locus-tag	class	description
OO774_RS00010	COG0592	DNA-directed DNA polymerase activity
OO774_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
OO774_RS00020	COG0187	DNA topoisomerase II activity
OO774_RS00025	COG0071	Belongs to the small heat shock protein (HSP20) family
OO774_RS00030	COG3977	Valine--pyruvate aminotransferase
OO774_RS00035	COG0366	Alpha amylase catalytic
OO774_RS00040	COG0751	glycine-tRNA ligase activity
OO774_RS00050	COG2119	membrane
OO774_RS00060	COG0425	Belongs to the sulfur carrier protein TusA family
OO774_RS00075	COG0604	alcohol dehydrogenase
OO774_RS00080	COG0183	Belongs to the thiolase family
OO774_RS00085	COG1024	Enoyl-CoA hydratase
OO774_RS00085	COG1250	3-hydroxyacyl-CoA dehydrogenase
OO774_RS00090	COG1739	Uncharacterized protein family UPF0029
OO774_RS00095	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
OO774_RS00150	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
OO774_RS00160	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
OO774_RS00165	COG2104	thiamine diphosphate biosynthetic process
OO774_RS00170	COG2022	thiamine diphosphate biosynthetic process
OO774_RS00180	COG0006	proline dipeptidase activity
OO774_RS00180	COG0006	proline dipeptidase activity
OO774_RS00210	COG3220	belongs to the UPF0276 family
OO774_RS00220	COG0210	DNA helicase
OO774_RS00225	COG0405	Gamma-glutamyltransferase
OO774_RS00230	COG1280	lysine exporter protein (LysE YggA)
OO774_RS00240	COG2962	Rard protein
OO774_RS00245	COG0514	ATP-dependent DNA helicase (RecQ)
OO774_RS00255	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
OO774_RS00260	COG0248	Ppx GppA phosphatase
OO774_RS00265	COG0513	Belongs to the DEAD box helicase family
OO774_RS00270	COG3118	belongs to the thioredoxin family
OO774_RS00285	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
OO774_RS00380	COG3071	HemY protein
OO774_RS00385	COG2959	enzyme of heme biosynthesis
OO774_RS00390	COG1587	Uroporphyrinogen-III synthase
OO774_RS00395	COG0181	hydroxymethylbilane synthase activity
OO774_RS00405	COG1965	Belongs to the frataxin family
OO774_RS00415	COG0019	diaminopimelate decarboxylase activity
OO774_RS00420	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
OO774_RS00430	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
OO774_RS00435	COG1011	Hydrolase
OO774_RS00440	COG3148	PFAM DTW domain containing protein
OO774_RS00455	COG0561	phosphatase activity
OO774_RS00460	COG2267	carboxylic ester hydrolase activity
OO774_RS00465	COG1280	lysine exporter protein (LysE YggA)
OO774_RS00470	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
OO774_RS00475	COG0640	Transcriptional regulator
OO774_RS00480	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
OO774_RS00525	COG0742	ribosomal rna small subunit methyltransferase
OO774_RS00530	COG0552	protein localization to endoplasmic reticulum
OO774_RS00535	COG2884	Cell division ATP-binding protein ftsE
OO774_RS00540	COG2177	Part of the ABC transporter FtsEX involved in
OO774_RS00555	COG0705	Rhomboid family
OO774_RS00560	COG1580	Controls the rotational direction of flagella during chemotaxis
OO774_RS00565	COG3161	chorismate lyase activity
OO774_RS00570	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
OO774_RS00575	COG2937	Belongs to the GPAT DAPAT family
OO774_RS00580	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
OO774_RS00585	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
OO774_RS00590	COG0534	Mate efflux family protein
OO774_RS00595	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OO774_RS00620	COG4206	TonB-dependent receptor
OO774_RS00665	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OO774_RS00675	COG0812	UDP-N-acetylmuramate dehydrogenase activity
OO774_RS00715	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
OO774_RS00720	COG0250	Participates in transcription elongation, termination and antitermination
OO774_RS00735	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
OO774_RS00740	COG0222	ribosome binding
OO774_RS00745	COG0085	RNA polymerase activity
OO774_RS00750	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
OO774_RS00755	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
OO774_RS00760	COG2816	NAD+ diphosphatase activity
OO774_RS00765	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
OO774_RS00770	COG1573	uracil-dna glycosylase
OO774_RS00780	COG3068	Protein conserved in bacteria
OO774_RS00785	COG1253	flavin adenine dinucleotide binding
OO774_RS00800	COG0151	Belongs to the GarS family
OO774_RS00805	COG0138	bifunctional purine biosynthesis protein purh
OO774_RS00815	COG3710	Transcriptional regulator
OO774_RS00900	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
OO774_RS00905	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OO774_RS00915	COG0439	Biotin carboxylase
OO774_RS00920	COG0511	ligase activity, forming carbon-carbon bonds
OO774_RS00925	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
OO774_RS00930	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OO774_RS00945	COG2814	Major facilitator Superfamily
OO774_RS00950	COG0784	Response regulator, receiver
OO774_RS00950	COG2198	Histidine kinase
OO774_RS00950	COG2205	protein histidine kinase activity
OO774_RS00970	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OO774_RS00980	COG3263	regulation of cellular component size
OO774_RS00990	COG4232	protein-disulfide reductase activity
OO774_RS00995	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
OO774_RS01000	COG1027	Aspartate ammonia-lyase
OO774_RS01010	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
OO774_RS01020	COG2205	protein histidine kinase activity
OO774_RS01025	COG0745	RESPONSE REGULATOR receiver
OO774_RS01040	COG0205	6-phosphofructokinase activity
OO774_RS01045	COG0534	Mate efflux family protein
OO774_RS01055	COG0459	protein refolding
OO774_RS01065	COG1509	lysine 2,3-aminomutase activity
OO774_RS01070	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
OO774_RS01085	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
OO774_RS01090	COG1053	succinate dehydrogenase
OO774_RS01095	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
OO774_RS01115	COG3385	transposase activity
OO774_RS01120	COG4942	peptidase
OO774_RS01125	COG1045	serine acetyltransferase
OO774_RS01130	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
OO774_RS01140	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OO774_RS01145	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
OO774_RS01155	COG3273	potassium ion transport
OO774_RS01155	COG0471	metal ion transport
OO774_RS01165	COG1162	GTPase activity
OO774_RS01170	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
OO774_RS01230	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
OO774_RS01235	COG0802	atpase or kinase
OO774_RS01240	COG0860	N-Acetylmuramoyl-L-alanine amidase
OO774_RS01245	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
OO774_RS01250	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
OO774_RS01260	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
OO774_RS01265	COG0330	HflC and HflK could
OO774_RS01270	COG0330	HflC and HflK could
OO774_RS01275	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
OO774_RS01280	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
OO774_RS01285	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
OO774_RS01290	COG1017	nitric oxide dioxygenase activity
OO774_RS01290	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OO774_RS01295	COG1959	2 iron, 2 sulfur cluster binding
OO774_RS01300	COG0557	exoribonuclease II activity
OO774_RS01305	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OO774_RS01310	COG0546	phosphoglycolate phosphatase activity
OO774_RS01315	COG0180	Tryptophanyl-tRNA synthetase
OO774_RS01320	COG0512	Glutamine amidotransferase of anthranilate synthase
OO774_RS01325	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
OO774_RS01335	COG1012	belongs to the aldehyde dehydrogenase family
OO774_RS01345	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OO774_RS01350	COG3954	Phosphoribulokinase
OO774_RS01360	COG0429	hydrolase of the alpha beta-hydrolase fold
OO774_RS01370	COG0488	(ABC) transporter
OO774_RS01375	COG2249	NAD(P)H dehydrogenase (quinone) activity
OO774_RS01390	COG1047	Peptidyl-prolyl cis-trans
OO774_RS01400	COG2900	Belongs to the SlyX family
OO774_RS01410	COG0545	Peptidyl-prolyl cis-trans isomerase
OO774_RS01415	COG2964	Protein conserved in bacteria
OO774_RS01420	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
OO774_RS01425	COG2923	Belongs to the DsrF TusC family
OO774_RS01445	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
OO774_RS01455	COG2906	2 iron, 2 sulfur cluster binding
OO774_RS01465	COG0281	malic enzyme
OO774_RS01475	COG0626	cystathionine gamma-synthase activity
OO774_RS01480	COG0527	aspartate kinase activity
OO774_RS01480	COG0460	homoserine dehydrogenase
OO774_RS01485	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
OO774_RS01495	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
OO774_RS01505	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
OO774_RS01510	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
OO774_RS01515	COG0137	argininosuccinate synthase activity
OO774_RS01520	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
OO774_RS01520	COG0165	Argininosuccinate lyase
OO774_RS01525	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
OO774_RS01525	COG0678	peroxiredoxin activity
OO774_RS01535	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
OO774_RS01565	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
OO774_RS01570	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
OO774_RS01580	COG0338	D12 class N6 adenine-specific DNA methyltransferase
OO774_RS01585	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
OO774_RS01590	COG0360	Binds together with S18 to 16S ribosomal RNA
OO774_RS01595	COG2965	DNA replication, synthesis of RNA primer
OO774_RS01620	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
OO774_RS01625	COG0432	Pfam Uncharacterised protein family UPF0047
OO774_RS01630	COG0166	Belongs to the GPI family
OO774_RS01640	COG0735	belongs to the Fur family
OO774_RS01645	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OO774_RS01665	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
OO774_RS01670	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OO774_RS01675	COG0175	sulfate reduction
OO774_RS01705	COG3385	transposase activity
OO774_RS01715	COG1410	methionine synthase
OO774_RS01715	COG0646	methionine synthase
OO774_RS01720	COG0527	aspartate kinase activity
OO774_RS01725	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
OO774_RS01735	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
OO774_RS01750	COG0629	single-stranded DNA binding
OO774_RS01755	COG2200	EAL domain
OO774_RS01755	COG2199	diguanylate cyclase activity
OO774_RS01780	COG3409	Peptidoglycan-binding domain 1 protein
OO774_RS01780	COG3267	Type II secretory pathway component ExeA
OO774_RS01790	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
OO774_RS01795	COG1459	type II secretion system
OO774_RS01805	COG2165	general secretion pathway protein
OO774_RS01840	COG1077	Cell shape determining protein MreB Mrl
OO774_RS01845	COG1792	Involved in formation and maintenance of cell shape
OO774_RS01850	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
OO774_RS01855	COG0424	maF-like protein
OO774_RS01870	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OO774_RS01875	COG0312	modulator of DNA gyrase
OO774_RS01880	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
OO774_RS01885	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
OO774_RS01895	COG0564	pseudouridine synthase activity
OO774_RS01900	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OO774_RS01905	COG3028	Belongs to the UPF0307 family
OO774_RS01910	COG0312	modulator of DNA gyrase
OO774_RS01915	COG2239	Acts as a magnesium transporter
OO774_RS01920	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
OO774_RS01925	COG1660	Displays ATPase and GTPase activities
OO774_RS01930	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
OO774_RS01935	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
OO774_RS01945	COG1137	ATPase activity
OO774_RS01950	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
OO774_RS01960	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
OO774_RS01960	COG0517	IMP dehydrogenase activity
OO774_RS01970	COG1127	ABC transporter
OO774_RS01975	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
OO774_RS01980	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
OO774_RS01985	COG2854	intermembrane phospholipid transfer
OO774_RS01995	COG5007	Belongs to the BolA IbaG family
OO774_RS02000	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OO774_RS02005	COG0204	Acyl-transferase
OO774_RS02010	COG0251	oxidation-reduction process
OO774_RS02015	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
OO774_RS02020	COG0540	Belongs to the ATCase OTCase family
OO774_RS02030	COG2235	arginine
OO774_RS02055	COG0525	valine-tRNA ligase activity
OO774_RS02060	COG2927	DNA polymerase III (CHI subunit)
OO774_RS02065	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
OO774_RS02070	COG0795	lipopolysaccharide-transporting ATPase activity
OO774_RS02075	COG0795	lipopolysaccharide-transporting ATPase activity
OO774_RS02090	COG1028	Short-chain dehydrogenase reductase Sdr
OO774_RS02105	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
OO774_RS02215	COG0741	lytic transglycosylase activity
OO774_RS02220	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
OO774_RS02240	COG2066	Belongs to the glutaminase family
OO774_RS02245	COG0635	Involved in the biosynthesis of porphyrin-containing compound
OO774_RS02250	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
OO774_RS02265	COG0762	integral membrane protein
OO774_RS02270	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
OO774_RS02275	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
OO774_RS02290	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
OO774_RS02295	COG1678	Uncharacterized ACR, COG1678
OO774_RS02300	COG0189	ligase activity
OO774_RS02305	COG1385	rRNA (uridine-N3-)-methyltransferase activity
OO774_RS02310	COG2356	endonuclease I
OO774_RS02325	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
OO774_RS02335	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
OO774_RS02345	COG0126	phosphoglycerate kinase activity
OO774_RS02350	COG0191	fructose-bisphosphate aldolase activity
OO774_RS02355	COG0668	transmembrane transport
OO774_RS02365	COG0583	DNA-binding transcription factor activity
OO774_RS02375	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
OO774_RS02380	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
OO774_RS02385	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
OO774_RS02395	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
OO774_RS02400	COG3079	Belongs to the UPF0149 family
OO774_RS02405	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OO774_RS02410	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OO774_RS02425	COG0354	folic acid binding
OO774_RS02430	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
OO774_RS02440	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
OO774_RS02445	COG1595	DNA-templated transcription, initiation
OO774_RS02460	COG3086	response to oxidative stress
OO774_RS02465	COG0481	GTPase activity
OO774_RS02480	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
OO774_RS02485	COG1381	Involved in DNA repair and RecF pathway recombination
OO774_RS02490	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
OO774_RS02495	COG0736	holo-[acyl-carrier-protein] synthase activity
OO774_RS02505	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OO774_RS02510	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OO774_RS02515	COG3956	TIGRFAM MazG family protein
OO774_RS02520	COG0504	CTP synthase activity
OO774_RS02525	COG0148	phosphopyruvate hydratase activity
OO774_RS02530	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
OO774_RS02535	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
OO774_RS02550	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
OO774_RS02555	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
OO774_RS02565	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OO774_RS02570	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
OO774_RS02575	COG1546	Belongs to the CinA family
OO774_RS02590	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
OO774_RS02595	COG0527	aspartate kinase activity
OO774_RS02685	COG3630	sodium ion export across plasma membrane
OO774_RS02690	COG5016	pyruvate
OO774_RS02690	COG0511	ligase activity, forming carbon-carbon bonds
OO774_RS02695	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
OO774_RS02705	COG1238	metal cluster binding
OO774_RS02710	COG0612	Peptidase, M16
OO774_RS02715	COG2918	glutathione biosynthetic process
OO774_RS02725	COG1854	S-ribosylhomocysteine lyase activity
OO774_RS02730	COG4536	flavin adenine dinucleotide binding
OO774_RS02735	COG4137	Cytochrome C assembly protein
OO774_RS02740	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
OO774_RS02745	COG0228	four-way junction DNA binding
OO774_RS02750	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
OO774_RS02765	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
OO774_RS02770	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
OO774_RS02775	COG0237	dephospho-CoA kinase activity
OO774_RS02785	COG1459	type II secretion system
OO774_RS02790	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
OO774_RS02800	COG0157	Belongs to the NadC ModD family
OO774_RS02810	COG2186	Transcriptional regulator
OO774_RS02815	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
OO774_RS02820	COG0508	dehydrogenase complex catalyzes the overall conversion of
OO774_RS02825	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OO774_RS02840	COG0583	DNA-binding transcription factor activity
OO774_RS02845	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
OO774_RS02850	COG3002	Belongs to the UPF0753 family
OO774_RS02855	COG0288	reversible hydration of carbon dioxide
