locus-tag	class	description
EAE30_RS00015	COG2433	Pfam Transposase IS66
EAE30_RS00035	COG3290	protein histidine kinase activity
EAE30_RS00065	COG0604	alcohol dehydrogenase
EAE30_RS00070	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EAE30_RS00075	COG3118	belongs to the thioredoxin family
EAE30_RS00085	COG2926	Belongs to the UPF0265 family
EAE30_RS00095	COG3132	Protein of unknown function, DUF480
EAE30_RS00100	COG2827	Endonuclease containing a URI domain
EAE30_RS00215	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EAE30_RS00225	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EAE30_RS00240	COG0110	maltose O-acetyltransferase activity
EAE30_RS00255	COG2433	Pfam Transposase IS66
EAE30_RS00315	COG1275	C4-dicarboxylate transporter malic acid transport protein
EAE30_RS00360	COG3300	MHYT domain
EAE30_RS00360	COG5001	Diguanylate cyclase
EAE30_RS00405	COG1309	transcriptional regulator
EAE30_RS00415	COG3604	Transcriptional regulator
EAE30_RS00425	COG3094	Invasion gene expression up-regulator, SirB
EAE30_RS00440	COG3344	reverse transcriptase
EAE30_RS00475	COG5002	protein histidine kinase activity
EAE30_RS00475	COG0784	Response regulator, receiver
EAE30_RS00485	COG0725	ABC transporter, periplasmic molybdate-binding protein
EAE30_RS00490	COG4149	molybdate abc transporter
EAE30_RS00495	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
EAE30_RS00510	COG1289	transmembrane transporter activity
EAE30_RS00515	COG0210	DNA helicase
EAE30_RS00520	COG1335	isochorismatase
EAE30_RS00535	COG1803	Methylglyoxal synthase
EAE30_RS00540	COG1979	alcohol dehydrogenase
EAE30_RS00545	COG2207	Transcriptional regulator
EAE30_RS00550	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EAE30_RS00560	COG3850	Histidine kinase
EAE30_RS00565	COG2197	response regulator
EAE30_RS00575	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EAE30_RS00590	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EAE30_RS00595	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EAE30_RS00605	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
EAE30_RS00610	COG2897	thiosulfate sulfurtransferase activity
EAE30_RS00615	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EAE30_RS00630	COG1454	alcohol dehydrogenase
EAE30_RS00635	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
EAE30_RS00640	COG0583	DNA-binding transcription factor activity
EAE30_RS00650	COG2188	Transcriptional regulator
EAE30_RS00675	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EAE30_RS00680	COG0667	Aldo Keto reductase
EAE30_RS00695	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EAE30_RS00700	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EAE30_RS00710	COG4104	PAAR repeat-containing protein
EAE30_RS00810	COG2010	Cytochrome c
EAE30_RS00850	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
EAE30_RS00860	COG0384	phenazine biosynthesis protein PhzF
EAE30_RS00875	COG1028	Short-chain dehydrogenase reductase Sdr
EAE30_RS00885	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EAE30_RS00915	COG1760	l-serine dehydratase
EAE30_RS00940	COG0446	pyridine nucleotide-disulphide oxidoreductase
EAE30_RS00940	COG1902	pentaerythritol trinitrate reductase activity
EAE30_RS00945	COG0247	lactate metabolic process
EAE30_RS00945	COG2181	nitrate reductase activity
EAE30_RS00950	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
EAE30_RS00960	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EAE30_RS00975	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EAE30_RS00980	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
EAE30_RS00985	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EAE30_RS01015	COG0444	Belongs to the ABC transporter superfamily
EAE30_RS01020	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EAE30_RS01025	COG0601	transmembrane transport
EAE30_RS01065	COG1953	Uracil, thiamine, allantoin
EAE30_RS01075	COG0765	amino acid transport
EAE30_RS01080	COG0765	amino acid transport
EAE30_RS01110	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EAE30_RS01120	COG0402	S-adenosylhomocysteine deaminase activity
EAE30_RS01140	COG0745	RESPONSE REGULATOR receiver
EAE30_RS01155	COG3140	Belongs to the UPF0181 family
EAE30_RS01165	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EAE30_RS01170	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EAE30_RS01180	COG0023	Translation Initiation Factor
EAE30_RS01195	COG1181	Belongs to the D-alanine--D-alanine ligase family
EAE30_RS01205	COG1042	CoA-binding domain protein
EAE30_RS01205	COG0045	succinate-CoA ligase (ADP-forming) activity
EAE30_RS01205	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EAE30_RS01210	COG0583	DNA-binding transcription factor activity
EAE30_RS01215	COG4533	DNA binding
EAE30_RS01225	COG2050	protein possibly involved in aromatic compounds catabolism
EAE30_RS01230	COG2824	Alkylphosphonate utilization operon protein PhnA
EAE30_RS01240	COG0737	Belongs to the 5'-nucleotidase family
EAE30_RS01245	COG3593	DNA synthesis involved in DNA repair
EAE30_RS01265	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
EAE30_RS01270	COG1028	Short-chain dehydrogenase reductase Sdr
EAE30_RS01295	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EAE30_RS01300	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EAE30_RS01315	COG0346	lactoylglutathione lyase activity
EAE30_RS01380	COG0243	molybdopterin cofactor binding
EAE30_RS01400	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EAE30_RS01405	COG0523	cobalamin synthesis protein
EAE30_RS01415	COG0419	ATPase involved in DNA repair
EAE30_RS01420	COG0420	3'-5' exonuclease activity
EAE30_RS01425	COG1609	Transcriptional regulator
EAE30_RS01435	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EAE30_RS01435	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EAE30_RS01440	COG1105	Belongs to the carbohydrate kinase PfkB family
EAE30_RS01445	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EAE30_RS01445	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EAE30_RS01445	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
EAE30_RS01455	COG0189	ligase activity
EAE30_RS01455	COG4067	protein conserved in archaea
EAE30_RS01465	COG0673	inositol 2-dehydrogenase activity
EAE30_RS01475	COG3509	depolymerase
EAE30_RS01475	COG3693	PFAM glycoside hydrolase, family 10
EAE30_RS01495	COG3693	PFAM glycoside hydrolase, family 10
EAE30_RS01500	COG5297	Belongs to the glycosyl hydrolase family 6
EAE30_RS01510	COG2095	MarC family integral membrane protein
EAE30_RS01520	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EAE30_RS01535	COG0583	DNA-binding transcription factor activity
EAE30_RS01540	COG0602	queuosine metabolic process
EAE30_RS01545	COG1328	CTP reductase activity
EAE30_RS01560	COG0724	RNA recognition motif
EAE30_RS01575	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
EAE30_RS01580	COG1477	protein flavinylation
EAE30_RS01615	COG2501	S4 domain
EAE30_RS01625	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
EAE30_RS01630	COG0737	Belongs to the 5'-nucleotidase family
EAE30_RS01635	COG3385	transposase activity
EAE30_RS01645	COG0583	DNA-binding transcription factor activity
EAE30_RS01650	COG0513	Belongs to the DEAD box helicase family
EAE30_RS01655	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
EAE30_RS01710	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EAE30_RS01750	COG0561	phosphatase activity
EAE30_RS01760	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EAE30_RS01760	COG4191	Histidine kinase
EAE30_RS01770	COG1716	ATPase activity
EAE30_RS01770	COG5001	Diguanylate cyclase
EAE30_RS01775	COG5002	protein histidine kinase activity
EAE30_RS01785	COG2201	protein-glutamate methylesterase activity
EAE30_RS01795	COG1115	amino acid carrier protein
EAE30_RS01800	COG0312	modulator of DNA gyrase
EAE30_RS01805	COG0312	modulator of DNA gyrase
EAE30_RS01810	COG1757	Na H antiporter
EAE30_RS01820	COG1064	alcohol dehydrogenase
EAE30_RS01830	COG1247	-acetyltransferase
EAE30_RS01850	COG0601	transmembrane transport
EAE30_RS01855	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EAE30_RS01860	COG0444	Belongs to the ABC transporter superfamily
EAE30_RS01870	COG0477	Major facilitator Superfamily
EAE30_RS01885	COG0246	Mannitol dehydrogenase
EAE30_RS01910	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EAE30_RS01920	COG4580	involved in the transport of maltose and maltodextrins
EAE30_RS01935	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
EAE30_RS01985	COG0840	transmembrane signaling receptor activity
EAE30_RS02025	COG0513	Belongs to the DEAD box helicase family
EAE30_RS02030	COG1234	tRNA 3'-trailer cleavage
EAE30_RS02050	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EAE30_RS02055	COG4604	ABC transporter, ATP-binding protein
EAE30_RS02060	COG4605	iron ion homeostasis
EAE30_RS02065	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EAE30_RS02125	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EAE30_RS02140	COG0745	RESPONSE REGULATOR receiver
EAE30_RS02150	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EAE30_RS02170	COG4989	oxidoreductase activity
EAE30_RS02175	COG3047	cAMP biosynthetic process
EAE30_RS02190	COG1278	Cold shock
EAE30_RS02205	COG3181	Tripartite tricarboxylate transporter family receptor
EAE30_RS02220	COG3290	protein histidine kinase activity
EAE30_RS02225	COG4565	transcriptional regulatory protein
EAE30_RS02235	COG1120	ATPase activity
EAE30_RS02240	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EAE30_RS02245	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EAE30_RS02255	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EAE30_RS02300	COG3385	transposase activity
EAE30_RS02305	COG1063	alcohol dehydrogenase
EAE30_RS02310	COG0156	8-amino-7-oxononanoate synthase activity
EAE30_RS02315	COG1012	belongs to the aldehyde dehydrogenase family
EAE30_RS02320	COG3284	Transcriptional regulator
EAE30_RS02335	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EAE30_RS02345	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EAE30_RS02350	COG0363	glucosamine-6-phosphate deaminase activity
EAE30_RS02360	COG0840	transmembrane signaling receptor activity
EAE30_RS02410	COG3217	Mosc domain protein beta barrel domain protein
EAE30_RS02410	COG0633	Ferredoxin
EAE30_RS02415	COG0418	dihydroorotase activity
EAE30_RS02420	COG2354	Protein conserved in bacteria
EAE30_RS02440	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EAE30_RS02495	COG2755	lipolytic protein G-D-S-L family
EAE30_RS02495	COG0657	acetylesterase activity
EAE30_RS02535	COG3647	Membrane
EAE30_RS02575	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EAE30_RS02585	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EAE30_RS02630	COG1126	abc transporter atp-binding protein
EAE30_RS02635	COG0765	amino acid transport
EAE30_RS02640	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EAE30_RS02645	COG0010	Belongs to the arginase family
EAE30_RS02660	COG4175	Glycine betaine
EAE30_RS02665	COG4176	ABC-type proline glycine betaine transport system permease component
EAE30_RS02670	COG2113	Glycine betaine
EAE30_RS02680	COG2239	Acts as a magnesium transporter
EAE30_RS02685	COG0527	aspartate kinase activity
EAE30_RS02690	COG0662	Cupin 2, conserved barrel domain protein
EAE30_RS02695	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EAE30_RS02700	COG0456	acetyltransferase
EAE30_RS02705	COG0642	Histidine kinase
EAE30_RS02720	COG1028	Short-chain dehydrogenase reductase Sdr
EAE30_RS02730	COG1022	Amp-dependent synthetase and ligase
EAE30_RS02745	COG0583	DNA-binding transcription factor activity
EAE30_RS02755	COG0110	maltose O-acetyltransferase activity
EAE30_RS02760	COG1765	OsmC-like protein
EAE30_RS02765	COG3932	Exopolysaccharide synthesis, ExoD
EAE30_RS02780	COG2223	nitrite transmembrane transporter activity
EAE30_RS02785	COG3279	Response regulator of the LytR AlgR family
EAE30_RS02790	COG3275	phosphorelay sensor kinase activity
EAE30_RS02805	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EAE30_RS02810	COG3661	Belongs to the glycosyl hydrolase 67 family
EAE30_RS02815	COG0531	amino acid
EAE30_RS02830	COG1484	DNA-dependent DNA replication
EAE30_RS02835	COG4584	PFAM Integrase catalytic
EAE30_RS02860	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EAE30_RS02870	COG3152	Membrane
EAE30_RS02910	COG0625	glutathione transferase activity
EAE30_RS02915	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EAE30_RS02935	COG3180	Ammonia monooxygenase
EAE30_RS02955	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EAE30_RS02960	COG4208	sulfate ABC transporter
EAE30_RS02965	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
EAE30_RS02970	COG4150	thiosulfate binding
EAE30_RS02980	COG0656	L-ascorbic acid biosynthetic process
EAE30_RS02985	COG3681	Belongs to the UPF0597 family
EAE30_RS02990	COG0488	(ABC) transporter
EAE30_RS03010	COG0444	Belongs to the ABC transporter superfamily
EAE30_RS03025	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EAE30_RS03030	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
EAE30_RS03040	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
EAE30_RS03045	COG4139	cobalamin transport
EAE30_RS03065	COG1175	transmembrane transport
EAE30_RS03070	COG0395	ABC-type sugar transport system, permease component
EAE30_RS03085	COG1120	ATPase activity
EAE30_RS03090	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EAE30_RS03095	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EAE30_RS03100	COG4264	IucA IucC family
EAE30_RS03135	COG0569	domain protein
EAE30_RS03135	COG0189	ligase activity
EAE30_RS03145	COG0516	GMP reductase activity
EAE30_RS03150	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EAE30_RS03155	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EAE30_RS03155	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EAE30_RS03180	COG3036	rescue of stalled ribosome
