locus-tag	class	description
J4N44_RS00010	COG0592	DNA-directed DNA polymerase activity
J4N44_RS00020	COG0187	DNA topoisomerase II activity
J4N44_RS00025	COG0071	Belongs to the small heat shock protein (HSP20) family
J4N44_RS00030	COG3977	Valine--pyruvate aminotransferase
J4N44_RS00035	COG0366	Alpha amylase catalytic
J4N44_RS00050	COG2119	membrane
J4N44_RS00060	COG0425	Belongs to the sulfur carrier protein TusA family
J4N44_RS00075	COG0604	alcohol dehydrogenase
J4N44_RS00080	COG0183	Belongs to the thiolase family
J4N44_RS00090	COG1739	Uncharacterized protein family UPF0029
J4N44_RS00095	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
J4N44_RS00145	COG0583	DNA-binding transcription factor activity
J4N44_RS00150	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
J4N44_RS00155	COG2960	long-chain fatty acid transporting porin activity
J4N44_RS00160	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J4N44_RS00165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J4N44_RS00170	COG1309	transcriptional regulator
J4N44_RS00210	COG0546	phosphoglycolate phosphatase activity
J4N44_RS00215	COG4172	Belongs to the ABC transporter superfamily
J4N44_RS00220	COG0747	negative chemotaxis
J4N44_RS00225	COG0601	transmembrane transport
J4N44_RS00230	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J4N44_RS00265	COG1609	Transcriptional regulator
J4N44_RS00270	COG0583	DNA-binding transcription factor activity
J4N44_RS00275	COG2076	Multidrug Resistance protein
J4N44_RS00285	COG0129	dihydroxy-acid dehydratase activity
J4N44_RS00290	COG3265	gluconokinase activity
J4N44_RS00295	COG2610	gluconate transmembrane transporter activity
J4N44_RS00300	COG0800	Aldolase
J4N44_RS00305	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J4N44_RS00315	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
J4N44_RS00325	COG1522	sequence-specific DNA binding
J4N44_RS00330	COG5002	protein histidine kinase activity
J4N44_RS00330	COG5001	Diguanylate cyclase
J4N44_RS00350	COG0589	response to stress
J4N44_RS00355	COG1528	Iron-storage protein
J4N44_RS00365	COG2081	HI0933 family
J4N44_RS00390	COG1322	Protein conserved in bacteria
J4N44_RS00400	COG3165	ubiquinone biosynthetic process from chorismate
J4N44_RS00415	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
J4N44_RS00420	COG0805	protein transport
J4N44_RS00425	COG0084	hydrolase, TatD family'
J4N44_RS00440	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J4N44_RS00440	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J4N44_RS00445	COG0218	Necessary for normal cell division and for the maintenance of normal septation
J4N44_RS00475	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
J4N44_RS00485	COG2204	response regulator
J4N44_RS00490	COG3852	Histidine kinase
J4N44_RS00500	COG0174	glutamine synthetase
J4N44_RS00505	COG1217	gtp-binding protein TYPA
J4N44_RS00525	COG1490	D-aminoacyl-tRNA deacylase activity
J4N44_RS00530	COG0456	acetyltransferase
J4N44_RS00550	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
J4N44_RS00555	COG3031	protein transport across the cell outer membrane
J4N44_RS00565	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
J4N44_RS00570	COG1459	type II secretion system
J4N44_RS00575	COG2165	general secretion pathway protein
J4N44_RS00580	COG2165	general secretion pathway protein
J4N44_RS00585	COG2165	general secretion pathway protein
J4N44_RS00590	COG4795	General secretion pathway protein
J4N44_RS00595	COG3156	type II secretion system protein K
J4N44_RS00600	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
J4N44_RS00605	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
J4N44_RS00615	COG1218	3'(2'),5'-bisphosphate nucleotidase
J4N44_RS00620	COG0494	nUDIX hydrolase
J4N44_RS00630	COG1040	competence protein
J4N44_RS00645	COG2183	response to ionizing radiation
J4N44_RS00655	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
J4N44_RS00670	COG2233	PERMEase
J4N44_RS00680	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
J4N44_RS00685	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J4N44_RS00690	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
J4N44_RS00695	COG1758	RNA polymerase activity
J4N44_RS00700	COG0194	GDP metabolic process
J4N44_RS00715	COG0848	biopolymer transport protein
J4N44_RS00720	COG0811	peptide transport
J4N44_RS00740	COG4174	ABC transporter (Permease)
J4N44_RS00745	COG4239	(ABC) transporter, permease
J4N44_RS00750	COG0747	negative chemotaxis
J4N44_RS00755	COG0444	Belongs to the ABC transporter superfamily
J4N44_RS00760	COG4608	Belongs to the ABC transporter superfamily
J4N44_RS00785	COG0745	RESPONSE REGULATOR receiver
J4N44_RS00790	COG1561	YicC-like family, N-terminal region
J4N44_RS00795	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
J4N44_RS00800	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
J4N44_RS00805	COG1560	Kdo2-lipid A biosynthetic process
J4N44_RS00815	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
J4N44_RS00840	COG2194	sulfuric ester hydrolase activity
J4N44_RS00855	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
J4N44_RS00870	COG0463	Glycosyl transferase, family 2
J4N44_RS00875	COG0859	PFAM glycosyl transferase family 9
J4N44_RS00880	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
J4N44_RS00885	COG3642	lipopolysaccharide core region biosynthetic process
J4N44_RS00905	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
J4N44_RS00915	COG1028	Short-chain dehydrogenase reductase Sdr
J4N44_RS00930	COG1021	2,3-dihydroxybenzoate-AMP ligase
J4N44_RS00935	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
J4N44_RS00950	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
J4N44_RS00955	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
J4N44_RS00960	COG2089	acid synthase
J4N44_RS00970	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
J4N44_RS00985	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
J4N44_RS00995	COG1028	Short-chain dehydrogenase reductase Sdr
J4N44_RS01010	COG1519	Transferase
J4N44_RS01015	COG0859	PFAM glycosyl transferase family 9
J4N44_RS01020	COG1560	Kdo2-lipid A biosynthetic process
J4N44_RS01030	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J4N44_RS01090	COG1216	Glycosyl transferase, family 2
J4N44_RS01100	COG0438	transferase activity, transferring glycosyl groups
J4N44_RS01100	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
J4N44_RS01105	COG0438	transferase activity, transferring glycosyl groups
J4N44_RS01110	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
J4N44_RS01115	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J4N44_RS01135	COG1482	cell wall glycoprotein biosynthetic process
J4N44_RS01150	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
J4N44_RS01165	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
J4N44_RS01170	COG0149	triose-phosphate isomerase activity
J4N44_RS01200	COG1494	fructose-1,6-bisphosphatase
J4N44_RS01210	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
J4N44_RS01215	COG1575	Belongs to the MenA family. Type 1 subfamily
J4N44_RS01235	COG1609	Transcriptional regulator
J4N44_RS01240	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
J4N44_RS01245	COG0254	rRNA binding
J4N44_RS01260	COG0088	Forms part of the polypeptide exit tunnel
J4N44_RS01280	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
J4N44_RS01330	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
J4N44_RS01345	COG1841	ribosomal large subunit assembly
J4N44_RS01350	COG0200	Binds to the 23S rRNA
J4N44_RS01355	COG0201	protein transport
J4N44_RS01360	COG0257	Belongs to the bacterial ribosomal protein bL36 family
J4N44_RS01365	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
J4N44_RS01370	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
J4N44_RS01380	COG0202	RNA polymerase activity
J4N44_RS01385	COG0203	ribosomal protein L17
J4N44_RS01395	COG0545	Peptidyl-prolyl cis-trans isomerase
J4N44_RS01410	COG2153	protein acetylation
J4N44_RS01415	COG0513	Belongs to the DEAD box helicase family
J4N44_RS01425	COG0737	Belongs to the 5'-nucleotidase family
J4N44_RS01430	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
J4N44_RS01430	COG1648	precorrin-2 dehydrogenase activity
J4N44_RS01445	COG3273	potassium ion transport
J4N44_RS01445	COG0471	metal ion transport
J4N44_RS01450	COG0529	Catalyzes the synthesis of activated sulfate
J4N44_RS01470	COG1136	(ABC) transporter
J4N44_RS01485	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
J4N44_RS01495	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J4N44_RS01500	COG0729	surface antigen
J4N44_RS01510	COG2105	PFAM AIG2 family protein
J4N44_RS01520	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
J4N44_RS01530	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
J4N44_RS01535	COG0163	prenyltransferase activity
J4N44_RS01540	COG4143	(ABC) transporter
J4N44_RS01545	COG1178	ABC-type Fe3 transport system permease component
J4N44_RS01550	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
J4N44_RS01585	COG0142	geranyltranstransferase activity
J4N44_RS01590	COG0261	This protein binds to 23S rRNA in the presence of protein L20
J4N44_RS01600	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
J4N44_RS01605	COG2966	Psort location CytoplasmicMembrane, score
J4N44_RS01610	COG3610	response to peptide
J4N44_RS01630	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
J4N44_RS01635	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
J4N44_RS01640	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J4N44_RS01645	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
J4N44_RS01650	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
J4N44_RS01670	COG0473	3-isopropylmalate dehydrogenase activity
J4N44_RS01675	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
J4N44_RS01685	COG0671	phosphoesterase, PA-phosphatase related
J4N44_RS01695	COG0583	DNA-binding transcription factor activity
J4N44_RS01700	COG1022	Amp-dependent synthetase and ligase
J4N44_RS01705	COG0028	Belongs to the TPP enzyme family
J4N44_RS01710	COG0440	acetolactate synthase activity
J4N44_RS01715	COG3706	GGDEF domain
J4N44_RS01725	COG0469	pyruvate kinase activity
J4N44_RS01730	COG1349	DNA-binding transcription factor activity
J4N44_RS01735	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
J4N44_RS01755	COG5002	protein histidine kinase activity
J4N44_RS01760	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J4N44_RS01765	COG3722	fumarate hydratase activity
J4N44_RS01775	COG2213	PTS system mannitol-specific
J4N44_RS01775	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4N44_RS01885	COG0358	DNA primase activity
J4N44_RS01890	COG1610	YqeY-like protein
J4N44_RS01895	COG0828	Belongs to the bacterial ribosomal protein bS21 family
J4N44_RS01900	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
J4N44_RS01905	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
J4N44_RS01915	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
J4N44_RS01920	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
J4N44_RS01935	COG3267	Type II secretory pathway component ExeA
J4N44_RS01935	COG3409	Peptidoglycan-binding domain 1 protein
J4N44_RS01945	COG4991	sh3 domain protein
J4N44_RS01950	COG0306	phosphate transporter
J4N44_RS01955	COG1392	Phosphate transport regulator
J4N44_RS01960	COG3025	triphosphatase activity
J4N44_RS01965	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
J4N44_RS01975	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
J4N44_RS01985	COG1538	Outer membrane efflux protein
J4N44_RS01990	COG0494	nUDIX hydrolase
J4N44_RS01995	COG3151	Protein conserved in bacteria
J4N44_RS02005	COG3150	esterase
J4N44_RS02015	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
J4N44_RS02020	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J4N44_RS02030	COG3105	Protein conserved in bacteria
J4N44_RS02035	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
J4N44_RS02050	COG0723	plastoquinol--plastocyanin reductase activity
J4N44_RS02055	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
J4N44_RS02060	COG2857	Cytochrome c1
J4N44_RS02065	COG0625	glutathione transferase activity
J4N44_RS02070	COG2969	positive regulation of protein catabolic process
J4N44_RS02075	COG2823	Periplasmic or secreted lipoprotein
J4N44_RS02080	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
J4N44_RS02095	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
J4N44_RS02110	COG3116	cell division
J4N44_RS02115	COG0768	penicillin binding
J4N44_RS02120	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
J4N44_RS02125	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
J4N44_RS02140	COG0772	Belongs to the SEDS family
J4N44_RS02155	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
J4N44_RS02160	COG0849	cell division
J4N44_RS02165	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
J4N44_RS02180	COG0494	nUDIX hydrolase
J4N44_RS02190	COG0505	Belongs to the CarA family
J4N44_RS02195	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
J4N44_RS02210	COG0730	response to heat
J4N44_RS02215	COG0583	DNA-binding transcription factor activity
J4N44_RS02220	COG2860	membrane
J4N44_RS02245	COG0493	'glutamate synthase
J4N44_RS02250	COG0067	glutamate synthase
J4N44_RS02250	COG0069	glutamate synthase activity
J4N44_RS02250	COG0070	glutamate synthase
J4N44_RS02260	COG0067	glutamate synthase
J4N44_RS02260	COG0069	glutamate synthase activity
J4N44_RS02260	COG0070	glutamate synthase
J4N44_RS02265	COG1242	4 iron, 4 sulfur cluster binding
J4N44_RS02270	COG4251	negative regulation of phosphorylation
J4N44_RS02270	COG3706	GGDEF domain
J4N44_RS02270	COG2203	Gaf domain
J4N44_RS02270	COG5001	Diguanylate cyclase
J4N44_RS02280	COG0784	Response regulator, receiver
J4N44_RS02280	COG2198	Histidine kinase
J4N44_RS02280	COG5002	protein histidine kinase activity
J4N44_RS02290	COG0745	RESPONSE REGULATOR receiver
J4N44_RS02300	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
J4N44_RS02315	COG0083	homoserine kinase activity
J4N44_RS02320	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
J4N44_RS02325	COG0431	NADPH-dependent FMN reductase
J4N44_RS02355	COG1115	amino acid carrier protein
J4N44_RS02360	COG3022	response to hydroperoxide
J4N44_RS02370	COG0513	Belongs to the DEAD box helicase family
J4N44_RS02385	COG0716	FMN binding
J4N44_RS02390	COG4974	Belongs to the 'phage' integrase family
J4N44_RS02395	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
J4N44_RS02400	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
J4N44_RS02425	COG0667	Aldo Keto reductase
J4N44_RS02445	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
J4N44_RS02450	COG0730	response to heat
J4N44_RS02465	COG1283	sodium-dependent phosphate transmembrane transporter activity
J4N44_RS02470	COG0583	DNA-binding transcription factor activity
J4N44_RS02475	COG0640	Transcriptional regulator
J4N44_RS02480	COG0268	Binds directly to 16S ribosomal RNA
J4N44_RS02485	COG0728	peptidoglycan biosynthetic process
J4N44_RS02490	COG0196	riboflavin kinase activity
J4N44_RS02505	COG1047	Peptidyl-prolyl cis-trans
J4N44_RS02510	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
J4N44_RS02515	COG3279	Response regulator of the LytR AlgR family
J4N44_RS02520	COG3275	phosphorelay sensor kinase activity
J4N44_RS02525	COG1966	Carbon starvation protein
J4N44_RS02545	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
J4N44_RS02555	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
J4N44_RS02560	COG0287	Prephenate dehydrogenase
J4N44_RS02560	COG1605	Chorismate mutase
J4N44_RS02565	COG0739	heme binding
J4N44_RS02575	COG0488	(ABC) transporter
J4N44_RS02590	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
J4N44_RS02595	COG1605	Chorismate mutase
J4N44_RS02595	COG0077	Prephenate dehydratase
J4N44_RS02600	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
J4N44_RS02605	COG0741	lytic transglycosylase activity
J4N44_RS02610	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J4N44_RS02615	COG0564	pseudouridine synthase activity
J4N44_RS02620	COG1496	oxidoreductase activity
J4N44_RS02625	COG0542	response to heat
J4N44_RS02680	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
J4N44_RS02685	COG0826	peptidase U32
J4N44_RS02695	COG0745	RESPONSE REGULATOR receiver
J4N44_RS02700	COG5002	protein histidine kinase activity
J4N44_RS02710	COG0248	Ppx GppA phosphatase
J4N44_RS02715	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
J4N44_RS02720	COG0573	inorganic phosphate transmembrane transporter activity
