locus-tag	class	description
J4N38_RS00010	COG0592	DNA-directed DNA polymerase activity
J4N38_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
J4N38_RS00020	COG0187	DNA topoisomerase II activity
J4N38_RS00030	COG3977	Valine--pyruvate aminotransferase
J4N38_RS00040	COG0752	glycyl-tRNA synthetase alpha subunit
J4N38_RS00045	COG2119	membrane
J4N38_RS00055	COG0425	Belongs to the sulfur carrier protein TusA family
J4N38_RS00070	COG0604	alcohol dehydrogenase
J4N38_RS00080	COG0129	dihydroxy-acid dehydratase activity
J4N38_RS00085	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
J4N38_RS00090	COG3978	acetolactate synthase activity
J4N38_RS00135	COG0464	growth
J4N38_RS00140	COG1061	Type III restriction enzyme res subunit
J4N38_RS00205	COG0204	Acyl-transferase
J4N38_RS00210	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
J4N38_RS00215	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
J4N38_RS00225	COG3084	Protein conserved in bacteria
J4N38_RS00235	COG4326	sporulation control protein
J4N38_RS00240	COG1272	protein, Hemolysin III
J4N38_RS00250	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
J4N38_RS00255	COG0569	domain protein
J4N38_RS00260	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
J4N38_RS00260	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
J4N38_RS00275	COG0758	DNA mediated transformation
J4N38_RS00280	COG2922	Belongs to the Smg family
J4N38_RS00285	COG0551	DNA topoisomerase type I activity
J4N38_RS00290	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
J4N38_RS00295	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
J4N38_RS00305	COG0408	coproporphyrinogen oxidase activity
J4N38_RS00320	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
J4N38_RS00385	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
J4N38_RS00390	COG3300	MHYT domain
J4N38_RS00390	COG5001	Diguanylate cyclase
J4N38_RS00400	COG3852	Histidine kinase
J4N38_RS00405	COG0174	glutamine synthetase
J4N38_RS00410	COG1217	gtp-binding protein TYPA
J4N38_RS00425	COG1295	ribonuclease BN
J4N38_RS00430	COG1490	D-aminoacyl-tRNA deacylase activity
J4N38_RS00435	COG0456	acetyltransferase
J4N38_RS00445	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
J4N38_RS00450	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
J4N38_RS00455	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
J4N38_RS00460	COG3031	protein transport across the cell outer membrane
J4N38_RS00470	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
J4N38_RS00475	COG1459	type II secretion system
J4N38_RS00480	COG2165	general secretion pathway protein
J4N38_RS00485	COG2165	general secretion pathway protein
J4N38_RS00490	COG2165	general secretion pathway protein
J4N38_RS00495	COG4795	General secretion pathway protein
J4N38_RS00500	COG3156	type II secretion system protein K
J4N38_RS00505	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
J4N38_RS00510	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
J4N38_RS00530	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
J4N38_RS00540	COG2183	response to ionizing radiation
J4N38_RS00555	COG1040	competence protein
J4N38_RS00565	COG0494	nUDIX hydrolase
J4N38_RS00570	COG1218	3'(2'),5'-bisphosphate nucleotidase
J4N38_RS00575	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
J4N38_RS00580	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
J4N38_RS00585	COG1561	YicC-like family, N-terminal region
J4N38_RS00590	COG2252	PERMEase
J4N38_RS00595	COG0194	GDP metabolic process
J4N38_RS00600	COG1758	RNA polymerase activity
J4N38_RS00605	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
J4N38_RS00610	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J4N38_RS00615	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
J4N38_RS00620	COG1560	Kdo2-lipid A biosynthetic process
J4N38_RS00625	COG1560	Kdo2-lipid A biosynthetic process
J4N38_RS00630	COG1309	transcriptional regulator
J4N38_RS00640	COG2003	Belongs to the UPF0758 family
J4N38_RS00645	COG0227	Belongs to the bacterial ribosomal protein bL28 family
J4N38_RS00665	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
J4N38_RS00670	COG0859	PFAM glycosyl transferase family 9
J4N38_RS00675	COG0463	Glycosyl transferase, family 2
J4N38_RS00680	COG0859	PFAM glycosyl transferase family 9
J4N38_RS00685	COG3642	lipopolysaccharide core region biosynthetic process
J4N38_RS00735	COG1519	Transferase
J4N38_RS00750	COG0859	PFAM glycosyl transferase family 9
J4N38_RS00765	COG3307	-O-antigen
J4N38_RS00795	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
J4N38_RS00810	COG1132	(ABC) transporter
J4N38_RS00815	COG1086	Polysaccharide biosynthesis protein
J4N38_RS00820	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
J4N38_RS00825	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
J4N38_RS00830	COG2089	acid synthase
J4N38_RS00850	COG1083	cytidylyl-transferase
J4N38_RS00885	COG1215	transferase activity, transferring glycosyl groups
J4N38_RS00905	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
J4N38_RS00910	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J4N38_RS00915	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
J4N38_RS00915	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
J4N38_RS00920	COG0812	UDP-N-acetylmuramate dehydrogenase activity
J4N38_RS00960	COG1494	fructose-1,6-bisphosphatase
J4N38_RS00965	COG3074	FtsZ-dependent cytokinesis
J4N38_RS00970	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
J4N38_RS00975	COG0527	aspartate kinase activity
J4N38_RS00975	COG0460	homoserine dehydrogenase
J4N38_RS00980	COG0626	cystathionine gamma-synthase activity
J4N38_RS00985	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
J4N38_RS00990	COG0281	malic enzyme
J4N38_RS01000	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
J4N38_RS01005	COG1609	Transcriptional regulator
J4N38_RS01010	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
J4N38_RS01015	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
J4N38_RS01035	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
J4N38_RS01040	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
J4N38_RS01045	COG1053	succinate dehydrogenase
J4N38_RS01050	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
J4N38_RS01055	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J4N38_RS01090	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J4N38_RS01105	COG1045	serine acetyltransferase
J4N38_RS01110	COG1695	Transcriptional regulator
J4N38_RS01115	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
J4N38_RS01120	COG1573	uracil-dna glycosylase
J4N38_RS01125	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
J4N38_RS01135	COG1253	flavin adenine dinucleotide binding
J4N38_RS01150	COG0151	Belongs to the GarS family
J4N38_RS01155	COG0138	bifunctional purine biosynthesis protein purh
J4N38_RS01160	COG0789	Transcriptional regulator
J4N38_RS01165	COG2199	diguanylate cyclase activity
J4N38_RS01170	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
J4N38_RS01175	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
J4N38_RS01180	COG2264	protein methyltransferase activity
J4N38_RS01185	COG0439	Biotin carboxylase
J4N38_RS01190	COG0511	ligase activity, forming carbon-carbon bonds
J4N38_RS01195	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
J4N38_RS01200	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
J4N38_RS01215	COG2814	Major facilitator Superfamily
J4N38_RS01220	COG0784	Response regulator, receiver
J4N38_RS01220	COG2205	protein histidine kinase activity
J4N38_RS01225	COG1072	(Pantothenic acid kinase))
J4N38_RS01255	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
J4N38_RS01260	COG0250	Participates in transcription elongation, termination and antitermination
J4N38_RS01275	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
J4N38_RS01285	COG0085	RNA polymerase activity
J4N38_RS01290	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
J4N38_RS01295	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
J4N38_RS01300	COG1027	Aspartate ammonia-lyase
J4N38_RS01375	COG0512	Glutamine amidotransferase of anthranilate synthase
J4N38_RS01380	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
J4N38_RS01390	COG1012	belongs to the aldehyde dehydrogenase family
J4N38_RS01400	COG0688	phosphatidylethanolamine metabolic process
J4N38_RS01405	COG1162	GTPase activity
J4N38_RS01460	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
J4N38_RS01465	COG0802	atpase or kinase
J4N38_RS01470	COG0860	N-Acetylmuramoyl-L-alanine amidase
J4N38_RS01475	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
J4N38_RS01490	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
J4N38_RS01495	COG0330	HflC and HflK could
J4N38_RS01500	COG0330	HflC and HflK could
J4N38_RS01505	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
J4N38_RS01510	COG2900	Belongs to the SlyX family
J4N38_RS01520	COG0545	Peptidyl-prolyl cis-trans isomerase
J4N38_RS01525	COG2964	Protein conserved in bacteria
J4N38_RS01530	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
J4N38_RS01535	COG2923	Belongs to the DsrF TusC family
J4N38_RS01540	COG2168	tRNA wobble position uridine thiolation
J4N38_RS01550	COG0049	tRNA binding
J4N38_RS01555	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
J4N38_RS01560	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
J4N38_RS01565	COG2906	2 iron, 2 sulfur cluster binding
J4N38_RS01575	COG0360	Binds together with S18 to 16S ribosomal RNA
J4N38_RS01595	COG0305	Participates in initiation and elongation during chromosome replication
J4N38_RS01600	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
J4N38_RS01605	COG0432	Pfam Uncharacterised protein family UPF0047
J4N38_RS01630	COG1136	(ABC) transporter
J4N38_RS01645	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
J4N38_RS01655	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J4N38_RS01660	COG0729	surface antigen
J4N38_RS01665	COG2911	Protein conserved in bacteria
J4N38_RS01670	COG2105	PFAM AIG2 family protein
J4N38_RS01675	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
J4N38_RS01685	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
J4N38_RS01690	COG0163	prenyltransferase activity
J4N38_RS01695	COG4143	(ABC) transporter
J4N38_RS01700	COG1178	ABC-type Fe3 transport system permease component
J4N38_RS01705	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
J4N38_RS01715	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
J4N38_RS01730	COG0629	single-stranded DNA binding
J4N38_RS01735	COG2200	EAL domain
J4N38_RS01735	COG2199	diguanylate cyclase activity
J4N38_RS01760	COG3409	Peptidoglycan-binding domain 1 protein
J4N38_RS01760	COG3267	Type II secretory pathway component ExeA
J4N38_RS01770	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
J4N38_RS01775	COG1459	type II secretion system
J4N38_RS01785	COG2165	general secretion pathway protein
J4N38_RS01790	COG2165	general secretion pathway protein
J4N38_RS01820	COG1077	Cell shape determining protein MreB Mrl
J4N38_RS01825	COG1792	Involved in formation and maintenance of cell shape
J4N38_RS01830	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
J4N38_RS01835	COG0424	maF-like protein
J4N38_RS01845	COG3164	Protein of unknown function
J4N38_RS01850	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
J4N38_RS01855	COG0312	modulator of DNA gyrase
J4N38_RS01910	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
J4N38_RS01920	COG0220	tRNA (guanine-N7-)-methyltransferase activity
J4N38_RS01925	COG2066	Belongs to the glutaminase family
J4N38_RS01930	COG0635	Involved in the biosynthesis of porphyrin-containing compound
J4N38_RS01935	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
J4N38_RS01975	COG0762	integral membrane protein
J4N38_RS01980	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
J4N38_RS01985	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
J4N38_RS02000	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
J4N38_RS02005	COG1678	Uncharacterized ACR, COG1678
J4N38_RS02010	COG0189	ligase activity
J4N38_RS02015	COG1385	rRNA (uridine-N3-)-methyltransferase activity
J4N38_RS02020	COG2356	endonuclease I
J4N38_RS02025	COG3091	SprT-like family
J4N38_RS02035	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
J4N38_RS02045	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
J4N38_RS02055	COG0191	fructose-bisphosphate aldolase activity
J4N38_RS02060	COG0668	transmembrane transport
J4N38_RS02075	COG0583	DNA-binding transcription factor activity
J4N38_RS02085	COG3706	GGDEF domain
J4N38_RS02095	COG0469	pyruvate kinase activity
J4N38_RS02100	COG1349	DNA-binding transcription factor activity
J4N38_RS02105	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
J4N38_RS02130	COG0028	Belongs to the TPP enzyme family
J4N38_RS02135	COG1022	Amp-dependent synthetase and ligase
J4N38_RS02140	COG0583	DNA-binding transcription factor activity
J4N38_RS02155	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
J4N38_RS02160	COG0473	3-isopropylmalate dehydrogenase activity
J4N38_RS02175	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
J4N38_RS02180	COG1349	DNA-binding transcription factor activity
J4N38_RS02185	COG0469	pyruvate kinase activity
J4N38_RS02195	COG3706	GGDEF domain
J4N38_RS02205	COG0583	DNA-binding transcription factor activity
J4N38_RS02230	COG0191	fructose-bisphosphate aldolase activity
J4N38_RS02235	COG0668	transmembrane transport
J4N38_RS02250	COG0583	DNA-binding transcription factor activity
J4N38_RS02260	COG3706	GGDEF domain
J4N38_RS02270	COG0469	pyruvate kinase activity
J4N38_RS02275	COG1349	DNA-binding transcription factor activity
J4N38_RS02280	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
J4N38_RS02300	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
J4N38_RS02315	COG0583	DNA-binding transcription factor activity
J4N38_RS02320	COG1022	Amp-dependent synthetase and ligase
J4N38_RS02325	COG0028	Belongs to the TPP enzyme family
J4N38_RS02330	COG0440	acetolactate synthase activity
J4N38_RS02335	COG0584	glycerophosphoryl diester phosphodiesterase
J4N38_RS02340	COG2271	Major facilitator Superfamily
J4N38_RS02345	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
J4N38_RS02355	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
J4N38_RS02370	COG3079	Belongs to the UPF0149 family
J4N38_RS02375	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J4N38_RS02380	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J4N38_RS02395	COG0354	folic acid binding
J4N38_RS02400	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
J4N38_RS02405	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
J4N38_RS02410	COG1595	DNA-templated transcription, initiation
J4N38_RS02420	COG3026	antisigma factor binding
J4N38_RS02425	COG3086	response to oxidative stress
J4N38_RS02430	COG0481	GTPase activity
J4N38_RS02440	COG0571	ribonuclease III activity
J4N38_RS02445	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
J4N38_RS02450	COG1381	Involved in DNA repair and RecF pathway recombination
J4N38_RS02455	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
J4N38_RS02460	COG0736	holo-[acyl-carrier-protein] synthase activity
J4N38_RS02465	COG4999	Histidine kinase
J4N38_RS02465	COG3850	Histidine kinase
J4N38_RS02465	COG3437	response regulator, receiver
J4N38_RS02465	COG2205	protein histidine kinase activity
J4N38_RS02470	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
J4N38_RS02475	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
J4N38_RS02480	COG3956	TIGRFAM MazG family protein
J4N38_RS02490	COG0148	phosphopyruvate hydratase activity
J4N38_RS02495	COG0617	tRNA 3'-terminal CCA addition
J4N38_RS02500	COG3267	Type II secretory pathway component ExeA
J4N38_RS02500	COG3409	Peptidoglycan-binding domain 1 protein
J4N38_RS02510	COG4991	sh3 domain protein
J4N38_RS02515	COG0306	phosphate transporter
