locus-tag	class	description
IHV80_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IHV80_RS00010	COG0592	DNA-directed DNA polymerase activity
IHV80_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IHV80_RS00020	COG0187	DNA topoisomerase II activity
IHV80_RS00025	COG4667	esterase of the alpha-beta hydrolase superfamily
IHV80_RS00030	COG0071	Belongs to the small heat shock protein (HSP20) family
IHV80_RS00035	COG3977	Valine--pyruvate aminotransferase
IHV80_RS00055	COG4964	Belongs to the GSP D family
IHV80_RS00120	COG0366	Alpha amylase catalytic
IHV80_RS00125	COG0751	glycine-tRNA ligase activity
IHV80_RS00130	COG0752	glycyl-tRNA synthetase alpha subunit
IHV80_RS00135	COG2119	membrane
IHV80_RS00145	COG0425	Belongs to the sulfur carrier protein TusA family
IHV80_RS00160	COG0604	alcohol dehydrogenase
IHV80_RS00165	COG0183	Belongs to the thiolase family
IHV80_RS00170	COG1024	Enoyl-CoA hydratase
IHV80_RS00170	COG1250	3-hydroxyacyl-CoA dehydrogenase
IHV80_RS00175	COG1739	Uncharacterized protein family UPF0029
IHV80_RS00180	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IHV80_RS00230	COG0583	DNA-binding transcription factor activity
IHV80_RS00235	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IHV80_RS00240	COG2960	long-chain fatty acid transporting porin activity
IHV80_RS00245	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IHV80_RS00250	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IHV80_RS00255	COG1309	transcriptional regulator
IHV80_RS00305	COG0601	transmembrane transport
IHV80_RS00310	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IHV80_RS00320	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IHV80_RS00325	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
IHV80_RS00330	COG0339	signal peptide processing
IHV80_RS00335	COG1522	sequence-specific DNA binding
IHV80_RS00340	COG5001	Diguanylate cyclase
IHV80_RS00340	COG5002	protein histidine kinase activity
IHV80_RS00345	COG0742	ribosomal rna small subunit methyltransferase
IHV80_RS00360	COG0589	response to stress
IHV80_RS00365	COG1528	Iron-storage protein
IHV80_RS00400	COG2081	HI0933 family
IHV80_RS00465	COG0789	Transcriptional regulator
IHV80_RS00480	COG1322	Protein conserved in bacteria
IHV80_RS00485	COG2226	methyltransferase
IHV80_RS00490	COG3165	ubiquinone biosynthetic process from chorismate
IHV80_RS00495	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
IHV80_RS00500	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IHV80_RS00505	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IHV80_RS00510	COG0805	protein transport
IHV80_RS00515	COG0084	hydrolase, TatD family'
IHV80_RS00530	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IHV80_RS00530	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IHV80_RS00540	COG0218	Necessary for normal cell division and for the maintenance of normal septation
IHV80_RS00555	COG3078	GTPase activator activity
IHV80_RS00565	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IHV80_RS00575	COG2204	response regulator
IHV80_RS00580	COG3852	Histidine kinase
IHV80_RS00590	COG0174	glutamine synthetase
IHV80_RS00595	COG1217	gtp-binding protein TYPA
IHV80_RS00610	COG1295	ribonuclease BN
IHV80_RS00615	COG1490	D-aminoacyl-tRNA deacylase activity
IHV80_RS00620	COG0456	acetyltransferase
IHV80_RS00630	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
IHV80_RS00640	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
IHV80_RS00645	COG3031	protein transport across the cell outer membrane
IHV80_RS00655	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IHV80_RS00660	COG1459	type II secretion system
IHV80_RS00665	COG2165	general secretion pathway protein
IHV80_RS00670	COG2165	general secretion pathway protein
IHV80_RS00675	COG2165	general secretion pathway protein
IHV80_RS00680	COG4795	General secretion pathway protein
IHV80_RS00685	COG3156	type II secretion system protein K
IHV80_RS00690	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
IHV80_RS00695	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
IHV80_RS00705	COG1218	3'(2'),5'-bisphosphate nucleotidase
IHV80_RS00710	COG0494	nUDIX hydrolase
IHV80_RS00715	COG0316	Belongs to the HesB IscA family
IHV80_RS00715	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
IHV80_RS00720	COG1040	competence protein
IHV80_RS00725	COG0596	Alpha beta hydrolase
IHV80_RS00735	COG2183	response to ionizing radiation
IHV80_RS00740	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IHV80_RS00745	COG1278	Cold shock
IHV80_RS00765	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IHV80_RS00770	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IHV80_RS00775	COG1758	RNA polymerase activity
IHV80_RS00780	COG0194	GDP metabolic process
IHV80_RS00785	COG2252	PERMEase
IHV80_RS00800	COG1278	Cold shock
IHV80_RS00815	COG1561	YicC-like family, N-terminal region
IHV80_RS00820	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
IHV80_RS00825	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IHV80_RS00830	COG1560	Kdo2-lipid A biosynthetic process
IHV80_RS00835	COG1309	transcriptional regulator
IHV80_RS00845	COG2003	Belongs to the UPF0758 family
IHV80_RS00850	COG0227	Belongs to the bacterial ribosomal protein bL28 family
IHV80_RS00855	COG0267	Belongs to the bacterial ribosomal protein bL33 family
IHV80_RS00865	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
IHV80_RS00885	COG0859	PFAM glycosyl transferase family 9
IHV80_RS00890	COG3642	lipopolysaccharide core region biosynthetic process
IHV80_RS00900	COG1519	Transferase
IHV80_RS00910	COG0463	Glycosyl transferase, family 2
IHV80_RS00920	COG1086	Polysaccharide biosynthesis protein
IHV80_RS00925	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
IHV80_RS00930	COG1083	cytidylyl-transferase
IHV80_RS00940	COG2089	acid synthase
IHV80_RS00955	COG3307	-O-antigen
IHV80_RS00960	COG1560	Kdo2-lipid A biosynthetic process
IHV80_RS00980	COG4942	peptidase
IHV80_RS00985	COG1045	serine acetyltransferase
IHV80_RS00995	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
IHV80_RS01000	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IHV80_RS01020	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IHV80_RS01045	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
IHV80_RS01050	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
IHV80_RS01105	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IHV80_RS01110	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IHV80_RS01125	COG1063	alcohol dehydrogenase
IHV80_RS01135	COG0438	transferase activity, transferring glycosyl groups
IHV80_RS01150	COG1088	dTDP-glucose 4,6-dehydratase activity
IHV80_RS01155	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IHV80_RS01160	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IHV80_RS01170	COG0534	Mate efflux family protein
IHV80_RS01175	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
IHV80_RS01195	COG2203	Gaf domain
IHV80_RS01195	COG2199	diguanylate cyclase activity
IHV80_RS01200	COG1285	pathogenesis
IHV80_RS01210	COG1509	lysine 2,3-aminomutase activity
IHV80_RS01215	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IHV80_RS01225	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
IHV80_RS01230	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IHV80_RS01235	COG1053	succinate dehydrogenase
IHV80_RS01240	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
IHV80_RS01250	COG0840	transmembrane signaling receptor activity
IHV80_RS01255	COG0471	metal ion transport
IHV80_RS01255	COG0490	domain, Protein
IHV80_RS01265	COG1162	GTPase activity
IHV80_RS01350	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IHV80_RS01355	COG0802	atpase or kinase
IHV80_RS01360	COG0860	N-Acetylmuramoyl-L-alanine amidase
IHV80_RS01365	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IHV80_RS01370	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IHV80_RS01375	COG1923	regulation of RNA biosynthetic process
IHV80_RS01380	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IHV80_RS01385	COG0330	HflC and HflK could
IHV80_RS01390	COG0330	HflC and HflK could
IHV80_RS01395	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
IHV80_RS01400	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IHV80_RS01405	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
IHV80_RS01410	COG0402	S-adenosylhomocysteine deaminase activity
IHV80_RS01415	COG0557	exoribonuclease II activity
IHV80_RS01420	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IHV80_RS01425	COG0360	Binds together with S18 to 16S ribosomal RNA
IHV80_RS01435	COG0359	binds to the 23S rRNA
IHV80_RS01450	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IHV80_RS01460	COG0432	Pfam Uncharacterised protein family UPF0047
IHV80_RS01465	COG0166	Belongs to the GPI family
IHV80_RS01475	COG0735	belongs to the Fur family
IHV80_RS01610	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IHV80_RS01615	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IHV80_RS01620	COG0175	sulfate reduction
IHV80_RS01705	COG0527	aspartate kinase activity
IHV80_RS01710	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
IHV80_RS01720	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
