08640	COG2198	Histidine kinase
CEQ48_RS08645	COG2201	protein-glutamate methylesterase activity
CEQ48_RS08650	COG1192	Involved in chromosome partitioning
CEQ48_RS08660	COG0835	chemotaxis
CEQ48_RS08670	COG4133	protoheme IX ABC transporter activity
CEQ48_RS08675	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CEQ48_RS08680	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CEQ48_RS08690	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
CEQ48_RS08695	COG1138	Cytochrome C-type biogenesis protein
CEQ48_RS08700	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CEQ48_RS08715	COG2853	Lipoprotein
CEQ48_RS08735	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CEQ48_RS08740	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CEQ48_RS08745	COG0123	including yeast histone deacetylase and acetoin utilization protein
CEQ48_RS08760	COG3083	sulfuric ester hydrolase activity
CEQ48_RS08765	COG3082	Protein of unknown function (DUF1414)
CEQ48_RS08770	COG3081	Nucleoid-associated protein
CEQ48_RS08780	COG1757	Na H antiporter
CEQ48_RS08785	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CEQ48_RS08790	COG2095	MarC family integral membrane protein
CEQ48_RS08795	COG1454	alcohol dehydrogenase
CEQ48_RS08795	COG1012	belongs to the aldehyde dehydrogenase family
CEQ48_RS08810	COG0659	secondary active sulfate transmembrane transporter activity
CEQ48_RS08815	COG1530	ribonuclease E activity
CEQ48_RS08830	COG0564	pseudouridine synthase activity
CEQ48_RS08835	COG0424	maF-like protein
CEQ48_RS08840	COG1399	metal-binding, possibly nucleic acid-binding protein
CEQ48_RS08845	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CEQ48_RS08850	COG0416	fatty acid biosynthetic process
CEQ48_RS08855	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CEQ48_RS08865	COG1028	Short-chain dehydrogenase reductase Sdr
CEQ48_RS08870	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CEQ48_RS08875	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CEQ48_RS08880	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CEQ48_RS08885	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CEQ48_RS08900	COG0084	hydrolase, TatD family'
CEQ48_RS08905	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEQ48_RS08905	COG1263	PTS System
CEQ48_RS08915	COG0733	neurotransmitter:sodium symporter activity
CEQ48_RS08925	COG4667	esterase of the alpha-beta hydrolase superfamily
CEQ48_RS08930	COG0469	pyruvate kinase activity
CEQ48_RS08935	COG1940	carbohydrate kinase activity
CEQ48_RS08940	COG0835	chemotaxis
CEQ48_RS08940	COG0784	Response regulator, receiver
CEQ48_RS08970	COG2226	methyltransferase
CEQ48_RS08985	COG0676	glucose-6-phosphate 1-epimerase activity
CEQ48_RS08990	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CEQ48_RS08995	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CEQ48_RS09005	COG3139	Protein of unknown function (DUF1315)
CEQ48_RS09010	COG0252	asparaginase activity
CEQ48_RS09015	COG0616	signal peptide processing
CEQ48_RS09020	COG0446	pyridine nucleotide-disulphide oxidoreductase
CEQ48_RS09020	COG1902	pentaerythritol trinitrate reductase activity
CEQ48_RS09025	COG0788	formyltetrahydrofolate deformylase activity
CEQ48_RS09035	COG1199	ATP-dependent helicase activity
CEQ48_RS09040	COG1214	PFAM Peptidase M22, glycoprotease
CEQ48_RS09055	COG0596	Alpha beta hydrolase
CEQ48_RS09060	COG0318	PFAM AMP-dependent synthetase and ligase
CEQ48_RS09065	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CEQ48_RS09085	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CEQ48_RS09090	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
CEQ48_RS09095	COG0436	Aminotransferase
CEQ48_RS09100	COG1169	isochorismate synthase
CEQ48_RS09105	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CEQ48_RS09110	COG0596	Alpha beta hydrolase
CEQ48_RS09130	COG3135	benzoate transporter
CEQ48_RS09135	COG1396	sequence-specific DNA binding
CEQ48_RS09165	COG3015	lipoprotein NlpE involved in copper resistance
CEQ48_RS09170	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CEQ48_RS09175	COG2894	cell division
CEQ48_RS09180	COG0850	regulation of cytokinetic process
CEQ48_RS09185	COG3100	YcgL domain-containing protein
CEQ48_RS09190	COG2951	lytic endotransglycosylase activity
CEQ48_RS09205	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CEQ48_RS09210	COG3469	chitinase activity
CEQ48_RS09210	COG3325	Belongs to the glycosyl hydrolase 18 family
CEQ48_RS09220	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CEQ48_RS09250	COG4264	IucA IucC family
CEQ48_RS09260	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CEQ48_RS09265	COG1120	ATPase activity
CEQ48_RS09300	COG0671	phosphoesterase, PA-phosphatase related
CEQ48_RS09315	COG4589	Belongs to the CDS family
CEQ48_RS09340	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CEQ48_RS09345	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CEQ48_RS09350	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CEQ48_RS09355	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CEQ48_RS09365	COG4191	Histidine kinase
CEQ48_RS09375	COG0544	peptidyl-prolyl cis-trans isomerase activity
CEQ48_RS09385	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CEQ48_RS09390	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CEQ48_RS09395	COG0776	regulation of translation
CEQ48_RS09400	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CEQ48_RS09405	COG1555	photosystem II stabilization
CEQ48_RS09410	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CEQ48_RS09415	COG0539	negative regulation of cytoplasmic translation
CEQ48_RS09420	COG0776	regulation of translation
CEQ48_RS09425	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
CEQ48_RS09430	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CEQ48_RS09440	COG4174	ABC transporter (Permease)
CEQ48_RS09445	COG4239	(ABC) transporter, permease
CEQ48_RS09450	COG0747	negative chemotaxis
CEQ48_RS09455	COG0444	Belongs to the ABC transporter superfamily
CEQ48_RS09460	COG4608	Belongs to the ABC transporter superfamily
CEQ48_RS09500	COG0583	DNA-binding transcription factor activity
CEQ48_RS09510	COG0686	Belongs to the AlaDH PNT family
CEQ48_RS09515	COG1522	sequence-specific DNA binding
CEQ48_RS09520	COG1674	ftsk spoiiie
CEQ48_RS09525	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CEQ48_RS09535	COG2186	Transcriptional regulator
CEQ48_RS09545	COG0840	transmembrane signaling receptor activity
CEQ48_RS09550	COG0537	adenosine 5'-monophosphoramidase activity
CEQ48_RS09575	COG3150	esterase
CEQ48_RS09580	COG1252	NADH dehydrogenase
CEQ48_RS09600	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CEQ48_RS09615	COG1136	(ABC) transporter
CEQ48_RS09620	COG4591	ABC-type transport system involved in lipoprotein release permease component
CEQ48_RS09630	COG2333	competence protein COMEC
CEQ48_RS09630	COG0658	competence protein
CEQ48_RS09635	COG1132	(ABC) transporter
CEQ48_RS09640	COG1663	tetraacyldisaccharide 4'-kinase activity
CEQ48_RS09645	COG2835	tetraacyldisaccharide 4'-kinase activity
CEQ48_RS09650	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CEQ48_RS09655	COG2719	SpoVR family
CEQ48_RS09660	COG2718	Belongs to the UPF0229 family
CEQ48_RS09665	COG2766	serine protein kinase
CEQ48_RS09670	COG3013	Belongs to the UPF0304 family
CEQ48_RS09680	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CEQ48_RS09685	COG0840	transmembrane signaling receptor activity
CEQ48_RS09695	COG1882	Formate acetyltransferase
CEQ48_RS09720	COG4160	amino acid transport
CEQ48_RS09725	COG0708	Exodeoxyribonuclease III
CEQ48_RS09740	COG3923	Primosomal replication protein n
CEQ48_RS09745	COG0730	response to heat
CEQ48_RS09750	COG1199	ATP-dependent helicase activity
CEQ48_RS09760	COG3012	SEC-C Motif Domain Protein
CEQ48_RS09765	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
CEQ48_RS09770	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CEQ48_RS09775	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CEQ48_RS09780	COG0215	cysteine-tRNA ligase activity
CEQ48_RS09785	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CEQ48_RS09790	COG0632	four-way junction helicase activity
CEQ48_RS09800	COG1271	oxidase subunit
CEQ48_RS09805	COG1294	oxidase, subunit
CEQ48_RS09810	COG4890	Cyd operon protein YbgT
CEQ48_RS09815	COG3790	cyd operon protein YbgE
CEQ48_RS09820	COG0824	Thioesterase
CEQ48_RS09825	COG0811	peptide transport
CEQ48_RS09840	COG0823	Involved in the tonB-independent uptake of proteins
CEQ48_RS09845	COG2885	chlorophyll binding
CEQ48_RS09855	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CEQ48_RS09865	COG5002	protein histidine kinase activity
CEQ48_RS09865	COG0784	Response regulator, receiver
CEQ48_RS09875	COG1012	belongs to the aldehyde dehydrogenase family
CEQ48_RS09880	COG3284	Transcriptional regulator
CEQ48_RS09885	COG4628	conserved protein (DUF2132)
CEQ48_RS09905	COG1940	carbohydrate kinase activity