EAE30_RS03185	COG1278	Cold shock
EAE30_RS03200	COG3507	Belongs to the glycosyl hydrolase 43 family
EAE30_RS03215	COG0714	Associated with various cellular activities
EAE30_RS03235	COG2304	oxidoreductase activity
EAE30_RS03255	COG0583	DNA-binding transcription factor activity
EAE30_RS03260	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EAE30_RS03265	COG3002	Belongs to the UPF0753 family
EAE30_RS03270	COG0009	L-threonylcarbamoyladenylate synthase
EAE30_RS03275	COG1012	belongs to the aldehyde dehydrogenase family
EAE30_RS03285	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EAE30_RS03290	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EAE30_RS03300	COG3852	Histidine kinase
EAE30_RS03325	COG2822	iron ion transport
EAE30_RS03345	COG3530	Putative quorum-sensing-regulated virulence factor
EAE30_RS03360	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EAE30_RS03365	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EAE30_RS03370	COG1902	pentaerythritol trinitrate reductase activity
EAE30_RS03390	COG0179	Fumarylacetoacetate (FAA) hydrolase
EAE30_RS03395	COG1846	Transcriptional regulator
EAE30_RS03400	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
EAE30_RS03410	COG0739	heme binding
EAE30_RS03420	COG3314	Sporulation integral membrane protein YlbJ
EAE30_RS03425	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EAE30_RS03430	COG1764	response to oxidative stress
EAE30_RS03440	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
EAE30_RS03455	COG0513	Belongs to the DEAD box helicase family
EAE30_RS03465	COG1388	LysM domain
EAE30_RS03465	COG1376	ErfK ybiS ycfS ynhG family protein
EAE30_RS03470	COG0415	Belongs to the DNA photolyase family
EAE30_RS03475	COG0789	Transcriptional regulator
EAE30_RS03480	COG3272	Protein of unknown function (DUF1722)
EAE30_RS03525	COG0463	Glycosyl transferase, family 2
EAE30_RS03550	COG0671	phosphoesterase, PA-phosphatase related
EAE30_RS03570	COG1131	(ABC) transporter
EAE30_RS03575	COG2188	Transcriptional regulator
EAE30_RS03580	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
EAE30_RS03585	COG0471	metal ion transport
EAE30_RS03615	COG3501	Rhs element vgr protein
EAE30_RS03635	COG4104	PAAR repeat-containing protein
EAE30_RS03640	COG3501	Rhs element vgr protein
EAE30_RS03650	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EAE30_RS03655	COG1640	4-alpha-glucanotransferase
EAE30_RS03660	COG0058	SHG alpha-glucan phosphorylase activity
EAE30_RS03675	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EAE30_RS03680	COG1845	cytochrome c oxidase, subunit III
EAE30_RS03685	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EAE30_RS03690	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EAE30_RS03695	COG0217	transcriptional regulatory protein
EAE30_RS03725	COG1444	tRNA N-acetyltransferase activity
EAE30_RS03775	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EAE30_RS03800	COG0739	heme binding
EAE30_RS03810	COG0363	glucosamine-6-phosphate deaminase activity
EAE30_RS03830	COG2259	Doxx family
EAE30_RS03840	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EAE30_RS03845	COG0028	Belongs to the TPP enzyme family
EAE30_RS03855	COG2200	EAL domain
EAE30_RS03915	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EAE30_RS03920	COG0673	inositol 2-dehydrogenase activity
EAE30_RS03925	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EAE30_RS03935	COG2130	NADP-dependent
EAE30_RS03940	COG1309	transcriptional regulator
EAE30_RS03945	COG0564	pseudouridine synthase activity
EAE30_RS04005	COG3829	transcription factor binding
EAE30_RS04030	COG3501	Rhs element vgr protein
EAE30_RS04045	COG3209	COG3209 Rhs family protein
EAE30_RS04055	COG3501	Rhs element vgr protein
EAE30_RS04085	COG3209	COG3209 Rhs family protein
EAE30_RS04115	COG3501	Rhs element vgr protein
EAE30_RS04120	COG4104	PAAR repeat-containing protein
EAE30_RS04155	COG2824	Alkylphosphonate utilization operon protein PhnA
EAE30_RS04160	COG0800	Aldolase
EAE30_RS04165	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EAE30_RS04175	COG1917	Cupin 2, conserved barrel domain protein
EAE30_RS04185	COG1028	Short-chain dehydrogenase reductase Sdr
EAE30_RS04195	COG0517	IMP dehydrogenase activity
EAE30_RS04210	COG0583	DNA-binding transcription factor activity
EAE30_RS04225	COG0328	RNA-DNA hybrid ribonuclease activity
EAE30_RS04225	COG3341	Caulimovirus viroplasmin
EAE30_RS04230	COG4221	oxidoreductase activity
EAE30_RS04245	COG0583	DNA-binding transcription factor activity
EAE30_RS04250	COG0604	alcohol dehydrogenase
EAE30_RS04250	COG3321	synthase
EAE30_RS04290	COG2610	gluconate transmembrane transporter activity
EAE30_RS04295	COG1929	Belongs to the glycerate kinase type-1 family
EAE30_RS04305	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EAE30_RS04315	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EAE30_RS04325	COG1473	amidohydrolase
EAE30_RS04330	COG0583	DNA-binding transcription factor activity
EAE30_RS04345	COG1846	Transcriptional regulator
EAE30_RS04365	COG3608	succinylglutamate desuccinylase aspartoacylase
EAE30_RS04375	COG1794	racemase activity, acting on amino acids and derivatives
EAE30_RS04395	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EAE30_RS04400	COG2207	Transcriptional regulator
EAE30_RS04425	COG2205	protein histidine kinase activity
EAE30_RS04430	COG0745	RESPONSE REGULATOR receiver
EAE30_RS04435	COG0569	domain protein
EAE30_RS04440	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EAE30_RS04445	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EAE30_RS04455	COG1070	Carbohydrate kinase
EAE30_RS04465	COG2390	Transcriptional regulator
EAE30_RS04495	COG2433	Pfam Transposase IS66
EAE30_RS04545	COG0583	DNA-binding transcription factor activity
EAE30_RS04550	COG0668	transmembrane transport
EAE30_RS04560	COG0513	Belongs to the DEAD box helicase family
EAE30_RS04565	COG1823	symporter activity
EAE30_RS04580	COG1566	PFAM secretion protein HlyD family protein
EAE30_RS04585	COG2814	Major facilitator Superfamily
EAE30_RS04590	COG3384	dioxygenase
EAE30_RS04610	COG1869	D-ribose catabolic process
EAE30_RS04615	COG1129	ABC transporter
EAE30_RS04620	COG1172	Belongs to the binding-protein-dependent transport system permease family
EAE30_RS04625	COG1879	ABC-type sugar transport system periplasmic component
EAE30_RS04630	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EAE30_RS04635	COG1609	Transcriptional regulator
EAE30_RS04645	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EAE30_RS04655	COG1067	ATP-dependent peptidase activity
EAE30_RS04665	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EAE30_RS04670	COG1115	amino acid carrier protein
EAE30_RS04680	COG4948	Mandelate Racemase Muconate Lactonizing
EAE30_RS04690	COG0668	transmembrane transport
EAE30_RS04695	COG0569	domain protein
EAE30_RS04700	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EAE30_RS04710	COG1741	Belongs to the pirin family
EAE30_RS04730	COG0697	spore germination
EAE30_RS04740	COG0835	chemotaxis
EAE30_RS04740	COG0784	Response regulator, receiver
EAE30_RS04745	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EAE30_RS04765	COG4584	PFAM Integrase catalytic
EAE30_RS04770	COG1484	DNA-dependent DNA replication
EAE30_RS04800	COG2433	Pfam Transposase IS66
EAE30_RS04845	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EAE30_RS04845	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EAE30_RS04850	COG0509	glycine decarboxylation via glycine cleavage system
EAE30_RS04860	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EAE30_RS04875	COG2203	Gaf domain
EAE30_RS04875	COG5001	Diguanylate cyclase
EAE30_RS04875	COG3706	GGDEF domain
EAE30_RS04875	COG4251	negative regulation of phosphorylation
EAE30_RS04890	COG0546	phosphoglycolate phosphatase activity
EAE30_RS04910	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EAE30_RS04920	COG4181	ATPase activity
EAE30_RS04925	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
EAE30_RS04935	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EAE30_RS04950	COG0814	amino acid
EAE30_RS04955	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
EAE30_RS04960	COG0513	Belongs to the DEAD box helicase family
EAE30_RS04980	COG4628	conserved protein (DUF2132)
EAE30_RS04985	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
EAE30_RS04990	COG1121	(ABC) transporter
EAE30_RS04995	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EAE30_RS05000	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EAE30_RS05005	COG1733	regulation of RNA biosynthetic process
EAE30_RS05010	COG0693	protein deglycase activity
EAE30_RS05015	COG3507	Belongs to the glycosyl hydrolase 43 family
EAE30_RS05065	COG4584	PFAM Integrase catalytic
EAE30_RS05075	COG0592	DNA-directed DNA polymerase activity
EAE30_RS05080	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EAE30_RS05085	COG0187	DNA topoisomerase II activity
EAE30_RS05090	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EAE30_RS05100	COG0071	Belongs to the small heat shock protein (HSP20) family
EAE30_RS05105	COG3977	Valine--pyruvate aminotransferase
EAE30_RS05110	COG0751	glycine-tRNA ligase activity
EAE30_RS05115	COG0752	glycyl-tRNA synthetase alpha subunit
EAE30_RS05120	COG2119	membrane
EAE30_RS05145	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EAE30_RS05150	COG3978	acetolactate synthase activity
EAE30_RS05205	COG0606	chelatase, subunit chli
EAE30_RS05210	COG0204	Acyl-transferase
EAE30_RS05215	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EAE30_RS05220	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EAE30_RS05225	COG3084	Protein conserved in bacteria
EAE30_RS05240	COG1272	protein, Hemolysin III
EAE30_RS05250	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EAE30_RS05255	COG0569	domain protein
EAE30_RS05260	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EAE30_RS05260	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EAE30_RS05275	COG0758	DNA mediated transformation
EAE30_RS05280	COG2922	Belongs to the Smg family
EAE30_RS05285	COG0551	DNA topoisomerase type I activity
EAE30_RS05295	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EAE30_RS05300	COG0009	L-threonylcarbamoyladenylate synthase
EAE30_RS05305	COG0408	coproporphyrinogen oxidase activity
EAE30_RS05320	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EAE30_RS05385	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EAE30_RS05390	COG0583	DNA-binding transcription factor activity
EAE30_RS05395	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EAE30_RS05400	COG2960	long-chain fatty acid transporting porin activity
EAE30_RS05405	COG0210	DNA helicase
EAE30_RS05440	COG0747	negative chemotaxis
EAE30_RS05445	COG0601	transmembrane transport
EAE30_RS05450	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EAE30_RS05465	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EAE30_RS05470	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EAE30_RS05485	COG1597	lipid kinase activity
EAE30_RS05500	COG2204	response regulator
EAE30_RS05505	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EAE30_RS05510	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
EAE30_RS05515	COG0339	signal peptide processing
EAE30_RS05525	COG0210	DNA helicase
EAE30_RS05535	COG0514	ATP-dependent DNA helicase (RecQ)
EAE30_RS05550	COG1368	sulfuric ester hydrolase activity
EAE30_RS05555	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EAE30_RS05575	COG1196	nuclear chromosome segregation
EAE30_RS05610	COG2003	Belongs to the UPF0758 family
EAE30_RS05615	COG0328	RNA-DNA hybrid ribonuclease activity
EAE30_RS05645	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EAE30_RS05660	COG0582	viral genome integration into host DNA
EAE30_RS05665	COG1561	YicC-like family, N-terminal region
EAE30_RS05670	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EAE30_RS05675	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EAE30_RS05680	COG1560	Kdo2-lipid A biosynthetic process
EAE30_RS05685	COG1309	transcriptional regulator
EAE30_RS05690	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EAE30_RS05695	COG2003	Belongs to the UPF0758 family
EAE30_RS05700	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EAE30_RS05705	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EAE30_RS05720	COG1442	glycosyl transferase family 8
EAE30_RS05730	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EAE30_RS05735	COG0297	glycogen (starch) synthase activity
EAE30_RS05740	COG0463	Glycosyl transferase, family 2
EAE30_RS05745	COG0859	PFAM glycosyl transferase family 9
EAE30_RS05750	COG3642	lipopolysaccharide core region biosynthetic process
EAE30_RS05755	COG1519	Transferase
EAE30_RS05765	COG0438	transferase activity, transferring glycosyl groups
EAE30_RS05775	COG0859	PFAM glycosyl transferase family 9
EAE30_RS05780	COG1560	Kdo2-lipid A biosynthetic process
EAE30_RS05875	COG1215	transferase activity, transferring glycosyl groups
EAE30_RS05880	COG3335	DDE superfamily endonuclease
EAE30_RS05905	COG2433	Pfam Transposase IS66
EAE30_RS05930	COG1566	PFAM secretion protein HlyD family protein
EAE30_RS05940	COG1573	uracil-dna glycosylase
EAE30_RS05950	COG0776	regulation of translation
EAE30_RS05960	COG0151	Belongs to the GarS family
EAE30_RS05965	COG0138	bifunctional purine biosynthesis protein purh
EAE30_RS05975	COG2814	Major facilitator Superfamily
EAE30_RS05980	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EAE30_RS06035	COG0232	Belongs to the dGTPase family. Type 2 subfamily
EAE30_RS06045	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
EAE30_RS06055	COG2264	protein methyltransferase activity
EAE30_RS06060	COG4145	pantothenate transmembrane transporter activity