J4N38_RS02520	COG1392	Phosphate transport regulator
J4N38_RS02525	COG3025	triphosphatase activity
J4N38_RS02530	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J4N38_RS02540	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
J4N38_RS02545	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
J4N38_RS02545	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
J4N38_RS02550	COG0745	RESPONSE REGULATOR receiver
J4N38_RS02560	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
J4N38_RS02575	COG0083	homoserine kinase activity
J4N38_RS02580	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
J4N38_RS02585	COG2860	membrane
J4N38_RS02600	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
J4N38_RS02605	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
J4N38_RS02625	COG0534	Mate efflux family protein
J4N38_RS02630	COG2204	response regulator
J4N38_RS02640	COG0667	Aldo Keto reductase
J4N38_RS02650	COG3066	DNA modification
J4N38_RS02655	COG0494	nUDIX hydrolase
J4N38_RS02665	COG0730	response to heat
J4N38_RS02670	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
J4N38_RS02675	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
J4N38_RS02680	COG1283	sodium-dependent phosphate transmembrane transporter activity
J4N38_RS02685	COG0583	DNA-binding transcription factor activity
J4N38_RS02690	COG0640	Transcriptional regulator
J4N38_RS02695	COG0268	Binds directly to 16S ribosomal RNA
J4N38_RS02700	COG0728	peptidoglycan biosynthetic process
J4N38_RS02705	COG0196	riboflavin kinase activity
J4N38_RS02720	COG1047	Peptidyl-prolyl cis-trans
J4N38_RS02725	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
J4N38_RS02730	COG1966	Carbon starvation protein
J4N38_RS02740	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
J4N38_RS02745	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
J4N38_RS02760	COG1737	Transcriptional regulator
J4N38_RS02770	COG3279	Response regulator of the LytR AlgR family
J4N38_RS02775	COG3275	phosphorelay sensor kinase activity
J4N38_RS02780	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
J4N38_RS02785	COG0287	Prephenate dehydrogenase
J4N38_RS02785	COG1605	Chorismate mutase
J4N38_RS02790	COG0739	heme binding
J4N38_RS02800	COG0488	(ABC) transporter
J4N38_RS02805	COG0741	lytic transglycosylase activity
J4N38_RS02810	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
J4N38_RS02815	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
J4N38_RS02820	COG5001	Diguanylate cyclase
J4N38_RS02825	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
J4N38_RS02830	COG1605	Chorismate mutase
J4N38_RS02830	COG0077	Prephenate dehydratase
J4N38_RS02835	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
J4N38_RS02840	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
J4N38_RS02845	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J4N38_RS02850	COG0564	pseudouridine synthase activity
J4N38_RS02855	COG1496	oxidoreductase activity
J4N38_RS02860	COG0542	response to heat
J4N38_RS02905	COG0483	inositol monophosphate 1-phosphatase activity
J4N38_RS02910	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
J4N38_RS02920	COG1104	cysteine desulfurase activity
J4N38_RS02925	COG0822	iron-sulfur transferase activity
J4N38_RS02940	COG0443	Heat shock 70 kDa protein
J4N38_RS02945	COG0633	Ferredoxin
J4N38_RS02950	COG2975	iron-sulfur cluster assembly
J4N38_RS02965	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
J4N38_RS02970	COG0583	DNA-binding transcription factor activity
J4N38_RS02980	COG0583	DNA-binding transcription factor activity
J4N38_RS02985	COG1022	Amp-dependent synthetase and ligase
J4N38_RS02990	COG2169	Transcriptional regulator
J4N38_RS03020	COG4964	Belongs to the GSP D family
J4N38_RS03070	COG2059	Chromate
J4N38_RS03075	COG0583	DNA-binding transcription factor activity
J4N38_RS03085	COG2169	Transcriptional regulator
J4N38_RS03090	COG1486	melibiose metabolic process
J4N38_RS03095	COG2211	Major facilitator Superfamily
J4N38_RS03110	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
J4N38_RS03115	COG1085	galactose-1-phosphate uridylyltransferase
J4N38_RS03125	COG2017	converts alpha-aldose to the beta-anomer
J4N38_RS03130	COG1609	Transcriptional regulator
J4N38_RS03140	COG2211	Major facilitator Superfamily
J4N38_RS03165	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4N38_RS03165	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4N38_RS03165	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4N38_RS03175	COG2171	N-acyltransferase activity
J4N38_RS03180	COG0450	alkyl hydroperoxide reductase
J4N38_RS03185	COG0583	DNA-binding transcription factor activity
J4N38_RS03190	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
J4N38_RS03215	COG0517	IMP dehydrogenase activity
J4N38_RS03220	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
J4N38_RS03230	COG1862	Preprotein translocase
J4N38_RS03235	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J4N38_RS03240	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J4N38_RS03260	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
J4N38_RS03265	COG0826	peptidase U32
J4N38_RS03275	COG0745	RESPONSE REGULATOR receiver
J4N38_RS03280	COG5002	protein histidine kinase activity
J4N38_RS03290	COG0248	Ppx GppA phosphatase
J4N38_RS03295	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
J4N38_RS03305	COG0581	inorganic phosphate transmembrane transporter activity
J4N38_RS03310	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
J4N38_RS03315	COG0704	Plays a role in the regulation of phosphate uptake
J4N38_RS03335	COG3141	response to X-ray
J4N38_RS03350	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
J4N38_RS03355	COG1074	ATP-dependent DNA helicase activity
J4N38_RS03360	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
J4N38_RS03380	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
J4N38_RS03385	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
J4N38_RS03390	COG2166	iron-sulfur cluster assembly
J4N38_RS03405	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
J4N38_RS03410	COG0124	histidyl-tRNA synthetase
J4N38_RS03415	COG2976	Protein conserved in bacteria
J4N38_RS03420	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J4N38_RS03425	COG1160	GTP binding
J4N38_RS03430	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
J4N38_RS03450	COG0517	IMP dehydrogenase activity
J4N38_RS03450	COG0516	GMP reductase activity
J4N38_RS03465	COG1584	GPR1 FUN34 yaaH family protein
J4N38_RS03470	COG1115	amino acid carrier protein
J4N38_RS03480	COG0583	DNA-binding transcription factor activity
J4N38_RS03495	COG0784	Response regulator, receiver
J4N38_RS03495	COG0835	chemotaxis
J4N38_RS03500	COG0204	Acyl-transferase
J4N38_RS03515	COG0527	aspartate kinase activity
J4N38_RS03520	COG4251	negative regulation of phosphorylation
J4N38_RS03520	COG5001	Diguanylate cyclase
J4N38_RS03520	COG3706	GGDEF domain
J4N38_RS03520	COG2203	Gaf domain
J4N38_RS03525	COG3706	GGDEF domain
J4N38_RS03535	COG2239	Acts as a magnesium transporter
J4N38_RS03540	COG0189	ligase activity
J4N38_RS03540	COG4067	protein conserved in archaea
J4N38_RS03545	COG0189	ligase activity
J4N38_RS03565	COG2867	negative regulation of translational initiation
J4N38_RS03570	COG2914	Belongs to the UPF0125 (RnfH) family
J4N38_RS03575	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J4N38_RS03580	COG0497	DNA recombination
J4N38_RS03585	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
J4N38_RS03590	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
J4N38_RS03600	COG0443	Heat shock 70 kDa protein
J4N38_RS03635	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
J4N38_RS03645	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
J4N38_RS03650	COG0047	phosphoribosylformylglycinamidine synthase activity
J4N38_RS03650	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
J4N38_RS03675	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
J4N38_RS03680	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
J4N38_RS03685	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
J4N38_RS03690	COG1187	pseudouridine synthase activity
J4N38_RS03695	COG2840	Smr protein MutS2
J4N38_RS03720	COG3104	oligopeptide transport
J4N38_RS03725	COG0367	asparagine synthase
J4N38_RS03730	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
J4N38_RS03730	COG4651	solute:proton antiporter activity
J4N38_RS03735	COG1940	carbohydrate kinase activity
J4N38_RS03735	COG1846	Transcriptional regulator
J4N38_RS03740	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
J4N38_RS03745	COG2190	(PTS) system
J4N38_RS03745	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J4N38_RS03745	COG1263	PTS System
J4N38_RS03780	COG0330	HflC and HflK could
J4N38_RS03785	COG3118	belongs to the thioredoxin family
J4N38_RS03790	COG0300	oxidoreductase activity
J4N38_RS03795	COG1090	epimerase
J4N38_RS03820	COG0622	Phosphoesterase
J4N38_RS03840	COG3710	Transcriptional regulator
J4N38_RS03845	COG0326	Molecular chaperone. Has ATPase activity
J4N38_RS03855	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
J4N38_RS03865	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J4N38_RS03870	COG1611	Belongs to the LOG family
J4N38_RS03885	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
J4N38_RS03885	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
J4N38_RS03895	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
J4N38_RS03910	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
J4N38_RS03915	COG1393	Belongs to the ArsC family
J4N38_RS03940	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
J4N38_RS03950	COG0437	4 iron, 4 sulfur cluster binding
J4N38_RS03955	COG3301	Polysulphide reductase, NrfD
J4N38_RS03960	COG1138	Cytochrome C-type biogenesis protein
J4N38_RS03965	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J4N38_RS03970	COG3088	subunit of a heme lyase
J4N38_RS03970	COG4235	cytochrome complex assembly
J4N38_RS03980	COG2837	iron assimilation
J4N38_RS03985	COG2027	D-alanyl-D-alanine carboxypeptidase
J4N38_RS03995	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
J4N38_RS04000	COG0739	heme binding
J4N38_RS04015	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
J4N38_RS04025	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
J4N38_RS04035	COG1516	flagellar protein fliS
J4N38_RS04055	COG1677	Flagellar hook-basal body complex protein FliE
J4N38_RS04065	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
J4N38_RS04115	COG1987	bacterial-type flagellum assembly
J4N38_RS04120	COG1684	flagellar biosynthetic protein fliR
J4N38_RS04135	COG2890	protein-(glutamine-N5) methyltransferase activity
J4N38_RS04140	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
J4N38_RS04150	COG2860	membrane
J4N38_RS04155	COG3101	peptidyl-lysine hydroxylation
J4N38_RS04180	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
J4N38_RS04185	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
J4N38_RS04190	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
J4N38_RS04200	COG0101	tRNA pseudouridine synthase activity
J4N38_RS04205	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
J4N38_RS04210	COG0285	dihydrofolate synthase activity
J4N38_RS04215	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
J4N38_RS04220	COG1286	toxin biosynthetic process
J4N38_RS04225	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
J4N38_RS04230	COG1108	ABC-type Mn2 Zn2 transport systems permease components
J4N38_RS04235	COG1121	(ABC) transporter
J4N38_RS04240	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
J4N38_RS04245	COG4977	sequence-specific DNA binding
J4N38_RS04250	COG1918	ferrous iron import across plasma membrane
J4N38_RS04255	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
J4N38_RS04275	COG3102	Protein conserved in bacteria
J4N38_RS04280	COG1025	Belongs to the peptidase M16 family
J4N38_RS04285	COG2062	phosphohistidine phosphatase, SixA
J4N38_RS04315	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
J4N38_RS04320	COG2198	Histidine kinase
J4N38_RS04320	COG0784	Response regulator, receiver
J4N38_RS04320	COG0643	Histidine kinase
J4N38_RS04325	COG2201	protein-glutamate methylesterase activity
J4N38_RS04330	COG1192	Involved in chromosome partitioning
J4N38_RS04340	COG0835	chemotaxis
J4N38_RS04350	COG4133	protoheme IX ABC transporter activity
J4N38_RS04355	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
J4N38_RS04360	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
J4N38_RS04365	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
J4N38_RS04375	COG1138	Cytochrome C-type biogenesis protein
J4N38_RS04380	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J4N38_RS04395	COG2853	Lipoprotein
J4N38_RS04400	COG2067	long-chain fatty acid transport protein
J4N38_RS04405	COG2067	long-chain fatty acid transport protein
J4N38_RS04420	COG0183	Belongs to the thiolase family
J4N38_RS04430	COG0778	Nitroreductase
J4N38_RS04435	COG0583	DNA-binding transcription factor activity
J4N38_RS04440	COG0745	RESPONSE REGULATOR receiver
J4N38_RS04445	COG2832	Protein of unknown function (DUF454)
J4N38_RS04450	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
J4N38_RS04465	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
J4N38_RS04470	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
J4N38_RS04495	COG1653	transport
J4N38_RS04500	COG1175	transmembrane transport
J4N38_RS04510	COG3842	ATPase activity
J4N38_RS04515	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
J4N38_RS04520	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
J4N38_RS04525	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
J4N38_RS04535	COG2204	response regulator
J4N38_RS04555	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
J4N38_RS04560	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
J4N38_RS04565	COG0776	regulation of translation
J4N38_RS04570	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J4N38_RS04575	COG1555	photosystem II stabilization
J4N38_RS04580	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
J4N38_RS04585	COG0539	negative regulation of cytoplasmic translation
J4N38_RS04595	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
J4N38_RS04600	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
J4N38_RS04605	COG0284	orotidine-5'-phosphate decarboxylase activity
J4N38_RS04635	COG4120	Belongs to the binding-protein-dependent transport system permease family
J4N38_RS04645	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
J4N38_RS04660	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
J4N38_RS04665	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
J4N38_RS04670	COG0252	asparaginase activity
J4N38_RS04675	COG0616	signal peptide processing
J4N38_RS04680	COG0446	pyridine nucleotide-disulphide oxidoreductase
J4N38_RS04680	COG1902	pentaerythritol trinitrate reductase activity
J4N38_RS04685	COG0788	formyltetrahydrofolate deformylase activity
J4N38_RS04695	COG1199	ATP-dependent helicase activity
J4N38_RS04700	COG1214	PFAM Peptidase M22, glycoprotease
J4N38_RS04715	COG0596	Alpha beta hydrolase
J4N38_RS04720	COG0318	PFAM AMP-dependent synthetase and ligase
J4N38_RS04725	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
J4N38_RS04730	COG0659	secondary active sulfate transmembrane transporter activity
J4N38_RS04735	COG1530	ribonuclease E activity
J4N38_RS04740	COG0564	pseudouridine synthase activity
J4N38_RS04750	COG1399	metal-binding, possibly nucleic acid-binding protein
J4N38_RS04755	COG0333	Belongs to the bacterial ribosomal protein bL32 family
J4N38_RS04765	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
J4N38_RS04790	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
J4N38_RS04795	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
J4N38_RS04800	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
J4N38_RS04805	COG0470	DNA polymerase III