IHV80_RS01730	COG2197	response regulator
IHV80_RS01735	COG0629	single-stranded DNA binding
IHV80_RS01765	COG0544	peptidyl-prolyl cis-trans isomerase activity
IHV80_RS01770	COG2200	EAL domain
IHV80_RS01770	COG2199	diguanylate cyclase activity
IHV80_RS01795	COG3409	Peptidoglycan-binding domain 1 protein
IHV80_RS01795	COG3267	Type II secretory pathway component ExeA
IHV80_RS01805	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IHV80_RS01810	COG1459	type II secretion system
IHV80_RS01820	COG2165	general secretion pathway protein
IHV80_RS01825	COG2165	general secretion pathway protein
IHV80_RS01855	COG1077	Cell shape determining protein MreB Mrl
IHV80_RS01860	COG1792	Involved in formation and maintenance of cell shape
IHV80_RS01865	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
IHV80_RS01870	COG0424	maF-like protein
IHV80_RS01885	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IHV80_RS01890	COG0312	modulator of DNA gyrase
IHV80_RS01895	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
IHV80_RS01900	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
IHV80_RS01910	COG0564	pseudouridine synthase activity
IHV80_RS01915	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IHV80_RS01920	COG0589	response to stress
IHV80_RS01935	COG1438	arginine binding
IHV80_RS01940	COG0039	L-malate dehydrogenase activity
IHV80_RS01950	COG0142	geranyltranstransferase activity
IHV80_RS01955	COG0261	This protein binds to 23S rRNA in the presence of protein L20
IHV80_RS01960	COG0211	Belongs to the bacterial ribosomal protein bL27 family
IHV80_RS01965	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IHV80_RS01970	COG2966	Psort location CytoplasmicMembrane, score
IHV80_RS01975	COG3610	response to peptide
IHV80_RS01990	COG2967	ApaG domain
IHV80_RS01995	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
IHV80_RS02000	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
IHV80_RS02005	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IHV80_RS02010	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
IHV80_RS02015	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
IHV80_RS02030	COG0066	3-isopropylmalate dehydratase activity
IHV80_RS02040	COG0473	3-isopropylmalate dehydrogenase activity
IHV80_RS02045	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IHV80_RS02080	COG1022	Amp-dependent synthetase and ligase
IHV80_RS02085	COG0028	Belongs to the TPP enzyme family
IHV80_RS02095	COG3706	GGDEF domain
IHV80_RS02105	COG0469	pyruvate kinase activity
IHV80_RS02110	COG1349	DNA-binding transcription factor activity
IHV80_RS02115	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IHV80_RS02120	COG2873	o-acetylhomoserine
IHV80_RS02140	COG1610	YqeY-like protein
IHV80_RS02145	COG0828	Belongs to the bacterial ribosomal protein bS21 family
IHV80_RS02150	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IHV80_RS02155	COG0596	Alpha beta hydrolase
IHV80_RS02160	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
IHV80_RS02165	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IHV80_RS02175	COG1968	undecaprenyl-diphosphatase activity
IHV80_RS02185	COG3267	Type II secretory pathway component ExeA
IHV80_RS02185	COG3409	Peptidoglycan-binding domain 1 protein
IHV80_RS02195	COG4991	sh3 domain protein
IHV80_RS02200	COG0306	phosphate transporter
IHV80_RS02205	COG1392	Phosphate transport regulator
IHV80_RS02210	COG3025	triphosphatase activity
IHV80_RS02215	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IHV80_RS02225	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
IHV80_RS02230	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
IHV80_RS02230	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
IHV80_RS02235	COG1538	Outer membrane efflux protein
IHV80_RS02240	COG0494	nUDIX hydrolase
IHV80_RS02245	COG3151	Protein conserved in bacteria
IHV80_RS02255	COG3150	esterase
IHV80_RS02260	COG0187	DNA topoisomerase II activity
IHV80_RS02270	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IHV80_RS02275	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IHV80_RS02280	COG3105	Protein conserved in bacteria
IHV80_RS02285	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
IHV80_RS02290	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IHV80_RS02295	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
IHV80_RS02300	COG0723	plastoquinol--plastocyanin reductase activity
IHV80_RS02305	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
IHV80_RS02310	COG2857	Cytochrome c1
IHV80_RS02315	COG0625	glutathione transferase activity
IHV80_RS02320	COG2969	positive regulation of protein catabolic process
IHV80_RS02330	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
IHV80_RS02345	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IHV80_RS02355	COG0275	rRNA processing
IHV80_RS02360	COG3116	cell division
IHV80_RS02365	COG0768	penicillin binding
IHV80_RS02370	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IHV80_RS02375	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IHV80_RS02380	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IHV80_RS02385	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IHV80_RS02390	COG0772	Belongs to the SEDS family
IHV80_RS02395	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IHV80_RS02400	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IHV80_RS02405	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
IHV80_RS02410	COG0849	cell division
IHV80_RS02415	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IHV80_RS02420	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
IHV80_RS02425	COG0653	protein targeting
IHV80_RS02430	COG0494	nUDIX hydrolase
IHV80_RS02435	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
IHV80_RS02440	COG0505	Belongs to the CarA family
IHV80_RS02445	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
IHV80_RS02450	COG0730	response to heat
IHV80_RS02455	COG0583	DNA-binding transcription factor activity
IHV80_RS02460	COG0655	NAD(P)H dehydrogenase (quinone) activity
IHV80_RS02465	COG2860	membrane
IHV80_RS02470	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IHV80_RS02480	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IHV80_RS02490	COG0493	'glutamate synthase
IHV80_RS02495	COG0070	glutamate synthase
IHV80_RS02495	COG0069	glutamate synthase activity
IHV80_RS02495	COG0067	glutamate synthase
IHV80_RS02505	COG0069	glutamate synthase activity
IHV80_RS02505	COG0070	glutamate synthase
IHV80_RS02505	COG0067	glutamate synthase
IHV80_RS02510	COG1242	4 iron, 4 sulfur cluster binding
IHV80_RS02515	COG2203	Gaf domain
IHV80_RS02515	COG3706	GGDEF domain
IHV80_RS02515	COG4251	negative regulation of phosphorylation
IHV80_RS02515	COG5001	Diguanylate cyclase
IHV80_RS02520	COG0784	Response regulator, receiver
IHV80_RS02520	COG5002	protein histidine kinase activity
IHV80_RS02520	COG2198	Histidine kinase
IHV80_RS02530	COG0745	RESPONSE REGULATOR receiver
IHV80_RS02535	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IHV80_RS02550	COG0083	homoserine kinase activity
IHV80_RS02555	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IHV80_RS02560	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
IHV80_RS02565	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
IHV80_RS02570	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IHV80_RS02585	COG1115	amino acid carrier protein
IHV80_RS02590	COG3022	response to hydroperoxide
IHV80_RS02595	COG0513	Belongs to the DEAD box helicase family
IHV80_RS02600	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
IHV80_RS02610	COG0716	FMN binding
IHV80_RS02615	COG4974	Belongs to the 'phage' integrase family
IHV80_RS02620	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IHV80_RS02625	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
IHV80_RS02640	COG2204	response regulator
IHV80_RS02665	COG0494	nUDIX hydrolase
IHV80_RS02675	COG0730	response to heat
IHV80_RS02680	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IHV80_RS02685	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IHV80_RS02690	COG1283	sodium-dependent phosphate transmembrane transporter activity
IHV80_RS02695	COG0583	DNA-binding transcription factor activity
IHV80_RS02700	COG0640	Transcriptional regulator
IHV80_RS02705	COG0268	Binds directly to 16S ribosomal RNA
IHV80_RS02710	COG0728	peptidoglycan biosynthetic process
IHV80_RS02715	COG0196	riboflavin kinase activity
IHV80_RS02720	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IHV80_RS02730	COG1047	Peptidyl-prolyl cis-trans
IHV80_RS02735	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
IHV80_RS02740	COG3279	Response regulator of the LytR AlgR family
IHV80_RS02745	COG3275	phosphorelay sensor kinase activity
IHV80_RS02750	COG1966	Carbon starvation protein
IHV80_RS02760	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
IHV80_RS02765	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
IHV80_RS02770	COG2971	BadF BadG BcrA BcrD
IHV80_RS02790	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IHV80_RS02795	COG1605	Chorismate mutase
IHV80_RS02795	COG0287	Prephenate dehydrogenase
IHV80_RS02800	COG0739	heme binding
