locus-tag	class	description
GFB47_RS00010	COG0592	DNA-directed DNA polymerase activity
GFB47_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GFB47_RS00020	COG0187	DNA topoisomerase II activity
GFB47_RS00025	COG3069	C4-dicarboxylate transmembrane transporter activity
GFB47_RS00035	COG0071	Belongs to the small heat shock protein (HSP20) family
GFB47_RS00040	COG0753	catalase activity
GFB47_RS00050	COG3977	Valine--pyruvate aminotransferase
GFB47_RS00055	COG0751	glycine-tRNA ligase activity
GFB47_RS00060	COG0752	glycyl-tRNA synthetase alpha subunit
GFB47_RS00065	COG1971	Probably functions as a manganese efflux pump
GFB47_RS00075	COG0425	Belongs to the sulfur carrier protein TusA family
GFB47_RS00080	COG1965	Belongs to the frataxin family
GFB47_RS00090	COG0019	diaminopimelate decarboxylase activity
GFB47_RS00095	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GFB47_RS00105	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
GFB47_RS00110	COG1011	Hydrolase
GFB47_RS00115	COG3148	PFAM DTW domain containing protein
GFB47_RS00130	COG0561	phosphatase activity
GFB47_RS00135	COG2267	carboxylic ester hydrolase activity
GFB47_RS00160	COG2095	MarC family integral membrane protein
GFB47_RS00170	COG0742	ribosomal rna small subunit methyltransferase
GFB47_RS00175	COG0552	protein localization to endoplasmic reticulum
GFB47_RS00180	COG2884	Cell division ATP-binding protein ftsE
GFB47_RS00185	COG2177	Part of the ABC transporter FtsEX involved in
GFB47_RS00190	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GFB47_RS00195	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GFB47_RS00205	COG3161	chorismate lyase activity
GFB47_RS00210	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
GFB47_RS00215	COG2937	Belongs to the GPAT DAPAT family
GFB47_RS00220	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GFB47_RS00225	COG0534	Mate efflux family protein
GFB47_RS00230	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GFB47_RS00235	COG1309	transcriptional regulator
GFB47_RS00240	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GFB47_RS00245	COG4206	TonB-dependent receptor
GFB47_RS00285	COG0038	chloride channel
GFB47_RS00290	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
GFB47_RS00295	COG0352	thiamine-phosphate diphosphorylase activity
GFB47_RS00300	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GFB47_RS00305	COG2104	thiamine diphosphate biosynthetic process
GFB47_RS00310	COG2022	thiamine diphosphate biosynthetic process
GFB47_RS00315	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GFB47_RS00320	COG0006	proline dipeptidase activity
GFB47_RS00330	COG0697	spore germination
GFB47_RS00335	COG1322	Protein conserved in bacteria
GFB47_RS00340	COG2226	methyltransferase
GFB47_RS00355	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GFB47_RS00360	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GFB47_RS00365	COG0805	protein transport
GFB47_RS00370	COG0084	hydrolase, TatD family'
GFB47_RS00380	COG0248	Ppx GppA phosphatase
GFB47_RS00385	COG0513	Belongs to the DEAD box helicase family
GFB47_RS00390	COG3118	belongs to the thioredoxin family
GFB47_RS00405	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GFB47_RS00455	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GFB47_RS00465	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GFB47_RS00475	COG1072	(Pantothenic acid kinase))
GFB47_RS00500	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GFB47_RS00505	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GFB47_RS00510	COG0250	Participates in transcription elongation, termination and antitermination
GFB47_RS00520	COG0081	regulation of translation
GFB47_RS00525	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GFB47_RS00535	COG0085	RNA polymerase activity
GFB47_RS00545	COG2076	Multidrug Resistance protein
GFB47_RS00550	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
GFB47_RS00560	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
GFB47_RS00570	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GFB47_RS00585	COG1573	uracil-dna glycosylase
GFB47_RS00595	COG3068	Protein conserved in bacteria
GFB47_RS00610	COG0151	Belongs to the GarS family
GFB47_RS00625	COG1609	Transcriptional regulator
GFB47_RS00630	COG1263	PTS System
GFB47_RS00630	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GFB47_RS00635	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GFB47_RS00645	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
GFB47_RS00650	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GFB47_RS00655	COG2264	protein methyltransferase activity
GFB47_RS00660	COG4145	pantothenate transmembrane transporter activity
GFB47_RS00665	COG3924	membrane
GFB47_RS00675	COG0439	Biotin carboxylase
GFB47_RS00680	COG0511	ligase activity, forming carbon-carbon bonds
GFB47_RS00685	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GFB47_RS00690	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GFB47_RS00705	COG0577	efflux transmembrane transporter activity
GFB47_RS00705	COG1136	(ABC) transporter
GFB47_RS00710	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GFB47_RS00720	COG2205	protein histidine kinase activity
GFB47_RS00720	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GFB47_RS00730	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GFB47_RS00745	COG4232	protein-disulfide reductase activity
GFB47_RS00770	COG1522	sequence-specific DNA binding
GFB47_RS00775	COG5002	protein histidine kinase activity
GFB47_RS00775	COG5001	Diguanylate cyclase
GFB47_RS00780	COG0742	ribosomal rna small subunit methyltransferase
GFB47_RS00795	COG4566	intracellular signal transduction
GFB47_RS00810	COG0589	response to stress
GFB47_RS00815	COG1528	Iron-storage protein
GFB47_RS00825	COG2081	HI0933 family
GFB47_RS00860	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GFB47_RS00875	COG0300	oxidoreductase activity
GFB47_RS00885	COG0415	Belongs to the DNA photolyase family
GFB47_RS00900	COG1595	DNA-templated transcription, initiation
GFB47_RS00905	COG0471	metal ion transport
GFB47_RS00910	COG4221	oxidoreductase activity
GFB47_RS00915	COG0583	DNA-binding transcription factor activity
GFB47_RS00925	COG0210	DNA helicase
GFB47_RS00935	COG0205	6-phosphofructokinase activity
GFB47_RS00955	COG1494	fructose-1,6-bisphosphatase
GFB47_RS00965	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GFB47_RS00970	COG1575	Belongs to the MenA family. Type 1 subfamily
GFB47_RS00980	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GFB47_RS00990	COG1609	Transcriptional regulator
GFB47_RS00995	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GFB47_RS01000	COG0254	rRNA binding
GFB47_RS01005	COG0281	malic enzyme
GFB47_RS01010	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
GFB47_RS01015	COG0626	cystathionine gamma-synthase activity
GFB47_RS01020	COG0527	aspartate kinase activity
GFB47_RS01020	COG0460	homoserine dehydrogenase
GFB47_RS01025	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GFB47_RS01045	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
GFB47_RS01050	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GFB47_RS01055	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GFB47_RS01065	COG0137	argininosuccinate synthase activity
GFB47_RS01070	COG0165	Argininosuccinate lyase
GFB47_RS01070	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GFB47_RS01080	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GFB47_RS01085	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GFB47_RS01085	COG0678	peroxiredoxin activity
GFB47_RS01095	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
GFB47_RS01125	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GFB47_RS01130	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GFB47_RS01140	COG0338	D12 class N6 adenine-specific DNA methyltransferase
GFB47_RS01145	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GFB47_RS01150	COG1560	Kdo2-lipid A biosynthetic process
GFB47_RS01155	COG1309	transcriptional regulator
GFB47_RS01160	COG0756	dUTP diphosphatase activity
GFB47_RS01165	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GFB47_RS01170	COG2003	Belongs to the UPF0758 family
GFB47_RS01175	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GFB47_RS01180	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GFB47_RS01185	COG2233	PERMEase
GFB47_RS01205	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GFB47_RS01210	COG2183	response to ionizing radiation
GFB47_RS01220	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GFB47_RS01240	COG0463	Glycosyl transferase, family 2
GFB47_RS01245	COG0859	PFAM glycosyl transferase family 9
GFB47_RS01250	COG3642	lipopolysaccharide core region biosynthetic process
GFB47_RS01260	COG1442	glycosyl transferase family 8
GFB47_RS01265	COG0438	transferase activity, transferring glycosyl groups
GFB47_RS01270	COG1519	Transferase
GFB47_RS01290	COG0110	maltose O-acetyltransferase activity
GFB47_RS01295	COG0859	PFAM glycosyl transferase family 9
GFB47_RS01300	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GFB47_RS01320	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
GFB47_RS01360	COG1215	transferase activity, transferring glycosyl groups
GFB47_RS01370	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GFB47_RS01385	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
GFB47_RS01400	COG1045	serine acetyltransferase
GFB47_RS01405	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GFB47_RS01415	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GFB47_RS01430	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GFB47_RS01435	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GFB47_RS01440	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GFB47_RS01445	COG4942	peptidase
GFB47_RS01450	COG0534	Mate efflux family protein
GFB47_RS01465	COG1119	ATPase activity
GFB47_RS01475	COG0604	alcohol dehydrogenase
GFB47_RS01485	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
GFB47_RS01490	COG0237	dephospho-CoA kinase activity
GFB47_RS01500	COG1459	type II secretion system
GFB47_RS01505	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GFB47_RS01520	COG2186	Transcriptional regulator
GFB47_RS01525	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
GFB47_RS01530	COG0508	dehydrogenase complex catalyzes the overall conversion of
GFB47_RS01535	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GFB47_RS01550	COG0288	reversible hydration of carbon dioxide
GFB47_RS01555	COG1131	(ABC) transporter
GFB47_RS01560	COG0842	Transport permease protein
GFB47_RS01570	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GFB47_RS01575	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GFB47_RS01580	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GFB47_RS01590	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GFB47_RS01595	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GFB47_RS01605	COG1643	Atp-dependent helicase
GFB47_RS01610	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GFB47_RS01645	COG5295	Hep Hag repeat protein
GFB47_RS01645	COG1293	RNA-binding protein homologous to eukaryotic snRNP
GFB47_RS01665	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
GFB47_RS01675	COG3107	peptidoglycan biosynthetic process
GFB47_RS01680	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GFB47_RS01690	COG0275	rRNA processing
GFB47_RS01695	COG3116	cell division
GFB47_RS01700	COG0768	penicillin binding
GFB47_RS01710	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GFB47_RS01715	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GFB47_RS01720	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GFB47_RS01725	COG0772	Belongs to the SEDS family
GFB47_RS01730	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GFB47_RS01735	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GFB47_RS01740	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GFB47_RS01745	COG0849	cell division
GFB47_RS01750	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GFB47_RS01755	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
GFB47_RS01770	COG0494	nUDIX hydrolase
GFB47_RS01775	COG4991	sh3 domain protein
GFB47_RS01780	COG0306	phosphate transporter
GFB47_RS01785	COG1392	Phosphate transport regulator
GFB47_RS01790	COG3025	triphosphatase activity
GFB47_RS01795	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GFB47_RS01805	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