J4N44_RS02725	COG0581	inorganic phosphate transmembrane transporter activity
J4N44_RS02730	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
J4N44_RS02735	COG0704	Plays a role in the regulation of phosphate uptake
J4N44_RS02765	COG0450	alkyl hydroperoxide reductase
J4N44_RS02770	COG0583	DNA-binding transcription factor activity
J4N44_RS02775	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
J4N44_RS02785	COG0517	IMP dehydrogenase activity
J4N44_RS02810	COG1862	Preprotein translocase
J4N44_RS02815	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J4N44_RS02820	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J4N44_RS02830	COG0483	inositol monophosphate 1-phosphatase activity
J4N44_RS02835	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
J4N44_RS02850	COG0822	iron-sulfur transferase activity
J4N44_RS02855	COG0316	Belongs to the HesB IscA family
J4N44_RS02870	COG0633	Ferredoxin
J4N44_RS02875	COG2975	iron-sulfur cluster assembly
J4N44_RS02910	COG2976	Protein conserved in bacteria
J4N44_RS02915	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J4N44_RS02930	COG2199	diguanylate cyclase activity
J4N44_RS02930	COG2203	Gaf domain
J4N44_RS02945	COG0516	GMP reductase activity
J4N44_RS02945	COG0517	IMP dehydrogenase activity
J4N44_RS02955	COG1757	Na H antiporter
J4N44_RS02965	COG1584	GPR1 FUN34 yaaH family protein
J4N44_RS02970	COG1115	amino acid carrier protein
J4N44_RS02980	COG0583	DNA-binding transcription factor activity
J4N44_RS02985	COG0668	transmembrane transport
J4N44_RS02990	COG2873	o-acetylhomoserine
J4N44_RS02995	COG0316	Belongs to the HesB IscA family
J4N44_RS03000	COG0719	Fe-S assembly protein
J4N44_RS03005	COG0396	ATPase activity
J4N44_RS03010	COG0719	Fe-S assembly protein
J4N44_RS03030	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
J4N44_RS03050	COG1289	transmembrane transporter activity
J4N44_RS03055	COG0583	DNA-binding transcription factor activity
J4N44_RS03070	COG2867	negative regulation of translational initiation
J4N44_RS03075	COG2914	Belongs to the UPF0125 (RnfH) family
J4N44_RS03080	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J4N44_RS03085	COG0497	DNA recombination
J4N44_RS03105	COG1301	dicarboxylic acid transport
J4N44_RS03125	COG4969	Belongs to the N-Me-Phe pilin family
J4N44_RS03145	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
J4N44_RS03150	COG0590	tRNA wobble adenosine to inosine editing
J4N44_RS03160	COG0047	phosphoribosylformylglycinamidine synthase activity
J4N44_RS03160	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
J4N44_RS03190	COG2195	Cleaves the N-terminal amino acid of tripeptides
J4N44_RS03195	COG2252	PERMEase
J4N44_RS03200	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
J4N44_RS03205	COG1073	alpha beta
J4N44_RS03220	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
J4N44_RS03225	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
J4N44_RS03230	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
J4N44_RS03230	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
J4N44_RS03255	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
J4N44_RS03260	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
J4N44_RS03270	COG0142	geranyltranstransferase activity
J4N44_RS03280	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
J4N44_RS03295	COG0583	DNA-binding transcription factor activity
J4N44_RS03305	COG2363	Small membrane protein
J4N44_RS03325	COG1611	Belongs to the LOG family
J4N44_RS03350	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
J4N44_RS03355	COG0737	Belongs to the 5'-nucleotidase family
J4N44_RS03365	COG1464	Belongs to the NlpA lipoprotein family
J4N44_RS03370	COG2011	ABC-type metal ion transport system permease component
J4N44_RS03375	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
J4N44_RS03380	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
J4N44_RS03390	COG1263	PTS System
J4N44_RS03390	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J4N44_RS03395	COG0366	Alpha amylase catalytic
J4N44_RS03410	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
J4N44_RS03415	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
J4N44_RS03435	COG1686	Belongs to the peptidase S11 family
J4N44_RS03440	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
J4N44_RS03445	COG0772	Belongs to the SEDS family
J4N44_RS03450	COG0768	penicillin binding
J4N44_RS03460	COG0799	negative regulation of ribosome biogenesis
J4N44_RS03465	COG1466	dna polymerase III delta subunit
J4N44_RS03470	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
J4N44_RS03480	COG2888	peptidyl-tyrosine sulfation
J4N44_RS03485	COG0815	Transfers the fatty acyl group on membrane lipoproteins
J4N44_RS03490	COG4535	Mg2 and Co2 transporter CorC
J4N44_RS03500	COG1702	phosphate starvation-inducible protein PhoH
J4N44_RS03510	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J4N44_RS03630	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
J4N44_RS03655	COG2890	protein-(glutamine-N5) methyltransferase activity
J4N44_RS03660	COG3094	Invasion gene expression up-regulator, SirB
J4N44_RS03665	COG2912	Transglutaminase-like superfamily
J4N44_RS03670	COG2877	3-deoxy-8-phosphooctulonate synthase activity
J4N44_RS03675	COG0737	Belongs to the 5'-nucleotidase family
J4N44_RS03680	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
J4N44_RS03685	COG1187	pseudouridine synthase activity
J4N44_RS03690	COG2840	Smr protein MutS2
J4N44_RS03730	COG2217	Heavy metal translocating P-type atpase
J4N44_RS03730	COG2608	mercury ion transmembrane transporter activity
J4N44_RS03740	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
J4N44_RS03795	COG0784	Response regulator, receiver
J4N44_RS03795	COG0835	chemotaxis
J4N44_RS03800	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
J4N44_RS03805	COG1815	bacterial-type flagellum-dependent cell motility
J4N44_RS03810	COG1558	bacterial-type flagellum-dependent cell motility
J4N44_RS03825	COG4787	bacterial-type flagellum-dependent cell motility
J4N44_RS03835	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
J4N44_RS03840	COG1706	bacterial-type flagellum-dependent cell motility
J4N44_RS03845	COG3951	Flagellar rod assembly protein muramidase FlgJ
J4N44_RS03845	COG1705	Flagellar rod assembly protein muramidase FlgJ
J4N44_RS03860	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
J4N44_RS03870	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
J4N44_RS03875	COG2190	(PTS) system
J4N44_RS03880	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
J4N44_RS03885	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4N44_RS03890	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
J4N44_RS03895	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
J4N44_RS03925	COG0330	HflC and HflK could
J4N44_RS03930	COG3118	belongs to the thioredoxin family
J4N44_RS03940	COG0300	oxidoreductase activity
J4N44_RS03945	COG1090	epimerase
J4N44_RS03975	COG0622	Phosphoesterase
J4N44_RS03995	COG3710	Transcriptional regulator
J4N44_RS04010	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
J4N44_RS04015	COG3104	oligopeptide transport
J4N44_RS04025	COG0367	asparagine synthase
J4N44_RS04030	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
J4N44_RS04030	COG4651	solute:proton antiporter activity
J4N44_RS04035	COG1940	carbohydrate kinase activity
J4N44_RS04035	COG1846	Transcriptional regulator
J4N44_RS04040	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
J4N44_RS04045	COG2190	(PTS) system
J4N44_RS04045	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J4N44_RS04045	COG1263	PTS System
J4N44_RS04055	COG2165	general secretion pathway protein
J4N44_RS04060	COG0735	belongs to the Fur family
J4N44_RS04070	COG0716	FMN binding
J4N44_RS04080	COG0596	Alpha beta hydrolase
J4N44_RS04085	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
J4N44_RS04090	COG0033	Phosphoglucomutase
J4N44_RS04100	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
J4N44_RS04115	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
J4N44_RS04120	COG1053	succinate dehydrogenase
J4N44_RS04130	COG0567	Dehydrogenase, E1 component
J4N44_RS04135	COG0508	dehydrogenase complex catalyzes the overall conversion of
J4N44_RS04150	COG1108	ABC-type Mn2 Zn2 transport systems permease components
J4N44_RS04155	COG1121	(ABC) transporter
J4N44_RS04160	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
J4N44_RS04165	COG4977	sequence-specific DNA binding
J4N44_RS04170	COG1918	ferrous iron import across plasma membrane
J4N44_RS04200	COG3102	Protein conserved in bacteria
J4N44_RS04205	COG0788	formyltetrahydrofolate deformylase activity
J4N44_RS04210	COG1199	ATP-dependent helicase activity
J4N44_RS04215	COG1214	PFAM Peptidase M22, glycoprotease
J4N44_RS04225	COG3065	identical protein binding
J4N44_RS04230	COG2267	carboxylic ester hydrolase activity
J4N44_RS04235	COG0318	PFAM AMP-dependent synthetase and ligase
J4N44_RS04240	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
J4N44_RS04245	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
J4N44_RS04250	COG2894	cell division
J4N44_RS04265	COG2951	lytic endotransglycosylase activity
J4N44_RS04275	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
J4N44_RS04310	COG1028	Short-chain dehydrogenase reductase Sdr
J4N44_RS04345	COG2986	histidine ammonia-lyase
J4N44_RS04350	COG1216	Glycosyl transferase, family 2
J4N44_RS04370	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J4N44_RS04375	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J4N44_RS04405	COG2226	methyltransferase
J4N44_RS04420	COG1028	Short-chain dehydrogenase reductase Sdr
J4N44_RS04430	COG1169	isochorismate synthase
J4N44_RS04435	COG1021	2,3-dihydroxybenzoate-AMP ligase
J4N44_RS04440	COG1535	isochorismatase
J4N44_RS04440	COG3433	isochorismatase activity
J4N44_RS04445	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J4N44_RS04445	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J4N44_RS04460	COG4771	TonB-dependent receptor
J4N44_RS04465	COG1253	flavin adenine dinucleotide binding
J4N44_RS04470	COG0513	Belongs to the DEAD box helicase family
J4N44_RS04475	COG0569	domain protein
J4N44_RS04480	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
J4N44_RS04495	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
J4N44_RS04500	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
J4N44_RS04505	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
J4N44_RS04520	COG4191	Histidine kinase
J4N44_RS04540	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
J4N44_RS04545	COG0776	regulation of translation
J4N44_RS04550	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J4N44_RS04575	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
J4N44_RS04580	COG0436	Aminotransferase
J4N44_RS04585	COG1169	isochorismate synthase
J4N44_RS04595	COG0596	Alpha beta hydrolase
J4N44_RS04600	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
J4N44_RS04615	COG1263	PTS System
J4N44_RS04615	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J4N44_RS04615	COG2190	(PTS) system
J4N44_RS04620	COG0583	DNA-binding transcription factor activity
J4N44_RS04630	COG2855	membrane
J4N44_RS04635	COG0477	Major facilitator Superfamily
J4N44_RS04685	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J4N44_RS04710	COG1522	sequence-specific DNA binding
J4N44_RS04720	COG1946	Acyl-CoA thioesterase
J4N44_RS04725	COG3126	Type III secretion system lipoprotein chaperone (YscW)
J4N44_RS04790	COG0732	type I restriction modification DNA specificity domain
J4N44_RS04810	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
J4N44_RS04855	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
J4N44_RS04860	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J4N44_RS04865	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
J4N44_RS04870	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
J4N44_RS04875	COG0517	IMP dehydrogenase activity
J4N44_RS04875	COG0617	tRNA 3'-terminal CCA addition
J4N44_RS04875	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
J4N44_RS04885	COG2217	Heavy metal translocating P-type atpase
J4N44_RS04905	COG0537	adenosine 5'-monophosphoramidase activity
J4N44_RS04935	COG1252	NADH dehydrogenase
J4N44_RS04950	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
J4N44_RS04960	COG4591	ABC-type transport system involved in lipoprotein release permease component
J4N44_RS04965	COG1136	(ABC) transporter
J4N44_RS04970	COG4591	ABC-type transport system involved in lipoprotein release permease component
J4N44_RS04985	COG1132	(ABC) transporter
J4N44_RS05005	COG2719	SpoVR family
J4N44_RS05010	COG2718	Belongs to the UPF0229 family
J4N44_RS05015	COG2766	serine protein kinase
J4N44_RS05030	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
J4N44_RS05040	COG1882	Formate acetyltransferase
J4N44_RS05075	COG0708	Exodeoxyribonuclease III
J4N44_RS05080	COG0840	transmembrane signaling receptor activity
J4N44_RS05095	COG0730	response to heat
J4N44_RS05100	COG1199	ATP-dependent helicase activity
J4N44_RS05110	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
J4N44_RS05115	COG1187	pseudouridine synthase activity
J4N44_RS05125	COG1278	Cold shock
J4N44_RS05135	COG0542	response to heat
J4N44_RS05140	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
J4N44_RS05170	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
J4N44_RS05175	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
J4N44_RS05180	COG0297	glycogen (starch) synthase activity
J4N44_RS05200	COG3070	regulator of competence-specific genes
J4N44_RS05215	COG0745	RESPONSE REGULATOR receiver
J4N44_RS05220	COG1434	Gram-negative-bacterium-type cell wall biogenesis
J4N44_RS05225	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
J4N44_RS05235	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
J4N44_RS05240	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
J4N44_RS05260	COG4067	protein conserved in archaea
J4N44_RS05260	COG0189	ligase activity
J4N44_RS05275	COG1801	Protein of unknown function DUF72
J4N44_RS05290	COG0840	transmembrane signaling receptor activity
J4N44_RS05295	COG0632	four-way junction helicase activity
J4N44_RS05305	COG1271	oxidase subunit
J4N44_RS05310	COG1294	oxidase, subunit
J4N44_RS05315	COG4890	Cyd operon protein YbgT
J4N44_RS05325	COG0824	Thioesterase
J4N44_RS05330	COG0811	peptide transport
J4N44_RS05345	COG0823	Involved in the tonB-independent uptake of proteins
J4N44_RS05350	COG2885	chlorophyll binding
J4N44_RS05355	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
J4N44_RS05370	COG0673	inositol 2-dehydrogenase activity
J4N44_RS05375	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
J4N44_RS05375	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4N44_RS05375	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4N44_RS05380	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4N44_RS05385	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4N44_RS05390	COG1882	Formate acetyltransferase
J4N44_RS05395	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
J4N44_RS05400	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J4N44_RS05405	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
J4N44_RS05410	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4N44_RS05415	COG2207	Transcriptional regulator
J4N44_RS05420	COG0371	Dehydrogenase
J4N44_RS05425	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J4N44_RS05445	COG3766	membrane
J4N44_RS05455	COG0754	glutathionylspermidine amidase activity
J4N44_RS05465	COG5002	protein histidine kinase activity
J4N44_RS05465	COG0784	Response regulator, receiver
J4N44_RS05545	COG4669	(LipO)protein
J4N44_RS05590	COG4792	protein secretion
J4N44_RS05595	COG4791	protein targeting
J4N44_RS05600	COG4794	Type iii secretion
J4N44_RS05605	COG4790	Type iii secretion
J4N44_RS05675	COG0457	Tetratricopeptide repeat
J4N44_RS05695	COG0789	Transcriptional regulator
J4N44_RS05700	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
J4N44_RS05715	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J4N44_RS05715	COG1263	PTS System
J4N44_RS05720	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J4N44_RS05725	COG1621	beta-fructofuranosidase activity
J4N44_RS05730	COG2824	Alkylphosphonate utilization operon protein PhnA
J4N44_RS05745	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J4N44_RS05770	COG0534	Mate efflux family protein
J4N44_RS05775	COG0444	Belongs to the ABC transporter superfamily
J4N44_RS05780	COG4608	Belongs to the ABC transporter superfamily
J4N44_RS05785	COG0747	negative chemotaxis