OO774_RS02860	COG0659	secondary active sulfate transmembrane transporter activity
OO774_RS02865	COG1131	(ABC) transporter
OO774_RS02870	COG0842	Transport permease protein
OO774_RS02875	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
OO774_RS02880	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
OO774_RS02885	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
OO774_RS02895	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OO774_RS02905	COG1489	DNA binding
OO774_RS02910	COG1643	Atp-dependent helicase
OO774_RS02915	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OO774_RS02920	COG1752	Esterase of the alpha-beta hydrolase superfamily
OO774_RS02925	COG1049	propionate catabolic process, 2-methylcitrate cycle
OO774_RS02940	COG0004	ammonium transporteR
OO774_RS02945	COG1840	ABC-type Fe3 transport system, periplasmic component
OO774_RS02955	COG3842	ATPase activity
OO774_RS02960	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OO774_RS02975	COG2971	BadF BadG BcrA BcrD
OO774_RS02985	COG4608	Belongs to the ABC transporter superfamily
OO774_RS02990	COG0444	Belongs to the ABC transporter superfamily
OO774_RS02995	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OO774_RS03010	COG2205	protein histidine kinase activity
OO774_RS03010	COG0784	Response regulator, receiver
OO774_RS03015	COG2813	Specifically methylates the guanine in position
OO774_RS03020	COG0628	permease
OO774_RS03025	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
OO774_RS03030	COG0316	Belongs to the HesB IscA family
OO774_RS03035	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OO774_RS03040	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OO774_RS03045	COG0739	heme binding
OO774_RS03050	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
OO774_RS03055	COG2027	D-alanyl-D-alanine carboxypeptidase
OO774_RS03060	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
OO774_RS03065	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
OO774_RS03070	COG1534	Rna-binding protein
OO774_RS03075	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
OO774_RS03080	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OO774_RS03085	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
OO774_RS03095	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
OO774_RS03110	COG0779	Required for maturation of 30S ribosomal subunits
OO774_RS03115	COG0195	Participates in both transcription termination and antitermination
OO774_RS03120	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
OO774_RS03125	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
OO774_RS03130	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
OO774_RS03135	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
OO774_RS03140	COG1185	polyribonucleotide nucleotidyltransferase activity
OO774_RS03150	COG0826	peptidase U32
OO774_RS03155	COG0826	peptidase U32
OO774_RS03165	COG3154	lipid carrier protein
OO774_RS03170	COG3153	acetyltransferase
OO774_RS03190	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
OO774_RS03200	COG0084	hydrolase, TatD family'
OO774_RS03205	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
OO774_RS03210	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
OO774_RS03215	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
OO774_RS03220	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
OO774_RS03225	COG0813	purine-nucleoside phosphorylase activity
OO774_RS03235	COG0560	Phosphoserine phosphatase
OO774_RS03245	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
OO774_RS03250	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
OO774_RS03255	COG0583	DNA-binding transcription factor activity
OO774_RS03265	COG1022	Amp-dependent synthetase and ligase
OO774_RS03270	COG0741	lytic transglycosylase activity
OO774_RS03275	COG0583	DNA-binding transcription factor activity
OO774_RS03295	COG4964	Belongs to the GSP D family
OO774_RS03355	COG0583	DNA-binding transcription factor activity
OO774_RS03360	COG1609	Transcriptional regulator
OO774_RS03365	COG1609	Transcriptional regulator
OO774_RS03385	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
OO774_RS03390	COG1349	DNA-binding transcription factor activity
OO774_RS03395	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
OO774_RS03400	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
OO774_RS03405	COG2271	Major facilitator Superfamily
OO774_RS03410	COG2171	N-acyltransferase activity
OO774_RS03420	COG3141	response to X-ray
OO774_RS03430	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
OO774_RS03430	COG3264	Mechanosensitive ion channel
OO774_RS03435	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
OO774_RS03440	COG1074	ATP-dependent DNA helicase activity
OO774_RS03445	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
OO774_RS03455	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
OO774_RS03455	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
OO774_RS03465	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
OO774_RS03470	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
OO774_RS03475	COG2166	iron-sulfur cluster assembly
OO774_RS03480	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
OO774_RS03485	COG0693	protein deglycase activity
OO774_RS03490	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
OO774_RS03510	COG1595	DNA-templated transcription, initiation
OO774_RS03535	COG2813	Specifically methylates the guanine in position
OO774_RS03540	COG0271	Belongs to the BolA IbaG family
OO774_RS03545	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
OO774_RS03550	COG1805	sodium ion transport
OO774_RS03555	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
OO774_RS03560	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
OO774_RS03565	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
OO774_RS03570	COG2871	sodium ion transport
OO774_RS03575	COG1477	protein flavinylation
OO774_RS03580	COG2991	Protein conserved in bacteria
OO774_RS03590	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OO774_RS03595	COG0514	ATP-dependent DNA helicase (RecQ)
OO774_RS03600	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
OO774_RS03610	COG0733	neurotransmitter:sodium symporter activity
OO774_RS03630	COG1720	tRNA m6t6A37 methyltransferase activity
OO774_RS03635	COG0254	rRNA binding
OO774_RS03645	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
OO774_RS03680	COG0564	pseudouridine synthase activity
OO774_RS03690	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
OO774_RS03695	COG0024	Methionine aminopeptidase
OO774_RS03700	COG0052	Belongs to the universal ribosomal protein uS2 family
OO774_RS03710	COG0528	UMP kinase activity
OO774_RS03715	COG0233	cytoplasmic translational termination
OO774_RS03720	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
OO774_RS03725	COG0575	Belongs to the CDS family
OO774_RS03730	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
OO774_RS03735	COG0750	zinc metalloprotease
OO774_RS03745	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
OO774_RS03750	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OO774_RS03760	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OO774_RS03765	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OO774_RS03775	COG0587	DNA-directed DNA polymerase activity
OO774_RS03780	COG0825	malonyl-CoA metabolic process
OO774_RS03795	COG0347	Belongs to the P(II) protein family
OO774_RS03800	COG3021	interspecies interaction between organisms
OO774_RS03810	COG0741	lytic transglycosylase activity
OO774_RS03810	COG1388	LysM domain
OO774_RS03815	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OO774_RS03820	COG2226	methyltransferase
OO774_RS03825	COG0328	RNA-DNA hybrid ribonuclease activity
OO774_RS03845	COG1960	acyl-CoA dehydrogenase activity
OO774_RS03850	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
OO774_RS03855	COG0121	glutamine amidotransferase
OO774_RS03860	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
OO774_RS03865	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
OO774_RS03870	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
OO774_RS03875	COG2233	PERMEase
OO774_RS03895	COG1393	Belongs to the ArsC family
OO774_RS03900	COG4783	chaperone-mediated protein folding
OO774_RS03915	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
OO774_RS03920	COG2716	regulation of RNA biosynthetic process
OO774_RS03925	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OO774_RS03930	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
OO774_RS03950	COG1393	Belongs to the ArsC family
OO774_RS03975	COG2837	iron assimilation
OO774_RS03980	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
OO774_RS03985	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
OO774_RS03990	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
OO774_RS03995	COG1334	flagellar protein FlaG
OO774_RS04000	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
OO774_RS04010	COG1516	flagellar protein fliS
OO774_RS04030	COG1677	Flagellar hook-basal body complex protein FliE
OO774_RS04040	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
OO774_RS04090	COG1987	bacterial-type flagellum assembly
OO774_RS04130	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
OO774_RS04135	COG0643	Histidine kinase
OO774_RS04135	COG0784	Response regulator, receiver
OO774_RS04135	COG2198	Histidine kinase
OO774_RS04140	COG2201	protein-glutamate methylesterase activity
OO774_RS04145	COG1192	Involved in chromosome partitioning
OO774_RS04155	COG0835	chemotaxis
OO774_RS04165	COG4133	protoheme IX ABC transporter activity
OO774_RS04170	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
OO774_RS04175	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
OO774_RS04180	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
OO774_RS04185	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
OO774_RS04190	COG1138	Cytochrome C-type biogenesis protein
OO774_RS04195	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OO774_RS04220	COG2067	long-chain fatty acid transport protein
OO774_RS04235	COG0183	Belongs to the thiolase family
OO774_RS04240	COG1024	Enoyl-CoA hydratase
OO774_RS04240	COG1250	3-hydroxyacyl-CoA dehydrogenase
OO774_RS04250	COG2062	phosphohistidine phosphatase, SixA
OO774_RS04255	COG2840	Smr protein MutS2
OO774_RS04260	COG2890	protein-(glutamine-N5) methyltransferase activity
OO774_RS04265	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
OO774_RS04270	COG2860	membrane
OO774_RS04275	COG3101	peptidyl-lysine hydroxylation
OO774_RS04285	COG0431	NADPH-dependent FMN reductase
OO774_RS04290	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
OO774_RS04290	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OO774_RS04295	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
OO774_RS04305	COG1349	DNA-binding transcription factor activity
OO774_RS04315	COG4154	Belongs to the RbsD FucU family
OO774_RS04320	COG0235	Class ii aldolase
OO774_RS04325	COG0747	negative chemotaxis
OO774_RS04330	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
OO774_RS04335	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
OO774_RS04345	COG0101	tRNA pseudouridine synthase activity
OO774_RS04350	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
OO774_RS04355	COG0285	dihydrofolate synthase activity
OO774_RS04360	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
OO774_RS04365	COG1286	toxin biosynthetic process
OO774_RS04370	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
OO774_RS04375	COG5492	domain, Protein
OO774_RS04380	COG0583	DNA-binding transcription factor activity
OO774_RS04385	COG0745	RESPONSE REGULATOR receiver
OO774_RS04395	COG2832	Protein of unknown function (DUF454)
OO774_RS04400	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
OO774_RS04415	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
OO774_RS04420	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
OO774_RS04430	COG2261	transglycosylase associated protein
OO774_RS04435	COG2983	Belongs to the UPF0260 family
OO774_RS04440	COG0668	transmembrane transport
OO774_RS04455	COG2226	methyltransferase
OO774_RS04465	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
OO774_RS04470	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OO774_RS04480	COG3139	Protein of unknown function (DUF1315)
OO774_RS04485	COG0252	asparaginase activity
OO774_RS04490	COG0616	signal peptide processing
OO774_RS04495	COG0446	pyridine nucleotide-disulphide oxidoreductase
OO774_RS04495	COG1902	pentaerythritol trinitrate reductase activity
OO774_RS04500	COG0778	Nitroreductase
OO774_RS04505	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OO774_RS04520	COG0123	including yeast histone deacetylase and acetoin utilization protein
OO774_RS04525	COG1120	ATPase activity
OO774_RS04530	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OO774_RS04535	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OO774_RS04545	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
OO774_RS04555	COG3083	sulfuric ester hydrolase activity
OO774_RS04560	COG3082	Protein of unknown function (DUF1414)
OO774_RS04565	COG3081	Nucleoid-associated protein
OO774_RS04580	COG1757	Na H antiporter
OO774_RS04585	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
OO774_RS04590	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OO774_RS04595	COG2095	MarC family integral membrane protein
OO774_RS04600	COG1012	belongs to the aldehyde dehydrogenase family
OO774_RS04600	COG1454	alcohol dehydrogenase
OO774_RS04605	COG1028	Short-chain dehydrogenase reductase Sdr
OO774_RS04620	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
OO774_RS04630	COG0252	asparaginase activity
OO774_RS04655	COG2056	Na+-H+ antiporter family
OO774_RS04660	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
OO774_RS04665	COG2885	chlorophyll binding
OO774_RS04675	COG0346	lactoylglutathione lyase activity
OO774_RS04700	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
OO774_RS04705	COG4660	Part of a membrane complex involved in electron transport
OO774_RS04710	COG4659	FMN binding
OO774_RS04715	COG4658	electron transport chain
OO774_RS04720	COG4656	Part of a membrane complex involved in electron transport
OO774_RS04725	COG2878	Part of a membrane complex involved in electron transport
OO774_RS04730	COG4657	Part of a membrane complex involved in electron transport
OO774_RS04740	COG1121	(ABC) transporter
OO774_RS04745	COG1108	ABC-type Mn2 Zn2 transport systems permease components
OO774_RS04750	COG0523	cobalamin synthesis protein
OO774_RS04765	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
OO774_RS04775	COG0523	cobalamin synthesis protein
OO774_RS04855	COG4382	Mu-like prophage protein Gp16
OO774_RS04880	COG5566	PFAM Mor transcription activator
OO774_RS04910	COG0640	Transcriptional regulator
OO774_RS04925	COG4373	Mu-like prophage FluMu protein gp28
OO774_RS04930	COG4383	Mu-like prophage protein gp29
OO774_RS04965	COG4388	Caudovirus prohead serine protease
OO774_RS04975	COG4397	Mu-like prophage major head subunit gpT
OO774_RS04985	COG4387	Mu-like prophage protein GP36
OO774_RS05045	COG0556	nucleotide-excision repair
OO774_RS05050	COG2204	response regulator
OO774_RS05055	COG2198	Histidine kinase
OO774_RS05060	COG0391	Required for morphogenesis under gluconeogenic growth conditions
OO774_RS05065	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
OO774_RS05070	COG0521	Mo-molybdopterin cofactor biosynthetic process
OO774_RS05075	COG0315	cyclic pyranopterin monophosphate synthase activity
OO774_RS05080	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
OO774_RS05085	COG0314	molybdopterin synthase activity
OO774_RS05095	COG0601	transmembrane transport
OO774_RS05100	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OO774_RS05105	COG0444	Belongs to the ABC transporter superfamily
OO774_RS05115	COG0435	Glutathione S-transferase
OO774_RS05120	COG3174	membrane
OO774_RS05125	COG0280	phosphate acetyltransferase
OO774_RS05125	COG0857	belongs to the CobB CobQ family
OO774_RS05130	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
OO774_RS05135	COG3092	negative regulation of chromosome organization
OO774_RS05145	COG4120	Belongs to the binding-protein-dependent transport system permease family
OO774_RS05150	COG1122	ATPase activity
OO774_RS05155	COG0366	Alpha amylase catalytic
OO774_RS05160	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OO774_RS05165	COG0653	protein targeting
OO774_RS05170	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
OO774_RS05175	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
OO774_RS05180	COG2186	Transcriptional regulator
OO774_RS05190	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OO774_RS05190	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OO774_RS05195	COG0489	protein tyrosine kinase activity
OO774_RS05200	COG0572	uridine kinase
OO774_RS05210	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
OO774_RS05215	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OO774_RS05220	COG0659	secondary active sulfate transmembrane transporter activity
OO774_RS05225	COG1530	ribonuclease E activity
OO774_RS05230	COG0564	pseudouridine synthase activity
OO774_RS05235	COG0424	maF-like protein
OO774_RS05240	COG1399	metal-binding, possibly nucleic acid-binding protein
OO774_RS05245	COG0333	Belongs to the bacterial ribosomal protein bL32 family
OO774_RS05250	COG0416	fatty acid biosynthetic process
OO774_RS05255	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OO774_RS05285	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
OO774_RS05290	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
OO774_RS05295	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
OO774_RS05300	COG0084	hydrolase, TatD family'
OO774_RS05305	COG1263	PTS System
OO774_RS05305	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OO774_RS05305	COG2190	(PTS) system
OO774_RS05315	COG1263	PTS System
OO774_RS05315	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OO774_RS05330	COG0733	neurotransmitter:sodium symporter activity
OO774_RS05340	COG4667	esterase of the alpha-beta hydrolase superfamily
OO774_RS05345	COG0469	pyruvate kinase activity
OO774_RS05350	COG1940	carbohydrate kinase activity