GFB47_RS01805	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
GFB47_RS01810	COG1538	Outer membrane efflux protein
GFB47_RS01815	COG0494	nUDIX hydrolase
GFB47_RS01820	COG3151	Protein conserved in bacteria
GFB47_RS01830	COG3150	esterase
GFB47_RS01855	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GFB47_RS01860	COG3105	Protein conserved in bacteria
GFB47_RS01865	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
GFB47_RS01875	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GFB47_RS01880	COG0723	plastoquinol--plastocyanin reductase activity
GFB47_RS01885	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GFB47_RS01890	COG2857	Cytochrome c1
GFB47_RS01895	COG0625	glutathione transferase activity
GFB47_RS01900	COG2969	positive regulation of protein catabolic process
GFB47_RS01905	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
GFB47_RS01915	COG0646	methionine synthase
GFB47_RS01915	COG1410	methionine synthase
GFB47_RS01920	COG0527	aspartate kinase activity
GFB47_RS01925	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GFB47_RS01935	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GFB47_RS01945	COG2197	response regulator
GFB47_RS01950	COG0629	single-stranded DNA binding
GFB47_RS01955	COG2200	EAL domain
GFB47_RS01955	COG2199	diguanylate cyclase activity
GFB47_RS01975	COG1077	Cell shape determining protein MreB Mrl
GFB47_RS01980	COG1792	Involved in formation and maintenance of cell shape
GFB47_RS01985	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
GFB47_RS01990	COG0424	maF-like protein
GFB47_RS02000	COG3164	Protein of unknown function
GFB47_RS02005	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GFB47_RS02010	COG0312	modulator of DNA gyrase
GFB47_RS02015	COG3028	Belongs to the UPF0307 family
GFB47_RS02020	COG0312	modulator of DNA gyrase
GFB47_RS02025	COG2239	Acts as a magnesium transporter
GFB47_RS02030	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GFB47_RS02035	COG1660	Displays ATPase and GTPase activities
GFB47_RS02040	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GFB47_RS02045	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GFB47_RS02055	COG1137	ATPase activity
GFB47_RS02070	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
GFB47_RS02075	COG0517	IMP dehydrogenase activity
GFB47_RS02075	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GFB47_RS02085	COG1127	ABC transporter
GFB47_RS02090	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GFB47_RS02095	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GFB47_RS02100	COG2854	intermembrane phospholipid transfer
GFB47_RS02110	COG5007	Belongs to the BolA IbaG family
GFB47_RS02115	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GFB47_RS02120	COG0204	Acyl-transferase
GFB47_RS02125	COG1846	Transcriptional regulator
GFB47_RS02130	COG1566	PFAM secretion protein HlyD family protein
GFB47_RS02135	COG2814	Major facilitator Superfamily
GFB47_RS02140	COG0251	oxidation-reduction process
GFB47_RS02150	COG0540	Belongs to the ATCase OTCase family
GFB47_RS02155	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GFB47_RS02180	COG0525	valine-tRNA ligase activity
GFB47_RS02185	COG2927	DNA polymerase III (CHI subunit)
GFB47_RS02195	COG0795	lipopolysaccharide-transporting ATPase activity
GFB47_RS02200	COG0795	lipopolysaccharide-transporting ATPase activity
GFB47_RS02215	COG0463	Glycosyl transferase, family 2
GFB47_RS02225	COG1012	belongs to the aldehyde dehydrogenase family
GFB47_RS02285	COG0741	lytic transglycosylase activity
GFB47_RS02290	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
GFB47_RS02295	COG1194	a g-specific adenine glycosylase
GFB47_RS02305	COG2066	Belongs to the glutaminase family
GFB47_RS02310	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GFB47_RS02315	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GFB47_RS02325	COG1872	DUF167
GFB47_RS02330	COG0762	integral membrane protein
GFB47_RS02335	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GFB47_RS02340	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GFB47_RS02355	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GFB47_RS02360	COG1678	Uncharacterized ACR, COG1678
GFB47_RS02365	COG0189	ligase activity
GFB47_RS02370	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GFB47_RS02380	COG3091	SprT-like family
GFB47_RS02395	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GFB47_RS02400	COG3104	oligopeptide transport
GFB47_RS02405	COG2855	membrane
GFB47_RS02410	COG0589	response to stress
GFB47_RS02420	COG0126	phosphoglycerate kinase activity
GFB47_RS02425	COG0191	fructose-bisphosphate aldolase activity
GFB47_RS02430	COG0668	transmembrane transport
GFB47_RS02440	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GFB47_RS02450	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GFB47_RS02470	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GFB47_RS02475	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GFB47_RS02485	COG0354	folic acid binding
GFB47_RS02490	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
GFB47_RS02500	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GFB47_RS02505	COG1595	DNA-templated transcription, initiation
GFB47_RS02520	COG3086	response to oxidative stress
GFB47_RS02525	COG0481	GTPase activity
GFB47_RS02540	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GFB47_RS02545	COG1381	Involved in DNA repair and RecF pathway recombination
GFB47_RS02550	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
GFB47_RS02555	COG0736	holo-[acyl-carrier-protein] synthase activity
GFB47_RS02570	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GFB47_RS02575	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GFB47_RS02580	COG3956	TIGRFAM MazG family protein
GFB47_RS02590	COG0148	phosphopyruvate hydratase activity
GFB47_RS02600	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
GFB47_RS02605	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GFB47_RS02605	COG0047	phosphoribosylformylglycinamidine synthase activity
GFB47_RS02615	COG0514	ATP-dependent DNA helicase (RecQ)
GFB47_RS02655	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GFB47_RS02660	COG0442	prolyl-tRNA aminoacylation
GFB47_RS02665	COG1720	tRNA m6t6A37 methyltransferase activity
GFB47_RS02670	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
GFB47_RS02680	COG1464	Belongs to the NlpA lipoprotein family
GFB47_RS02685	COG2011	ABC-type metal ion transport system permease component
GFB47_RS02690	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GFB47_RS02695	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GFB47_RS02700	COG0814	amino acid
GFB47_RS02705	COG4174	ABC transporter (Permease)
GFB47_RS02710	COG4239	(ABC) transporter, permease
GFB47_RS02725	COG4608	Belongs to the ABC transporter superfamily
GFB47_RS02755	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GFB47_RS02760	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GFB47_RS02760	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GFB47_RS02780	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GFB47_RS02790	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GFB47_RS02800	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GFB47_RS02805	COG0142	geranyltranstransferase activity
GFB47_RS02810	COG1722	exodeoxyribonuclease VII activity
GFB47_RS02815	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GFB47_RS02815	COG0301	tRNA thio-modification
GFB47_RS02830	COG2363	Small membrane protein
GFB47_RS02835	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
GFB47_RS02840	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GFB47_RS02845	COG1611	Belongs to the LOG family
GFB47_RS02865	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
GFB47_RS02870	COG1671	Belongs to the UPF0178 family
GFB47_RS02890	COG3098	single-species biofilm formation
GFB47_RS02895	COG0564	pseudouridine synthase activity
GFB47_RS02905	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
GFB47_RS02910	COG0024	Methionine aminopeptidase
GFB47_RS02930	COG0233	cytoplasmic translational termination
GFB47_RS02935	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GFB47_RS02940	COG0575	Belongs to the CDS family
GFB47_RS02945	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GFB47_RS02950	COG0750	zinc metalloprotease
GFB47_RS02960	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
GFB47_RS02965	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GFB47_RS02970	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GFB47_RS02975	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GFB47_RS02985	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GFB47_RS02990	COG0587	DNA-directed DNA polymerase activity
GFB47_RS02995	COG0825	malonyl-CoA metabolic process
GFB47_RS03000	COG0037	tRNA processing
GFB47_RS03005	COG0347	Belongs to the P(II) protein family
GFB47_RS03015	COG1388	LysM domain
GFB47_RS03015	COG0741	lytic transglycosylase activity
GFB47_RS03020	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GFB47_RS03025	COG2226	methyltransferase
GFB47_RS03030	COG2166	iron-sulfur cluster assembly
GFB47_RS03040	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GFB47_RS03045	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GFB47_RS03060	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GFB47_RS03070	COG2813	Specifically methylates the guanine in position
GFB47_RS03075	COG0271	Belongs to the BolA IbaG family
GFB47_RS03080	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GFB47_RS03085	COG1805	sodium ion transport
GFB47_RS03090	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GFB47_RS03100	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GFB47_RS03105	COG2871	sodium ion transport
GFB47_RS03110	COG1477	protein flavinylation
GFB47_RS03115	COG2991	Protein conserved in bacteria
GFB47_RS03120	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GFB47_RS03125	COG2195	Cleaves the N-terminal amino acid of tripeptides
GFB47_RS03130	COG2252	PERMEase
GFB47_RS03135	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
GFB47_RS03145	COG1073	alpha beta
GFB47_RS03155	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GFB47_RS03160	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GFB47_RS03165	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GFB47_RS03170	COG0321	lipoyl(octanoyl) transferase activity
GFB47_RS03180	COG1686	Belongs to the peptidase S11 family
GFB47_RS03185	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GFB47_RS03190	COG0772	Belongs to the SEDS family
GFB47_RS03195	COG0768	penicillin binding
GFB47_RS03200	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GFB47_RS03205	COG0799	negative regulation of ribosome biogenesis
GFB47_RS03210	COG1466	dna polymerase III delta subunit
GFB47_RS03215	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
GFB47_RS03220	COG0495	leucyl-tRNA aminoacylation
GFB47_RS03225	COG2888	peptidyl-tyrosine sulfation
GFB47_RS03230	COG3069	C4-dicarboxylate transmembrane transporter activity
GFB47_RS03240	COG1368	sulfuric ester hydrolase activity
GFB47_RS03245	COG0815	Transfers the fatty acyl group on membrane lipoproteins
GFB47_RS03250	COG4535	Mg2 and Co2 transporter CorC
GFB47_RS03260	COG1702	phosphate starvation-inducible protein PhoH
GFB47_RS03265	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GFB47_RS03270	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GFB47_RS03275	COG2706	6-phosphogluconolactonase activity
GFB47_RS03340	COG0193	aminoacyl-tRNA hydrolase activity
GFB47_RS03345	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GFB47_RS03350	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GFB47_RS03355	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
GFB47_RS03360	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
GFB47_RS03365	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GFB47_RS03370	COG2890	protein-(glutamine-N5) methyltransferase activity
GFB47_RS03375	COG3094	Invasion gene expression up-regulator, SirB
GFB47_RS03380	COG2912	Transglutaminase-like superfamily
GFB47_RS03385	COG2877	3-deoxy-8-phosphooctulonate synthase activity
GFB47_RS03390	COG0737	Belongs to the 5'-nucleotidase family
GFB47_RS03395	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GFB47_RS03400	COG1187	pseudouridine synthase activity
GFB47_RS03410	COG2015	COG2015, Alkyl sulfatase and related hydrolases
GFB47_RS03415	COG2840	Smr protein MutS2
GFB47_RS03435	COG2608	mercury ion transmembrane transporter activity