J4N38_RS04810	COG0084	hydrolase, TatD family'
J4N38_RS04815	COG1263	PTS System
J4N38_RS04815	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J4N38_RS04830	COG0733	neurotransmitter:sodium symporter activity
J4N38_RS04845	COG4667	esterase of the alpha-beta hydrolase superfamily
J4N38_RS04850	COG0702	epimerase
J4N38_RS04870	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
J4N38_RS04875	COG0840	transmembrane signaling receptor activity
J4N38_RS04880	COG0632	four-way junction helicase activity
J4N38_RS04885	COG2255	four-way junction helicase activity
J4N38_RS04890	COG1271	oxidase subunit
J4N38_RS04895	COG1294	oxidase, subunit
J4N38_RS04900	COG4890	Cyd operon protein YbgT
J4N38_RS04910	COG0824	Thioesterase
J4N38_RS04915	COG0811	peptide transport
J4N38_RS04930	COG0823	Involved in the tonB-independent uptake of proteins
J4N38_RS04935	COG2885	chlorophyll binding
J4N38_RS04940	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
J4N38_RS04945	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
J4N38_RS04960	COG0784	Response regulator, receiver
J4N38_RS04960	COG2205	protein histidine kinase activity
J4N38_RS04975	COG1401	restriction endodeoxyribonuclease activity
J4N38_RS04995	COG1902	pentaerythritol trinitrate reductase activity
J4N38_RS05000	COG1881	PFAM PEBP family protein
J4N38_RS05015	COG1940	carbohydrate kinase activity
J4N38_RS05035	COG1960	acyl-CoA dehydrogenase activity
J4N38_RS05040	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
J4N38_RS05050	COG0708	Exodeoxyribonuclease III
J4N38_RS05055	COG0840	transmembrane signaling receptor activity
J4N38_RS05060	COG2850	peptidyl-arginine hydroxylation
J4N38_RS05075	COG0730	response to heat
J4N38_RS05080	COG1199	ATP-dependent helicase activity
J4N38_RS05095	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
J4N38_RS05105	COG0156	8-amino-7-oxononanoate synthase activity
J4N38_RS05110	COG1073	alpha beta
J4N38_RS05110	COG2226	methyltransferase
J4N38_RS05115	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
J4N38_RS05125	COG0501	Belongs to the peptidase M48B family
J4N38_RS05135	COG1028	Short-chain dehydrogenase reductase Sdr
J4N38_RS05150	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
J4N38_RS05160	COG2268	Band 7 protein
J4N38_RS05170	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
J4N38_RS05180	COG0482	sulfurtransferase activity
J4N38_RS05190	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J4N38_RS05200	COG1757	Na H antiporter
J4N38_RS05210	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
J4N38_RS05220	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
J4N38_RS05220	COG0131	Imidazoleglycerol-phosphate dehydratase
J4N38_RS05225	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
J4N38_RS05230	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
J4N38_RS05240	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
J4N38_RS05240	COG0140	phosphoribosyl-ATP diphosphatase activity
J4N38_RS05245	COG2199	diguanylate cyclase activity
J4N38_RS05245	COG2200	EAL domain
J4N38_RS05245	COG2202	Pas domain
J4N38_RS05250	COG2205	protein histidine kinase activity
J4N38_RS05250	COG0784	Response regulator, receiver
J4N38_RS05270	COG1227	inorganic diphosphatase activity
J4N38_RS05280	COG4172	Belongs to the ABC transporter superfamily
J4N38_RS05290	COG4171	peptide transport system, permease
J4N38_RS05305	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
J4N38_RS05310	COG1842	Phage shock protein A
J4N38_RS05340	COG2818	Glycosylase
J4N38_RS05350	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
J4N38_RS05355	COG0626	cystathionine gamma-synthase activity
J4N38_RS05365	COG0733	neurotransmitter:sodium symporter activity
J4N38_RS05370	COG0564	pseudouridine synthase activity
J4N38_RS05375	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
J4N38_RS05385	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
J4N38_RS05390	COG4136	ATPase activity
J4N38_RS05395	COG4135	transport system, permease component
J4N38_RS05400	COG4134	Bacterial extracellular solute-binding protein
J4N38_RS05410	COG3313	Fe-S protein
J4N38_RS05425	COG2350	Protein conserved in bacteria
J4N38_RS05460	COG0776	regulation of translation
J4N38_RS05470	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
J4N38_RS05480	COG0417	DNA replication proofreading
J4N38_RS05495	COG2197	response regulator
J4N38_RS05500	COG0322	excinuclease ABC activity
J4N38_RS05530	COG1902	pentaerythritol trinitrate reductase activity
J4N38_RS05540	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
J4N38_RS05550	COG1032	radical SAM domain protein
J4N38_RS05575	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
J4N38_RS05585	COG1764	response to oxidative stress
J4N38_RS05590	COG1846	Transcriptional regulator
J4N38_RS05600	COG0583	DNA-binding transcription factor activity
J4N38_RS05625	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
J4N38_RS05675	COG0443	Heat shock 70 kDa protein
J4N38_RS05715	COG1643	Atp-dependent helicase
J4N38_RS05730	COG0159	tryptophan synthase activity
J4N38_RS05740	COG0134	indole-3-glycerol-phosphate synthase activity
J4N38_RS05740	COG0135	phosphoribosylanthranilate isomerase activity
J4N38_RS05745	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
J4N38_RS05750	COG0512	Glutamine amidotransferase of anthranilate synthase
J4N38_RS05755	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
J4N38_RS05765	COG0613	PHP domain protein
J4N38_RS05770	COG0009	L-threonylcarbamoyladenylate synthase
J4N38_RS05785	COG1187	pseudouridine synthase activity
J4N38_RS05790	COG0384	phenazine biosynthesis protein PhzF
J4N38_RS05795	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
J4N38_RS05800	COG4988	ABC transporter
J4N38_RS05805	COG0492	ferredoxin-NADP+ reductase activity
J4N38_RS05820	COG0612	Peptidase, M16
J4N38_RS05830	COG2949	membrane
J4N38_RS05840	COG0281	malic enzyme
J4N38_RS05845	COG1643	Atp-dependent helicase
J4N38_RS05860	COG1448	Aminotransferase
J4N38_RS05865	COG2770	Histidine kinase
J4N38_RS05865	COG3437	response regulator, receiver
J4N38_RS05875	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J4N38_RS05885	COG0017	Asparaginyl-tRNA synthetase
J4N38_RS05890	COG0840	transmembrane signaling receptor activity
J4N38_RS05895	COG0720	synthase
J4N38_RS05900	COG0814	amino acid
J4N38_RS05910	COG1760	l-serine dehydratase
J4N38_RS05915	COG0814	amino acid
J4N38_RS05920	COG0494	nUDIX hydrolase
J4N38_RS05935	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
J4N38_RS05950	COG3106	COG3106 Predicted ATPase
J4N38_RS05965	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J4N38_RS05995	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
J4N38_RS06020	COG2989	Protein conserved in bacteria
J4N38_RS06025	COG3108	Peptidase M15
J4N38_RS06030	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J4N38_RS06045	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
J4N38_RS06075	COG0783	Belongs to the Dps family
J4N38_RS06085	COG0531	amino acid
J4N38_RS06090	COG2962	Rard protein
J4N38_RS06115	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
J4N38_RS06125	COG1942	4-Oxalocrotonate Tautomerase
J4N38_RS06220	COG0346	lactoylglutathione lyase activity
J4N38_RS06395	COG0251	oxidation-reduction process
J4N38_RS06435	COG1028	Short-chain dehydrogenase reductase Sdr
J4N38_RS06505	COG4628	conserved protein (DUF2132)
J4N38_RS06730	COG3385	transposase activity
J4N38_RS06870	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
J4N38_RS06910	COG3755	Protein conserved in bacteria
J4N38_RS06940	COG0384	phenazine biosynthesis protein PhzF
J4N38_RS07055	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
J4N38_RS07130	COG0384	phenazine biosynthesis protein PhzF
J4N38_RS07190	COG3385	transposase activity
J4N38_RS07215	COG1280	lysine exporter protein (LysE YggA)
J4N38_RS07220	COG2161	toxin-antitoxin pair type II binding
J4N38_RS07225	COG4115	mRNA cleavage
J4N38_RS07240	COG0384	phenazine biosynthesis protein PhzF
J4N38_RS07325	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
J4N38_RS07335	COG0625	glutathione transferase activity
J4N38_RS07350	COG2885	chlorophyll binding
J4N38_RS07365	COG0247	lactate metabolic process
J4N38_RS07365	COG0277	FAD linked oxidase domain protein
J4N38_RS07380	COG2986	histidine ammonia-lyase
J4N38_RS07390	COG0010	Belongs to the arginase family
J4N38_RS07395	COG1228	amidohydrolase
J4N38_RS07400	COG2188	Transcriptional regulator
J4N38_RS07405	COG4326	sporulation control protein
J4N38_RS07425	COG0500	methyltransferase
J4N38_RS07430	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
J4N38_RS07440	COG0295	cytidine deaminase activity
J4N38_RS07445	COG1346	cytolysis
J4N38_RS07450	COG1380	Effector of murein hydrolase LrgA
J4N38_RS07455	COG2925	Exonuclease
J4N38_RS07460	COG1823	symporter activity
J4N38_RS07465	COG0702	epimerase
J4N38_RS07470	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
J4N38_RS07475	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
J4N38_RS07480	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
J4N38_RS07500	COG4139	cobalamin transport
J4N38_RS07505	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
J4N38_RS07530	COG0583	DNA-binding transcription factor activity
J4N38_RS07535	COG1119	ATPase activity
J4N38_RS07545	COG2205	protein histidine kinase activity
J4N38_RS07545	COG0784	Response regulator, receiver
J4N38_RS07555	COG1451	nucleotide metabolic process
J4N38_RS07575	COG0508	dehydrogenase complex catalyzes the overall conversion of
J4N38_RS07575	COG0596	Alpha beta hydrolase
J4N38_RS07580	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
J4N38_RS07595	COG2200	EAL domain
J4N38_RS07610	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J4N38_RS07635	COG0515	serine threonine protein kinase
J4N38_RS07750	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
J4N38_RS07755	COG0372	Belongs to the citrate synthase family
J4N38_RS07765	COG2828	Protein conserved in bacteria
J4N38_RS07785	COG0561	phosphatase activity
J4N38_RS07790	COG0602	queuosine metabolic process
J4N38_RS07825	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
J4N38_RS07830	COG0840	transmembrane signaling receptor activity
J4N38_RS07835	COG1254	Belongs to the acylphosphatase family
J4N38_RS07840	COG2920	part of a sulfur-relay system
J4N38_RS07845	COG0670	Belongs to the BI1 family
J4N38_RS07850	COG1126	abc transporter atp-binding protein
J4N38_RS07855	COG0765	amino acid transport
J4N38_RS07860	COG4597	amino acid ABC transporter
J4N38_RS07865	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J4N38_RS07870	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
J4N38_RS07870	COG1648	precorrin-2 dehydrogenase activity
J4N38_RS07880	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
J4N38_RS07885	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
J4N38_RS07905	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
J4N38_RS07905	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
J4N38_RS07910	COG3008	intermembrane lipid transfer
J4N38_RS07915	COG2995	paraquat-inducible protein a
J4N38_RS07920	COG1132	(ABC) transporter
J4N38_RS07925	COG1956	GAF domain-containing protein
J4N38_RS07930	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
J4N38_RS07945	COG0308	aminopeptidase N
J4N38_RS07960	COG0167	dihydroorotate dehydrogenase activity
J4N38_RS07970	COG0116	Belongs to the methyltransferase superfamily
J4N38_RS07970	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
J4N38_RS07980	COG0488	(ABC) transporter
J4N38_RS07995	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
J4N38_RS08000	COG1067	ATP-dependent peptidase activity
J4N38_RS08005	COG3120	sequence-specific DNA binding
J4N38_RS08050	COG0840	transmembrane signaling receptor activity
J4N38_RS08055	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
J4N38_RS08195	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J4N38_RS08210	COG3278	Belongs to the heme-copper respiratory oxidase family
J4N38_RS08225	COG2010	Cytochrome c
J4N38_RS08235	COG2217	Heavy metal translocating P-type atpase
J4N38_RS08250	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J4N38_RS08255	COG0589	response to stress
J4N38_RS08280	COG3842	ATPase activity
J4N38_RS08290	COG1177	transmembrane transport
J4N38_RS08295	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
J4N38_RS08305	COG2199	diguanylate cyclase activity
J4N38_RS08310	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
J4N38_RS08325	COG0583	DNA-binding transcription factor activity
J4N38_RS08340	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
J4N38_RS08375	COG0488	(ABC) transporter
J4N38_RS08385	COG1595	DNA-templated transcription, initiation
J4N38_RS08395	COG1910	domain protein
J4N38_RS08400	COG0746	molybdenum cofactor guanylyltransferase activity
J4N38_RS08405	COG1763	Mo-molybdopterin cofactor biosynthetic process
J4N38_RS08435	COG1940	carbohydrate kinase activity
J4N38_RS08440	COG3148	PFAM DTW domain containing protein
J4N38_RS08450	COG0840	transmembrane signaling receptor activity
J4N38_RS08450	COG3290	protein histidine kinase activity
J4N38_RS08455	COG0791	NLP P60 protein
J4N38_RS08465	COG3001	Fructosamine kinase
J4N38_RS08475	COG0307	riboflavin synthase, alpha
J4N38_RS08480	COG0534	Mate efflux family protein
J4N38_RS08525	COG2204	response regulator
J4N38_RS08535	COG0438	transferase activity, transferring glycosyl groups
J4N38_RS08570	COG0297	glycogen (starch) synthase activity
J4N38_RS08580	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
J4N38_RS08600	COG1196	nuclear chromosome segregation
J4N38_RS08615	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
J4N38_RS08660	COG3293	Transposase
J4N38_RS08690	COG4774	siderophore transport
J4N38_RS08710	COG4615	Cyclic peptide transporter
J4N38_RS08720	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
J4N38_RS08725	COG1120	ATPase activity
J4N38_RS08730	COG2977	Belongs to the P-Pant transferase superfamily
J4N38_RS08735	COG1929	Belongs to the glycerate kinase type-1 family
J4N38_RS08740	COG3835	regulator
J4N38_RS08745	COG0583	DNA-binding transcription factor activity
J4N38_RS08755	COG3385	transposase activity
J4N38_RS08760	COG3713	MltA-interacting MipA family protein
J4N38_RS08765	COG2205	protein histidine kinase activity
J4N38_RS08770	COG0745	RESPONSE REGULATOR receiver
J4N38_RS08790	COG2116	formate transmembrane transporter activity
J4N38_RS08800	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
J4N38_RS08805	COG2199	diguanylate cyclase activity
J4N38_RS08810	COG2195	Cleaves the N-terminal amino acid of tripeptides
J4N38_RS08835	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J4N38_RS08840	COG0454	-acetyltransferase
J4N38_RS08885	COG3122	Protein conserved in bacteria
J4N38_RS08905	COG4565	transcriptional regulatory protein
J4N38_RS08910	COG3290	protein histidine kinase activity
J4N38_RS08930	COG0848	biopolymer transport protein
J4N38_RS08935	COG0811	peptide transport
J4N38_RS08940	COG0811	peptide transport
J4N38_RS08975	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
J4N38_RS08980	COG1328	CTP reductase activity
J4N38_RS08985	COG0840	transmembrane signaling receptor activity
J4N38_RS08995	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
J4N38_RS09000	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
J4N38_RS09005	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
J4N38_RS09010	COG0633	Ferredoxin
J4N38_RS09035	COG0019	diaminopimelate decarboxylase activity
J4N38_RS09060	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
J4N38_RS09070	COG0577	efflux transmembrane transporter activity
J4N38_RS09075	COG1136	(ABC) transporter
J4N38_RS09080	COG0534	Mate efflux family protein
J4N38_RS09085	COG0702	epimerase
J4N38_RS09095	COG2814	Major facilitator Superfamily
J4N38_RS09105	COG1061	Type III restriction enzyme res subunit