EAE30_RS06070	COG0439	Biotin carboxylase
EAE30_RS06075	COG0511	ligase activity, forming carbon-carbon bonds
EAE30_RS06080	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EAE30_RS06085	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EAE30_RS06090	COG2814	Major facilitator Superfamily
EAE30_RS06095	COG2205	protein histidine kinase activity
EAE30_RS06095	COG0784	Response regulator, receiver
EAE30_RS06095	COG2198	Histidine kinase
EAE30_RS06100	COG0248	Ppx GppA phosphatase
EAE30_RS06105	COG0513	Belongs to the DEAD box helicase family
EAE30_RS06110	COG3118	belongs to the thioredoxin family
EAE30_RS06125	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
EAE30_RS06170	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EAE30_RS06180	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EAE30_RS06190	COG1072	(Pantothenic acid kinase))
EAE30_RS06220	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EAE30_RS06225	COG0250	Participates in transcription elongation, termination and antitermination
EAE30_RS06230	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EAE30_RS06235	COG0081	regulation of translation
EAE30_RS06240	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EAE30_RS06245	COG0222	ribosome binding
EAE30_RS06250	COG0085	RNA polymerase activity
EAE30_RS06255	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EAE30_RS06260	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
EAE30_RS06265	COG2816	NAD+ diphosphatase activity
EAE30_RS06270	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EAE30_RS06285	COG4942	peptidase
EAE30_RS06290	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EAE30_RS06295	COG0688	phosphatidylethanolamine metabolic process
EAE30_RS06300	COG1162	GTPase activity
EAE30_RS06305	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
EAE30_RS06360	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EAE30_RS06365	COG0802	atpase or kinase
EAE30_RS06375	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EAE30_RS06380	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EAE30_RS06385	COG1923	regulation of RNA biosynthetic process
EAE30_RS06390	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EAE30_RS06395	COG0330	HflC and HflK could
EAE30_RS06400	COG0330	HflC and HflK could
EAE30_RS06415	COG0545	Peptidyl-prolyl cis-trans isomerase
EAE30_RS06425	COG2964	Protein conserved in bacteria
EAE30_RS06430	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
EAE30_RS06435	COG2923	Belongs to the DsrF TusC family
EAE30_RS06455	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EAE30_RS06465	COG0360	Binds together with S18 to 16S ribosomal RNA
EAE30_RS06470	COG2965	DNA replication, synthesis of RNA primer
EAE30_RS06480	COG0359	binds to the 23S rRNA
EAE30_RS06495	COG0432	Pfam Uncharacterised protein family UPF0047
EAE30_RS06510	COG0735	belongs to the Fur family
EAE30_RS06515	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EAE30_RS06535	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EAE30_RS06545	COG0175	sulfate reduction
EAE30_RS06600	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
EAE30_RS06610	COG0527	aspartate kinase activity
EAE30_RS06620	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EAE30_RS06630	COG2197	response regulator
EAE30_RS06635	COG0629	single-stranded DNA binding
EAE30_RS06640	COG4974	Belongs to the 'phage' integrase family
EAE30_RS06650	COG4584	PFAM Integrase catalytic
EAE30_RS06655	COG1484	DNA-dependent DNA replication
EAE30_RS06690	COG0443	Heat shock 70 kDa protein
EAE30_RS06710	COG3550	peptidyl-serine autophosphorylation
EAE30_RS06735	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EAE30_RS06745	COG2200	EAL domain
EAE30_RS06745	COG2199	diguanylate cyclase activity
EAE30_RS06755	COG1077	Cell shape determining protein MreB Mrl
EAE30_RS06760	COG1792	Involved in formation and maintenance of cell shape
EAE30_RS06765	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
EAE30_RS06770	COG0424	maF-like protein
EAE30_RS06775	COG1530	ribonuclease E activity
EAE30_RS06780	COG3164	Protein of unknown function
EAE30_RS06785	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EAE30_RS06790	COG0312	modulator of DNA gyrase
EAE30_RS06795	COG2235	arginine
EAE30_RS06805	COG3385	transposase activity
EAE30_RS06830	COG1438	arginine binding
EAE30_RS06840	COG0142	geranyltranstransferase activity
EAE30_RS06845	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EAE30_RS06850	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EAE30_RS06855	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EAE30_RS06860	COG2966	Psort location CytoplasmicMembrane, score
EAE30_RS06865	COG3610	response to peptide
EAE30_RS06875	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EAE30_RS06880	COG2967	ApaG domain
EAE30_RS06885	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EAE30_RS06890	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EAE30_RS06895	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EAE30_RS06900	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
EAE30_RS06905	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
EAE30_RS06955	COG0741	lytic transglycosylase activity
EAE30_RS06960	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
EAE30_RS06970	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EAE30_RS06975	COG2066	Belongs to the glutaminase family
EAE30_RS06980	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EAE30_RS06985	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EAE30_RS06990	COG0762	integral membrane protein
EAE30_RS06995	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EAE30_RS07000	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EAE30_RS07010	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EAE30_RS07015	COG1678	Uncharacterized ACR, COG1678
EAE30_RS07020	COG0189	ligase activity
EAE30_RS07025	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EAE30_RS07035	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EAE30_RS07040	COG0583	DNA-binding transcription factor activity
EAE30_RS07045	COG4771	TonB-dependent receptor
EAE30_RS07050	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EAE30_RS07055	COG0126	phosphoglycerate kinase activity
EAE30_RS07065	COG0668	transmembrane transport
EAE30_RS07075	COG0469	pyruvate kinase activity
EAE30_RS07080	COG1349	DNA-binding transcription factor activity
EAE30_RS07100	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EAE30_RS07130	COG1201	RNA secondary structure unwinding
EAE30_RS07195	COG2855	membrane
EAE30_RS07200	COG0583	DNA-binding transcription factor activity
EAE30_RS07225	COG1910	domain protein
EAE30_RS07260	COG2433	Pfam Transposase IS66
EAE30_RS07280	COG1846	Transcriptional regulator
EAE30_RS07290	COG0697	spore germination
EAE30_RS07295	COG0583	DNA-binding transcription factor activity
EAE30_RS07305	COG0583	DNA-binding transcription factor activity
EAE30_RS07310	COG4774	siderophore transport
EAE30_RS07330	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EAE30_RS07335	COG2084	Dehydrogenase
EAE30_RS07360	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EAE30_RS07365	COG0840	transmembrane signaling receptor activity
EAE30_RS07375	COG2723	6-phospho-beta-galactosidase activity
EAE30_RS07390	COG3037	sugar-specific permease SgaT UlaA
EAE30_RS07395	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EAE30_RS07415	COG2211	Major facilitator Superfamily
EAE30_RS07420	COG2207	Transcriptional regulator
EAE30_RS07440	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EAE30_RS07445	COG2433	Pfam Transposase IS66
EAE30_RS07520	COG1610	YqeY-like protein
EAE30_RS07525	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EAE30_RS07535	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EAE30_RS07540	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
EAE30_RS07545	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EAE30_RS07550	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EAE30_RS07555	COG1968	undecaprenyl-diphosphatase activity
EAE30_RS07560	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
EAE30_RS07565	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EAE30_RS07575	COG0585	pseudouridine synthase activity
EAE30_RS07580	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
EAE30_RS07585	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EAE30_RS07590	COG1388	LysM domain
EAE30_RS07590	COG4942	peptidase
EAE30_RS07595	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EAE30_RS07600	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EAE30_RS07605	COG1546	Belongs to the CinA family
EAE30_RS07610	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EAE30_RS07615	COG2137	regulation of response to DNA damage stimulus
EAE30_RS07620	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EAE30_RS07625	COG0527	aspartate kinase activity
EAE30_RS07680	COG1238	metal cluster binding
EAE30_RS07685	COG0612	Peptidase, M16
EAE30_RS07690	COG2918	glutathione biosynthetic process
EAE30_RS07700	COG1854	S-ribosylhomocysteine lyase activity
EAE30_RS07705	COG4536	flavin adenine dinucleotide binding
EAE30_RS07710	COG4137	Cytochrome C assembly protein
EAE30_RS07715	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EAE30_RS07720	COG0228	four-way junction DNA binding
EAE30_RS07725	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EAE30_RS07730	COG0336	Belongs to the RNA methyltransferase TrmD family
EAE30_RS07740	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EAE30_RS07755	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
EAE30_RS07760	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EAE30_RS07765	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EAE30_RS07770	COG0625	glutathione transferase activity
EAE30_RS07775	COG2969	positive regulation of protein catabolic process
EAE30_RS07780	COG3385	transposase activity
EAE30_RS07785	COG2823	Periplasmic or secreted lipoprotein
EAE30_RS07790	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
EAE30_RS07795	COG0792	nuclease activity
EAE30_RS07800	COG3107	peptidoglycan biosynthetic process
EAE30_RS07805	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EAE30_RS07815	COG0275	rRNA processing
EAE30_RS07820	COG3116	cell division
EAE30_RS07825	COG0768	penicillin binding
EAE30_RS07830	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EAE30_RS07835	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EAE30_RS07845	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EAE30_RS07850	COG0772	Belongs to the SEDS family
EAE30_RS07855	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EAE30_RS07860	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EAE30_RS07865	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EAE30_RS07870	COG0849	cell division
EAE30_RS07875	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EAE30_RS07880	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
EAE30_RS07895	COG0494	nUDIX hydrolase
EAE30_RS07905	COG0505	Belongs to the CarA family
EAE30_RS07910	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EAE30_RS07915	COG0730	response to heat
EAE30_RS07920	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
EAE30_RS07925	COG2860	membrane
EAE30_RS07930	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EAE30_RS07940	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EAE30_RS07950	COG0493	'glutamate synthase
EAE30_RS07955	COG0067	glutamate synthase
EAE30_RS07955	COG0070	glutamate synthase
EAE30_RS07955	COG0069	glutamate synthase activity
EAE30_RS07965	COG0784	Response regulator, receiver
EAE30_RS07965	COG2198	Histidine kinase
EAE30_RS07965	COG5002	protein histidine kinase activity
EAE30_RS07975	COG0745	RESPONSE REGULATOR receiver
EAE30_RS07980	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EAE30_RS07995	COG0083	homoserine kinase activity
EAE30_RS08000	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EAE30_RS08005	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
EAE30_RS08010	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EAE30_RS08030	COG1115	amino acid carrier protein
EAE30_RS08045	COG3022	response to hydroperoxide
EAE30_RS08050	COG0084	hydrolase, TatD family'
EAE30_RS08055	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EAE30_RS08065	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
EAE30_RS08070	COG0813	purine-nucleoside phosphorylase activity
EAE30_RS08080	COG0560	Phosphoserine phosphatase
EAE30_RS08090	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EAE30_RS08100	COG2017	converts alpha-aldose to the beta-anomer
EAE30_RS08105	COG3385	transposase activity
EAE30_RS08120	COG2171	N-acyltransferase activity
EAE30_RS08125	COG3141	response to X-ray
EAE30_RS08135	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
EAE30_RS08140	COG1074	ATP-dependent DNA helicase activity
EAE30_RS08145	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EAE30_RS08155	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
EAE30_RS08155	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EAE30_RS08165	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
EAE30_RS08170	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EAE30_RS08175	COG2166	iron-sulfur cluster assembly
EAE30_RS08185	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EAE30_RS08190	COG0693	protein deglycase activity
EAE30_RS08195	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EAE30_RS08200	COG3248	Nucleoside-binding outer membrane protein
EAE30_RS08210	COG0477	Major facilitator Superfamily
EAE30_RS08215	COG2807	transmembrane transport
EAE30_RS08220	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EAE30_RS08235	COG0271	Belongs to the BolA IbaG family
EAE30_RS08245	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
EAE30_RS08250	COG1805	sodium ion transport