GFB47_RS03435	COG2217	Heavy metal translocating P-type atpase
GFB47_RS03455	COG0811	peptide transport
GFB47_RS03460	COG0811	peptide transport
GFB47_RS03465	COG0848	biopolymer transport protein
GFB47_RS03485	COG0443	Heat shock 70 kDa protein
GFB47_RS03500	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
GFB47_RS03510	COG1120	ATPase activity
GFB47_RS03525	COG2199	diguanylate cyclase activity
GFB47_RS03540	COG4133	protoheme IX ABC transporter activity
GFB47_RS03545	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GFB47_RS03550	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GFB47_RS03560	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
GFB47_RS03565	COG1138	Cytochrome C-type biogenesis protein
GFB47_RS03570	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GFB47_RS03575	COG3088	subunit of a heme lyase
GFB47_RS03575	COG4235	cytochrome complex assembly
GFB47_RS03590	COG2067	long-chain fatty acid transport protein
GFB47_RS03605	COG0183	Belongs to the thiolase family
GFB47_RS03610	COG1250	3-hydroxyacyl-CoA dehydrogenase
GFB47_RS03610	COG1024	Enoyl-CoA hydratase
GFB47_RS03615	COG3706	GGDEF domain
GFB47_RS03625	COG3093	addiction module antidote protein HigA
GFB47_RS03630	COG1025	Belongs to the peptidase M16 family
GFB47_RS03635	COG2062	phosphohistidine phosphatase, SixA
GFB47_RS03645	COG2890	protein-(glutamine-N5) methyltransferase activity
GFB47_RS03650	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GFB47_RS03655	COG3101	peptidyl-lysine hydroxylation
GFB47_RS03670	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
GFB47_RS03670	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GFB47_RS03675	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GFB47_RS03680	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GFB47_RS03685	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GFB47_RS03695	COG0101	tRNA pseudouridine synthase activity
GFB47_RS03700	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GFB47_RS03705	COG0285	dihydrofolate synthase activity
GFB47_RS03710	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
GFB47_RS03715	COG1286	toxin biosynthetic process
GFB47_RS03720	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GFB47_RS03730	COG0583	DNA-binding transcription factor activity
GFB47_RS03735	COG0745	RESPONSE REGULATOR receiver
GFB47_RS03740	COG2832	Protein of unknown function (DUF454)
GFB47_RS03745	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GFB47_RS03755	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GFB47_RS03760	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GFB47_RS03815	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GFB47_RS03820	COG2200	EAL domain
GFB47_RS03825	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GFB47_RS03835	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
GFB47_RS03855	COG2356	endonuclease I
GFB47_RS03860	COG2226	methyltransferase
GFB47_RS03870	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GFB47_RS03875	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GFB47_RS03880	COG3139	Protein of unknown function (DUF1315)
GFB47_RS03885	COG0252	asparaginase activity
GFB47_RS03890	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GFB47_RS03890	COG1263	PTS System
GFB47_RS03895	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GFB47_RS03905	COG0616	signal peptide processing
GFB47_RS03910	COG1902	pentaerythritol trinitrate reductase activity
GFB47_RS03910	COG0446	pyridine nucleotide-disulphide oxidoreductase
GFB47_RS03915	COG0778	Nitroreductase
GFB47_RS03920	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GFB47_RS03935	COG3706	GGDEF domain
GFB47_RS03945	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GFB47_RS03945	COG1263	PTS System
GFB47_RS03955	COG2188	Transcriptional regulator
GFB47_RS03980	COG3083	sulfuric ester hydrolase activity
GFB47_RS03985	COG3082	Protein of unknown function (DUF1414)
GFB47_RS03990	COG3081	Nucleoid-associated protein
GFB47_RS03995	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GFB47_RS04000	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GFB47_RS04005	COG2095	MarC family integral membrane protein
GFB47_RS04010	COG1012	belongs to the aldehyde dehydrogenase family
GFB47_RS04010	COG1454	alcohol dehydrogenase
GFB47_RS04025	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
GFB47_RS04030	COG2056	Na+-H+ antiporter family
GFB47_RS04040	COG0346	lactoylglutathione lyase activity
GFB47_RS04045	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GFB47_RS04050	COG4660	Part of a membrane complex involved in electron transport
GFB47_RS04055	COG4659	FMN binding
GFB47_RS04065	COG4656	Part of a membrane complex involved in electron transport
GFB47_RS04075	COG4657	Part of a membrane complex involved in electron transport
GFB47_RS04085	COG0556	nucleotide-excision repair
GFB47_RS04090	COG0391	Required for morphogenesis under gluconeogenic growth conditions
GFB47_RS04095	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GFB47_RS04100	COG0315	cyclic pyranopterin monophosphate synthase activity
GFB47_RS04105	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
GFB47_RS04110	COG0314	molybdopterin synthase activity
GFB47_RS04130	COG0601	transmembrane transport
GFB47_RS04135	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GFB47_RS04150	COG1609	Transcriptional regulator
GFB47_RS04155	COG1609	Transcriptional regulator
GFB47_RS04170	COG1609	Transcriptional regulator
GFB47_RS04175	COG1447	Phosphotransferase system cellobiose-specific component IIA
GFB47_RS04180	COG2723	6-phospho-beta-galactosidase activity
GFB47_RS04185	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GFB47_RS04195	COG1940	carbohydrate kinase activity
GFB47_RS04200	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GFB47_RS04205	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GFB47_RS04210	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GFB47_RS04210	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GFB47_RS04215	COG2723	6-phospho-beta-galactosidase activity
GFB47_RS04220	COG1447	Phosphotransferase system cellobiose-specific component IIA
GFB47_RS04225	COG1609	Transcriptional regulator
GFB47_RS04230	COG2723	6-phospho-beta-galactosidase activity
GFB47_RS04235	COG0745	RESPONSE REGULATOR receiver
GFB47_RS04255	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GFB47_RS04290	COG1566	PFAM secretion protein HlyD family protein
GFB47_RS04295	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GFB47_RS04305	COG1946	Acyl-CoA thioesterase
GFB47_RS04330	COG3706	GGDEF domain
GFB47_RS04405	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GFB47_RS04440	COG4974	Belongs to the 'phage' integrase family
GFB47_RS04480	COG0488	(ABC) transporter
GFB47_RS04485	COG2719	SpoVR family
GFB47_RS04490	COG2718	Belongs to the UPF0229 family
GFB47_RS04495	COG2766	serine protein kinase
GFB47_RS04500	COG3013	Belongs to the UPF0304 family
GFB47_RS04505	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GFB47_RS04510	COG1882	Formate acetyltransferase
GFB47_RS04515	COG3706	GGDEF domain
GFB47_RS04520	COG3706	GGDEF domain
GFB47_RS04525	COG0668	transmembrane transport
GFB47_RS04545	COG4160	amino acid transport
GFB47_RS04550	COG0708	Exodeoxyribonuclease III
GFB47_RS04555	COG4974	Belongs to the 'phage' integrase family
GFB47_RS04645	COG4695	Portal protein
GFB47_RS04780	COG2850	peptidyl-arginine hydroxylation
GFB47_RS04785	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GFB47_RS04790	COG2915	High frequency lysogenization protein hflD homolog
GFB47_RS04795	COG0482	sulfurtransferase activity
GFB47_RS04800	COG1187	pseudouridine synthase activity
GFB47_RS04870	COG2770	Histidine kinase
GFB47_RS04870	COG3437	response regulator, receiver
GFB47_RS04875	COG1278	Cold shock
GFB47_RS04880	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
GFB47_RS04885	COG0542	response to heat
GFB47_RS04890	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GFB47_RS04895	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
GFB47_RS04900	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
GFB47_RS04910	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GFB47_RS04915	COG0539	negative regulation of cytoplasmic translation
GFB47_RS04920	COG0776	regulation of translation
GFB47_RS04925	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
GFB47_RS04930	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
GFB47_RS04955	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GFB47_RS04960	COG4136	ATPase activity
GFB47_RS04970	COG4134	Bacterial extracellular solute-binding protein
GFB47_RS04980	COG1434	Gram-negative-bacterium-type cell wall biogenesis
GFB47_RS04985	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GFB47_RS04990	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
GFB47_RS04995	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
GFB47_RS05010	COG1227	inorganic diphosphatase activity
GFB47_RS05020	COG4172	Belongs to the ABC transporter superfamily
GFB47_RS05030	COG4171	peptide transport system, permease
GFB47_RS05040	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GFB47_RS05045	COG1842	Phage shock protein A
GFB47_RS05060	COG0519	Catalyzes the synthesis of GMP from XMP
GFB47_RS05075	COG0814	amino acid
GFB47_RS05080	COG0564	pseudouridine synthase activity
GFB47_RS05085	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GFB47_RS05095	COG2350	Protein conserved in bacteria
GFB47_RS05100	COG1607	acyl-coa hydrolase
GFB47_RS05105	COG2917	probably involved in intracellular septation
GFB47_RS05110	COG0159	tryptophan synthase activity
GFB47_RS05120	COG0134	indole-3-glycerol-phosphate synthase activity
GFB47_RS05120	COG0135	phosphoribosylanthranilate isomerase activity
GFB47_RS05125	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GFB47_RS05130	COG0512	Glutamine amidotransferase of anthranilate synthase
GFB47_RS05135	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GFB47_RS05140	COG0613	PHP domain protein
GFB47_RS05145	COG0009	L-threonylcarbamoyladenylate synthase
GFB47_RS05165	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GFB47_RS05170	COG0417	DNA replication proofreading
GFB47_RS05175	COG2197	response regulator
GFB47_RS05180	COG0322	excinuclease ABC activity
GFB47_RS05190	COG1022	Amp-dependent synthetase and ligase
GFB47_RS05200	COG0019	diaminopimelate decarboxylase activity
GFB47_RS05230	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GFB47_RS05235	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GFB47_RS05275	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GFB47_RS05300	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
GFB47_RS05325	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GFB47_RS05340	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GFB47_RS05345	COG1448	Aminotransferase
GFB47_RS05350	COG2807	transmembrane transport
GFB47_RS05360	COG0017	Asparaginyl-tRNA synthetase
GFB47_RS05370	COG1760	l-serine dehydratase
GFB47_RS05375	COG0814	amino acid
GFB47_RS05385	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GFB47_RS05400	COG3106	COG3106 Predicted ATPase
GFB47_RS05425	COG1196	nuclear chromosome segregation
GFB47_RS05425	COG3264	Mechanosensitive ion channel
GFB47_RS05430	COG3437	response regulator, receiver
GFB47_RS05430	COG2770	Histidine kinase
GFB47_RS05455	COG1823	symporter activity
GFB47_RS05460	COG1280	lysine exporter protein (LysE YggA)
GFB47_RS05490	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GFB47_RS05495	COG1254	Belongs to the acylphosphatase family
GFB47_RS05500	COG2920	part of a sulfur-relay system
GFB47_RS05505	COG0670	Belongs to the BI1 family
GFB47_RS05520	COG1126	abc transporter atp-binding protein
GFB47_RS05525	COG0765	amino acid transport
GFB47_RS05530	COG4597	amino acid ABC transporter
GFB47_RS05535	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GFB47_RS05545	COG4139	cobalamin transport
GFB47_RS05550	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
GFB47_RS05560	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GFB47_RS05570	COG3040	lipid binding
GFB47_RS05575	COG0745	RESPONSE REGULATOR receiver
GFB47_RS05580	COG2205	protein histidine kinase activity
GFB47_RS05585	COG2194	sulfuric ester hydrolase activity
GFB47_RS05590	COG3713	MltA-interacting MipA family protein
GFB47_RS05595	COG0513	Belongs to the DEAD box helicase family
GFB47_RS05610	COG3122	Protein conserved in bacteria