CEQ48_RS09920	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CEQ48_RS09925	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CEQ48_RS09930	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CEQ48_RS09935	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CEQ48_RS09940	COG1737	Transcriptional regulator
CEQ48_RS09945	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
CEQ48_RS09950	COG2003	Belongs to the UPF0758 family
CEQ48_RS09990	COG0596	Alpha beta hydrolase
CEQ48_RS10000	COG3064	Membrane
CEQ48_RS10125	COG4789	Type iii secretion
CEQ48_RS10130	COG4792	protein secretion
CEQ48_RS10160	COG3710	Transcriptional regulator
CEQ48_RS10175	COG4790	Type iii secretion
CEQ48_RS10255	COG0582	viral genome integration into host DNA
CEQ48_RS10280	COG3069	C4-dicarboxylate transmembrane transporter activity
CEQ48_RS10285	COG2195	Cleaves the N-terminal amino acid of tripeptides
CEQ48_RS10295	COG2200	EAL domain
CEQ48_RS10300	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CEQ48_RS10305	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CEQ48_RS10315	COG3008	intermembrane lipid transfer
CEQ48_RS10315	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CEQ48_RS10320	COG2995	paraquat-inducible protein a
CEQ48_RS10325	COG0668	transmembrane transport
CEQ48_RS10335	COG1309	transcriptional regulator
CEQ48_RS10340	COG1012	belongs to the aldehyde dehydrogenase family
CEQ48_RS10365	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CEQ48_RS10375	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CEQ48_RS10385	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CEQ48_RS10405	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CEQ48_RS10410	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CEQ48_RS10415	COG0297	glycogen (starch) synthase activity
CEQ48_RS10440	COG3070	regulator of competence-specific genes
CEQ48_RS10445	COG1609	Transcriptional regulator
CEQ48_RS10455	COG3381	protein complex oligomerization
CEQ48_RS10460	COG0745	RESPONSE REGULATOR receiver
CEQ48_RS10465	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CEQ48_RS10470	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CEQ48_RS10475	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
CEQ48_RS10480	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
CEQ48_RS10500	COG1032	radical SAM domain protein
CEQ48_RS10510	COG0612	Peptidase, M16
CEQ48_RS10525	COG0583	DNA-binding transcription factor activity
CEQ48_RS10530	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CEQ48_RS10540	COG2350	Protein conserved in bacteria
CEQ48_RS10545	COG1607	acyl-coa hydrolase
CEQ48_RS10565	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CEQ48_RS10570	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CEQ48_RS10585	COG2116	formate transmembrane transporter activity
CEQ48_RS10600	COG4459	periplasmic nitrate reductase
CEQ48_RS10605	COG3005	denitrification pathway
CEQ48_RS10610	COG0243	molybdopterin cofactor binding
CEQ48_RS10625	COG1227	inorganic diphosphatase activity
CEQ48_RS10640	COG4172	Belongs to the ABC transporter superfamily
CEQ48_RS10655	COG4168	peptide transport system, permease
CEQ48_RS10665	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CEQ48_RS10670	COG1842	Phage shock protein A
CEQ48_RS10685	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CEQ48_RS10700	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CEQ48_RS10705	COG2818	Glycosylase
CEQ48_RS10710	COG0626	cystathionine gamma-synthase activity
CEQ48_RS10720	COG0733	neurotransmitter:sodium symporter activity
CEQ48_RS10735	COG0564	pseudouridine synthase activity
CEQ48_RS10740	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CEQ48_RS10745	COG4136	ATPase activity
CEQ48_RS10750	COG4135	transport system, permease component
CEQ48_RS10755	COG4134	Bacterial extracellular solute-binding protein
CEQ48_RS10765	COG3313	Fe-S protein
CEQ48_RS10775	COG0842	Transport permease protein
CEQ48_RS10780	COG1131	(ABC) transporter
CEQ48_RS10785	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CEQ48_RS10790	COG0814	amino acid
CEQ48_RS10800	COG2239	Acts as a magnesium transporter
CEQ48_RS10805	COG2205	protein histidine kinase activity
CEQ48_RS10805	COG0784	Response regulator, receiver
CEQ48_RS10820	COG4934	collagen metabolic process
CEQ48_RS10855	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CEQ48_RS10870	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CEQ48_RS10890	COG1061	Type III restriction enzyme res subunit
CEQ48_RS10895	COG1187	pseudouridine synthase activity
CEQ48_RS10900	COG2814	Major facilitator Superfamily
CEQ48_RS10910	COG0702	epimerase
CEQ48_RS10915	COG0534	Mate efflux family protein
CEQ48_RS10920	COG4181	ATPase activity
CEQ48_RS10925	COG0577	efflux transmembrane transporter activity
CEQ48_RS10935	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CEQ48_RS10950	COG1748	Saccharopine dehydrogenase
CEQ48_RS10965	COG1538	Outer membrane efflux protein
CEQ48_RS10995	COG0583	DNA-binding transcription factor activity
CEQ48_RS11005	COG1451	nucleotide metabolic process
CEQ48_RS11020	COG3063	Type IV pilus biogenesis stability protein PilW
CEQ48_RS11025	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
CEQ48_RS11045	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CEQ48_RS11060	COG3290	protein histidine kinase activity
CEQ48_RS11065	COG4565	transcriptional regulatory protein
CEQ48_RS11075	COG0835	chemotaxis
CEQ48_RS11075	COG0784	Response regulator, receiver
CEQ48_RS11110	COG1085	galactose-1-phosphate uridylyltransferase
CEQ48_RS11115	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CEQ48_RS11120	COG2017	converts alpha-aldose to the beta-anomer
CEQ48_RS11130	COG2199	diguanylate cyclase activity
CEQ48_RS11130	COG2200	EAL domain
CEQ48_RS11135	COG0753	catalase activity
CEQ48_RS11145	COG3097	Belongs to the UPF0267 family
CEQ48_RS11185	COG1271	oxidase subunit
CEQ48_RS11190	COG1294	oxidase, subunit
CEQ48_RS11220	COG2723	6-phospho-beta-galactosidase activity
CEQ48_RS11230	COG0251	oxidation-reduction process
CEQ48_RS11235	COG2731	YhcH YjgK YiaL family protein
CEQ48_RS11240	COG0584	glycerophosphoryl diester phosphodiesterase
CEQ48_RS11245	COG1349	DNA-binding transcription factor activity
CEQ48_RS11250	COG3842	ATPase activity
CEQ48_RS11255	COG0395	ABC-type sugar transport system, permease component
CEQ48_RS11260	COG1175	transmembrane transport
CEQ48_RS11275	COG0811	peptide transport
CEQ48_RS11280	COG0811	peptide transport
CEQ48_RS11285	COG0848	biopolymer transport protein
CEQ48_RS11290	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
CEQ48_RS11305	COG1793	dna ligase
CEQ48_RS11320	COG2801	Transposase and inactivated derivatives
CEQ48_RS11325	COG0534	Mate efflux family protein
CEQ48_RS11335	COG3001	Fructosamine kinase
CEQ48_RS11345	COG0791	NLP P60 protein
CEQ48_RS11350	COG0840	transmembrane signaling receptor activity
CEQ48_RS11365	COG1940	carbohydrate kinase activity
CEQ48_RS11375	COG0303	'Molybdopterin
CEQ48_RS11380	COG0746	molybdenum cofactor guanylyltransferase activity
CEQ48_RS11385	COG3842	ATPase activity
CEQ48_RS11390	COG4662	Binding-protein-dependent transport system inner membrane component
CEQ48_RS11400	COG2204	response regulator
CEQ48_RS11405	COG3852	Histidine kinase
CEQ48_RS11410	COG0488	(ABC) transporter
CEQ48_RS11425	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CEQ48_RS11460	COG0437	4 iron, 4 sulfur cluster binding
CEQ48_RS11475	COG0004	ammonium transporteR
CEQ48_RS11480	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CEQ48_RS11485	COG1666	GTP binding
CEQ48_RS11490	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CEQ48_RS11505	COG2996	Protein conserved in bacteria
CEQ48_RS11515	COG3008	intermembrane lipid transfer
CEQ48_RS11520	COG2995	paraquat-inducible protein a
CEQ48_RS11525	COG1132	(ABC) transporter
CEQ48_RS11530	COG1956	GAF domain-containing protein
CEQ48_RS11535	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
CEQ48_RS11550	COG0308	aminopeptidase N
CEQ48_RS11565	COG0167	dihydroorotate dehydrogenase activity
CEQ48_RS11580	COG0116	Belongs to the methyltransferase superfamily
CEQ48_RS11580	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CEQ48_RS11590	COG0488	(ABC) transporter
CEQ48_RS11605	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CEQ48_RS11610	COG1067	ATP-dependent peptidase activity
CEQ48_RS11615	COG3120	sequence-specific DNA binding
CEQ48_RS11630	COG3850	Histidine kinase
CEQ48_RS11630	COG2205	protein histidine kinase activity
CEQ48_RS11630	COG4999	Histidine kinase
CEQ48_RS11630	COG3437	response regulator, receiver
CEQ48_RS11645	COG3278	Belongs to the heme-copper respiratory oxidase family
CEQ48_RS11660	COG2010	Cytochrome c
CEQ48_RS11670	COG2217	Heavy metal translocating P-type atpase
CEQ48_RS11685	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CEQ48_RS11690	COG0589	response to stress