OO774_RS05355	COG0587	DNA-directed DNA polymerase activity
OO774_RS05370	COG1028	Short-chain dehydrogenase reductase Sdr
OO774_RS05375	COG0616	signal peptide processing
OO774_RS05380	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
OO774_RS05385	COG0539	negative regulation of cytoplasmic translation
OO774_RS05395	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
OO774_RS05400	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
OO774_RS05410	COG4166	transmembrane transport
OO774_RS05420	COG0463	Glycosyl transferase, family 2
OO774_RS05430	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
OO774_RS05440	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
OO774_RS05440	COG3008	intermembrane lipid transfer
OO774_RS05445	COG2995	paraquat-inducible protein a
OO774_RS05450	COG3258	Cytochrome c
OO774_RS05455	COG2863	cytochrome
OO774_RS05490	COG2307	Protein conserved in bacteria
OO774_RS05490	COG2308	Evidence 4 Homologs of previously reported genes of
OO774_RS05505	COG2308	Evidence 4 Homologs of previously reported genes of
OO774_RS05510	COG3706	GGDEF domain
OO774_RS05520	COG0189	ligase activity
OO774_RS05530	COG3381	protein complex oligomerization
OO774_RS05535	COG0243	molybdopterin cofactor binding
OO774_RS05540	COG0437	4 iron, 4 sulfur cluster binding
OO774_RS05545	COG3302	dmso reductase anchor subunit
OO774_RS05550	COG1902	pentaerythritol trinitrate reductase activity
OO774_RS05560	COG4232	protein-disulfide reductase activity
OO774_RS05565	COG3118	belongs to the thioredoxin family
OO774_RS05595	COG5002	protein histidine kinase activity
OO774_RS05595	COG3850	Histidine kinase
OO774_RS05600	COG0745	RESPONSE REGULATOR receiver
OO774_RS05605	COG1032	radical SAM domain protein
OO774_RS05630	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
OO774_RS05640	COG2350	Protein conserved in bacteria
OO774_RS05665	COG1301	dicarboxylic acid transport
OO774_RS05670	COG0318	PFAM AMP-dependent synthetase and ligase
OO774_RS05675	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OO774_RS05680	COG0159	tryptophan synthase activity
OO774_RS05685	COG0133	tryptophan synthase activity
OO774_RS05690	COG0134	indole-3-glycerol-phosphate synthase activity
OO774_RS05690	COG0135	phosphoribosylanthranilate isomerase activity
OO774_RS05695	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
OO774_RS05700	COG0512	Glutamine amidotransferase of anthranilate synthase
OO774_RS05705	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
OO774_RS05715	COG0613	PHP domain protein
OO774_RS05720	COG0009	L-threonylcarbamoyladenylate synthase
OO774_RS05730	COG1187	pseudouridine synthase activity
OO774_RS05735	COG3099	Belongs to the UPF0263 family
OO774_RS05740	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
OO774_RS05750	COG0417	DNA replication proofreading
OO774_RS05755	COG2197	response regulator
OO774_RS05760	COG0322	excinuclease ABC activity
OO774_RS05800	COG0019	diaminopimelate decarboxylase activity
OO774_RS05830	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OO774_RS05835	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
OO774_RS05850	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
OO774_RS05875	COG2989	Protein conserved in bacteria
OO774_RS05880	COG3108	Peptidase M15
OO774_RS05885	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OO774_RS05900	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
OO774_RS05925	COG1846	Transcriptional regulator
OO774_RS05930	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OO774_RS05940	COG2176	DNA-directed DNA polymerase activity
OO774_RS05955	COG1448	Aminotransferase
OO774_RS05965	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OO774_RS05975	COG0017	Asparaginyl-tRNA synthetase
OO774_RS05980	COG0720	synthase
OO774_RS05985	COG1760	l-serine dehydratase
OO774_RS05990	COG0814	amino acid
OO774_RS06015	COG3106	COG3106 Predicted ATPase
OO774_RS06020	COG3768	UPF0283 membrane protein
OO774_RS06030	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OO774_RS06050	COG0582	viral genome integration into host DNA
OO774_RS06085	COG5532	Uncharacterized conserved protein (DUF2303)
OO774_RS06130	COG4626	Terminase
OO774_RS06130	COG1802	Transcriptional regulator
OO774_RS06150	COG1403	HNH endonuclease
OO774_RS06190	COG4220	transposase activity
OO774_RS06330	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
OO774_RS06335	COG2944	sequence-specific DNA binding
OO774_RS06385	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OO774_RS06480	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
OO774_RS06510	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
OO774_RS06515	COG2944	sequence-specific DNA binding
OO774_RS06525	COG0384	phenazine biosynthesis protein PhzF
OO774_RS06685	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
OO774_RS06700	COG2017	converts alpha-aldose to the beta-anomer
OO774_RS06705	COG1609	Transcriptional regulator
OO774_RS06710	COG1609	Transcriptional regulator
OO774_RS06715	COG3250	beta-galactosidase activity
OO774_RS06725	COG4580	involved in the transport of maltose and maltodextrins
OO774_RS06735	COG2211	Major facilitator Superfamily
OO774_RS06750	COG0738	Major facilitator superfamily
OO774_RS06760	COG1349	DNA-binding transcription factor activity
OO774_RS06765	COG0800	Aldolase
OO774_RS06880	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
OO774_RS06895	COG2017	converts alpha-aldose to the beta-anomer
OO774_RS06930	COG2186	Transcriptional regulator
OO774_RS06935	COG2731	YhcH YjgK YiaL family protein
OO774_RS06945	COG0840	transmembrane signaling receptor activity
OO774_RS06950	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
OO774_RS06955	COG1063	alcohol dehydrogenase
OO774_RS06960	COG0246	Mannitol dehydrogenase
OO774_RS06970	COG0800	Aldolase
OO774_RS06975	COG4948	Mandelate Racemase Muconate Lactonizing
OO774_RS07000	COG0534	Mate efflux family protein
OO774_RS07015	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OO774_RS07025	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OO774_RS07045	COG0148	phosphopyruvate hydratase activity
OO774_RS07075	COG0395	ABC-type sugar transport system, permease component
OO774_RS07080	COG1175	transmembrane transport
OO774_RS07095	COG2186	Transcriptional regulator
OO774_RS07100	COG1012	belongs to the aldehyde dehydrogenase family
OO774_RS07145	COG2814	Major facilitator Superfamily
OO774_RS07155	COG3250	beta-galactosidase activity
OO774_RS07165	COG4580	involved in the transport of maltose and maltodextrins
OO774_RS07185	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OO774_RS07195	COG1609	Transcriptional regulator
OO774_RS07205	COG1929	Belongs to the glycerate kinase type-1 family
OO774_RS07210	COG0383	alpha-mannosidase activity
OO774_RS07215	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OO774_RS07215	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OO774_RS07215	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
OO774_RS07220	COG2188	Transcriptional regulator
OO774_RS07280	COG1942	4-Oxalocrotonate Tautomerase
OO774_RS07390	COG2026	Addiction module toxin, RelE StbE family
OO774_RS07495	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
OO774_RS07510	COG0356	it plays a direct role in the translocation of protons across the membrane
OO774_RS07520	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
OO774_RS07520	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
OO774_RS07525	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
OO774_RS07535	COG1823	symporter activity
OO774_RS07540	COG0702	epimerase
OO774_RS07550	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
OO774_RS07570	COG2988	succinylglutamate desuccinylase activity
OO774_RS07575	COG4139	cobalamin transport
OO774_RS07600	COG0583	DNA-binding transcription factor activity
OO774_RS07610	COG1451	nucleotide metabolic process
OO774_RS07635	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
OO774_RS07640	COG4139	cobalamin transport
OO774_RS07655	COG2195	Cleaves the N-terminal amino acid of tripeptides
OO774_RS07665	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
OO774_RS07675	COG0625	glutathione transferase activity
OO774_RS07720	COG1278	Cold shock
OO774_RS07735	COG4974	Belongs to the 'phage' integrase family
OO774_RS07750	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OO774_RS07760	COG0583	DNA-binding transcription factor activity
OO774_RS07765	COG0006	proline dipeptidase activity
OO774_RS07785	COG4638	Rieske (2fe-2S)
OO774_RS07795	COG2113	Glycine betaine
OO774_RS07800	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OO774_RS07805	COG1012	belongs to the aldehyde dehydrogenase family
OO774_RS07820	COG0583	DNA-binding transcription factor activity
OO774_RS07825	COG4175	Glycine betaine
OO774_RS07830	COG4176	ABC-type proline glycine betaine transport system permease component
OO774_RS07835	COG1028	Short-chain dehydrogenase reductase Sdr
OO774_RS07840	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
OO774_RS07850	COG2207	Transcriptional regulator
OO774_RS07855	COG4145	pantothenate transmembrane transporter activity
OO774_RS07860	COG3924	membrane
OO774_RS07870	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
OO774_RS07890	COG0579	oxidoreductase
OO774_RS07920	COG1953	Uracil, thiamine, allantoin
OO774_RS07935	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
OO774_RS07950	COG2059	Chromate
OO774_RS07955	COG2059	Chromate
OO774_RS07985	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OO774_RS07995	COG1414	Transcriptional regulator
OO774_RS08000	COG0400	carboxylic ester hydrolase activity
OO774_RS08010	COG5002	protein histidine kinase activity
OO774_RS08010	COG2198	Histidine kinase
OO774_RS08010	COG0784	Response regulator, receiver
OO774_RS08020	COG0559	Belongs to the binding-protein-dependent transport system permease family
OO774_RS08040	COG0829	nickel cation binding
OO774_RS08045	COG0831	urea catabolic process
OO774_RS08050	COG0832	Belongs to the urease beta subunit family
OO774_RS08055	COG0804	urea catabolic process
OO774_RS08065	COG0830	nickel cation binding
OO774_RS08070	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
OO774_RS08080	COG0471	metal ion transport
OO774_RS08085	COG4191	Histidine kinase
OO774_RS08085	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OO774_RS08105	COG0814	amino acid
OO774_RS08125	COG1132	(ABC) transporter
OO774_RS08130	COG1132	(ABC) transporter
OO774_RS08145	COG0443	Heat shock 70 kDa protein
OO774_RS08150	COG0443	Heat shock 70 kDa protein
OO774_RS08185	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
OO774_RS08190	COG1643	Atp-dependent helicase
OO774_RS08205	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OO774_RS08215	COG1793	dna ligase
OO774_RS08225	COG0534	Mate efflux family protein
OO774_RS08230	COG0307	riboflavin synthase, alpha
OO774_RS08240	COG3001	Fructosamine kinase
OO774_RS08245	COG2201	protein-glutamate methylesterase activity
OO774_RS08250	COG3706	GGDEF domain
OO774_RS08260	COG0791	NLP P60 protein
OO774_RS08265	COG0840	transmembrane signaling receptor activity
OO774_RS08280	COG3148	PFAM DTW domain containing protein
OO774_RS08285	COG1940	carbohydrate kinase activity
OO774_RS08295	COG0303	'Molybdopterin
OO774_RS08305	COG3842	ATPase activity
OO774_RS08320	COG2204	response regulator
OO774_RS08325	COG4191	Histidine kinase
OO774_RS08330	COG0488	(ABC) transporter
OO774_RS08335	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
OO774_RS08365	COG0243	molybdopterin cofactor binding
OO774_RS08365	COG3383	formate dehydrogenase (NAD+) activity
OO774_RS08370	COG0437	4 iron, 4 sulfur cluster binding
OO774_RS08385	COG0110	maltose O-acetyltransferase activity
OO774_RS08390	COG2207	Transcriptional regulator
OO774_RS08395	COG0534	Mate efflux family protein
OO774_RS08400	COG0004	ammonium transporteR
OO774_RS08410	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
OO774_RS08415	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
OO774_RS08425	COG1177	transmembrane transport
OO774_RS08435	COG3842	ATPase activity
OO774_RS08455	COG0589	response to stress
OO774_RS08460	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OO774_RS08475	COG2217	Heavy metal translocating P-type atpase
OO774_RS08485	COG2010	Cytochrome c
OO774_RS08500	COG3278	Belongs to the heme-copper respiratory oxidase family
OO774_RS08520	COG2801	Transposase and inactivated derivatives
OO774_RS08555	COG1067	ATP-dependent peptidase activity
OO774_RS08560	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
OO774_RS08575	COG0488	(ABC) transporter
OO774_RS08585	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
OO774_RS08585	COG0116	Belongs to the methyltransferase superfamily
OO774_RS08595	COG0167	dihydroorotate dehydrogenase activity
OO774_RS08600	COG2902	Dehydrogenase
OO774_RS08610	COG0308	aminopeptidase N
OO774_RS08620	COG0793	Belongs to the peptidase S41A family
OO774_RS08625	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
OO774_RS08630	COG1956	GAF domain-containing protein
OO774_RS08635	COG1132	(ABC) transporter
OO774_RS08640	COG2995	paraquat-inducible protein a
OO774_RS08645	COG3008	intermembrane lipid transfer
OO774_RS08650	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
OO774_RS08650	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
OO774_RS08670	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
OO774_RS08675	COG1666	GTP binding
OO774_RS08685	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OO774_RS08690	COG4597	amino acid ABC transporter
OO774_RS08695	COG0765	amino acid transport
OO774_RS08700	COG1126	abc transporter atp-binding protein
OO774_RS08705	COG0670	Belongs to the BI1 family
OO774_RS08710	COG2920	part of a sulfur-relay system
OO774_RS08715	COG1254	Belongs to the acylphosphatase family
OO774_RS08720	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
OO774_RS08735	COG2885	chlorophyll binding
OO774_RS08745	COG3706	GGDEF domain
OO774_RS08755	COG0602	queuosine metabolic process
OO774_RS08760	COG0561	phosphatase activity
OO774_RS08765	COG0110	maltose O-acetyltransferase activity
OO774_RS08780	COG5001	Diguanylate cyclase
OO774_RS08815	COG2828	Protein conserved in bacteria
OO774_RS08825	COG0372	Belongs to the citrate synthase family
OO774_RS08830	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
OO774_RS08860	COG1012	belongs to the aldehyde dehydrogenase family
OO774_RS08865	COG3284	Transcriptional regulator
OO774_RS08880	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
OO774_RS08885	COG0363	glucosamine-6-phosphate deaminase activity
OO774_RS08890	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
OO774_RS08900	COG4774	siderophore transport
OO774_RS08905	COG4565	transcriptional regulatory protein
OO774_RS08910	COG3290	protein histidine kinase activity
OO774_RS08925	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OO774_RS08940	COG0527	aspartate kinase activity
OO774_RS08950	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
OO774_RS08955	COG0456	acetyltransferase
OO774_RS08965	COG4176	ABC-type proline glycine betaine transport system permease component
OO774_RS08970	COG2113	Glycine betaine
OO774_RS08990	COG4221	oxidoreductase activity
OO774_RS09000	COG0745	RESPONSE REGULATOR receiver
OO774_RS09005	COG0642	Histidine kinase
OO774_RS09010	COG1368	sulfuric ester hydrolase activity
OO774_RS09030	COG1115	amino acid carrier protein
OO774_RS09045	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OO774_RS09050	COG1280	lysine exporter protein (LysE YggA)
OO774_RS09055	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
OO774_RS09060	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
OO774_RS09070	COG1560	Kdo2-lipid A biosynthetic process
OO774_RS09080	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
OO774_RS09085	COG3063	Type IV pilus biogenesis stability protein PilW
OO774_RS09100	COG1846	Transcriptional regulator
OO774_RS09105	COG0697	spore germination
OO774_RS09110	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
OO774_RS09115	COG1012	belongs to the aldehyde dehydrogenase family
OO774_RS09120	COG2957	Belongs to the agmatine deiminase family
OO774_RS09130	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OO774_RS09135	COG1012	belongs to the aldehyde dehydrogenase family
OO774_RS09140	COG1396	sequence-specific DNA binding
OO774_RS09140	COG1917	Cupin 2, conserved barrel domain protein
OO774_RS09150	COG0174	glutamine synthetase
OO774_RS09155	COG1757	Na H antiporter
OO774_RS09180	COG3121	Chaperone
OO774_RS09205	COG2824	Alkylphosphonate utilization operon protein PhnA
OO774_RS09250	COG1794	racemase activity, acting on amino acids and derivatives
OO774_RS09270	COG0724	RNA recognition motif
OO774_RS09280	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
OO774_RS09285	COG1882	Formate acetyltransferase
OO774_RS09315	COG4656	Part of a membrane complex involved in electron transport
OO774_RS09320	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
OO774_RS09340	COG4820	ethanolamine utilization protein (EutJ)
OO774_RS09345	COG4869	propanediol catabolic process
OO774_RS09365	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
OO774_RS09370	COG2207	Transcriptional regulator
OO774_RS09375	COG2972	Histidine kinase
OO774_RS09385	COG0745	RESPONSE REGULATOR receiver
OO774_RS09390	COG5000	phosphorelay sensor kinase activity
OO774_RS09390	COG5002	protein histidine kinase activity
OO774_RS09420	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
OO774_RS09445	COG2925	Exonuclease
OO774_RS09450	COG1380	Effector of murein hydrolase LrgA
OO774_RS09455	COG1346	cytolysis
OO774_RS09460	COG0295	cytidine deaminase activity
OO774_RS09465	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
OO774_RS09480	COG0776	regulation of translation
OO774_RS09495	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OO774_RS09500	COG1621	beta-fructofuranosidase activity
OO774_RS09505	COG0072	phenylalanine-tRNA ligase activity
OO774_RS09505	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OO774_RS09510	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
OO774_RS09520	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
OO774_RS09535	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