IHV80_RS02810	COG0488	(ABC) transporter
IHV80_RS02820	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
IHV80_RS02825	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
IHV80_RS02830	COG5001	Diguanylate cyclase
IHV80_RS02835	COG0077	Prephenate dehydratase
IHV80_RS02835	COG1605	Chorismate mutase
IHV80_RS02840	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IHV80_RS02845	COG0741	lytic transglycosylase activity
IHV80_RS02850	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IHV80_RS02855	COG0564	pseudouridine synthase activity
IHV80_RS02860	COG1496	oxidoreductase activity
IHV80_RS02900	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
IHV80_RS02910	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IHV80_RS02915	COG0826	peptidase U32
IHV80_RS02920	COG2974	May be involved in recombination
IHV80_RS02925	COG0745	RESPONSE REGULATOR receiver
IHV80_RS02930	COG5002	protein histidine kinase activity
IHV80_RS02940	COG0248	Ppx GppA phosphatase
IHV80_RS02945	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
IHV80_RS02950	COG0573	inorganic phosphate transmembrane transporter activity
IHV80_RS02955	COG0581	inorganic phosphate transmembrane transporter activity
IHV80_RS02960	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IHV80_RS02965	COG0704	Plays a role in the regulation of phosphate uptake
IHV80_RS02990	COG3142	Participates in the control of copper homeostasis
IHV80_RS02995	COG0450	alkyl hydroperoxide reductase
IHV80_RS03000	COG0583	DNA-binding transcription factor activity
IHV80_RS03010	COG0517	IMP dehydrogenase activity
IHV80_RS03015	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
IHV80_RS03020	COG0343	queuine tRNA-ribosyltransferase activity
IHV80_RS03025	COG1862	Preprotein translocase
IHV80_RS03030	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IHV80_RS03035	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IHV80_RS03040	COG0483	inositol monophosphate 1-phosphatase activity
IHV80_RS03045	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
IHV80_RS03050	COG1959	2 iron, 2 sulfur cluster binding
IHV80_RS03055	COG1104	cysteine desulfurase activity
IHV80_RS03060	COG0822	iron-sulfur transferase activity
IHV80_RS03070	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
IHV80_RS03075	COG0443	Heat shock 70 kDa protein
IHV80_RS03085	COG2975	iron-sulfur cluster assembly
IHV80_RS03090	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IHV80_RS03095	COG0105	UTP biosynthetic process
IHV80_RS03100	COG0820	rRNA (adenine-C2-)-methyltransferase activity
IHV80_RS03105	COG1426	Protein conserved in bacteria
IHV80_RS03110	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
IHV80_RS03115	COG0124	histidyl-tRNA synthetase
IHV80_RS03120	COG2976	Protein conserved in bacteria
IHV80_RS03125	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IHV80_RS03130	COG1160	GTP binding
IHV80_RS03140	COG3706	GGDEF domain
IHV80_RS03155	COG2885	chlorophyll binding
IHV80_RS03165	COG1570	exodeoxyribonuclease VII activity
IHV80_RS03170	COG0516	GMP reductase activity
IHV80_RS03170	COG0517	IMP dehydrogenase activity
IHV80_RS03175	COG0519	Catalyzes the synthesis of GMP from XMP
IHV80_RS03175	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IHV80_RS03185	COG1757	Na H antiporter
IHV80_RS03190	COG1584	GPR1 FUN34 yaaH family protein
IHV80_RS03195	COG1115	amino acid carrier protein
IHV80_RS03200	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
IHV80_RS03205	COG0204	Acyl-transferase
IHV80_RS03215	COG2391	methyltransferase activity
IHV80_RS03230	COG0189	ligase activity
IHV80_RS03230	COG4067	protein conserved in archaea
IHV80_RS03300	COG2867	negative regulation of translational initiation
IHV80_RS03305	COG2914	Belongs to the UPF0125 (RnfH) family
IHV80_RS03315	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IHV80_RS03320	COG0497	DNA recombination
IHV80_RS03330	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IHV80_RS03335	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IHV80_RS03345	COG0443	Heat shock 70 kDa protein
IHV80_RS03350	COG0484	heat shock protein binding
IHV80_RS03380	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
IHV80_RS03385	COG1253	flavin adenine dinucleotide binding
IHV80_RS03400	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IHV80_RS03400	COG0047	phosphoribosylformylglycinamidine synthase activity
IHV80_RS03410	COG2171	N-acyltransferase activity
IHV80_RS03420	COG2095	MarC family integral membrane protein
IHV80_RS03435	COG3141	response to X-ray
IHV80_RS03450	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
IHV80_RS03455	COG1074	ATP-dependent DNA helicase activity
IHV80_RS03460	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IHV80_RS03470	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
IHV80_RS03470	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
IHV80_RS03480	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
IHV80_RS03485	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
IHV80_RS03495	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IHV80_RS03500	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IHV80_RS03505	COG3248	Nucleoside-binding outer membrane protein
IHV80_RS03515	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IHV80_RS03525	COG2813	Specifically methylates the guanine in position
IHV80_RS03530	COG0271	Belongs to the BolA IbaG family
IHV80_RS03535	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
IHV80_RS03540	COG1805	sodium ion transport
IHV80_RS03550	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
IHV80_RS03555	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
IHV80_RS03560	COG2871	sodium ion transport
IHV80_RS03565	COG1477	protein flavinylation
IHV80_RS03570	COG2991	Protein conserved in bacteria
IHV80_RS03580	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IHV80_RS03585	COG0840	transmembrane signaling receptor activity
IHV80_RS03590	COG0514	ATP-dependent DNA helicase (RecQ)
IHV80_RS03605	COG0733	neurotransmitter:sodium symporter activity
IHV80_RS03610	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IHV80_RS03615	COG0321	lipoyl(octanoyl) transferase activity
IHV80_RS03625	COG1686	Belongs to the peptidase S11 family
IHV80_RS03630	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
IHV80_RS03635	COG0772	Belongs to the SEDS family
IHV80_RS03640	COG0768	penicillin binding
IHV80_RS03645	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IHV80_RS03650	COG0799	negative regulation of ribosome biogenesis
IHV80_RS03655	COG1466	dna polymerase III delta subunit
IHV80_RS03660	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
IHV80_RS03665	COG0495	leucyl-tRNA aminoacylation
IHV80_RS03670	COG2888	peptidyl-tyrosine sulfation
IHV80_RS03675	COG0815	Transfers the fatty acyl group on membrane lipoproteins
IHV80_RS03680	COG4535	Mg2 and Co2 transporter CorC
IHV80_RS03685	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IHV80_RS03690	COG1702	phosphate starvation-inducible protein PhoH
IHV80_RS03700	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IHV80_RS03705	COG2706	6-phosphogluconolactonase activity
IHV80_RS03810	COG0193	aminoacyl-tRNA hydrolase activity
IHV80_RS03815	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IHV80_RS03820	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
IHV80_RS03825	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
IHV80_RS03830	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
IHV80_RS03835	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IHV80_RS03840	COG2890	protein-(glutamine-N5) methyltransferase activity
IHV80_RS03845	COG3094	Invasion gene expression up-regulator, SirB
IHV80_RS03850	COG2912	Transglutaminase-like superfamily
IHV80_RS03855	COG2877	3-deoxy-8-phosphooctulonate synthase activity
IHV80_RS03865	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IHV80_RS03870	COG1187	pseudouridine synthase activity
IHV80_RS03875	COG2840	Smr protein MutS2
IHV80_RS03915	COG1462	curli production assembly transport component CsgG
IHV80_RS03945	COG2217	Heavy metal translocating P-type atpase
IHV80_RS03945	COG2608	mercury ion transmembrane transporter activity
IHV80_RS03955	COG1802	Transcriptional regulator
IHV80_RS03980	COG2059	Chromate
IHV80_RS03985	COG2059	Chromate
IHV80_RS03995	COG1028	Short-chain dehydrogenase reductase Sdr
IHV80_RS04035	COG1216	Glycosyl transferase, family 2
IHV80_RS04055	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IHV80_RS04060	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IHV80_RS04120	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
IHV80_RS04125	COG0784	Response regulator, receiver
IHV80_RS04125	COG0835	chemotaxis
IHV80_RS04130	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
IHV80_RS04135	COG1815	bacterial-type flagellum-dependent cell motility
IHV80_RS04140	COG1558	bacterial-type flagellum-dependent cell motility
IHV80_RS04150	COG1749	Flagellar hook protein flgE
IHV80_RS04155	COG4787	bacterial-type flagellum-dependent cell motility
IHV80_RS04165	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
IHV80_RS04170	COG1706	bacterial-type flagellum-dependent cell motility