CEQ48_RS11695	COG0037	tRNA processing
CEQ48_RS11715	COG3842	ATPase activity
CEQ48_RS11725	COG1177	transmembrane transport
CEQ48_RS11735	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CEQ48_RS11750	COG1115	amino acid carrier protein
CEQ48_RS11755	COG1280	lysine exporter protein (LysE YggA)
CEQ48_RS11775	COG3501	Rhs element vgr protein
CEQ48_RS11785	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CEQ48_RS11790	COG0513	Belongs to the DEAD box helicase family
CEQ48_RS11800	COG0840	transmembrane signaling receptor activity
CEQ48_RS11810	COG0477	Major facilitator Superfamily
CEQ48_RS11815	COG0583	DNA-binding transcription factor activity
CEQ48_RS11825	COG0402	S-adenosylhomocysteine deaminase activity
CEQ48_RS11830	COG0095	Lipoate-protein ligase
CEQ48_RS11835	COG0443	Heat shock 70 kDa protein
CEQ48_RS11845	COG1643	Atp-dependent helicase
CEQ48_RS11885	COG0443	Heat shock 70 kDa protein
CEQ48_RS11890	COG3706	GGDEF domain
CEQ48_RS11920	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CEQ48_RS11925	COG0602	queuosine metabolic process
CEQ48_RS11930	COG0561	phosphatase activity
CEQ48_RS11940	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CEQ48_RS11945	COG4597	amino acid ABC transporter
CEQ48_RS11950	COG0765	amino acid transport
CEQ48_RS11955	COG1126	abc transporter atp-binding protein
CEQ48_RS11960	COG0670	Belongs to the BI1 family
CEQ48_RS11965	COG2920	part of a sulfur-relay system
CEQ48_RS11970	COG1254	Belongs to the acylphosphatase family
CEQ48_RS11975	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CEQ48_RS11980	COG3706	GGDEF domain
CEQ48_RS11995	COG4999	Histidine kinase
CEQ48_RS11995	COG2205	protein histidine kinase activity
CEQ48_RS11995	COG3437	response regulator, receiver
CEQ48_RS11995	COG3850	Histidine kinase
CEQ48_RS12000	COG3437	response regulator, receiver
CEQ48_RS12005	COG0625	glutathione transferase activity
CEQ48_RS12015	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
CEQ48_RS12025	COG2195	Cleaves the N-terminal amino acid of tripeptides
CEQ48_RS12055	COG0372	Belongs to the citrate synthase family
CEQ48_RS12060	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CEQ48_RS12070	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CEQ48_RS12105	COG1129	ABC transporter
CEQ48_RS12140	COG4191	Histidine kinase
CEQ48_RS12140	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CEQ48_RS12145	COG0471	metal ion transport
CEQ48_RS12155	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CEQ48_RS12180	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CEQ48_RS12190	COG3768	UPF0283 membrane protein
CEQ48_RS12195	COG3106	COG3106 Predicted ATPase
CEQ48_RS12210	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CEQ48_RS12215	COG0494	nUDIX hydrolase
CEQ48_RS12220	COG0814	amino acid
CEQ48_RS12225	COG1760	l-serine dehydratase
CEQ48_RS12230	COG0720	synthase
CEQ48_RS12235	COG0840	transmembrane signaling receptor activity
CEQ48_RS12240	COG0017	Asparaginyl-tRNA synthetase
CEQ48_RS12245	COG0351	phosphomethylpyrimidine kinase
CEQ48_RS12250	COG3437	response regulator, receiver
CEQ48_RS12250	COG2770	Histidine kinase
CEQ48_RS12280	COG0840	transmembrane signaling receptor activity
CEQ48_RS12285	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
CEQ48_RS12290	COG2943	transferase activity, transferring hexosyl groups
CEQ48_RS12295	COG1609	Transcriptional regulator
CEQ48_RS12300	COG3394	polysaccharide catabolic process
CEQ48_RS12305	COG1486	melibiose metabolic process
CEQ48_RS12310	COG1447	Phosphotransferase system cellobiose-specific component IIA
CEQ48_RS12320	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CEQ48_RS12325	COG0726	polysaccharide deacetylase
CEQ48_RS12330	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CEQ48_RS12335	COG1846	Transcriptional regulator
CEQ48_RS12365	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CEQ48_RS12380	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CEQ48_RS12385	COG3108	Peptidase M15
CEQ48_RS12415	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CEQ48_RS12425	COG2814	Major facilitator Superfamily
CEQ48_RS12435	COG1054	Belongs to the UPF0176 family
CEQ48_RS12440	COG1278	Cold shock
CEQ48_RS12450	COG4235	cytochrome complex assembly
CEQ48_RS12450	COG3088	subunit of a heme lyase
CEQ48_RS12460	COG1138	Cytochrome C-type biogenesis protein
CEQ48_RS12465	COG3301	Polysulphide reductase, NrfD
CEQ48_RS12470	COG0437	4 iron, 4 sulfur cluster binding
CEQ48_RS12480	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
CEQ48_RS12495	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CEQ48_RS12500	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CEQ48_RS12505	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CEQ48_RS12555	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
CEQ48_RS12560	COG4139	cobalamin transport
CEQ48_RS12565	COG2988	succinylglutamate desuccinylase activity
CEQ48_RS12580	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CEQ48_RS12585	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CEQ48_RS12590	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CEQ48_RS12595	COG1823	symporter activity
CEQ48_RS12600	COG2925	Exonuclease
CEQ48_RS12605	COG1380	Effector of murein hydrolase LrgA
CEQ48_RS12610	COG1346	cytolysis
CEQ48_RS12650	COG0776	regulation of translation
CEQ48_RS12655	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CEQ48_RS12655	COG0072	phenylalanine-tRNA ligase activity
CEQ48_RS12660	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CEQ48_RS12700	COG0322	excinuclease ABC activity
CEQ48_RS12705	COG2197	response regulator
CEQ48_RS12710	COG0417	DNA replication proofreading
CEQ48_RS12715	COG5001	Diguanylate cyclase
CEQ48_RS12725	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CEQ48_RS12730	COG3099	Belongs to the UPF0263 family
CEQ48_RS12745	COG1228	amidohydrolase
CEQ48_RS12750	COG0010	Belongs to the arginase family
CEQ48_RS12755	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CEQ48_RS12760	COG2986	histidine ammonia-lyase
CEQ48_RS12780	COG0277	FAD linked oxidase domain protein
CEQ48_RS12780	COG0247	lactate metabolic process
CEQ48_RS12800	COG2885	chlorophyll binding
CEQ48_RS12820	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CEQ48_RS12830	COG0281	malic enzyme
CEQ48_RS12840	COG2949	membrane
CEQ48_RS12850	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CEQ48_RS12860	COG0492	ferredoxin-NADP+ reductase activity
CEQ48_RS12865	COG4988	ABC transporter
CEQ48_RS12870	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CEQ48_RS12875	COG1187	pseudouridine synthase activity
CEQ48_RS12880	COG0009	L-threonylcarbamoyladenylate synthase
CEQ48_RS12885	COG0613	PHP domain protein
CEQ48_RS12895	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CEQ48_RS12900	COG0512	Glutamine amidotransferase of anthranilate synthase
CEQ48_RS12905	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CEQ48_RS12910	COG0135	phosphoribosylanthranilate isomerase activity
CEQ48_RS12910	COG0134	indole-3-glycerol-phosphate synthase activity
CEQ48_RS12915	COG0133	tryptophan synthase activity
CEQ48_RS12920	COG0159	tryptophan synthase activity
CEQ48_RS12930	COG1435	thymidine kinase activity
CEQ48_RS12935	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CEQ48_RS12940	COG1801	Protein of unknown function DUF72
CEQ48_RS12945	COG4106	trans-aconitate 2-methyltransferase activity
CEQ48_RS12950	COG0500	methyltransferase
CEQ48_RS12955	COG0189	ligase activity
CEQ48_RS12955	COG4067	protein conserved in archaea
CEQ48_RS12970	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CEQ48_RS12980	COG3852	Histidine kinase
CEQ48_RS12995	COG3070	regulator of competence-specific genes
CEQ48_RS13005	COG2431	L-lysine efflux transmembrane transporter activity
CEQ48_RS13015	COG0076	glutamate decarboxylase activity
CEQ48_RS13020	COG1737	Transcriptional regulator
CEQ48_RS13025	COG1012	belongs to the aldehyde dehydrogenase family
CEQ48_RS13025	COG1454	alcohol dehydrogenase
CEQ48_RS13030	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CEQ48_RS13035	COG2985	domain, Protein
CEQ48_RS13035	COG3273	potassium ion transport
CEQ48_RS13040	COG0542	response to heat
CEQ48_RS13045	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CEQ48_RS13050	COG1278	Cold shock
CEQ48_RS13060	COG1187	pseudouridine synthase activity
CEQ48_RS13065	COG0140	phosphoribosyl-ATP diphosphatase activity
CEQ48_RS13065	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CEQ48_RS13070	COG0107	imidazoleglycerol-phosphate synthase activity
CEQ48_RS13075	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CEQ48_RS13080	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CEQ48_RS13085	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CEQ48_RS13085	COG0131	Imidazoleglycerol-phosphate dehydratase