GFB47_RS05645	COG0625	glutathione transferase activity
GFB47_RS05655	COG0697	spore germination
GFB47_RS05665	COG0351	phosphomethylpyrimidine kinase
GFB47_RS05670	COG1116	anion transmembrane transporter activity
GFB47_RS05675	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GFB47_RS05680	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GFB47_RS05685	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
GFB47_RS05695	COG1301	dicarboxylic acid transport
GFB47_RS05710	COG0303	'Molybdopterin
GFB47_RS05715	COG0746	molybdenum cofactor guanylyltransferase activity
GFB47_RS05720	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GFB47_RS05725	COG4662	Binding-protein-dependent transport system inner membrane component
GFB47_RS05730	COG2998	abc-type tungstate transport system, permease component
GFB47_RS05735	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GFB47_RS05765	COG3383	formate dehydrogenase (NAD+) activity
GFB47_RS05770	COG0437	4 iron, 4 sulfur cluster binding
GFB47_RS05775	COG2864	formate dehydrogenase
GFB47_RS05780	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GFB47_RS05785	COG1793	dna ligase
GFB47_RS05790	COG0534	Mate efflux family protein
GFB47_RS05805	COG0791	NLP P60 protein
GFB47_RS05810	COG1940	carbohydrate kinase activity
GFB47_RS05830	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GFB47_RS05840	COG1177	transmembrane transport
GFB47_RS05845	COG1176	ABC-type spermidine putrescine transport system, permease component I
GFB47_RS05850	COG3842	ATPase activity
GFB47_RS05870	COG0037	tRNA processing
GFB47_RS05875	COG0589	response to stress
GFB47_RS05880	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GFB47_RS05895	COG2217	Heavy metal translocating P-type atpase
GFB47_RS05905	COG2010	Cytochrome c
GFB47_RS05920	COG3278	Belongs to the heme-copper respiratory oxidase family
GFB47_RS05940	COG1067	ATP-dependent peptidase activity
GFB47_RS05945	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GFB47_RS05960	COG0488	(ABC) transporter
GFB47_RS05970	COG0116	Belongs to the methyltransferase superfamily
GFB47_RS05970	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GFB47_RS05980	COG0167	dihydroorotate dehydrogenase activity
GFB47_RS05990	COG0308	aminopeptidase N
GFB47_RS06005	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
GFB47_RS06010	COG1956	GAF domain-containing protein
GFB47_RS06015	COG1132	(ABC) transporter
GFB47_RS06020	COG2995	paraquat-inducible protein a
GFB47_RS06025	COG3008	intermembrane lipid transfer
GFB47_RS06030	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
GFB47_RS06030	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GFB47_RS06060	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GFB47_RS06065	COG1666	GTP binding
GFB47_RS06070	COG2079	MmgE PrpD family protein
GFB47_RS06075	COG0372	Belongs to the citrate synthase family
GFB47_RS06080	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
GFB47_RS06095	COG1280	lysine exporter protein (LysE YggA)
GFB47_RS06100	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
GFB47_RS06105	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GFB47_RS06140	COG1643	Atp-dependent helicase
GFB47_RS06175	COG2925	Exonuclease
GFB47_RS06185	COG1346	cytolysis
GFB47_RS06190	COG0295	cytidine deaminase activity
GFB47_RS06200	COG0500	methyltransferase
GFB47_RS06205	COG0776	regulation of translation
GFB47_RS06210	COG4235	cytochrome complex assembly
GFB47_RS06210	COG3088	subunit of a heme lyase
GFB47_RS06215	COG1138	Cytochrome C-type biogenesis protein
GFB47_RS06220	COG3301	Polysulphide reductase, NrfD
GFB47_RS06225	COG0437	4 iron, 4 sulfur cluster binding
GFB47_RS06230	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
GFB47_RS06235	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
GFB47_RS06240	COG2184	nucleotidyltransferase activity
GFB47_RS06245	COG4235	cytochrome complex assembly
GFB47_RS06250	COG4166	transmembrane transport
GFB47_RS06255	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GFB47_RS06255	COG0072	phenylalanine-tRNA ligase activity
GFB47_RS06260	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GFB47_RS06280	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GFB47_RS06295	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GFB47_RS06310	COG1126	abc transporter atp-binding protein
GFB47_RS06315	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GFB47_RS06320	COG4215	(ABC) transporter
GFB47_RS06325	COG4160	amino acid transport
GFB47_RS06330	COG0277	FAD linked oxidase domain protein
GFB47_RS06330	COG0247	lactate metabolic process
GFB47_RS06345	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GFB47_RS06355	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GFB47_RS06360	COG0281	malic enzyme
GFB47_RS06365	COG2949	membrane
GFB47_RS06370	COG3706	GGDEF domain
GFB47_RS06380	COG0492	ferredoxin-NADP+ reductase activity
GFB47_RS06385	COG4988	ABC transporter
GFB47_RS06390	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GFB47_RS06395	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GFB47_RS06410	COG3070	regulator of competence-specific genes
GFB47_RS06415	COG2431	L-lysine efflux transmembrane transporter activity
GFB47_RS06425	COG0076	glutamate decarboxylase activity
GFB47_RS06430	COG1737	Transcriptional regulator
GFB47_RS06440	COG3273	potassium ion transport
GFB47_RS06440	COG2985	domain, Protein
GFB47_RS06455	COG1960	acyl-CoA dehydrogenase activity
GFB47_RS06465	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GFB47_RS06490	COG2814	Major facilitator Superfamily
GFB47_RS06500	COG2067	long-chain fatty acid transport protein
GFB47_RS06505	COG1061	Type III restriction enzyme res subunit
GFB47_RS06510	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GFB47_RS06515	COG3313	Fe-S protein
GFB47_RS06540	COG0583	DNA-binding transcription factor activity
GFB47_RS06555	COG1032	radical SAM domain protein
GFB47_RS06570	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
GFB47_RS06575	COG2835	tetraacyldisaccharide 4'-kinase activity
GFB47_RS06585	COG1132	(ABC) transporter
GFB47_RS06590	COG0658	competence protein
GFB47_RS06590	COG2333	competence protein COMEC
GFB47_RS06600	COG4591	ABC-type transport system involved in lipoprotein release permease component
GFB47_RS06605	COG1136	(ABC) transporter
GFB47_RS06610	COG4591	ABC-type transport system involved in lipoprotein release permease component
GFB47_RS06615	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GFB47_RS06660	COG1252	NADH dehydrogenase
GFB47_RS06690	COG0537	adenosine 5'-monophosphoramidase activity
GFB47_RS06700	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
GFB47_RS06705	COG0517	IMP dehydrogenase activity
GFB47_RS06705	COG0617	tRNA 3'-terminal CCA addition
GFB47_RS06705	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GFB47_RS06710	COG3153	acetyltransferase
GFB47_RS06710	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GFB47_RS06720	COG2199	diguanylate cyclase activity
GFB47_RS06720	COG2203	Gaf domain
GFB47_RS06735	COG0330	HflC and HflK could
GFB47_RS06770	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
GFB47_RS06775	COG2885	chlorophyll binding
GFB47_RS06780	COG0823	Involved in the tonB-independent uptake of proteins
GFB47_RS06790	COG0848	biopolymer transport protein
GFB47_RS06795	COG0811	peptide transport
GFB47_RS06800	COG0824	Thioesterase
GFB47_RS06810	COG4890	Cyd operon protein YbgT
GFB47_RS06815	COG1294	oxidase, subunit
GFB47_RS06820	COG1271	oxidase subunit
GFB47_RS06825	COG2255	four-way junction helicase activity
GFB47_RS06830	COG0632	four-way junction helicase activity
GFB47_RS06845	COG4106	trans-aconitate 2-methyltransferase activity
GFB47_RS06850	COG0500	methyltransferase
GFB47_RS06855	COG0189	ligase activity
GFB47_RS06855	COG4067	protein conserved in archaea
GFB47_RS06870	COG1435	thymidine kinase activity
GFB47_RS06880	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GFB47_RS06890	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
GFB47_RS06895	COG3012	SEC-C Motif Domain Protein
GFB47_RS06905	COG1566	PFAM secretion protein HlyD family protein
GFB47_RS06915	COG0140	phosphoribosyl-ATP diphosphatase activity
GFB47_RS06915	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GFB47_RS06920	COG0107	imidazoleglycerol-phosphate synthase activity
GFB47_RS06925	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GFB47_RS06930	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GFB47_RS06935	COG0131	Imidazoleglycerol-phosphate dehydratase
GFB47_RS06935	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GFB47_RS06940	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GFB47_RS06945	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GFB47_RS06950	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GFB47_RS06955	COG1757	Na H antiporter
GFB47_RS06965	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GFB47_RS06980	COG1199	ATP-dependent helicase activity
GFB47_RS06995	COG0501	Belongs to the peptidase M48B family
GFB47_RS07000	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
GFB47_RS07010	COG0156	8-amino-7-oxononanoate synthase activity
GFB47_RS07015	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GFB47_RS07025	COG0189	ligase activity
GFB47_RS07025	COG4067	protein conserved in archaea
GFB47_RS07030	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GFB47_RS07035	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GFB47_RS07045	COG1674	ftsk spoiiie
GFB47_RS07050	COG1522	sequence-specific DNA binding
GFB47_RS07070	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GFB47_RS07080	COG2116	formate transmembrane transporter activity
GFB47_RS07085	COG0616	signal peptide processing
GFB47_RS07090	COG1028	Short-chain dehydrogenase reductase Sdr
GFB47_RS07095	COG1940	carbohydrate kinase activity
GFB47_RS07100	COG0469	pyruvate kinase activity
GFB47_RS07110	COG4667	esterase of the alpha-beta hydrolase superfamily
GFB47_RS07115	COG0733	neurotransmitter:sodium symporter activity
GFB47_RS07130	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GFB47_RS07130	COG2190	(PTS) system
GFB47_RS07130	COG1263	PTS System
GFB47_RS07135	COG0084	hydrolase, TatD family'
GFB47_RS07140	COG0470	DNA polymerase III
GFB47_RS07145	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GFB47_RS07150	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GFB47_RS07160	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GFB47_RS07180	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GFB47_RS07190	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GFB47_RS07195	COG1399	metal-binding, possibly nucleic acid-binding protein
GFB47_RS07200	COG0424	maF-like protein
GFB47_RS07205	COG0564	pseudouridine synthase activity
GFB47_RS07210	COG1530	ribonuclease E activity
GFB47_RS07215	COG0659	secondary active sulfate transmembrane transporter activity
GFB47_RS07225	COG2982	Protein involved in outer membrane biogenesis
GFB47_RS07230	COG0717	Belongs to the dCTP deaminase family
GFB47_RS07235	COG0572	uridine kinase
GFB47_RS07240	COG0489	protein tyrosine kinase activity
GFB47_RS07255	COG2186	Transcriptional regulator
GFB47_RS07260	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GFB47_RS07270	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GFB47_RS07275	COG0653	protein targeting
GFB47_RS07280	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GFB47_RS07285	COG3706	GGDEF domain
GFB47_RS07290	COG1122	ATPase activity
GFB47_RS07295	COG4120	Belongs to the binding-protein-dependent transport system permease family
GFB47_RS07310	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GFB47_RS07315	COG0280	phosphate acetyltransferase
GFB47_RS07315	COG0857	belongs to the CobB CobQ family
GFB47_RS07335	COG2855	membrane
GFB47_RS07355	COG2267	carboxylic ester hydrolase activity
GFB47_RS07360	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
GFB47_RS07365	COG1169	isochorismate synthase
GFB47_RS07370	COG0436	Aminotransferase
GFB47_RS07375	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
GFB47_RS07385	COG2267	carboxylic ester hydrolase activity
GFB47_RS07410	COG1596	polysaccharide export
GFB47_RS07410	COG1555	photosystem II stabilization
GFB47_RS07420	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GFB47_RS07425	COG0776	regulation of translation