IHV80_RS04175	COG3951	Flagellar rod assembly protein muramidase FlgJ
IHV80_RS04175	COG1705	Flagellar rod assembly protein muramidase FlgJ
IHV80_RS04190	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IHV80_RS04195	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IHV80_RS04200	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IHV80_RS04210	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
IHV80_RS04220	COG1516	flagellar protein fliS
IHV80_RS04240	COG1677	Flagellar hook-basal body complex protein FliE
IHV80_RS04250	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IHV80_RS04300	COG1987	bacterial-type flagellum assembly
IHV80_RS04305	COG1684	flagellar biosynthetic protein fliR
IHV80_RS04340	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
IHV80_RS04345	COG2198	Histidine kinase
IHV80_RS04345	COG0643	Histidine kinase
IHV80_RS04345	COG0784	Response regulator, receiver
IHV80_RS04350	COG2201	protein-glutamate methylesterase activity
IHV80_RS04355	COG1192	Involved in chromosome partitioning
IHV80_RS04370	COG0835	chemotaxis
IHV80_RS04380	COG4133	protoheme IX ABC transporter activity
IHV80_RS04385	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IHV80_RS04390	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IHV80_RS04395	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IHV80_RS04400	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
IHV80_RS04405	COG1138	Cytochrome C-type biogenesis protein
IHV80_RS04410	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IHV80_RS04420	COG3088	subunit of a heme lyase
IHV80_RS04420	COG4235	cytochrome complex assembly
IHV80_RS04425	COG2853	Lipoprotein
IHV80_RS04430	COG2067	long-chain fatty acid transport protein
IHV80_RS04435	COG2067	long-chain fatty acid transport protein
IHV80_RS04450	COG0183	Belongs to the thiolase family
IHV80_RS04455	COG1024	Enoyl-CoA hydratase
IHV80_RS04455	COG1250	3-hydroxyacyl-CoA dehydrogenase
IHV80_RS04465	COG2062	phosphohistidine phosphatase, SixA
IHV80_RS04470	COG2840	Smr protein MutS2
IHV80_RS04475	COG2890	protein-(glutamine-N5) methyltransferase activity
IHV80_RS04480	COG1280	lysine exporter protein (LysE YggA)
IHV80_RS04485	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
IHV80_RS04505	COG1175	transmembrane transport
IHV80_RS04515	COG3842	ATPase activity
IHV80_RS04525	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IHV80_RS04530	COG2070	2-Nitropropane dioxygenase
IHV80_RS04530	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
IHV80_RS04545	COG3321	synthase
IHV80_RS04545	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IHV80_RS04560	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IHV80_RS04565	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
IHV80_RS04570	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
IHV80_RS04575	COG2204	response regulator
IHV80_RS04590	COG0544	peptidyl-prolyl cis-trans isomerase activity
IHV80_RS04595	COG0740	serine-type endopeptidase activity
IHV80_RS04600	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IHV80_RS04605	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
IHV80_RS04610	COG0776	regulation of translation
IHV80_RS04615	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IHV80_RS04620	COG1555	photosystem II stabilization
IHV80_RS04635	COG0232	Belongs to the dGTPase family. Type 2 subfamily
IHV80_RS04640	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
IHV80_RS04645	COG0436	Aminotransferase
IHV80_RS04650	COG1169	isochorismate synthase
IHV80_RS04655	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
IHV80_RS04660	COG2267	carboxylic ester hydrolase activity
IHV80_RS04665	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
IHV80_RS04680	COG2190	(PTS) system
IHV80_RS04680	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IHV80_RS04680	COG1263	PTS System
IHV80_RS04685	COG0583	DNA-binding transcription factor activity
IHV80_RS04695	COG2855	membrane
IHV80_RS04760	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IHV80_RS04775	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IHV80_RS04780	COG1522	sequence-specific DNA binding
IHV80_RS04790	COG1946	Acyl-CoA thioesterase
IHV80_RS04795	COG3126	Type III secretion system lipoprotein chaperone (YscW)
IHV80_RS04815	COG2169	Transcriptional regulator
IHV80_RS04815	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IHV80_RS04825	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IHV80_RS04855	COG0328	RNA-DNA hybrid ribonuclease activity
IHV80_RS04855	COG3341	Caulimovirus viroplasmin
IHV80_RS04860	COG0438	transferase activity, transferring glycosyl groups
IHV80_RS04865	COG0463	Glycosyl transferase, family 2
IHV80_RS04865	COG1216	Glycosyl transferase, family 2
IHV80_RS04910	COG0069	glutamate synthase activity
IHV80_RS04915	COG2162	N-hydroxyarylamine O-acetyltransferase activity
IHV80_RS04930	COG0583	DNA-binding transcription factor activity
IHV80_RS04940	COG3394	polysaccharide catabolic process
IHV80_RS04945	COG1486	melibiose metabolic process
IHV80_RS04950	COG0583	DNA-binding transcription factor activity
IHV80_RS04975	COG3119	arylsulfatase activity
IHV80_RS04980	COG1609	Transcriptional regulator
IHV80_RS05005	COG1522	sequence-specific DNA binding
IHV80_RS05010	COG1280	lysine exporter protein (LysE YggA)
IHV80_RS05030	COG0348	domain, Protein
IHV80_RS05035	COG0583	DNA-binding transcription factor activity
IHV80_RS05040	COG1028	Short-chain dehydrogenase reductase Sdr
IHV80_RS05045	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
IHV80_RS05050	COG1227	inorganic diphosphatase activity
IHV80_RS05055	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IHV80_RS05060	COG0006	proline dipeptidase activity
IHV80_RS05065	COG0667	Aldo Keto reductase
IHV80_RS05070	COG0583	DNA-binding transcription factor activity
IHV80_RS05090	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
IHV80_RS05115	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IHV80_RS05120	COG1120	ATPase activity
IHV80_RS05130	COG1228	amidohydrolase
IHV80_RS05155	COG0583	DNA-binding transcription factor activity
IHV80_RS05170	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IHV80_RS05175	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
IHV80_RS05180	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IHV80_RS05185	COG1845	cytochrome c oxidase, subunit III
IHV80_RS05190	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
IHV80_RS05205	COG2015	COG2015, Alkyl sulfatase and related hydrolases
IHV80_RS05225	COG0583	DNA-binding transcription factor activity
IHV80_RS05230	COG0346	lactoylglutathione lyase activity
IHV80_RS05235	COG1902	pentaerythritol trinitrate reductase activity
IHV80_RS05240	COG0697	spore germination
IHV80_RS05265	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IHV80_RS05270	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IHV80_RS05300	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
IHV80_RS05300	COG0617	tRNA 3'-terminal CCA addition
IHV80_RS05300	COG0517	IMP dehydrogenase activity
IHV80_RS05330	COG0537	adenosine 5'-monophosphoramidase activity
IHV80_RS05355	COG3150	esterase
IHV80_RS05360	COG1252	NADH dehydrogenase
IHV80_RS05375	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IHV80_RS05385	COG4591	ABC-type transport system involved in lipoprotein release permease component
IHV80_RS05390	COG1136	(ABC) transporter
IHV80_RS05395	COG4591	ABC-type transport system involved in lipoprotein release permease component
IHV80_RS05405	COG0658	competence protein
IHV80_RS05405	COG2333	competence protein COMEC
IHV80_RS05410	COG1132	(ABC) transporter
IHV80_RS05415	COG1663	tetraacyldisaccharide 4'-kinase activity
IHV80_RS05420	COG2835	tetraacyldisaccharide 4'-kinase activity
IHV80_RS05425	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
IHV80_RS05430	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
IHV80_RS05435	COG0539	negative regulation of cytoplasmic translation
IHV80_RS05440	COG0776	regulation of translation
IHV80_RS05445	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
IHV80_RS05450	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
IHV80_RS05455	COG0284	orotidine-5'-phosphate decarboxylase activity
IHV80_RS05470	COG0583	DNA-binding transcription factor activity
IHV80_RS05480	COG0686	Belongs to the AlaDH PNT family
IHV80_RS05485	COG1522	sequence-specific DNA binding
IHV80_RS05490	COG1674	ftsk spoiiie
IHV80_RS05500	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
IHV80_RS05505	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IHV80_RS05510	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
IHV80_RS05515	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IHV80_RS05520	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
IHV80_RS05525	COG0156	8-amino-7-oxononanoate synthase activity
IHV80_RS05535	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
IHV80_RS05545	COG0534	Mate efflux family protein
IHV80_RS05550	COG0583	DNA-binding transcription factor activity
IHV80_RS05560	COG0501	Belongs to the peptidase M48B family
IHV80_RS05565	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IHV80_RS05570	COG2915	High frequency lysogenization protein hflD homolog