CEQ48_RS13090	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CEQ48_RS13095	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CEQ48_RS13100	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CEQ48_RS13105	COG1757	Na H antiporter
CEQ48_RS13110	COG2916	Histone family protein nucleoid-structuring protein H-NS
CEQ48_RS13115	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CEQ48_RS13120	COG0482	sulfurtransferase activity
CEQ48_RS13125	COG2915	High frequency lysogenization protein hflD homolog
CEQ48_RS13130	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CEQ48_RS13140	COG2268	Band 7 protein
CEQ48_RS13150	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CEQ48_RS13165	COG0300	oxidoreductase activity
CEQ48_RS13175	COG0501	Belongs to the peptidase M48B family
CEQ48_RS13185	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CEQ48_RS13190	COG2226	methyltransferase
CEQ48_RS13195	COG0156	8-amino-7-oxononanoate synthase activity
CEQ48_RS13200	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CEQ48_RS13205	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CEQ48_RS13210	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CEQ48_RS13215	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CEQ48_RS13220	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CEQ48_RS13225	COG0653	protein targeting
CEQ48_RS13230	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CEQ48_RS13235	COG3706	GGDEF domain
CEQ48_RS13245	COG4120	Belongs to the binding-protein-dependent transport system permease family
CEQ48_RS13255	COG4628	conserved protein (DUF2132)
CEQ48_RS13260	COG3092	negative regulation of chromosome organization
CEQ48_RS13265	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CEQ48_RS13270	COG0280	phosphate acetyltransferase
CEQ48_RS13270	COG0857	belongs to the CobB CobQ family
CEQ48_RS13275	COG0435	Glutathione S-transferase
CEQ48_RS13280	COG4608	Belongs to the ABC transporter superfamily
CEQ48_RS13285	COG0444	Belongs to the ABC transporter superfamily
CEQ48_RS13290	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CEQ48_RS13295	COG0601	transmembrane transport
CEQ48_RS13315	COG2204	response regulator
CEQ48_RS13320	COG3300	MHYT domain
CEQ48_RS13320	COG5001	Diguanylate cyclase
CEQ48_RS13325	COG4191	Histidine kinase
CEQ48_RS13330	COG5002	protein histidine kinase activity
CEQ48_RS13340	COG2201	protein-glutamate methylesterase activity
CEQ48_RS13355	COG0009	L-threonylcarbamoyladenylate synthase
CEQ48_RS13390	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEQ48_RS13395	COG3716	PTS system mannose fructose sorbose family IID component
CEQ48_RS13405	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEQ48_RS13410	COG2222	sugar isomerase
CEQ48_RS13420	COG1349	DNA-binding transcription factor activity
CEQ48_RS13425	COG1349	DNA-binding transcription factor activity
CEQ48_RS13440	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CEQ48_RS13445	COG0640	Transcriptional regulator
CEQ48_RS13525	COG0732	type I restriction modification DNA specificity domain
CEQ48_RS13550	COG1396	sequence-specific DNA binding
CEQ48_RS13575	COG3706	GGDEF domain
CEQ48_RS13595	COG1946	Acyl-CoA thioesterase
CEQ48_RS13600	COG1522	sequence-specific DNA binding
CEQ48_RS13610	COG0616	signal peptide processing
CEQ48_RS13615	COG1028	Short-chain dehydrogenase reductase Sdr
CEQ48_RS13620	COG2983	Belongs to the UPF0260 family
CEQ48_RS13630	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CEQ48_RS13635	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CEQ48_RS13640	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CEQ48_RS13645	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CEQ48_RS13650	COG2832	Protein of unknown function (DUF454)
CEQ48_RS13660	COG0745	RESPONSE REGULATOR receiver
CEQ48_RS13665	COG0583	DNA-binding transcription factor activity
CEQ48_RS13670	COG0778	Nitroreductase
CEQ48_RS13675	COG1250	3-hydroxyacyl-CoA dehydrogenase
CEQ48_RS13675	COG1024	Enoyl-CoA hydratase
CEQ48_RS13680	COG0183	Belongs to the thiolase family
CEQ48_RS13695	COG2067	long-chain fatty acid transport protein
CEQ48_RS13705	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CEQ48_RS13710	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
CEQ48_RS13715	COG2982	Protein involved in outer membrane biogenesis
CEQ48_RS13720	COG0572	uridine kinase
CEQ48_RS13730	COG0489	protein tyrosine kinase activity
CEQ48_RS13735	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CEQ48_RS13735	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CEQ48_RS13750	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
CEQ48_RS13765	COG0517	IMP dehydrogenase activity
CEQ48_RS13765	COG0617	tRNA 3'-terminal CCA addition
CEQ48_RS13765	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CEQ48_RS13770	COG2199	diguanylate cyclase activity
CEQ48_RS13775	COG0314	molybdopterin synthase activity
CEQ48_RS13780	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CEQ48_RS13785	COG0315	cyclic pyranopterin monophosphate synthase activity
CEQ48_RS13790	COG0521	Mo-molybdopterin cofactor biosynthetic process
CEQ48_RS13795	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CEQ48_RS13800	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CEQ48_RS13805	COG2198	Histidine kinase
CEQ48_RS13810	COG2204	response regulator
CEQ48_RS13820	COG0556	nucleotide-excision repair
CEQ48_RS13830	COG4657	Part of a membrane complex involved in electron transport
CEQ48_RS13835	COG2878	Part of a membrane complex involved in electron transport
CEQ48_RS13840	COG4656	Part of a membrane complex involved in electron transport
CEQ48_RS13855	COG4660	Part of a membrane complex involved in electron transport
CEQ48_RS13860	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CEQ48_RS13865	COG0346	lactoylglutathione lyase activity
CEQ48_RS13885	COG2056	Na+-H+ antiporter family
CEQ48_RS13890	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CEQ48_RS13895	COG1286	toxin biosynthetic process
CEQ48_RS13900	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
CEQ48_RS13905	COG0285	dihydrofolate synthase activity
CEQ48_RS13910	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CEQ48_RS13915	COG0101	tRNA pseudouridine synthase activity
CEQ48_RS13930	COG2190	(PTS) system
CEQ48_RS13930	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEQ48_RS13930	COG1263	PTS System
CEQ48_RS13935	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CEQ48_RS13940	COG1940	carbohydrate kinase activity
CEQ48_RS13940	COG1846	Transcriptional regulator
CEQ48_RS13945	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CEQ48_RS13945	COG4651	solute:proton antiporter activity
CEQ48_RS13950	COG0367	asparagine synthase
CEQ48_RS13960	COG3104	oligopeptide transport
CEQ48_RS13965	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CEQ48_RS13970	COG0563	adenylate kinase activity
CEQ48_RS13975	COG0326	Molecular chaperone. Has ATPase activity
CEQ48_RS13980	COG3710	Transcriptional regulator
CEQ48_RS13995	COG0622	Phosphoesterase
CEQ48_RS14000	COG1090	epimerase
CEQ48_RS14005	COG0300	oxidoreductase activity
CEQ48_RS14010	COG3118	belongs to the thioredoxin family
CEQ48_RS14020	COG0330	HflC and HflK could
CEQ48_RS14025	COG1585	Membrane protein implicated in regulation of membrane protease activity
CEQ48_RS14030	COG0789	Transcriptional regulator
CEQ48_RS14045	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CEQ48_RS14050	COG3115	cell septum assembly
CEQ48_RS14060	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CEQ48_RS14070	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEQ48_RS14080	COG2190	(PTS) system
CEQ48_RS14085	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CEQ48_RS14090	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CEQ48_RS14095	COG1702	phosphate starvation-inducible protein PhoH
CEQ48_RS14100	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CEQ48_RS14105	COG4535	Mg2 and Co2 transporter CorC
CEQ48_RS14110	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CEQ48_RS14115	COG2888	peptidyl-tyrosine sulfation
CEQ48_RS14120	COG0495	leucyl-tRNA aminoacylation
CEQ48_RS14125	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
CEQ48_RS14130	COG1466	dna polymerase III delta subunit
CEQ48_RS14135	COG0799	negative regulation of ribosome biogenesis
CEQ48_RS14140	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CEQ48_RS14145	COG0768	penicillin binding
CEQ48_RS14150	COG0772	Belongs to the SEDS family
CEQ48_RS14155	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CEQ48_RS14160	COG1686	Belongs to the peptidase S11 family
CEQ48_RS14165	COG2921	Belongs to the UPF0250 family
CEQ48_RS14170	COG0321	lipoyl(octanoyl) transferase activity
CEQ48_RS14175	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CEQ48_RS14185	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CEQ48_RS14250	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
CEQ48_RS14260	COG0438	transferase activity, transferring glycosyl groups