J4N38_RS09145	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J4N38_RS09150	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J4N38_RS09165	COG0463	Glycosyl transferase, family 2
J4N38_RS09220	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
J4N38_RS09270	COG0242	peptide deformylase activity
J4N38_RS09275	COG0519	Catalyzes the synthesis of GMP from XMP
J4N38_RS09285	COG4580	involved in the transport of maltose and maltodextrins
J4N38_RS09290	COG3040	lipid binding
J4N38_RS09300	COG2824	Alkylphosphonate utilization operon protein PhnA
J4N38_RS09350	COG1115	amino acid carrier protein
J4N38_RS09355	COG1280	lysine exporter protein (LysE YggA)
J4N38_RS09360	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
J4N38_RS09365	COG0352	thiamine-phosphate diphosphorylase activity
J4N38_RS09380	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
J4N38_RS09390	COG1012	belongs to the aldehyde dehydrogenase family
J4N38_RS09400	COG0583	DNA-binding transcription factor activity
J4N38_RS09420	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
J4N38_RS09430	COG1609	Transcriptional regulator
J4N38_RS09435	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
J4N38_RS09445	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
J4N38_RS09445	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
J4N38_RS09460	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J4N38_RS09465	COG1609	Transcriptional regulator
J4N38_RS09480	COG1278	Cold shock
J4N38_RS09505	COG1538	Outer membrane efflux protein
J4N38_RS09510	COG1858	cytochrome C peroxidase
J4N38_RS09515	COG0784	Response regulator, receiver
J4N38_RS09515	COG2205	protein histidine kinase activity
J4N38_RS09535	COG0277	FAD linked oxidase domain protein
J4N38_RS09540	COG0583	DNA-binding transcription factor activity
J4N38_RS09560	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J4N38_RS09600	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J4N38_RS09600	COG0072	phenylalanine-tRNA ligase activity
J4N38_RS09630	COG2133	pyrroloquinoline quinone binding
J4N38_RS09640	COG4191	Histidine kinase
J4N38_RS09655	COG3070	regulator of competence-specific genes
J4N38_RS09665	COG2431	L-lysine efflux transmembrane transporter activity
J4N38_RS09675	COG0076	glutamate decarboxylase activity
J4N38_RS09680	COG1737	Transcriptional regulator
J4N38_RS09685	COG1454	alcohol dehydrogenase
J4N38_RS09685	COG1012	belongs to the aldehyde dehydrogenase family
J4N38_RS09690	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
J4N38_RS09725	COG1882	Formate acetyltransferase
J4N38_RS09740	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
J4N38_RS09750	COG3013	Belongs to the UPF0304 family
J4N38_RS09755	COG2766	serine protein kinase
J4N38_RS09760	COG2718	Belongs to the UPF0229 family
J4N38_RS09765	COG2719	SpoVR family
J4N38_RS09770	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
J4N38_RS09775	COG2835	tetraacyldisaccharide 4'-kinase activity
J4N38_RS09785	COG1132	(ABC) transporter
J4N38_RS09790	COG2333	competence protein COMEC
J4N38_RS09790	COG0658	competence protein
J4N38_RS09800	COG4591	ABC-type transport system involved in lipoprotein release permease component
J4N38_RS09805	COG1136	(ABC) transporter
J4N38_RS09810	COG4591	ABC-type transport system involved in lipoprotein release permease component
J4N38_RS09820	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
J4N38_RS09835	COG1252	NADH dehydrogenase
J4N38_RS09840	COG3150	esterase
J4N38_RS09865	COG0537	adenosine 5'-monophosphoramidase activity
J4N38_RS09880	COG2186	Transcriptional regulator
J4N38_RS09885	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
J4N38_RS09895	COG1674	ftsk spoiiie
J4N38_RS09905	COG0686	Belongs to the AlaDH PNT family
J4N38_RS09910	COG3092	negative regulation of chromosome organization
J4N38_RS09915	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
J4N38_RS09920	COG0280	phosphate acetyltransferase
J4N38_RS09920	COG0857	belongs to the CobB CobQ family
J4N38_RS09925	COG0435	Glutathione S-transferase
J4N38_RS09935	COG0444	Belongs to the ABC transporter superfamily
J4N38_RS09940	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J4N38_RS09945	COG0601	transmembrane transport
J4N38_RS09960	COG2067	long-chain fatty acid transport protein
J4N38_RS09970	COG0840	transmembrane signaling receptor activity
J4N38_RS09980	COG1404	Belongs to the peptidase S8 family
J4N38_RS09985	COG0840	transmembrane signaling receptor activity
J4N38_RS10010	COG1136	(ABC) transporter
J4N38_RS10010	COG0577	efflux transmembrane transporter activity
J4N38_RS10020	COG0577	efflux transmembrane transporter activity
J4N38_RS10030	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J4N38_RS10045	COG1770	oligopeptidase
J4N38_RS10135	COG3706	GGDEF domain
J4N38_RS10150	COG3126	Type III secretion system lipoprotein chaperone (YscW)
J4N38_RS10155	COG1946	Acyl-CoA thioesterase
J4N38_RS10160	COG1522	sequence-specific DNA binding
J4N38_RS10185	COG0477	Major facilitator Superfamily
J4N38_RS10190	COG2855	membrane
J4N38_RS10220	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
J4N38_RS10225	COG1169	isochorismate synthase
J4N38_RS10230	COG0436	Aminotransferase
J4N38_RS10235	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
J4N38_RS10240	COG0232	Belongs to the dGTPase family. Type 2 subfamily
J4N38_RS10245	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
J4N38_RS10260	COG0513	Belongs to the DEAD box helicase family
J4N38_RS10270	COG0616	signal peptide processing
J4N38_RS10275	COG1028	Short-chain dehydrogenase reductase Sdr
J4N38_RS10280	COG0469	pyruvate kinase activity
J4N38_RS10285	COG1940	carbohydrate kinase activity
J4N38_RS10290	COG0784	Response regulator, receiver
J4N38_RS10290	COG0835	chemotaxis
J4N38_RS10305	COG0243	molybdopterin cofactor binding
J4N38_RS10310	COG3005	denitrification pathway
J4N38_RS10315	COG4459	periplasmic nitrate reductase
J4N38_RS10320	COG0390	transport system, permease component
J4N38_RS10330	COG2116	formate transmembrane transporter activity
J4N38_RS10355	COG0542	response to heat
J4N38_RS10365	COG1278	Cold shock
J4N38_RS10375	COG1187	pseudouridine synthase activity
J4N38_RS10385	COG1801	Protein of unknown function DUF72
J4N38_RS10395	COG0500	methyltransferase
J4N38_RS10400	COG0189	ligase activity
J4N38_RS10400	COG4067	protein conserved in archaea
J4N38_RS10415	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
J4N38_RS10420	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
J4N38_RS10430	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
J4N38_RS10435	COG1434	Gram-negative-bacterium-type cell wall biogenesis
J4N38_RS10440	COG0745	RESPONSE REGULATOR receiver
J4N38_RS10455	COG3070	regulator of competence-specific genes
J4N38_RS10460	COG3385	transposase activity
J4N38_RS10480	COG0297	glycogen (starch) synthase activity
J4N38_RS10485	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
J4N38_RS10490	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
J4N38_RS10510	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
J4N38_RS10515	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
J4N38_RS10520	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
J4N38_RS10525	COG1435	thymidine kinase activity
J4N38_RS10530	COG0215	cysteine-tRNA ligase activity
J4N38_RS10535	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
J4N38_RS10540	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J4N38_RS10545	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
J4N38_RS10550	COG3012	SEC-C Motif Domain Protein
J4N38_RS10555	COG3139	Protein of unknown function (DUF1315)
J4N38_RS10565	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J4N38_RS10580	COG2226	methyltransferase
J4N38_RS10595	COG1785	Belongs to the alkaline phosphatase family
J4N38_RS10600	COG2771	luxR family
J4N38_RS10610	COG2814	Major facilitator Superfamily
J4N38_RS10615	COG1028	Short-chain dehydrogenase reductase Sdr
J4N38_RS10640	COG2951	lytic endotransglycosylase activity
J4N38_RS10645	COG3100	YcgL domain-containing protein
J4N38_RS10650	COG0850	regulation of cytokinetic process
J4N38_RS10655	COG2894	cell division
J4N38_RS10660	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
J4N38_RS10665	COG1454	alcohol dehydrogenase
J4N38_RS10665	COG1012	belongs to the aldehyde dehydrogenase family
J4N38_RS10670	COG2095	MarC family integral membrane protein
J4N38_RS10675	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J4N38_RS10680	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
J4N38_RS10685	COG1757	Na H antiporter
J4N38_RS10690	COG2188	Transcriptional regulator
J4N38_RS10695	COG1263	PTS System
J4N38_RS10695	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J4N38_RS10700	COG1621	beta-fructofuranosidase activity
J4N38_RS10710	COG3081	Nucleoid-associated protein
J4N38_RS10715	COG3082	Protein of unknown function (DUF1414)
J4N38_RS10720	COG3083	sulfuric ester hydrolase activity
J4N38_RS10745	COG0123	including yeast histone deacetylase and acetoin utilization protein
J4N38_RS10755	COG1881	PFAM PEBP family protein
J4N38_RS10765	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
J4N38_RS10770	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
J4N38_RS10790	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
J4N38_RS10795	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
J4N38_RS10835	COG0383	alpha-mannosidase activity
J4N38_RS10855	COG1940	carbohydrate kinase activity
J4N38_RS10860	COG2982	Protein involved in outer membrane biogenesis
J4N38_RS10865	COG0572	uridine kinase
J4N38_RS10870	COG0489	protein tyrosine kinase activity
J4N38_RS10875	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J4N38_RS10875	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J4N38_RS10905	COG0517	IMP dehydrogenase activity
J4N38_RS10905	COG0617	tRNA 3'-terminal CCA addition
J4N38_RS10905	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
J4N38_RS10915	COG3706	GGDEF domain
J4N38_RS10920	COG0314	molybdopterin synthase activity
J4N38_RS10925	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
J4N38_RS10930	COG0315	cyclic pyranopterin monophosphate synthase activity
J4N38_RS10935	COG0521	Mo-molybdopterin cofactor biosynthetic process
J4N38_RS10940	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
J4N38_RS10945	COG0391	Required for morphogenesis under gluconeogenic growth conditions
J4N38_RS10950	COG2198	Histidine kinase
J4N38_RS10960	COG0556	nucleotide-excision repair
J4N38_RS10990	COG0739	heme binding
J4N38_RS11055	COG1987	bacterial-type flagellum assembly
J4N38_RS11080	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
J4N38_RS11085	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
J4N38_RS11090	COG1516	flagellar protein fliS
J4N38_RS11105	COG1580	Controls the rotational direction of flagella during chemotaxis
J4N38_RS11110	COG1191	sigma factor activity
J4N38_RS11115	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
J4N38_RS11120	COG1360	Flagellar Motor Protein
J4N38_RS11150	COG1706	bacterial-type flagellum-dependent cell motility
J4N38_RS11155	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
J4N38_RS11160	COG4786	Flagellar basal body rod
J4N38_RS11165	COG4787	bacterial-type flagellum-dependent cell motility
J4N38_RS11170	COG1749	Flagellar hook protein flgE
J4N38_RS11175	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
J4N38_RS11180	COG1558	bacterial-type flagellum-dependent cell motility
J4N38_RS11185	COG1815	bacterial-type flagellum-dependent cell motility
J4N38_RS11205	COG0741	lytic transglycosylase activity
J4N38_RS11205	COG1388	LysM domain
J4N38_RS11210	COG4657	Part of a membrane complex involved in electron transport
J4N38_RS11220	COG4656	Part of a membrane complex involved in electron transport
J4N38_RS11225	COG4658	electron transport chain
J4N38_RS11230	COG4659	FMN binding
J4N38_RS11235	COG4660	Part of a membrane complex involved in electron transport
J4N38_RS11240	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
J4N38_RS11245	COG0346	lactoylglutathione lyase activity
J4N38_RS11265	COG2056	Na+-H+ antiporter family
J4N38_RS11270	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
J4N38_RS11280	COG2716	regulation of RNA biosynthetic process
J4N38_RS11285	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
J4N38_RS11305	COG4783	chaperone-mediated protein folding
J4N38_RS11310	COG1393	Belongs to the ArsC family
J4N38_RS11330	COG2233	PERMEase
J4N38_RS11335	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
J4N38_RS11345	COG2877	3-deoxy-8-phosphooctulonate synthase activity
J4N38_RS11350	COG2912	Transglutaminase-like superfamily
J4N38_RS11360	COG2890	protein-(glutamine-N5) methyltransferase activity
J4N38_RS11365	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
J4N38_RS11380	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
J4N38_RS11385	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
J4N38_RS11510	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
J4N38_RS11520	COG1705	Flagellar rod assembly protein muramidase FlgJ
J4N38_RS11520	COG3951	Flagellar rod assembly protein muramidase FlgJ
J4N38_RS11525	COG1706	bacterial-type flagellum-dependent cell motility
J4N38_RS11530	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
J4N38_RS11540	COG4787	bacterial-type flagellum-dependent cell motility
J4N38_RS11560	COG1815	bacterial-type flagellum-dependent cell motility
J4N38_RS11565	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
J4N38_RS11570	COG0784	Response regulator, receiver
J4N38_RS11570	COG0835	chemotaxis
J4N38_RS11580	COG2747	anti-sigma28 factor FlgM
J4N38_RS11610	COG0500	methyltransferase
J4N38_RS11635	COG2217	Heavy metal translocating P-type atpase
J4N38_RS11635	COG2608	mercury ion transmembrane transporter activity
J4N38_RS11645	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
J4N38_RS11660	COG0583	DNA-binding transcription factor activity
J4N38_RS11665	COG0301	tRNA thio-modification
J4N38_RS11665	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J4N38_RS11675	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
J4N38_RS11680	COG1722	exodeoxyribonuclease VII activity
J4N38_RS11685	COG0142	geranyltranstransferase activity
J4N38_RS11695	COG0564	pseudouridine synthase activity
J4N38_RS11700	COG3098	single-species biofilm formation
J4N38_RS11715	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J4N38_RS11735	COG0508	dehydrogenase complex catalyzes the overall conversion of
J4N38_RS11740	COG0567	Dehydrogenase, E1 component
J4N38_RS11750	COG1053	succinate dehydrogenase
J4N38_RS11755	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
J4N38_RS11770	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
J4N38_RS11780	COG0033	Phosphoglucomutase
J4N38_RS11785	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
J4N38_RS11790	COG0596	Alpha beta hydrolase
J4N38_RS11800	COG0716	FMN binding
J4N38_RS11805	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
J4N38_RS11810	COG3115	cell septum assembly
J4N38_RS11815	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
J4N38_RS11820	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
J4N38_RS11825	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4N38_RS11830	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
J4N38_RS11835	COG2190	(PTS) system
J4N38_RS11840	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J4N38_RS11845	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
J4N38_RS11850	COG1702	phosphate starvation-inducible protein PhoH
J4N38_RS11855	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
J4N38_RS11860	COG4535	Mg2 and Co2 transporter CorC
J4N38_RS11865	COG0815	Transfers the fatty acyl group on membrane lipoproteins
J4N38_RS11870	COG2888	peptidyl-tyrosine sulfation
J4N38_RS11875	COG0495	leucyl-tRNA aminoacylation
J4N38_RS11880	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