EAE30_RS08270	COG2871	sodium ion transport
EAE30_RS08275	COG1477	protein flavinylation
EAE30_RS08285	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EAE30_RS08295	COG0733	neurotransmitter:sodium symporter activity
EAE30_RS08310	COG0189	ligase activity
EAE30_RS08310	COG4067	protein conserved in archaea
EAE30_RS08315	COG2195	Cleaves the N-terminal amino acid of tripeptides
EAE30_RS08320	COG2252	PERMEase
EAE30_RS08325	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
EAE30_RS08330	COG1073	alpha beta
EAE30_RS08340	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EAE30_RS08345	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EAE30_RS08350	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EAE30_RS08355	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EAE30_RS08355	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EAE30_RS08375	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EAE30_RS08380	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EAE30_RS08385	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EAE30_RS08390	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
EAE30_RS08395	COG0024	Methionine aminopeptidase
EAE30_RS08405	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EAE30_RS08410	COG0528	UMP kinase activity
EAE30_RS08420	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EAE30_RS08425	COG0575	Belongs to the CDS family
EAE30_RS08430	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
EAE30_RS08435	COG0750	zinc metalloprotease
EAE30_RS08440	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EAE30_RS08445	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
EAE30_RS08450	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EAE30_RS08455	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EAE30_RS08460	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EAE30_RS08465	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EAE30_RS08475	COG0587	DNA-directed DNA polymerase activity
EAE30_RS08485	COG0037	tRNA processing
EAE30_RS08495	COG0347	Belongs to the P(II) protein family
EAE30_RS08500	COG3021	interspecies interaction between organisms
EAE30_RS08505	COG0741	lytic transglycosylase activity
EAE30_RS08505	COG1388	LysM domain
EAE30_RS08510	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EAE30_RS08515	COG2226	methyltransferase
EAE30_RS08535	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
EAE30_RS08540	COG0121	glutamine amidotransferase
EAE30_RS08545	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EAE30_RS08550	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EAE30_RS08560	COG1187	pseudouridine synthase activity
EAE30_RS08575	COG3735	TraB family
EAE30_RS08580	COG2217	Heavy metal translocating P-type atpase
EAE30_RS08580	COG2608	mercury ion transmembrane transporter activity
EAE30_RS08585	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EAE30_RS08630	COG0784	Response regulator, receiver
EAE30_RS08630	COG0835	chemotaxis
EAE30_RS08635	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EAE30_RS08640	COG1815	bacterial-type flagellum-dependent cell motility
EAE30_RS08655	COG1749	Flagellar hook protein flgE
EAE30_RS08660	COG4787	bacterial-type flagellum-dependent cell motility
EAE30_RS08670	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
EAE30_RS08675	COG1706	bacterial-type flagellum-dependent cell motility
EAE30_RS08680	COG3951	Flagellar rod assembly protein muramidase FlgJ
EAE30_RS08680	COG1705	Flagellar rod assembly protein muramidase FlgJ
EAE30_RS08695	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EAE30_RS08790	COG0193	aminoacyl-tRNA hydrolase activity
EAE30_RS08795	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EAE30_RS08800	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EAE30_RS08805	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
EAE30_RS08810	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EAE30_RS08815	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EAE30_RS08820	COG2890	protein-(glutamine-N5) methyltransferase activity
EAE30_RS08825	COG3094	Invasion gene expression up-regulator, SirB
EAE30_RS08830	COG2912	Transglutaminase-like superfamily
EAE30_RS08835	COG2877	3-deoxy-8-phosphooctulonate synthase activity
EAE30_RS08840	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EAE30_RS08860	COG1393	Belongs to the ArsC family
EAE30_RS08865	COG4783	chaperone-mediated protein folding
EAE30_RS08875	COG3385	transposase activity
EAE30_RS08880	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EAE30_RS08910	COG2433	Pfam Transposase IS66
EAE30_RS08930	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EAE30_RS08945	COG2205	protein histidine kinase activity
EAE30_RS08950	COG0745	RESPONSE REGULATOR receiver
EAE30_RS08975	COG2217	Heavy metal translocating P-type atpase
EAE30_RS08980	COG0789	Transcriptional regulator
EAE30_RS08995	COG0798	PFAM Bile acid sodium symporter
EAE30_RS09000	COG0640	Transcriptional regulator
EAE30_RS09045	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EAE30_RS09080	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EAE30_RS09085	COG2716	regulation of RNA biosynthetic process
EAE30_RS09090	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EAE30_RS09095	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
EAE30_RS09105	COG1876	peptidase activity
EAE30_RS09115	COG1393	Belongs to the ArsC family
EAE30_RS09140	COG2837	iron assimilation
EAE30_RS09145	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EAE30_RS09165	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EAE30_RS09170	COG1334	flagellar protein FlaG
EAE30_RS09175	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
EAE30_RS09185	COG1516	flagellar protein fliS
EAE30_RS09205	COG1677	Flagellar hook-basal body complex protein FliE
EAE30_RS09215	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EAE30_RS09230	COG2882	bacterial-type flagellum organization
EAE30_RS09265	COG1987	bacterial-type flagellum assembly
EAE30_RS09270	COG1684	flagellar biosynthetic protein fliR
EAE30_RS09285	COG2890	protein-(glutamine-N5) methyltransferase activity
EAE30_RS09290	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EAE30_RS09295	COG3101	peptidyl-lysine hydroxylation
EAE30_RS09315	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EAE30_RS09320	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EAE30_RS09325	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EAE30_RS09330	COG0735	belongs to the Fur family
EAE30_RS09340	COG0596	Alpha beta hydrolase
EAE30_RS09345	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
EAE30_RS09350	COG0033	Phosphoglucomutase
EAE30_RS09360	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EAE30_RS09375	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
EAE30_RS09380	COG1053	succinate dehydrogenase
EAE30_RS09390	COG0567	Dehydrogenase, E1 component
EAE30_RS09395	COG0508	dehydrogenase complex catalyzes the overall conversion of
EAE30_RS09405	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EAE30_RS09410	COG0330	HflC and HflK could
EAE30_RS09425	COG1918	ferrous iron import across plasma membrane
EAE30_RS09430	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EAE30_RS09455	COG1025	Belongs to the peptidase M16 family
EAE30_RS09460	COG2062	phosphohistidine phosphatase, SixA
EAE30_RS09465	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EAE30_RS09490	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
EAE30_RS09495	COG0643	Histidine kinase
EAE30_RS09495	COG0784	Response regulator, receiver
EAE30_RS09495	COG2198	Histidine kinase
EAE30_RS09500	COG2201	protein-glutamate methylesterase activity
EAE30_RS09505	COG1192	Involved in chromosome partitioning
EAE30_RS09515	COG0835	chemotaxis
EAE30_RS09525	COG4133	protoheme IX ABC transporter activity
EAE30_RS09530	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EAE30_RS09535	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EAE30_RS09545	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
EAE30_RS09550	COG1138	Cytochrome C-type biogenesis protein
EAE30_RS09555	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EAE30_RS09560	COG4235	cytochrome complex assembly
EAE30_RS09560	COG3088	subunit of a heme lyase
EAE30_RS09575	COG1028	Short-chain dehydrogenase reductase Sdr
EAE30_RS09590	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EAE30_RS09595	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EAE30_RS09620	COG1294	oxidase, subunit
EAE30_RS09625	COG1271	oxidase subunit
EAE30_RS09630	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EAE30_RS09635	COG0384	phenazine biosynthesis protein PhzF
EAE30_RS09665	COG3693	PFAM glycoside hydrolase, family 10
EAE30_RS09675	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EAE30_RS09680	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EAE30_RS09685	COG1012	belongs to the aldehyde dehydrogenase family
EAE30_RS09690	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EAE30_RS09700	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
EAE30_RS09715	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EAE30_RS09720	COG1278	Cold shock
EAE30_RS09725	COG4584	PFAM Integrase catalytic
EAE30_RS09730	COG1484	DNA-dependent DNA replication
EAE30_RS09760	COG3082	Protein of unknown function (DUF1414)
EAE30_RS09770	COG1757	Na H antiporter
EAE30_RS09775	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EAE30_RS09780	COG2095	MarC family integral membrane protein
EAE30_RS09785	COG1454	alcohol dehydrogenase
EAE30_RS09785	COG1012	belongs to the aldehyde dehydrogenase family
EAE30_RS09790	COG0659	secondary active sulfate transmembrane transporter activity
EAE30_RS09795	COG3385	transposase activity
EAE30_RS09800	COG1530	ribonuclease E activity
EAE30_RS09805	COG0564	pseudouridine synthase activity
EAE30_RS09810	COG0424	maF-like protein
EAE30_RS09815	COG1399	metal-binding, possibly nucleic acid-binding protein
EAE30_RS09830	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EAE30_RS09845	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EAE30_RS09855	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EAE30_RS09860	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EAE30_RS09865	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EAE30_RS09870	COG0470	DNA polymerase III
EAE30_RS09875	COG0084	hydrolase, TatD family'
EAE30_RS09880	COG2190	(PTS) system
EAE30_RS09880	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EAE30_RS09880	COG1263	PTS System
EAE30_RS09900	COG0733	neurotransmitter:sodium symporter activity
EAE30_RS09910	COG4667	esterase of the alpha-beta hydrolase superfamily
EAE30_RS09915	COG0469	pyruvate kinase activity
EAE30_RS09920	COG1940	carbohydrate kinase activity
EAE30_RS09925	COG0784	Response regulator, receiver
EAE30_RS09925	COG0835	chemotaxis
EAE30_RS09955	COG0604	alcohol dehydrogenase
EAE30_RS09960	COG1764	response to oxidative stress
EAE30_RS09965	COG3046	protein related to deoxyribodipyrimidine photolyase
EAE30_RS10000	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EAE30_RS10015	COG2207	Transcriptional regulator
EAE30_RS10040	COG0583	DNA-binding transcription factor activity
EAE30_RS10045	COG0587	DNA-directed DNA polymerase activity
EAE30_RS10065	COG1028	Short-chain dehydrogenase reductase Sdr
EAE30_RS10070	COG0616	signal peptide processing
EAE30_RS10075	COG3477	response to acidic pH
EAE30_RS10140	COG0346	lactoylglutathione lyase activity
EAE30_RS10215	COG0232	Belongs to the dGTPase family. Type 2 subfamily
EAE30_RS10220	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
EAE30_RS10225	COG0436	Aminotransferase
EAE30_RS10230	COG1169	isochorismate synthase
EAE30_RS10235	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EAE30_RS10240	COG0596	Alpha beta hydrolase
EAE30_RS10260	COG2855	membrane
EAE30_RS10265	COG2814	Major facilitator Superfamily
EAE30_RS10280	COG3385	transposase activity
EAE30_RS10290	COG1522	sequence-specific DNA binding
EAE30_RS10295	COG1946	Acyl-CoA thioesterase
EAE30_RS10330	COG0471	metal ion transport
EAE30_RS10380	COG3700	Belongs to the class B bacterial acid phosphatase family
EAE30_RS10385	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EAE30_RS10390	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EAE30_RS10395	COG1349	DNA-binding transcription factor activity
EAE30_RS10400	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EAE30_RS10405	COG1469	GTP cyclohydrolase I activity
EAE30_RS10420	COG1902	pentaerythritol trinitrate reductase activity
EAE30_RS10425	COG0579	oxidoreductase
EAE30_RS10440	COG3300	MHYT domain
EAE30_RS10440	COG5001	Diguanylate cyclase
EAE30_RS10455	COG1846	Transcriptional regulator
EAE30_RS10460	COG1914	H( )-stimulated, divalent metal cation uptake system
EAE30_RS10465	COG1321	iron dependent repressor
EAE30_RS10475	COG3152	Membrane
EAE30_RS10480	COG2211	Major facilitator Superfamily
EAE30_RS10485	COG3250	beta-galactosidase activity
EAE30_RS10495	COG2866	Carboxypeptidase
EAE30_RS10510	COG3706	GGDEF domain
EAE30_RS10515	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EAE30_RS10530	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EAE30_RS10535	COG0515	serine threonine protein kinase
EAE30_RS10540	COG1522	sequence-specific DNA binding
EAE30_RS10555	COG2731	YhcH YjgK YiaL family protein
EAE30_RS10570	COG0243	molybdopterin cofactor binding
EAE30_RS10575	COG0437	4 iron, 4 sulfur cluster binding
EAE30_RS10580	COG3302	dmso reductase anchor subunit
EAE30_RS10585	COG1054	Belongs to the UPF0176 family
EAE30_RS10625	COG3385	transposase activity
EAE30_RS10630	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EAE30_RS10635	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EAE30_RS10640	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
EAE30_RS10645	COG0386	Belongs to the glutathione peroxidase family