CEQ48_RS14270	COG1045	serine acetyltransferase
CEQ48_RS14290	COG0110	maltose O-acetyltransferase activity
CEQ48_RS14295	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CEQ48_RS14300	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CEQ48_RS14305	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CEQ48_RS14310	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CEQ48_RS14350	COG2205	protein histidine kinase activity
CEQ48_RS14355	COG0745	RESPONSE REGULATOR receiver
CEQ48_RS14360	COG0366	Alpha amylase catalytic
CEQ48_RS14365	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEQ48_RS14365	COG1263	PTS System
CEQ48_RS14370	COG1609	Transcriptional regulator
CEQ48_RS14375	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CEQ48_RS14380	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CEQ48_RS14385	COG2011	ABC-type metal ion transport system permease component
CEQ48_RS14390	COG1464	Belongs to the NlpA lipoprotein family
CEQ48_RS14395	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
CEQ48_RS14405	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CEQ48_RS14405	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CEQ48_RS14420	COG1611	Belongs to the LOG family
CEQ48_RS14425	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CEQ48_RS14430	COG2363	Small membrane protein
CEQ48_RS14435	COG0583	DNA-binding transcription factor activity
CEQ48_RS14445	COG0301	tRNA thio-modification
CEQ48_RS14445	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CEQ48_RS14455	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CEQ48_RS14460	COG1722	exodeoxyribonuclease VII activity
CEQ48_RS14465	COG0142	geranyltranstransferase activity
CEQ48_RS14470	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CEQ48_RS14475	COG0564	pseudouridine synthase activity
CEQ48_RS14480	COG3098	single-species biofilm formation
CEQ48_RS14505	COG1671	Belongs to the UPF0178 family
CEQ48_RS14510	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CEQ48_RS14515	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CEQ48_RS14520	COG0254	rRNA binding
CEQ48_RS14525	COG1720	tRNA m6t6A37 methyltransferase activity
CEQ48_RS14530	COG0442	prolyl-tRNA aminoacylation
CEQ48_RS14550	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CEQ48_RS14550	COG0047	phosphoribosylformylglycinamidine synthase activity
CEQ48_RS14560	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
CEQ48_RS14565	COG0590	tRNA wobble adenosine to inosine editing
CEQ48_RS14570	COG0583	DNA-binding transcription factor activity
CEQ48_RS14580	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CEQ48_RS14585	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CEQ48_RS14620	COG0484	heat shock protein binding
CEQ48_RS14625	COG0443	Heat shock 70 kDa protein
CEQ48_RS14635	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
CEQ48_RS14650	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CEQ48_RS14655	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CEQ48_RS14660	COG0497	DNA recombination
CEQ48_RS14665	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CEQ48_RS14670	COG2914	Belongs to the UPF0125 (RnfH) family
CEQ48_RS14675	COG2867	negative regulation of translational initiation
CEQ48_RS14680	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CEQ48_RS14715	COG1061	Type III restriction enzyme res subunit
CEQ48_RS14730	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
CEQ48_RS14735	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CEQ48_RS14740	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CEQ48_RS14755	COG3051	citrate lyase alpha subunit
CEQ48_RS14760	COG2301	Belongs to the HpcH HpaI aldolase family
CEQ48_RS14765	COG3052	prosthetic group binding
CEQ48_RS14770	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
CEQ48_RS14780	COG3630	sodium ion export across plasma membrane
CEQ48_RS14785	COG5016	pyruvate
CEQ48_RS14785	COG0511	ligase activity, forming carbon-carbon bonds
CEQ48_RS14790	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
CEQ48_RS14800	COG4565	transcriptional regulatory protein
CEQ48_RS14810	COG2200	EAL domain
CEQ48_RS14820	COG0583	DNA-binding transcription factor activity
CEQ48_RS14830	COG1115	amino acid carrier protein
CEQ48_RS14835	COG2015	COG2015, Alkyl sulfatase and related hydrolases
CEQ48_RS14840	COG0583	DNA-binding transcription factor activity
CEQ48_RS14845	COG1584	GPR1 FUN34 yaaH family protein
CEQ48_RS14865	COG1121	(ABC) transporter
CEQ48_RS14870	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CEQ48_RS14875	COG0523	cobalamin synthesis protein
CEQ48_RS14885	COG0735	belongs to the Fur family
CEQ48_RS14890	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CEQ48_RS14900	COG0523	cobalamin synthesis protein
CEQ48_RS14910	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
CEQ48_RS14915	COG2988	succinylglutamate desuccinylase activity
CEQ48_RS14920	COG0739	heme binding
CEQ48_RS14925	COG2188	Transcriptional regulator
CEQ48_RS14930	COG1263	PTS System
CEQ48_RS14930	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEQ48_RS14935	COG1486	melibiose metabolic process
CEQ48_RS14940	COG1929	Belongs to the glycerate kinase type-1 family
CEQ48_RS14945	COG1162	GTPase activity
CEQ48_RS14955	COG0789	Transcriptional regulator
CEQ48_RS15025	COG0582	viral genome integration into host DNA
CEQ48_RS15030	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CEQ48_RS15030	COG0519	Catalyzes the synthesis of GMP from XMP
CEQ48_RS15035	COG0517	IMP dehydrogenase activity
CEQ48_RS15035	COG0516	GMP reductase activity
CEQ48_RS15055	COG1160	GTP binding
CEQ48_RS15060	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CEQ48_RS15065	COG2976	Protein conserved in bacteria
CEQ48_RS15070	COG0124	histidyl-tRNA synthetase
CEQ48_RS15075	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CEQ48_RS15090	COG0105	UTP biosynthetic process
CEQ48_RS15095	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CEQ48_RS15100	COG2975	iron-sulfur cluster assembly
CEQ48_RS15105	COG0633	Ferredoxin
CEQ48_RS15125	COG0822	iron-sulfur transferase activity
CEQ48_RS15130	COG1104	cysteine desulfurase activity
CEQ48_RS15135	COG1959	2 iron, 2 sulfur cluster binding
CEQ48_RS15145	COG0483	inositol monophosphate 1-phosphatase activity
CEQ48_RS15150	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CEQ48_RS15155	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CEQ48_RS15160	COG1862	Preprotein translocase
CEQ48_RS15175	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CEQ48_RS15180	COG0517	IMP dehydrogenase activity
CEQ48_RS15190	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CEQ48_RS15195	COG0583	DNA-binding transcription factor activity
CEQ48_RS15200	COG0450	alkyl hydroperoxide reductase
CEQ48_RS15205	COG3142	Participates in the control of copper homeostasis
CEQ48_RS15220	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CEQ48_RS15225	COG0581	inorganic phosphate transmembrane transporter activity
CEQ48_RS15235	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CEQ48_RS15240	COG0248	Ppx GppA phosphatase
CEQ48_RS15250	COG5002	protein histidine kinase activity
CEQ48_RS15255	COG0745	RESPONSE REGULATOR receiver
CEQ48_RS15265	COG0826	peptidase U32
CEQ48_RS15270	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CEQ48_RS15325	COG0542	response to heat
CEQ48_RS15330	COG1496	oxidoreductase activity
CEQ48_RS15335	COG0564	pseudouridine synthase activity
CEQ48_RS15340	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CEQ48_RS15345	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CEQ48_RS15350	COG0077	Prephenate dehydratase
CEQ48_RS15350	COG1605	Chorismate mutase
CEQ48_RS15355	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CEQ48_RS15360	COG5001	Diguanylate cyclase
CEQ48_RS15370	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
CEQ48_RS15380	COG0488	(ABC) transporter
CEQ48_RS15390	COG1605	Chorismate mutase
CEQ48_RS15390	COG0287	Prephenate dehydrogenase
CEQ48_RS15395	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CEQ48_RS15400	COG3275	phosphorelay sensor kinase activity
CEQ48_RS15405	COG3279	Response regulator of the LytR AlgR family
CEQ48_RS15415	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CEQ48_RS15420	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CEQ48_RS15435	COG1966	Carbon starvation protein
CEQ48_RS15440	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CEQ48_RS15445	COG1047	Peptidyl-prolyl cis-trans
CEQ48_RS15450	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CEQ48_RS15460	COG0196	riboflavin kinase activity
CEQ48_RS15465	COG0728	peptidoglycan biosynthetic process
CEQ48_RS15470	COG0268	Binds directly to 16S ribosomal RNA
CEQ48_RS15475	COG0640	Transcriptional regulator
CEQ48_RS15480	COG0583	DNA-binding transcription factor activity
CEQ48_RS15485	COG1283	sodium-dependent phosphate transmembrane transporter activity