GFB47_RS07430	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GFB47_RS07435	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GFB47_RS07465	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GFB47_RS07470	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GFB47_RS07475	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GFB47_RS07480	COG2951	lytic endotransglycosylase activity
GFB47_RS07485	COG3100	YcgL domain-containing protein
GFB47_RS07490	COG0850	regulation of cytokinetic process
GFB47_RS07495	COG2894	cell division
GFB47_RS07505	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
GFB47_RS07510	COG0318	PFAM AMP-dependent synthetase and ligase
GFB47_RS07515	COG0596	Alpha beta hydrolase
GFB47_RS07520	COG1214	PFAM Peptidase M22, glycoprotease
GFB47_RS07525	COG1199	ATP-dependent helicase activity
GFB47_RS07530	COG0788	formyltetrahydrofolate deformylase activity
GFB47_RS07565	COG3102	Protein conserved in bacteria
GFB47_RS07570	COG0018	arginyl-trna synthetase
GFB47_RS07575	COG1560	Kdo2-lipid A biosynthetic process
GFB47_RS07585	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
GFB47_RS07590	COG1918	ferrous iron import across plasma membrane
GFB47_RS07600	COG0739	heme binding
GFB47_RS07620	COG1121	(ABC) transporter
GFB47_RS07625	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GFB47_RS07630	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GFB47_RS07635	COG0045	succinate-CoA ligase (ADP-forming) activity
GFB47_RS07640	COG0508	dehydrogenase complex catalyzes the overall conversion of
GFB47_RS07645	COG0567	Dehydrogenase, E1 component
GFB47_RS07655	COG1053	succinate dehydrogenase
GFB47_RS07660	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
GFB47_RS07675	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GFB47_RS07685	COG0033	Phosphoglucomutase
GFB47_RS07690	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
GFB47_RS07700	COG0596	Alpha beta hydrolase
GFB47_RS07710	COG0716	FMN binding
GFB47_RS07720	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GFB47_RS07725	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GFB47_RS07725	COG2190	(PTS) system
GFB47_RS07725	COG1263	PTS System
GFB47_RS07730	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GFB47_RS07735	COG1846	Transcriptional regulator
GFB47_RS07735	COG1940	carbohydrate kinase activity
GFB47_RS07740	COG0475	glutathione-regulated potassium exporter activity
GFB47_RS07745	COG0367	asparagine synthase
GFB47_RS07750	COG0250	Participates in transcription elongation, termination and antitermination
GFB47_RS07760	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
GFB47_RS07765	COG0563	adenylate kinase activity
GFB47_RS07770	COG0326	Molecular chaperone. Has ATPase activity
GFB47_RS07775	COG3710	Transcriptional regulator
GFB47_RS07785	COG0622	Phosphoesterase
GFB47_RS07790	COG1090	epimerase
GFB47_RS07795	COG3118	belongs to the thioredoxin family
GFB47_RS07815	COG3115	cell septum assembly
GFB47_RS07820	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
GFB47_RS07830	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GFB47_RS07840	COG2190	(PTS) system
GFB47_RS07845	COG2837	iron assimilation
GFB47_RS07865	COG1393	Belongs to the ArsC family
GFB47_RS07885	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
GFB47_RS07900	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GFB47_RS07915	COG4783	chaperone-mediated protein folding
GFB47_RS07920	COG1393	Belongs to the ArsC family
GFB47_RS07940	COG0583	DNA-binding transcription factor activity
GFB47_RS07945	COG2130	NADP-dependent
GFB47_RS07950	COG1979	alcohol dehydrogenase
GFB47_RS07965	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GFB47_RS07970	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GFB47_RS07975	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GFB47_RS07980	COG0121	glutamine amidotransferase
GFB47_RS07985	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
GFB47_RS07990	COG1960	acyl-CoA dehydrogenase activity
GFB47_RS08005	COG0328	RNA-DNA hybrid ribonuclease activity
GFB47_RS08010	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GFB47_RS08015	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
GFB47_RS08025	COG2731	YhcH YjgK YiaL family protein
GFB47_RS08030	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GFB47_RS08040	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
GFB47_RS08045	COG0583	DNA-binding transcription factor activity
GFB47_RS08050	COG0657	acetylesterase activity
GFB47_RS08065	COG3141	response to X-ray
GFB47_RS08070	COG2095	MarC family integral membrane protein
GFB47_RS08075	COG2171	N-acyltransferase activity
GFB47_RS08080	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GFB47_RS08085	COG3835	regulator
GFB47_RS08090	COG1929	Belongs to the glycerate kinase type-1 family
GFB47_RS08095	COG1022	Amp-dependent synthetase and ligase
GFB47_RS08100	COG4628	conserved protein (DUF2132)
GFB47_RS08105	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GFB47_RS08110	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GFB47_RS08115	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GFB47_RS08120	COG0560	Phosphoserine phosphatase
GFB47_RS08130	COG0813	purine-nucleoside phosphorylase activity
GFB47_RS08140	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
GFB47_RS08145	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GFB47_RS08150	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GFB47_RS08155	COG0084	hydrolase, TatD family'
GFB47_RS08185	COG3154	lipid carrier protein
GFB47_RS08190	COG0826	peptidase U32
GFB47_RS08195	COG0826	peptidase U32
GFB47_RS08205	COG1185	polyribonucleotide nucleotidyltransferase activity
GFB47_RS08220	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GFB47_RS08225	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GFB47_RS08230	COG0195	Participates in both transcription termination and antitermination
GFB47_RS08235	COG0779	Required for maturation of 30S ribosomal subunits
GFB47_RS08250	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GFB47_RS08255	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GFB47_RS08260	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GFB47_RS08265	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GFB47_RS08270	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
GFB47_RS08275	COG1534	Rna-binding protein
GFB47_RS08285	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GFB47_RS08290	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GFB47_RS08295	COG2027	D-alanyl-D-alanine carboxypeptidase
GFB47_RS08300	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GFB47_RS08305	COG0505	Belongs to the CarA family
GFB47_RS08320	COG0336	Belongs to the RNA methyltransferase TrmD family
GFB47_RS08325	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GFB47_RS08330	COG0228	four-way junction DNA binding
GFB47_RS08335	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GFB47_RS08340	COG4137	Cytochrome C assembly protein
GFB47_RS08345	COG4536	flavin adenine dinucleotide binding
GFB47_RS08350	COG1854	S-ribosylhomocysteine lyase activity
GFB47_RS08365	COG0612	Peptidase, M16
GFB47_RS08370	COG1238	metal cluster binding
GFB47_RS08375	COG1063	alcohol dehydrogenase
GFB47_RS08415	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
GFB47_RS08420	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GFB47_RS08425	COG2137	regulation of response to DNA damage stimulus
GFB47_RS08430	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GFB47_RS08435	COG1546	Belongs to the CinA family
GFB47_RS08440	COG2358	TRAP transporter, solute receptor (TAXI family
GFB47_RS08465	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GFB47_RS08475	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GFB47_RS08480	COG1388	LysM domain
GFB47_RS08480	COG4942	peptidase
GFB47_RS08485	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
GFB47_RS08490	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
GFB47_RS08500	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
GFB47_RS08510	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
GFB47_RS08515	COG0484	heat shock protein binding
GFB47_RS08520	COG0443	Heat shock 70 kDa protein
GFB47_RS08525	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GFB47_RS08530	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GFB47_RS08535	COG0497	DNA recombination
GFB47_RS08540	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GFB47_RS08545	COG2914	Belongs to the UPF0125 (RnfH) family
GFB47_RS08550	COG2867	negative regulation of translational initiation
GFB47_RS08590	COG0513	Belongs to the DEAD box helicase family
GFB47_RS08595	COG1104	cysteine desulfurase activity
GFB47_RS08620	COG0765	amino acid transport
GFB47_RS08630	COG0765	amino acid transport
GFB47_RS08635	COG1126	abc transporter atp-binding protein
GFB47_RS08645	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
GFB47_RS08650	COG0583	DNA-binding transcription factor activity
GFB47_RS08660	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GFB47_RS08660	COG0519	Catalyzes the synthesis of GMP from XMP
GFB47_RS08665	COG0516	GMP reductase activity
GFB47_RS08665	COG0517	IMP dehydrogenase activity
GFB47_RS08680	COG5001	Diguanylate cyclase
GFB47_RS08680	COG3300	MHYT domain
GFB47_RS08690	COG1160	GTP binding
GFB47_RS08695	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GFB47_RS08700	COG2976	Protein conserved in bacteria
GFB47_RS08705	COG0124	histidyl-tRNA synthetase
GFB47_RS08715	COG1426	Protein conserved in bacteria
GFB47_RS08735	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GFB47_RS08740	COG2975	iron-sulfur cluster assembly
GFB47_RS08745	COG0633	Ferredoxin
GFB47_RS08750	COG0443	Heat shock 70 kDa protein
GFB47_RS08755	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
GFB47_RS08765	COG0822	iron-sulfur transferase activity
GFB47_RS08775	COG1959	2 iron, 2 sulfur cluster binding
GFB47_RS08780	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
GFB47_RS08785	COG0483	inositol monophosphate 1-phosphatase activity
GFB47_RS08790	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GFB47_RS08795	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GFB47_RS08800	COG1862	Preprotein translocase
GFB47_RS08810	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GFB47_RS08820	COG0583	DNA-binding transcription factor activity
GFB47_RS08825	COG0450	alkyl hydroperoxide reductase
GFB47_RS08830	COG3142	Participates in the control of copper homeostasis
GFB47_RS08835	COG0704	Plays a role in the regulation of phosphate uptake
GFB47_RS08840	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GFB47_RS08845	COG0573	inorganic phosphate transmembrane transporter activity
GFB47_RS08860	COG5002	protein histidine kinase activity
GFB47_RS08865	COG0745	RESPONSE REGULATOR receiver
GFB47_RS08875	COG0826	peptidase U32
GFB47_RS08880	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GFB47_RS08930	COG0542	response to heat
GFB47_RS08940	COG0564	pseudouridine synthase activity
GFB47_RS08945	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GFB47_RS08950	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GFB47_RS08955	COG0077	Prephenate dehydratase
GFB47_RS08955	COG1605	Chorismate mutase
GFB47_RS08965	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
GFB47_RS08975	COG0488	(ABC) transporter
GFB47_RS08980	COG0739	heme binding
GFB47_RS08990	COG0287	Prephenate dehydrogenase
GFB47_RS08990	COG1605	Chorismate mutase
GFB47_RS08995	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GFB47_RS09000	COG3275	phosphorelay sensor kinase activity
GFB47_RS09005	COG3279	Response regulator of the LytR AlgR family
GFB47_RS09025	COG1966	Carbon starvation protein
GFB47_RS09030	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GFB47_RS09035	COG1047	Peptidyl-prolyl cis-trans
GFB47_RS09040	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GFB47_RS09050	COG0196	riboflavin kinase activity
GFB47_RS09055	COG0728	peptidoglycan biosynthetic process
GFB47_RS09060	COG0268	Binds directly to 16S ribosomal RNA
GFB47_RS09065	COG0640	Transcriptional regulator
GFB47_RS09070	COG0583	DNA-binding transcription factor activity
GFB47_RS09075	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GFB47_RS09085	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
GFB47_RS09090	COG0494	nUDIX hydrolase
GFB47_RS09095	COG3066	DNA modification
GFB47_RS09105	COG0667	Aldo Keto reductase
GFB47_RS09110	COG2204	response regulator
GFB47_RS09115	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GFB47_RS09125	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GFB47_RS09130	COG3097	Belongs to the UPF0267 family