EAE30_RS10655	COG1609	Transcriptional regulator
EAE30_RS10660	COG2723	6-phospho-beta-galactosidase activity
EAE30_RS10670	COG0745	RESPONSE REGULATOR receiver
EAE30_RS10675	COG2205	protein histidine kinase activity
EAE30_RS10680	COG1263	PTS System
EAE30_RS10680	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EAE30_RS10690	COG1621	beta-fructofuranosidase activity
EAE30_RS10700	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EAE30_RS10715	COG0601	transmembrane transport
EAE30_RS10720	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EAE30_RS10725	COG0444	Belongs to the ABC transporter superfamily
EAE30_RS10735	COG0435	Glutathione S-transferase
EAE30_RS10745	COG0857	belongs to the CobB CobQ family
EAE30_RS10745	COG0280	phosphate acetyltransferase
EAE30_RS10750	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EAE30_RS10755	COG3092	negative regulation of chromosome organization
EAE30_RS10765	COG4120	Belongs to the binding-protein-dependent transport system permease family
EAE30_RS10770	COG1122	ATPase activity
EAE30_RS10780	COG0653	protein targeting
EAE30_RS10785	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EAE30_RS10790	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EAE30_RS10795	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EAE30_RS10800	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
EAE30_RS10810	COG0501	Belongs to the peptidase M48B family
EAE30_RS10820	COG1028	Short-chain dehydrogenase reductase Sdr
EAE30_RS10825	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EAE30_RS10835	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EAE30_RS10860	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EAE30_RS10865	COG2915	High frequency lysogenization protein hflD homolog
EAE30_RS10870	COG0482	sulfurtransferase activity
EAE30_RS10875	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EAE30_RS10885	COG1757	Na H antiporter
EAE30_RS10890	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EAE30_RS10895	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EAE30_RS10900	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EAE30_RS10905	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EAE30_RS10905	COG0131	Imidazoleglycerol-phosphate dehydratase
EAE30_RS10910	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EAE30_RS10915	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EAE30_RS10920	COG0107	imidazoleglycerol-phosphate synthase activity
EAE30_RS10925	COG0140	phosphoribosyl-ATP diphosphatase activity
EAE30_RS10925	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EAE30_RS10930	COG1187	pseudouridine synthase activity
EAE30_RS10940	COG1278	Cold shock
EAE30_RS10945	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
EAE30_RS10950	COG0542	response to heat
EAE30_RS10955	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EAE30_RS10965	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
EAE30_RS10970	COG3134	Outer membrane lipoprotein
EAE30_RS10980	COG3385	transposase activity
EAE30_RS10990	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EAE30_RS10995	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EAE30_RS11000	COG0297	glycogen (starch) synthase activity
EAE30_RS11015	COG3070	regulator of competence-specific genes
EAE30_RS11020	COG1609	Transcriptional regulator
EAE30_RS11025	COG0745	RESPONSE REGULATOR receiver
EAE30_RS11030	COG1434	Gram-negative-bacterium-type cell wall biogenesis
EAE30_RS11035	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EAE30_RS11040	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
EAE30_RS11045	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
EAE30_RS11050	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
EAE30_RS11055	COG0189	ligase activity
EAE30_RS11065	COG4067	protein conserved in archaea
EAE30_RS11065	COG0189	ligase activity
EAE30_RS11070	COG0500	methyltransferase
EAE30_RS11075	COG4106	trans-aconitate 2-methyltransferase activity
EAE30_RS11085	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EAE30_RS11090	COG1435	thymidine kinase activity
EAE30_RS11105	COG2116	formate transmembrane transporter activity
EAE30_RS11115	COG4172	Belongs to the ABC transporter superfamily
EAE30_RS11125	COG4171	peptide transport system, permease
EAE30_RS11130	COG4168	peptide transport system, permease
EAE30_RS11150	COG2818	Glycosylase
EAE30_RS11155	COG0626	cystathionine gamma-synthase activity
EAE30_RS11165	COG0733	neurotransmitter:sodium symporter activity
EAE30_RS11170	COG0564	pseudouridine synthase activity
EAE30_RS11195	COG0513	Belongs to the DEAD box helicase family
EAE30_RS11250	COG3157	Type VI secretion system effector, Hcp
EAE30_RS11260	COG1203	CRISPR-associated helicase, Cas3
EAE30_RS11325	COG1337	RAMP superfamily
EAE30_RS11345	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EAE30_RS11370	COG1061	Type III restriction enzyme res subunit
EAE30_RS11375	COG1187	pseudouridine synthase activity
EAE30_RS11380	COG2814	Major facilitator Superfamily
EAE30_RS11390	COG0702	epimerase
EAE30_RS11400	COG4181	ATPase activity
EAE30_RS11415	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EAE30_RS11420	COG0840	transmembrane signaling receptor activity
EAE30_RS11435	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EAE30_RS11440	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EAE30_RS11445	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EAE30_RS11450	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EAE30_RS11465	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EAE30_RS11470	COG2989	Protein conserved in bacteria
EAE30_RS11475	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EAE30_RS11490	COG1846	Transcriptional regulator
EAE30_RS11500	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EAE30_RS11510	COG2176	DNA-directed DNA polymerase activity
EAE30_RS11520	COG3385	transposase activity
EAE30_RS11525	COG1448	Aminotransferase
EAE30_RS11530	COG0017	Asparaginyl-tRNA synthetase
EAE30_RS11535	COG1879	ABC-type sugar transport system periplasmic component
EAE30_RS11545	COG4608	Belongs to the ABC transporter superfamily
EAE30_RS11550	COG0444	Belongs to the ABC transporter superfamily
EAE30_RS11555	COG4166	transmembrane transport
EAE30_RS11560	COG4239	(ABC) transporter, permease
EAE30_RS11565	COG4174	ABC transporter (Permease)
EAE30_RS11570	COG4771	TonB-dependent receptor
EAE30_RS11585	COG0811	peptide transport
EAE30_RS11590	COG0848	biopolymer transport protein
EAE30_RS11605	COG0095	Lipoate-protein ligase
EAE30_RS11635	COG0514	ATP-dependent DNA helicase (RecQ)
EAE30_RS11645	COG0577	efflux transmembrane transporter activity
EAE30_RS11645	COG1136	(ABC) transporter
EAE30_RS11650	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EAE30_RS11655	COG1760	l-serine dehydratase
EAE30_RS11660	COG0494	nUDIX hydrolase
EAE30_RS11680	COG3106	COG3106 Predicted ATPase
EAE30_RS11695	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EAE30_RS11705	COG1301	dicarboxylic acid transport
EAE30_RS11720	COG0840	transmembrane signaling receptor activity
EAE30_RS11725	COG0584	glycerophosphoryl diester phosphodiesterase
EAE30_RS11730	COG1349	DNA-binding transcription factor activity
EAE30_RS11735	COG3842	ATPase activity
EAE30_RS11740	COG0395	ABC-type sugar transport system, permease component
EAE30_RS11750	COG1653	transport
EAE30_RS11755	COG0039	L-malate dehydrogenase activity
EAE30_RS11760	COG3040	lipid binding
EAE30_RS11770	COG0811	peptide transport
EAE30_RS11775	COG0811	peptide transport
EAE30_RS11780	COG0848	biopolymer transport protein
EAE30_RS11785	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
EAE30_RS11795	COG1793	dna ligase
EAE30_RS11810	COG0307	riboflavin synthase, alpha
EAE30_RS11815	COG3001	Fructosamine kinase
EAE30_RS11825	COG0791	NLP P60 protein
EAE30_RS11835	COG3148	PFAM DTW domain containing protein
EAE30_RS11840	COG1940	carbohydrate kinase activity
EAE30_RS11850	COG0746	molybdenum cofactor guanylyltransferase activity
EAE30_RS11855	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EAE30_RS11860	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EAE30_RS11865	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EAE30_RS11870	COG1177	transmembrane transport
EAE30_RS11875	COG1176	ABC-type spermidine putrescine transport system, permease component I
EAE30_RS11880	COG3842	ATPase activity
EAE30_RS11895	COG0037	tRNA processing
EAE30_RS11900	COG0589	response to stress
EAE30_RS11905	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EAE30_RS11935	COG3120	sequence-specific DNA binding
EAE30_RS11940	COG1067	ATP-dependent peptidase activity
EAE30_RS11945	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EAE30_RS11960	COG0488	(ABC) transporter
EAE30_RS11965	COG0116	Belongs to the methyltransferase superfamily
EAE30_RS11965	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EAE30_RS11975	COG0167	dihydroorotate dehydrogenase activity
EAE30_RS11980	COG2902	Dehydrogenase
EAE30_RS11990	COG0308	aminopeptidase N
EAE30_RS12000	COG0793	Belongs to the peptidase S41A family
EAE30_RS12005	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
EAE30_RS12010	COG1956	GAF domain-containing protein
EAE30_RS12020	COG2995	paraquat-inducible protein a
EAE30_RS12025	COG3008	intermembrane lipid transfer
EAE30_RS12050	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EAE30_RS12055	COG1666	GTP binding
EAE30_RS12065	COG1115	amino acid carrier protein
EAE30_RS12070	COG1280	lysine exporter protein (LysE YggA)
EAE30_RS12080	COG3387	PFAM Glycoside hydrolase 15-related
EAE30_RS12095	COG3501	Rhs element vgr protein
EAE30_RS12115	COG3501	Rhs element vgr protein
EAE30_RS12150	COG3501	Rhs element vgr protein
EAE30_RS12165	COG1643	Atp-dependent helicase
EAE30_RS12170	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EAE30_RS12200	COG0443	Heat shock 70 kDa protein
EAE30_RS12205	COG0443	Heat shock 70 kDa protein
EAE30_RS12240	COG0602	queuosine metabolic process
EAE30_RS12245	COG0561	phosphatase activity
EAE30_RS12255	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EAE30_RS12260	COG4597	amino acid ABC transporter
EAE30_RS12265	COG0765	amino acid transport
EAE30_RS12270	COG1126	abc transporter atp-binding protein
EAE30_RS12275	COG0670	Belongs to the BI1 family
EAE30_RS12280	COG2920	part of a sulfur-relay system
EAE30_RS12285	COG1254	Belongs to the acylphosphatase family
EAE30_RS12290	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EAE30_RS12295	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
EAE30_RS12300	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
EAE30_RS12315	COG1609	Transcriptional regulator
EAE30_RS12330	COG3842	ATPase activity
EAE30_RS12340	COG0454	-acetyltransferase
EAE30_RS12370	COG0840	transmembrane signaling receptor activity
EAE30_RS12375	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EAE30_RS12380	COG0477	Major facilitator Superfamily
EAE30_RS12415	COG0784	Response regulator, receiver
EAE30_RS12415	COG0835	chemotaxis
EAE30_RS12430	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EAE30_RS12450	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
EAE30_RS12500	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
EAE30_RS12505	COG4139	cobalamin transport
EAE30_RS12510	COG2988	succinylglutamate desuccinylase activity
EAE30_RS12520	COG0443	Heat shock 70 kDa protein
EAE30_RS12525	COG3416	Protein conserved in bacteria
EAE30_RS12540	COG2925	Exonuclease
EAE30_RS12545	COG1380	Effector of murein hydrolase LrgA
EAE30_RS12550	COG1346	cytolysis
EAE30_RS12555	COG0295	cytidine deaminase activity
EAE30_RS12575	COG0500	methyltransferase
EAE30_RS12585	COG0776	regulation of translation
EAE30_RS12590	COG0072	phenylalanine-tRNA ligase activity
EAE30_RS12590	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EAE30_RS12630	COG0322	excinuclease ABC activity
EAE30_RS12635	COG2197	response regulator
EAE30_RS12640	COG0417	DNA replication proofreading
EAE30_RS12650	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EAE30_RS12660	COG3097	Belongs to the UPF0267 family
EAE30_RS12670	COG0277	FAD linked oxidase domain protein
EAE30_RS12670	COG0247	lactate metabolic process
EAE30_RS12695	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EAE30_RS12700	COG1609	Transcriptional regulator
EAE30_RS12710	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EAE30_RS12720	COG0281	malic enzyme
EAE30_RS12730	COG2949	membrane
EAE30_RS12740	COG0492	ferredoxin-NADP+ reductase activity
EAE30_RS12745	COG4988	ABC transporter
EAE30_RS12750	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EAE30_RS12755	COG1187	pseudouridine synthase activity
EAE30_RS12760	COG0009	L-threonylcarbamoyladenylate synthase
EAE30_RS12765	COG0613	PHP domain protein
EAE30_RS12775	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EAE30_RS12780	COG0512	Glutamine amidotransferase of anthranilate synthase
EAE30_RS12785	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EAE30_RS12790	COG0135	phosphoribosylanthranilate isomerase activity
EAE30_RS12790	COG0134	indole-3-glycerol-phosphate synthase activity
EAE30_RS12795	COG0133	tryptophan synthase activity
EAE30_RS12800	COG0159	tryptophan synthase activity
EAE30_RS12815	COG2350	Protein conserved in bacteria
EAE30_RS12825	COG0583	DNA-binding transcription factor activity
EAE30_RS12835	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EAE30_RS12855	COG3070	regulator of competence-specific genes
EAE30_RS12865	COG2431	L-lysine efflux transmembrane transporter activity
EAE30_RS12870	COG0076	glutamate decarboxylase activity
EAE30_RS12875	COG1737	Transcriptional regulator
EAE30_RS12880	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EAE30_RS12885	COG2985	domain, Protein
EAE30_RS12885	COG3273	potassium ion transport