CEQ48_RS15490	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CEQ48_RS15495	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CEQ48_RS15500	COG0730	response to heat
CEQ48_RS15505	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
CEQ48_RS15510	COG0494	nUDIX hydrolase
CEQ48_RS15520	COG0667	Aldo Keto reductase
CEQ48_RS15530	COG2204	response regulator
CEQ48_RS15535	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CEQ48_RS15555	COG0513	Belongs to the DEAD box helicase family
CEQ48_RS15580	COG3153	acetyltransferase
CEQ48_RS15585	COG3154	lipid carrier protein
CEQ48_RS15595	COG0826	peptidase U32
CEQ48_RS15600	COG0826	peptidase U32
CEQ48_RS15625	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CEQ48_RS15635	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CEQ48_RS15645	COG0195	Participates in both transcription termination and antitermination
CEQ48_RS15650	COG0779	Required for maturation of 30S ribosomal subunits
CEQ48_RS15665	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CEQ48_RS15680	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CEQ48_RS15685	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CEQ48_RS15690	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CEQ48_RS15695	COG1534	Rna-binding protein
CEQ48_RS15700	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CEQ48_RS15705	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CEQ48_RS15710	COG2027	D-alanyl-D-alanine carboxypeptidase
CEQ48_RS15715	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CEQ48_RS15720	COG0739	heme binding
CEQ48_RS15725	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CEQ48_RS15735	COG0316	Belongs to the HesB IscA family
CEQ48_RS15740	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CEQ48_RS15745	COG0628	permease
CEQ48_RS15750	COG2813	Specifically methylates the guanine in position
CEQ48_RS15760	COG0747	negative chemotaxis
CEQ48_RS15770	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CEQ48_RS15775	COG0444	Belongs to the ABC transporter superfamily
CEQ48_RS15780	COG4608	Belongs to the ABC transporter superfamily
CEQ48_RS15790	COG2971	BadF BadG BcrA BcrD
CEQ48_RS15805	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CEQ48_RS15810	COG3842	ATPase activity
CEQ48_RS15820	COG1840	ABC-type Fe3 transport system, periplasmic component
CEQ48_RS15825	COG0004	ammonium transporteR
CEQ48_RS15830	COG0347	Belongs to the P(II) protein family
CEQ48_RS15835	COG3112	Uncharacterised protein family (UPF0231)
CEQ48_RS15840	COG1049	propionate catabolic process, 2-methylcitrate cycle
CEQ48_RS15845	COG1752	Esterase of the alpha-beta hydrolase superfamily
CEQ48_RS15850	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CEQ48_RS15855	COG1643	Atp-dependent helicase
CEQ48_RS15865	COG1489	DNA binding
CEQ48_RS15875	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CEQ48_RS15885	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CEQ48_RS15890	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CEQ48_RS15895	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CEQ48_RS15900	COG0842	Transport permease protein
CEQ48_RS15905	COG1131	(ABC) transporter
CEQ48_RS15910	COG0659	secondary active sulfate transmembrane transporter activity
CEQ48_RS15915	COG0288	reversible hydration of carbon dioxide
CEQ48_RS15935	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CEQ48_RS15940	COG3107	peptidoglycan biosynthetic process
CEQ48_RS15945	COG0792	nuclease activity
CEQ48_RS15950	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CEQ48_RS15955	COG2823	Periplasmic or secreted lipoprotein
CEQ48_RS15960	COG2969	positive regulation of protein catabolic process
CEQ48_RS15965	COG0625	glutathione transferase activity
CEQ48_RS15970	COG2857	Cytochrome c1
CEQ48_RS15975	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CEQ48_RS15980	COG0723	plastoquinol--plastocyanin reductase activity
CEQ48_RS15985	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CEQ48_RS15990	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CEQ48_RS15995	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CEQ48_RS16005	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CEQ48_RS16015	COG0335	large ribosomal subunit rRNA binding
CEQ48_RS16020	COG0336	Belongs to the RNA methyltransferase TrmD family
CEQ48_RS16025	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CEQ48_RS16030	COG0228	four-way junction DNA binding
CEQ48_RS16035	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CEQ48_RS16040	COG4137	Cytochrome C assembly protein
CEQ48_RS16045	COG4536	flavin adenine dinucleotide binding
CEQ48_RS16050	COG1854	S-ribosylhomocysteine lyase activity
CEQ48_RS16055	COG2918	glutathione biosynthetic process
CEQ48_RS16060	COG0612	Peptidase, M16
CEQ48_RS16065	COG1238	metal cluster binding
CEQ48_RS16075	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
CEQ48_RS16080	COG5016	pyruvate
CEQ48_RS16080	COG0511	ligase activity, forming carbon-carbon bonds
CEQ48_RS16085	COG3630	sodium ion export across plasma membrane
CEQ48_RS16130	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CEQ48_RS16135	COG0527	aspartate kinase activity
CEQ48_RS16145	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CEQ48_RS16150	COG2137	regulation of response to DNA damage stimulus
CEQ48_RS16155	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CEQ48_RS16165	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CEQ48_RS16170	COG4208	sulfate ABC transporter
CEQ48_RS16175	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CEQ48_RS16190	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CEQ48_RS16195	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CEQ48_RS16200	COG1388	LysM domain
CEQ48_RS16200	COG4942	peptidase
CEQ48_RS16205	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CEQ48_RS16210	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CEQ48_RS16215	COG0585	pseudouridine synthase activity
CEQ48_RS16220	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CEQ48_RS16225	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CEQ48_RS16230	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CEQ48_RS16235	COG1968	undecaprenyl-diphosphatase activity
CEQ48_RS16240	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CEQ48_RS16255	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CEQ48_RS16265	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CEQ48_RS16270	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CEQ48_RS16275	COG1610	YqeY-like protein
CEQ48_RS16280	COG0358	DNA primase activity
CEQ48_RS16300	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CEQ48_RS16320	COG0419	ATPase involved in DNA repair
CEQ48_RS16380	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CEQ48_RS16385	COG1349	DNA-binding transcription factor activity
CEQ48_RS16410	COG1279	arginine transmembrane transporter activity
CEQ48_RS16415	COG0668	transmembrane transport
CEQ48_RS16420	COG0191	fructose-bisphosphate aldolase activity
CEQ48_RS16425	COG0126	phosphoglycerate kinase activity
CEQ48_RS16430	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CEQ48_RS16435	COG4771	TonB-dependent receptor
CEQ48_RS16440	COG0583	DNA-binding transcription factor activity
CEQ48_RS16445	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CEQ48_RS16450	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CEQ48_RS16460	COG2356	endonuclease I
CEQ48_RS16465	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CEQ48_RS16470	COG0189	ligase activity
CEQ48_RS16475	COG1678	Uncharacterized ACR, COG1678
CEQ48_RS16480	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CEQ48_RS16510	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CEQ48_RS16515	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CEQ48_RS16520	COG0762	integral membrane protein
CEQ48_RS16535	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CEQ48_RS16540	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CEQ48_RS16545	COG2066	Belongs to the glutaminase family
CEQ48_RS16550	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CEQ48_RS16555	COG1194	a g-specific adenine glycosylase
CEQ48_RS16560	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
CEQ48_RS16565	COG0741	lytic transglycosylase activity
CEQ48_RS16625	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CEQ48_RS16630	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CEQ48_RS16635	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CEQ48_RS16640	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CEQ48_RS16645	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CEQ48_RS16650	COG2967	ApaG domain
CEQ48_RS16655	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CEQ48_RS16670	COG3610	response to peptide
CEQ48_RS16675	COG2966	Psort location CytoplasmicMembrane, score