GFB47_RS09140	COG4974	Belongs to the 'phage' integrase family
GFB47_RS09145	COG0716	FMN binding
GFB47_RS09155	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GFB47_RS09160	COG0513	Belongs to the DEAD box helicase family
GFB47_RS09165	COG3022	response to hydroperoxide
GFB47_RS09170	COG1115	amino acid carrier protein
GFB47_RS09185	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GFB47_RS09190	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
GFB47_RS09195	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GFB47_RS09200	COG0083	homoserine kinase activity
GFB47_RS09210	COG0745	RESPONSE REGULATOR receiver
GFB47_RS09215	COG5002	protein histidine kinase activity
GFB47_RS09215	COG2198	Histidine kinase
GFB47_RS09215	COG0784	Response regulator, receiver
GFB47_RS09220	COG5001	Diguanylate cyclase
GFB47_RS09220	COG4251	negative regulation of phosphorylation
GFB47_RS09220	COG3706	GGDEF domain
GFB47_RS09220	COG2203	Gaf domain
GFB47_RS09225	COG0070	glutamate synthase
GFB47_RS09225	COG0069	glutamate synthase activity
GFB47_RS09225	COG0067	glutamate synthase
GFB47_RS09245	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GFB47_RS09250	COG2860	membrane
GFB47_RS09255	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GFB47_RS09260	COG0739	heme binding
GFB47_RS09275	COG0628	permease
GFB47_RS09280	COG2813	Specifically methylates the guanine in position
GFB47_RS09285	COG2205	protein histidine kinase activity
GFB47_RS09285	COG0784	Response regulator, receiver
GFB47_RS09290	COG0747	negative chemotaxis
GFB47_RS09300	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GFB47_RS09305	COG0444	Belongs to the ABC transporter superfamily
GFB47_RS09310	COG4608	Belongs to the ABC transporter superfamily
GFB47_RS09320	COG2971	BadF BadG BcrA BcrD
GFB47_RS09335	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GFB47_RS09340	COG2814	Major facilitator Superfamily
GFB47_RS09350	COG3842	ATPase activity
GFB47_RS09360	COG1840	ABC-type Fe3 transport system, periplasmic component
GFB47_RS09365	COG0004	ammonium transporteR
GFB47_RS09370	COG0347	Belongs to the P(II) protein family
GFB47_RS09375	COG3112	Uncharacterised protein family (UPF0231)
GFB47_RS09380	COG3700	Belongs to the class B bacterial acid phosphatase family
GFB47_RS09390	COG0583	DNA-binding transcription factor activity
GFB47_RS09395	COG0534	Mate efflux family protein
GFB47_RS09405	COG1028	Short-chain dehydrogenase reductase Sdr
GFB47_RS09420	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GFB47_RS09425	COG1349	DNA-binding transcription factor activity
GFB47_RS09440	COG0440	acetolactate synthase activity
GFB47_RS09445	COG0028	Belongs to the TPP enzyme family
GFB47_RS09450	COG0583	DNA-binding transcription factor activity
GFB47_RS09460	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GFB47_RS09465	COG0473	3-isopropylmalate dehydrogenase activity
GFB47_RS09475	COG0066	3-isopropylmalate dehydratase activity
GFB47_RS09485	COG0157	Belongs to the NadC ModD family
GFB47_RS09490	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
GFB47_RS09495	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
GFB47_RS09500	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GFB47_RS09505	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
GFB47_RS09515	COG2967	ApaG domain
GFB47_RS09520	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GFB47_RS09525	COG1289	transmembrane transporter activity
GFB47_RS09535	COG3610	response to peptide
GFB47_RS09540	COG2966	Psort location CytoplasmicMembrane, score
GFB47_RS09545	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GFB47_RS09550	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GFB47_RS09560	COG0142	geranyltranstransferase activity
GFB47_RS09565	COG0039	L-malate dehydrogenase activity
GFB47_RS09570	COG1438	arginine binding
GFB47_RS09580	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GFB47_RS09585	COG0557	exoribonuclease II activity
GFB47_RS09595	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GFB47_RS09595	COG1017	nitric oxide dioxygenase activity
GFB47_RS09600	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GFB47_RS09610	COG0330	HflC and HflK could
GFB47_RS09615	COG0330	HflC and HflK could
GFB47_RS09620	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GFB47_RS09630	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GFB47_RS09635	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GFB47_RS09640	COG0860	N-Acetylmuramoyl-L-alanine amidase
GFB47_RS09645	COG0802	atpase or kinase
GFB47_RS09650	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GFB47_RS09705	COG1162	GTPase activity
GFB47_RS09710	COG0688	phosphatidylethanolamine metabolic process
GFB47_RS09720	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
GFB47_RS09735	COG1053	succinate dehydrogenase
GFB47_RS09740	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GFB47_RS09745	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
GFB47_RS09755	COG0471	metal ion transport
GFB47_RS09765	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
GFB47_RS09770	COG3683	transport system, periplasmic component
GFB47_RS09775	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
GFB47_RS09780	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GFB47_RS09785	COG1509	lysine 2,3-aminomutase activity
GFB47_RS09795	COG2233	PERMEase
GFB47_RS09805	COG3409	Peptidoglycan-binding domain 1 protein
GFB47_RS09805	COG3267	Type II secretory pathway component ExeA
GFB47_RS09810	COG0617	tRNA 3'-terminal CCA addition
GFB47_RS09815	COG1968	undecaprenyl-diphosphatase activity
GFB47_RS09820	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GFB47_RS09825	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GFB47_RS09830	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
GFB47_RS09835	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GFB47_RS09845	COG1610	YqeY-like protein
GFB47_RS09870	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GFB47_RS09875	COG1584	GPR1 FUN34 yaaH family protein
GFB47_RS09895	COG1566	PFAM secretion protein HlyD family protein
GFB47_RS09920	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GFB47_RS09925	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GFB47_RS09945	COG1216	Glycosyl transferase, family 2
GFB47_RS09950	COG2986	histidine ammonia-lyase
GFB47_RS09980	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GFB47_RS09985	COG1028	Short-chain dehydrogenase reductase Sdr
GFB47_RS09990	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GFB47_RS10075	COG0175	sulfate reduction
GFB47_RS10080	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GFB47_RS10085	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GFB47_RS10105	COG0582	viral genome integration into host DNA
GFB47_RS10140	COG5290	Psort location Cytoplasmic, score
GFB47_RS10145	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
GFB47_RS10155	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
GFB47_RS10185	COG0735	belongs to the Fur family
GFB47_RS10190	COG0166	Belongs to the GPI family
GFB47_RS10200	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GFB47_RS10225	COG2965	DNA replication, synthesis of RNA primer
GFB47_RS10230	COG0360	Binds together with S18 to 16S ribosomal RNA
GFB47_RS10235	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GFB47_RS10250	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
GFB47_RS10260	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
GFB47_RS10265	COG1178	ABC-type Fe3 transport system permease component
GFB47_RS10275	COG0163	prenyltransferase activity
GFB47_RS10280	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GFB47_RS10285	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
GFB47_RS10290	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
GFB47_RS10305	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GFB47_RS10315	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
GFB47_RS10325	COG1136	(ABC) transporter
GFB47_RS10340	COG0529	Catalyzes the synthesis of activated sulfate
GFB47_RS10345	COG3273	potassium ion transport
GFB47_RS10345	COG0471	metal ion transport
GFB47_RS10350	COG2895	sulfate adenylyltransferase (ATP) activity
GFB47_RS10355	COG0175	sulfate reduction
GFB47_RS10360	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GFB47_RS10360	COG1648	precorrin-2 dehydrogenase activity
GFB47_RS10365	COG2153	protein acetylation
GFB47_RS10370	COG3266	domain, Protein
GFB47_RS10370	COG3061	Opacity-associated protein A
GFB47_RS10375	COG0545	Peptidyl-prolyl cis-trans isomerase
GFB47_RS10385	COG0203	ribosomal protein L17
GFB47_RS10390	COG0202	RNA polymerase activity
GFB47_RS10395	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GFB47_RS10405	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GFB47_RS10410	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GFB47_RS10415	COG0201	protein transport
GFB47_RS10420	COG0200	Binds to the 23S rRNA
GFB47_RS10425	COG1841	ribosomal large subunit assembly
GFB47_RS10440	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GFB47_RS10445	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GFB47_RS10450	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GFB47_RS10455	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GFB47_RS10460	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GFB47_RS10480	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GFB47_RS10485	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GFB47_RS10490	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GFB47_RS10495	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GFB47_RS10500	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GFB47_RS10505	COG0089	rRNA binding
GFB47_RS10510	COG0088	Forms part of the polypeptide exit tunnel
GFB47_RS10515	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GFB47_RS10525	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GFB47_RS10530	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GFB47_RS10550	COG2923	Belongs to the DsrF TusC family
GFB47_RS10555	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
GFB47_RS10560	COG2964	Protein conserved in bacteria
GFB47_RS10565	COG0545	Peptidyl-prolyl cis-trans isomerase
GFB47_RS10570	COG2900	Belongs to the SlyX family
GFB47_RS10575	COG1047	Peptidyl-prolyl cis-trans
GFB47_RS10580	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
GFB47_RS10590	COG2249	NAD(P)H dehydrogenase (quinone) activity
GFB47_RS10595	COG0488	(ABC) transporter
GFB47_RS10605	COG3089	Belongs to the UPF0270 family
GFB47_RS10610	COG3954	Phosphoribulokinase
GFB47_RS10615	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GFB47_RS10620	COG0814	amino acid
GFB47_RS10625	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GFB47_RS10630	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
GFB47_RS10635	COG1561	YicC-like family, N-terminal region
GFB47_RS10670	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GFB47_RS10690	COG1902	pentaerythritol trinitrate reductase activity
GFB47_RS10700	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GFB47_RS10705	COG0194	GDP metabolic process
GFB47_RS10715	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GFB47_RS10735	COG0180	Tryptophanyl-tRNA synthetase
GFB47_RS10740	COG0546	phosphoglycolate phosphatase activity
GFB47_RS10745	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GFB47_RS10750	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GFB47_RS10755	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GFB47_RS10765	COG1040	competence protein
GFB47_RS10775	COG3038	cytochrome b561
GFB47_RS10780	COG1218	3'(2'),5'-bisphosphate nucleotidase
GFB47_RS10785	COG0494	nUDIX hydrolase
GFB47_RS10795	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
GFB47_RS10800	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
GFB47_RS10805	COG3156	type II secretion system protein K
GFB47_RS10810	COG4795	General secretion pathway protein
GFB47_RS10815	COG2165	general secretion pathway protein
GFB47_RS10820	COG2165	general secretion pathway protein
GFB47_RS10825	COG2165	general secretion pathway protein
GFB47_RS10830	COG1459	type II secretion system
GFB47_RS10835	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GFB47_RS10845	COG3031	protein transport across the cell outer membrane
GFB47_RS10850	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GFB47_RS10855	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GFB47_RS10860	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