OO774_RS09550	COG1228	amidohydrolase
OO774_RS09555	COG0010	Belongs to the arginase family
OO774_RS09565	COG3384	dioxygenase
OO774_RS09570	COG0583	DNA-binding transcription factor activity
OO774_RS09575	COG2020	methyltransferase activity
OO774_RS09580	COG0277	FAD linked oxidase domain protein
OO774_RS09580	COG0247	lactate metabolic process
OO774_RS09615	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
OO774_RS09630	COG0281	malic enzyme
OO774_RS09635	COG2949	membrane
OO774_RS09640	COG0471	metal ion transport
OO774_RS09660	COG0492	ferredoxin-NADP+ reductase activity
OO774_RS09665	COG4988	ABC transporter
OO774_RS09670	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
OO774_RS09680	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
OO774_RS09690	COG4191	Histidine kinase
OO774_RS09690	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OO774_RS09705	COG3070	regulator of competence-specific genes
OO774_RS09715	COG2431	L-lysine efflux transmembrane transporter activity
OO774_RS09725	COG0076	glutamate decarboxylase activity
OO774_RS09730	COG1737	Transcriptional regulator
OO774_RS09735	COG1012	belongs to the aldehyde dehydrogenase family
OO774_RS09735	COG1454	alcohol dehydrogenase
OO774_RS09740	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
OO774_RS09750	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
OO774_RS09765	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
OO774_RS09780	COG4181	ATPase activity
OO774_RS09785	COG0534	Mate efflux family protein
OO774_RS09790	COG0702	epimerase
OO774_RS09800	COG2814	Major facilitator Superfamily
OO774_RS09805	COG1187	pseudouridine synthase activity
OO774_RS09810	COG1061	Type III restriction enzyme res subunit
OO774_RS09825	COG0642	Histidine kinase
OO774_RS09830	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
OO774_RS09845	COG3313	Fe-S protein
OO774_RS09855	COG4134	Bacterial extracellular solute-binding protein
OO774_RS09860	COG4135	transport system, permease component
OO774_RS09865	COG4136	ATPase activity
OO774_RS09870	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
OO774_RS09880	COG3604	Transcriptional regulator
OO774_RS09885	COG1151	hydroxylamine reductase activity
OO774_RS09890	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OO774_RS09900	COG0564	pseudouridine synthase activity
OO774_RS09905	COG0733	neurotransmitter:sodium symporter activity
OO774_RS09915	COG0626	cystathionine gamma-synthase activity
OO774_RS09920	COG2818	Glycosylase
OO774_RS09940	COG1983	PspC domain protein
OO774_RS09950	COG1842	Phage shock protein A
OO774_RS09955	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
OO774_RS09975	COG4172	Belongs to the ABC transporter superfamily
OO774_RS09980	COG4172	Belongs to the ABC transporter superfamily
OO774_RS09990	COG1227	inorganic diphosphatase activity
OO774_RS10005	COG0243	molybdopterin cofactor binding
OO774_RS10010	COG3005	denitrification pathway
OO774_RS10015	COG4459	periplasmic nitrate reductase
OO774_RS10020	COG0390	transport system, permease component
OO774_RS10030	COG2116	formate transmembrane transporter activity
OO774_RS10045	COG1434	Gram-negative-bacterium-type cell wall biogenesis
OO774_RS10050	COG1435	thymidine kinase activity
OO774_RS10055	COG0215	cysteine-tRNA ligase activity
OO774_RS10060	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
OO774_RS10065	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OO774_RS10070	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
OO774_RS10075	COG3012	SEC-C Motif Domain Protein
OO774_RS10080	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
OO774_RS10080	COG0140	phosphoribosyl-ATP diphosphatase activity
OO774_RS10095	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
OO774_RS10100	COG0131	Imidazoleglycerol-phosphate dehydratase
OO774_RS10100	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
OO774_RS10105	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
OO774_RS10110	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
OO774_RS10115	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
OO774_RS10120	COG1757	Na H antiporter
OO774_RS10130	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OO774_RS10140	COG0482	sulfurtransferase activity
OO774_RS10150	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
OO774_RS10170	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
OO774_RS10185	COG4221	oxidoreductase activity
OO774_RS10195	COG0501	Belongs to the peptidase M48B family
OO774_RS10205	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
OO774_RS10215	COG0156	8-amino-7-oxononanoate synthase activity
OO774_RS10235	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
OO774_RS10240	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
OO774_RS10245	COG1674	ftsk spoiiie
OO774_RS10255	COG0686	Belongs to the AlaDH PNT family
OO774_RS10265	COG0583	DNA-binding transcription factor activity
OO774_RS10290	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OO774_RS10295	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OO774_RS10300	COG3135	benzoate transporter
OO774_RS10305	COG1396	sequence-specific DNA binding
OO774_RS10315	COG5001	Diguanylate cyclase
OO774_RS10315	COG5002	protein histidine kinase activity
OO774_RS10345	COG0784	Response regulator, receiver
OO774_RS10345	COG5002	protein histidine kinase activity
OO774_RS10365	COG1858	cytochrome C peroxidase
OO774_RS10380	COG0754	glutathionylspermidine amidase activity
OO774_RS10390	COG3766	membrane
OO774_RS10400	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
OO774_RS10405	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
OO774_RS10410	COG2885	chlorophyll binding
OO774_RS10415	COG0823	Involved in the tonB-independent uptake of proteins
OO774_RS10430	COG0811	peptide transport
OO774_RS10435	COG0824	Thioesterase
OO774_RS10445	COG4890	Cyd operon protein YbgT
OO774_RS10450	COG1294	oxidase, subunit
OO774_RS10455	COG1271	oxidase subunit
OO774_RS10460	COG2255	four-way junction helicase activity
OO774_RS10465	COG0632	four-way junction helicase activity
OO774_RS10470	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
OO774_RS10480	COG1801	Protein of unknown function DUF72
OO774_RS10490	COG0500	methyltransferase
OO774_RS10495	COG4067	protein conserved in archaea
OO774_RS10495	COG0189	ligase activity
OO774_RS10530	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
OO774_RS10535	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
OO774_RS10540	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
OO774_RS10545	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
OO774_RS10550	COG1434	Gram-negative-bacterium-type cell wall biogenesis
OO774_RS10555	COG0745	RESPONSE REGULATOR receiver
OO774_RS10560	COG3381	protein complex oligomerization
OO774_RS10565	COG1609	Transcriptional regulator
OO774_RS10570	COG3070	regulator of competence-specific genes
OO774_RS10590	COG0297	glycogen (starch) synthase activity
OO774_RS10595	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
OO774_RS10600	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OO774_RS10610	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
OO774_RS10620	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
OO774_RS10625	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
OO774_RS10630	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
OO774_RS10635	COG0542	response to heat
OO774_RS10640	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
OO774_RS10645	COG1278	Cold shock
OO774_RS10655	COG1187	pseudouridine synthase activity
OO774_RS10660	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
OO774_RS10670	COG1199	ATP-dependent helicase activity
OO774_RS10675	COG0730	response to heat
OO774_RS10680	COG3923	Primosomal replication protein n
OO774_RS10690	COG0708	Exodeoxyribonuclease III
OO774_RS10725	COG1882	Formate acetyltransferase
OO774_RS10730	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
OO774_RS10740	COG3013	Belongs to the UPF0304 family
OO774_RS10745	COG2766	serine protein kinase
OO774_RS10750	COG2718	Belongs to the UPF0229 family
OO774_RS10755	COG2719	SpoVR family
OO774_RS10760	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
OO774_RS10775	COG1132	(ABC) transporter
OO774_RS10780	COG0658	competence protein
OO774_RS10780	COG2333	competence protein COMEC
OO774_RS10790	COG4591	ABC-type transport system involved in lipoprotein release permease component
OO774_RS10795	COG1136	(ABC) transporter
OO774_RS10800	COG4591	ABC-type transport system involved in lipoprotein release permease component
OO774_RS10810	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
OO774_RS10825	COG1252	NADH dehydrogenase
OO774_RS10830	COG3150	esterase
OO774_RS10855	COG0537	adenosine 5'-monophosphoramidase activity
OO774_RS10880	COG0516	GMP reductase activity
OO774_RS10880	COG0517	IMP dehydrogenase activity
OO774_RS10885	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
OO774_RS10890	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
OO774_RS10895	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OO774_RS10905	COG1012	belongs to the aldehyde dehydrogenase family
OO774_RS10915	COG1177	transmembrane transport
OO774_RS10920	COG1176	ABC-type spermidine putrescine transport system, permease component I
OO774_RS10925	COG3842	ATPase activity
OO774_RS10930	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
OO774_RS10940	COG0174	glutamine synthetase
OO774_RS10945	COG0174	glutamine synthetase
OO774_RS10950	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OO774_RS10960	COG0439	Biotin carboxylase
OO774_RS10975	COG3842	ATPase activity
OO774_RS10980	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OO774_RS10995	COG0583	DNA-binding transcription factor activity
OO774_RS11015	COG3126	Type III secretion system lipoprotein chaperone (YscW)
OO774_RS11020	COG1946	Acyl-CoA thioesterase
OO774_RS11025	COG1522	sequence-specific DNA binding
OO774_RS11040	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OO774_RS11045	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OO774_RS11085	COG0477	Major facilitator Superfamily
OO774_RS11090	COG2855	membrane
OO774_RS11110	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
OO774_RS11115	COG0596	Alpha beta hydrolase
OO774_RS11120	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
OO774_RS11125	COG1169	isochorismate synthase
OO774_RS11130	COG0436	Aminotransferase
OO774_RS11135	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
OO774_RS11140	COG0232	Belongs to the dGTPase family. Type 2 subfamily
OO774_RS11155	COG1555	photosystem II stabilization
OO774_RS11160	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OO774_RS11165	COG0776	regulation of translation
OO774_RS11170	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
OO774_RS11175	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
OO774_RS11210	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
OO774_RS11215	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
OO774_RS11220	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
OO774_RS11225	COG3842	ATPase activity
OO774_RS11235	COG1175	transmembrane transport
OO774_RS11255	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
OO774_RS11260	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
OO774_RS11265	COG0569	domain protein
OO774_RS11270	COG0513	Belongs to the DEAD box helicase family
OO774_RS11275	COG1253	flavin adenine dinucleotide binding
OO774_RS11285	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OO774_RS11285	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OO774_RS11290	COG3433	isochorismatase activity
OO774_RS11290	COG1535	isochorismatase
OO774_RS11295	COG1021	2,3-dihydroxybenzoate-AMP ligase
OO774_RS11300	COG1169	isochorismate synthase
OO774_RS11310	COG1028	Short-chain dehydrogenase reductase Sdr
OO774_RS11320	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
OO774_RS11325	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
OO774_RS11330	COG0583	DNA-binding transcription factor activity
OO774_RS11335	COG2951	lytic endotransglycosylase activity
OO774_RS11350	COG2894	cell division
OO774_RS11355	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
OO774_RS11360	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
OO774_RS11365	COG0318	PFAM AMP-dependent synthetase and ligase
OO774_RS11370	COG2267	carboxylic ester hydrolase activity
OO774_RS11375	COG3065	identical protein binding
OO774_RS11385	COG1214	PFAM Peptidase M22, glycoprotease
OO774_RS11390	COG1199	ATP-dependent helicase activity
OO774_RS11395	COG0788	formyltetrahydrofolate deformylase activity
OO774_RS11410	COG3102	Protein conserved in bacteria
OO774_RS11415	COG0018	arginyl-trna synthetase
OO774_RS11435	COG1918	ferrous iron import across plasma membrane
OO774_RS11440	COG4977	sequence-specific DNA binding
OO774_RS11445	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
OO774_RS11450	COG1121	(ABC) transporter
OO774_RS11455	COG1108	ABC-type Mn2 Zn2 transport systems permease components
OO774_RS11465	COG0045	succinate-CoA ligase (ADP-forming) activity
OO774_RS11470	COG0508	dehydrogenase complex catalyzes the overall conversion of
OO774_RS11475	COG0567	Dehydrogenase, E1 component
OO774_RS11480	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
OO774_RS11485	COG1053	succinate dehydrogenase
OO774_RS11490	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
OO774_RS11505	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
OO774_RS11515	COG0033	Phosphoglucomutase
OO774_RS11520	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
OO774_RS11525	COG0596	Alpha beta hydrolase
OO774_RS11545	COG0735	belongs to the Fur family
OO774_RS11550	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OO774_RS11555	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OO774_RS11555	COG2190	(PTS) system
OO774_RS11555	COG1263	PTS System
OO774_RS11560	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
OO774_RS11565	COG1846	Transcriptional regulator
OO774_RS11565	COG1940	carbohydrate kinase activity
OO774_RS11570	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
OO774_RS11570	COG4651	solute:proton antiporter activity
OO774_RS11575	COG0367	asparagine synthase
OO774_RS11580	COG0250	Participates in transcription elongation, termination and antitermination
OO774_RS11585	COG3104	oligopeptide transport
OO774_RS11590	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
OO774_RS11600	COG0326	Molecular chaperone. Has ATPase activity
OO774_RS11605	COG3710	Transcriptional regulator
OO774_RS11625	COG0622	Phosphoesterase
OO774_RS11655	COG1090	epimerase
OO774_RS11660	COG0300	oxidoreductase activity
OO774_RS11665	COG3118	belongs to the thioredoxin family
OO774_RS11670	COG0330	HflC and HflK could
OO774_RS11695	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
OO774_RS11700	COG3115	cell septum assembly
OO774_RS11705	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
OO774_RS11710	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
OO774_RS11715	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
OO774_RS11720	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
OO774_RS11725	COG2190	(PTS) system
OO774_RS11730	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
OO774_RS11735	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
OO774_RS11745	COG3951	Flagellar rod assembly protein muramidase FlgJ
OO774_RS11745	COG1705	Flagellar rod assembly protein muramidase FlgJ
OO774_RS11750	COG1706	bacterial-type flagellum-dependent cell motility
OO774_RS11755	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
OO774_RS11765	COG4787	bacterial-type flagellum-dependent cell motility
OO774_RS11770	COG1749	Flagellar hook protein flgE
OO774_RS11785	COG1815	bacterial-type flagellum-dependent cell motility
OO774_RS11790	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
OO774_RS11795	COG0784	Response regulator, receiver
OO774_RS11795	COG0835	chemotaxis
OO774_RS11840	COG2885	chlorophyll binding
OO774_RS11840	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
OO774_RS11850	COG2217	Heavy metal translocating P-type atpase
OO774_RS11850	COG2608	mercury ion transmembrane transporter activity
OO774_RS11880	COG2840	Smr protein MutS2
OO774_RS11885	COG1187	pseudouridine synthase activity
OO774_RS11895	COG0737	Belongs to the 5'-nucleotidase family
OO774_RS11900	COG2877	3-deoxy-8-phosphooctulonate synthase activity
OO774_RS11905	COG2912	Transglutaminase-like superfamily
OO774_RS11910	COG3094	Invasion gene expression up-regulator, SirB
OO774_RS11915	COG2890	protein-(glutamine-N5) methyltransferase activity
OO774_RS11925	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
OO774_RS11930	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
OO774_RS11935	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
OO774_RS11940	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
OO774_RS11950	COG0012	GTP binding
OO774_RS12060	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OO774_RS12065	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
OO774_RS12070	COG1702	phosphate starvation-inducible protein PhoH
OO774_RS12080	COG4535	Mg2 and Co2 transporter CorC
OO774_RS12085	COG0815	Transfers the fatty acyl group on membrane lipoproteins
OO774_RS12090	COG2888	peptidyl-tyrosine sulfation
OO774_RS12100	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
OO774_RS12105	COG1466	dna polymerase III delta subunit
OO774_RS12110	COG0799	negative regulation of ribosome biogenesis
OO774_RS12120	COG0768	penicillin binding
OO774_RS12125	COG0772	Belongs to the SEDS family
OO774_RS12130	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
OO774_RS12135	COG1686	Belongs to the peptidase S11 family
OO774_RS12150	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
OO774_RS12155	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
OO774_RS12165	COG0366	Alpha amylase catalytic
OO774_RS12170	COG1263	PTS System
OO774_RS12170	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OO774_RS12180	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
OO774_RS12185	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
OO774_RS12190	COG2011	ABC-type metal ion transport system permease component