EAE30_RS12890	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EAE30_RS12895	COG1960	acyl-CoA dehydrogenase activity
EAE30_RS12915	COG1063	alcohol dehydrogenase
EAE30_RS12935	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EAE30_RS12940	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
EAE30_RS12945	COG2885	chlorophyll binding
EAE30_RS12950	COG0823	Involved in the tonB-independent uptake of proteins
EAE30_RS12965	COG0811	peptide transport
EAE30_RS12970	COG0824	Thioesterase
EAE30_RS12980	COG4890	Cyd operon protein YbgT
EAE30_RS12985	COG1294	oxidase, subunit
EAE30_RS12990	COG1271	oxidase subunit
EAE30_RS12995	COG2255	four-way junction helicase activity
EAE30_RS13000	COG0632	four-way junction helicase activity
EAE30_RS13005	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
EAE30_RS13010	COG0215	cysteine-tRNA ligase activity
EAE30_RS13015	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EAE30_RS13020	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EAE30_RS13025	COG3012	SEC-C Motif Domain Protein
EAE30_RS13030	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
EAE30_RS13040	COG1199	ATP-dependent helicase activity
EAE30_RS13045	COG3923	Primosomal replication protein n
EAE30_RS13060	COG4160	amino acid transport
EAE30_RS13080	COG1882	Formate acetyltransferase
EAE30_RS13085	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EAE30_RS13090	COG3013	Belongs to the UPF0304 family
EAE30_RS13100	COG2766	serine protein kinase
EAE30_RS13105	COG2718	Belongs to the UPF0229 family
EAE30_RS13110	COG2719	SpoVR family
EAE30_RS13115	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
EAE30_RS13120	COG2835	tetraacyldisaccharide 4'-kinase activity
EAE30_RS13125	COG1663	tetraacyldisaccharide 4'-kinase activity
EAE30_RS13130	COG1132	(ABC) transporter
EAE30_RS13135	COG2333	competence protein COMEC
EAE30_RS13135	COG0658	competence protein
EAE30_RS13145	COG3385	transposase activity
EAE30_RS13150	COG4591	ABC-type transport system involved in lipoprotein release permease component
EAE30_RS13155	COG1136	(ABC) transporter
EAE30_RS13160	COG4591	ABC-type transport system involved in lipoprotein release permease component
EAE30_RS13170	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EAE30_RS13185	COG1252	NADH dehydrogenase
EAE30_RS13190	COG3150	esterase
EAE30_RS13215	COG0537	adenosine 5'-monophosphoramidase activity
EAE30_RS13225	COG2186	Transcriptional regulator
EAE30_RS13230	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EAE30_RS13235	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
EAE30_RS13240	COG1674	ftsk spoiiie
EAE30_RS13245	COG1522	sequence-specific DNA binding
EAE30_RS13250	COG0686	Belongs to the AlaDH PNT family
EAE30_RS13265	COG0284	orotidine-5'-phosphate decarboxylase activity
EAE30_RS13270	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
EAE30_RS13275	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
EAE30_RS13280	COG0776	regulation of translation
EAE30_RS13285	COG0539	negative regulation of cytoplasmic translation
EAE30_RS13290	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EAE30_RS13295	COG1555	photosystem II stabilization
EAE30_RS13300	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EAE30_RS13305	COG0776	regulation of translation
EAE30_RS13310	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EAE30_RS13315	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EAE30_RS13330	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EAE30_RS13335	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EAE30_RS13335	COG3153	acetyltransferase
EAE30_RS13340	COG2999	glutathione oxidoreductase activity
EAE30_RS13350	COG3940	Belongs to the glycosyl hydrolase 43 family
EAE30_RS13355	COG2211	Major facilitator Superfamily
EAE30_RS13385	COG0488	(ABC) transporter
EAE30_RS13405	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EAE30_RS13410	COG2951	lytic endotransglycosylase activity
EAE30_RS13415	COG3100	YcgL domain-containing protein
EAE30_RS13420	COG0850	regulation of cytokinetic process
EAE30_RS13425	COG2894	cell division
EAE30_RS13430	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
EAE30_RS13440	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
EAE30_RS13445	COG0318	PFAM AMP-dependent synthetase and ligase
EAE30_RS13450	COG2267	carboxylic ester hydrolase activity
EAE30_RS13465	COG1214	PFAM Peptidase M22, glycoprotease
EAE30_RS13470	COG1199	ATP-dependent helicase activity
EAE30_RS13480	COG0788	formyltetrahydrofolate deformylase activity
EAE30_RS13485	COG0616	signal peptide processing
EAE30_RS13490	COG0252	asparaginase activity
EAE30_RS13495	COG3139	Protein of unknown function (DUF1315)
EAE30_RS13505	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EAE30_RS13510	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EAE30_RS13520	COG2226	methyltransferase
EAE30_RS13535	COG3300	MHYT domain
EAE30_RS13535	COG5001	Diguanylate cyclase
EAE30_RS13590	COG4964	Belongs to the GSP D family
EAE30_RS13610	COG2983	Belongs to the UPF0260 family
EAE30_RS13620	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EAE30_RS13635	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EAE30_RS13640	COG0745	RESPONSE REGULATOR receiver
EAE30_RS13645	COG0583	DNA-binding transcription factor activity
EAE30_RS13650	COG0778	Nitroreductase
EAE30_RS13660	COG0183	Belongs to the thiolase family
EAE30_RS13665	COG2067	long-chain fatty acid transport protein
EAE30_RS13670	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EAE30_RS13675	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
EAE30_RS13685	COG0572	uridine kinase
EAE30_RS13690	COG0489	protein tyrosine kinase activity
EAE30_RS13695	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EAE30_RS13695	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EAE30_RS13720	COG0314	molybdopterin synthase activity
EAE30_RS13725	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EAE30_RS13730	COG0315	cyclic pyranopterin monophosphate synthase activity
EAE30_RS13735	COG0521	Mo-molybdopterin cofactor biosynthetic process
EAE30_RS13740	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EAE30_RS13745	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EAE30_RS13750	COG2198	Histidine kinase
EAE30_RS13755	COG2204	response regulator
EAE30_RS13760	COG0556	nucleotide-excision repair
EAE30_RS13770	COG0582	viral genome integration into host DNA
EAE30_RS13780	COG1518	maintenance of DNA repeat elements
EAE30_RS13825	COG2003	Belongs to the UPF0758 family
EAE30_RS13870	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EAE30_RS13870	COG1017	nitric oxide dioxygenase activity
EAE30_RS13875	COG3604	Transcriptional regulator
EAE30_RS13915	COG2433	Pfam Transposase IS66
EAE30_RS13945	COG0328	RNA-DNA hybrid ribonuclease activity
EAE30_RS13995	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EAE30_RS14000	COG0673	inositol 2-dehydrogenase activity
EAE30_RS14015	COG0431	NADPH-dependent FMN reductase
EAE30_RS14015	COG3976	FMN-binding domain protein
EAE30_RS14015	COG1053	succinate dehydrogenase
EAE30_RS14020	COG0604	alcohol dehydrogenase
EAE30_RS14035	COG3527	Alpha-acetolactate decarboxylase
EAE30_RS14045	COG4657	Part of a membrane complex involved in electron transport
EAE30_RS14050	COG2878	Part of a membrane complex involved in electron transport
EAE30_RS14055	COG4656	Part of a membrane complex involved in electron transport
EAE30_RS14060	COG4658	electron transport chain
EAE30_RS14065	COG4659	FMN binding
EAE30_RS14070	COG4660	Part of a membrane complex involved in electron transport
EAE30_RS14075	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EAE30_RS14080	COG0346	lactoylglutathione lyase activity
EAE30_RS14090	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EAE30_RS14095	COG2056	Na+-H+ antiporter family
EAE30_RS14100	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EAE30_RS14105	COG1286	toxin biosynthetic process
EAE30_RS14110	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
EAE30_RS14115	COG0285	dihydrofolate synthase activity
EAE30_RS14120	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EAE30_RS14125	COG0101	tRNA pseudouridine synthase activity
EAE30_RS14140	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EAE30_RS14140	COG1263	PTS System
EAE30_RS14145	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EAE30_RS14150	COG1846	Transcriptional regulator
EAE30_RS14150	COG1940	carbohydrate kinase activity
EAE30_RS14155	COG4651	solute:proton antiporter activity
EAE30_RS14155	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EAE30_RS14160	COG0367	asparagine synthase
EAE30_RS14175	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EAE30_RS14180	COG0563	adenylate kinase activity
EAE30_RS14185	COG0326	Molecular chaperone. Has ATPase activity
EAE30_RS14190	COG3710	Transcriptional regulator
EAE30_RS14200	COG1090	epimerase
EAE30_RS14205	COG0300	oxidoreductase activity
EAE30_RS14210	COG3118	belongs to the thioredoxin family
EAE30_RS14215	COG0789	Transcriptional regulator
EAE30_RS14220	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EAE30_RS14225	COG3115	cell septum assembly
EAE30_RS14230	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
EAE30_RS14235	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EAE30_RS14240	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EAE30_RS14245	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EAE30_RS14250	COG2190	(PTS) system
EAE30_RS14255	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EAE30_RS14265	COG1702	phosphate starvation-inducible protein PhoH
EAE30_RS14270	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EAE30_RS14275	COG4535	Mg2 and Co2 transporter CorC
EAE30_RS14280	COG0815	Transfers the fatty acyl group on membrane lipoproteins
EAE30_RS14290	COG0495	leucyl-tRNA aminoacylation
EAE30_RS14295	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
EAE30_RS14300	COG1466	dna polymerase III delta subunit
EAE30_RS14305	COG0799	negative regulation of ribosome biogenesis
EAE30_RS14310	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EAE30_RS14315	COG0768	penicillin binding
EAE30_RS14320	COG0772	Belongs to the SEDS family
EAE30_RS14325	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EAE30_RS14330	COG1686	Belongs to the peptidase S11 family
EAE30_RS14335	COG2921	Belongs to the UPF0250 family
EAE30_RS14340	COG0321	lipoyl(octanoyl) transferase activity
EAE30_RS14345	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EAE30_RS14360	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EAE30_RS14385	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EAE30_RS14390	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EAE30_RS14395	COG2011	ABC-type metal ion transport system permease component
EAE30_RS14400	COG1464	Belongs to the NlpA lipoprotein family
EAE30_RS14405	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
EAE30_RS14430	COG1611	Belongs to the LOG family
EAE30_RS14435	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EAE30_RS14440	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
EAE30_RS14445	COG2363	Small membrane protein
EAE30_RS14455	COG0583	DNA-binding transcription factor activity
EAE30_RS14460	COG0301	tRNA thio-modification
EAE30_RS14460	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EAE30_RS14470	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EAE30_RS14475	COG1722	exodeoxyribonuclease VII activity
EAE30_RS14480	COG0142	geranyltranstransferase activity
EAE30_RS14485	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EAE30_RS14490	COG0564	pseudouridine synthase activity
EAE30_RS14495	COG3098	single-species biofilm formation
EAE30_RS14520	COG1671	Belongs to the UPF0178 family
EAE30_RS14525	COG1720	tRNA m6t6A37 methyltransferase activity
EAE30_RS14530	COG0442	prolyl-tRNA aminoacylation
EAE30_RS14550	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
EAE30_RS14560	COG0583	DNA-binding transcription factor activity
EAE30_RS14570	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
EAE30_RS14595	COG4969	Belongs to the N-Me-Phe pilin family
EAE30_RS14600	COG0484	heat shock protein binding
EAE30_RS14610	COG0443	Heat shock 70 kDa protein
EAE30_RS14615	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EAE30_RS14620	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EAE30_RS14625	COG0497	DNA recombination
EAE30_RS14630	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EAE30_RS14635	COG2914	Belongs to the UPF0125 (RnfH) family
EAE30_RS14640	COG2867	negative regulation of translational initiation
EAE30_RS14645	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EAE30_RS14655	COG0582	viral genome integration into host DNA
EAE30_RS14695	COG0732	type I restriction modification DNA specificity domain
EAE30_RS14745	COG3706	GGDEF domain
EAE30_RS14785	COG3385	transposase activity
EAE30_RS14810	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
EAE30_RS14835	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EAE30_RS14840	COG1151	hydroxylamine reductase activity
EAE30_RS14845	COG3604	Transcriptional regulator
EAE30_RS14855	COG0737	Belongs to the 5'-nucleotidase family
EAE30_RS14860	COG3706	GGDEF domain
EAE30_RS14860	COG2203	Gaf domain
EAE30_RS14860	COG4251	negative regulation of phosphorylation
EAE30_RS14860	COG5001	Diguanylate cyclase
EAE30_RS14865	COG0840	transmembrane signaling receptor activity
EAE30_RS14890	COG1902	pentaerythritol trinitrate reductase activity
EAE30_RS14910	COG1122	ATPase activity
EAE30_RS14915	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EAE30_RS14920	COG1268	BioY protein
EAE30_RS14925	COG3850	Histidine kinase
EAE30_RS14930	COG2197	response regulator
EAE30_RS14935	COG2181	nitrate reductase activity
EAE30_RS14940	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
EAE30_RS14945	COG1140	nitrate reductase beta subunit