GFB47_RS10870	COG0456	acetyltransferase
GFB47_RS10875	COG1490	D-aminoacyl-tRNA deacylase activity
GFB47_RS10885	COG1217	gtp-binding protein TYPA
GFB47_RS10895	COG0174	glutamine synthetase
GFB47_RS10905	COG3852	Histidine kinase
GFB47_RS10940	COG0218	Necessary for normal cell division and for the maintenance of normal septation
GFB47_RS10945	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GFB47_RS10945	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GFB47_RS10950	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
GFB47_RS10960	COG0514	ATP-dependent DNA helicase (RecQ)
GFB47_RS10965	COG2962	Rard protein
GFB47_RS10970	COG1280	lysine exporter protein (LysE YggA)
GFB47_RS10975	COG3678	ATP-independent chaperone mediated protein folding
GFB47_RS10980	COG0745	RESPONSE REGULATOR receiver
GFB47_RS10985	COG2205	protein histidine kinase activity
GFB47_RS10990	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GFB47_RS11000	COG1027	Aspartate ammonia-lyase
GFB47_RS11005	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GFB47_RS11020	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
GFB47_RS11025	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GFB47_RS11040	COG0673	inositol 2-dehydrogenase activity
GFB47_RS11045	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GFB47_RS11050	COG0601	transmembrane transport
GFB47_RS11100	COG1309	transcriptional regulator
GFB47_RS11105	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GFB47_RS11110	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GFB47_RS11115	COG2960	long-chain fatty acid transporting porin activity
GFB47_RS11125	COG0583	DNA-binding transcription factor activity
GFB47_RS11170	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GFB47_RS11175	COG1739	Uncharacterized protein family UPF0029
GFB47_RS11185	COG0183	Belongs to the thiolase family
GFB47_RS11195	COG0181	hydroxymethylbilane synthase activity
GFB47_RS11200	COG1587	Uroporphyrinogen-III synthase
GFB47_RS11205	COG2959	enzyme of heme biosynthesis
GFB47_RS11210	COG3071	HemY protein
GFB47_RS11250	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GFB47_RS11265	COG0408	coproporphyrinogen oxidase activity
GFB47_RS11270	COG0009	L-threonylcarbamoyladenylate synthase
GFB47_RS11275	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GFB47_RS11280	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GFB47_RS11285	COG0551	DNA topoisomerase type I activity
GFB47_RS11290	COG2922	Belongs to the Smg family
GFB47_RS11295	COG0758	DNA mediated transformation
GFB47_RS11300	COG1652	LysM domain
GFB47_RS11305	COG0242	peptide deformylase activity
GFB47_RS11315	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GFB47_RS11315	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GFB47_RS11320	COG0569	domain protein
GFB47_RS11325	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GFB47_RS11330	COG1272	protein, Hemolysin III
GFB47_RS11340	COG3084	Protein conserved in bacteria
GFB47_RS11350	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GFB47_RS11355	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GFB47_RS11360	COG0606	chelatase, subunit chli
GFB47_RS11370	COG3978	acetolactate synthase activity
GFB47_RS11395	COG0583	DNA-binding transcription factor activity
GFB47_RS11400	COG2814	Major facilitator Superfamily
GFB47_RS11410	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GFB47_RS11415	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GFB47_RS11420	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GFB47_RS11430	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GFB47_RS11435	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GFB47_RS11460	COG1475	DNA binding
GFB47_RS11465	COG1192	Involved in chromosome partitioning
GFB47_RS11470	COG0357	Ribosomal RNA small subunit methyltransferase G
GFB47_RS11475	COG0445	tRNA wobble uridine modification
GFB47_RS11480	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GFB47_RS11485	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GFB47_RS11490	COG0706	membrane insertase activity
GFB47_RS11505	COG0230	Belongs to the bacterial ribosomal protein bL34 family
GFB47_RS11510	COG4178	(ABC) transporter
GFB47_RS11525	COG1444	tRNA N-acetyltransferase activity
GFB47_RS11530	COG3383	formate dehydrogenase (NAD+) activity
GFB47_RS11555	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GFB47_RS11580	COG1803	Methylglyoxal synthase
GFB47_RS11580	COG1597	lipid kinase activity
GFB47_RS11585	COG0697	spore germination
GFB47_RS11615	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GFB47_RS11615	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GFB47_RS11620	COG0509	glycine decarboxylation via glycine cleavage system
GFB47_RS11655	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GFB47_RS11665	COG0702	epimerase
GFB47_RS11675	COG1067	ATP-dependent peptidase activity
GFB47_RS11730	COG0243	molybdopterin cofactor binding
GFB47_RS11735	COG0437	4 iron, 4 sulfur cluster binding
GFB47_RS11740	COG3302	dmso reductase anchor subunit
GFB47_RS11745	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GFB47_RS11810	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GFB47_RS11815	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GFB47_RS11860	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GFB47_RS11870	COG1012	belongs to the aldehyde dehydrogenase family
GFB47_RS11880	COG0583	DNA-binding transcription factor activity
GFB47_RS11890	COG0477	Major facilitator Superfamily
GFB47_RS11895	COG0786	glutamate:sodium symporter activity
GFB47_RS11905	COG4948	Mandelate Racemase Muconate Lactonizing
GFB47_RS11920	COG2866	Carboxypeptidase
GFB47_RS11930	COG0471	metal ion transport
GFB47_RS11960	COG0625	glutathione transferase activity
GFB47_RS11970	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
GFB47_RS11985	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GFB47_RS11985	COG1565	acr, cog1565
GFB47_RS11995	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
GFB47_RS12025	COG0109	protoheme IX farnesyltransferase activity
GFB47_RS12050	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GFB47_RS12050	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
GFB47_RS12050	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GFB47_RS12055	COG1105	Belongs to the carbohydrate kinase PfkB family
GFB47_RS12060	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GFB47_RS12060	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GFB47_RS12065	COG1609	Transcriptional regulator
GFB47_RS12085	COG0513	Belongs to the DEAD box helicase family
GFB47_RS12095	COG0010	Belongs to the arginase family
GFB47_RS12100	COG1166	arginine decarboxylase activity
GFB47_RS12110	COG0574	Belongs to the PEP-utilizing enzyme family
GFB47_RS12110	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GFB47_RS12115	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
GFB47_RS12125	COG3604	Transcriptional regulator
GFB47_RS12130	COG0426	domain, Protein
GFB47_RS12130	COG1773	rubredoxin
GFB47_RS12135	COG0446	pyridine nucleotide-disulphide oxidoreductase
GFB47_RS12155	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
GFB47_RS12180	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GFB47_RS12185	COG0583	DNA-binding transcription factor activity
GFB47_RS12190	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
GFB47_RS12200	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GFB47_RS12230	COG2272	Belongs to the type-B carboxylesterase lipase family
GFB47_RS12235	COG1968	undecaprenyl-diphosphatase activity
GFB47_RS12240	COG0513	Belongs to the DEAD box helicase family
GFB47_RS12245	COG3314	Sporulation integral membrane protein YlbJ
GFB47_RS12275	COG3257	ureidoglycine aminohydrolase activity
GFB47_RS12285	COG2186	Transcriptional regulator
GFB47_RS12295	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GFB47_RS12300	COG3960	tartronate-semialdehyde synthase activity
GFB47_RS12305	COG3622	Belongs to the hyi family
GFB47_RS12310	COG2084	Dehydrogenase
GFB47_RS12315	COG1309	transcriptional regulator
GFB47_RS12320	COG1902	pentaerythritol trinitrate reductase activity
GFB47_RS12325	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GFB47_RS12350	COG5492	domain, Protein
GFB47_RS12350	COG4932	domain protein
GFB47_RS12370	COG2200	EAL domain
GFB47_RS12390	COG1187	pseudouridine synthase activity
GFB47_RS12435	COG2814	Major facilitator Superfamily
GFB47_RS12440	COG0583	DNA-binding transcription factor activity
GFB47_RS12445	COG1011	Hydrolase
GFB47_RS12450	COG1846	Transcriptional regulator
GFB47_RS12455	COG2113	Glycine betaine
GFB47_RS12460	COG4176	ABC-type proline glycine betaine transport system permease component
GFB47_RS12475	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GFB47_RS12490	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
GFB47_RS12495	COG2926	Belongs to the UPF0265 family
GFB47_RS12500	COG3132	Protein of unknown function, DUF480
GFB47_RS12505	COG2827	Endonuclease containing a URI domain
GFB47_RS12510	COG2223	nitrite transmembrane transporter activity
GFB47_RS12515	COG3279	Response regulator of the LytR AlgR family
GFB47_RS12520	COG3275	phosphorelay sensor kinase activity
GFB47_RS12525	COG1648	precorrin-2 dehydrogenase activity
GFB47_RS12525	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GFB47_RS12530	COG2116	formate transmembrane transporter activity
GFB47_RS12535	COG2146	nitrite reductase [NAD(P)H] activity
GFB47_RS12540	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GFB47_RS12550	COG3005	denitrification pathway
GFB47_RS12560	COG0243	molybdopterin cofactor binding
GFB47_RS12575	COG3850	Histidine kinase
GFB47_RS12580	COG2197	response regulator
GFB47_RS12595	COG2252	PERMEase
GFB47_RS12600	COG2351	hydroxyisourate hydrolase activity
GFB47_RS12635	COG0243	molybdopterin cofactor binding
GFB47_RS12640	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GFB47_RS12640	COG1648	precorrin-2 dehydrogenase activity
GFB47_RS12655	COG4807	Protein conserved in bacteria
GFB47_RS12670	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GFB47_RS12710	COG0420	3'-5' exonuclease activity
GFB47_RS12715	COG0419	ATPase involved in DNA repair
GFB47_RS12720	COG0179	Fumarylacetoacetate (FAA) hydrolase
GFB47_RS12755	COG2824	Alkylphosphonate utilization operon protein PhnA
GFB47_RS12815	COG2932	Transcriptional regulator
GFB47_RS12825	COG2801	Transposase and inactivated derivatives
GFB47_RS12935	COG0640	Transcriptional regulator
GFB47_RS12950	COG4373	Mu-like prophage FluMu protein gp28
GFB47_RS12955	COG4383	Mu-like prophage protein gp29
GFB47_RS12975	COG4397	Mu-like prophage major head subunit gpT
GFB47_RS13005	COG4386	tail sheath protein
GFB47_RS13015	COG4518	Phage tail assembly chaperone proteins, E, or 41 or 14
GFB47_RS13045	COG3299	homolog of phage Mu protein gp47
GFB47_RS13050	COG3778	Protein conserved in bacteria
GFB47_RS13070	COG2181	nitrate reductase activity
GFB47_RS13075	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
GFB47_RS13085	COG2197	response regulator
GFB47_RS13090	COG1803	Methylglyoxal synthase
GFB47_RS13115	COG0516	GMP reductase activity
GFB47_RS13120	COG4974	Belongs to the 'phage' integrase family
GFB47_RS13130	COG0210	DNA helicase
GFB47_RS13145	COG2304	oxidoreductase activity
GFB47_RS13160	COG0714	Associated with various cellular activities
GFB47_RS13170	COG3530	Putative quorum-sensing-regulated virulence factor
GFB47_RS13175	COG0561	phosphatase activity
GFB47_RS13180	COG4804	nuclease activity
GFB47_RS13185	COG4989	oxidoreductase activity
GFB47_RS13200	COG0814	amino acid
GFB47_RS13205	COG2964	Protein conserved in bacteria
GFB47_RS13225	COG2897	thiosulfate sulfurtransferase activity
GFB47_RS13240	COG1346	cytolysis
GFB47_RS13245	COG1380	Effector of murein hydrolase LrgA
GFB47_RS13250	COG0583	DNA-binding transcription factor activity
GFB47_RS13260	COG0004	ammonium transporteR
GFB47_RS13265	COG0513	Belongs to the DEAD box helicase family
GFB47_RS13275	COG0488	(ABC) transporter
GFB47_RS13290	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GFB47_RS13290	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GFB47_RS13290	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GFB47_RS13295	COG2207	Transcriptional regulator
GFB47_RS13305	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GFB47_RS13310	COG0561	phosphatase activity
GFB47_RS13315	COG3593	DNA synthesis involved in DNA repair