J4N38_RS11885	COG1466	dna polymerase III delta subunit
J4N38_RS11890	COG0799	negative regulation of ribosome biogenesis
J4N38_RS11895	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
J4N38_RS11900	COG0768	penicillin binding
J4N38_RS11905	COG0772	Belongs to the SEDS family
J4N38_RS11910	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
J4N38_RS11915	COG1686	Belongs to the peptidase S11 family
J4N38_RS11920	COG2921	Belongs to the UPF0250 family
J4N38_RS11930	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
J4N38_RS11945	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
J4N38_RS11955	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J4N38_RS11960	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J4N38_RS11985	COG0366	Alpha amylase catalytic
J4N38_RS11990	COG1263	PTS System
J4N38_RS11990	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J4N38_RS11995	COG1609	Transcriptional regulator
J4N38_RS12005	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
J4N38_RS12010	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
J4N38_RS12015	COG2011	ABC-type metal ion transport system permease component
J4N38_RS12020	COG1464	Belongs to the NlpA lipoprotein family
J4N38_RS12025	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
J4N38_RS12035	COG0254	rRNA binding
J4N38_RS12040	COG1720	tRNA m6t6A37 methyltransferase activity
J4N38_RS12050	COG0121	glutamine amidotransferase
J4N38_RS12055	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
J4N38_RS12060	COG1960	acyl-CoA dehydrogenase activity
J4N38_RS12075	COG0328	RNA-DNA hybrid ribonuclease activity
J4N38_RS12080	COG2226	methyltransferase
J4N38_RS12085	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J4N38_RS12090	COG0741	lytic transglycosylase activity
J4N38_RS12090	COG1388	LysM domain
J4N38_RS12100	COG3021	interspecies interaction between organisms
J4N38_RS12105	COG0347	Belongs to the P(II) protein family
J4N38_RS12120	COG0825	malonyl-CoA metabolic process
J4N38_RS12125	COG0587	DNA-directed DNA polymerase activity
J4N38_RS12130	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
J4N38_RS12135	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J4N38_RS12145	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
J4N38_RS12150	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J4N38_RS12155	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
J4N38_RS12160	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J4N38_RS12165	COG0750	zinc metalloprotease
J4N38_RS12175	COG0575	Belongs to the CDS family
J4N38_RS12180	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
J4N38_RS12185	COG0233	cytoplasmic translational termination
J4N38_RS12190	COG0528	UMP kinase activity
J4N38_RS12200	COG0052	Belongs to the universal ribosomal protein uS2 family
J4N38_RS12205	COG0024	Methionine aminopeptidase
J4N38_RS12210	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
J4N38_RS12220	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
J4N38_RS12225	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
J4N38_RS12230	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
J4N38_RS12250	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
J4N38_RS12250	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
J4N38_RS12255	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
J4N38_RS12260	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
J4N38_RS12265	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
J4N38_RS12275	COG1073	alpha beta
J4N38_RS12280	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
J4N38_RS12285	COG2252	PERMEase
J4N38_RS12290	COG2195	Cleaves the N-terminal amino acid of tripeptides
J4N38_RS12295	COG4067	protein conserved in archaea
J4N38_RS12295	COG0189	ligase activity
J4N38_RS12300	COG0189	ligase activity
J4N38_RS12310	COG0733	neurotransmitter:sodium symporter activity
J4N38_RS12325	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
J4N38_RS12330	COG0514	ATP-dependent DNA helicase (RecQ)
J4N38_RS12335	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
J4N38_RS12350	COG1477	protein flavinylation
J4N38_RS12355	COG2871	sodium ion transport
J4N38_RS12360	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
J4N38_RS12365	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
J4N38_RS12375	COG1805	sodium ion transport
J4N38_RS12380	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
J4N38_RS12385	COG0271	Belongs to the BolA IbaG family
J4N38_RS12390	COG2813	Specifically methylates the guanine in position
J4N38_RS12420	COG1595	DNA-templated transcription, initiation
J4N38_RS12435	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
J4N38_RS12440	COG0693	protein deglycase activity
J4N38_RS12445	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
J4N38_RS12450	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
J4N38_RS12460	COG0560	Phosphoserine phosphatase
J4N38_RS12470	COG0813	purine-nucleoside phosphorylase activity
J4N38_RS12475	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
J4N38_RS12480	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
J4N38_RS12495	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
J4N38_RS12500	COG0084	hydrolase, TatD family'
J4N38_RS12510	COG3022	response to hydroperoxide
J4N38_RS12515	COG1115	amino acid carrier protein
J4N38_RS12530	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
J4N38_RS12540	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
J4N38_RS12545	COG0583	DNA-binding transcription factor activity
J4N38_RS12550	COG0730	response to heat
J4N38_RS12555	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
J4N38_RS12560	COG0505	Belongs to the CarA family
J4N38_RS12570	COG0494	nUDIX hydrolase
J4N38_RS12575	COG0653	protein targeting
J4N38_RS12580	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
J4N38_RS12585	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
J4N38_RS12590	COG0849	cell division
J4N38_RS12595	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
J4N38_RS12610	COG0772	Belongs to the SEDS family
J4N38_RS12615	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
J4N38_RS12625	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
J4N38_RS12630	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
J4N38_RS12635	COG0768	penicillin binding
J4N38_RS12640	COG3116	cell division
J4N38_RS12655	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
J4N38_RS12660	COG3107	peptidoglycan biosynthetic process
J4N38_RS12665	COG0792	nuclease activity
J4N38_RS12670	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
J4N38_RS12680	COG2969	positive regulation of protein catabolic process
J4N38_RS12685	COG0625	glutathione transferase activity
J4N38_RS12690	COG2857	Cytochrome c1
J4N38_RS12695	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
J4N38_RS12700	COG0723	plastoquinol--plastocyanin reductase activity
J4N38_RS12715	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
J4N38_RS12720	COG3105	Protein conserved in bacteria
J4N38_RS12725	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J4N38_RS12730	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J4N38_RS12745	COG3150	esterase
J4N38_RS12755	COG3151	Protein conserved in bacteria
J4N38_RS12760	COG0494	nUDIX hydrolase
J4N38_RS12765	COG1538	Outer membrane efflux protein
J4N38_RS12775	COG0784	Response regulator, receiver
J4N38_RS12775	COG2198	Histidine kinase
J4N38_RS12775	COG5002	protein histidine kinase activity
J4N38_RS12780	COG5001	Diguanylate cyclase
J4N38_RS12780	COG4251	negative regulation of phosphorylation
J4N38_RS12780	COG3706	GGDEF domain
J4N38_RS12780	COG2203	Gaf domain
J4N38_RS12785	COG1242	4 iron, 4 sulfur cluster binding
J4N38_RS12790	COG0069	glutamate synthase activity
J4N38_RS12790	COG0070	glutamate synthase
J4N38_RS12790	COG0067	glutamate synthase
J4N38_RS12800	COG0067	glutamate synthase
J4N38_RS12800	COG0069	glutamate synthase activity
J4N38_RS12800	COG0070	glutamate synthase
J4N38_RS12805	COG0493	'glutamate synthase
J4N38_RS12830	COG0195	Participates in both transcription termination and antitermination
J4N38_RS12835	COG0779	Required for maturation of 30S ribosomal subunits
J4N38_RS12910	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
J4N38_RS12915	COG3153	acetyltransferase
J4N38_RS12920	COG3154	lipid carrier protein
J4N38_RS12930	COG0826	peptidase U32
J4N38_RS12935	COG0826	peptidase U32
J4N38_RS12940	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
J4N38_RS12960	COG0513	Belongs to the DEAD box helicase family
J4N38_RS12975	COG0456	acetyltransferase
J4N38_RS12985	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
J4N38_RS12990	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
J4N38_RS12995	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
J4N38_RS13000	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
J4N38_RS13005	COG1534	Rna-binding protein
J4N38_RS13010	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
J4N38_RS13015	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
J4N38_RS13030	COG0316	Belongs to the HesB IscA family
J4N38_RS13040	COG0628	permease
J4N38_RS13045	COG2813	Specifically methylates the guanine in position
J4N38_RS13050	COG2205	protein histidine kinase activity
J4N38_RS13050	COG0784	Response regulator, receiver
J4N38_RS13050	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J4N38_RS13050	COG2198	Histidine kinase
J4N38_RS13055	COG0747	negative chemotaxis
J4N38_RS13070	COG0444	Belongs to the ABC transporter superfamily
J4N38_RS13075	COG4608	Belongs to the ABC transporter superfamily
J4N38_RS13085	COG2971	BadF BadG BcrA BcrD
J4N38_RS13100	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
J4N38_RS13105	COG3842	ATPase activity
J4N38_RS13115	COG1840	ABC-type Fe3 transport system, periplasmic component
J4N38_RS13120	COG0004	ammonium transporteR
J4N38_RS13130	COG3112	Uncharacterised protein family (UPF0231)
J4N38_RS13135	COG1049	propionate catabolic process, 2-methylcitrate cycle
J4N38_RS13140	COG1752	Esterase of the alpha-beta hydrolase superfamily
J4N38_RS13145	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J4N38_RS13230	COG3119	arylsulfatase activity
J4N38_RS13235	COG1309	transcriptional regulator
J4N38_RS13265	COG1643	Atp-dependent helicase
J4N38_RS13275	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
J4N38_RS13290	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
J4N38_RS13295	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
J4N38_RS13305	COG0842	Transport permease protein
J4N38_RS13310	COG1131	(ABC) transporter
J4N38_RS13315	COG0659	secondary active sulfate transmembrane transporter activity
J4N38_RS13320	COG0288	reversible hydration of carbon dioxide
J4N38_RS13335	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J4N38_RS13340	COG0508	dehydrogenase complex catalyzes the overall conversion of
J4N38_RS13345	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
J4N38_RS13350	COG2186	Transcriptional regulator
J4N38_RS13355	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
J4N38_RS13360	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
J4N38_RS13365	COG4974	Belongs to the 'phage' integrase family
J4N38_RS13370	COG0716	FMN binding
J4N38_RS13380	COG0157	Belongs to the NadC ModD family
J4N38_RS13385	COG4969	Belongs to the N-Me-Phe pilin family
J4N38_RS13390	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
J4N38_RS13395	COG1459	type II secretion system
J4N38_RS13405	COG0237	dephospho-CoA kinase activity
J4N38_RS13410	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
J4N38_RS13415	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
J4N38_RS13425	COG0336	Belongs to the RNA methyltransferase TrmD family
J4N38_RS13435	COG0228	four-way junction DNA binding
J4N38_RS13440	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
J4N38_RS13445	COG4137	Cytochrome C assembly protein
J4N38_RS13450	COG4536	flavin adenine dinucleotide binding
J4N38_RS13455	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
J4N38_RS13460	COG1388	LysM domain
J4N38_RS13460	COG4942	peptidase
J4N38_RS13470	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
J4N38_RS13475	COG0585	pseudouridine synthase activity
J4N38_RS13480	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
J4N38_RS13485	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
J4N38_RS13490	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
J4N38_RS13495	COG1968	undecaprenyl-diphosphatase activity
J4N38_RS13500	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
J4N38_RS13505	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
J4N38_RS13510	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
J4N38_RS13515	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
J4N38_RS13520	COG3385	transposase activity
J4N38_RS13525	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
J4N38_RS13530	COG0828	Belongs to the bacterial ribosomal protein bS21 family
J4N38_RS13535	COG1610	YqeY-like protein
J4N38_RS13540	COG0358	DNA primase activity
J4N38_RS13555	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
J4N38_RS13560	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
J4N38_RS13565	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J4N38_RS13570	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
J4N38_RS13575	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
J4N38_RS13585	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
J4N38_RS13590	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
J4N38_RS13595	COG3610	response to peptide
J4N38_RS13600	COG2966	Psort location CytoplasmicMembrane, score
J4N38_RS13605	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
J4N38_RS13615	COG0261	This protein binds to 23S rRNA in the presence of protein L20
J4N38_RS13620	COG0142	geranyltranstransferase activity
J4N38_RS13670	COG3437	response regulator, receiver
J4N38_RS13685	COG0270	DNA (cytosine-5-)-methyltransferase activity
J4N38_RS13715	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
J4N38_RS13780	COG1854	S-ribosylhomocysteine lyase activity
J4N38_RS13795	COG0612	Peptidase, M16
J4N38_RS13800	COG1238	metal cluster binding
J4N38_RS13810	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
J4N38_RS13815	COG0511	ligase activity, forming carbon-carbon bonds
J4N38_RS13815	COG5016	pyruvate
J4N38_RS13820	COG3630	sodium ion export across plasma membrane
J4N38_RS13885	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
J4N38_RS13890	COG1546	Belongs to the CinA family
J4N38_RS13895	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
J4N38_RS13900	COG0795	lipopolysaccharide-transporting ATPase activity
J4N38_RS13905	COG0795	lipopolysaccharide-transporting ATPase activity
J4N38_RS13915	COG2927	DNA polymerase III (CHI subunit)
J4N38_RS13920	COG0525	valine-tRNA ligase activity
J4N38_RS13930	COG4269	membrane
J4N38_RS13940	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
J4N38_RS13945	COG0564	pseudouridine synthase activity
J4N38_RS13960	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
J4N38_RS13975	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
J4N38_RS13980	COG0251	oxidation-reduction process
J4N38_RS13990	COG0039	L-malate dehydrogenase activity
J4N38_RS13995	COG1438	arginine binding
J4N38_RS14000	COG2358	TRAP transporter, solute receptor (TAXI family
J4N38_RS14010	COG0589	response to stress
J4N38_RS14035	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
J4N38_RS14040	COG0527	aspartate kinase activity
J4N38_RS14045	COG0312	modulator of DNA gyrase
J4N38_RS14050	COG3028	Belongs to the UPF0307 family
J4N38_RS14055	COG0204	Acyl-transferase
J4N38_RS14060	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
J4N38_RS14065	COG5007	Belongs to the BolA IbaG family
J4N38_RS14075	COG2854	intermembrane phospholipid transfer
J4N38_RS14080	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