IHV80_RS05585	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IHV80_RS05590	COG2916	Histone family protein nucleoid-structuring protein H-NS
IHV80_RS05595	COG1757	Na H antiporter
IHV80_RS05610	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IHV80_RS05615	COG0131	Imidazoleglycerol-phosphate dehydratase
IHV80_RS05615	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
IHV80_RS05620	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IHV80_RS05625	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
IHV80_RS05630	COG0107	imidazoleglycerol-phosphate synthase activity
IHV80_RS05635	COG0140	phosphoribosyl-ATP diphosphatase activity
IHV80_RS05635	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IHV80_RS05640	COG3012	SEC-C Motif Domain Protein
IHV80_RS05645	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
IHV80_RS05650	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IHV80_RS05655	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IHV80_RS05660	COG0215	cysteine-tRNA ligase activity
IHV80_RS05690	COG2116	formate transmembrane transporter activity
IHV80_RS05695	COG0390	transport system, permease component
IHV80_RS05700	COG4459	periplasmic nitrate reductase
IHV80_RS05705	COG3005	denitrification pathway
IHV80_RS05710	COG0243	molybdopterin cofactor binding
IHV80_RS05720	COG1227	inorganic diphosphatase activity
IHV80_RS05735	COG4172	Belongs to the ABC transporter superfamily
IHV80_RS05745	COG4171	peptide transport system, permease
IHV80_RS05750	COG4168	peptide transport system, permease
IHV80_RS05755	COG4166	transmembrane transport
IHV80_RS05760	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
IHV80_RS05765	COG1842	Phage shock protein A
IHV80_RS05775	COG1983	PspC domain protein
IHV80_RS05780	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IHV80_RS05795	COG2818	Glycosylase
IHV80_RS05800	COG0626	cystathionine gamma-synthase activity
IHV80_RS05810	COG0733	neurotransmitter:sodium symporter activity
IHV80_RS05820	COG0564	pseudouridine synthase activity
IHV80_RS05825	COG0116	Belongs to the methyltransferase superfamily
IHV80_RS05825	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
IHV80_RS05830	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IHV80_RS05835	COG4136	ATPase activity
IHV80_RS05840	COG4135	transport system, permease component
IHV80_RS05845	COG4134	Bacterial extracellular solute-binding protein
IHV80_RS05855	COG3313	Fe-S protein
IHV80_RS05875	COG0513	Belongs to the DEAD box helicase family
IHV80_RS05880	COG1280	lysine exporter protein (LysE YggA)
IHV80_RS05890	COG2866	Carboxypeptidase
IHV80_RS05915	COG4176	ABC-type proline glycine betaine transport system permease component
IHV80_RS05920	COG2113	Glycine betaine
IHV80_RS05930	COG0583	DNA-binding transcription factor activity
IHV80_RS05935	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
IHV80_RS05990	COG2165	general secretion pathway protein
IHV80_RS06005	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
IHV80_RS06015	COG0586	Pfam SNARE associated Golgi protein
IHV80_RS06025	COG0642	Histidine kinase
IHV80_RS06040	COG1061	Type III restriction enzyme res subunit
IHV80_RS06050	COG2814	Major facilitator Superfamily
IHV80_RS06060	COG0702	epimerase
IHV80_RS06065	COG1858	cytochrome C peroxidase
IHV80_RS06075	COG1136	(ABC) transporter
IHV80_RS06090	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
IHV80_RS06095	COG2885	chlorophyll binding
IHV80_RS06095	COG3047	cAMP biosynthetic process
IHV80_RS06120	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
IHV80_RS06130	COG3273	potassium ion transport
IHV80_RS06130	COG2985	domain, Protein
IHV80_RS06135	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IHV80_RS06145	COG1737	Transcriptional regulator
IHV80_RS06150	COG0076	glutamate decarboxylase activity
IHV80_RS06160	COG2431	L-lysine efflux transmembrane transporter activity
IHV80_RS06170	COG3070	regulator of competence-specific genes
IHV80_RS06185	COG4191	Histidine kinase
IHV80_RS06195	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IHV80_RS06210	COG2258	MOSC domain
IHV80_RS06215	COG2176	DNA-directed DNA polymerase activity
IHV80_RS06230	COG1448	Aminotransferase
IHV80_RS06235	COG3437	response regulator, receiver
IHV80_RS06235	COG2770	Histidine kinase
IHV80_RS06245	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IHV80_RS06255	COG0017	Asparaginyl-tRNA synthetase
IHV80_RS06260	COG0840	transmembrane signaling receptor activity
IHV80_RS06270	COG0814	amino acid
IHV80_RS06275	COG1760	l-serine dehydratase
IHV80_RS06280	COG0814	amino acid
IHV80_RS06285	COG0494	nUDIX hydrolase
IHV80_RS06295	COG2205	protein histidine kinase activity
IHV80_RS06295	COG0784	Response regulator, receiver
IHV80_RS06315	COG3106	COG3106 Predicted ATPase
IHV80_RS06330	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IHV80_RS06345	COG0443	Heat shock 70 kDa protein
IHV80_RS06360	COG3706	GGDEF domain
IHV80_RS06370	COG3038	cytochrome b561
IHV80_RS06385	COG3710	Transcriptional regulator
IHV80_RS06415	COG1643	Atp-dependent helicase
IHV80_RS06470	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IHV80_RS06475	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IHV80_RS06475	COG0072	phenylalanine-tRNA ligase activity
IHV80_RS06490	COG1204	response to ionizing radiation
IHV80_RS06500	COG0596	Alpha beta hydrolase
IHV80_RS06585	COG0583	DNA-binding transcription factor activity
IHV80_RS06590	COG0604	alcohol dehydrogenase
IHV80_RS06595	COG1522	sequence-specific DNA binding
IHV80_RS06600	COG2873	o-acetylhomoserine
IHV80_RS06620	COG1289	transmembrane transporter activity
IHV80_RS06645	COG2205	protein histidine kinase activity
IHV80_RS06650	COG0697	spore germination
IHV80_RS06665	COG1342	Belongs to the UPF0251 family
IHV80_RS06700	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
IHV80_RS06715	COG0800	Aldolase
IHV80_RS06750	COG3033	Beta-eliminating lyase
IHV80_RS06795	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
IHV80_RS06805	COG0471	metal ion transport
IHV80_RS06810	COG4191	Histidine kinase
IHV80_RS06810	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IHV80_RS06875	COG1742	UPF0060 membrane protein
IHV80_RS06890	COG0589	response to stress
IHV80_RS06895	COG0659	secondary active sulfate transmembrane transporter activity
IHV80_RS06900	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
IHV80_RS06905	COG1280	lysine exporter protein (LysE YggA)
IHV80_RS06925	COG1115	amino acid carrier protein
IHV80_RS06945	COG1115	amino acid carrier protein
IHV80_RS06960	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IHV80_RS06975	COG3290	protein histidine kinase activity
IHV80_RS06980	COG4565	transcriptional regulatory protein
IHV80_RS06985	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IHV80_RS06990	COG0363	glucosamine-6-phosphate deaminase activity
IHV80_RS06995	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IHV80_RS07005	COG1566	PFAM secretion protein HlyD family protein
IHV80_RS07010	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IHV80_RS07015	COG4628	conserved protein (DUF2132)
IHV80_RS07050	COG3437	response regulator, receiver
IHV80_RS07165	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
IHV80_RS07175	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
IHV80_RS07180	COG0372	Belongs to the citrate synthase family
IHV80_RS07185	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IHV80_RS07220	COG0561	phosphatase activity
IHV80_RS07230	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
IHV80_RS07235	COG3706	GGDEF domain
IHV80_RS07245	COG2885	chlorophyll binding
IHV80_RS07265	COG0840	transmembrane signaling receptor activity
IHV80_RS07270	COG1254	Belongs to the acylphosphatase family
IHV80_RS07275	COG2920	part of a sulfur-relay system
IHV80_RS07280	COG0670	Belongs to the BI1 family
IHV80_RS07285	COG1126	abc transporter atp-binding protein
IHV80_RS07290	COG0765	amino acid transport
IHV80_RS07295	COG4597	amino acid ABC transporter
IHV80_RS07300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IHV80_RS07310	COG1666	GTP binding
IHV80_RS07315	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IHV80_RS07335	COG2996	Protein conserved in bacteria
IHV80_RS07340	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
IHV80_RS07340	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IHV80_RS07345	COG3008	intermembrane lipid transfer
IHV80_RS07350	COG2995	paraquat-inducible protein a
IHV80_RS07355	COG1132	(ABC) transporter
IHV80_RS07360	COG1956	GAF domain-containing protein
IHV80_RS07365	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
IHV80_RS07380	COG0308	aminopeptidase N
IHV80_RS07390	COG2902	Dehydrogenase
IHV80_RS07395	COG0167	dihydroorotate dehydrogenase activity
IHV80_RS07405	COG0116	Belongs to the methyltransferase superfamily
IHV80_RS07405	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
IHV80_RS07415	COG0488	(ABC) transporter
IHV80_RS07435	COG1067	ATP-dependent peptidase activity
IHV80_RS07440	COG3120	sequence-specific DNA binding
IHV80_RS07515	COG4128	Pfam Zonular occludens toxin
IHV80_RS07695	COG2205	protein histidine kinase activity