OO774_RS12195	COG1464	Belongs to the NlpA lipoprotein family
OO774_RS12200	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
OO774_RS12210	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
OO774_RS12210	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
OO774_RS12225	COG1611	Belongs to the LOG family
OO774_RS12230	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OO774_RS12240	COG2363	Small membrane protein
OO774_RS12250	COG0583	DNA-binding transcription factor activity
OO774_RS12255	COG0301	tRNA thio-modification
OO774_RS12255	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OO774_RS12260	COG2885	chlorophyll binding
OO774_RS12265	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
OO774_RS12275	COG0142	geranyltranstransferase activity
OO774_RS12280	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
OO774_RS12285	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
OO774_RS12290	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
OO774_RS12300	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
OO774_RS12320	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OO774_RS12320	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OO774_RS12325	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
OO774_RS12330	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
OO774_RS12335	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
OO774_RS12345	COG1073	alpha beta
OO774_RS12350	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
OO774_RS12355	COG2252	PERMEase
OO774_RS12360	COG2195	Cleaves the N-terminal amino acid of tripeptides
OO774_RS12395	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OO774_RS12395	COG0047	phosphoribosylformylglycinamidine synthase activity
OO774_RS12400	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
OO774_RS12415	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
OO774_RS12445	COG0484	heat shock protein binding
OO774_RS12460	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
OO774_RS12465	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
OO774_RS12470	COG0497	DNA recombination
OO774_RS12475	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OO774_RS12480	COG2914	Belongs to the UPF0125 (RnfH) family
OO774_RS12485	COG2867	negative regulation of translational initiation
OO774_RS12490	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
OO774_RS12510	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
OO774_RS12515	COG3716	PTS system mannose fructose sorbose family IID component
OO774_RS12525	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OO774_RS12530	COG2222	sugar isomerase
OO774_RS12540	COG1349	DNA-binding transcription factor activity
OO774_RS12545	COG2197	response regulator
OO774_RS12550	COG4585	Histidine kinase
OO774_RS12565	COG1404	Belongs to the peptidase S8 family
OO774_RS12580	COG3254	rhamnose metabolic process
OO774_RS12585	COG1070	Carbohydrate kinase
OO774_RS12590	COG4806	L-rhamnose isomerase
OO774_RS12595	COG0235	Class ii aldolase
OO774_RS12600	COG0583	DNA-binding transcription factor activity
OO774_RS12605	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OO774_RS12605	COG3153	acetyltransferase
OO774_RS12625	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
OO774_RS12630	COG2873	o-acetylhomoserine
OO774_RS12640	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OO774_RS12645	COG1115	amino acid carrier protein
OO774_RS12655	COG1473	amidohydrolase
OO774_RS12670	COG1584	GPR1 FUN34 yaaH family protein
OO774_RS12680	COG3345	alpha-galactosidase
OO774_RS12685	COG0519	Catalyzes the synthesis of GMP from XMP
OO774_RS12685	COG0518	GMP synthase (glutamine-hydrolyzing) activity
OO774_RS12690	COG0516	GMP reductase activity
OO774_RS12690	COG0517	IMP dehydrogenase activity
OO774_RS12710	COG1160	GTP binding
OO774_RS12715	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OO774_RS12720	COG2976	Protein conserved in bacteria
OO774_RS12725	COG0124	histidyl-tRNA synthetase
OO774_RS12730	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
OO774_RS12745	COG0105	UTP biosynthetic process
OO774_RS12750	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
OO774_RS12755	COG2975	iron-sulfur cluster assembly
OO774_RS12760	COG0633	Ferredoxin
OO774_RS12765	COG0443	Heat shock 70 kDa protein
OO774_RS12770	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
OO774_RS12775	COG0316	Belongs to the HesB IscA family
OO774_RS12780	COG0822	iron-sulfur transferase activity
OO774_RS12785	COG1104	cysteine desulfurase activity
OO774_RS12795	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
OO774_RS12800	COG0483	inositol monophosphate 1-phosphatase activity
OO774_RS12805	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OO774_RS12810	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OO774_RS12815	COG1862	Preprotein translocase
OO774_RS12820	COG0343	queuine tRNA-ribosyltransferase activity
OO774_RS12825	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
OO774_RS12830	COG0517	IMP dehydrogenase activity
OO774_RS12840	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
OO774_RS12845	COG0583	DNA-binding transcription factor activity
OO774_RS12850	COG0450	alkyl hydroperoxide reductase
OO774_RS12855	COG3142	Participates in the control of copper homeostasis
OO774_RS12880	COG0418	dihydroorotase activity
OO774_RS12885	COG0167	dihydroorotate dehydrogenase activity
OO774_RS12900	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OO774_RS12905	COG1914	H( )-stimulated, divalent metal cation uptake system
OO774_RS12910	COG0704	Plays a role in the regulation of phosphate uptake
OO774_RS12915	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
OO774_RS12920	COG0581	inorganic phosphate transmembrane transporter activity
OO774_RS12925	COG0573	inorganic phosphate transmembrane transporter activity
OO774_RS12930	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
OO774_RS12935	COG0248	Ppx GppA phosphatase
OO774_RS12945	COG5002	protein histidine kinase activity
OO774_RS12950	COG0745	RESPONSE REGULATOR receiver
OO774_RS12955	COG2974	May be involved in recombination
OO774_RS12960	COG0826	peptidase U32
OO774_RS12965	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
OO774_RS13025	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OO774_RS13030	COG1116	anion transmembrane transporter activity
OO774_RS13045	COG0542	response to heat
OO774_RS13055	COG0564	pseudouridine synthase activity
OO774_RS13060	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OO774_RS13065	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
OO774_RS13070	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
OO774_RS13075	COG0077	Prephenate dehydratase
OO774_RS13075	COG1605	Chorismate mutase
OO774_RS13080	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
OO774_RS13095	COG0488	(ABC) transporter
OO774_RS13100	COG0739	heme binding
OO774_RS13105	COG0287	Prephenate dehydrogenase
OO774_RS13105	COG1605	Chorismate mutase
OO774_RS13110	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
OO774_RS13115	COG1472	Belongs to the glycosyl hydrolase 3 family
OO774_RS13120	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
OO774_RS13140	COG1966	Carbon starvation protein
OO774_RS13145	COG3275	phosphorelay sensor kinase activity
OO774_RS13150	COG3279	Response regulator of the LytR AlgR family
OO774_RS13155	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
OO774_RS13160	COG1047	Peptidyl-prolyl cis-trans
OO774_RS13165	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
OO774_RS13170	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
OO774_RS13175	COG0196	riboflavin kinase activity
OO774_RS13180	COG0728	peptidoglycan biosynthetic process
OO774_RS13185	COG0268	Binds directly to 16S ribosomal RNA
OO774_RS13190	COG0640	Transcriptional regulator
OO774_RS13195	COG0583	DNA-binding transcription factor activity
OO774_RS13200	COG1283	sodium-dependent phosphate transmembrane transporter activity
OO774_RS13210	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
OO774_RS13215	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
OO774_RS13220	COG0730	response to heat
OO774_RS13235	COG3066	DNA modification
OO774_RS13245	COG0667	Aldo Keto reductase
OO774_RS13255	COG3290	protein histidine kinase activity
OO774_RS13255	COG3829	transcription factor binding
OO774_RS13260	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
OO774_RS13270	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
OO774_RS13275	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
OO774_RS13280	COG4974	Belongs to the 'phage' integrase family
OO774_RS13295	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
OO774_RS13300	COG0513	Belongs to the DEAD box helicase family
OO774_RS13305	COG3022	response to hydroperoxide
OO774_RS13310	COG1115	amino acid carrier protein
OO774_RS13325	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
OO774_RS13330	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
OO774_RS13335	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
OO774_RS13340	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
OO774_RS13345	COG0083	homoserine kinase activity
OO774_RS13360	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
OO774_RS13370	COG0745	RESPONSE REGULATOR receiver
OO774_RS13380	COG2198	Histidine kinase
OO774_RS13380	COG0784	Response regulator, receiver
OO774_RS13380	COG5002	protein histidine kinase activity
OO774_RS13385	COG1242	4 iron, 4 sulfur cluster binding
OO774_RS13390	COG0067	glutamate synthase
OO774_RS13390	COG0069	glutamate synthase activity
OO774_RS13390	COG0070	glutamate synthase
OO774_RS13400	COG0067	glutamate synthase
OO774_RS13400	COG0069	glutamate synthase activity
OO774_RS13400	COG0070	glutamate synthase
OO774_RS13405	COG0493	'glutamate synthase
OO774_RS13415	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
OO774_RS13425	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
OO774_RS13430	COG2860	membrane
OO774_RS13435	COG0730	response to heat
OO774_RS13440	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
OO774_RS13445	COG0505	Belongs to the CarA family
OO774_RS13455	COG0494	nUDIX hydrolase
OO774_RS13460	COG0653	protein targeting
OO774_RS13470	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
OO774_RS13475	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
OO774_RS13480	COG0849	cell division
OO774_RS13485	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
OO774_RS13495	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
OO774_RS13500	COG0772	Belongs to the SEDS family
OO774_RS13505	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
OO774_RS13510	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
OO774_RS13515	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
OO774_RS13520	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
OO774_RS13525	COG0768	penicillin binding
OO774_RS13530	COG3116	cell division
OO774_RS13535	COG0275	rRNA processing
OO774_RS13545	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
OO774_RS13560	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
OO774_RS13565	COG2823	Periplasmic or secreted lipoprotein
OO774_RS13570	COG2969	positive regulation of protein catabolic process
OO774_RS13575	COG0625	glutathione transferase activity
OO774_RS13580	COG2857	Cytochrome c1
OO774_RS13585	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
OO774_RS13590	COG0723	plastoquinol--plastocyanin reductase activity
OO774_RS13595	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
OO774_RS13605	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
OO774_RS13610	COG3105	Protein conserved in bacteria
OO774_RS13620	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OO774_RS13625	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
OO774_RS13635	COG3150	esterase
OO774_RS13645	COG3151	Protein conserved in bacteria
OO774_RS13650	COG0494	nUDIX hydrolase
OO774_RS13655	COG1538	Outer membrane efflux protein
OO774_RS13665	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
OO774_RS13680	COG3025	triphosphatase activity
OO774_RS13685	COG1392	Phosphate transport regulator
OO774_RS13690	COG0306	phosphate transporter
OO774_RS13695	COG4991	sh3 domain protein
OO774_RS13705	COG3409	Peptidoglycan-binding domain 1 protein
OO774_RS13705	COG3267	Type II secretory pathway component ExeA
OO774_RS13710	COG0617	tRNA 3'-terminal CCA addition
OO774_RS13715	COG1968	undecaprenyl-diphosphatase activity
OO774_RS13720	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
OO774_RS13725	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
OO774_RS13730	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
OO774_RS13735	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OO774_RS13740	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
OO774_RS13745	COG0828	Belongs to the bacterial ribosomal protein bS21 family
OO774_RS13750	COG1610	YqeY-like protein
OO774_RS13755	COG0358	DNA primase activity
OO774_RS13775	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
OO774_RS13780	COG1464	Belongs to the NlpA lipoprotein family
OO774_RS13800	COG2213	PTS system mannitol-specific
OO774_RS13800	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
OO774_RS13810	COG3722	fumarate hydratase activity
OO774_RS13815	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
OO774_RS13820	COG1263	PTS System
OO774_RS13820	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OO774_RS13830	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
OO774_RS13835	COG1349	DNA-binding transcription factor activity
OO774_RS13840	COG0469	pyruvate kinase activity
OO774_RS13845	COG0440	acetolactate synthase activity
OO774_RS13850	COG0028	Belongs to the TPP enzyme family
OO774_RS13855	COG1022	Amp-dependent synthetase and ligase
OO774_RS13860	COG0583	DNA-binding transcription factor activity
OO774_RS13870	COG0671	phosphoesterase, PA-phosphatase related
OO774_RS13880	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OO774_RS13885	COG0473	3-isopropylmalate dehydrogenase activity
OO774_RS13895	COG0066	3-isopropylmalate dehydratase activity
OO774_RS13905	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
OO774_RS13910	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
OO774_RS13915	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OO774_RS13920	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
OO774_RS13925	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
OO774_RS13930	COG2967	ApaG domain
OO774_RS13940	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
OO774_RS13950	COG2966	Psort location CytoplasmicMembrane, score
OO774_RS13955	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
OO774_RS13965	COG0261	This protein binds to 23S rRNA in the presence of protein L20
OO774_RS13970	COG0142	geranyltranstransferase activity
OO774_RS13980	COG0039	L-malate dehydrogenase activity
OO774_RS14005	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
OO774_RS14010	COG1178	ABC-type Fe3 transport system permease component
OO774_RS14015	COG4143	(ABC) transporter
OO774_RS14020	COG0163	prenyltransferase activity
OO774_RS14025	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
OO774_RS14030	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
OO774_RS14035	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
OO774_RS14040	COG2105	PFAM AIG2 family protein
OO774_RS14045	COG2911	Protein conserved in bacteria
OO774_RS14055	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OO774_RS14065	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
OO774_RS14100	COG0529	Catalyzes the synthesis of activated sulfate
OO774_RS14105	COG0471	metal ion transport
OO774_RS14105	COG3273	potassium ion transport
OO774_RS14115	COG0175	sulfate reduction
OO774_RS14120	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
OO774_RS14120	COG1648	precorrin-2 dehydrogenase activity
OO774_RS14125	COG0513	Belongs to the DEAD box helicase family
OO774_RS14130	COG2153	protein acetylation
OO774_RS14140	COG0545	Peptidyl-prolyl cis-trans isomerase
OO774_RS14150	COG0203	ribosomal protein L17
OO774_RS14155	COG0202	RNA polymerase activity
OO774_RS14165	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
OO774_RS14170	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
OO774_RS14175	COG0257	Belongs to the bacterial ribosomal protein bL36 family
OO774_RS14180	COG0201	protein transport
OO774_RS14185	COG0200	Binds to the 23S rRNA
OO774_RS14190	COG1841	ribosomal large subunit assembly
OO774_RS14220	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
OO774_RS14225	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
OO774_RS14235	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
OO774_RS14240	COG0255	Belongs to the universal ribosomal protein uL29 family
OO774_RS14250	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
OO774_RS14255	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
OO774_RS14260	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
OO774_RS14265	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
OO774_RS14275	COG0088	Forms part of the polypeptide exit tunnel
OO774_RS14280	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
OO774_RS14290	COG0254	rRNA binding
OO774_RS14295	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
OO774_RS14300	COG1609	Transcriptional regulator
OO774_RS14315	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
OO774_RS14320	COG1575	Belongs to the MenA family. Type 1 subfamily
OO774_RS14325	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
OO774_RS14335	COG1494	fructose-1,6-bisphosphatase
OO774_RS14350	COG3152	Membrane
OO774_RS14365	COG0149	triose-phosphate isomerase activity
OO774_RS14375	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
OO774_RS14390	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
OO774_RS14400	COG0438	transferase activity, transferring glycosyl groups
OO774_RS14430	COG1215	transferase activity, transferring glycosyl groups
OO774_RS14450	COG0489	protein tyrosine kinase activity
OO774_RS14450	COG3206	protein involved in exopolysaccharide biosynthesis
OO774_RS14465	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
OO774_RS14470	COG1215	transferase activity, transferring glycosyl groups