J4N38_RS14085	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
J4N38_RS14090	COG1127	ABC transporter
J4N38_RS14100	COG0517	IMP dehydrogenase activity
J4N38_RS14100	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
J4N38_RS14105	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
J4N38_RS14115	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
J4N38_RS14120	COG1137	ATPase activity
J4N38_RS14130	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
J4N38_RS14135	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4N38_RS14140	COG1660	Displays ATPase and GTPase activities
J4N38_RS14145	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4N38_RS14150	COG2239	Acts as a magnesium transporter
J4N38_RS14155	COG1410	methionine synthase
J4N38_RS14155	COG0646	methionine synthase
J4N38_RS14225	COG0175	sulfate reduction
J4N38_RS14230	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
J4N38_RS14235	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
J4N38_RS14260	COG3437	response regulator, receiver
J4N38_RS14265	COG0784	Response regulator, receiver
J4N38_RS14265	COG2205	protein histidine kinase activity
J4N38_RS14265	COG5002	protein histidine kinase activity
J4N38_RS14270	COG0735	belongs to the Fur family
J4N38_RS14280	COG0529	Catalyzes the synthesis of activated sulfate
J4N38_RS14285	COG0471	metal ion transport
J4N38_RS14285	COG3273	potassium ion transport
J4N38_RS14300	COG1648	precorrin-2 dehydrogenase activity
J4N38_RS14300	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
J4N38_RS14305	COG0737	Belongs to the 5'-nucleotidase family
J4N38_RS14315	COG2153	protein acetylation
J4N38_RS14330	COG0545	Peptidyl-prolyl cis-trans isomerase
J4N38_RS14340	COG0203	ribosomal protein L17
J4N38_RS14345	COG0202	RNA polymerase activity
J4N38_RS14355	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
J4N38_RS14360	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
J4N38_RS14365	COG0257	Belongs to the bacterial ribosomal protein bL36 family
J4N38_RS14370	COG0201	protein transport
J4N38_RS14375	COG0200	Binds to the 23S rRNA
J4N38_RS14380	COG1841	ribosomal large subunit assembly
J4N38_RS14395	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
J4N38_RS14400	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
J4N38_RS14410	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
J4N38_RS14425	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
J4N38_RS14440	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
J4N38_RS14445	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
J4N38_RS14450	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
J4N38_RS14465	COG0088	Forms part of the polypeptide exit tunnel
J4N38_RS14470	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
J4N38_RS14475	COG0051	transcription antitermination factor activity, RNA binding
J4N38_RS14480	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J4N38_RS14485	COG0557	exoribonuclease II activity
J4N38_RS14490	COG0402	S-adenosylhomocysteine deaminase activity
J4N38_RS14495	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
J4N38_RS14500	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
J4N38_RS14510	COG1047	Peptidyl-prolyl cis-trans
J4N38_RS14525	COG2249	NAD(P)H dehydrogenase (quinone) activity
J4N38_RS14530	COG0488	(ABC) transporter
J4N38_RS14540	COG0429	hydrolase of the alpha beta-hydrolase fold
J4N38_RS14545	COG3089	Belongs to the UPF0270 family
J4N38_RS14550	COG3954	Phosphoribulokinase
J4N38_RS14555	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J4N38_RS14560	COG0490	domain, Protein
J4N38_RS14560	COG0471	metal ion transport
J4N38_RS14575	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
J4N38_RS14580	COG4942	peptidase
J4N38_RS14600	COG2816	NAD+ diphosphatase activity
J4N38_RS14605	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
J4N38_RS14610	COG1288	antiporter activity
J4N38_RS14625	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
J4N38_RS14630	COG0540	Belongs to the ATCase OTCase family
J4N38_RS14635	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
J4N38_RS14640	COG1438	arginine binding
J4N38_RS14645	COG4232	protein-disulfide reductase activity
J4N38_RS14655	COG2095	MarC family integral membrane protein
J4N38_RS14665	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J4N38_RS14685	COG0149	triose-phosphate isomerase activity
J4N38_RS14690	COG0534	Mate efflux family protein
J4N38_RS14695	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
J4N38_RS14700	COG1575	Belongs to the MenA family. Type 1 subfamily
J4N38_RS14705	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
J4N38_RS14710	COG1509	lysine 2,3-aminomutase activity
J4N38_RS14720	COG1285	pathogenesis
J4N38_RS14730	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
J4N38_RS14740	COG0745	RESPONSE REGULATOR receiver
J4N38_RS14745	COG2205	protein histidine kinase activity
J4N38_RS14750	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
J4N38_RS14755	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
J4N38_RS14760	COG0180	Tryptophanyl-tRNA synthetase
J4N38_RS14765	COG0546	phosphoglycolate phosphatase activity
J4N38_RS14770	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
J4N38_RS14775	COG0338	D12 class N6 adenine-specific DNA methyltransferase
J4N38_RS14785	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
J4N38_RS14820	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
J4N38_RS14830	COG0678	peroxiredoxin activity
J4N38_RS14830	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
J4N38_RS14835	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J4N38_RS14840	COG0251	oxidation-reduction process
J4N38_RS14850	COG0165	Argininosuccinate lyase
J4N38_RS14850	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
J4N38_RS14855	COG0137	argininosuccinate synthase activity
J4N38_RS14860	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
J4N38_RS14865	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
J4N38_RS14935	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
J4N38_RS14945	COG4206	TonB-dependent receptor
J4N38_RS14965	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J4N38_RS14970	COG0534	Mate efflux family protein
J4N38_RS14980	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
J4N38_RS14985	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
J4N38_RS14990	COG2937	Belongs to the GPAT DAPAT family
J4N38_RS14995	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
J4N38_RS15000	COG3161	chorismate lyase activity
J4N38_RS15005	COG1580	Controls the rotational direction of flagella during chemotaxis
J4N38_RS15010	COG0705	Rhomboid family
J4N38_RS15015	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J4N38_RS15020	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
J4N38_RS15025	COG2177	Part of the ABC transporter FtsEX involved in
J4N38_RS15030	COG2884	Cell division ATP-binding protein ftsE
J4N38_RS15035	COG0552	protein localization to endoplasmic reticulum
J4N38_RS15040	COG0742	ribosomal rna small subunit methyltransferase
J4N38_RS15050	COG2095	MarC family integral membrane protein
J4N38_RS15095	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
J4N38_RS15100	COG0640	Transcriptional regulator
J4N38_RS15105	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
J4N38_RS15110	COG1280	lysine exporter protein (LysE YggA)
J4N38_RS15115	COG2267	carboxylic ester hydrolase activity
J4N38_RS15120	COG0561	phosphatase activity
J4N38_RS15135	COG3148	PFAM DTW domain containing protein
J4N38_RS15140	COG1011	Hydrolase
J4N38_RS15155	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
J4N38_RS15160	COG0019	diaminopimelate decarboxylase activity
J4N38_RS15170	COG1965	Belongs to the frataxin family
J4N38_RS15175	COG3072	Adenylate cyclase
J4N38_RS15180	COG0181	hydroxymethylbilane synthase activity
J4N38_RS15185	COG1587	Uroporphyrinogen-III synthase
J4N38_RS15190	COG2959	enzyme of heme biosynthesis
J4N38_RS15195	COG3071	HemY protein
J4N38_RS15230	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
J4N38_RS15245	COG3118	belongs to the thioredoxin family
J4N38_RS15255	COG0248	Ppx GppA phosphatase
J4N38_RS15260	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
J4N38_RS15270	COG0514	ATP-dependent DNA helicase (RecQ)
J4N38_RS15275	COG2962	Rard protein
J4N38_RS15285	COG1280	lysine exporter protein (LysE YggA)
J4N38_RS15290	COG0405	Gamma-glutamyltransferase
J4N38_RS15295	COG0210	DNA helicase
J4N38_RS15305	COG3220	belongs to the UPF0276 family
J4N38_RS15325	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
J4N38_RS15330	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J4N38_RS15345	COG0644	oxidoreductase
J4N38_RS15355	COG3527	Alpha-acetolactate decarboxylase
J4N38_RS15370	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4N38_RS15375	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4N38_RS15385	COG2207	Transcriptional regulator
J4N38_RS15390	COG3537	Alpha-1,2-mannosidase
J4N38_RS15400	COG3537	Alpha-1,2-mannosidase
J4N38_RS15405	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4N38_RS15410	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4N38_RS15410	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4N38_RS15410	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4N38_RS15430	COG0477	Major facilitator Superfamily
J4N38_RS15450	COG2197	response regulator
J4N38_RS15465	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J4N38_RS15470	COG0601	transmembrane transport
J4N38_RS15515	COG0210	DNA helicase
J4N38_RS15520	COG1309	transcriptional regulator
J4N38_RS15525	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J4N38_RS15530	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J4N38_RS15535	COG2960	long-chain fatty acid transporting porin activity
J4N38_RS15540	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
J4N38_RS15545	COG0583	DNA-binding transcription factor activity
J4N38_RS15550	COG0635	Involved in the biosynthesis of porphyrin-containing compound
J4N38_RS15580	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J4N38_RS15580	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J4N38_RS15595	COG0084	hydrolase, TatD family'
J4N38_RS15600	COG0805	protein transport
J4N38_RS15605	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
J4N38_RS15610	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
J4N38_RS15615	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
J4N38_RS15625	COG2226	methyltransferase
J4N38_RS15630	COG1322	Protein conserved in bacteria
J4N38_RS15640	COG1639	'signal transduction protein
J4N38_RS15660	COG2081	HI0933 family
J4N38_RS15670	COG1528	Iron-storage protein
J4N38_RS15675	COG0589	response to stress
J4N38_RS15690	COG0742	ribosomal rna small subunit methyltransferase
J4N38_RS15695	COG5001	Diguanylate cyclase
J4N38_RS15695	COG5002	protein histidine kinase activity
J4N38_RS15700	COG1522	sequence-specific DNA binding
J4N38_RS15720	COG0006	proline dipeptidase activity
J4N38_RS15720	COG0006	proline dipeptidase activity
J4N38_RS15730	COG2022	thiamine diphosphate biosynthetic process
J4N38_RS15740	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
J4N38_RS15745	COG0352	thiamine-phosphate diphosphorylase activity
J4N38_RS15760	COG2132	Multicopper oxidase
J4N38_RS15805	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
J4N38_RS15810	COG1739	Uncharacterized protein family UPF0029
J4N38_RS15820	COG0183	Belongs to the thiolase family
J4N38_RS15825	COG0583	DNA-binding transcription factor activity
J4N38_RS15830	COG2814	Major facilitator Superfamily
J4N38_RS15840	COG0765	amino acid transport
J4N38_RS15850	COG0355	proton-transporting ATP synthase activity, rotational mechanism
J4N38_RS15855	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
J4N38_RS15860	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
J4N38_RS15865	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
J4N38_RS15870	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
J4N38_RS15875	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
J4N38_RS15890	COG3312	ion transport
J4N38_RS15895	COG1475	DNA binding
J4N38_RS15900	COG1192	Involved in chromosome partitioning
J4N38_RS15905	COG0357	Ribosomal RNA small subunit methyltransferase G
J4N38_RS15910	COG0445	tRNA wobble uridine modification
J4N38_RS15915	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
J4N38_RS15925	COG0706	membrane insertase activity
J4N38_RS15940	COG0230	Belongs to the bacterial ribosomal protein bL34 family
J4N38_RS15945	COG1126	abc transporter atp-binding protein
J4N38_RS15970	COG1444	tRNA N-acetyltransferase activity
J4N38_RS15985	COG0643	Histidine kinase
J4N38_RS15985	COG2198	Histidine kinase
J4N38_RS15995	COG0835	chemotaxis
J4N38_RS16000	COG0840	transmembrane signaling receptor activity
J4N38_RS16005	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
J4N38_RS16055	COG0583	DNA-binding transcription factor activity
J4N38_RS16060	COG1175	transmembrane transport
J4N38_RS16080	COG0546	phosphoglycolate phosphatase activity
J4N38_RS16085	COG3842	ATPase activity
J4N38_RS16090	COG0589	response to stress
J4N38_RS16095	COG2723	6-phospho-beta-galactosidase activity
J4N38_RS16125	COG0583	DNA-binding transcription factor activity
J4N38_RS16140	COG0351	phosphomethylpyrimidine kinase
J4N38_RS16145	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
J4N38_RS16155	COG0730	response to heat
J4N38_RS16165	COG4977	sequence-specific DNA binding
J4N38_RS16180	COG0671	phosphoesterase, PA-phosphatase related
J4N38_RS16225	COG0697	spore germination
J4N38_RS16260	COG0471	metal ion transport
J4N38_RS16270	COG2814	Major facilitator Superfamily
J4N38_RS16275	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
J4N38_RS16320	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
J4N38_RS16335	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
J4N38_RS16345	COG2207	Transcriptional regulator
J4N38_RS16360	COG4999	Histidine kinase
J4N38_RS16360	COG3850	Histidine kinase
J4N38_RS16360	COG3437	response regulator, receiver
J4N38_RS16360	COG2205	protein histidine kinase activity
J4N38_RS16365	COG0402	S-adenosylhomocysteine deaminase activity
J4N38_RS16375	COG1529	Aldehyde oxidase and xanthine dehydrogenase
J4N38_RS16385	COG2186	Transcriptional regulator
J4N38_RS16395	COG0402	S-adenosylhomocysteine deaminase activity
J4N38_RS16400	COG1404	Belongs to the peptidase S8 family
J4N38_RS16430	COG0456	acetyltransferase
J4N38_RS16445	COG2909	trisaccharide binding
J4N38_RS16450	COG0058	SHG alpha-glucan phosphorylase activity
J4N38_RS16455	COG1640	4-alpha-glucanotransferase
J4N38_RS16460	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
J4N38_RS16480	COG1472	Belongs to the glycosyl hydrolase 3 family
J4N38_RS16485	COG3876	Protein conserved in bacteria
J4N38_RS16500	COG3293	Transposase
J4N38_RS16550	COG0561	phosphatase activity
J4N38_RS16570	COG0488	(ABC) transporter
J4N38_RS16595	COG1733	regulation of RNA biosynthetic process
J4N38_RS16600	COG0456	acetyltransferase
J4N38_RS16605	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
J4N38_RS16610	COG0662	Cupin 2, conserved barrel domain protein
J4N38_RS16615	COG0527	aspartate kinase activity
J4N38_RS16635	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4N38_RS16635	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4N38_RS16635	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
J4N38_RS16640	COG0383	alpha-mannosidase activity
J4N38_RS16650	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4N38_RS16650	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4N38_RS16650	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4N38_RS16670	COG0113	porphobilinogen synthase activity
J4N38_RS16675	COG0183	Belongs to the thiolase family
J4N38_RS16685	COG3246	L-lysine catabolic process to acetate
J4N38_RS16715	COG0583	DNA-binding transcription factor activity