J4N44_RS05800	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
J4N44_RS05815	COG2076	Multidrug Resistance protein
J4N44_RS05850	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J4N44_RS05855	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J4N44_RS05865	COG2186	Transcriptional regulator
J4N44_RS05875	COG1288	antiporter activity
J4N44_RS05905	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J4N44_RS05925	COG2176	DNA-directed DNA polymerase activity
J4N44_RS05930	COG0517	IMP dehydrogenase activity
J4N44_RS05935	COG2186	Transcriptional regulator
J4N44_RS05940	COG1028	Short-chain dehydrogenase reductase Sdr
J4N44_RS05945	COG2186	Transcriptional regulator
J4N44_RS05965	COG1917	Cupin 2, conserved barrel domain protein
J4N44_RS05970	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J4N44_RS05975	COG0800	Aldolase
J4N44_RS05980	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J4N44_RS05990	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
J4N44_RS06015	COG3568	Endonuclease Exonuclease Phosphatase
J4N44_RS06025	COG4934	collagen metabolic process
J4N44_RS06060	COG0686	Belongs to the AlaDH PNT family
J4N44_RS06070	COG1674	ftsk spoiiie
J4N44_RS06080	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
J4N44_RS06100	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
J4N44_RS06145	COG0300	oxidoreductase activity
J4N44_RS06160	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
J4N44_RS06170	COG2268	Band 7 protein
J4N44_RS06180	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
J4N44_RS06190	COG0482	sulfurtransferase activity
J4N44_RS06200	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J4N44_RS06210	COG1757	Na H antiporter
J4N44_RS06225	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
J4N44_RS06230	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
J4N44_RS06235	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
J4N44_RS06235	COG0131	Imidazoleglycerol-phosphate dehydratase
J4N44_RS06240	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
J4N44_RS06245	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
J4N44_RS06255	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
J4N44_RS06255	COG0140	phosphoribosyl-ATP diphosphatase activity
J4N44_RS06260	COG3012	SEC-C Motif Domain Protein
J4N44_RS06265	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
J4N44_RS06270	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J4N44_RS06275	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
J4N44_RS06280	COG0215	cysteine-tRNA ligase activity
J4N44_RS06285	COG1435	thymidine kinase activity
J4N44_RS06290	COG1434	Gram-negative-bacterium-type cell wall biogenesis
J4N44_RS06315	COG2116	formate transmembrane transporter activity
J4N44_RS06325	COG0390	transport system, permease component
J4N44_RS06330	COG4459	periplasmic nitrate reductase
J4N44_RS06335	COG3005	denitrification pathway
J4N44_RS06340	COG0243	molybdopterin cofactor binding
J4N44_RS06355	COG1121	(ABC) transporter
J4N44_RS06360	COG1108	ABC-type Mn2 Zn2 transport systems permease components
J4N44_RS06365	COG1108	ABC-type Mn2 Zn2 transport systems permease components
J4N44_RS06370	COG1227	inorganic diphosphatase activity
J4N44_RS06380	COG4172	Belongs to the ABC transporter superfamily
J4N44_RS06390	COG4171	peptide transport system, permease
J4N44_RS06405	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
J4N44_RS06410	COG1842	Phage shock protein A
J4N44_RS06430	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J4N44_RS06440	COG2818	Glycosylase
J4N44_RS06445	COG5380	lipid catabolic process
J4N44_RS06450	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
J4N44_RS06455	COG0626	cystathionine gamma-synthase activity
J4N44_RS06465	COG0733	neurotransmitter:sodium symporter activity
J4N44_RS06475	COG0564	pseudouridine synthase activity
J4N44_RS06485	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
J4N44_RS06490	COG1151	hydroxylamine reductase activity
J4N44_RS06495	COG3604	Transcriptional regulator
J4N44_RS06505	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
J4N44_RS06510	COG4136	ATPase activity
J4N44_RS06515	COG4135	transport system, permease component
J4N44_RS06520	COG4134	Bacterial extracellular solute-binding protein
J4N44_RS06525	COG0398	Pfam SNARE associated Golgi protein
J4N44_RS06535	COG0493	'glutamate synthase
J4N44_RS06560	COG0659	secondary active sulfate transmembrane transporter activity
J4N44_RS06570	COG3313	Fe-S protein
J4N44_RS06625	COG1061	Type III restriction enzyme res subunit
J4N44_RS06630	COG1187	pseudouridine synthase activity
J4N44_RS06635	COG2814	Major facilitator Superfamily
J4N44_RS06645	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J4N44_RS06655	COG1609	Transcriptional regulator
J4N44_RS06660	COG0702	epimerase
J4N44_RS06665	COG0534	Mate efflux family protein
J4N44_RS06670	COG4181	ATPase activity
J4N44_RS06700	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
J4N44_RS06710	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
J4N44_RS06720	COG1737	Transcriptional regulator
J4N44_RS06725	COG0076	glutamate decarboxylase activity
J4N44_RS06735	COG2431	L-lysine efflux transmembrane transporter activity
J4N44_RS06745	COG3070	regulator of competence-specific genes
J4N44_RS06760	COG4191	Histidine kinase
J4N44_RS06760	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J4N44_RS06770	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
J4N44_RS06780	COG3447	MASE1 domain protein
J4N44_RS06780	COG5001	Diguanylate cyclase
J4N44_RS06780	COG5002	protein histidine kinase activity
J4N44_RS06800	COG0583	DNA-binding transcription factor activity
J4N44_RS06805	COG2610	gluconate transmembrane transporter activity
J4N44_RS06815	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
J4N44_RS06820	COG4988	ABC transporter
J4N44_RS06825	COG0492	ferredoxin-NADP+ reductase activity
J4N44_RS06845	COG3706	GGDEF domain
J4N44_RS06850	COG0471	metal ion transport
J4N44_RS06855	COG2949	membrane
J4N44_RS06865	COG1643	Atp-dependent helicase
J4N44_RS06905	COG0471	metal ion transport
J4N44_RS06910	COG4191	Histidine kinase
J4N44_RS06910	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J4N44_RS06920	COG3300	MHYT domain
J4N44_RS06920	COG5001	Diguanylate cyclase
J4N44_RS06930	COG1280	lysine exporter protein (LysE YggA)
J4N44_RS06935	COG1328	CTP reductase activity
J4N44_RS06940	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
J4N44_RS06950	COG0861	Integral membrane protein TerC family
J4N44_RS06960	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
J4N44_RS06970	COG1454	alcohol dehydrogenase
J4N44_RS06975	COG0814	amino acid
J4N44_RS06990	COG1120	ATPase activity
J4N44_RS06995	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
J4N44_RS07000	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J4N44_RS07005	COG4774	siderophore transport
J4N44_RS07020	COG1132	(ABC) transporter
J4N44_RS07025	COG1132	(ABC) transporter
J4N44_RS07030	COG2165	general secretion pathway protein
J4N44_RS07040	COG0583	DNA-binding transcription factor activity
J4N44_RS07065	COG0443	Heat shock 70 kDa protein
J4N44_RS07070	COG0443	Heat shock 70 kDa protein
J4N44_RS07080	COG3706	GGDEF domain
J4N44_RS07110	COG0243	molybdopterin cofactor binding
J4N44_RS07115	COG0437	4 iron, 4 sulfur cluster binding
J4N44_RS07120	COG3302	dmso reductase anchor subunit
J4N44_RS07135	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
J4N44_RS07140	COG1643	Atp-dependent helicase
J4N44_RS07165	COG3063	Type IV pilus biogenesis stability protein PilW
J4N44_RS07190	COG0531	amino acid
J4N44_RS07195	COG1280	lysine exporter protein (LysE YggA)
J4N44_RS07200	COG0583	DNA-binding transcription factor activity
J4N44_RS07205	COG1560	Kdo2-lipid A biosynthetic process
J4N44_RS07220	COG1846	Transcriptional regulator
J4N44_RS07230	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
J4N44_RS07235	COG2197	response regulator
J4N44_RS07270	COG1280	lysine exporter protein (LysE YggA)
J4N44_RS07285	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J4N44_RS07290	COG2358	TRAP transporter, solute receptor (TAXI family
J4N44_RS07295	COG0730	response to heat
J4N44_RS07320	COG0456	acetyltransferase
J4N44_RS07330	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
J4N44_RS07335	COG2815	serine threonine protein kinase
J4N44_RS07335	COG0515	serine threonine protein kinase
J4N44_RS07440	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
J4N44_RS07445	COG0372	Belongs to the citrate synthase family
J4N44_RS07455	COG2828	Protein conserved in bacteria
J4N44_RS07485	COG0561	phosphatase activity
J4N44_RS07490	COG0602	queuosine metabolic process
J4N44_RS07500	COG2203	Gaf domain
J4N44_RS07500	COG2199	diguanylate cyclase activity
J4N44_RS07530	COG3064	Membrane
J4N44_RS07540	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
J4N44_RS07550	COG0297	glycogen (starch) synthase activity
J4N44_RS07580	COG0438	transferase activity, transferring glycosyl groups
J4N44_RS07590	COG2204	response regulator
J4N44_RS07610	COG2885	chlorophyll binding
J4N44_RS07620	COG1793	dna ligase
J4N44_RS07630	COG0534	Mate efflux family protein
J4N44_RS07635	COG0307	riboflavin synthase, alpha
J4N44_RS07645	COG3001	Fructosamine kinase
J4N44_RS07650	COG2201	protein-glutamate methylesterase activity
J4N44_RS07655	COG3706	GGDEF domain
J4N44_RS07665	COG0791	NLP P60 protein
J4N44_RS07670	COG0840	transmembrane signaling receptor activity
J4N44_RS07710	COG3148	PFAM DTW domain containing protein
J4N44_RS07715	COG1940	carbohydrate kinase activity
J4N44_RS07725	COG0303	'Molybdopterin
J4N44_RS07735	COG3842	ATPase activity
J4N44_RS07740	COG4662	Binding-protein-dependent transport system inner membrane component
J4N44_RS07750	COG2204	response regulator
J4N44_RS07755	COG4191	Histidine kinase
J4N44_RS07770	COG0488	(ABC) transporter
J4N44_RS07775	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
J4N44_RS07795	COG3381	protein complex oligomerization
J4N44_RS07805	COG0243	molybdopterin cofactor binding
J4N44_RS07805	COG3383	formate dehydrogenase (NAD+) activity
J4N44_RS07810	COG0437	4 iron, 4 sulfur cluster binding
J4N44_RS07830	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
J4N44_RS07835	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
J4N44_RS07845	COG1177	transmembrane transport
J4N44_RS07855	COG3842	ATPase activity
J4N44_RS07865	COG2992	FlgJ-related protein
J4N44_RS07880	COG0589	response to stress
J4N44_RS07885	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J4N44_RS07900	COG2217	Heavy metal translocating P-type atpase
J4N44_RS07910	COG2010	Cytochrome c
J4N44_RS07925	COG3278	Belongs to the heme-copper respiratory oxidase family
J4N44_RS07940	COG0784	Response regulator, receiver
J4N44_RS07940	COG2205	protein histidine kinase activity
J4N44_RS08050	COG1067	ATP-dependent peptidase activity
J4N44_RS08055	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
J4N44_RS08070	COG0488	(ABC) transporter
J4N44_RS08095	COG2902	Dehydrogenase
J4N44_RS08105	COG0308	aminopeptidase N
J4N44_RS08120	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
J4N44_RS08125	COG1956	GAF domain-containing protein
J4N44_RS08130	COG1132	(ABC) transporter
J4N44_RS08135	COG2995	paraquat-inducible protein a
J4N44_RS08140	COG3008	intermembrane lipid transfer
J4N44_RS08165	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
J4N44_RS08180	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J4N44_RS08185	COG4597	amino acid ABC transporter
J4N44_RS08190	COG0765	amino acid transport
J4N44_RS08195	COG1126	abc transporter atp-binding protein
J4N44_RS08200	COG0670	Belongs to the BI1 family
J4N44_RS08205	COG2920	part of a sulfur-relay system
J4N44_RS08210	COG1254	Belongs to the acylphosphatase family
J4N44_RS08245	COG5001	Diguanylate cyclase
J4N44_RS08245	COG3300	MHYT domain
J4N44_RS08250	COG4999	Histidine kinase
J4N44_RS08250	COG3850	Histidine kinase
J4N44_RS08250	COG3437	response regulator, receiver
J4N44_RS08250	COG2205	protein histidine kinase activity
J4N44_RS08265	COG0110	maltose O-acetyltransferase activity
J4N44_RS08290	COG1846	Transcriptional regulator
J4N44_RS08300	COG3247	response to pH
J4N44_RS08305	COG0668	transmembrane transport
J4N44_RS08315	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
J4N44_RS08375	COG4964	Belongs to the GSP D family
J4N44_RS08400	COG2207	Transcriptional regulator
J4N44_RS08420	COG0589	response to stress
J4N44_RS08425	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
J4N44_RS08430	COG0363	glucosamine-6-phosphate deaminase activity
J4N44_RS08435	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
J4N44_RS08445	COG4774	siderophore transport
J4N44_RS08450	COG4565	transcriptional regulatory protein
J4N44_RS08455	COG3290	protein histidine kinase activity
J4N44_RS08470	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J4N44_RS08495	COG0583	DNA-binding transcription factor activity
J4N44_RS08500	COG2814	Major facilitator Superfamily
J4N44_RS08510	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
J4N44_RS08515	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
J4N44_RS08555	COG2186	Transcriptional regulator
J4N44_RS08575	COG0702	epimerase
J4N44_RS08580	COG0583	DNA-binding transcription factor activity
J4N44_RS08585	COG1404	Belongs to the peptidase S8 family
J4N44_RS08590	COG1858	cytochrome C peroxidase
J4N44_RS08595	COG0527	aspartate kinase activity
J4N44_RS08600	COG0662	Cupin 2, conserved barrel domain protein
J4N44_RS08605	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
J4N44_RS08610	COG0456	acetyltransferase
J4N44_RS08615	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
J4N44_RS08625	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
J4N44_RS08630	COG0534	Mate efflux family protein
J4N44_RS08645	COG1368	sulfuric ester hydrolase activity
J4N44_RS08685	COG1115	amino acid carrier protein
J4N44_RS08690	COG1012	belongs to the aldehyde dehydrogenase family
J4N44_RS08695	COG3284	Transcriptional regulator
J4N44_RS08730	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
J4N44_RS08740	COG3051	citrate lyase alpha subunit
J4N44_RS08745	COG2301	Belongs to the HpcH HpaI aldolase family
J4N44_RS08755	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
J4N44_RS08765	COG3630	sodium ion export across plasma membrane
J4N44_RS08770	COG5016	pyruvate
J4N44_RS08770	COG0511	ligase activity, forming carbon-carbon bonds
J4N44_RS08775	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
J4N44_RS08785	COG4565	transcriptional regulatory protein
J4N44_RS08825	COG1051	belongs to the nudix hydrolase family
J4N44_RS08870	COG0625	glutathione transferase activity
J4N44_RS08880	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
J4N44_RS08895	COG2195	Cleaves the N-terminal amino acid of tripeptides
J4N44_RS08905	COG0601	transmembrane transport
J4N44_RS08910	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J4N44_RS08915	COG0444	Belongs to the ABC transporter superfamily
J4N44_RS08935	COG3291	Pkd domain containing protein
J4N44_RS08950	COG0642	Histidine kinase
J4N44_RS08955	COG0745	RESPONSE REGULATOR receiver
J4N44_RS08965	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J4N44_RS08970	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J4N44_RS08990	COG0813	purine-nucleoside phosphorylase activity
J4N44_RS08995	COG1177	transmembrane transport
J4N44_RS09000	COG1176	ABC-type spermidine putrescine transport system, permease component I
J4N44_RS09005	COG3842	ATPase activity
J4N44_RS09010	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J4N44_RS09015	COG2423	ornithine cyclodeaminase activity
J4N44_RS09025	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J4N44_RS09030	COG3938	Belongs to the proline racemase family
J4N44_RS09060	COG1451	nucleotide metabolic process
J4N44_RS09085	COG0583	DNA-binding transcription factor activity
J4N44_RS09140	COG4139	cobalamin transport
J4N44_RS09155	COG2062	phosphohistidine phosphatase, SixA
J4N44_RS09165	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
J4N44_RS09175	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
J4N44_RS09180	COG0702	epimerase
J4N44_RS09185	COG1823	symporter activity
J4N44_RS09195	COG2925	Exonuclease
J4N44_RS09205	COG1346	cytolysis
J4N44_RS09270	COG0072	phenylalanine-tRNA ligase activity
J4N44_RS09270	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J4N44_RS09280	COG3706	GGDEF domain
J4N44_RS09325	COG0251	oxidation-reduction process
J4N44_RS09335	COG0291	Belongs to the bacterial ribosomal protein bL35 family
J4N44_RS09360	COG2188	Transcriptional regulator