CEQ48_RS16685	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CEQ48_RS16690	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CEQ48_RS16695	COG0142	geranyltranstransferase activity
CEQ48_RS16700	COG0531	amino acid
CEQ48_RS16705	COG0039	L-malate dehydrogenase activity
CEQ48_RS16710	COG1438	arginine binding
CEQ48_RS16720	COG2358	TRAP transporter, solute receptor (TAXI family
CEQ48_RS16730	COG0589	response to stress
CEQ48_RS16755	COG2235	arginine
CEQ48_RS16760	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CEQ48_RS16770	COG0312	modulator of DNA gyrase
CEQ48_RS16775	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CEQ48_RS16780	COG3164	Protein of unknown function
CEQ48_RS16790	COG0424	maF-like protein
CEQ48_RS16795	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CEQ48_RS16800	COG1792	Involved in formation and maintenance of cell shape
CEQ48_RS16805	COG1077	Cell shape determining protein MreB Mrl
CEQ48_RS16840	COG2165	general secretion pathway protein
CEQ48_RS16850	COG1459	type II secretion system
CEQ48_RS16855	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CEQ48_RS16865	COG3267	Type II secretory pathway component ExeA
CEQ48_RS16865	COG3409	Peptidoglycan-binding domain 1 protein
CEQ48_RS16890	COG2200	EAL domain
CEQ48_RS16890	COG2199	diguanylate cyclase activity
CEQ48_RS16925	COG2433	Pfam Transposase IS66
CEQ48_RS16965	COG0629	single-stranded DNA binding
CEQ48_RS16980	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CEQ48_RS16990	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CEQ48_RS16995	COG0527	aspartate kinase activity
CEQ48_RS17000	COG0646	methionine synthase
CEQ48_RS17000	COG1410	methionine synthase
CEQ48_RS17070	COG0175	sulfate reduction
CEQ48_RS17080	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CEQ48_RS17105	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CEQ48_RS17110	COG0735	belongs to the Fur family
CEQ48_RS17125	COG0166	Belongs to the GPI family
CEQ48_RS17130	COG0432	Pfam Uncharacterised protein family UPF0047
CEQ48_RS17135	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CEQ48_RS17150	COG0359	binds to the 23S rRNA
CEQ48_RS17155	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CEQ48_RS17160	COG2965	DNA replication, synthesis of RNA primer
CEQ48_RS17165	COG0360	Binds together with S18 to 16S ribosomal RNA
CEQ48_RS17175	COG2906	2 iron, 2 sulfur cluster binding
CEQ48_RS17180	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CEQ48_RS17185	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CEQ48_RS17190	COG0049	tRNA binding
CEQ48_RS17205	COG2923	Belongs to the DsrF TusC family
CEQ48_RS17210	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CEQ48_RS17215	COG2964	Protein conserved in bacteria
CEQ48_RS17220	COG0545	Peptidyl-prolyl cis-trans isomerase
CEQ48_RS17230	COG2900	Belongs to the SlyX family
CEQ48_RS17235	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
CEQ48_RS17240	COG0330	HflC and HflK could
CEQ48_RS17245	COG0330	HflC and HflK could
CEQ48_RS17250	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CEQ48_RS17255	COG1923	regulation of RNA biosynthetic process
CEQ48_RS17260	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CEQ48_RS17265	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CEQ48_RS17275	COG0802	atpase or kinase
CEQ48_RS17280	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CEQ48_RS17330	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CEQ48_RS17340	COG0688	phosphatidylethanolamine metabolic process
CEQ48_RS17345	COG0471	metal ion transport
CEQ48_RS17355	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CEQ48_RS17360	COG4942	peptidase
CEQ48_RS17375	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CEQ48_RS17380	COG2816	NAD+ diphosphatase activity
CEQ48_RS17385	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
CEQ48_RS17390	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CEQ48_RS17395	COG0085	RNA polymerase activity
CEQ48_RS17400	COG0222	ribosome binding
CEQ48_RS17405	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CEQ48_RS17415	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CEQ48_RS17420	COG0250	Participates in transcription elongation, termination and antitermination
CEQ48_RS17425	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CEQ48_RS17430	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CEQ48_RS17455	COG1072	(Pantothenic acid kinase))
CEQ48_RS17465	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CEQ48_RS17475	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CEQ48_RS17520	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CEQ48_RS17535	COG3118	belongs to the thioredoxin family
CEQ48_RS17540	COG0513	Belongs to the DEAD box helicase family
CEQ48_RS17545	COG0248	Ppx GppA phosphatase
CEQ48_RS17550	COG2202	Pas domain
CEQ48_RS17550	COG2205	protein histidine kinase activity
CEQ48_RS17555	COG2814	Major facilitator Superfamily
CEQ48_RS17575	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CEQ48_RS17580	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CEQ48_RS17585	COG0511	ligase activity, forming carbon-carbon bonds
CEQ48_RS17590	COG0439	Biotin carboxylase
CEQ48_RS17595	COG2264	protein methyltransferase activity
CEQ48_RS17600	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CEQ48_RS17605	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
CEQ48_RS17610	COG1609	Transcriptional regulator
CEQ48_RS17615	COG0129	dihydroxy-acid dehydratase activity
CEQ48_RS17620	COG3265	gluconokinase activity
CEQ48_RS17630	COG0800	Aldolase
CEQ48_RS17635	COG1982	Orn Lys Arg decarboxylase major
CEQ48_RS17640	COG0531	amino acid
CEQ48_RS17645	COG3710	Transcriptional regulator
CEQ48_RS17650	COG0789	Transcriptional regulator
CEQ48_RS17665	COG0151	Belongs to the GarS family
CEQ48_RS17675	COG0776	regulation of translation
CEQ48_RS17680	COG1253	flavin adenine dinucleotide binding
CEQ48_RS17690	COG3068	Protein conserved in bacteria
CEQ48_RS17695	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CEQ48_RS17700	COG1573	uracil-dna glycosylase
CEQ48_RS17705	COG0668	transmembrane transport
CEQ48_RS17710	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CEQ48_RS17720	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CEQ48_RS17740	COG1086	Polysaccharide biosynthesis protein
CEQ48_RS17785	COG1596	polysaccharide export
CEQ48_RS17805	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CEQ48_RS17855	COG1213	nucleotidyl transferase
CEQ48_RS17865	COG0574	Belongs to the PEP-utilizing enzyme family
CEQ48_RS17865	COG3848	Pyruvate phosphate dikinase
CEQ48_RS17875	COG1216	Glycosyl transferase, family 2
CEQ48_RS17880	COG1132	(ABC) transporter
CEQ48_RS17900	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CEQ48_RS17910	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CEQ48_RS17920	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CEQ48_RS17955	COG1519	Transferase
CEQ48_RS17985	COG3642	lipopolysaccharide core region biosynthetic process
CEQ48_RS17990	COG0859	PFAM glycosyl transferase family 9
CEQ48_RS17995	COG0463	Glycosyl transferase, family 2
CEQ48_RS18000	COG0859	PFAM glycosyl transferase family 9
CEQ48_RS18005	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CEQ48_RS18010	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CEQ48_RS18020	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CEQ48_RS18025	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CEQ48_RS18030	COG2003	Belongs to the UPF0758 family
CEQ48_RS18040	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CEQ48_RS18050	COG1309	transcriptional regulator
CEQ48_RS18055	COG1560	Kdo2-lipid A biosynthetic process
CEQ48_RS18060	COG1560	Kdo2-lipid A biosynthetic process
CEQ48_RS18065	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CEQ48_RS18070	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CEQ48_RS18075	COG1561	YicC-like family, N-terminal region
CEQ48_RS18105	COG2003	Belongs to the UPF0758 family
CEQ48_RS18150	COG2831	hemolysin activation secretion protein
CEQ48_RS18165	COG0328	RNA-DNA hybrid ribonuclease activity
CEQ48_RS18235	COG2862	Uncharacterized protein family, UPF0114
CEQ48_RS18240	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEQ48_RS18240	COG1263	PTS System
CEQ48_RS18245	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CEQ48_RS18265	COG0514	ATP-dependent DNA helicase (RecQ)
CEQ48_RS18270	COG2962	Rard protein
CEQ48_RS18275	COG0405	Gamma-glutamyltransferase
CEQ48_RS18285	COG1280	lysine exporter protein (LysE YggA)
CEQ48_RS18290	COG0210	DNA helicase
CEQ48_RS18300	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CEQ48_RS18305	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CEQ48_RS18315	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CEQ48_RS18320	COG0601	transmembrane transport
CEQ48_RS18325	COG0747	negative chemotaxis
CEQ48_RS18420	COG4964	Belongs to the GSP D family
CEQ48_RS18455	COG1309	transcriptional regulator