OO774_RS14480	COG0463	Glycosyl transferase, family 2
OO774_RS14500	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
OO774_RS14505	COG2244	polysaccharide biosynthetic process
OO774_RS14510	COG2895	sulfate adenylyltransferase (ATP) activity
OO774_RS14515	COG0529	Catalyzes the synthesis of activated sulfate
OO774_RS14520	COG0471	metal ion transport
OO774_RS14520	COG3273	potassium ion transport
OO774_RS14525	COG0175	sulfate reduction
OO774_RS14565	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OO774_RS14575	COG1560	Kdo2-lipid A biosynthetic process
OO774_RS14580	COG0859	PFAM glycosyl transferase family 9
OO774_RS14585	COG1519	Transferase
OO774_RS14600	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
OO774_RS14605	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
OO774_RS14625	COG3642	lipopolysaccharide core region biosynthetic process
OO774_RS14630	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
OO774_RS14635	COG0438	transferase activity, transferring glycosyl groups
OO774_RS14645	COG0859	PFAM glycosyl transferase family 9
OO774_RS14650	COG0438	transferase activity, transferring glycosyl groups
OO774_RS14655	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
OO774_RS14660	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
OO774_RS14680	COG2003	Belongs to the UPF0758 family
OO774_RS14690	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
OO774_RS14695	COG1309	transcriptional regulator
OO774_RS14700	COG1560	Kdo2-lipid A biosynthetic process
OO774_RS14705	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
OO774_RS14710	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
OO774_RS14715	COG1561	YicC-like family, N-terminal region
OO774_RS14730	COG0251	oxidation-reduction process
OO774_RS14735	COG0814	amino acid
OO774_RS14740	COG3033	Beta-eliminating lyase
OO774_RS14760	COG4608	Belongs to the ABC transporter superfamily
OO774_RS14765	COG0444	Belongs to the ABC transporter superfamily
OO774_RS14770	COG0747	negative chemotaxis
OO774_RS14775	COG4239	(ABC) transporter, permease
OO774_RS14780	COG4174	ABC transporter (Permease)
OO774_RS14800	COG0811	peptide transport
OO774_RS14805	COG0848	biopolymer transport protein
OO774_RS14820	COG0194	GDP metabolic process
OO774_RS14825	COG1758	RNA polymerase activity
OO774_RS14830	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OO774_RS14835	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OO774_RS14840	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
OO774_RS14845	COG2233	PERMEase
OO774_RS14865	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
OO774_RS14875	COG2183	response to ionizing radiation
OO774_RS14885	COG0596	Alpha beta hydrolase
OO774_RS14890	COG1040	competence protein
OO774_RS14900	COG0494	nUDIX hydrolase
OO774_RS14905	COG1218	3'(2'),5'-bisphosphate nucleotidase
OO774_RS14915	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
OO774_RS14920	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
OO774_RS14925	COG3156	type II secretion system protein K
OO774_RS14930	COG4795	General secretion pathway protein
OO774_RS14935	COG2165	general secretion pathway protein
OO774_RS14940	COG2165	general secretion pathway protein
OO774_RS14945	COG2165	general secretion pathway protein
OO774_RS14950	COG1459	type II secretion system
OO774_RS14955	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
OO774_RS14965	COG3031	protein transport across the cell outer membrane
OO774_RS14970	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
OO774_RS14975	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
OO774_RS14980	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
OO774_RS14990	COG0456	acetyltransferase
OO774_RS14995	COG1490	D-aminoacyl-tRNA deacylase activity
OO774_RS15000	COG1295	ribonuclease BN
OO774_RS15015	COG1217	gtp-binding protein TYPA
OO774_RS15020	COG0174	glutamine synthetase
OO774_RS15030	COG3852	Histidine kinase
OO774_RS15035	COG2204	response regulator
OO774_RS15045	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
OO774_RS15075	COG0218	Necessary for normal cell division and for the maintenance of normal septation
OO774_RS15080	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OO774_RS15080	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OO774_RS15095	COG0084	hydrolase, TatD family'
OO774_RS15100	COG0805	protein transport
OO774_RS15105	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OO774_RS15115	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
OO774_RS15120	COG3165	ubiquinone biosynthetic process from chorismate
OO774_RS15125	COG2226	methyltransferase
OO774_RS15130	COG1322	Protein conserved in bacteria
OO774_RS15145	COG2081	HI0933 family
OO774_RS15155	COG1528	Iron-storage protein
OO774_RS15160	COG0589	response to stress
OO774_RS15175	COG0742	ribosomal rna small subunit methyltransferase
OO774_RS15180	COG1522	sequence-specific DNA binding
OO774_RS15185	COG0339	signal peptide processing
OO774_RS15190	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
OO774_RS15195	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OO774_RS15205	COG0748	coenzyme F420 binding
OO774_RS15210	COG3721	Heme iron utilization protein
OO774_RS15215	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
OO774_RS15220	COG0811	peptide transport
OO774_RS15225	COG0848	biopolymer transport protein
OO774_RS15235	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OO774_RS15240	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
OO774_RS15245	COG0800	Aldolase
OO774_RS15250	COG2610	gluconate transmembrane transporter activity
OO774_RS15255	COG3265	gluconokinase activity
OO774_RS15260	COG0129	dihydroxy-acid dehydratase activity
OO774_RS15265	COG1609	Transcriptional regulator
OO774_RS15270	COG0515	serine threonine protein kinase
OO774_RS15270	COG2815	serine threonine protein kinase
OO774_RS15300	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OO774_RS15305	COG0601	transmembrane transport
OO774_RS15310	COG4166	transmembrane transport
OO774_RS15360	COG1309	transcriptional regulator
OO774_RS15365	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OO774_RS15370	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OO774_RS15375	COG2960	long-chain fatty acid transporting porin activity
OO774_RS15380	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
OO774_RS15385	COG0583	DNA-binding transcription factor activity
OO774_RS15390	COG0745	RESPONSE REGULATOR receiver
OO774_RS15395	COG2205	protein histidine kinase activity
OO774_RS15400	COG1263	PTS System
OO774_RS15400	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OO774_RS15435	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
OO774_RS15445	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
OO774_RS15450	COG0408	coproporphyrinogen oxidase activity
OO774_RS15455	COG0009	L-threonylcarbamoyladenylate synthase
OO774_RS15460	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
OO774_RS15465	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
OO774_RS15470	COG0551	DNA topoisomerase type I activity
OO774_RS15475	COG2922	Belongs to the Smg family
OO774_RS15480	COG0758	DNA mediated transformation
OO774_RS15495	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
OO774_RS15500	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
OO774_RS15500	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
OO774_RS15505	COG0569	domain protein
OO774_RS15510	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
OO774_RS15520	COG1272	protein, Hemolysin III
OO774_RS15525	COG4326	sporulation control protein
OO774_RS15535	COG3084	Protein conserved in bacteria
OO774_RS15545	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
OO774_RS15550	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
OO774_RS15555	COG0204	Acyl-transferase
OO774_RS15565	COG0606	chelatase, subunit chli
OO774_RS15575	COG3978	acetolactate synthase activity
OO774_RS15590	COG0583	DNA-binding transcription factor activity
OO774_RS15595	COG2814	Major facilitator Superfamily
OO774_RS15605	COG0355	proton-transporting ATP synthase activity, rotational mechanism
OO774_RS15610	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
OO774_RS15615	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
OO774_RS15620	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
OO774_RS15625	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
OO774_RS15630	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
OO774_RS15640	COG0356	it plays a direct role in the translocation of protons across the membrane
OO774_RS15645	COG3312	ion transport
OO774_RS15650	COG1475	DNA binding
OO774_RS15655	COG1192	Involved in chromosome partitioning
OO774_RS15665	COG0445	tRNA wobble uridine modification
OO774_RS15670	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
OO774_RS15680	COG0706	membrane insertase activity
OO774_RS15690	COG0594	ribonuclease P activity
OO774_RS15700	COG1126	abc transporter atp-binding protein
OO774_RS15715	COG2207	Transcriptional regulator
OO774_RS15725	COG3530	Putative quorum-sensing-regulated virulence factor
OO774_RS15750	COG3186	Phenylalanine-4-hydroxylase
OO774_RS15755	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OO774_RS15760	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
OO774_RS15775	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
OO774_RS15780	COG1454	alcohol dehydrogenase
OO774_RS15785	COG2133	pyrroloquinoline quinone binding
OO774_RS15795	COG0783	Belongs to the Dps family
OO774_RS15805	COG1136	(ABC) transporter
OO774_RS15830	COG1278	Cold shock
OO774_RS15860	COG0545	Peptidyl-prolyl cis-trans isomerase
OO774_RS15865	COG0109	protoheme IX farnesyltransferase activity
OO774_RS15870	COG1612	heme a metabolic process
OO774_RS15895	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
OO774_RS15900	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OO774_RS15910	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OO774_RS15915	COG1280	lysine exporter protein (LysE YggA)
OO774_RS15930	COG0179	Fumarylacetoacetate (FAA) hydrolase
OO774_RS15960	COG0739	heme binding
OO774_RS15980	COG3314	Sporulation integral membrane protein YlbJ
OO774_RS16000	COG0814	amino acid
OO774_RS16020	COG0798	PFAM Bile acid sodium symporter
OO774_RS16030	COG1131	(ABC) transporter
OO774_RS16035	COG0842	Transport permease protein
OO774_RS16045	COG3383	formate dehydrogenase (NAD+) activity
OO774_RS16065	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OO774_RS16090	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OO774_RS16095	COG0589	response to stress
OO774_RS16105	COG2731	YhcH YjgK YiaL family protein
OO774_RS16120	COG2358	TRAP transporter, solute receptor (TAXI family
OO774_RS16125	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OO774_RS16130	COG1454	alcohol dehydrogenase
OO774_RS16135	COG3395	kinase activity
OO774_RS16140	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
OO774_RS16145	COG1349	DNA-binding transcription factor activity
OO774_RS16155	COG0366	Alpha amylase catalytic
OO774_RS16170	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
OO774_RS16180	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
OO774_RS16190	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
OO774_RS16215	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
OO774_RS16225	COG4948	Mandelate Racemase Muconate Lactonizing
OO774_RS16245	COG1902	pentaerythritol trinitrate reductase activity
OO774_RS16260	COG0583	DNA-binding transcription factor activity
OO774_RS16265	COG1063	alcohol dehydrogenase
OO774_RS16280	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
OO774_RS16290	COG0583	DNA-binding transcription factor activity
OO774_RS16295	COG4771	TonB-dependent receptor
OO774_RS16310	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OO774_RS16315	COG0784	Response regulator, receiver
OO774_RS16315	COG0835	chemotaxis
OO774_RS16350	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
OO774_RS16355	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
OO774_RS16360	COG0633	Ferredoxin
OO774_RS16360	COG3217	Mosc domain protein beta barrel domain protein
OO774_RS16360	COG0633	Ferredoxin
OO774_RS16360	COG3217	Mosc domain protein beta barrel domain protein
OO774_RS16370	COG0418	dihydroorotase activity
OO774_RS16375	COG2354	Protein conserved in bacteria
OO774_RS16385	COG2176	DNA-directed DNA polymerase activity
OO774_RS16400	COG2188	Transcriptional regulator
OO774_RS16430	COG1011	Hydrolase
OO774_RS16445	COG0450	alkyl hydroperoxide reductase
OO774_RS16475	COG1028	Short-chain dehydrogenase reductase Sdr
OO774_RS16485	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OO774_RS16490	COG4605	iron ion homeostasis
OO774_RS16495	COG4607	ABC-type enterochelin transport system periplasmic component
OO774_RS16500	COG4774	siderophore transport
OO774_RS16505	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OO774_RS16520	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OO774_RS16540	COG1169	isochorismate synthase
OO774_RS16545	COG1021	2,3-dihydroxybenzoate-AMP ligase
OO774_RS16550	COG3433	isochorismatase activity
OO774_RS16550	COG1535	isochorismatase
OO774_RS16565	COG3706	GGDEF domain
OO774_RS16570	COG0071	Belongs to the small heat shock protein (HSP20) family
OO774_RS16605	COG1448	Aminotransferase
OO774_RS16625	COG3064	Membrane
OO774_RS16625	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
OO774_RS16625	COG1073	alpha beta
OO774_RS16635	COG0741	lytic transglycosylase activity
OO774_RS16670	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OO774_RS16675	COG3437	response regulator, receiver
OO774_RS16695	COG3833	ABC-type maltose transport systems, permease component
OO774_RS16700	COG1175	transmembrane transport
OO774_RS16710	COG3842	ATPase activity
OO774_RS16715	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
OO774_RS16730	COG0489	protein tyrosine kinase activity
OO774_RS16730	COG3206	protein involved in exopolysaccharide biosynthesis
OO774_RS16740	COG0438	transferase activity, transferring glycosyl groups
OO774_RS16770	COG3097	Belongs to the UPF0267 family
OO774_RS16775	COG1309	transcriptional regulator
OO774_RS16780	COG2130	NADP-dependent
OO774_RS16790	COG2084	Dehydrogenase
OO774_RS16795	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OO774_RS16800	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
OO774_RS16810	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OO774_RS16825	COG1012	belongs to the aldehyde dehydrogenase family
OO774_RS16835	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OO774_RS16840	COG0583	DNA-binding transcription factor activity
OO774_RS16845	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
OO774_RS16850	COG2986	histidine ammonia-lyase
OO774_RS16865	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
OO774_RS16870	COG3697	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
OO774_RS16875	COG3051	citrate lyase alpha subunit
OO774_RS16880	COG2301	Belongs to the HpcH HpaI aldolase family
OO774_RS16890	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
OO774_RS16900	COG3630	sodium ion export across plasma membrane
OO774_RS16905	COG0511	ligase activity, forming carbon-carbon bonds
OO774_RS16905	COG5016	pyruvate
OO774_RS16910	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
OO774_RS16920	COG4565	transcriptional regulatory protein
OO774_RS16930	COG1846	Transcriptional regulator
OO774_RS16940	COG1309	transcriptional regulator
OO774_RS16965	COG2351	hydroxyisourate hydrolase activity
OO774_RS16975	COG2233	PERMEase
OO774_RS16980	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OO774_RS17020	COG4566	intracellular signal transduction
OO774_RS17025	COG4191	Histidine kinase
OO774_RS17030	COG0318	PFAM AMP-dependent synthetase and ligase
OO774_RS17035	COG0659	secondary active sulfate transmembrane transporter activity
OO774_RS17040	COG0583	DNA-binding transcription factor activity
OO774_RS17045	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
OO774_RS17050	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
OO774_RS17055	COG0574	Belongs to the PEP-utilizing enzyme family
OO774_RS17055	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
OO774_RS17070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
OO774_RS17085	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OO774_RS17115	COG3842	ATPase activity
OO774_RS17130	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OO774_RS17140	COG4628	conserved protein (DUF2132)
OO774_RS17145	COG1686	Belongs to the peptidase S11 family
OO774_RS17155	COG1054	Belongs to the UPF0176 family
OO774_RS17160	COG4667	esterase of the alpha-beta hydrolase superfamily
OO774_RS17165	COG2095	MarC family integral membrane protein
OO774_RS17180	COG1301	dicarboxylic acid transport
OO774_RS17185	COG3339	Conserved Protein
OO774_RS17190	COG0366	Alpha amylase catalytic
OO774_RS17195	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OO774_RS17200	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
OO774_RS17205	COG1640	4-alpha-glucanotransferase
OO774_RS17210	COG0058	SHG alpha-glucan phosphorylase activity
OO774_RS17215	COG2909	trisaccharide binding
OO774_RS17230	COG1999	signal sequence binding
OO774_RS17235	COG1263	PTS System
OO774_RS17235	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OO774_RS17240	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
OO774_RS17245	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
OO774_RS17260	COG0366	Alpha amylase catalytic
OO774_RS17285	COG1609	Transcriptional regulator
OO774_RS17290	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OO774_RS17290	COG1263	PTS System
OO774_RS17300	COG2814	Major facilitator Superfamily
OO774_RS17310	COG4607	ABC-type enterochelin transport system periplasmic component
OO774_RS17315	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OO774_RS17320	COG4605	iron ion homeostasis
OO774_RS17325	COG4604	ABC transporter, ATP-binding protein
OO774_RS17370	COG4943	cyclic-guanylate-specific phosphodiesterase activity
OO774_RS17405	COG0612	Peptidase, M16
OO774_RS17410	COG5492	domain, Protein
OO774_RS17415	COG5426	von Willebrand factor, type A
OO774_RS17425	COG1085	galactose-1-phosphate uridylyltransferase