J4N44_RS09370	COG0010	Belongs to the arginase family
J4N44_RS09380	COG2986	histidine ammonia-lyase
J4N44_RS09395	COG0247	lactate metabolic process
J4N44_RS09395	COG0277	FAD linked oxidase domain protein
J4N44_RS09430	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
J4N44_RS09460	COG0519	Catalyzes the synthesis of GMP from XMP
J4N44_RS09625	COG3340	Belongs to the peptidase S51 family
J4N44_RS09735	COG2026	Addiction module toxin, RelE StbE family
J4N44_RS09765	COG1192	Involved in chromosome partitioning
J4N44_RS10065	COG0791	NLP P60 protein
J4N44_RS10475	COG0791	NLP P60 protein
J4N44_RS10480	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
J4N44_RS10635	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J4N44_RS10650	COG3106	COG3106 Predicted ATPase
J4N44_RS10665	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
J4N44_RS10670	COG2205	protein histidine kinase activity
J4N44_RS10670	COG0784	Response regulator, receiver
J4N44_RS10685	COG0814	amino acid
J4N44_RS10690	COG1760	l-serine dehydratase
J4N44_RS10695	COG5001	Diguanylate cyclase
J4N44_RS10695	COG3300	MHYT domain
J4N44_RS10710	COG2197	response regulator
J4N44_RS10715	COG0720	synthase
J4N44_RS10720	COG0840	transmembrane signaling receptor activity
J4N44_RS10725	COG0017	Asparaginyl-tRNA synthetase
J4N44_RS10740	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J4N44_RS10755	COG2770	Histidine kinase
J4N44_RS10755	COG3437	response regulator, receiver
J4N44_RS10760	COG1448	Aminotransferase
J4N44_RS10780	COG0840	transmembrane signaling receptor activity
J4N44_RS10785	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
J4N44_RS10790	COG1846	Transcriptional regulator
J4N44_RS10815	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
J4N44_RS10830	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J4N44_RS10835	COG3108	Peptidase M15
J4N44_RS10840	COG2989	Protein conserved in bacteria
J4N44_RS10865	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
J4N44_RS10875	COG4235	cytochrome complex assembly
J4N44_RS10875	COG3088	subunit of a heme lyase
J4N44_RS10885	COG1138	Cytochrome C-type biogenesis protein
J4N44_RS10890	COG3301	Polysulphide reductase, NrfD
J4N44_RS10895	COG0437	4 iron, 4 sulfur cluster binding
J4N44_RS10905	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
J4N44_RS10925	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
J4N44_RS10930	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
J4N44_RS10935	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
J4N44_RS10945	COG1058	Belongs to the CinA family
J4N44_RS10945	COG1546	Belongs to the CinA family
J4N44_RS10960	COG0019	diaminopimelate decarboxylase activity
J4N44_RS11000	COG0322	excinuclease ABC activity
J4N44_RS11005	COG2197	response regulator
J4N44_RS11010	COG0417	DNA replication proofreading
J4N44_RS11030	COG1187	pseudouridine synthase activity
J4N44_RS11040	COG0009	L-threonylcarbamoyladenylate synthase
J4N44_RS11045	COG0613	PHP domain protein
J4N44_RS11055	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
J4N44_RS11060	COG0512	Glutamine amidotransferase of anthranilate synthase
J4N44_RS11070	COG0134	indole-3-glycerol-phosphate synthase activity
J4N44_RS11070	COG0135	phosphoribosylanthranilate isomerase activity
J4N44_RS11080	COG0159	tryptophan synthase activity
J4N44_RS11085	COG1301	dicarboxylic acid transport
J4N44_RS11110	COG1607	acyl-coa hydrolase
J4N44_RS11115	COG2350	Protein conserved in bacteria
J4N44_RS11145	COG5001	Diguanylate cyclase
J4N44_RS11145	COG1716	ATPase activity
J4N44_RS11150	COG1032	radical SAM domain protein
J4N44_RS11170	COG0446	pyridine nucleotide-disulphide oxidoreductase
J4N44_RS11185	COG2964	Protein conserved in bacteria
J4N44_RS11190	COG0840	transmembrane signaling receptor activity
J4N44_RS11200	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
J4N44_RS11205	COG0463	Glycosyl transferase, family 2
J4N44_RS11210	COG0745	RESPONSE REGULATOR receiver
J4N44_RS11215	COG5002	protein histidine kinase activity
J4N44_RS11215	COG3850	Histidine kinase
J4N44_RS11250	COG1846	Transcriptional regulator
J4N44_RS11295	COG1136	(ABC) transporter
J4N44_RS11295	COG0577	efflux transmembrane transporter activity
J4N44_RS11300	COG0577	efflux transmembrane transporter activity
J4N44_RS11300	COG1136	(ABC) transporter
J4N44_RS11305	COG0577	efflux transmembrane transporter activity
J4N44_RS11330	COG3153	acetyltransferase
J4N44_RS11355	COG3118	belongs to the thioredoxin family
J4N44_RS11360	COG4232	protein-disulfide reductase activity
J4N44_RS11375	COG2995	paraquat-inducible protein a
J4N44_RS11380	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
J4N44_RS11380	COG3008	intermembrane lipid transfer
J4N44_RS11385	COG3009	Protein conserved in bacteria
J4N44_RS11440	COG4166	transmembrane transport
J4N44_RS11450	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
J4N44_RS11455	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
J4N44_RS11465	COG0539	negative regulation of cytoplasmic translation
J4N44_RS11475	COG0616	signal peptide processing
J4N44_RS11480	COG1028	Short-chain dehydrogenase reductase Sdr
J4N44_RS11500	COG0835	chemotaxis
J4N44_RS11500	COG0784	Response regulator, receiver
J4N44_RS11505	COG1940	carbohydrate kinase activity
J4N44_RS11515	COG4667	esterase of the alpha-beta hydrolase superfamily
J4N44_RS11530	COG0733	neurotransmitter:sodium symporter activity
J4N44_RS11545	COG1263	PTS System
J4N44_RS11545	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J4N44_RS11550	COG0084	hydrolase, TatD family'
J4N44_RS11565	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
J4N44_RS11595	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
J4N44_RS11610	COG1399	metal-binding, possibly nucleic acid-binding protein
J4N44_RS11615	COG0424	maF-like protein
J4N44_RS11620	COG0564	pseudouridine synthase activity
J4N44_RS11630	COG1530	ribonuclease E activity
J4N44_RS11635	COG0659	secondary active sulfate transmembrane transporter activity
J4N44_RS11640	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
J4N44_RS11645	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
J4N44_RS11675	COG2186	Transcriptional regulator
J4N44_RS11685	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
J4N44_RS11690	COG0653	protein targeting
J4N44_RS11695	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
J4N44_RS11700	COG3706	GGDEF domain
J4N44_RS11705	COG0366	Alpha amylase catalytic
J4N44_RS11710	COG1122	ATPase activity
J4N44_RS11715	COG4120	Belongs to the binding-protein-dependent transport system permease family
J4N44_RS11735	COG0857	belongs to the CobB CobQ family
J4N44_RS11735	COG0280	phosphate acetyltransferase
J4N44_RS11740	COG3174	membrane
J4N44_RS11745	COG0435	Glutathione S-transferase
J4N44_RS11755	COG0444	Belongs to the ABC transporter superfamily
J4N44_RS11760	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J4N44_RS11765	COG0601	transmembrane transport
J4N44_RS11775	COG0314	molybdopterin synthase activity
J4N44_RS11780	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
J4N44_RS11790	COG0521	Mo-molybdopterin cofactor biosynthetic process
J4N44_RS11795	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
J4N44_RS11800	COG0391	Required for morphogenesis under gluconeogenic growth conditions
J4N44_RS11815	COG0556	nucleotide-excision repair
J4N44_RS11825	COG1882	Formate acetyltransferase
J4N44_RS11830	COG4657	Part of a membrane complex involved in electron transport
J4N44_RS11840	COG4656	Part of a membrane complex involved in electron transport
J4N44_RS11845	COG4658	electron transport chain
J4N44_RS11850	COG4659	FMN binding
J4N44_RS11855	COG4660	Part of a membrane complex involved in electron transport
J4N44_RS11860	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
J4N44_RS11865	COG0346	lactoylglutathione lyase activity
J4N44_RS11875	COG2885	chlorophyll binding
J4N44_RS11885	COG2056	Na+-H+ antiporter family
J4N44_RS11895	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
J4N44_RS11915	COG1454	alcohol dehydrogenase
J4N44_RS11915	COG1012	belongs to the aldehyde dehydrogenase family
J4N44_RS11920	COG2095	MarC family integral membrane protein
J4N44_RS11925	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J4N44_RS11930	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
J4N44_RS11935	COG1757	Na H antiporter
J4N44_RS11960	COG3083	sulfuric ester hydrolase activity
J4N44_RS11975	COG0123	including yeast histone deacetylase and acetoin utilization protein
J4N44_RS11990	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
J4N44_RS11995	COG0778	Nitroreductase
J4N44_RS12000	COG1902	pentaerythritol trinitrate reductase activity
J4N44_RS12000	COG0446	pyridine nucleotide-disulphide oxidoreductase
J4N44_RS12005	COG0616	signal peptide processing
J4N44_RS12010	COG0252	asparaginase activity
J4N44_RS12015	COG3139	Protein of unknown function (DUF1315)
J4N44_RS12025	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J4N44_RS12030	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
J4N44_RS12050	COG2226	methyltransferase
J4N44_RS12070	COG1785	Belongs to the alkaline phosphatase family
J4N44_RS12080	COG0346	lactoylglutathione lyase activity
J4N44_RS12085	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
J4N44_RS12090	COG0668	transmembrane transport
J4N44_RS12095	COG2261	transglycosylase associated protein
J4N44_RS12105	COG2983	Belongs to the UPF0260 family
J4N44_RS12125	COG0251	oxidation-reduction process
J4N44_RS12130	COG0814	amino acid
J4N44_RS12135	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
J4N44_RS12140	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
J4N44_RS12150	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
J4N44_RS12160	COG2832	Protein of unknown function (DUF454)
J4N44_RS12165	COG0745	RESPONSE REGULATOR receiver
J4N44_RS12170	COG0583	DNA-binding transcription factor activity
J4N44_RS12175	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
J4N44_RS12180	COG1286	toxin biosynthetic process
J4N44_RS12185	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
J4N44_RS12190	COG0285	dihydrofolate synthase activity
J4N44_RS12210	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
J4N44_RS12215	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
J4N44_RS12220	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
J4N44_RS12240	COG3101	peptidyl-lysine hydroxylation
J4N44_RS12245	COG2860	membrane
J4N44_RS12255	COG2890	protein-(glutamine-N5) methyltransferase activity
J4N44_RS12265	COG2062	phosphohistidine phosphatase, SixA
J4N44_RS12285	COG0183	Belongs to the thiolase family
J4N44_RS12305	COG2067	long-chain fatty acid transport protein
J4N44_RS12310	COG2853	Lipoprotein
J4N44_RS12315	COG3088	subunit of a heme lyase
J4N44_RS12315	COG4235	cytochrome complex assembly
J4N44_RS12325	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J4N44_RS12330	COG1138	Cytochrome C-type biogenesis protein
J4N44_RS12345	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
J4N44_RS12350	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
J4N44_RS12355	COG4133	protoheme IX ABC transporter activity
J4N44_RS12365	COG0835	chemotaxis
J4N44_RS12375	COG1192	Involved in chromosome partitioning
J4N44_RS12380	COG2201	protein-glutamate methylesterase activity
J4N44_RS12385	COG0643	Histidine kinase
J4N44_RS12385	COG0784	Response regulator, receiver
J4N44_RS12385	COG2198	Histidine kinase
J4N44_RS12390	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
J4N44_RS12425	COG1684	flagellar biosynthetic protein fliR
J4N44_RS12430	COG1987	bacterial-type flagellum assembly
J4N44_RS12485	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
J4N44_RS12495	COG1677	Flagellar hook-basal body complex protein FliE
J4N44_RS12515	COG1516	flagellar protein fliS
J4N44_RS12525	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
J4N44_RS12530	COG1334	flagellar protein FlaG
J4N44_RS12535	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
J4N44_RS12545	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
J4N44_RS12550	COG2211	Major facilitator Superfamily
J4N44_RS12555	COG1486	melibiose metabolic process
J4N44_RS12560	COG2169	Transcriptional regulator
J4N44_RS12565	COG2837	iron assimilation
J4N44_RS12590	COG1393	Belongs to the ArsC family
J4N44_RS12610	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
J4N44_RS12615	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J4N44_RS12620	COG2716	regulation of RNA biosynthetic process
J4N44_RS12625	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
J4N44_RS12640	COG4783	chaperone-mediated protein folding
J4N44_RS12645	COG1393	Belongs to the ArsC family
J4N44_RS12665	COG2233	PERMEase
J4N44_RS12670	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
J4N44_RS12675	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
J4N44_RS12680	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
J4N44_RS12685	COG0121	glutamine amidotransferase
J4N44_RS12690	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
J4N44_RS12715	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
J4N44_RS12725	COG2226	methyltransferase
J4N44_RS12735	COG0741	lytic transglycosylase activity
J4N44_RS12735	COG1388	LysM domain
J4N44_RS12750	COG0347	Belongs to the P(II) protein family
J4N44_RS12770	COG0587	DNA-directed DNA polymerase activity
J4N44_RS12795	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J4N44_RS12800	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
J4N44_RS12810	COG0750	zinc metalloprotease
J4N44_RS12820	COG0575	Belongs to the CDS family
J4N44_RS12825	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
J4N44_RS12850	COG0024	Methionine aminopeptidase
J4N44_RS12865	COG0564	pseudouridine synthase activity
J4N44_RS12870	COG3098	single-species biofilm formation
J4N44_RS12905	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J4N44_RS12930	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
J4N44_RS12945	COG1720	tRNA m6t6A37 methyltransferase activity
J4N44_RS12970	COG0733	neurotransmitter:sodium symporter activity
J4N44_RS12985	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
J4N44_RS12990	COG0514	ATP-dependent DNA helicase (RecQ)
J4N44_RS12995	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
J4N44_RS13010	COG1477	protein flavinylation
J4N44_RS13020	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
J4N44_RS13045	COG0271	Belongs to the BolA IbaG family
J4N44_RS13075	COG1595	DNA-templated transcription, initiation
J4N44_RS13090	COG3248	Nucleoside-binding outer membrane protein
J4N44_RS13095	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
J4N44_RS13100	COG0693	protein deglycase activity
J4N44_RS13105	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
J4N44_RS13110	COG2166	iron-sulfur cluster assembly
J4N44_RS13115	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
J4N44_RS13120	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
J4N44_RS13130	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
J4N44_RS13130	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
J4N44_RS13150	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
J4N44_RS13155	COG1074	ATP-dependent DNA helicase activity
J4N44_RS13160	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
J4N44_RS13180	COG3141	response to X-ray
J4N44_RS13195	COG2171	N-acyltransferase activity
J4N44_RS13200	COG0584	glycerophosphoryl diester phosphodiesterase
J4N44_RS13205	COG2271	Major facilitator Superfamily
J4N44_RS13210	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
J4N44_RS13220	COG1349	DNA-binding transcription factor activity
J4N44_RS13225	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
J4N44_RS13250	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J4N44_RS13265	COG2017	converts alpha-aldose to the beta-anomer
J4N44_RS13280	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
J4N44_RS13285	COG0768	penicillin binding
J4N44_RS13295	COG1609	Transcriptional regulator
J4N44_RS13300	COG3250	beta-galactosidase activity
J4N44_RS13305	COG2731	YhcH YjgK YiaL family protein
J4N44_RS13310	COG0531	amino acid
J4N44_RS13315	COG0583	DNA-binding transcription factor activity
J4N44_RS13375	COG4964	Belongs to the GSP D family
J4N44_RS13400	COG2169	Transcriptional regulator
J4N44_RS13405	COG1022	Amp-dependent synthetase and ligase
J4N44_RS13415	COG0583	DNA-binding transcription factor activity
J4N44_RS13420	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
J4N44_RS13425	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
J4N44_RS13435	COG0560	Phosphoserine phosphatase