CEQ48_RS18460	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CEQ48_RS18465	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CEQ48_RS18470	COG2960	long-chain fatty acid transporting porin activity
CEQ48_RS18475	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CEQ48_RS18480	COG0583	DNA-binding transcription factor activity
CEQ48_RS18550	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
CEQ48_RS18555	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CEQ48_RS18565	COG1250	3-hydroxyacyl-CoA dehydrogenase
CEQ48_RS18565	COG1024	Enoyl-CoA hydratase
CEQ48_RS18570	COG0183	Belongs to the thiolase family
CEQ48_RS18575	COG0583	DNA-binding transcription factor activity
CEQ48_RS18580	COG2814	Major facilitator Superfamily
CEQ48_RS18590	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CEQ48_RS18595	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CEQ48_RS18600	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CEQ48_RS18605	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CEQ48_RS18610	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CEQ48_RS18615	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CEQ48_RS18625	COG0356	it plays a direct role in the translocation of protons across the membrane
CEQ48_RS18630	COG3312	ion transport
CEQ48_RS18635	COG1475	DNA binding
CEQ48_RS18640	COG1192	Involved in chromosome partitioning
CEQ48_RS18645	COG0357	Ribosomal RNA small subunit methyltransferase G
CEQ48_RS18650	COG0445	tRNA wobble uridine modification
CEQ48_RS18660	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CEQ48_RS18665	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CEQ48_RS18670	COG0706	membrane insertase activity
CEQ48_RS18680	COG0594	ribonuclease P activity
CEQ48_RS18685	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CEQ48_RS18690	COG1126	abc transporter atp-binding protein
CEQ48_RS18705	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CEQ48_RS18710	COG0592	DNA-directed DNA polymerase activity
CEQ48_RS18715	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CEQ48_RS18720	COG0187	DNA topoisomerase II activity
CEQ48_RS18735	COG0071	Belongs to the small heat shock protein (HSP20) family
CEQ48_RS18740	COG3977	Valine--pyruvate aminotransferase
CEQ48_RS18745	COG0751	glycine-tRNA ligase activity
CEQ48_RS18750	COG0752	glycyl-tRNA synthetase alpha subunit
CEQ48_RS18755	COG2119	membrane
CEQ48_RS18765	COG0425	Belongs to the sulfur carrier protein TusA family
CEQ48_RS18775	COG0604	alcohol dehydrogenase
CEQ48_RS18790	COG0129	dihydroxy-acid dehydratase activity
CEQ48_RS18795	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CEQ48_RS18810	COG0606	chelatase, subunit chli
CEQ48_RS18815	COG0204	Acyl-transferase
CEQ48_RS18820	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CEQ48_RS18825	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CEQ48_RS18835	COG3084	Protein conserved in bacteria
CEQ48_RS18845	COG4326	sporulation control protein
CEQ48_RS18850	COG1272	protein, Hemolysin III
CEQ48_RS18860	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CEQ48_RS18865	COG0569	domain protein
CEQ48_RS18870	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CEQ48_RS18870	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CEQ48_RS18875	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CEQ48_RS18880	COG0242	peptide deformylase activity
CEQ48_RS18885	COG1652	LysM domain
CEQ48_RS18890	COG0758	DNA mediated transformation
CEQ48_RS18895	COG2922	Belongs to the Smg family
CEQ48_RS18900	COG0551	DNA topoisomerase type I activity
CEQ48_RS18905	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CEQ48_RS18910	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CEQ48_RS18915	COG0009	L-threonylcarbamoyladenylate synthase
CEQ48_RS18920	COG0408	coproporphyrinogen oxidase activity
CEQ48_RS18925	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CEQ48_RS18935	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CEQ48_RS18980	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CEQ48_RS18985	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CEQ48_RS18995	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CEQ48_RS19000	COG2104	thiamine diphosphate biosynthetic process
CEQ48_RS19005	COG2022	thiamine diphosphate biosynthetic process
CEQ48_RS19010	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CEQ48_RS19015	COG0006	proline dipeptidase activity
CEQ48_RS19015	COG0006	proline dipeptidase activity
CEQ48_RS19035	COG1522	sequence-specific DNA binding
CEQ48_RS19040	COG5002	protein histidine kinase activity
CEQ48_RS19040	COG5001	Diguanylate cyclase
CEQ48_RS19060	COG0589	response to stress
CEQ48_RS19070	COG1528	Iron-storage protein
CEQ48_RS19080	COG2081	HI0933 family
CEQ48_RS19135	COG0840	transmembrane signaling receptor activity
CEQ48_RS19145	COG1322	Protein conserved in bacteria
CEQ48_RS19150	COG2226	methyltransferase
CEQ48_RS19165	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CEQ48_RS19170	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CEQ48_RS19175	COG0805	protein transport
CEQ48_RS19180	COG1858	cytochrome C peroxidase
CEQ48_RS19185	COG0534	Mate efflux family protein
CEQ48_RS19195	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CEQ48_RS19205	COG2937	Belongs to the GPAT DAPAT family
CEQ48_RS19210	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CEQ48_RS19215	COG3161	chorismate lyase activity
CEQ48_RS19225	COG1580	Controls the rotational direction of flagella during chemotaxis
CEQ48_RS19235	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CEQ48_RS19245	COG0084	hydrolase, TatD family'
CEQ48_RS19265	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CEQ48_RS19265	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CEQ48_RS19285	COG3078	GTPase activator activity
CEQ48_RS19300	COG3071	HemY protein
CEQ48_RS19305	COG2959	enzyme of heme biosynthesis
CEQ48_RS19310	COG1587	Uroporphyrinogen-III synthase
CEQ48_RS19315	COG0181	hydroxymethylbilane synthase activity
CEQ48_RS19325	COG3072	Adenylate cyclase
CEQ48_RS19330	COG1965	Belongs to the frataxin family
CEQ48_RS19340	COG0019	diaminopimelate decarboxylase activity
CEQ48_RS19345	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CEQ48_RS19355	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CEQ48_RS19360	COG1011	Hydrolase
CEQ48_RS19365	COG2199	diguanylate cyclase activity
CEQ48_RS19365	COG2200	EAL domain
CEQ48_RS19365	COG3287	FIST C domain
CEQ48_RS19385	COG0561	phosphatase activity
CEQ48_RS19390	COG2267	carboxylic ester hydrolase activity
CEQ48_RS19395	COG1280	lysine exporter protein (LysE YggA)
CEQ48_RS19400	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
CEQ48_RS19405	COG0783	Belongs to the Dps family
CEQ48_RS19440	COG0742	ribosomal rna small subunit methyltransferase
CEQ48_RS19445	COG0552	protein localization to endoplasmic reticulum
CEQ48_RS19450	COG2884	Cell division ATP-binding protein ftsE
CEQ48_RS19455	COG2177	Part of the ABC transporter FtsEX involved in
CEQ48_RS19460	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CEQ48_RS19465	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CEQ48_RS19480	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CEQ48_RS19495	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CEQ48_RS19575	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CEQ48_RS19580	COG3300	MHYT domain
CEQ48_RS19580	COG5001	Diguanylate cyclase
CEQ48_RS19590	COG3852	Histidine kinase
CEQ48_RS19600	COG0174	glutamine synthetase
CEQ48_RS19610	COG1217	gtp-binding protein TYPA
CEQ48_RS19615	COG1660	Displays ATPase and GTPase activities
CEQ48_RS19620	COG1295	ribonuclease BN
CEQ48_RS19625	COG1490	D-aminoacyl-tRNA deacylase activity
CEQ48_RS19630	COG0456	acetyltransferase
CEQ48_RS19640	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
CEQ48_RS19645	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CEQ48_RS19650	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CEQ48_RS19655	COG3031	protein transport across the cell outer membrane
CEQ48_RS19665	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CEQ48_RS19670	COG1459	type II secretion system
CEQ48_RS19675	COG2165	general secretion pathway protein
CEQ48_RS19680	COG2165	general secretion pathway protein
CEQ48_RS19685	COG2165	general secretion pathway protein
CEQ48_RS19690	COG4795	General secretion pathway protein
CEQ48_RS19695	COG3156	type II secretion system protein K
CEQ48_RS19700	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
CEQ48_RS19705	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
CEQ48_RS19715	COG1218	3'(2'),5'-bisphosphate nucleotidase
CEQ48_RS19720	COG0494	nUDIX hydrolase
CEQ48_RS19730	COG1040	competence protein
CEQ48_RS19735	COG0596	Alpha beta hydrolase
CEQ48_RS19745	COG2183	response to ionizing radiation
CEQ48_RS19750	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CEQ48_RS19765	COG1129	ABC transporter