J4N38_RS16720	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
J4N38_RS16730	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
J4N38_RS16735	COG4999	Histidine kinase
J4N38_RS16735	COG3437	response regulator, receiver
J4N38_RS16735	COG2205	protein histidine kinase activity
J4N38_RS16735	COG3850	Histidine kinase
J4N38_RS16745	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
J4N38_RS16775	COG0657	acetylesterase activity
J4N38_RS16785	COG3448	diguanylate cyclase activity
J4N38_RS16785	COG4175	Glycine betaine
J4N38_RS16790	COG4176	ABC-type proline glycine betaine transport system permease component
J4N38_RS16810	COG2095	MarC family integral membrane protein
J4N38_RS16820	COG0583	DNA-binding transcription factor activity
J4N38_RS16845	COG4964	Belongs to the GSP D family
J4N38_RS16855	COG2894	cell division
J4N38_RS16910	COG1477	protein flavinylation
J4N38_RS16925	COG0840	transmembrane signaling receptor activity
J4N38_RS16935	COG0573	inorganic phosphate transmembrane transporter activity
J4N38_RS16940	COG0581	inorganic phosphate transmembrane transporter activity
J4N38_RS16945	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
J4N38_RS16960	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
J4N38_RS16965	COG1162	GTPase activity
J4N38_RS16975	COG0363	glucosamine-6-phosphate deaminase activity
J4N38_RS16995	COG0454	-acetyltransferase
J4N38_RS17020	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J4N38_RS17030	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J4N38_RS17035	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
J4N38_RS17040	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
J4N38_RS17055	COG3655	Transcriptional regulator
J4N38_RS17065	COG0137	argininosuccinate synthase activity
J4N38_RS17080	COG3608	succinylglutamate desuccinylase aspartoacylase
J4N38_RS17100	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J4N38_RS17110	COG3314	Sporulation integral membrane protein YlbJ
J4N38_RS17115	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
J4N38_RS17120	COG1151	hydroxylamine reductase activity
J4N38_RS17130	COG0583	DNA-binding transcription factor activity
J4N38_RS17145	COG3604	Transcriptional regulator
J4N38_RS17175	COG3046	protein related to deoxyribodipyrimidine photolyase
J4N38_RS17185	COG2329	Antibiotic biosynthesis monooxygenase
J4N38_RS17190	COG3304	Inner membrane component domain
J4N38_RS17200	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J4N38_RS17255	COG0004	ammonium transporteR
J4N38_RS17265	COG3383	formate dehydrogenase (NAD+) activity
J4N38_RS17275	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J4N38_RS17295	COG0739	heme binding
J4N38_RS17300	COG3047	cAMP biosynthetic process
J4N38_RS17340	COG2271	Major facilitator Superfamily
J4N38_RS17345	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J4N38_RS17365	COG0431	NADPH-dependent FMN reductase
J4N38_RS17370	COG0697	spore germination
J4N38_RS17395	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
J4N38_RS17395	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
J4N38_RS17400	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
J4N38_RS17400	COG2207	Transcriptional regulator
J4N38_RS17405	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J4N38_RS17410	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J4N38_RS17420	COG1522	sequence-specific DNA binding
J4N38_RS17430	COG0840	transmembrane signaling receptor activity
J4N38_RS17440	COG1357	PFAM Pentapeptide repeats (8 copies)
J4N38_RS17460	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
J4N38_RS17475	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J4N38_RS17485	COG1309	transcriptional regulator
J4N38_RS17500	COG0745	RESPONSE REGULATOR receiver
J4N38_RS17505	COG5002	protein histidine kinase activity
J4N38_RS17565	COG1054	Belongs to the UPF0176 family
J4N38_RS17580	COG1028	Short-chain dehydrogenase reductase Sdr
J4N38_RS17605	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J4N38_RS17615	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
J4N38_RS17635	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
J4N38_RS17645	COG1733	regulation of RNA biosynthetic process
J4N38_RS17660	COG3795	YCII-related domain
J4N38_RS17665	COG4941	Belongs to the sigma-70 factor family
J4N38_RS17670	COG0625	glutathione transferase activity
J4N38_RS17675	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J4N38_RS17680	COG0366	Alpha amylase catalytic
J4N38_RS17700	COG2084	Dehydrogenase
J4N38_RS17715	COG2130	NADP-dependent
J4N38_RS17720	COG1309	transcriptional regulator
J4N38_RS17735	COG3097	Belongs to the UPF0267 family
J4N38_RS17740	COG0513	Belongs to the DEAD box helicase family
J4N38_RS17750	COG1228	amidohydrolase
J4N38_RS17775	COG1175	transmembrane transport
J4N38_RS17780	COG0395	ABC-type sugar transport system, permease component
J4N38_RS17785	COG1554	hydrolase, family 65, central catalytic
J4N38_RS17790	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J4N38_RS17795	COG3842	ATPase activity
J4N38_RS17805	COG1621	beta-fructofuranosidase activity
J4N38_RS17815	COG1609	Transcriptional regulator
J4N38_RS17840	COG3842	ATPase activity
J4N38_RS17845	COG1472	Belongs to the glycosyl hydrolase 3 family
J4N38_RS17860	COG0110	maltose O-acetyltransferase activity
J4N38_RS17885	COG2356	endonuclease I
J4N38_RS17900	COG0564	pseudouridine synthase activity
J4N38_RS17920	COG0583	DNA-binding transcription factor activity
J4N38_RS17925	COG2814	Major facilitator Superfamily
J4N38_RS17950	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
J4N38_RS17960	COG0291	Belongs to the bacterial ribosomal protein bL35 family
J4N38_RS17965	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
J4N38_RS17970	COG0579	oxidoreductase
J4N38_RS17990	COG1012	belongs to the aldehyde dehydrogenase family
J4N38_RS17995	COG3284	Transcriptional regulator
J4N38_RS18020	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
J4N38_RS18025	COG0363	glucosamine-6-phosphate deaminase activity
J4N38_RS18030	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
J4N38_RS18035	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
J4N38_RS18045	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
J4N38_RS18055	COG2271	Major facilitator Superfamily
J4N38_RS18060	COG3851	Histidine kinase
J4N38_RS18065	COG2197	response regulator
J4N38_RS18085	COG0418	dihydroorotase activity
J4N38_RS18090	COG0633	Ferredoxin
J4N38_RS18090	COG3217	Mosc domain protein beta barrel domain protein
J4N38_RS18090	COG3217	Mosc domain protein beta barrel domain protein
J4N38_RS18090	COG0633	Ferredoxin
J4N38_RS18100	COG1349	DNA-binding transcription factor activity
J4N38_RS18120	COG2354	Protein conserved in bacteria
J4N38_RS18130	COG0366	Alpha amylase catalytic
J4N38_RS18155	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
J4N38_RS18170	COG0739	heme binding
J4N38_RS18185	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
J4N38_RS18190	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J4N38_RS18200	COG0848	biopolymer transport protein
J4N38_RS18205	COG0811	peptide transport
J4N38_RS18210	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
J4N38_RS18220	COG3721	Heme iron utilization protein
J4N38_RS18225	COG0748	coenzyme F420 binding
J4N38_RS18230	COG2096	Adenosyltransferase
J4N38_RS18235	COG3842	ATPase activity
J4N38_RS18245	COG1175	transmembrane transport
J4N38_RS18250	COG3833	ABC-type maltose transport systems, permease component
J4N38_RS18260	COG4533	DNA binding
J4N38_RS18300	COG0784	Response regulator, receiver
J4N38_RS18300	COG5002	protein histidine kinase activity
J4N38_RS18300	COG2205	protein histidine kinase activity
J4N38_RS18310	COG0861	Integral membrane protein TerC family
J4N38_RS18315	COG0402	S-adenosylhomocysteine deaminase activity
J4N38_RS18320	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
J4N38_RS18325	COG1566	PFAM secretion protein HlyD family protein
J4N38_RS18350	COG0745	RESPONSE REGULATOR receiver
J4N38_RS18370	COG0121	glutamine amidotransferase
J4N38_RS18375	COG0531	amino acid
J4N38_RS18395	COG0673	inositol 2-dehydrogenase activity
J4N38_RS18400	COG1765	OsmC-like protein
J4N38_RS18405	COG3385	transposase activity
J4N38_RS18410	COG0110	maltose O-acetyltransferase activity
J4N38_RS18435	COG2304	oxidoreductase activity
J4N38_RS18440	COG2304	oxidoreductase activity
J4N38_RS18455	COG0714	Associated with various cellular activities
J4N38_RS18485	COG5002	protein histidine kinase activity
J4N38_RS18490	COG0745	RESPONSE REGULATOR receiver
J4N38_RS18500	COG0745	RESPONSE REGULATOR receiver
J4N38_RS18505	COG2205	protein histidine kinase activity
J4N38_RS18510	COG4452	Inner membrane protein CreD
J4N38_RS18515	COG0346	lactoylglutathione lyase activity
J4N38_RS18525	COG0156	8-amino-7-oxononanoate synthase activity
J4N38_RS18530	COG1063	alcohol dehydrogenase
J4N38_RS18545	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
J4N38_RS18550	COG2195	Cleaves the N-terminal amino acid of tripeptides
J4N38_RS18575	COG2205	protein histidine kinase activity
J4N38_RS18575	COG0784	Response regulator, receiver
J4N38_RS18580	COG2205	protein histidine kinase activity
J4N38_RS18580	COG0784	Response regulator, receiver
J4N38_RS18585	COG5002	protein histidine kinase activity
J4N38_RS18585	COG2205	protein histidine kinase activity
J4N38_RS18585	COG0784	Response regulator, receiver
J4N38_RS18600	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
J4N38_RS18605	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
J4N38_RS18610	COG3186	Phenylalanine-4-hydroxylase
J4N38_RS18650	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J4N38_RS18655	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J4N38_RS18680	COG1454	alcohol dehydrogenase
J4N38_RS18685	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
J4N38_RS18700	COG1011	Hydrolase
J4N38_RS18730	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
J4N38_RS18735	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
J4N38_RS18740	COG1840	ABC-type Fe3 transport system, periplasmic component
J4N38_RS18745	COG3842	ATPase activity
J4N38_RS18770	COG2866	Carboxypeptidase
J4N38_RS18775	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J4N38_RS18780	COG0583	DNA-binding transcription factor activity
J4N38_RS18785	COG1760	l-serine dehydratase
J4N38_RS18805	COG3706	GGDEF domain
J4N38_RS18810	COG0784	Response regulator, receiver
J4N38_RS18810	COG0835	chemotaxis
J4N38_RS18815	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J4N38_RS18835	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
J4N38_RS18840	COG0494	nUDIX hydrolase
J4N38_RS18845	COG0714	Associated with various cellular activities
J4N38_RS18850	COG2425	protein containing a von Willebrand factor type A (vWA) domain
J4N38_RS18870	COG3706	GGDEF domain
J4N38_RS18875	COG1846	Transcriptional regulator
J4N38_RS18880	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
J4N38_RS18905	COG3048	D-serine ammonia-lyase activity
J4N38_RS18925	COG0814	amino acid
J4N38_RS18935	COG0513	Belongs to the DEAD box helicase family
J4N38_RS18940	COG0840	transmembrane signaling receptor activity
J4N38_RS18945	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J4N38_RS18950	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J4N38_RS18965	COG0546	phosphoglycolate phosphatase activity
J4N38_RS18980	COG0243	molybdopterin cofactor binding
J4N38_RS18985	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
J4N38_RS18985	COG1648	precorrin-2 dehydrogenase activity
J4N38_RS18990	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
J4N38_RS19000	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
J4N38_RS19000	COG1116	anion transmembrane transporter activity
J4N38_RS19005	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J4N38_RS19010	COG1116	anion transmembrane transporter activity
J4N38_RS19015	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
J4N38_RS19015	COG2146	nitrite reductase [NAD(P)H] activity
J4N38_RS19020	COG2146	nitrite reductase [NAD(P)H] activity
J4N38_RS19025	COG1858	cytochrome C peroxidase
J4N38_RS19050	COG3118	belongs to the thioredoxin family
J4N38_RS19055	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
J4N38_RS19060	COG0420	3'-5' exonuclease activity
J4N38_RS19065	COG0419	ATPase involved in DNA repair
J4N38_RS19070	COG0784	Response regulator, receiver
J4N38_RS19070	COG2205	protein histidine kinase activity
J4N38_RS19075	COG0156	8-amino-7-oxononanoate synthase activity
J4N38_RS19085	COG0038	chloride channel
J4N38_RS19090	COG0523	cobalamin synthesis protein
J4N38_RS19095	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
J4N38_RS19120	COG1522	sequence-specific DNA binding
J4N38_RS19125	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
J4N38_RS19130	COG1072	(Pantothenic acid kinase))
J4N38_RS19140	COG1063	alcohol dehydrogenase
J4N38_RS19145	COG2213	PTS system mannitol-specific
J4N38_RS19150	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4N38_RS19155	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
J4N38_RS19160	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
J4N38_RS19170	COG0583	DNA-binding transcription factor activity
J4N38_RS19185	COG2897	thiosulfate sulfurtransferase activity
J4N38_RS19190	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
J4N38_RS19205	COG0513	Belongs to the DEAD box helicase family
J4N38_RS19210	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J4N38_RS19210	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J4N38_RS19240	COG3293	Transposase
J4N38_RS19245	COG0800	Aldolase
J4N38_RS19250	COG1803	Methylglyoxal synthase
J4N38_RS19255	COG1879	ABC-type sugar transport system periplasmic component
J4N38_RS19260	COG2205	protein histidine kinase activity
J4N38_RS19260	COG2198	Histidine kinase
J4N38_RS19260	COG0784	Response regulator, receiver
J4N38_RS19270	COG1979	alcohol dehydrogenase
J4N38_RS19275	COG2207	Transcriptional regulator
J4N38_RS19280	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
J4N38_RS19290	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
J4N38_RS19290	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4N38_RS19290	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4N38_RS19295	COG1105	Belongs to the carbohydrate kinase PfkB family
J4N38_RS19300	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4N38_RS19300	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4N38_RS19305	COG1609	Transcriptional regulator
J4N38_RS19320	COG1492	cobalamin metabolic process
J4N38_RS19325	COG0725	ABC transporter, periplasmic molybdate-binding protein
J4N38_RS19330	COG4149	molybdate abc transporter
J4N38_RS19335	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
J4N38_RS19345	COG5001	Diguanylate cyclase
J4N38_RS19345	COG4251	negative regulation of phosphorylation
J4N38_RS19345	COG2203	Gaf domain
J4N38_RS19345	COG3706	GGDEF domain
J4N38_RS19350	COG3706	GGDEF domain
J4N38_RS19365	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
J4N38_RS19370	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
J4N38_RS19380	COG0745	RESPONSE REGULATOR receiver
J4N38_RS19395	COG3140	Belongs to the UPF0181 family
J4N38_RS19415	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
J4N38_RS19450	COG0023	Translation Initiation Factor
J4N38_RS19470	COG3266	domain, Protein
J4N38_RS19475	COG1042	CoA-binding domain protein
J4N38_RS19475	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J4N38_RS19475	COG0045	succinate-CoA ligase (ADP-forming) activity
J4N38_RS19480	COG0583	DNA-binding transcription factor activity
J4N38_RS19485	COG4771	TonB-dependent receptor
J4N38_RS19485	COG1629	transport
J4N38_RS19490	COG0840	transmembrane signaling receptor activity
J4N38_RS19510	COG3706	GGDEF domain
J4N38_RS19530	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