J4N44_RS13445	COG0813	purine-nucleoside phosphorylase activity
J4N44_RS13455	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
J4N44_RS13465	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
J4N44_RS13470	COG0084	hydrolase, TatD family'
J4N44_RS13480	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
J4N44_RS13485	COG3706	GGDEF domain
J4N44_RS13505	COG3153	acetyltransferase
J4N44_RS13510	COG3154	lipid carrier protein
J4N44_RS13520	COG0826	peptidase U32
J4N44_RS13525	COG0826	peptidase U32
J4N44_RS13530	COG0534	Mate efflux family protein
J4N44_RS13550	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
J4N44_RS13570	COG0195	Participates in both transcription termination and antitermination
J4N44_RS13590	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
J4N44_RS13600	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
J4N44_RS13605	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
J4N44_RS13615	COG1534	Rna-binding protein
J4N44_RS13620	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
J4N44_RS13625	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
J4N44_RS13630	COG2027	D-alanyl-D-alanine carboxypeptidase
J4N44_RS13640	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
J4N44_RS13645	COG0739	heme binding
J4N44_RS13660	COG0316	Belongs to the HesB IscA family
J4N44_RS13670	COG0628	permease
J4N44_RS13685	COG2205	protein histidine kinase activity
J4N44_RS13685	COG2198	Histidine kinase
J4N44_RS13685	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J4N44_RS13685	COG0784	Response regulator, receiver
J4N44_RS13690	COG0747	negative chemotaxis
J4N44_RS13700	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J4N44_RS13705	COG0444	Belongs to the ABC transporter superfamily
J4N44_RS13710	COG4608	Belongs to the ABC transporter superfamily
J4N44_RS13720	COG2971	BadF BadG BcrA BcrD
J4N44_RS13735	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
J4N44_RS13740	COG3842	ATPase activity
J4N44_RS13750	COG1840	ABC-type Fe3 transport system, periplasmic component
J4N44_RS13755	COG0004	ammonium transporteR
J4N44_RS13770	COG1049	propionate catabolic process, 2-methylcitrate cycle
J4N44_RS13775	COG1752	Esterase of the alpha-beta hydrolase superfamily
J4N44_RS13780	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J4N44_RS13785	COG1643	Atp-dependent helicase
J4N44_RS13800	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
J4N44_RS13810	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
J4N44_RS13825	COG1560	Kdo2-lipid A biosynthetic process
J4N44_RS13830	COG0842	Transport permease protein
J4N44_RS13835	COG1131	(ABC) transporter
J4N44_RS13840	COG0659	secondary active sulfate transmembrane transporter activity
J4N44_RS13845	COG0288	reversible hydration of carbon dioxide
J4N44_RS13860	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J4N44_RS13865	COG0508	dehydrogenase complex catalyzes the overall conversion of
J4N44_RS13870	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
J4N44_RS13875	COG2186	Transcriptional regulator
J4N44_RS13895	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
J4N44_RS13900	COG1459	type II secretion system
J4N44_RS13910	COG0237	dephospho-CoA kinase activity
J4N44_RS13915	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
J4N44_RS13920	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
J4N44_RS13945	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
J4N44_RS13950	COG4137	Cytochrome C assembly protein
J4N44_RS13955	COG4536	flavin adenine dinucleotide binding
J4N44_RS13975	COG0612	Peptidase, M16
J4N44_RS13980	COG1238	metal cluster binding
J4N44_RS13990	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
J4N44_RS13995	COG0511	ligase activity, forming carbon-carbon bonds
J4N44_RS13995	COG5016	pyruvate
J4N44_RS14000	COG3630	sodium ion export across plasma membrane
J4N44_RS14060	COG0527	aspartate kinase activity
J4N44_RS14075	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
J4N44_RS14080	COG1546	Belongs to the CinA family
J4N44_RS14090	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
J4N44_RS14120	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
J4N44_RS14130	COG0148	phosphopyruvate hydratase activity
J4N44_RS14140	COG3956	TIGRFAM MazG family protein
J4N44_RS14145	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
J4N44_RS14165	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
J4N44_RS14170	COG1381	Involved in DNA repair and RecF pathway recombination
J4N44_RS14175	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
J4N44_RS14195	COG3086	response to oxidative stress
J4N44_RS14210	COG1595	DNA-templated transcription, initiation
J4N44_RS14215	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
J4N44_RS14225	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
J4N44_RS14245	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J4N44_RS14250	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J4N44_RS14260	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
J4N44_RS14270	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
J4N44_RS14280	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
J4N44_RS14290	COG0583	DNA-binding transcription factor activity
J4N44_RS14305	COG0668	transmembrane transport
J4N44_RS14310	COG0191	fructose-bisphosphate aldolase activity
J4N44_RS14330	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
J4N44_RS14350	COG2356	endonuclease I
J4N44_RS14355	COG1385	rRNA (uridine-N3-)-methyltransferase activity
J4N44_RS14360	COG0189	ligase activity
J4N44_RS14365	COG1678	Uncharacterized ACR, COG1678
J4N44_RS14370	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
J4N44_RS14385	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
J4N44_RS14390	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
J4N44_RS14395	COG0762	integral membrane protein
J4N44_RS14410	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
J4N44_RS14415	COG0635	Involved in the biosynthesis of porphyrin-containing compound
J4N44_RS14515	COG1012	belongs to the aldehyde dehydrogenase family
J4N44_RS14565	COG3437	response regulator, receiver
J4N44_RS14580	COG1486	melibiose metabolic process
J4N44_RS14585	COG1447	Phosphotransferase system cellobiose-specific component IIA
J4N44_RS14595	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
J4N44_RS14615	COG1028	Short-chain dehydrogenase reductase Sdr
J4N44_RS14625	COG0795	lipopolysaccharide-transporting ATPase activity
J4N44_RS14630	COG0795	lipopolysaccharide-transporting ATPase activity
J4N44_RS14640	COG2927	DNA polymerase III (CHI subunit)
J4N44_RS14645	COG0525	valine-tRNA ligase activity
J4N44_RS14655	COG0456	acetyltransferase
J4N44_RS14690	COG0251	oxidation-reduction process
J4N44_RS14695	COG0204	Acyl-transferase
J4N44_RS14705	COG5007	Belongs to the BolA IbaG family
J4N44_RS14715	COG2854	intermembrane phospholipid transfer
J4N44_RS14720	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
J4N44_RS14725	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
J4N44_RS14730	COG1127	ABC transporter
J4N44_RS14740	COG0517	IMP dehydrogenase activity
J4N44_RS14740	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
J4N44_RS14750	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
J4N44_RS14755	COG1137	ATPase activity
J4N44_RS14765	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
J4N44_RS14770	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4N44_RS14780	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4N44_RS14785	COG2239	Acts as a magnesium transporter
J4N44_RS14790	COG0312	modulator of DNA gyrase
J4N44_RS14800	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
J4N44_RS14805	COG0564	pseudouridine synthase activity
J4N44_RS14820	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
J4N44_RS14825	COG0312	modulator of DNA gyrase
J4N44_RS14830	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
J4N44_RS14835	COG3164	Protein of unknown function
J4N44_RS14845	COG0424	maF-like protein
J4N44_RS14850	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
J4N44_RS14855	COG1792	Involved in formation and maintenance of cell shape
J4N44_RS14860	COG1077	Cell shape determining protein MreB Mrl
J4N44_RS14895	COG2165	general secretion pathway protein
J4N44_RS14905	COG1459	type II secretion system
J4N44_RS14910	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
J4N44_RS14920	COG3409	Peptidoglycan-binding domain 1 protein
J4N44_RS14920	COG3267	Type II secretory pathway component ExeA
J4N44_RS14945	COG2199	diguanylate cyclase activity
J4N44_RS14945	COG2200	EAL domain
J4N44_RS14950	COG0629	single-stranded DNA binding
J4N44_RS14965	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
J4N44_RS14975	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
J4N44_RS14980	COG0527	aspartate kinase activity
J4N44_RS14985	COG0646	methionine synthase
J4N44_RS14985	COG1410	methionine synthase
J4N44_RS15050	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
J4N44_RS15070	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
J4N44_RS15075	COG0735	belongs to the Fur family
J4N44_RS15090	COG0432	Pfam Uncharacterised protein family UPF0047
J4N44_RS15100	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
J4N44_RS15105	COG0305	Participates in initiation and elongation during chromosome replication
J4N44_RS15125	COG0360	Binds together with S18 to 16S ribosomal RNA
J4N44_RS15130	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
J4N44_RS15135	COG0338	D12 class N6 adenine-specific DNA methyltransferase
J4N44_RS15180	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
J4N44_RS15190	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
J4N44_RS15190	COG0678	peroxiredoxin activity
J4N44_RS15195	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J4N44_RS15205	COG0165	Argininosuccinate lyase
J4N44_RS15205	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
J4N44_RS15220	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
J4N44_RS15230	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
J4N44_RS15240	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
J4N44_RS15245	COG0460	homoserine dehydrogenase
J4N44_RS15245	COG0527	aspartate kinase activity
J4N44_RS15250	COG0626	cystathionine gamma-synthase activity
J4N44_RS15260	COG0281	malic enzyme
J4N44_RS15270	COG2906	2 iron, 2 sulfur cluster binding
J4N44_RS15280	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
J4N44_RS15295	COG2168	tRNA wobble position uridine thiolation
J4N44_RS15300	COG2923	Belongs to the DsrF TusC family
J4N44_RS15305	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
J4N44_RS15315	COG0545	Peptidyl-prolyl cis-trans isomerase
J4N44_RS15330	COG1446	asparaginase
J4N44_RS15335	COG1047	Peptidyl-prolyl cis-trans
J4N44_RS15350	COG2249	NAD(P)H dehydrogenase (quinone) activity
J4N44_RS15355	COG0488	(ABC) transporter
J4N44_RS15365	COG0429	hydrolase of the alpha beta-hydrolase fold
J4N44_RS15375	COG3954	Phosphoribulokinase
J4N44_RS15380	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J4N44_RS15400	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
J4N44_RS15430	COG0546	phosphoglycolate phosphatase activity
J4N44_RS15435	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J4N44_RS15440	COG0557	exoribonuclease II activity
J4N44_RS15450	COG1017	nitric oxide dioxygenase activity
J4N44_RS15450	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
J4N44_RS15455	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
J4N44_RS15460	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
J4N44_RS15465	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
J4N44_RS15470	COG0330	HflC and HflK could
J4N44_RS15475	COG0330	HflC and HflK could
J4N44_RS15480	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
J4N44_RS15495	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
J4N44_RS15500	COG0860	N-Acetylmuramoyl-L-alanine amidase
J4N44_RS15505	COG0802	atpase or kinase
J4N44_RS15510	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
J4N44_RS15580	COG1162	GTPase activity
J4N44_RS15590	COG0471	metal ion transport
J4N44_RS15595	COG0840	transmembrane signaling receptor activity
J4N44_RS15605	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
J4N44_RS15610	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J4N44_RS15615	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
J4N44_RS15625	COG1045	serine acetyltransferase
J4N44_RS15630	COG4942	peptidase
J4N44_RS15655	COG1053	succinate dehydrogenase
J4N44_RS15660	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
J4N44_RS15690	COG1509	lysine 2,3-aminomutase activity
J4N44_RS15715	COG0534	Mate efflux family protein
J4N44_RS15725	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
J4N44_RS15730	COG3678	ATP-independent chaperone mediated protein folding
J4N44_RS15735	COG0745	RESPONSE REGULATOR receiver
J4N44_RS15740	COG2205	protein histidine kinase activity
J4N44_RS15745	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
J4N44_RS15750	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
J4N44_RS15755	COG3030	protein affecting phage T7 exclusion by the F plasmid
J4N44_RS15760	COG1027	Aspartate ammonia-lyase
J4N44_RS15765	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
J4N44_RS15770	COG4232	protein-disulfide reductase activity
J4N44_RS15780	COG2095	MarC family integral membrane protein
J4N44_RS15790	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J4N44_RS15810	COG0784	Response regulator, receiver
J4N44_RS15810	COG2198	Histidine kinase
J4N44_RS15810	COG2205	protein histidine kinase activity
J4N44_RS15815	COG2814	Major facilitator Superfamily
J4N44_RS15830	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
J4N44_RS15835	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
J4N44_RS15840	COG0511	ligase activity, forming carbon-carbon bonds
J4N44_RS15845	COG0439	Biotin carboxylase
J4N44_RS15855	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
J4N44_RS15860	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
J4N44_RS15865	COG2199	diguanylate cyclase activity
J4N44_RS15915	COG1982	Orn Lys Arg decarboxylase major
J4N44_RS15920	COG0531	amino acid
J4N44_RS15925	COG3710	Transcriptional regulator
J4N44_RS15930	COG0789	Transcriptional regulator
J4N44_RS15940	COG0151	Belongs to the GarS family
J4N44_RS15955	COG1253	flavin adenine dinucleotide binding
J4N44_RS15960	COG3068	Protein conserved in bacteria
J4N44_RS15970	COG1573	uracil-dna glycosylase
J4N44_RS15990	COG2816	NAD+ diphosphatase activity
J4N44_RS15995	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
J4N44_RS16015	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
J4N44_RS16030	COG0250	Participates in transcription elongation, termination and antitermination
J4N44_RS16035	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
J4N44_RS16075	COG0812	UDP-N-acetylmuramate dehydrogenase activity
J4N44_RS16085	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J4N44_RS16185	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J4N44_RS16190	COG0534	Mate efflux family protein
J4N44_RS16205	COG2937	Belongs to the GPAT DAPAT family
J4N44_RS16215	COG3161	chorismate lyase activity
J4N44_RS16220	COG1580	Controls the rotational direction of flagella during chemotaxis
J4N44_RS16225	COG0705	Rhomboid family
J4N44_RS16240	COG2177	Part of the ABC transporter FtsEX involved in
J4N44_RS16245	COG2884	Cell division ATP-binding protein ftsE
J4N44_RS16250	COG0552	protein localization to endoplasmic reticulum
J4N44_RS16250	COG0552	protein localization to endoplasmic reticulum
J4N44_RS16255	COG0742	ribosomal rna small subunit methyltransferase
J4N44_RS16265	COG2095	MarC family integral membrane protein
J4N44_RS16310	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
J4N44_RS16315	COG0640	Transcriptional regulator
J4N44_RS16320	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
J4N44_RS16325	COG1280	lysine exporter protein (LysE YggA)
J4N44_RS16330	COG2267	carboxylic ester hydrolase activity
J4N44_RS16335	COG0561	phosphatase activity
J4N44_RS16350	COG3148	PFAM DTW domain containing protein
J4N44_RS16355	COG2200	EAL domain
J4N44_RS16355	COG3287	FIST C domain
J4N44_RS16355	COG2199	diguanylate cyclase activity
J4N44_RS16360	COG1011	Hydrolase
J4N44_RS16380	COG0019	diaminopimelate decarboxylase activity
J4N44_RS16395	COG3072	Adenylate cyclase
J4N44_RS16405	COG1587	Uroporphyrinogen-III synthase
J4N44_RS16410	COG2959	enzyme of heme biosynthesis
J4N44_RS16415	COG3071	HemY protein
J4N44_RS16455	COG0633	Ferredoxin
J4N44_RS16460	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