IHV80_RS07695	COG0784	Response regulator, receiver
IHV80_RS07710	COG3278	Belongs to the heme-copper respiratory oxidase family
IHV80_RS07725	COG2010	Cytochrome c
IHV80_RS07735	COG2217	Heavy metal translocating P-type atpase
IHV80_RS07750	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IHV80_RS07755	COG0589	response to stress
IHV80_RS07760	COG0037	tRNA processing
IHV80_RS07780	COG3842	ATPase activity
IHV80_RS07790	COG1177	transmembrane transport
IHV80_RS07800	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
IHV80_RS07810	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IHV80_RS07815	COG0004	ammonium transporteR
IHV80_RS07830	COG0437	4 iron, 4 sulfur cluster binding
IHV80_RS07835	COG0243	molybdopterin cofactor binding
IHV80_RS07835	COG3383	formate dehydrogenase (NAD+) activity
IHV80_RS07845	COG3381	protein complex oligomerization
IHV80_RS07865	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
IHV80_RS07880	COG3220	belongs to the UPF0276 family
IHV80_RS07895	COG1271	oxidase subunit
IHV80_RS07900	COG1294	oxidase, subunit
IHV80_RS07915	COG0488	(ABC) transporter
IHV80_RS07930	COG0840	transmembrane signaling receptor activity
IHV80_RS07935	COG4191	Histidine kinase
IHV80_RS07950	COG4662	Binding-protein-dependent transport system inner membrane component
IHV80_RS07955	COG3842	ATPase activity
IHV80_RS07960	COG0746	molybdenum cofactor guanylyltransferase activity
IHV80_RS07965	COG0303	'Molybdopterin
IHV80_RS07975	COG1940	carbohydrate kinase activity
IHV80_RS07980	COG3148	PFAM DTW domain containing protein
IHV80_RS07990	COG0840	transmembrane signaling receptor activity
IHV80_RS07995	COG0791	NLP P60 protein
IHV80_RS08015	COG0307	riboflavin synthase, alpha
IHV80_RS08020	COG0534	Mate efflux family protein
IHV80_RS08035	COG2885	chlorophyll binding
IHV80_RS08055	COG2205	protein histidine kinase activity
IHV80_RS08055	COG3437	response regulator, receiver
IHV80_RS08055	COG3850	Histidine kinase
IHV80_RS08055	COG4999	Histidine kinase
IHV80_RS08065	COG4176	ABC-type proline glycine betaine transport system permease component
IHV80_RS08070	COG4175	Glycine betaine
IHV80_RS08070	COG3448	diguanylate cyclase activity
IHV80_RS08080	COG2204	response regulator
IHV80_RS08085	COG0438	transferase activity, transferring glycosyl groups
IHV80_RS08115	COG1215	transferase activity, transferring glycosyl groups
IHV80_RS08120	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
IHV80_RS08125	COG0583	DNA-binding transcription factor activity
IHV80_RS08215	COG1335	isochorismatase
IHV80_RS08225	COG4160	amino acid transport
IHV80_RS08230	COG4215	(ABC) transporter
IHV80_RS08235	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IHV80_RS08240	COG1126	abc transporter atp-binding protein
IHV80_RS08255	COG0826	peptidase U32
IHV80_RS08295	COG1028	Short-chain dehydrogenase reductase Sdr
IHV80_RS08305	COG0546	phosphoglycolate phosphatase activity
IHV80_RS08310	COG0653	protein targeting
IHV80_RS08320	COG1280	lysine exporter protein (LysE YggA)
IHV80_RS08340	COG0346	lactoylglutathione lyase activity
IHV80_RS08355	COG1619	proteins homologs of microcin C7 resistance protein MccF
IHV80_RS08365	COG0730	response to heat
IHV80_RS08390	COG1714	RDD family
IHV80_RS08400	COG0657	acetylesterase activity
IHV80_RS08425	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IHV80_RS08425	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IHV80_RS08465	COG1403	HNH endonuclease
IHV80_RS08490	COG0110	maltose O-acetyltransferase activity
IHV80_RS08500	COG1187	pseudouridine synthase activity
IHV80_RS08515	COG0494	nUDIX hydrolase
IHV80_RS08535	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IHV80_RS08545	COG0584	glycerophosphoryl diester phosphodiesterase
IHV80_RS08550	COG2271	Major facilitator Superfamily
IHV80_RS08585	COG4774	siderophore transport
IHV80_RS08605	COG4615	Cyclic peptide transporter
IHV80_RS08615	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IHV80_RS08620	COG1120	ATPase activity
IHV80_RS08645	COG0589	response to stress
IHV80_RS08655	COG0419	ATPase involved in DNA repair
IHV80_RS08660	COG0420	3'-5' exonuclease activity
IHV80_RS08665	COG1472	Belongs to the glycosyl hydrolase 3 family
IHV80_RS08685	COG0784	Response regulator, receiver
IHV80_RS08685	COG2205	protein histidine kinase activity
IHV80_RS08690	COG1538	Outer membrane efflux protein
IHV80_RS08700	COG1132	(ABC) transporter
IHV80_RS08710	COG0454	-acetyltransferase
IHV80_RS08715	COG2203	Gaf domain
IHV80_RS08715	COG2199	diguanylate cyclase activity
IHV80_RS08725	COG4771	TonB-dependent receptor
IHV80_RS08735	COG3469	chitinase activity
IHV80_RS08745	COG0840	transmembrane signaling receptor activity
IHV80_RS08770	COG2015	COG2015, Alkyl sulfatase and related hydrolases
IHV80_RS08780	COG0583	DNA-binding transcription factor activity
IHV80_RS08785	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IHV80_RS08835	COG0455	bacterial-type flagellum organization
IHV80_RS08845	COG4964	Belongs to the GSP D family
IHV80_RS08865	COG0583	DNA-binding transcription factor activity
IHV80_RS08870	COG1733	regulation of RNA biosynthetic process
IHV80_RS08900	COG2425	protein containing a von Willebrand factor type A (vWA) domain
IHV80_RS08925	COG1196	nuclear chromosome segregation
IHV80_RS08935	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
IHV80_RS08950	COG0210	DNA helicase
IHV80_RS08985	COG2003	Belongs to the UPF0758 family
IHV80_RS09025	COG0582	viral genome integration into host DNA
IHV80_RS09050	COG2195	Cleaves the N-terminal amino acid of tripeptides
IHV80_RS09080	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
IHV80_RS09085	COG3063	Type IV pilus biogenesis stability protein PilW
IHV80_RS09095	COG1451	nucleotide metabolic process
IHV80_RS09105	COG0583	DNA-binding transcription factor activity
IHV80_RS09110	COG2814	Major facilitator Superfamily
IHV80_RS09135	COG5492	domain, Protein
IHV80_RS09135	COG4932	domain protein
IHV80_RS09175	COG0745	RESPONSE REGULATOR receiver
IHV80_RS09185	COG1247	-acetyltransferase
IHV80_RS09200	COG1294	oxidase, subunit
IHV80_RS09205	COG1271	oxidase subunit
IHV80_RS09210	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IHV80_RS09220	COG3397	chitin binding
IHV80_RS09230	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
IHV80_RS09235	COG4139	cobalamin transport
IHV80_RS09240	COG2988	succinylglutamate desuccinylase activity
IHV80_RS09260	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
IHV80_RS09265	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
IHV80_RS09280	COG1823	symporter activity
IHV80_RS09290	COG4989	oxidoreductase activity
IHV80_RS09315	COG3122	Protein conserved in bacteria
IHV80_RS09320	COG3568	Endonuclease Exonuclease Phosphatase
IHV80_RS09365	COG2925	Exonuclease
IHV80_RS09375	COG1346	cytolysis
IHV80_RS09380	COG0295	cytidine deaminase activity
IHV80_RS09385	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
IHV80_RS09390	COG0500	methyltransferase
IHV80_RS09420	COG0776	regulation of translation
IHV80_RS09425	COG1028	Short-chain dehydrogenase reductase Sdr
IHV80_RS09440	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IHV80_RS09455	COG0488	(ABC) transporter
IHV80_RS09460	COG2175	clavaminate synthase activity
IHV80_RS09475	COG0583	DNA-binding transcription factor activity
IHV80_RS09485	COG0840	transmembrane signaling receptor activity
IHV80_RS09490	COG2378	regulation of single-species biofilm formation
IHV80_RS09520	COG0776	regulation of translation
IHV80_RS09550	COG1166	arginine decarboxylase activity
IHV80_RS09555	COG2226	methyltransferase
IHV80_RS09565	COG1309	transcriptional regulator
IHV80_RS09570	COG0488	(ABC) transporter
IHV80_RS09585	COG3097	Belongs to the UPF0267 family
IHV80_RS09590	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IHV80_RS09595	COG0291	Belongs to the bacterial ribosomal protein bL35 family
IHV80_RS09605	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IHV80_RS09615	COG4326	sporulation control protein
IHV80_RS09625	COG1228	amidohydrolase
IHV80_RS09630	COG0010	Belongs to the arginase family
IHV80_RS09635	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
IHV80_RS09640	COG2986	histidine ammonia-lyase
IHV80_RS09655	COG0247	lactate metabolic process
IHV80_RS09655	COG0277	FAD linked oxidase domain protein
IHV80_RS09690	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
IHV80_RS09700	COG1643	Atp-dependent helicase
IHV80_RS09705	COG0281	malic enzyme
IHV80_RS09710	COG2949	membrane
IHV80_RS09715	COG0471	metal ion transport
IHV80_RS09735	COG2199	diguanylate cyclase activity
IHV80_RS09735	COG2203	Gaf domain
IHV80_RS09750	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IHV80_RS09780	COG1301	dicarboxylic acid transport
IHV80_RS09790	COG0251	oxidation-reduction process
IHV80_RS09795	COG0492	ferredoxin-NADP+ reductase activity
IHV80_RS09800	COG4988	ABC transporter
IHV80_RS09805	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
IHV80_RS09815	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IHV80_RS09820	COG1780	Probably involved in ribonucleotide reductase function
IHV80_RS09830	COG0316	Belongs to the HesB IscA family
IHV80_RS09835	COG0719	Fe-S assembly protein