GFB47_RS13320	COG0737	Belongs to the 5'-nucleotidase family
GFB47_RS13330	COG0302	gtp cyclohydrolase
GFB47_RS13340	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GFB47_RS13345	COG0545	Peptidyl-prolyl cis-trans isomerase
GFB47_RS13370	COG0546	phosphoglycolate phosphatase activity
GFB47_RS13375	COG0038	chloride channel
GFB47_RS13380	COG0523	cobalamin synthesis protein
GFB47_RS13395	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
GFB47_RS13400	COG0494	nUDIX hydrolase
GFB47_RS13405	COG0714	Associated with various cellular activities
GFB47_RS13425	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GFB47_RS13430	COG5001	Diguanylate cyclase
GFB47_RS13440	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GFB47_RS13445	COG3038	cytochrome b561
GFB47_RS13450	COG2353	YceI-like domain
GFB47_RS13480	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
GFB47_RS13490	COG3721	Heme iron utilization protein
GFB47_RS13495	COG0748	coenzyme F420 binding
GFB47_RS13500	COG2050	protein possibly involved in aromatic compounds catabolism
GFB47_RS13510	COG4533	DNA binding
GFB47_RS13525	COG0348	domain, Protein
GFB47_RS13535	COG0720	synthase
GFB47_RS13540	COG0602	queuosine metabolic process
GFB47_RS13545	COG3118	belongs to the thioredoxin family
GFB47_RS13550	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GFB47_RS13580	COG4771	TonB-dependent receptor
GFB47_RS13580	COG1629	transport
GFB47_RS13585	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GFB47_RS13585	COG1042	CoA-binding domain protein
GFB47_RS13585	COG0045	succinate-CoA ligase (ADP-forming) activity
GFB47_RS13595	COG1181	Belongs to the D-alanine--D-alanine ligase family
GFB47_RS13620	COG3085	chromosome segregation
GFB47_RS13625	COG0583	DNA-binding transcription factor activity
GFB47_RS13635	COG3140	Belongs to the UPF0181 family
GFB47_RS13655	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
GFB47_RS13660	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
GFB47_RS13710	COG0521	Mo-molybdopterin cofactor biosynthetic process
GFB47_RS13715	COG0366	Alpha amylase catalytic
GFB47_RS13720	COG1215	transferase activity, transferring glycosyl groups
GFB47_RS13725	COG3769	mannosylglycerate metabolic process
GFB47_RS13730	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
GFB47_RS13735	COG4149	molybdate abc transporter
GFB47_RS13740	COG0725	ABC transporter, periplasmic molybdate-binding protein
GFB47_RS13745	COG1492	cobalamin metabolic process
GFB47_RS13750	COG0741	lytic transglycosylase activity
GFB47_RS13755	COG0189	ligase activity
GFB47_RS13755	COG4067	protein conserved in archaea
GFB47_RS13765	COG0602	queuosine metabolic process
GFB47_RS13785	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
GFB47_RS13790	COG4181	ATPase activity
GFB47_RS13800	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GFB47_RS13820	COG1451	nucleotide metabolic process
GFB47_RS13845	COG0251	oxidation-reduction process
GFB47_RS13850	COG3681	Belongs to the UPF0597 family
GFB47_RS13855	COG2964	Protein conserved in bacteria
GFB47_RS13880	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GFB47_RS13880	COG1648	precorrin-2 dehydrogenase activity
GFB47_RS13890	COG1869	D-ribose catabolic process
GFB47_RS13895	COG1129	ABC transporter
GFB47_RS13900	COG1172	Belongs to the binding-protein-dependent transport system permease family
GFB47_RS13905	COG1879	ABC-type sugar transport system periplasmic component
GFB47_RS13910	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GFB47_RS13915	COG1609	Transcriptional regulator
GFB47_RS13930	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GFB47_RS13940	COG0513	Belongs to the DEAD box helicase family
GFB47_RS13950	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GFB47_RS13955	COG0513	Belongs to the DEAD box helicase family
GFB47_RS13960	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
GFB47_RS13975	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GFB47_RS13980	COG1151	hydroxylamine reductase activity
GFB47_RS13995	COG0210	DNA helicase
GFB47_RS14000	COG1289	transmembrane transporter activity
GFB47_RS14010	COG1131	(ABC) transporter
GFB47_RS14015	COG0842	Transport permease protein
GFB47_RS14030	COG0110	maltose O-acetyltransferase activity
GFB47_RS14035	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GFB47_RS14130	COG0402	S-adenosylhomocysteine deaminase activity
GFB47_RS14140	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GFB47_RS14175	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GFB47_RS14180	COG0569	domain protein
GFB47_RS14185	COG0668	transmembrane transport
GFB47_RS14195	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
GFB47_RS14200	COG0826	peptidase U32
GFB47_RS14210	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GFB47_RS14225	COG1278	Cold shock
GFB47_RS14230	COG1278	Cold shock
GFB47_RS14300	COG0628	permease
GFB47_RS14305	COG0243	molybdopterin cofactor binding
GFB47_RS14310	COG3005	denitrification pathway
GFB47_RS14330	COG1063	alcohol dehydrogenase
GFB47_RS14445	COG4220	transposase activity
GFB47_RS14460	COG3772	lysozyme
GFB47_RS14470	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
GFB47_RS14475	COG1403	HNH endonuclease
GFB47_RS14600	COG0582	viral genome integration into host DNA
GFB47_RS14605	COG1063	alcohol dehydrogenase
GFB47_RS14620	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GFB47_RS14630	COG3005	denitrification pathway
GFB47_RS14650	COG0709	Synthesizes selenophosphate from selenide and ATP
GFB47_RS14655	COG2897	thiosulfate sulfurtransferase activity
GFB47_RS14715	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GFB47_RS14720	COG1072	(Pantothenic acid kinase))
GFB47_RS14730	COG1063	alcohol dehydrogenase
GFB47_RS14735	COG2213	PTS system mannitol-specific
GFB47_RS14740	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GFB47_RS14745	COG2017	converts alpha-aldose to the beta-anomer
GFB47_RS14750	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GFB47_RS14755	COG1085	galactose-1-phosphate uridylyltransferase
GFB47_RS14760	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GFB47_RS14775	COG0737	Belongs to the 5'-nucleotidase family
GFB47_RS14790	COG5413	integral membrane protein
GFB47_RS14815	COG2354	Protein conserved in bacteria
GFB47_RS14820	COG0730	response to heat
GFB47_RS14825	COG0583	DNA-binding transcription factor activity
GFB47_RS14830	COG0642	Histidine kinase
GFB47_RS14840	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GFB47_RS14845	COG2194	sulfuric ester hydrolase activity
GFB47_RS14850	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GFB47_RS14860	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GFB47_RS14865	COG0573	inorganic phosphate transmembrane transporter activity
GFB47_RS14875	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GFB47_RS14885	COG0573	inorganic phosphate transmembrane transporter activity
GFB47_RS14890	COG0581	inorganic phosphate transmembrane transporter activity
GFB47_RS14895	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GFB47_RS14915	COG0297	glycogen (starch) synthase activity
GFB47_RS14915	COG0438	transferase activity, transferring glycosyl groups
GFB47_RS14920	COG0438	transferase activity, transferring glycosyl groups
GFB47_RS14945	COG1596	polysaccharide export
GFB47_RS14955	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GFB47_RS14985	COG1714	RDD family
GFB47_RS14995	COG0739	heme binding
GFB47_RS15000	COG3217	Mosc domain protein beta barrel domain protein
GFB47_RS15000	COG0633	Ferredoxin
GFB47_RS15005	COG0418	dihydroorotase activity
GFB47_RS15020	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GFB47_RS15025	COG0640	Transcriptional regulator
GFB47_RS15030	COG2759	Belongs to the formate--tetrahydrofolate ligase family
GFB47_RS15055	COG2176	DNA-directed DNA polymerase activity
GFB47_RS15060	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GFB47_RS15065	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
GFB47_RS15080	COG0517	IMP dehydrogenase activity
GFB47_RS15090	COG1028	Short-chain dehydrogenase reductase Sdr
GFB47_RS15095	COG1917	Cupin 2, conserved barrel domain protein
GFB47_RS15135	COG3778	Protein conserved in bacteria
GFB47_RS15170	COG4518	Phage tail assembly chaperone proteins, E, or 41 or 14
GFB47_RS15180	COG4386	tail sheath protein
GFB47_RS15210	COG4397	Mu-like prophage major head subunit gpT
GFB47_RS15230	COG4383	Mu-like prophage protein gp29
GFB47_RS15235	COG4373	Mu-like prophage FluMu protein gp28
GFB47_RS15250	COG0640	Transcriptional regulator
GFB47_RS15355	COG2842	Transposition protein
GFB47_RS15360	COG2801	Transposase and inactivated derivatives
GFB47_RS15370	COG2932	Transcriptional regulator
GFB47_RS15375	COG1312	Catalyzes the dehydration of D-mannonate
GFB47_RS15380	COG0246	Mannitol dehydrogenase
GFB47_RS15385	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GFB47_RS15395	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
GFB47_RS15405	COG2721	sulfolactate sulfo-lyase activity
GFB47_RS15415	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
GFB47_RS15420	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GFB47_RS15425	COG0800	Aldolase
GFB47_RS15435	COG1904	glucuronate isomerase
GFB47_RS15445	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GFB47_RS15460	COG0517	IMP dehydrogenase activity
GFB47_RS15465	COG2186	Transcriptional regulator
GFB47_RS15495	COG1917	Cupin 2, conserved barrel domain protein
GFB47_RS15500	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GFB47_RS15505	COG0800	Aldolase
GFB47_RS15515	COG0789	Transcriptional regulator
GFB47_RS15520	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GFB47_RS15540	COG0673	inositol 2-dehydrogenase activity
GFB47_RS15545	COG4948	Mandelate Racemase Muconate Lactonizing
GFB47_RS15565	COG2814	Major facilitator Superfamily
GFB47_RS15580	COG1363	Peptidase, m42
GFB47_RS15595	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GFB47_RS15605	COG0523	cobalamin synthesis protein
GFB47_RS15615	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
GFB47_RS15625	COG0189	ligase activity
GFB47_RS15625	COG4067	protein conserved in archaea
GFB47_RS15630	COG0189	ligase activity
GFB47_RS15645	COG1335	isochorismatase
GFB47_RS15650	COG3123	guanosine phosphorylase activity
GFB47_RS15665	COG0531	amino acid
GFB47_RS15695	COG1999	signal sequence binding
GFB47_RS15720	COG0456	acetyltransferase
GFB47_RS15725	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GFB47_RS15730	COG0662	Cupin 2, conserved barrel domain protein
GFB47_RS15735	COG0527	aspartate kinase activity
GFB47_RS15775	COG1012	belongs to the aldehyde dehydrogenase family
GFB47_RS15780	COG3724	N-succinylarginine dihydrolase activity
GFB47_RS15785	COG2988	succinylglutamate desuccinylase activity
GFB47_RS15795	COG4680	protein conserved in bacteria
GFB47_RS15800	COG5499	transcription regulator containing HTH domain
GFB47_RS15805	COG1760	l-serine dehydratase
GFB47_RS15820	COG1176	ABC-type spermidine putrescine transport system, permease component I
GFB47_RS15830	COG3842	ATPase activity
GFB47_RS15850	COG0513	Belongs to the DEAD box helicase family
GFB47_RS15855	COG2814	Major facilitator Superfamily
GFB47_RS15890	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
GFB47_RS15895	COG0804	urea catabolic process
GFB47_RS15900	COG0832	Belongs to the urease beta subunit family
GFB47_RS15905	COG0831	urea catabolic process
GFB47_RS15910	COG0829	nickel cation binding
GFB47_RS15915	COG0300	oxidoreductase activity
GFB47_RS15920	COG1396	sequence-specific DNA binding
GFB47_RS15925	COG3550	peptidyl-serine autophosphorylation
GFB47_RS15955	COG1454	alcohol dehydrogenase
GFB47_RS15970	COG0564	pseudouridine synthase activity
GFB47_RS15975	COG0110	maltose O-acetyltransferase activity
GFB47_RS15980	COG2095	MarC family integral membrane protein
GFB47_RS16000	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GFB47_RS16005	COG0653	protein targeting
GFB47_RS16015	COG0534	Mate efflux family protein
GFB47_RS16025	COG1640	4-alpha-glucanotransferase
GFB47_RS16035	COG0583	DNA-binding transcription factor activity
GFB47_RS16040	COG1902	pentaerythritol trinitrate reductase activity
GFB47_RS16060	COG3833	ABC-type maltose transport systems, permease component
GFB47_RS16065	COG1175	transmembrane transport
GFB47_RS16075	COG3842	ATPase activity
GFB47_RS16085	COG4580	involved in the transport of maltose and maltodextrins
GFB47_RS16095	COG2084	Dehydrogenase