OO774_RS17430	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
OO774_RS17435	COG0659	secondary active sulfate transmembrane transporter activity
OO774_RS17445	COG1940	carbohydrate kinase activity
OO774_RS17460	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OO774_RS17470	COG0747	negative chemotaxis
OO774_RS17480	COG0641	radical SAM
OO774_RS17485	COG3119	arylsulfatase activity
OO774_RS17490	COG3119	arylsulfatase activity
OO774_RS17495	COG1653	transport
OO774_RS17500	COG0642	Histidine kinase
OO774_RS17515	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
OO774_RS17520	COG4772	TonB-dependent receptor
OO774_RS17525	COG1172	Belongs to the binding-protein-dependent transport system permease family
OO774_RS17530	COG1172	Belongs to the binding-protein-dependent transport system permease family
OO774_RS17535	COG1129	ABC transporter
OO774_RS17540	COG1879	ABC-type sugar transport system periplasmic component
OO774_RS17560	COG2223	nitrite transmembrane transporter activity
OO774_RS17570	COG1609	Transcriptional regulator
OO774_RS17615	COG1172	Belongs to the binding-protein-dependent transport system permease family
OO774_RS17620	COG1129	ABC transporter
OO774_RS17625	COG1879	ABC-type sugar transport system periplasmic component
OO774_RS17630	COG1069	ribulokinase activity
OO774_RS17640	COG2160	L-arabinose isomerase activity
OO774_RS17650	COG2017	converts alpha-aldose to the beta-anomer
OO774_RS17655	COG3940	Belongs to the glycosyl hydrolase 43 family
OO774_RS17660	COG2211	Major facilitator Superfamily
OO774_RS17670	COG1136	(ABC) transporter
OO774_RS17675	COG0577	efflux transmembrane transporter activity
OO774_RS17700	COG3634	alkyl hydroperoxide reductase activity
OO774_RS17710	COG3119	arylsulfatase activity
OO774_RS17735	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OO774_RS17760	COG0259	pyridoxamine-phosphate oxidase activity
OO774_RS17815	COG1444	tRNA N-acetyltransferase activity
OO774_RS17840	COG4608	Belongs to the ABC transporter superfamily
OO774_RS17845	COG0444	Belongs to the ABC transporter superfamily
OO774_RS17860	COG0217	transcriptional regulatory protein
OO774_RS17870	COG1136	(ABC) transporter
OO774_RS17875	COG4591	ABC-type transport system involved in lipoprotein release permease component
OO774_RS17890	COG3275	phosphorelay sensor kinase activity
OO774_RS17895	COG3279	Response regulator of the LytR AlgR family
OO774_RS17900	COG0786	glutamate:sodium symporter activity
OO774_RS17910	COG1131	(ABC) transporter
OO774_RS17920	COG0363	glucosamine-6-phosphate deaminase activity
OO774_RS17940	COG2259	Doxx family
OO774_RS17955	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OO774_RS17960	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OO774_RS17985	COG0596	Alpha beta hydrolase
OO774_RS17990	COG3123	guanosine phosphorylase activity
OO774_RS17995	COG5001	Diguanylate cyclase
OO774_RS18000	COG0534	Mate efflux family protein
OO774_RS18005	COG0564	pseudouridine synthase activity
OO774_RS18010	COG0561	phosphatase activity
OO774_RS18015	COG2199	diguanylate cyclase activity
OO774_RS18030	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
OO774_RS18045	COG0583	DNA-binding transcription factor activity
OO774_RS18050	COG1414	Transcriptional regulator
OO774_RS18055	COG1028	Short-chain dehydrogenase reductase Sdr
OO774_RS18070	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OO774_RS18075	COG0800	Aldolase
OO774_RS18080	COG2375	cellular response to nickel ion
OO774_RS18100	COG3047	cAMP biosynthetic process
OO774_RS18155	COG3005	denitrification pathway
OO774_RS18160	COG0243	molybdopterin cofactor binding
OO774_RS18175	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
OO774_RS18180	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OO774_RS18185	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OO774_RS18190	COG1116	anion transmembrane transporter activity
OO774_RS18195	COG0351	phosphomethylpyrimidine kinase
OO774_RS18200	COG0312	modulator of DNA gyrase
OO774_RS18205	COG0312	modulator of DNA gyrase
OO774_RS18210	COG1901	pseudouridine methyltransferase
OO774_RS18275	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OO774_RS18285	COG0584	glycerophosphoryl diester phosphodiesterase
OO774_RS18290	COG0039	L-malate dehydrogenase activity
OO774_RS18295	COG0745	RESPONSE REGULATOR receiver
OO774_RS18300	COG2205	protein histidine kinase activity
OO774_RS18315	COG0811	peptide transport
OO774_RS18320	COG0811	peptide transport
OO774_RS18325	COG0848	biopolymer transport protein
OO774_RS18345	COG1770	oligopeptidase
OO774_RS18350	COG2814	Major facilitator Superfamily
OO774_RS18355	COG0010	Belongs to the arginase family
OO774_RS18360	COG1166	arginine decarboxylase activity
OO774_RS18370	COG4067	protein conserved in archaea
OO774_RS18370	COG0189	ligase activity
OO774_RS18375	COG0189	ligase activity
OO774_RS18395	COG3706	GGDEF domain
OO774_RS18400	COG1114	Component of the transport system for branched-chain amino acids
OO774_RS18405	COG0579	oxidoreductase
OO774_RS18420	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
OO774_RS18450	COG3706	GGDEF domain
OO774_RS18455	COG3046	protein related to deoxyribodipyrimidine photolyase
OO774_RS18470	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OO774_RS18470	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OO774_RS18475	COG1765	OsmC-like protein
OO774_RS18485	COG3152	Membrane
OO774_RS18495	COG1011	Hydrolase
OO774_RS18515	COG0577	efflux transmembrane transporter activity
OO774_RS18515	COG1136	(ABC) transporter
OO774_RS18520	COG1538	Outer membrane efflux protein
OO774_RS18525	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OO774_RS18530	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
OO774_RS18540	COG1840	ABC-type Fe3 transport system, periplasmic component
OO774_RS18545	COG3842	ATPase activity
OO774_RS18565	COG2866	Carboxypeptidase
OO774_RS18570	COG1760	l-serine dehydratase
OO774_RS18590	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
OO774_RS18605	COG1304	FMN binding
OO774_RS18615	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OO774_RS18620	COG1280	lysine exporter protein (LysE YggA)
OO774_RS18640	COG4303	Ethanolamine ammonia lyase large subunit
OO774_RS18645	COG4302	ethanolamine ammonia-lyase activity
OO774_RS18650	COG0531	amino acid
OO774_RS18655	COG3385	transposase activity
OO774_RS18670	COG1335	isochorismatase
OO774_RS18680	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
OO774_RS18700	COG0583	DNA-binding transcription factor activity
OO774_RS18705	COG3015	lipoprotein NlpE involved in copper resistance
OO774_RS18710	COG1342	Belongs to the UPF0251 family
OO774_RS18760	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OO774_RS18775	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
OO774_RS18780	COG0628	permease
OO774_RS18790	COG1566	PFAM secretion protein HlyD family protein
OO774_RS18840	COG0346	lactoylglutathione lyase activity
OO774_RS18860	COG3300	MHYT domain
OO774_RS18860	COG5001	Diguanylate cyclase
OO774_RS18865	COG0156	8-amino-7-oxononanoate synthase activity
OO774_RS18870	COG1063	alcohol dehydrogenase
OO774_RS18890	COG1918	ferrous iron import across plasma membrane
OO774_RS18890	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
OO774_RS18895	COG1278	Cold shock
OO774_RS18905	COG0668	transmembrane transport
OO774_RS18915	COG1304	FMN binding
OO774_RS18920	COG1620	l-lactate permease
OO774_RS18925	COG0583	DNA-binding transcription factor activity
OO774_RS18930	COG1505	serine-type exopeptidase activity
OO774_RS18940	COG1067	ATP-dependent peptidase activity
OO774_RS18960	COG0437	4 iron, 4 sulfur cluster binding
OO774_RS18965	COG0348	domain, Protein
OO774_RS18975	COG4720	Psort location CytoplasmicMembrane, score
OO774_RS18980	COG1566	PFAM secretion protein HlyD family protein
OO774_RS18990	COG3706	GGDEF domain
OO774_RS19005	COG0813	purine-nucleoside phosphorylase activity
OO774_RS19010	COG3272	Protein of unknown function (DUF1722)
OO774_RS19015	COG0789	Transcriptional regulator
OO774_RS19020	COG0415	Belongs to the DNA photolyase family
OO774_RS19025	COG1376	ErfK ybiS ycfS ynhG family protein
OO774_RS19025	COG1388	LysM domain
OO774_RS19135	COG4695	Portal protein
OO774_RS19185	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
OO774_RS19275	COG0513	Belongs to the DEAD box helicase family
OO774_RS19290	COG0573	inorganic phosphate transmembrane transporter activity
OO774_RS19295	COG0581	inorganic phosphate transmembrane transporter activity
OO774_RS19300	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
OO774_RS19310	COG2304	oxidoreductase activity
OO774_RS19330	COG0714	Associated with various cellular activities
OO774_RS19345	COG2197	response regulator
OO774_RS19360	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OO774_RS19375	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
OO774_RS19380	COG1120	ATPase activity
OO774_RS19385	COG4774	siderophore transport
OO774_RS19390	COG1132	(ABC) transporter
OO774_RS19395	COG3122	Protein conserved in bacteria
OO774_RS19400	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
OO774_RS19405	COG1012	belongs to the aldehyde dehydrogenase family
OO774_RS19410	COG1522	sequence-specific DNA binding
OO774_RS19415	COG3608	succinylglutamate desuccinylase aspartoacylase
OO774_RS19420	COG0006	proline dipeptidase activity
OO774_RS19425	COG1609	Transcriptional regulator
OO774_RS19430	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OO774_RS19435	COG2723	6-phospho-beta-galactosidase activity
OO774_RS19440	COG2190	(PTS) system
OO774_RS19440	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OO774_RS19440	COG1263	PTS System
OO774_RS19445	COG2723	6-phospho-beta-galactosidase activity
OO774_RS19455	COG1028	Short-chain dehydrogenase reductase Sdr
OO774_RS19470	COG0513	Belongs to the DEAD box helicase family
OO774_RS19495	COG1028	Short-chain dehydrogenase reductase Sdr
OO774_RS19500	COG0625	glutathione transferase activity
OO774_RS19505	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
OO774_RS19505	COG0678	peroxiredoxin activity
OO774_RS19510	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
OO774_RS19525	COG1278	Cold shock
OO774_RS19530	COG1741	Belongs to the pirin family
OO774_RS19535	COG3304	Inner membrane component domain
OO774_RS19540	COG0673	inositol 2-dehydrogenase activity
OO774_RS19545	COG2194	sulfuric ester hydrolase activity
OO774_RS19550	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
OO774_RS19565	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
OO774_RS19575	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
OO774_RS19585	COG1418	mRNA catabolic process
OO774_RS19590	COG2239	Acts as a magnesium transporter
OO774_RS19595	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
OO774_RS19600	COG0531	amino acid
OO774_RS19605	COG1522	sequence-specific DNA binding
OO774_RS19610	COG0583	DNA-binding transcription factor activity
OO774_RS19630	COG0673	inositol 2-dehydrogenase activity
OO774_RS19640	COG2926	Belongs to the UPF0265 family
OO774_RS19650	COG3132	Protein of unknown function, DUF480
OO774_RS19655	COG2827	Endonuclease containing a URI domain
OO774_RS19660	COG1879	ABC-type sugar transport system periplasmic component
OO774_RS19665	COG2205	protein histidine kinase activity
OO774_RS19665	COG0784	Response regulator, receiver
OO774_RS19715	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OO774_RS19720	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OO774_RS19725	COG1280	lysine exporter protein (LysE YggA)
OO774_RS19735	COG0183	Belongs to the thiolase family
OO774_RS19765	COG0243	molybdopterin cofactor binding
OO774_RS19775	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
OO774_RS19780	COG3850	Histidine kinase
OO774_RS19785	COG2197	response regulator
OO774_RS19800	COG2195	Cleaves the N-terminal amino acid of tripeptides
OO774_RS19820	COG0840	transmembrane signaling receptor activity
OO774_RS19830	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OO774_RS19840	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
OO774_RS19845	COG0840	transmembrane signaling receptor activity
OO774_RS19850	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
OO774_RS19855	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
OO774_RS19865	COG2358	TRAP transporter, solute receptor (TAXI family
OO774_RS19875	COG2897	thiosulfate sulfurtransferase activity
OO774_RS19885	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
OO774_RS19905	COG0038	chloride channel
OO774_RS19920	COG4989	oxidoreductase activity
OO774_RS19925	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
OO774_RS19925	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
OO774_RS19930	COG0516	GMP reductase activity
OO774_RS19950	COG1609	Transcriptional regulator
OO774_RS19960	COG2182	Extracellular solute-binding protein
OO774_RS19965	COG1175	transmembrane transport
OO774_RS19970	COG3833	ABC-type maltose transport systems, permease component
OO774_RS19980	COG1874	Beta-galactosidase
OO774_RS19985	COG4580	involved in the transport of maltose and maltodextrins
OO774_RS19995	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
OO774_RS20010	COG2017	converts alpha-aldose to the beta-anomer
OO774_RS20020	COG1609	Transcriptional regulator
OO774_RS20025	COG3250	beta-galactosidase activity
OO774_RS20035	COG4580	involved in the transport of maltose and maltodextrins
OO774_RS20045	COG2211	Major facilitator Superfamily
OO774_RS20050	COG0673	inositol 2-dehydrogenase activity
OO774_RS20060	COG1959	2 iron, 2 sulfur cluster binding
OO774_RS20070	COG1294	oxidase, subunit
OO774_RS20075	COG1271	oxidase subunit
OO774_RS20080	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OO774_RS20090	COG1028	Short-chain dehydrogenase reductase Sdr
OO774_RS20090	COG0604	alcohol dehydrogenase
OO774_RS20090	COG3321	synthase
OO774_RS20115	COG0583	DNA-binding transcription factor activity
OO774_RS20120	COG1380	Effector of murein hydrolase LrgA
OO774_RS20125	COG1346	cytolysis
OO774_RS20150	COG1414	Transcriptional regulator
OO774_RS20155	COG0596	Alpha beta hydrolase
OO774_RS20160	COG0183	Belongs to the thiolase family
OO774_RS20165	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
OO774_RS20170	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
OO774_RS20180	COG4948	Mandelate Racemase Muconate Lactonizing
OO774_RS20190	COG3485	protocatechuate 3,4-dioxygenase
OO774_RS20215	COG2814	Major facilitator Superfamily
OO774_RS20225	COG1902	pentaerythritol trinitrate reductase activity
OO774_RS20230	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OO774_RS20240	COG0583	DNA-binding transcription factor activity
OO774_RS20255	COG3385	transposase activity
OO774_RS20270	COG0789	Transcriptional regulator
OO774_RS20275	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OO774_RS20280	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OO774_RS20290	COG2814	Major facilitator Superfamily
OO774_RS20295	COG0656	L-ascorbic acid biosynthetic process
OO774_RS20315	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
OO774_RS20325	COG1120	ATPase activity
OO774_RS20350	COG0579	oxidoreductase
OO774_RS20370	COG0583	DNA-binding transcription factor activity
OO774_RS20380	COG0667	Aldo Keto reductase
OO774_RS20395	COG0583	DNA-binding transcription factor activity
OO774_RS20400	COG2159	amidohydrolase
OO774_RS20405	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
OO774_RS20485	COG1012	belongs to the aldehyde dehydrogenase family
OO774_RS20485	COG2030	dehydratase
OO774_RS20490	COG3396	Phenylacetate-CoA oxygenase
OO774_RS20495	COG3460	Phenylacetate-CoA oxygenase
OO774_RS20500	COG3396	Phenylacetate-CoA oxygenase
OO774_RS20505	COG2151	metal-sulfur cluster biosynthetic enzyme
OO774_RS20510	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OO774_RS20515	COG1024	Enoyl-CoA hydratase
OO774_RS20520	COG1024	Enoyl-CoA hydratase
OO774_RS20525	COG1250	3-hydroxyacyl-CoA dehydrogenase
OO774_RS20530	COG2050	protein possibly involved in aromatic compounds catabolism
OO774_RS20535	COG0183	Belongs to the thiolase family
OO774_RS20540	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
OO774_RS20545	COG3327	negative regulation of DNA-templated transcription, initiation
OO774_RS20595	COG0402	S-adenosylhomocysteine deaminase activity
OO774_RS20600	COG0656	L-ascorbic acid biosynthetic process
OO774_RS20605	COG1349	DNA-binding transcription factor activity
OO774_RS20610	COG2084	Dehydrogenase
OO774_RS20615	COG3395	kinase activity
OO774_RS20620	COG0235	Class ii aldolase
OO774_RS20625	COG3622	Belongs to the hyi family
OO774_RS20630	COG2610	gluconate transmembrane transporter activity
OO774_RS20635	COG1929	Belongs to the glycerate kinase type-1 family
OO774_RS20640	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
OO774_RS20640	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OO774_RS20665	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
OO774_RS20675	COG1355	regulation of microtubule-based process
OO774_RS20695	COG2814	Major facilitator Superfamily
OO774_RS20700	COG0697	spore germination
OO774_RS20705	COG0840	transmembrane signaling receptor activity
OO774_RS20795	COG3474	cytochrome
OO774_RS20810	COG0583	DNA-binding transcription factor activity
OO774_RS20835	COG4948	Mandelate Racemase Muconate Lactonizing
OO774_RS20845	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
OO774_RS20870	COG4770	biotin carboxylase activity
OO774_RS20880	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
OO774_RS20885	COG1960	acyl-CoA dehydrogenase activity
OO774_RS20895	COG0183	Belongs to the thiolase family
OO774_RS20905	COG1960	acyl-CoA dehydrogenase activity
OO774_RS20910	COG1024	Enoyl-CoA hydratase
OO774_RS20925	COG1028	Short-chain dehydrogenase reductase Sdr
OO774_RS20930	COG1309	transcriptional regulator
OO774_RS20935	COG1012	belongs to the aldehyde dehydrogenase family
OO774_RS20950	COG4176	ABC-type proline glycine betaine transport system permease component
OO774_RS20955	COG0517	IMP dehydrogenase activity
OO774_RS20955	COG4175	Glycine betaine
OO774_RS20960	COG0330	HflC and HflK could
OO774_RS20970	COG5001	Diguanylate cyclase
OO774_RS20970	COG3300	MHYT domain