IHV80_RS09840	COG0396	ATPase activity
IHV80_RS09845	COG0719	Fe-S assembly protein
IHV80_RS09850	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IHV80_RS09855	COG2166	iron-sulfur cluster assembly
IHV80_RS09860	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
IHV80_RS09870	COG0840	transmembrane signaling receptor activity
IHV80_RS09875	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IHV80_RS09880	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IHV80_RS09905	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
IHV80_RS09920	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IHV80_RS09925	COG3108	Peptidase M15
IHV80_RS09930	COG2989	Protein conserved in bacteria
IHV80_RS09955	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IHV80_RS09965	COG3088	subunit of a heme lyase
IHV80_RS09965	COG4235	cytochrome complex assembly
IHV80_RS09975	COG1138	Cytochrome C-type biogenesis protein
IHV80_RS09980	COG3301	Polysulphide reductase, NrfD
IHV80_RS09985	COG0437	4 iron, 4 sulfur cluster binding
IHV80_RS09990	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
IHV80_RS10000	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IHV80_RS10015	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IHV80_RS10020	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IHV80_RS10025	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IHV80_RS10045	COG0243	molybdopterin cofactor binding
IHV80_RS10050	COG0437	4 iron, 4 sulfur cluster binding
IHV80_RS10055	COG3302	dmso reductase anchor subunit
IHV80_RS10060	COG1058	Belongs to the CinA family
IHV80_RS10060	COG1546	Belongs to the CinA family
IHV80_RS10075	COG0019	diaminopimelate decarboxylase activity
IHV80_RS10115	COG0322	excinuclease ABC activity
IHV80_RS10120	COG2197	response regulator
IHV80_RS10125	COG0417	DNA replication proofreading
IHV80_RS10135	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IHV80_RS10150	COG1187	pseudouridine synthase activity
IHV80_RS10155	COG0009	L-threonylcarbamoyladenylate synthase
IHV80_RS10160	COG0613	PHP domain protein
IHV80_RS10170	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IHV80_RS10175	COG0512	Glutamine amidotransferase of anthranilate synthase
IHV80_RS10180	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IHV80_RS10185	COG0135	phosphoribosylanthranilate isomerase activity
IHV80_RS10185	COG0134	indole-3-glycerol-phosphate synthase activity
IHV80_RS10190	COG0133	tryptophan synthase activity
IHV80_RS10195	COG0159	tryptophan synthase activity
IHV80_RS10205	COG0330	HflC and HflK could
IHV80_RS10215	COG1301	dicarboxylic acid transport
IHV80_RS10230	COG0583	DNA-binding transcription factor activity
IHV80_RS10240	COG2917	probably involved in intracellular septation
IHV80_RS10245	COG1607	acyl-coa hydrolase
IHV80_RS10250	COG2350	Protein conserved in bacteria
IHV80_RS10260	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IHV80_RS10265	COG0583	DNA-binding transcription factor activity
IHV80_RS10280	COG1032	radical SAM domain protein
IHV80_RS10285	COG1396	sequence-specific DNA binding
IHV80_RS10290	COG3135	benzoate transporter
IHV80_RS10305	COG0463	Glycosyl transferase, family 2
IHV80_RS10310	COG0745	RESPONSE REGULATOR receiver
IHV80_RS10330	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IHV80_RS10335	COG0583	DNA-binding transcription factor activity
IHV80_RS10365	COG1349	DNA-binding transcription factor activity
IHV80_RS10370	COG3118	belongs to the thioredoxin family
IHV80_RS10370	COG0457	Tetratricopeptide repeat
IHV80_RS10375	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
IHV80_RS10385	COG1215	transferase activity, transferring glycosyl groups
IHV80_RS10410	COG2194	sulfuric ester hydrolase activity
IHV80_RS10415	COG0786	glutamate:sodium symporter activity
IHV80_RS10430	COG5002	protein histidine kinase activity
IHV80_RS10430	COG0784	Response regulator, receiver
IHV80_RS10450	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
IHV80_RS10455	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
IHV80_RS10460	COG2885	chlorophyll binding
IHV80_RS10465	COG0823	Involved in the tonB-independent uptake of proteins
IHV80_RS10480	COG0811	peptide transport
IHV80_RS10485	COG0824	Thioesterase
IHV80_RS10495	COG4890	Cyd operon protein YbgT
IHV80_RS10500	COG1294	oxidase, subunit
IHV80_RS10505	COG1271	oxidase subunit
IHV80_RS10510	COG2255	four-way junction helicase activity
IHV80_RS10515	COG0632	four-way junction helicase activity
IHV80_RS10520	COG0840	transmembrane signaling receptor activity
IHV80_RS10525	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
IHV80_RS10530	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
IHV80_RS10535	COG1801	Protein of unknown function DUF72
IHV80_RS10540	COG4106	trans-aconitate 2-methyltransferase activity
IHV80_RS10545	COG0500	methyltransferase
IHV80_RS10550	COG4067	protein conserved in archaea
IHV80_RS10550	COG0189	ligase activity
IHV80_RS10565	COG3383	formate dehydrogenase (NAD+) activity
IHV80_RS10570	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
IHV80_RS10575	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
IHV80_RS10580	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
IHV80_RS10585	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IHV80_RS10590	COG1434	Gram-negative-bacterium-type cell wall biogenesis
IHV80_RS10595	COG0745	RESPONSE REGULATOR receiver
IHV80_RS10600	COG3381	protein complex oligomerization
IHV80_RS10605	COG1609	Transcriptional regulator
IHV80_RS10610	COG3070	regulator of competence-specific genes
IHV80_RS10630	COG0297	glycogen (starch) synthase activity
IHV80_RS10635	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
IHV80_RS10640	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IHV80_RS10650	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
IHV80_RS10660	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
IHV80_RS10665	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
IHV80_RS10670	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IHV80_RS10675	COG0542	response to heat
IHV80_RS10680	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
IHV80_RS10685	COG1278	Cold shock
IHV80_RS10695	COG1187	pseudouridine synthase activity
IHV80_RS10705	COG1199	ATP-dependent helicase activity
IHV80_RS10725	COG2850	peptidyl-arginine hydroxylation
IHV80_RS10730	COG0840	transmembrane signaling receptor activity
IHV80_RS10735	COG2814	Major facilitator Superfamily
IHV80_RS10740	COG1770	oligopeptidase
IHV80_RS10745	COG0708	Exodeoxyribonuclease III
IHV80_RS10755	COG4160	amino acid transport
IHV80_RS10780	COG1882	Formate acetyltransferase
IHV80_RS10790	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IHV80_RS10795	COG3013	Belongs to the UPF0304 family
IHV80_RS10800	COG3713	MltA-interacting MipA family protein
IHV80_RS10805	COG2766	serine protein kinase
IHV80_RS10810	COG2718	Belongs to the UPF0229 family
IHV80_RS10815	COG2719	SpoVR family
IHV80_RS10820	COG0616	signal peptide processing
IHV80_RS10825	COG1028	Short-chain dehydrogenase reductase Sdr
IHV80_RS10845	COG0784	Response regulator, receiver
IHV80_RS10845	COG0835	chemotaxis
IHV80_RS10850	COG1940	carbohydrate kinase activity
IHV80_RS10855	COG0469	pyruvate kinase activity
IHV80_RS10860	COG4667	esterase of the alpha-beta hydrolase superfamily
IHV80_RS10885	COG0084	hydrolase, TatD family'
IHV80_RS10895	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IHV80_RS10900	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IHV80_RS10905	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IHV80_RS10930	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IHV80_RS10935	COG0416	fatty acid biosynthetic process
IHV80_RS10940	COG0333	Belongs to the bacterial ribosomal protein bL32 family
IHV80_RS10945	COG1399	metal-binding, possibly nucleic acid-binding protein
IHV80_RS10950	COG0424	maF-like protein
IHV80_RS10955	COG0564	pseudouridine synthase activity
IHV80_RS10960	COG1530	ribonuclease E activity
IHV80_RS10965	COG0659	secondary active sulfate transmembrane transporter activity
IHV80_RS10970	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IHV80_RS10975	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
IHV80_RS10980	COG2982	Protein involved in outer membrane biogenesis
IHV80_RS10985	COG0572	uridine kinase
IHV80_RS10990	COG0489	protein tyrosine kinase activity
IHV80_RS10995	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IHV80_RS10995	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IHV80_RS11005	COG2186	Transcriptional regulator
IHV80_RS11010	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
IHV80_RS11020	COG0653	protein targeting
IHV80_RS11025	COG2165	general secretion pathway protein
IHV80_RS11030	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IHV80_RS11035	COG3706	GGDEF domain
IHV80_RS11045	COG3092	negative regulation of chromosome organization
IHV80_RS11050	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IHV80_RS11055	COG0280	phosphate acetyltransferase
IHV80_RS11055	COG0857	belongs to the CobB CobQ family
IHV80_RS11060	COG3706	GGDEF domain
IHV80_RS11065	COG0435	Glutathione S-transferase