J4N44_RS16475	COG3118	belongs to the thioredoxin family
J4N44_RS16490	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
J4N44_RS16500	COG0514	ATP-dependent DNA helicase (RecQ)
J4N44_RS16505	COG2962	Rard protein
J4N44_RS16515	COG1280	lysine exporter protein (LysE YggA)
J4N44_RS16520	COG0405	Gamma-glutamyltransferase
J4N44_RS16525	COG0210	DNA helicase
J4N44_RS16535	COG3220	belongs to the UPF0276 family
J4N44_RS16555	COG2814	Major facilitator Superfamily
J4N44_RS16565	COG0006	proline dipeptidase activity
J4N44_RS16565	COG0006	proline dipeptidase activity
J4N44_RS16580	COG2104	thiamine diphosphate biosynthetic process
J4N44_RS16585	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
J4N44_RS16605	COG2132	Multicopper oxidase
J4N44_RS16645	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
J4N44_RS16655	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
J4N44_RS16670	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
J4N44_RS16675	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
J4N44_RS16680	COG0551	DNA topoisomerase type I activity
J4N44_RS16690	COG0758	DNA mediated transformation
J4N44_RS16710	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
J4N44_RS16710	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
J4N44_RS16715	COG0569	domain protein
J4N44_RS16720	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
J4N44_RS16730	COG1272	protein, Hemolysin III
J4N44_RS16735	COG4326	sporulation control protein
J4N44_RS16745	COG3084	Protein conserved in bacteria
J4N44_RS16755	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
J4N44_RS16760	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
J4N44_RS16765	COG0204	Acyl-transferase
J4N44_RS16775	COG3706	GGDEF domain
J4N44_RS16810	COG0758	DNA mediated transformation
J4N44_RS16835	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
J4N44_RS16850	COG3978	acetolactate synthase activity
J4N44_RS16855	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
J4N44_RS16860	COG0129	dihydroxy-acid dehydratase activity
J4N44_RS16870	COG0583	DNA-binding transcription factor activity
J4N44_RS16875	COG2814	Major facilitator Superfamily
J4N44_RS16885	COG0765	amino acid transport
J4N44_RS16895	COG0355	proton-transporting ATP synthase activity, rotational mechanism
J4N44_RS16905	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
J4N44_RS16930	COG0356	it plays a direct role in the translocation of protons across the membrane
J4N44_RS16935	COG3312	ion transport
J4N44_RS16940	COG1475	DNA binding
J4N44_RS16945	COG1192	Involved in chromosome partitioning
J4N44_RS16955	COG0445	tRNA wobble uridine modification
J4N44_RS16960	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
J4N44_RS16990	COG1126	abc transporter atp-binding protein
J4N44_RS17015	COG1444	tRNA N-acetyltransferase activity
J4N44_RS17020	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
J4N44_RS17025	COG0848	biopolymer transport protein
J4N44_RS17065	COG1595	DNA-templated transcription, initiation
J4N44_RS17095	COG4166	transmembrane transport
J4N44_RS17165	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J4N44_RS17220	COG1132	(ABC) transporter
J4N44_RS17245	COG0800	Aldolase
J4N44_RS17250	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J4N44_RS17255	COG1904	glucuronate isomerase
J4N44_RS17260	COG0246	Mannitol dehydrogenase
J4N44_RS17270	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
J4N44_RS17280	COG2186	Transcriptional regulator
J4N44_RS17285	COG1312	Catalyzes the dehydration of D-mannonate
J4N44_RS17290	COG3655	Transcriptional regulator
J4N44_RS17305	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
J4N44_RS17310	COG1595	DNA-templated transcription, initiation
J4N44_RS17320	COG0513	Belongs to the DEAD box helicase family
J4N44_RS17325	COG3713	MltA-interacting MipA family protein
J4N44_RS17335	COG2153	protein acetylation
J4N44_RS17340	COG2258	MOSC domain
J4N44_RS17355	COG1522	sequence-specific DNA binding
J4N44_RS17375	COG0346	lactoylglutathione lyase activity
J4N44_RS17420	COG0366	Alpha amylase catalytic
J4N44_RS17425	COG0583	DNA-binding transcription factor activity
J4N44_RS17460	COG3734	2-keto-3-deoxy-galactonokinase
J4N44_RS17465	COG0800	Aldolase
J4N44_RS17470	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
J4N44_RS17475	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
J4N44_RS17475	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
J4N44_RS17480	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
J4N44_RS17480	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
J4N44_RS17485	COG4948	Mandelate Racemase Muconate Lactonizing
J4N44_RS17490	COG0129	dihydroxy-acid dehydratase activity
J4N44_RS17500	COG3634	alkyl hydroperoxide reductase activity
J4N44_RS17515	COG1846	Transcriptional regulator
J4N44_RS17520	COG1764	response to oxidative stress
J4N44_RS17535	COG0840	transmembrane signaling receptor activity
J4N44_RS17540	COG0612	Peptidase, M16
J4N44_RS17565	COG0739	heme binding
J4N44_RS17590	COG4604	ABC transporter, ATP-binding protein
J4N44_RS17595	COG4605	iron ion homeostasis
J4N44_RS17600	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J4N44_RS17605	COG4607	ABC-type enterochelin transport system periplasmic component
J4N44_RS17610	COG0583	DNA-binding transcription factor activity
J4N44_RS17615	COG4771	TonB-dependent receptor
J4N44_RS17635	COG2814	Major facilitator Superfamily
J4N44_RS17645	COG1609	Transcriptional regulator
J4N44_RS17670	COG1760	l-serine dehydratase
J4N44_RS17680	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
J4N44_RS17710	COG2199	diguanylate cyclase activity
J4N44_RS17710	COG2203	Gaf domain
J4N44_RS17735	COG0366	Alpha amylase catalytic
J4N44_RS17740	COG2356	endonuclease I
J4N44_RS17745	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J4N44_RS17790	COG0456	acetyltransferase
J4N44_RS17810	COG1028	Short-chain dehydrogenase reductase Sdr
J4N44_RS17820	COG3005	denitrification pathway
J4N44_RS17825	COG0243	molybdopterin cofactor binding
J4N44_RS17830	COG0671	phosphoesterase, PA-phosphatase related
J4N44_RS17845	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
J4N44_RS17850	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
J4N44_RS17855	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J4N44_RS17860	COG1116	anion transmembrane transporter activity
J4N44_RS17865	COG0351	phosphomethylpyrimidine kinase
J4N44_RS17870	COG0312	modulator of DNA gyrase
J4N44_RS17875	COG0312	modulator of DNA gyrase
J4N44_RS17935	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
J4N44_RS17945	COG0584	glycerophosphoryl diester phosphodiesterase
J4N44_RS17950	COG0039	L-malate dehydrogenase activity
J4N44_RS17955	COG0745	RESPONSE REGULATOR receiver
J4N44_RS17975	COG0811	peptide transport
J4N44_RS17980	COG0811	peptide transport
J4N44_RS17985	COG0848	biopolymer transport protein
J4N44_RS18030	COG0803	Belongs to the bacterial solute-binding protein 9 family
J4N44_RS18035	COG1121	(ABC) transporter
J4N44_RS18040	COG1108	ABC-type Mn2 Zn2 transport systems permease components
J4N44_RS18055	COG1770	oligopeptidase
J4N44_RS18060	COG2814	Major facilitator Superfamily
J4N44_RS18065	COG0010	Belongs to the arginase family
J4N44_RS18070	COG1166	arginine decarboxylase activity
J4N44_RS18080	COG4067	protein conserved in archaea
J4N44_RS18080	COG0189	ligase activity
J4N44_RS18085	COG0189	ligase activity
J4N44_RS18105	COG0583	DNA-binding transcription factor activity
J4N44_RS18145	COG1114	Component of the transport system for branched-chain amino acids
J4N44_RS18160	COG0579	oxidoreductase
J4N44_RS18165	COG3179	chitinase
J4N44_RS18185	COG3033	Beta-eliminating lyase
J4N44_RS18200	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
J4N44_RS18205	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
J4N44_RS18225	COG3706	GGDEF domain
J4N44_RS18240	COG3706	GGDEF domain
J4N44_RS18245	COG0415	Belongs to the DNA photolyase family
J4N44_RS18250	COG3046	protein related to deoxyribodipyrimidine photolyase
J4N44_RS18265	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J4N44_RS18265	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J4N44_RS18270	COG1765	OsmC-like protein
J4N44_RS18320	COG1011	Hydrolase
J4N44_RS18355	COG3240	lipase activity
J4N44_RS18385	COG1609	Transcriptional regulator
J4N44_RS18395	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
J4N44_RS18400	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
J4N44_RS18405	COG1840	ABC-type Fe3 transport system, periplasmic component
J4N44_RS18410	COG3842	ATPase activity
J4N44_RS18435	COG2990	Protein conserved in bacteria
J4N44_RS18445	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J4N44_RS18450	COG2866	Carboxypeptidase
J4N44_RS18460	COG0583	DNA-binding transcription factor activity
J4N44_RS18485	COG3104	oligopeptide transport
J4N44_RS18490	COG1760	l-serine dehydratase
J4N44_RS18515	COG0741	lytic transglycosylase activity
J4N44_RS18515	COG1388	LysM domain
J4N44_RS18535	COG1815	bacterial-type flagellum-dependent cell motility
J4N44_RS18540	COG1558	bacterial-type flagellum-dependent cell motility
J4N44_RS18550	COG1749	Flagellar hook protein flgE
J4N44_RS18555	COG4787	bacterial-type flagellum-dependent cell motility
J4N44_RS18560	COG4786	Flagellar basal body rod
J4N44_RS18565	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
J4N44_RS18570	COG1706	bacterial-type flagellum-dependent cell motility
J4N44_RS18580	COG1256	bacterial-type flagellum assembly
J4N44_RS18580	COG4786	Flagellar basal body rod
J4N44_RS18620	COG2226	methyltransferase
J4N44_RS18640	COG0672	)-iron permease
J4N44_RS18655	COG1136	(ABC) transporter
J4N44_RS18655	COG0577	efflux transmembrane transporter activity
J4N44_RS18665	COG1136	(ABC) transporter
J4N44_RS18680	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
J4N44_RS18730	COG1360	Flagellar Motor Protein
J4N44_RS18735	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
J4N44_RS18740	COG1191	sigma factor activity
J4N44_RS18745	COG1580	Controls the rotational direction of flagella during chemotaxis
J4N44_RS18760	COG1516	flagellar protein fliS
J4N44_RS18765	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
J4N44_RS18775	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
J4N44_RS18790	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
J4N44_RS18800	COG1987	bacterial-type flagellum assembly
J4N44_RS18865	COG2200	EAL domain
J4N44_RS18950	COG0346	lactoylglutathione lyase activity
J4N44_RS18975	COG0745	RESPONSE REGULATOR receiver
J4N44_RS19000	COG0156	8-amino-7-oxononanoate synthase activity
J4N44_RS19005	COG1063	alcohol dehydrogenase
J4N44_RS19025	COG3338	carbonate dehydratase activity
J4N44_RS19060	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J4N44_RS19070	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J4N44_RS19105	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
J4N44_RS19115	COG0318	PFAM AMP-dependent synthetase and ligase
J4N44_RS19120	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
J4N44_RS19150	COG0786	glutamate:sodium symporter activity
J4N44_RS19155	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
J4N44_RS19165	COG1538	Outer membrane efflux protein
J4N44_RS19175	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J4N44_RS19180	COG0583	DNA-binding transcription factor activity
J4N44_RS19195	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
J4N44_RS19200	COG2197	response regulator
J4N44_RS19210	COG0574	Belongs to the PEP-utilizing enzyme family
J4N44_RS19210	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
J4N44_RS19220	COG0252	asparaginase activity
J4N44_RS19230	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
J4N44_RS19235	COG0583	DNA-binding transcription factor activity
J4N44_RS19255	COG3122	Protein conserved in bacteria
J4N44_RS19270	COG1902	pentaerythritol trinitrate reductase activity
J4N44_RS19280	COG2814	Major facilitator Superfamily
J4N44_RS19285	COG1028	Short-chain dehydrogenase reductase Sdr
J4N44_RS19310	COG0583	DNA-binding transcription factor activity
J4N44_RS19320	COG0513	Belongs to the DEAD box helicase family
J4N44_RS19340	COG0095	Lipoate-protein ligase
J4N44_RS19360	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J4N44_RS19365	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
J4N44_RS19365	COG2207	Transcriptional regulator
J4N44_RS19370	COG0583	DNA-binding transcription factor activity
J4N44_RS19380	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J4N44_RS19415	COG1566	PFAM secretion protein HlyD family protein
J4N44_RS19420	COG0583	DNA-binding transcription factor activity
J4N44_RS19435	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4N44_RS19435	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4N44_RS19435	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4N44_RS19440	COG2207	Transcriptional regulator
J4N44_RS19450	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4N44_RS19455	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4N44_RS19460	COG0583	DNA-binding transcription factor activity
J4N44_RS19470	COG2084	Dehydrogenase
J4N44_RS19475	COG0753	catalase activity
J4N44_RS19485	COG2130	NADP-dependent
J4N44_RS19490	COG1309	transcriptional regulator
J4N44_RS19525	COG0438	transferase activity, transferring glycosyl groups
J4N44_RS19535	COG0489	protein tyrosine kinase activity
J4N44_RS19535	COG3206	protein involved in exopolysaccharide biosynthesis
J4N44_RS19555	COG3842	ATPase activity
J4N44_RS19565	COG1175	transmembrane transport
J4N44_RS19570	COG3833	ABC-type maltose transport systems, permease component
J4N44_RS19615	COG0741	lytic transglycosylase activity
J4N44_RS19630	COG4753	response regulator
J4N44_RS19630	COG2207	Transcriptional regulator
J4N44_RS19640	COG2354	Protein conserved in bacteria
J4N44_RS19650	COG0401	homolog of Blt101
J4N44_RS19655	COG3217	Mosc domain protein beta barrel domain protein
J4N44_RS19655	COG0633	Ferredoxin
J4N44_RS19655	COG3217	Mosc domain protein beta barrel domain protein
J4N44_RS19655	COG0633	Ferredoxin
J4N44_RS19665	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
J4N44_RS19705	COG0583	DNA-binding transcription factor activity
J4N44_RS19735	COG1335	isochorismatase
J4N44_RS19740	COG4977	sequence-specific DNA binding
J4N44_RS19755	COG2194	sulfuric ester hydrolase activity
J4N44_RS19760	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
J4N44_RS19770	COG2205	protein histidine kinase activity
J4N44_RS19775	COG0745	RESPONSE REGULATOR receiver
J4N44_RS19780	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
J4N44_RS19785	COG4948	Mandelate Racemase Muconate Lactonizing
J4N44_RS19790	COG1053	succinate dehydrogenase
J4N44_RS19790	COG3976	FMN-binding domain protein
J4N44_RS19805	COG4221	oxidoreductase activity
J4N44_RS19820	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
J4N44_RS19840	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
J4N44_RS19850	COG2814	Major facilitator Superfamily
J4N44_RS19865	COG1418	mRNA catabolic process
J4N44_RS19880	COG0402	S-adenosylhomocysteine deaminase activity
J4N44_RS19885	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
J4N44_RS19890	COG2239	Acts as a magnesium transporter
J4N44_RS19895	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
J4N44_RS19900	COG1566	PFAM secretion protein HlyD family protein
J4N44_RS19925	COG0745	RESPONSE REGULATOR receiver
J4N44_RS19930	COG2205	protein histidine kinase activity
J4N44_RS19940	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J4N44_RS19945	COG0531	amino acid
J4N44_RS19950	COG1522	sequence-specific DNA binding
J4N44_RS19960	COG0583	DNA-binding transcription factor activity
J4N44_RS19980	COG0784	Response regulator, receiver
J4N44_RS19980	COG2205	protein histidine kinase activity
J4N44_RS19980	COG5002	protein histidine kinase activity
J4N44_RS19985	COG0673	inositol 2-dehydrogenase activity
J4N44_RS19990	COG0534	Mate efflux family protein
J4N44_RS19995	COG2926	Belongs to the UPF0265 family
J4N44_RS20060	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J4N44_RS20065	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J4N44_RS20075	COG1280	lysine exporter protein (LysE YggA)
J4N44_RS20085	COG0183	Belongs to the thiolase family
J4N44_RS20105	COG3005	denitrification pathway
J4N44_RS20125	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
J4N44_RS20130	COG3850	Histidine kinase
J4N44_RS20135	COG2197	response regulator
J4N44_RS20150	COG2195	Cleaves the N-terminal amino acid of tripeptides
J4N44_RS20170	COG0840	transmembrane signaling receptor activity