EAE30_RS14950	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EAE30_RS14955	COG2223	nitrite transmembrane transporter activity
EAE30_RS14960	COG0840	transmembrane signaling receptor activity
EAE30_RS14965	COG0840	transmembrane signaling receptor activity
EAE30_RS14975	COG3604	Transcriptional regulator
EAE30_RS14980	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EAE30_RS14980	COG1017	nitric oxide dioxygenase activity
EAE30_RS15005	COG4598	ABC transporter
EAE30_RS15010	COG4160	amino acid transport
EAE30_RS15025	COG2115	Belongs to the xylose isomerase family
EAE30_RS15030	COG0477	Major facilitator Superfamily
EAE30_RS15030	COG2814	Major facilitator Superfamily
EAE30_RS15035	COG1609	Transcriptional regulator
EAE30_RS15035	COG2207	Transcriptional regulator
EAE30_RS15040	COG1070	Carbohydrate kinase
EAE30_RS15045	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
EAE30_RS15050	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EAE30_RS15055	COG1984	allophanate hydrolase subunit 2
EAE30_RS15060	COG0402	S-adenosylhomocysteine deaminase activity
EAE30_RS15075	COG4565	transcriptional regulatory protein
EAE30_RS15080	COG0840	transmembrane signaling receptor activity
EAE30_RS15095	COG1584	GPR1 FUN34 yaaH family protein
EAE30_RS15100	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EAE30_RS15105	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EAE30_RS15110	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EAE30_RS15115	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EAE30_RS15120	COG1116	anion transmembrane transporter activity
EAE30_RS15125	COG0351	phosphomethylpyrimidine kinase
EAE30_RS15140	COG2194	sulfuric ester hydrolase activity
EAE30_RS15145	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EAE30_RS15180	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EAE30_RS15200	COG0667	Aldo Keto reductase
EAE30_RS15215	COG2010	Cytochrome c
EAE30_RS15215	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EAE30_RS15240	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EAE30_RS15265	COG2433	Pfam Transposase IS66
EAE30_RS15275	COG0519	Catalyzes the synthesis of GMP from XMP
EAE30_RS15275	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EAE30_RS15280	COG0517	IMP dehydrogenase activity
EAE30_RS15280	COG0516	GMP reductase activity
EAE30_RS15300	COG1160	GTP binding
EAE30_RS15305	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EAE30_RS15310	COG2976	Protein conserved in bacteria
EAE30_RS15315	COG0124	histidyl-tRNA synthetase
EAE30_RS15335	COG0105	UTP biosynthetic process
EAE30_RS15340	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EAE30_RS15345	COG2975	iron-sulfur cluster assembly
EAE30_RS15350	COG0633	Ferredoxin
EAE30_RS15355	COG0443	Heat shock 70 kDa protein
EAE30_RS15370	COG0822	iron-sulfur transferase activity
EAE30_RS15380	COG1959	2 iron, 2 sulfur cluster binding
EAE30_RS15385	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
EAE30_RS15390	COG0483	inositol monophosphate 1-phosphatase activity
EAE30_RS15395	COG1335	isochorismatase
EAE30_RS15400	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EAE30_RS15405	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EAE30_RS15410	COG1862	Preprotein translocase
EAE30_RS15415	COG0343	queuine tRNA-ribosyltransferase activity
EAE30_RS15420	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EAE30_RS15425	COG0517	IMP dehydrogenase activity
EAE30_RS15430	COG0583	DNA-binding transcription factor activity
EAE30_RS15435	COG0450	alkyl hydroperoxide reductase
EAE30_RS15440	COG0704	Plays a role in the regulation of phosphate uptake
EAE30_RS15445	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EAE30_RS15450	COG0581	inorganic phosphate transmembrane transporter activity
EAE30_RS15455	COG0573	inorganic phosphate transmembrane transporter activity
EAE30_RS15460	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EAE30_RS15465	COG0248	Ppx GppA phosphatase
EAE30_RS15475	COG5002	protein histidine kinase activity
EAE30_RS15480	COG0745	RESPONSE REGULATOR receiver
EAE30_RS15485	COG2974	May be involved in recombination
EAE30_RS15490	COG0826	peptidase U32
EAE30_RS15495	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EAE30_RS15535	COG0542	response to heat
EAE30_RS15540	COG1496	oxidoreductase activity
EAE30_RS15545	COG0564	pseudouridine synthase activity
EAE30_RS15550	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EAE30_RS15555	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EAE30_RS15560	COG0077	Prephenate dehydratase
EAE30_RS15560	COG1605	Chorismate mutase
EAE30_RS15565	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
EAE30_RS15570	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
EAE30_RS15580	COG0488	(ABC) transporter
EAE30_RS15590	COG0287	Prephenate dehydrogenase
EAE30_RS15590	COG1605	Chorismate mutase
EAE30_RS15595	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EAE30_RS15605	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
EAE30_RS15610	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EAE30_RS15625	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EAE30_RS15630	COG1047	Peptidyl-prolyl cis-trans
EAE30_RS15635	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EAE30_RS15640	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EAE30_RS15645	COG0196	riboflavin kinase activity
EAE30_RS15650	COG0728	peptidoglycan biosynthetic process
EAE30_RS15655	COG0268	Binds directly to 16S ribosomal RNA
EAE30_RS15660	COG0640	Transcriptional regulator
EAE30_RS15665	COG0583	DNA-binding transcription factor activity
EAE30_RS15670	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EAE30_RS15675	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EAE30_RS15680	COG0730	response to heat
EAE30_RS15690	COG0494	nUDIX hydrolase
EAE30_RS15700	COG0667	Aldo Keto reductase
EAE30_RS15710	COG2204	response regulator
EAE30_RS15715	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EAE30_RS15730	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EAE30_RS15735	COG0513	Belongs to the DEAD box helicase family
EAE30_RS15775	COG0835	chemotaxis
EAE30_RS15775	COG0784	Response regulator, receiver
EAE30_RS15780	COG5001	Diguanylate cyclase
EAE30_RS15780	COG4251	negative regulation of phosphorylation
EAE30_RS15780	COG3706	GGDEF domain
EAE30_RS15780	COG2203	Gaf domain
EAE30_RS15790	COG5001	Diguanylate cyclase
EAE30_RS15790	COG3300	MHYT domain
EAE30_RS15855	COG2176	DNA-directed DNA polymerase activity
EAE30_RS15860	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EAE30_RS15900	COG3550	peptidyl-serine autophosphorylation
EAE30_RS15905	COG3620	sequence-specific DNA binding
EAE30_RS15910	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EAE30_RS15930	COG3153	acetyltransferase
EAE30_RS15945	COG1185	polyribonucleotide nucleotidyltransferase activity
EAE30_RS15950	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EAE30_RS15955	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EAE30_RS15970	COG0195	Participates in both transcription termination and antitermination
EAE30_RS15975	COG0779	Required for maturation of 30S ribosomal subunits
EAE30_RS15990	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EAE30_RS15995	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EAE30_RS16000	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EAE30_RS16005	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EAE30_RS16010	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
EAE30_RS16015	COG1534	Rna-binding protein
EAE30_RS16020	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EAE30_RS16025	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
EAE30_RS16030	COG2027	D-alanyl-D-alanine carboxypeptidase
EAE30_RS16035	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EAE30_RS16040	COG0739	heme binding
EAE30_RS16045	COG0316	Belongs to the HesB IscA family
EAE30_RS16050	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EAE30_RS16055	COG0628	permease
EAE30_RS16060	COG2813	Specifically methylates the guanine in position
EAE30_RS16065	COG0004	ammonium transporteR
EAE30_RS16070	COG0347	Belongs to the P(II) protein family
EAE30_RS16075	COG3112	Uncharacterised protein family (UPF0231)
EAE30_RS16085	COG1752	Esterase of the alpha-beta hydrolase superfamily
EAE30_RS16090	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EAE30_RS16095	COG1643	Atp-dependent helicase
EAE30_RS16100	COG1489	DNA binding
EAE30_RS16105	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EAE30_RS16110	COG3385	transposase activity
EAE30_RS16115	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EAE30_RS16125	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EAE30_RS16135	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EAE30_RS16140	COG0842	Transport permease protein
EAE30_RS16145	COG1131	(ABC) transporter
EAE30_RS16150	COG0288	reversible hydration of carbon dioxide
EAE30_RS16165	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EAE30_RS16170	COG0508	dehydrogenase complex catalyzes the overall conversion of
EAE30_RS16175	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
EAE30_RS16180	COG2186	Transcriptional regulator
EAE30_RS16185	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EAE30_RS16190	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EAE30_RS16195	COG4974	Belongs to the 'phage' integrase family
EAE30_RS16200	COG0716	FMN binding
EAE30_RS16210	COG0157	Belongs to the NadC ModD family
EAE30_RS16220	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EAE30_RS16225	COG1459	type II secretion system
EAE30_RS16235	COG0237	dephospho-CoA kinase activity
EAE30_RS16240	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
EAE30_RS16260	COG3150	esterase
EAE30_RS16270	COG3151	Protein conserved in bacteria
EAE30_RS16275	COG0494	nUDIX hydrolase
EAE30_RS16280	COG1538	Outer membrane efflux protein
EAE30_RS16290	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
EAE30_RS16300	COG3025	triphosphatase activity
EAE30_RS16305	COG1392	Phosphate transport regulator
EAE30_RS16310	COG0306	phosphate transporter
EAE30_RS16315	COG4991	sh3 domain protein
EAE30_RS16325	COG3267	Type II secretory pathway component ExeA
EAE30_RS16325	COG3409	Peptidoglycan-binding domain 1 protein
EAE30_RS16330	COG0617	tRNA 3'-terminal CCA addition
EAE30_RS16335	COG0148	phosphopyruvate hydratase activity
EAE30_RS16340	COG0504	CTP synthase activity
EAE30_RS16345	COG3956	TIGRFAM MazG family protein
EAE30_RS16350	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EAE30_RS16355	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EAE30_RS16365	COG5520	Belongs to the glycosyl hydrolase 30 family
EAE30_RS16380	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
EAE30_RS16385	COG1381	Involved in DNA repair and RecF pathway recombination
EAE30_RS16390	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EAE30_RS16405	COG0481	GTPase activity
EAE30_RS16410	COG3086	response to oxidative stress
EAE30_RS16425	COG1595	DNA-templated transcription, initiation
EAE30_RS16430	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EAE30_RS16440	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
EAE30_RS16455	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EAE30_RS16460	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EAE30_RS16465	COG3079	Belongs to the UPF0149 family
EAE30_RS16470	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
EAE30_RS16480	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EAE30_RS16485	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EAE30_RS16490	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EAE30_RS16500	COG0028	Belongs to the TPP enzyme family
EAE30_RS16510	COG0583	DNA-binding transcription factor activity
EAE30_RS16525	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EAE30_RS16530	COG0473	3-isopropylmalate dehydrogenase activity
EAE30_RS16535	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EAE30_RS16540	COG0066	3-isopropylmalate dehydratase activity
EAE30_RS16590	COG0371	Dehydrogenase
EAE30_RS16595	COG0795	lipopolysaccharide-transporting ATPase activity
EAE30_RS16600	COG0795	lipopolysaccharide-transporting ATPase activity
EAE30_RS16615	COG0525	valine-tRNA ligase activity
EAE30_RS16635	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EAE30_RS16640	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EAE30_RS16645	COG0540	Belongs to the ATCase OTCase family
EAE30_RS16650	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
EAE30_RS16655	COG0251	oxidation-reduction process
EAE30_RS16670	COG5007	Belongs to the BolA IbaG family
EAE30_RS16675	COG3113	response to antibiotic
EAE30_RS16680	COG2854	intermembrane phospholipid transfer
EAE30_RS16685	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EAE30_RS16690	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EAE30_RS16695	COG1127	ABC transporter
EAE30_RS16705	COG0517	IMP dehydrogenase activity
EAE30_RS16705	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
EAE30_RS16710	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
EAE30_RS16720	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
EAE30_RS16725	COG1137	ATPase activity
EAE30_RS16735	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EAE30_RS16740	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EAE30_RS16745	COG1660	Displays ATPase and GTPase activities
EAE30_RS16750	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EAE30_RS16755	COG2239	Acts as a magnesium transporter
EAE30_RS16760	COG0312	modulator of DNA gyrase
EAE30_RS16765	COG3028	Belongs to the UPF0307 family
EAE30_RS16770	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
EAE30_RS16775	COG1178	ABC-type Fe3 transport system permease component
EAE30_RS16780	COG4143	(ABC) transporter