J4N38_RS19535	COG1028	Short-chain dehydrogenase reductase Sdr
J4N38_RS19545	COG1024	Enoyl-CoA hydratase
J4N38_RS19550	COG1024	Enoyl-CoA hydratase
J4N38_RS19565	COG0183	Belongs to the thiolase family
J4N38_RS19575	COG1960	acyl-CoA dehydrogenase activity
J4N38_RS19580	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
J4N38_RS19585	COG1024	Enoyl-CoA hydratase
J4N38_RS19615	COG2259	Doxx family
J4N38_RS19620	COG1741	Belongs to the pirin family
J4N38_RS19630	COG1115	amino acid carrier protein
J4N38_RS19635	COG0583	DNA-binding transcription factor activity
J4N38_RS19640	COG2910	NAD(P)H-binding
J4N38_RS19675	COG1132	(ABC) transporter
J4N38_RS19680	COG1129	ABC transporter
J4N38_RS19705	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
J4N38_RS19710	COG3300	MHYT domain
J4N38_RS19710	COG5001	Diguanylate cyclase
J4N38_RS19715	COG0789	Transcriptional regulator
J4N38_RS19725	COG2176	DNA-directed DNA polymerase activity
J4N38_RS19735	COG4533	DNA binding
J4N38_RS19745	COG2050	protein possibly involved in aromatic compounds catabolism
J4N38_RS19785	COG0737	Belongs to the 5'-nucleotidase family
J4N38_RS19790	COG3593	DNA synthesis involved in DNA repair
J4N38_RS19800	COG0583	DNA-binding transcription factor activity
J4N38_RS19805	COG2116	formate transmembrane transporter activity
J4N38_RS19810	COG2353	YceI-like domain
J4N38_RS19815	COG3038	cytochrome b561
J4N38_RS19835	COG3069	C4-dicarboxylate transmembrane transporter activity
J4N38_RS19840	COG2197	response regulator
J4N38_RS19845	COG3850	Histidine kinase
J4N38_RS19850	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
J4N38_RS19860	COG0243	molybdopterin cofactor binding
J4N38_RS19880	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
J4N38_RS19885	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
J4N38_RS19895	COG1984	allophanate hydrolase subunit 2
J4N38_RS19905	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
J4N38_RS19910	COG4181	ATPase activity
J4N38_RS19920	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
J4N38_RS19925	COG1716	ATPase activity
J4N38_RS19925	COG5001	Diguanylate cyclase
J4N38_RS19935	COG0484	heat shock protein binding
J4N38_RS19950	COG1324	tolerance protein
J4N38_RS19955	COG0210	DNA helicase
J4N38_RS19960	COG1289	transmembrane transporter activity
J4N38_RS19980	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
J4N38_RS20005	COG2827	Endonuclease containing a URI domain
J4N38_RS20010	COG3132	Protein of unknown function, DUF480
J4N38_RS20020	COG2926	Belongs to the UPF0265 family
J4N38_RS20030	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
J4N38_RS20035	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
J4N38_RS20040	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
J4N38_RS20050	COG0247	lactate metabolic process
J4N38_RS20070	COG0545	Peptidyl-prolyl cis-trans isomerase
J4N38_RS20080	COG4067	protein conserved in archaea
J4N38_RS20080	COG0189	ligase activity
J4N38_RS20090	COG0602	queuosine metabolic process
J4N38_RS20095	COG1328	CTP reductase activity
J4N38_RS20130	COG3240	lipase activity
J4N38_RS20135	COG2814	Major facilitator Superfamily
J4N38_RS20140	COG1794	racemase activity, acting on amino acids and derivatives
J4N38_RS20155	COG0183	Belongs to the thiolase family
J4N38_RS20165	COG1309	transcriptional regulator
J4N38_RS20205	COG1522	sequence-specific DNA binding
J4N38_RS20240	COG0515	serine threonine protein kinase
J4N38_RS20240	COG2815	serine threonine protein kinase
J4N38_RS20265	COG3501	Rhs element vgr protein
J4N38_RS20305	COG0739	heme binding
J4N38_RS20315	COG0840	transmembrane signaling receptor activity
J4N38_RS20340	COG2759	Belongs to the formate--tetrahydrofolate ligase family
J4N38_RS20370	COG4172	Belongs to the ABC transporter superfamily
J4N38_RS20375	COG4239	(ABC) transporter, permease
J4N38_RS20380	COG4174	ABC transporter (Permease)
J4N38_RS20385	COG4166	transmembrane transport
J4N38_RS20395	COG0840	transmembrane signaling receptor activity
J4N38_RS20400	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
J4N38_RS20405	COG1067	ATP-dependent peptidase activity
J4N38_RS20415	COG4172	Belongs to the ABC transporter superfamily
J4N38_RS20420	COG0583	DNA-binding transcription factor activity
J4N38_RS20425	COG1620	l-lactate permease
J4N38_RS20430	COG1304	FMN binding
J4N38_RS20445	COG3448	diguanylate cyclase activity
J4N38_RS20445	COG4175	Glycine betaine
J4N38_RS20465	COG1012	belongs to the aldehyde dehydrogenase family
J4N38_RS20470	COG1309	transcriptional regulator
J4N38_RS20480	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
J4N38_RS20485	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
J4N38_RS20500	COG2200	EAL domain
J4N38_RS20505	COG2207	Transcriptional regulator
J4N38_RS20510	COG2814	Major facilitator Superfamily
J4N38_RS20515	COG0583	DNA-binding transcription factor activity
J4N38_RS20520	COG3394	polysaccharide catabolic process
J4N38_RS20525	COG3217	Mosc domain protein beta barrel domain protein
J4N38_RS20525	COG0633	Ferredoxin
J4N38_RS20530	COG2205	protein histidine kinase activity
J4N38_RS20530	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J4N38_RS20540	COG0657	acetylesterase activity
J4N38_RS20550	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
J4N38_RS20550	COG0674	pyruvate-flavodoxin oxidoreductase activity
J4N38_RS20555	COG1013	pyruvate-flavodoxin oxidoreductase activity
J4N38_RS20580	COG2197	response regulator
J4N38_RS20595	COG0516	GMP reductase activity
J4N38_RS20600	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
J4N38_RS20600	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
J4N38_RS20615	COG3437	response regulator, receiver
J4N38_RS20620	COG3850	Histidine kinase
J4N38_RS20620	COG2205	protein histidine kinase activity
J4N38_RS20620	COG3437	response regulator, receiver
J4N38_RS20620	COG4999	Histidine kinase
J4N38_RS20630	COG2172	sigma factor antagonist activity
J4N38_RS20640	COG1366	Belongs to the anti-sigma-factor antagonist family
J4N38_RS20645	COG0840	transmembrane signaling receptor activity
J4N38_RS20665	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
J4N38_RS20670	COG0513	Belongs to the DEAD box helicase family
J4N38_RS20680	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J4N38_RS20680	COG4191	Histidine kinase
J4N38_RS20685	COG0784	Response regulator, receiver
J4N38_RS20685	COG3437	response regulator, receiver
J4N38_RS20690	COG1609	Transcriptional regulator
J4N38_RS20695	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J4N38_RS20705	COG1172	Belongs to the binding-protein-dependent transport system permease family
J4N38_RS20710	COG1129	ABC transporter
J4N38_RS20715	COG1869	D-ribose catabolic process
J4N38_RS20735	COG0004	ammonium transporteR
J4N38_RS20760	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J4N38_RS20810	COG1609	Transcriptional regulator
J4N38_RS20815	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
J4N38_RS20820	COG3265	gluconokinase activity
J4N38_RS20825	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
J4N38_RS20825	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
J4N38_RS20835	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
J4N38_RS20865	COG5001	Diguanylate cyclase
J4N38_RS20875	COG3123	guanosine phosphorylase activity
J4N38_RS20885	COG0668	transmembrane transport
J4N38_RS20905	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
J4N38_RS20945	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J4N38_RS20950	COG4232	protein-disulfide reductase activity
J4N38_RS20965	COG1280	lysine exporter protein (LysE YggA)
J4N38_RS20995	COG0443	Heat shock 70 kDa protein
J4N38_RS21000	COG0583	DNA-binding transcription factor activity
J4N38_RS21010	COG4948	Mandelate Racemase Muconate Lactonizing
J4N38_RS21015	COG1396	sequence-specific DNA binding
J4N38_RS21020	COG5001	Diguanylate cyclase
J4N38_RS21025	COG0683	leucine binding
J4N38_RS21030	COG3706	GGDEF domain
J4N38_RS21045	COG1523	belongs to the glycosyl hydrolase 13 family
J4N38_RS21065	COG3279	Response regulator of the LytR AlgR family
J4N38_RS21070	COG3275	phosphorelay sensor kinase activity
J4N38_RS21085	COG4591	ABC-type transport system involved in lipoprotein release permease component
J4N38_RS21090	COG1136	(ABC) transporter
J4N38_RS21125	COG2249	NAD(P)H dehydrogenase (quinone) activity
J4N38_RS21135	COG0583	DNA-binding transcription factor activity
J4N38_RS21145	COG3530	Putative quorum-sensing-regulated virulence factor
J4N38_RS21160	COG1686	Belongs to the peptidase S11 family
J4N38_RS21175	COG3036	rescue of stalled ribosome
J4N38_RS21180	COG1278	Cold shock
J4N38_RS21195	COG1017	nitric oxide dioxygenase activity
J4N38_RS21195	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
J4N38_RS21200	COG3604	Transcriptional regulator
J4N38_RS21215	COG2249	NAD(P)H dehydrogenase (quinone) activity
J4N38_RS21225	COG0534	Mate efflux family protein
J4N38_RS21230	COG0697	spore germination
J4N38_RS21250	COG0583	DNA-binding transcription factor activity
J4N38_RS21255	COG5001	Diguanylate cyclase
J4N38_RS21290	COG0404	The glycine cleavage system catalyzes the degradation of glycine
J4N38_RS21300	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
J4N38_RS21305	COG0509	glycine decarboxylation via glycine cleavage system
J4N38_RS21340	COG1132	(ABC) transporter
J4N38_RS21345	COG0589	response to stress
J4N38_RS21355	COG2111	Na H antiporter
J4N38_RS21355	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
J4N38_RS21360	COG1006	Multisubunit Na H antiporter MnhC subunit
J4N38_RS21365	COG0651	ATP synthesis coupled electron transport
J4N38_RS21370	COG1863	multisubunit Na H antiporter MnhE subunit
J4N38_RS21375	COG2212	antiporter activity
J4N38_RS21380	COG1320	monovalent cation:proton antiporter activity
J4N38_RS21405	COG0673	inositol 2-dehydrogenase activity
J4N38_RS21420	COG5553	Cysteine dioxygenase type I
J4N38_RS21425	COG0840	transmembrane signaling receptor activity
J4N38_RS21430	COG0840	transmembrane signaling receptor activity
J4N38_RS21470	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
J4N38_RS21480	COG0438	transferase activity, transferring glycosyl groups
J4N38_RS21490	COG1045	serine acetyltransferase
J4N38_RS21505	COG0438	transferase activity, transferring glycosyl groups
J4N38_RS21510	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
J4N38_RS21515	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
J4N38_RS21520	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
J4N38_RS21525	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
J4N38_RS21545	COG4989	oxidoreductase activity
J4N38_RS21555	COG0366	Alpha amylase catalytic
J4N38_RS21565	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
J4N38_RS21570	COG1126	abc transporter atp-binding protein
J4N38_RS21575	COG0765	amino acid transport
J4N38_RS21580	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J4N38_RS21585	COG0765	amino acid transport
J4N38_RS21590	COG0109	protoheme IX farnesyltransferase activity
J4N38_RS21595	COG1612	heme a metabolic process
J4N38_RS21620	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
J4N38_RS21625	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
J4N38_RS21630	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
J4N38_RS21635	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
J4N38_RS21650	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
J4N38_RS21655	COG0574	Belongs to the PEP-utilizing enzyme family
J4N38_RS21655	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
J4N38_RS21660	COG3314	Sporulation integral membrane protein YlbJ
J4N38_RS21670	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
J4N38_RS21695	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J4N38_RS21710	COG1741	Belongs to the pirin family
J4N38_RS21755	COG2205	protein histidine kinase activity
J4N38_RS21760	COG0745	RESPONSE REGULATOR receiver
J4N38_RS21785	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
J4N38_RS21795	COG0523	cobalamin synthesis protein
J4N38_RS21800	COG2988	succinylglutamate desuccinylase activity
J4N38_RS21810	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J4N38_RS21815	COG2423	ornithine cyclodeaminase activity
J4N38_RS21825	COG3938	Belongs to the proline racemase family
J4N38_RS21835	COG2186	Transcriptional regulator
J4N38_RS21850	COG0601	transmembrane transport
J4N38_RS21855	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J4N38_RS21870	COG0006	proline dipeptidase activity
J4N38_RS21890	COG4934	collagen metabolic process
J4N38_RS21900	COG3568	Endonuclease Exonuclease Phosphatase
J4N38_RS21910	COG3291	Pkd domain containing protein
J4N38_RS21915	COG0513	Belongs to the DEAD box helicase family
J4N38_RS21925	COG1388	LysM domain
J4N38_RS21925	COG1376	ErfK ybiS ycfS ynhG family protein
J4N38_RS21930	COG0415	Belongs to the DNA photolyase family
J4N38_RS21935	COG0789	Transcriptional regulator
J4N38_RS21940	COG3272	Protein of unknown function (DUF1722)
J4N38_RS21945	COG0813	purine-nucleoside phosphorylase activity
J4N38_RS21975	COG1566	PFAM secretion protein HlyD family protein
J4N38_RS21980	COG0786	glutamate:sodium symporter activity
J4N38_RS21995	COG1132	(ABC) transporter
J4N38_RS22045	COG1262	PFAM Formylglycine-generating sulfatase enzyme
J4N38_RS22055	COG0259	pyridoxamine-phosphate oxidase activity
J4N38_RS22085	COG3033	Beta-eliminating lyase
J4N38_RS22090	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
J4N38_RS22095	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
J4N38_RS22100	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J4N38_RS22110	COG1999	signal sequence binding
J4N38_RS22125	COG1671	Belongs to the UPF0178 family
J4N38_RS22130	COG0393	Putative heavy-metal-binding
J4N38_RS22135	COG0583	DNA-binding transcription factor activity
J4N38_RS22140	COG2814	Major facilitator Superfamily
J4N38_RS22150	COG0584	glycerophosphoryl diester phosphodiesterase
J4N38_RS22155	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
J4N38_RS22165	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
J4N38_RS22190	COG3527	Alpha-acetolactate decarboxylase
J4N38_RS22195	COG2814	Major facilitator Superfamily
J4N38_RS22200	COG0028	Belongs to the TPP enzyme family
J4N38_RS22360	COG1301	dicarboxylic acid transport
J4N38_RS22365	COG0840	transmembrane signaling receptor activity
J4N38_RS22380	COG4266	Belongs to the allantoicase family
J4N38_RS22400	COG2252	PERMEase
J4N38_RS22415	COG3214	Protein conserved in bacteria
J4N38_RS22430	COG2205	protein histidine kinase activity
J4N38_RS22480	COG0109	protoheme IX farnesyltransferase activity
J4N38_RS22485	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
J4N38_RS22490	COG1845	cytochrome c oxidase, subunit III
J4N38_RS22495	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
J4N38_RS22500	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
J4N38_RS22505	COG2706	6-phosphogluconolactonase activity
J4N38_RS22525	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J4N38_RS22540	COG0459	protein refolding
J4N38_RS22545	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
J4N38_RS22550	COG0071	Belongs to the small heat shock protein (HSP20) family
J4N38_RS22555	COG0628	permease
J4N38_RS22590	COG0668	transmembrane transport
J4N38_RS22595	COG1803	Methylglyoxal synthase
J4N38_RS22595	COG1597	lipid kinase activity
J4N38_RS22625	COG5001	Diguanylate cyclase
J4N38_RS22625	COG5002	protein histidine kinase activity
J4N38_RS22645	COG2084	Dehydrogenase
J4N38_RS22650	COG3622	Belongs to the hyi family
J4N38_RS22655	COG3960	tartronate-semialdehyde synthase activity
J4N38_RS22660	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
J4N38_RS22670	COG0583	DNA-binding transcription factor activity
J4N38_RS22675	COG1288	antiporter activity
J4N38_RS22685	COG1846	Transcriptional regulator
J4N38_RS22690	COG0697	spore germination
J4N38_RS22695	COG1028	Short-chain dehydrogenase reductase Sdr