J4N44_RS20180	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J4N44_RS20210	COG0545	Peptidyl-prolyl cis-trans isomerase
J4N44_RS20220	COG2885	chlorophyll binding
J4N44_RS20240	COG1278	Cold shock
J4N44_RS20245	COG3036	rescue of stalled ribosome
J4N44_RS20255	COG2199	diguanylate cyclase activity
J4N44_RS20275	COG0577	efflux transmembrane transporter activity
J4N44_RS20275	COG1136	(ABC) transporter
J4N44_RS20305	COG1538	Outer membrane efflux protein
J4N44_RS20310	COG0784	Response regulator, receiver
J4N44_RS20310	COG2205	protein histidine kinase activity
J4N44_RS20335	COG0840	transmembrane signaling receptor activity
J4N44_RS20340	COG0783	Belongs to the Dps family
J4N44_RS20350	COG1619	proteins homologs of microcin C7 resistance protein MccF
J4N44_RS20355	COG2133	pyrroloquinoline quinone binding
J4N44_RS20360	COG1454	alcohol dehydrogenase
J4N44_RS20365	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
J4N44_RS20390	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
J4N44_RS20395	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
J4N44_RS20400	COG3186	Phenylalanine-4-hydroxylase
J4N44_RS20430	COG3530	Putative quorum-sensing-regulated virulence factor
J4N44_RS20465	COG1289	transmembrane transporter activity
J4N44_RS20470	COG0210	DNA helicase
J4N44_RS20480	COG1879	ABC-type sugar transport system periplasmic component
J4N44_RS20485	COG2198	Histidine kinase
J4N44_RS20485	COG0784	Response regulator, receiver
J4N44_RS20485	COG2205	protein histidine kinase activity
J4N44_RS20515	COG3119	arylsulfatase activity
J4N44_RS20520	COG3119	arylsulfatase activity
J4N44_RS20530	COG0583	DNA-binding transcription factor activity
J4N44_RS20535	COG3119	arylsulfatase activity
J4N44_RS20540	COG0641	radical SAM
J4N44_RS20545	COG0714	Associated with various cellular activities
J4N44_RS20605	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
J4N44_RS20615	COG0355	proton-transporting ATP synthase activity, rotational mechanism
J4N44_RS20625	COG0583	DNA-binding transcription factor activity
J4N44_RS20630	COG1597	lipid kinase activity
J4N44_RS20635	COG3111	PFAM Bacterial OB fold (BOF) protein
J4N44_RS20655	COG0641	radical SAM
J4N44_RS20680	COG0501	Belongs to the peptidase M48B family
J4N44_RS20685	COG1704	LemA family
J4N44_RS20690	COG3069	C4-dicarboxylate transmembrane transporter activity
J4N44_RS20720	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
J4N44_RS20725	COG0739	heme binding
J4N44_RS20745	COG2885	chlorophyll binding
J4N44_RS20765	COG3501	Rhs element vgr protein
J4N44_RS20790	COG0515	serine threonine protein kinase
J4N44_RS20825	COG1522	sequence-specific DNA binding
J4N44_RS20895	COG0457	Tetratricopeptide repeat
J4N44_RS20900	COG0477	Major facilitator Superfamily
J4N44_RS20900	COG2814	Major facilitator Superfamily
J4N44_RS20905	COG1940	carbohydrate kinase activity
J4N44_RS20910	COG2017	converts alpha-aldose to the beta-anomer
J4N44_RS20915	COG0019	diaminopimelate decarboxylase activity
J4N44_RS20920	COG4264	IucA IucC family
J4N44_RS20945	COG4772	TonB-dependent receptor
J4N44_RS20950	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
J4N44_RS20955	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J4N44_RS20960	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J4N44_RS20965	COG1120	ATPase activity
J4N44_RS20970	COG4771	TonB-dependent receptor
J4N44_RS20980	COG5001	Diguanylate cyclase
J4N44_RS20985	COG0745	RESPONSE REGULATOR receiver
J4N44_RS20990	COG5002	protein histidine kinase activity
J4N44_RS20995	COG4174	ABC transporter (Permease)
J4N44_RS21000	COG4239	(ABC) transporter, permease
J4N44_RS21005	COG4166	transmembrane transport
J4N44_RS21010	COG0444	Belongs to the ABC transporter superfamily
J4N44_RS21015	COG4608	Belongs to the ABC transporter superfamily
J4N44_RS21030	COG0784	Response regulator, receiver
J4N44_RS21030	COG2205	protein histidine kinase activity
J4N44_RS21035	COG5001	Diguanylate cyclase
J4N44_RS21035	COG3300	MHYT domain
J4N44_RS21040	COG2197	response regulator
J4N44_RS21045	COG3706	GGDEF domain
J4N44_RS21055	COG2197	response regulator
J4N44_RS21065	COG0778	Nitroreductase
J4N44_RS21070	COG0835	chemotaxis
J4N44_RS21070	COG0784	Response regulator, receiver
J4N44_RS21075	COG2165	general secretion pathway protein
J4N44_RS21085	COG2962	Rard protein
J4N44_RS21110	COG3278	Belongs to the heme-copper respiratory oxidase family
J4N44_RS21140	COG1024	Enoyl-CoA hydratase
J4N44_RS21145	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
J4N44_RS21150	COG1960	acyl-CoA dehydrogenase activity
J4N44_RS21160	COG0183	Belongs to the thiolase family
J4N44_RS21175	COG1024	Enoyl-CoA hydratase
J4N44_RS21180	COG1024	Enoyl-CoA hydratase
J4N44_RS21190	COG1028	Short-chain dehydrogenase reductase Sdr
J4N44_RS21195	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
J4N44_RS21200	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
J4N44_RS21205	COG1845	cytochrome c oxidase, subunit III
J4N44_RS21210	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
J4N44_RS21230	COG1902	pentaerythritol trinitrate reductase activity
J4N44_RS21230	COG0446	pyridine nucleotide-disulphide oxidoreductase
J4N44_RS21235	COG0671	phosphoesterase, PA-phosphatase related
J4N44_RS21275	COG1132	(ABC) transporter
J4N44_RS21290	COG1733	regulation of RNA biosynthetic process
J4N44_RS21300	COG2176	DNA-directed DNA polymerase activity
J4N44_RS21315	COG0583	DNA-binding transcription factor activity
J4N44_RS21320	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
J4N44_RS21350	COG1201	RNA secondary structure unwinding
J4N44_RS21360	COG0509	glycine decarboxylation via glycine cleavage system
J4N44_RS21365	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
J4N44_RS21375	COG0404	The glycine cleavage system catalyzes the degradation of glycine
J4N44_RS21385	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J4N44_RS21390	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J4N44_RS21420	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4N44_RS21420	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4N44_RS21420	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
J4N44_RS21425	COG1105	Belongs to the carbohydrate kinase PfkB family
J4N44_RS21430	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4N44_RS21430	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4N44_RS21435	COG1609	Transcriptional regulator
J4N44_RS21450	COG2199	diguanylate cyclase activity
J4N44_RS21450	COG2200	EAL domain
J4N44_RS21450	COG2203	Gaf domain
J4N44_RS21455	COG0765	amino acid transport
J4N44_RS21460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J4N44_RS21465	COG0765	amino acid transport
J4N44_RS21470	COG1126	abc transporter atp-binding protein
J4N44_RS21480	COG1979	alcohol dehydrogenase
J4N44_RS21485	COG2207	Transcriptional regulator
J4N44_RS21495	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
J4N44_RS21505	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J4N44_RS21520	COG0784	Response regulator, receiver
J4N44_RS21520	COG3437	response regulator, receiver
J4N44_RS21525	COG0546	phosphoglycolate phosphatase activity
J4N44_RS21545	COG0513	Belongs to the DEAD box helicase family
J4N44_RS21550	COG4943	cyclic-guanylate-specific phosphodiesterase activity
J4N44_RS21565	COG3038	cytochrome b561
J4N44_RS21575	COG2116	formate transmembrane transporter activity
J4N44_RS21580	COG0583	DNA-binding transcription factor activity
J4N44_RS21590	COG3593	DNA synthesis involved in DNA repair
J4N44_RS21595	COG0737	Belongs to the 5'-nucleotidase family
J4N44_RS21615	COG1410	methionine synthase
J4N44_RS21615	COG0646	methionine synthase
J4N44_RS21630	COG2267	carboxylic ester hydrolase activity
J4N44_RS21635	COG2067	long-chain fatty acid transport protein
J4N44_RS21650	COG2050	protein possibly involved in aromatic compounds catabolism
J4N44_RS21685	COG0484	heat shock protein binding
J4N44_RS21695	COG3300	MHYT domain
J4N44_RS21695	COG5001	Diguanylate cyclase
J4N44_RS21700	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
J4N44_RS21710	COG4181	ATPase activity
J4N44_RS21715	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
J4N44_RS21725	COG1984	allophanate hydrolase subunit 2
J4N44_RS21740	COG5002	protein histidine kinase activity
J4N44_RS21740	COG5001	Diguanylate cyclase
J4N44_RS21740	COG3447	MASE1 domain protein
J4N44_RS21745	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
J4N44_RS21755	COG0583	DNA-binding transcription factor activity
J4N44_RS21765	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J4N44_RS21765	COG1042	CoA-binding domain protein
J4N44_RS21765	COG0045	succinate-CoA ligase (ADP-forming) activity
J4N44_RS21785	COG0023	Translation Initiation Factor
J4N44_RS21810	COG3140	Belongs to the UPF0181 family
J4N44_RS21835	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
J4N44_RS21840	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
J4N44_RS21870	COG2203	Gaf domain
J4N44_RS21870	COG5001	Diguanylate cyclase
J4N44_RS21870	COG4251	negative regulation of phosphorylation
J4N44_RS21870	COG3706	GGDEF domain
J4N44_RS21880	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
J4N44_RS21885	COG4149	molybdate abc transporter
J4N44_RS21890	COG0725	ABC transporter, periplasmic molybdate-binding protein
J4N44_RS21900	COG3111	PFAM Bacterial OB fold (BOF) protein
J4N44_RS21910	COG4067	protein conserved in archaea
J4N44_RS21910	COG0189	ligase activity
J4N44_RS21925	COG0534	Mate efflux family protein
J4N44_RS21930	COG0602	queuosine metabolic process
J4N44_RS21935	COG1328	CTP reductase activity
J4N44_RS21995	COG2197	response regulator
J4N44_RS22000	COG3851	Histidine kinase
J4N44_RS22005	COG2271	Major facilitator Superfamily
J4N44_RS22010	COG1482	cell wall glycoprotein biosynthetic process
J4N44_RS22020	COG0628	permease
J4N44_RS22030	COG1566	PFAM secretion protein HlyD family protein
J4N44_RS22055	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
J4N44_RS22060	COG3118	belongs to the thioredoxin family
J4N44_RS22070	COG0745	RESPONSE REGULATOR receiver
J4N44_RS22070	COG3292	Two component regulator propeller
J4N44_RS22070	COG2205	protein histidine kinase activity
J4N44_RS22105	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
J4N44_RS22125	COG2116	formate transmembrane transporter activity
J4N44_RS22135	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
J4N44_RS22140	COG5001	Diguanylate cyclase
J4N44_RS22170	COG0840	transmembrane signaling receptor activity
J4N44_RS22220	COG0277	FAD linked oxidase domain protein
J4N44_RS22225	COG0583	DNA-binding transcription factor activity
J4N44_RS22235	COG2425	protein containing a von Willebrand factor type A (vWA) domain
J4N44_RS22250	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
J4N44_RS22260	COG1288	antiporter activity
J4N44_RS22270	COG2814	Major facilitator Superfamily
J4N44_RS22280	COG3040	lipid binding
J4N44_RS22310	COG3469	chitinase activity
J4N44_RS22320	COG0419	ATPase involved in DNA repair
J4N44_RS22325	COG0420	3'-5' exonuclease activity
J4N44_RS22350	COG3209	COG3209 Rhs family protein
J4N44_RS22420	COG0631	protein serine/threonine phosphatase activity
J4N44_RS22455	COG2815	serine threonine protein kinase
J4N44_RS22455	COG0515	serine threonine protein kinase
J4N44_RS22480	COG0346	lactoylglutathione lyase activity
J4N44_RS22485	COG1902	pentaerythritol trinitrate reductase activity
J4N44_RS22495	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
J4N44_RS22495	COG2755	lipolytic protein G-D-S-L family
J4N44_RS22505	COG5642	Protein of unknown function (DUF2384)
J4N44_RS22520	COG1234	tRNA 3'-trailer cleavage
J4N44_RS22525	COG2067	long-chain fatty acid transport protein
J4N44_RS22605	COG1024	Enoyl-CoA hydratase
J4N44_RS22610	COG0628	permease
J4N44_RS22635	COG3038	cytochrome b561
J4N44_RS22645	COG0739	heme binding
J4N44_RS22695	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
J4N44_RS22695	COG2146	nitrite reductase [NAD(P)H] activity
J4N44_RS22700	COG1116	anion transmembrane transporter activity
J4N44_RS22705	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J4N44_RS22710	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
J4N44_RS22710	COG1116	anion transmembrane transporter activity
J4N44_RS22715	COG3707	response regulator
J4N44_RS22735	COG0243	molybdopterin cofactor binding
J4N44_RS22745	COG5001	Diguanylate cyclase
J4N44_RS22745	COG5002	protein histidine kinase activity
J4N44_RS22750	COG0814	amino acid
J4N44_RS22755	COG3706	GGDEF domain
J4N44_RS22775	COG1785	Belongs to the alkaline phosphatase family
J4N44_RS22790	COG0745	RESPONSE REGULATOR receiver
J4N44_RS22820	COG2847	Copper chaperone PCu(A)C
J4N44_RS22825	COG0443	Heat shock 70 kDa protein
J4N44_RS22895	COG0431	NADPH-dependent FMN reductase
J4N44_RS22895	COG1053	succinate dehydrogenase
J4N44_RS22895	COG3976	FMN-binding domain protein
J4N44_RS22900	COG5002	protein histidine kinase activity
J4N44_RS22920	COG0625	glutathione transferase activity
J4N44_RS22935	COG4160	amino acid transport
J4N44_RS22940	COG4215	(ABC) transporter
J4N44_RS22945	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J4N44_RS22950	COG1126	abc transporter atp-binding protein
J4N44_RS22985	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
J4N44_RS22995	COG1012	belongs to the aldehyde dehydrogenase family
J4N44_RS23005	COG0583	DNA-binding transcription factor activity
J4N44_RS23010	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
J4N44_RS23020	COG0513	Belongs to the DEAD box helicase family
J4N44_RS23025	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
J4N44_RS23040	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
J4N44_RS23055	COG2205	protein histidine kinase activity
J4N44_RS23060	COG0745	RESPONSE REGULATOR receiver
J4N44_RS23065	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
J4N44_RS23070	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
J4N44_RS23080	COG1119	ATPase activity
J4N44_RS23085	COG2200	EAL domain
J4N44_RS23105	COG0513	Belongs to the DEAD box helicase family
J4N44_RS23110	COG3447	MASE1 domain protein
J4N44_RS23110	COG5001	Diguanylate cyclase
J4N44_RS23110	COG5002	protein histidine kinase activity
J4N44_RS23115	COG0523	cobalamin synthesis protein
J4N44_RS23140	COG4206	TonB-dependent receptor
J4N44_RS23150	COG0789	Transcriptional regulator
J4N44_RS23155	COG4604	ABC transporter, ATP-binding protein
J4N44_RS23160	COG4605	iron ion homeostasis
J4N44_RS23165	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J4N44_RS23170	COG4607	ABC-type enterochelin transport system periplasmic component
J4N44_RS23185	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
J4N44_RS23200	COG1609	Transcriptional regulator
J4N44_RS23205	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J4N44_RS23210	COG1879	ABC-type sugar transport system periplasmic component
J4N44_RS23215	COG1172	Belongs to the binding-protein-dependent transport system permease family
J4N44_RS23220	COG1129	ABC transporter
J4N44_RS23230	COG5001	Diguanylate cyclase
J4N44_RS23235	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
J4N44_RS23245	COG1794	racemase activity, acting on amino acids and derivatives
J4N44_RS23310	COG2205	protein histidine kinase activity
J4N44_RS23310	COG0784	Response regulator, receiver
J4N44_RS23320	COG2205	protein histidine kinase activity
J4N44_RS23320	COG0784	Response regulator, receiver
J4N44_RS23340	COG0330	HflC and HflK could
J4N44_RS23375	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
J4N44_RS23385	COG2985	domain, Protein
J4N44_RS23410	COG2272	Belongs to the type-B carboxylesterase lipase family
J4N44_RS23415	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J4N44_RS23420	COG0729	surface antigen
J4N44_RS23435	COG4175	Glycine betaine
J4N44_RS23435	COG0517	IMP dehydrogenase activity
J4N44_RS23475	COG3706	GGDEF domain
J4N44_RS23490	COG0402	S-adenosylhomocysteine deaminase activity
J4N44_RS23500	COG0204	Acyl-transferase
J4N44_RS23530	COG2885	chlorophyll binding
J4N44_RS23570	COG0455	bacterial-type flagellum organization
J4N44_RS23580	COG4964	Belongs to the GSP D family
J4N44_RS23600	COG0583	DNA-binding transcription factor activity
J4N44_RS23605	COG1073	alpha beta
J4N44_RS23615	COG2425	protein containing a von Willebrand factor type A (vWA) domain
J4N44_RS23620	COG0714	Associated with various cellular activities
J4N44_RS23630	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
J4N44_RS23630	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
J4N44_RS23645	COG4989	oxidoreductase activity
J4N44_RS23670	COG1914	H( )-stimulated, divalent metal cation uptake system