EAE30_RS16785	COG0163	prenyltransferase activity
EAE30_RS16790	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EAE30_RS16795	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
EAE30_RS16800	COG2105	PFAM AIG2 family protein
EAE30_RS16805	COG2911	Protein conserved in bacteria
EAE30_RS16810	COG0729	surface antigen
EAE30_RS16815	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EAE30_RS16835	COG0529	Catalyzes the synthesis of activated sulfate
EAE30_RS16840	COG2895	sulfate adenylyltransferase (ATP) activity
EAE30_RS16845	COG0175	sulfate reduction
EAE30_RS16850	COG1648	precorrin-2 dehydrogenase activity
EAE30_RS16850	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EAE30_RS16855	COG2153	protein acetylation
EAE30_RS16860	COG3061	Opacity-associated protein A
EAE30_RS16865	COG0545	Peptidyl-prolyl cis-trans isomerase
EAE30_RS16875	COG0203	ribosomal protein L17
EAE30_RS16880	COG0202	RNA polymerase activity
EAE30_RS16890	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EAE30_RS16895	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EAE30_RS16900	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EAE30_RS16905	COG0201	protein transport
EAE30_RS16910	COG0200	Binds to the 23S rRNA
EAE30_RS16915	COG1841	ribosomal large subunit assembly
EAE30_RS16930	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EAE30_RS16935	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EAE30_RS16940	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EAE30_RS16945	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EAE30_RS16955	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EAE30_RS16960	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EAE30_RS16965	COG0255	Belongs to the universal ribosomal protein uL29 family
EAE30_RS16970	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EAE30_RS16975	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EAE30_RS16980	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EAE30_RS16985	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EAE30_RS16995	COG0089	rRNA binding
EAE30_RS17000	COG0088	Forms part of the polypeptide exit tunnel
EAE30_RS17005	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EAE30_RS17015	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EAE30_RS17020	COG0557	exoribonuclease II activity
EAE30_RS17025	COG1132	(ABC) transporter
EAE30_RS17030	COG1132	(ABC) transporter
EAE30_RS17035	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
EAE30_RS17040	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EAE30_RS17045	COG1446	asparaginase
EAE30_RS17050	COG1047	Peptidyl-prolyl cis-trans
EAE30_RS17055	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
EAE30_RS17060	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EAE30_RS17060	COG0475	glutathione-regulated potassium exporter activity
EAE30_RS17065	COG2249	NAD(P)H dehydrogenase (quinone) activity
EAE30_RS17070	COG0488	(ABC) transporter
EAE30_RS17080	COG0429	hydrolase of the alpha beta-hydrolase fold
EAE30_RS17090	COG3954	Phosphoribulokinase
EAE30_RS17105	COG1012	belongs to the aldehyde dehydrogenase family
EAE30_RS17115	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EAE30_RS17140	COG0180	Tryptophanyl-tRNA synthetase
EAE30_RS17145	COG0546	phosphoglycolate phosphatase activity
EAE30_RS17150	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EAE30_RS17155	COG0338	D12 class N6 adenine-specific DNA methyltransferase
EAE30_RS17165	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EAE30_RS17170	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EAE30_RS17175	COG4796	Type ii and iii secretion system protein
EAE30_RS17200	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EAE30_RS17210	COG0678	peroxiredoxin activity
EAE30_RS17210	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EAE30_RS17230	COG0165	Argininosuccinate lyase
EAE30_RS17230	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
EAE30_RS17235	COG0137	argininosuccinate synthase activity
EAE30_RS17240	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EAE30_RS17245	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EAE30_RS17250	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EAE30_RS17255	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
EAE30_RS17260	COG1695	Transcriptional regulator
EAE30_RS17270	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EAE30_RS17275	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
EAE30_RS17280	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EAE30_RS17285	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
EAE30_RS17290	COG1053	succinate dehydrogenase
EAE30_RS17295	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EAE30_RS17305	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
EAE30_RS17310	COG0471	metal ion transport
EAE30_RS17315	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EAE30_RS17320	COG1509	lysine 2,3-aminomutase activity
EAE30_RS17325	COG1285	pathogenesis
EAE30_RS17330	COG1119	ATPase activity
EAE30_RS17360	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EAE30_RS17360	COG0574	Belongs to the PEP-utilizing enzyme family
EAE30_RS17365	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EAE30_RS17370	COG0459	protein refolding
EAE30_RS17395	COG0149	triose-phosphate isomerase activity
EAE30_RS17400	COG0534	Mate efflux family protein
EAE30_RS17405	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EAE30_RS17410	COG1575	Belongs to the MenA family. Type 1 subfamily
EAE30_RS17415	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EAE30_RS17420	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EAE30_RS17430	COG1609	Transcriptional regulator
EAE30_RS17435	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EAE30_RS17445	COG0281	malic enzyme
EAE30_RS17450	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
EAE30_RS17455	COG0626	cystathionine gamma-synthase activity
EAE30_RS17460	COG0527	aspartate kinase activity
EAE30_RS17460	COG0460	homoserine dehydrogenase
EAE30_RS17465	COG3074	FtsZ-dependent cytokinesis
EAE30_RS17470	COG1494	fructose-1,6-bisphosphatase
EAE30_RS17475	COG0205	6-phosphofructokinase activity
EAE30_RS17485	COG0745	RESPONSE REGULATOR receiver
EAE30_RS17490	COG2205	protein histidine kinase activity
EAE30_RS17500	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EAE30_RS17505	COG3030	protein affecting phage T7 exclusion by the F plasmid
EAE30_RS17520	COG1027	Aspartate ammonia-lyase
EAE30_RS17525	COG4232	protein-disulfide reductase activity
EAE30_RS17535	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EAE30_RS17540	COG0194	GDP metabolic process
EAE30_RS17545	COG1758	RNA polymerase activity
EAE30_RS17550	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EAE30_RS17555	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EAE30_RS17560	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EAE30_RS17570	COG2233	PERMEase
EAE30_RS17585	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EAE30_RS17605	COG0745	RESPONSE REGULATOR receiver
EAE30_RS17610	COG0642	Histidine kinase
EAE30_RS17615	COG2183	response to ionizing radiation
EAE30_RS17630	COG1040	competence protein
EAE30_RS17635	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EAE30_RS17635	COG0316	Belongs to the HesB IscA family
EAE30_RS17640	COG0494	nUDIX hydrolase
EAE30_RS17645	COG1218	3'(2'),5'-bisphosphate nucleotidase
EAE30_RS17655	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
EAE30_RS17660	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
EAE30_RS17665	COG3156	type II secretion system protein K
EAE30_RS17670	COG4795	General secretion pathway protein
EAE30_RS17675	COG2165	general secretion pathway protein
EAE30_RS17680	COG2165	general secretion pathway protein
EAE30_RS17685	COG2165	general secretion pathway protein
EAE30_RS17690	COG1459	type II secretion system
EAE30_RS17695	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EAE30_RS17705	COG3031	protein transport across the cell outer membrane
EAE30_RS17710	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EAE30_RS17720	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EAE30_RS17730	COG0456	acetyltransferase
EAE30_RS17735	COG1490	D-aminoacyl-tRNA deacylase activity
EAE30_RS17740	COG1295	ribonuclease BN
EAE30_RS17745	COG1217	gtp-binding protein TYPA
EAE30_RS17750	COG0174	glutamine synthetase
EAE30_RS17755	COG3852	Histidine kinase
EAE30_RS17760	COG2204	response regulator
EAE30_RS17765	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EAE30_RS17805	COG0724	RNA recognition motif
EAE30_RS17810	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EAE30_RS17815	COG4206	TonB-dependent receptor
EAE30_RS17825	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EAE30_RS17835	COG2423	ornithine cyclodeaminase activity
EAE30_RS17840	COG2207	Transcriptional regulator
EAE30_RS17845	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EAE30_RS17850	COG1484	DNA-dependent DNA replication
EAE30_RS17870	COG0270	DNA (cytosine-5-)-methyltransferase activity
EAE30_RS17895	COG2003	Belongs to the UPF0758 family
EAE30_RS17925	COG2433	Pfam Transposase IS66
EAE30_RS17995	COG0534	Mate efflux family protein
EAE30_RS18000	COG1472	Belongs to the glycosyl hydrolase 3 family
EAE30_RS18005	COG1472	Belongs to the glycosyl hydrolase 3 family
EAE30_RS18010	COG0395	ABC-type sugar transport system, permease component
EAE30_RS18015	COG1175	transmembrane transport
EAE30_RS18025	COG3842	ATPase activity
EAE30_RS18030	COG3842	ATPase activity
EAE30_RS18035	COG0454	-acetyltransferase
EAE30_RS18040	COG0583	DNA-binding transcription factor activity
EAE30_RS18055	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EAE30_RS18060	COG0534	Mate efflux family protein
EAE30_RS18070	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EAE30_RS18080	COG2937	Belongs to the GPAT DAPAT family
EAE30_RS18085	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EAE30_RS18110	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EAE30_RS18115	COG2177	Part of the ABC transporter FtsEX involved in
EAE30_RS18120	COG2884	Cell division ATP-binding protein ftsE
EAE30_RS18125	COG0552	protein localization to endoplasmic reticulum
EAE30_RS18130	COG0742	ribosomal rna small subunit methyltransferase
EAE30_RS18140	COG2095	MarC family integral membrane protein
EAE30_RS18165	COG0783	Belongs to the Dps family
EAE30_RS18170	COG2267	carboxylic ester hydrolase activity
EAE30_RS18175	COG0561	phosphatase activity
EAE30_RS18190	COG3148	PFAM DTW domain containing protein
EAE30_RS18195	COG1011	Hydrolase
EAE30_RS18210	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EAE30_RS18215	COG0019	diaminopimelate decarboxylase activity
EAE30_RS18225	COG1965	Belongs to the frataxin family
EAE30_RS18240	COG1587	Uroporphyrinogen-III synthase
EAE30_RS18245	COG2959	enzyme of heme biosynthesis
EAE30_RS18280	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EAE30_RS18280	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EAE30_RS18290	COG0084	hydrolase, TatD family'
EAE30_RS18295	COG0805	protein transport
EAE30_RS18300	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EAE30_RS18305	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EAE30_RS18320	COG2226	methyltransferase
EAE30_RS18325	COG1322	Protein conserved in bacteria
EAE30_RS18345	COG2160	L-arabinose isomerase activity
EAE30_RS18350	COG0235	Class ii aldolase
EAE30_RS18355	COG1069	ribulokinase activity
EAE30_RS18360	COG1879	ABC-type sugar transport system periplasmic component
EAE30_RS18365	COG1129	ABC transporter
EAE30_RS18370	COG1172	Belongs to the binding-protein-dependent transport system permease family
EAE30_RS18380	COG1879	ABC-type sugar transport system periplasmic component
EAE30_RS18385	COG1129	ABC transporter
EAE30_RS18390	COG1172	Belongs to the binding-protein-dependent transport system permease family
EAE30_RS18395	COG1172	Belongs to the binding-protein-dependent transport system permease family
EAE30_RS18405	COG3265	gluconokinase activity
EAE30_RS18410	COG2610	gluconate transmembrane transporter activity
EAE30_RS18415	COG1609	Transcriptional regulator
EAE30_RS18420	COG2081	HI0933 family
EAE30_RS18430	COG1528	Iron-storage protein
EAE30_RS18450	COG1522	sequence-specific DNA binding
EAE30_RS18465	COG0006	proline dipeptidase activity
EAE30_RS18465	COG0006	proline dipeptidase activity
EAE30_RS18470	COG1309	transcriptional regulator
EAE30_RS18475	COG1012	belongs to the aldehyde dehydrogenase family
EAE30_RS18490	COG4176	ABC-type proline glycine betaine transport system permease component
EAE30_RS18495	COG4175	Glycine betaine
EAE30_RS18500	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EAE30_RS18565	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EAE30_RS18570	COG1739	Uncharacterized protein family UPF0029
EAE30_RS18575	COG1250	3-hydroxyacyl-CoA dehydrogenase
EAE30_RS18575	COG1024	Enoyl-CoA hydratase
EAE30_RS18580	COG0183	Belongs to the thiolase family
EAE30_RS18590	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EAE30_RS18600	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EAE30_RS18605	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EAE30_RS18610	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EAE30_RS18615	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EAE30_RS18630	COG3312	ion transport
EAE30_RS18640	COG1475	DNA binding
EAE30_RS18645	COG1192	Involved in chromosome partitioning
EAE30_RS18650	COG0357	Ribosomal RNA small subunit methyltransferase G
EAE30_RS18655	COG0445	tRNA wobble uridine modification
EAE30_RS18660	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EAE30_RS18665	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EAE30_RS18685	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EAE30_RS18690	COG1126	abc transporter atp-binding protein