OO774_RS20995	COG2197	response regulator
OO774_RS21000	COG0515	serine threonine protein kinase
OO774_RS21000	COG2815	serine threonine protein kinase
OO774_RS21005	COG2223	nitrite transmembrane transporter activity
OO774_RS21015	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OO774_RS21020	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
OO774_RS21020	COG1648	precorrin-2 dehydrogenase activity
OO774_RS21025	COG0243	molybdopterin cofactor binding
OO774_RS21120	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
OO774_RS21145	COG3265	gluconokinase activity
OO774_RS21160	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
OO774_RS21165	COG1280	lysine exporter protein (LysE YggA)
OO774_RS21170	COG4628	conserved protein (DUF2132)
OO774_RS21175	COG1278	Cold shock
OO774_RS21195	COG4191	Histidine kinase
OO774_RS21195	COG0784	Response regulator, receiver
OO774_RS21200	COG4657	Part of a membrane complex involved in electron transport
OO774_RS21205	COG2878	Part of a membrane complex involved in electron transport
OO774_RS21210	COG4656	Part of a membrane complex involved in electron transport
OO774_RS21215	COG4658	electron transport chain
OO774_RS21265	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OO774_RS21270	COG3962	Belongs to the TPP enzyme family
OO774_RS21275	COG1012	belongs to the aldehyde dehydrogenase family
OO774_RS21275	COG1454	alcohol dehydrogenase
OO774_RS21285	COG1082	Xylose isomerase domain protein TIM barrel
OO774_RS21295	COG1082	Xylose isomerase domain protein TIM barrel
OO774_RS21300	COG0477	Major facilitator Superfamily
OO774_RS21300	COG2814	Major facilitator Superfamily
OO774_RS21305	COG0673	inositol 2-dehydrogenase activity
OO774_RS21310	COG3718	enzyme involved in inositol metabolism
OO774_RS21320	COG2610	gluconate transmembrane transporter activity
OO774_RS21325	COG1454	alcohol dehydrogenase
OO774_RS21375	COG5001	Diguanylate cyclase
OO774_RS21380	COG1869	D-ribose catabolic process
OO774_RS21385	COG1129	ABC transporter
OO774_RS21390	COG1172	Belongs to the binding-protein-dependent transport system permease family
OO774_RS21395	COG1879	ABC-type sugar transport system periplasmic component
OO774_RS21400	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OO774_RS21405	COG1609	Transcriptional regulator
OO774_RS21415	COG0789	Transcriptional regulator
OO774_RS21420	COG2207	Transcriptional regulator
OO774_RS21425	COG1629	transport
OO774_RS21425	COG4771	TonB-dependent receptor
OO774_RS21440	COG1289	transmembrane transporter activity
OO774_RS21445	COG0210	DNA helicase
OO774_RS21450	COG1803	Methylglyoxal synthase
OO774_RS21455	COG1879	ABC-type sugar transport system periplasmic component
OO774_RS21460	COG0784	Response regulator, receiver
OO774_RS21460	COG2198	Histidine kinase
OO774_RS21460	COG2205	protein histidine kinase activity
OO774_RS21480	COG3119	arylsulfatase activity
OO774_RS21485	COG0641	radical SAM
OO774_RS21490	COG0714	Associated with various cellular activities
OO774_RS21540	COG3069	C4-dicarboxylate transmembrane transporter activity
OO774_RS21550	COG1214	PFAM Peptidase M22, glycoprotease
OO774_RS21550	COG0456	acetyltransferase
OO774_RS21560	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
OO774_RS21570	COG3300	MHYT domain
OO774_RS21570	COG5001	Diguanylate cyclase
OO774_RS21580	COG3706	GGDEF domain
OO774_RS21590	COG2197	response regulator
OO774_RS21625	COG0471	metal ion transport
OO774_RS21630	COG3290	protein histidine kinase activity
OO774_RS21645	COG0069	glutamate synthase activity
OO774_RS21650	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
OO774_RS21685	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
OO774_RS21705	COG4670	ketone body catabolic process
OO774_RS21710	COG1028	Short-chain dehydrogenase reductase Sdr
OO774_RS21715	COG1737	Transcriptional regulator
OO774_RS21725	COG0765	amino acid transport
OO774_RS21730	COG0765	amino acid transport
OO774_RS21745	COG0601	transmembrane transport
OO774_RS21750	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OO774_RS21755	COG4172	Belongs to the ABC transporter superfamily
OO774_RS21790	COG2205	protein histidine kinase activity
OO774_RS21795	COG0745	RESPONSE REGULATOR receiver
OO774_RS21805	COG1846	Transcriptional regulator
OO774_RS21810	COG2130	NADP-dependent
OO774_RS21815	COG0420	3'-5' exonuclease activity
OO774_RS21820	COG0419	ATPase involved in DNA repair
OO774_RS21830	COG3040	lipid binding
OO774_RS21840	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
OO774_RS21845	COG0494	nUDIX hydrolase
OO774_RS21855	COG2425	protein containing a von Willebrand factor type A (vWA) domain
OO774_RS21865	COG0583	DNA-binding transcription factor activity
OO774_RS21870	COG0277	FAD linked oxidase domain protein
OO774_RS21900	COG3746	phosphate-selective porin O and P
OO774_RS21945	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
OO774_RS21950	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OO774_RS21960	COG2116	formate transmembrane transporter activity
OO774_RS21980	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
OO774_RS22005	COG3118	belongs to the thioredoxin family
OO774_RS22010	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OO774_RS22030	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
OO774_RS22035	COG0583	DNA-binding transcription factor activity
OO774_RS22075	COG0583	DNA-binding transcription factor activity
OO774_RS22085	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OO774_RS22090	COG0583	DNA-binding transcription factor activity
OO774_RS22095	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
OO774_RS22125	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OO774_RS22140	COG1328	CTP reductase activity
OO774_RS22145	COG0602	queuosine metabolic process
OO774_RS22150	COG2207	Transcriptional regulator
OO774_RS22160	COG4067	protein conserved in archaea
OO774_RS22160	COG0189	ligase activity
OO774_RS22170	COG1492	cobalamin metabolic process
OO774_RS22175	COG0725	ABC transporter, periplasmic molybdate-binding protein
OO774_RS22180	COG4149	molybdate abc transporter
OO774_RS22185	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
OO774_RS22195	COG4269	membrane
OO774_RS22205	COG5001	Diguanylate cyclase
OO774_RS22205	COG2203	Gaf domain
OO774_RS22205	COG4251	negative regulation of phosphorylation
OO774_RS22205	COG3706	GGDEF domain
OO774_RS22210	COG2199	diguanylate cyclase activity
OO774_RS22220	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
OO774_RS22225	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
OO774_RS22235	COG0745	RESPONSE REGULATOR receiver
OO774_RS22250	COG3140	Belongs to the UPF0181 family
OO774_RS22270	COG0789	Transcriptional regulator
OO774_RS22290	COG3609	addiction module antidote protein, CC2985 family
OO774_RS22310	COG2801	Transposase and inactivated derivatives
OO774_RS22345	COG0023	Translation Initiation Factor
OO774_RS22355	COG1181	Belongs to the D-alanine--D-alanine ligase family
OO774_RS22365	COG1042	CoA-binding domain protein
OO774_RS22365	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OO774_RS22365	COG0045	succinate-CoA ligase (ADP-forming) activity
OO774_RS22370	COG0583	DNA-binding transcription factor activity
OO774_RS22375	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
OO774_RS22380	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
OO774_RS22385	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
OO774_RS22390	COG1984	allophanate hydrolase subunit 2
OO774_RS22400	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
OO774_RS22405	COG4181	ATPase activity
OO774_RS22415	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
OO774_RS22420	COG5001	Diguanylate cyclase
OO774_RS22420	COG3300	MHYT domain
OO774_RS22430	COG0484	heat shock protein binding
OO774_RS22465	COG2050	protein possibly involved in aromatic compounds catabolism
OO774_RS22480	COG2067	long-chain fatty acid transport protein
OO774_RS22485	COG2267	carboxylic ester hydrolase activity
OO774_RS22505	COG0737	Belongs to the 5'-nucleotidase family
OO774_RS22510	COG3593	DNA synthesis involved in DNA repair
OO774_RS22520	COG0583	DNA-binding transcription factor activity
OO774_RS22525	COG2116	formate transmembrane transporter activity
OO774_RS22530	COG2353	YceI-like domain
OO774_RS22535	COG3038	cytochrome b561
OO774_RS22550	COG0513	Belongs to the DEAD box helicase family
OO774_RS22555	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
OO774_RS22560	COG0840	transmembrane signaling receptor activity
OO774_RS22565	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OO774_RS22610	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
OO774_RS22625	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
OO774_RS22635	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OO774_RS22640	COG2759	Belongs to the formate--tetrahydrofolate ligase family
OO774_RS22645	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
OO774_RS22650	COG2207	Transcriptional regulator
OO774_RS22655	COG1979	alcohol dehydrogenase
OO774_RS22665	COG1126	abc transporter atp-binding protein
OO774_RS22670	COG0765	amino acid transport
OO774_RS22675	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OO774_RS22680	COG0765	amino acid transport
OO774_RS22695	COG1609	Transcriptional regulator
OO774_RS22700	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
OO774_RS22700	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
OO774_RS22705	COG1105	Belongs to the carbohydrate kinase PfkB family
OO774_RS22710	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OO774_RS22710	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OO774_RS22710	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
OO774_RS22725	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OO774_RS22735	COG0404	The glycine cleavage system catalyzes the degradation of glycine
OO774_RS22745	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
OO774_RS22750	COG0509	glycine decarboxylation via glycine cleavage system
OO774_RS22810	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OO774_RS22820	COG0814	amino acid
OO774_RS22845	COG0443	Heat shock 70 kDa protein
OO774_RS22885	COG3344	reverse transcriptase
OO774_RS22900	COG1349	DNA-binding transcription factor activity
OO774_RS22910	COG0697	spore germination
OO774_RS22920	COG1882	Formate acetyltransferase
OO774_RS22925	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
OO774_RS22930	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
OO774_RS22935	COG1349	DNA-binding transcription factor activity
OO774_RS22940	COG0673	inositol 2-dehydrogenase activity
OO774_RS22945	COG4702	Belongs to the UPF0303 family
OO774_RS22950	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OO774_RS22955	COG0022	dehydrogenase e1 component
OO774_RS22955	COG0508	dehydrogenase complex catalyzes the overall conversion of
OO774_RS22960	COG0508	dehydrogenase complex catalyzes the overall conversion of
OO774_RS22970	COG0574	Belongs to the PEP-utilizing enzyme family
OO774_RS22970	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
OO774_RS22975	COG0543	2 iron, 2 sulfur cluster binding
OO774_RS22985	COG3383	formate dehydrogenase (NAD+) activity
OO774_RS22990	COG2116	formate transmembrane transporter activity
OO774_RS23010	COG1280	lysine exporter protein (LysE YggA)
OO774_RS23030	COG2015	COG2015, Alkyl sulfatase and related hydrolases
OO774_RS23045	COG1067	ATP-dependent peptidase activity
OO774_RS23070	COG1115	amino acid carrier protein
OO774_RS23075	COG4160	amino acid transport
OO774_RS23080	COG4215	(ABC) transporter
OO774_RS23085	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OO774_RS23090	COG1126	abc transporter atp-binding protein
OO774_RS23105	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
OO774_RS23120	COG2040	homocysteine
OO774_RS23125	COG0531	amino acid
OO774_RS23135	COG1902	pentaerythritol trinitrate reductase activity
OO774_RS23140	COG0109	protoheme IX farnesyltransferase activity
OO774_RS23145	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
OO774_RS23150	COG1845	cytochrome c oxidase, subunit III
OO774_RS23155	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OO774_RS23160	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
OO774_RS23165	COG1028	Short-chain dehydrogenase reductase Sdr
OO774_RS23175	COG1024	Enoyl-CoA hydratase
OO774_RS23180	COG1024	Enoyl-CoA hydratase
OO774_RS23185	COG1960	acyl-CoA dehydrogenase activity
OO774_RS23195	COG0183	Belongs to the thiolase family
OO774_RS23205	COG1960	acyl-CoA dehydrogenase activity
OO774_RS23210	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
OO774_RS23245	COG0573	inorganic phosphate transmembrane transporter activity
OO774_RS23250	COG0581	inorganic phosphate transmembrane transporter activity
OO774_RS23255	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
OO774_RS23265	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
OO774_RS23270	COG0513	Belongs to the DEAD box helicase family
OO774_RS23285	COG1320	monovalent cation:proton antiporter activity
OO774_RS23290	COG2212	antiporter activity
OO774_RS23295	COG1863	multisubunit Na H antiporter MnhE subunit
OO774_RS23300	COG0651	ATP synthesis coupled electron transport
OO774_RS23305	COG1006	Multisubunit Na H antiporter MnhC subunit
OO774_RS23310	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
OO774_RS23310	COG2111	Na H antiporter
OO774_RS23315	COG0589	response to stress
OO774_RS23320	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
OO774_RS23330	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
OO774_RS23350	COG2176	DNA-directed DNA polymerase activity
OO774_RS23360	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OO774_RS23365	COG0673	inositol 2-dehydrogenase activity
OO774_RS23380	COG1917	Cupin 2, conserved barrel domain protein
OO774_RS23380	COG4977	sequence-specific DNA binding
OO774_RS23390	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OO774_RS23400	COG1070	Carbohydrate kinase
OO774_RS23435	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
OO774_RS23450	COG2207	Transcriptional regulator
OO774_RS23455	COG1621	beta-fructofuranosidase activity
OO774_RS23460	COG4172	Belongs to the ABC transporter superfamily
OO774_RS23465	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OO774_RS23470	COG0601	transmembrane transport
OO774_RS23475	COG0747	negative chemotaxis
OO774_RS23485	COG2211	Major facilitator Superfamily
OO774_RS23495	COG2207	Transcriptional regulator
OO774_RS23505	COG1085	galactose-1-phosphate uridylyltransferase
OO774_RS23510	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
OO774_RS23515	COG1979	alcohol dehydrogenase
OO774_RS23520	COG1064	alcohol dehydrogenase
OO774_RS23530	COG1760	l-serine dehydratase
OO774_RS23545	COG0446	pyridine nucleotide-disulphide oxidoreductase
OO774_RS23545	COG0404	The glycine cleavage system catalyzes the degradation of glycine
OO774_RS23560	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
OO774_RS23565	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OO774_RS23575	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
OO774_RS23595	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
OO774_RS23600	COG1012	belongs to the aldehyde dehydrogenase family
OO774_RS23610	COG0656	L-ascorbic acid biosynthetic process
OO774_RS23620	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OO774_RS23630	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
OO774_RS23635	COG2181	nitrate reductase activity
OO774_RS23635	COG0247	lactate metabolic process
OO774_RS23640	COG1902	pentaerythritol trinitrate reductase activity
OO774_RS23640	COG0446	pyridine nucleotide-disulphide oxidoreductase
OO774_RS23665	COG1454	alcohol dehydrogenase
OO774_RS23675	COG2814	Major facilitator Superfamily
OO774_RS23680	COG1028	Short-chain dehydrogenase reductase Sdr
OO774_RS23685	COG1846	Transcriptional regulator
OO774_RS23690	COG0235	Class ii aldolase
OO774_RS23695	COG4806	L-rhamnose isomerase
OO774_RS23700	COG1070	Carbohydrate kinase
OO774_RS23710	COG2169	Transcriptional regulator
OO774_RS23710	COG1917	Cupin 2, conserved barrel domain protein
OO774_RS23715	COG2723	6-phospho-beta-galactosidase activity
OO774_RS23720	COG1447	Phosphotransferase system cellobiose-specific component IIA
OO774_RS23745	COG2207	Transcriptional regulator
OO774_RS23750	COG3250	beta-galactosidase activity
OO774_RS23755	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
OO774_RS23765	COG1609	Transcriptional regulator
OO774_RS23770	COG0673	inositol 2-dehydrogenase activity
OO774_RS23775	COG2211	Major facilitator Superfamily
OO774_RS23800	COG1609	Transcriptional regulator
OO774_RS23815	COG1263	PTS System
OO774_RS23815	COG2190	(PTS) system
OO774_RS23815	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OO774_RS23820	COG0583	DNA-binding transcription factor activity
OO774_RS23840	COG1119	ATPase activity
OO774_RS23855	COG0513	Belongs to the DEAD box helicase family
OO774_RS23860	COG0523	cobalamin synthesis protein
OO774_RS23870	COG0133	tryptophan synthase activity
OO774_RS23875	COG1840	ABC-type Fe3 transport system, periplasmic component
OO774_RS23880	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
OO774_RS23885	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
OO774_RS23890	COG3454	Phosphonate metabolism
OO774_RS23895	COG4778	phosphonate C-P lyase system protein PhnL
OO774_RS23900	COG4107	phosphonate C-P lyase system protein PhnK
OO774_RS23905	COG3627	carbon phosphorus lyase activity
OO774_RS23910	COG3626	phosphonate metabolism
OO774_RS23915	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
OO774_RS23920	COG3624	Phosphonate C-P lyase system protein PhnG
OO774_RS23925	COG0583	DNA-binding transcription factor activity
OO774_RS23945	COG2375	cellular response to nickel ion
OO774_RS23955	COG1120	ATPase activity
OO774_RS23960	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OO774_RS23965	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OO774_RS23970	COG4592	Periplasmic binding protein
OO774_RS23975	COG2382	esterase
OO774_RS23985	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OO774_RS23985	COG2169	Transcriptional regulator
OO774_RS24015	COG0110	maltose O-acetyltransferase activity