J4N44_RS23685	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
J4N44_RS23700	COG2897	thiosulfate sulfurtransferase activity
J4N44_RS23725	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
J4N44_RS23730	COG0840	transmembrane signaling receptor activity
J4N44_RS23735	COG2814	Major facilitator Superfamily
J4N44_RS23740	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
J4N44_RS23755	COG1612	heme a metabolic process
J4N44_RS23775	COG1845	cytochrome c oxidase, subunit III
J4N44_RS23780	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
J4N44_RS23790	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
J4N44_RS23795	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
J4N44_RS23805	COG1280	lysine exporter protein (LysE YggA)
J4N44_RS23825	COG0179	Fumarylacetoacetate (FAA) hydrolase
J4N44_RS23840	COG0697	spore germination
J4N44_RS23855	COG2814	Major facilitator Superfamily
J4N44_RS23860	COG0583	DNA-binding transcription factor activity
J4N44_RS23865	COG5001	Diguanylate cyclase
J4N44_RS23870	COG0739	heme binding
J4N44_RS23890	COG3314	Sporulation integral membrane protein YlbJ
J4N44_RS23905	COG0814	amino acid
J4N44_RS23925	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
J4N44_RS23930	COG1072	(Pantothenic acid kinase))
J4N44_RS23940	COG1063	alcohol dehydrogenase
J4N44_RS23945	COG2213	PTS system mannitol-specific
J4N44_RS23950	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4N44_RS23955	COG2188	Transcriptional regulator
J4N44_RS23960	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4N44_RS23960	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4N44_RS23960	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4N44_RS23965	COG0383	alpha-mannosidase activity
J4N44_RS23970	COG1482	cell wall glycoprotein biosynthetic process
J4N44_RS23975	COG0747	negative chemotaxis
J4N44_RS23990	COG1733	regulation of RNA biosynthetic process
J4N44_RS24005	COG0798	PFAM Bile acid sodium symporter
J4N44_RS24020	COG1881	PFAM PEBP family protein
J4N44_RS24030	COG2249	NAD(P)H dehydrogenase (quinone) activity
J4N44_RS24045	COG0583	DNA-binding transcription factor activity
J4N44_RS24100	COG0366	Alpha amylase catalytic
J4N44_RS24110	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
J4N44_RS24115	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J4N44_RS24120	COG0784	Response regulator, receiver
J4N44_RS24120	COG0835	chemotaxis
J4N44_RS24130	COG0748	coenzyme F420 binding
J4N44_RS24135	COG3721	Heme iron utilization protein
J4N44_RS24145	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
J4N44_RS24150	COG0811	peptide transport
J4N44_RS24155	COG0848	biopolymer transport protein
J4N44_RS24165	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J4N44_RS24170	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
J4N44_RS24175	COG0840	transmembrane signaling receptor activity
J4N44_RS24185	COG1131	(ABC) transporter
J4N44_RS24190	COG0842	Transport permease protein
J4N44_RS24195	COG0251	oxidation-reduction process
J4N44_RS24210	COG0800	Aldolase
J4N44_RS24215	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J4N44_RS24220	COG4145	pantothenate transmembrane transporter activity
J4N44_RS24230	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
J4N44_RS24255	COG3383	formate dehydrogenase (NAD+) activity
J4N44_RS24275	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J4N44_RS24300	COG0604	alcohol dehydrogenase
J4N44_RS24300	COG3321	synthase
J4N44_RS24300	COG1028	Short-chain dehydrogenase reductase Sdr
J4N44_RS24315	COG0456	acetyltransferase
J4N44_RS24335	COG0612	Peptidase, M16
J4N44_RS24340	COG4178	(ABC) transporter
J4N44_RS24345	COG4771	TonB-dependent receptor
J4N44_RS24355	COG0811	peptide transport
J4N44_RS24360	COG0811	peptide transport
J4N44_RS24365	COG0848	biopolymer transport protein
J4N44_RS24390	COG1858	cytochrome C peroxidase
J4N44_RS24400	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J4N44_RS24410	COG1505	serine-type exopeptidase activity
J4N44_RS24415	COG0488	(ABC) transporter
J4N44_RS24420	COG1720	tRNA m6t6A37 methyltransferase activity
J4N44_RS24440	COG0589	response to stress
J4N44_RS24465	COG1175	transmembrane transport
J4N44_RS24470	COG0395	ABC-type sugar transport system, permease component
J4N44_RS24475	COG3842	ATPase activity
J4N44_RS24505	COG0523	cobalamin synthesis protein
J4N44_RS24515	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
J4N44_RS24525	COG4667	esterase of the alpha-beta hydrolase superfamily
J4N44_RS24530	COG1741	Belongs to the pirin family
J4N44_RS24535	COG1278	Cold shock
J4N44_RS24550	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
J4N44_RS24580	COG2226	methyltransferase
J4N44_RS24590	COG3706	GGDEF domain
J4N44_RS24595	COG1686	Belongs to the peptidase S11 family
J4N44_RS24600	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
J4N44_RS24605	COG2249	NAD(P)H dehydrogenase (quinone) activity
J4N44_RS24610	COG0583	DNA-binding transcription factor activity
J4N44_RS24615	COG0625	glutathione transferase activity
J4N44_RS24625	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
J4N44_RS24650	COG0681	Belongs to the peptidase S26 family
J4N44_RS24670	COG1028	Short-chain dehydrogenase reductase Sdr
J4N44_RS24695	COG3746	phosphate-selective porin O and P
J4N44_RS24710	COG1028	Short-chain dehydrogenase reductase Sdr
J4N44_RS24720	COG1301	dicarboxylic acid transport
J4N44_RS24725	COG1252	NADH dehydrogenase
J4N44_RS24735	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
J4N44_RS24740	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
J4N44_RS24765	COG1028	Short-chain dehydrogenase reductase Sdr
J4N44_RS24770	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
J4N44_RS24780	COG0573	inorganic phosphate transmembrane transporter activity
J4N44_RS24790	COG4191	Histidine kinase
J4N44_RS24800	COG0110	maltose O-acetyltransferase activity
J4N44_RS24835	COG0840	transmembrane signaling receptor activity
J4N44_RS24840	COG0714	Associated with various cellular activities
J4N44_RS24860	COG2304	oxidoreductase activity
J4N44_RS24875	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
J4N44_RS24880	COG0581	inorganic phosphate transmembrane transporter activity
J4N44_RS24885	COG0573	inorganic phosphate transmembrane transporter activity
J4N44_RS24895	COG0840	transmembrane signaling receptor activity
J4N44_RS24905	COG0513	Belongs to the DEAD box helicase family
J4N44_RS24915	COG1388	LysM domain
J4N44_RS24915	COG1376	ErfK ybiS ycfS ynhG family protein
J4N44_RS24920	COG0415	Belongs to the DNA photolyase family
J4N44_RS24925	COG0789	Transcriptional regulator
J4N44_RS24930	COG3272	Protein of unknown function (DUF1722)
J4N44_RS24935	COG0813	purine-nucleoside phosphorylase activity
J4N44_RS24965	COG1566	PFAM secretion protein HlyD family protein
J4N44_RS24975	COG1122	ATPase activity
J4N44_RS24995	COG0348	domain, Protein
J4N44_RS25000	COG0437	4 iron, 4 sulfur cluster binding
J4N44_RS25005	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J4N44_RS25035	COG1067	ATP-dependent peptidase activity
J4N44_RS25045	COG4172	Belongs to the ABC transporter superfamily
J4N44_RS25050	COG1505	serine-type exopeptidase activity
J4N44_RS25055	COG0583	DNA-binding transcription factor activity
J4N44_RS25060	COG1620	l-lactate permease
J4N44_RS25065	COG1304	FMN binding
J4N44_RS25075	COG0668	transmembrane transport
J4N44_RS25090	COG4948	Mandelate Racemase Muconate Lactonizing
J4N44_RS25095	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
J4N44_RS25115	COG1342	Belongs to the UPF0251 family
J4N44_RS25125	COG4176	ABC-type proline glycine betaine transport system permease component
J4N44_RS25130	COG3448	diguanylate cyclase activity
J4N44_RS25130	COG4175	Glycine betaine
J4N44_RS25155	COG0583	DNA-binding transcription factor activity
J4N44_RS25200	COG1335	isochorismatase
J4N44_RS25215	COG0753	catalase activity
J4N44_RS25240	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
J4N44_RS25245	COG1263	PTS System
J4N44_RS25245	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J4N44_RS25250	COG1609	Transcriptional regulator
J4N44_RS25255	COG1349	DNA-binding transcription factor activity
J4N44_RS25260	COG0346	lactoylglutathione lyase activity
J4N44_RS25265	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J4N44_RS25265	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J4N44_RS25275	COG1263	PTS System
J4N44_RS25275	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J4N44_RS25280	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
J4N44_RS25285	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
J4N44_RS25290	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
J4N44_RS25300	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J4N44_RS25315	COG0561	phosphatase activity
J4N44_RS25330	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4N44_RS25335	COG3537	Alpha-1,2-mannosidase
J4N44_RS25340	COG3537	Alpha-1,2-mannosidase
J4N44_RS25350	COG3537	Alpha-1,2-mannosidase
J4N44_RS25355	COG3537	Alpha-1,2-mannosidase
J4N44_RS25370	COG1280	lysine exporter protein (LysE YggA)
J4N44_RS25375	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J4N44_RS25390	COG3226	Transcriptional regulator
J4N44_RS25395	COG0583	DNA-binding transcription factor activity
J4N44_RS25410	COG0488	(ABC) transporter
J4N44_RS25415	COG0435	Glutathione S-transferase
J4N44_RS25420	COG0431	NADPH-dependent FMN reductase
J4N44_RS25425	COG0583	DNA-binding transcription factor activity
J4N44_RS25430	COG4628	conserved protein (DUF2132)
J4N44_RS25435	COG0488	(ABC) transporter
J4N44_RS25450	COG0346	lactoylglutathione lyase activity
J4N44_RS25455	COG0384	phenazine biosynthesis protein PhzF
J4N44_RS25470	COG3220	belongs to the UPF0276 family
J4N44_RS25485	COG1271	oxidase subunit
J4N44_RS25490	COG1294	oxidase, subunit
J4N44_RS25530	COG1917	Cupin 2, conserved barrel domain protein
J4N44_RS25530	COG2207	Transcriptional regulator
J4N44_RS25535	COG2207	Transcriptional regulator
J4N44_RS25545	COG1882	Formate acetyltransferase
J4N44_RS25550	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
J4N44_RS25555	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
J4N44_RS25570	COG2205	protein histidine kinase activity
J4N44_RS25575	COG0745	RESPONSE REGULATOR receiver
J4N44_RS25585	COG0454	-acetyltransferase
J4N44_RS25595	COG2814	Major facilitator Superfamily
J4N44_RS25610	COG0583	DNA-binding transcription factor activity
J4N44_RS25615	COG2988	succinylglutamate desuccinylase activity
J4N44_RS25655	COG0628	permease
J4N44_RS25660	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
J4N44_RS25675	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
J4N44_RS25685	COG4628	conserved protein (DUF2132)
J4N44_RS25690	COG0583	DNA-binding transcription factor activity
J4N44_RS25715	COG1686	Belongs to the peptidase S11 family
J4N44_RS25730	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
J4N44_RS25750	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
J4N44_RS25755	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
J4N44_RS25770	COG0415	Belongs to the DNA photolyase family
J4N44_RS25775	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
J4N44_RS25785	COG4667	esterase of the alpha-beta hydrolase superfamily
J4N44_RS25790	COG2095	MarC family integral membrane protein
J4N44_RS25800	COG1596	polysaccharide export
J4N44_RS25825	COG0583	DNA-binding transcription factor activity
J4N44_RS25855	COG1301	dicarboxylic acid transport
J4N44_RS25870	COG3339	Conserved Protein
J4N44_RS25875	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
J4N44_RS25880	COG0700	Nucleoside recognition
J4N44_RS25885	COG3366	ferrous iron transmembrane transporter activity
J4N44_RS25900	COG0366	Alpha amylase catalytic
J4N44_RS25905	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J4N44_RS25910	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
J4N44_RS25915	COG1640	4-alpha-glucanotransferase
J4N44_RS25920	COG0058	SHG alpha-glucan phosphorylase activity
J4N44_RS25940	COG1999	signal sequence binding
J4N44_RS25950	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J4N44_RS25950	COG1263	PTS System
J4N44_RS25955	COG1162	GTPase activity
J4N44_RS25960	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
J4N44_RS25965	COG0673	inositol 2-dehydrogenase activity
J4N44_RS25990	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J4N44_RS25995	COG0673	inositol 2-dehydrogenase activity
J4N44_RS26000	COG3962	Belongs to the TPP enzyme family
J4N44_RS26010	COG2814	Major facilitator Superfamily
J4N44_RS26010	COG0477	Major facilitator Superfamily
J4N44_RS26015	COG0583	DNA-binding transcription factor activity
J4N44_RS26030	COG0183	Belongs to the thiolase family
J4N44_RS26060	COG0531	amino acid
J4N44_RS26065	COG1982	Orn Lys Arg decarboxylase major
J4N44_RS26085	COG1929	Belongs to the glycerate kinase type-1 family
J4N44_RS26090	COG3835	regulator
J4N44_RS26100	COG1228	amidohydrolase
J4N44_RS26125	COG0546	phosphoglycolate phosphatase activity
J4N44_RS26160	COG1132	(ABC) transporter
J4N44_RS26165	COG1132	(ABC) transporter
J4N44_RS26170	COG4771	TonB-dependent receptor
J4N44_RS26210	COG3408	Glycogen debranching enzyme
J4N44_RS26210	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
J4N44_RS26230	COG2814	Major facilitator Superfamily
J4N44_RS26245	COG2358	TRAP transporter, solute receptor (TAXI family
J4N44_RS26250	COG3047	cAMP biosynthetic process
J4N44_RS26255	COG1357	PFAM Pentapeptide repeats (8 copies)
J4N44_RS26280	COG2076	Multidrug Resistance protein
J4N44_RS26315	COG0583	DNA-binding transcription factor activity
J4N44_RS26330	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
J4N44_RS26345	COG3152	Membrane
J4N44_RS26355	COG2199	diguanylate cyclase activity
J4N44_RS26365	COG0561	phosphatase activity
J4N44_RS26375	COG0564	pseudouridine synthase activity
J4N44_RS26380	COG0534	Mate efflux family protein
J4N44_RS26385	COG1609	Transcriptional regulator
J4N44_RS26390	COG3842	ATPase activity
J4N44_RS26395	COG2723	6-phospho-beta-galactosidase activity
J4N44_RS26400	COG0395	ABC-type sugar transport system, permease component
J4N44_RS26415	COG1609	Transcriptional regulator
J4N44_RS26420	COG4580	involved in the transport of maltose and maltodextrins
J4N44_RS26485	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
J4N44_RS26495	COG0826	peptidase U32
J4N44_RS26515	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4N44_RS26520	COG3716	PTS system mannose fructose sorbose family IID component
J4N44_RS26530	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J4N44_RS26535	COG2222	sugar isomerase
J4N44_RS26545	COG1349	DNA-binding transcription factor activity
J4N44_RS26550	COG1349	DNA-binding transcription factor activity
J4N44_RS26560	COG1136	(ABC) transporter
J4N44_RS26565	COG0577	efflux transmembrane transporter activity
J4N44_RS26595	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
J4N44_RS26600	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
J4N44_RS26610	COG2259	Doxx family
J4N44_RS26645	COG3623	hexulose-6-phosphate isomerase
J4N44_RS26650	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
J4N44_RS26655	COG0561	phosphatase activity
J4N44_RS26685	COG0786	glutamate:sodium symporter activity
J4N44_RS26690	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J4N44_RS26695	COG1131	(ABC) transporter
J4N44_RS26710	COG0786	glutamate:sodium symporter activity
J4N44_RS26735	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
J4N44_RS26740	COG3279	Response regulator of the LytR AlgR family
J4N44_RS26745	COG3275	phosphorelay sensor kinase activity
J4N44_RS26765	COG1136	(ABC) transporter
J4N44_RS26775	COG0583	DNA-binding transcription factor activity
J4N44_RS26780	COG1566	PFAM secretion protein HlyD family protein
J4N44_RS26790	COG0772	Belongs to the SEDS family
J4N44_RS26815	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
J4N44_RS26815	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
J4N44_RS26825	COG0444	Belongs to the ABC transporter superfamily
J4N44_RS26830	COG4608	Belongs to the ABC transporter superfamily
J4N44_RS27345	COG2003	Belongs to the UPF0758 family
J4N44_RS27510	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
J4N44_RS27610	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
J4N44_RS27830	COG1459	type II secretion system
J4N44_RS27925	COG5001	Diguanylate cyclase
J4N44_RS28005	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
J4N44_RS28040	COG1061	Type III restriction enzyme res subunit
J4N44_RS28115	COG0545	Peptidyl-prolyl cis-trans isomerase