IHV80_RS11075	COG0444	Belongs to the ABC transporter superfamily
IHV80_RS11080	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IHV80_RS11085	COG0601	transmembrane transport
IHV80_RS11095	COG0314	molybdopterin synthase activity
IHV80_RS11100	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
IHV80_RS11105	COG0315	cyclic pyranopterin monophosphate synthase activity
IHV80_RS11110	COG0521	Mo-molybdopterin cofactor biosynthetic process
IHV80_RS11115	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IHV80_RS11120	COG0391	Required for morphogenesis under gluconeogenic growth conditions
IHV80_RS11125	COG2198	Histidine kinase
IHV80_RS11130	COG2204	response regulator
IHV80_RS11135	COG0556	nucleotide-excision repair
IHV80_RS11145	COG4657	Part of a membrane complex involved in electron transport
IHV80_RS11150	COG2878	Part of a membrane complex involved in electron transport
IHV80_RS11155	COG4656	Part of a membrane complex involved in electron transport
IHV80_RS11160	COG4658	electron transport chain
IHV80_RS11165	COG4659	FMN binding
IHV80_RS11170	COG4660	Part of a membrane complex involved in electron transport
IHV80_RS11175	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IHV80_RS11180	COG0346	lactoylglutathione lyase activity
IHV80_RS11190	COG2885	chlorophyll binding
IHV80_RS11200	COG2056	Na+-H+ antiporter family
IHV80_RS11220	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
IHV80_RS11240	COG1012	belongs to the aldehyde dehydrogenase family
IHV80_RS11240	COG1454	alcohol dehydrogenase
IHV80_RS11245	COG2095	MarC family integral membrane protein
IHV80_RS11250	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IHV80_RS11255	COG2165	general secretion pathway protein
IHV80_RS11260	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IHV80_RS11265	COG1757	Na H antiporter
IHV80_RS11280	COG3081	Nucleoid-associated protein
IHV80_RS11285	COG3082	Protein of unknown function (DUF1414)
IHV80_RS11310	COG1959	2 iron, 2 sulfur cluster binding
IHV80_RS11320	COG0123	including yeast histone deacetylase and acetoin utilization protein
IHV80_RS11335	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IHV80_RS11340	COG0778	Nitroreductase
IHV80_RS11345	COG0446	pyridine nucleotide-disulphide oxidoreductase
IHV80_RS11345	COG1902	pentaerythritol trinitrate reductase activity
IHV80_RS11350	COG0616	signal peptide processing
IHV80_RS11355	COG0252	asparaginase activity
IHV80_RS11360	COG3139	Protein of unknown function (DUF1315)
IHV80_RS11370	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IHV80_RS11375	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IHV80_RS11390	COG2226	methyltransferase
IHV80_RS11410	COG1785	Belongs to the alkaline phosphatase family
IHV80_RS11430	COG2983	Belongs to the UPF0260 family
IHV80_RS11440	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
IHV80_RS11450	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IHV80_RS11455	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IHV80_RS11460	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IHV80_RS11465	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IHV80_RS11470	COG2832	Protein of unknown function (DUF454)
IHV80_RS11480	COG0745	RESPONSE REGULATOR receiver
IHV80_RS11485	COG0583	DNA-binding transcription factor activity
IHV80_RS11490	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IHV80_RS11495	COG1286	toxin biosynthetic process
IHV80_RS11500	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
IHV80_RS11505	COG0285	dihydrofolate synthase activity
IHV80_RS11510	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IHV80_RS11515	COG0101	tRNA pseudouridine synthase activity
IHV80_RS11525	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IHV80_RS11530	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IHV80_RS11535	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IHV80_RS11545	COG0431	NADPH-dependent FMN reductase
IHV80_RS11555	COG3101	peptidyl-lysine hydroxylation
IHV80_RS11560	COG2860	membrane
IHV80_RS11565	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IHV80_RS11570	COG2153	protein acetylation
IHV80_RS11580	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IHV80_RS11590	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IHV80_RS11595	COG0583	DNA-binding transcription factor activity
IHV80_RS11600	COG2951	lytic endotransglycosylase activity
IHV80_RS11605	COG3100	YcgL domain-containing protein
IHV80_RS11610	COG0850	regulation of cytokinetic process
IHV80_RS11615	COG2894	cell division
IHV80_RS11620	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
IHV80_RS11630	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
IHV80_RS11635	COG0318	PFAM AMP-dependent synthetase and ligase
IHV80_RS11640	COG0596	Alpha beta hydrolase
IHV80_RS11655	COG1214	PFAM Peptidase M22, glycoprotease
IHV80_RS11660	COG1199	ATP-dependent helicase activity
IHV80_RS11670	COG0788	formyltetrahydrofolate deformylase activity
IHV80_RS11675	COG3102	Protein conserved in bacteria
IHV80_RS11680	COG0018	arginyl-trna synthetase
IHV80_RS11705	COG1918	ferrous iron import across plasma membrane
IHV80_RS11720	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
IHV80_RS11725	COG1121	(ABC) transporter
IHV80_RS11730	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IHV80_RS11740	COG0045	succinate-CoA ligase (ADP-forming) activity
IHV80_RS11745	COG0508	dehydrogenase complex catalyzes the overall conversion of
IHV80_RS11750	COG0567	Dehydrogenase, E1 component
IHV80_RS11760	COG1053	succinate dehydrogenase
IHV80_RS11765	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
IHV80_RS11775	COG0372	Belongs to the citrate synthase family
IHV80_RS11780	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IHV80_RS11790	COG0033	Phosphoglucomutase
IHV80_RS11795	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
IHV80_RS11800	COG0596	Alpha beta hydrolase
IHV80_RS11825	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IHV80_RS11830	COG2190	(PTS) system
IHV80_RS11830	COG1263	PTS System
IHV80_RS11830	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IHV80_RS11835	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
IHV80_RS11840	COG1846	Transcriptional regulator
IHV80_RS11840	COG1940	carbohydrate kinase activity
IHV80_RS11845	COG4651	solute:proton antiporter activity
IHV80_RS11845	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IHV80_RS11850	COG0367	asparagine synthase
IHV80_RS11855	COG0250	Participates in transcription elongation, termination and antitermination
IHV80_RS11865	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
IHV80_RS11870	COG0563	adenylate kinase activity
IHV80_RS11875	COG0326	Molecular chaperone. Has ATPase activity
IHV80_RS11880	COG3710	Transcriptional regulator
IHV80_RS11895	COG0622	Phosphoesterase
IHV80_RS11920	COG1090	epimerase
IHV80_RS11925	COG0300	oxidoreductase activity
IHV80_RS11930	COG3118	belongs to the thioredoxin family
IHV80_RS11935	COG0330	HflC and HflK could
IHV80_RS11950	COG0789	Transcriptional regulator
IHV80_RS11965	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IHV80_RS11970	COG3115	cell septum assembly
IHV80_RS11975	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
IHV80_RS11985	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IHV80_RS11995	COG2190	(PTS) system
IHV80_RS12000	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IHV80_RS12005	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IHV80_RS12010	COG2837	iron assimilation
IHV80_RS12035	COG1393	Belongs to the ArsC family
IHV80_RS12040	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IHV80_RS12055	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
IHV80_RS12060	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IHV80_RS12065	COG2716	regulation of RNA biosynthetic process
IHV80_RS12070	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IHV80_RS12085	COG1942	4-Oxalocrotonate Tautomerase
IHV80_RS12110	COG4783	chaperone-mediated protein folding
IHV80_RS12115	COG1393	Belongs to the ArsC family
IHV80_RS12135	COG2233	PERMEase
IHV80_RS12145	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
IHV80_RS12150	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IHV80_RS12155	COG0121	glutamine amidotransferase
IHV80_RS12160	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
IHV80_RS12165	COG1960	acyl-CoA dehydrogenase activity
IHV80_RS12175	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IHV80_RS12180	COG0328	RNA-DNA hybrid ribonuclease activity
IHV80_RS12185	COG2226	methyltransferase
IHV80_RS12190	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IHV80_RS12195	COG1388	LysM domain
IHV80_RS12195	COG0741	lytic transglycosylase activity
IHV80_RS12205	COG3021	interspecies interaction between organisms
IHV80_RS12210	COG0347	Belongs to the P(II) protein family
IHV80_RS12220	COG0037	tRNA processing
IHV80_RS12225	COG0825	malonyl-CoA metabolic process
IHV80_RS12230	COG0587	DNA-directed DNA polymerase activity
IHV80_RS12235	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IHV80_RS12245	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IHV80_RS12250	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
IHV80_RS12255	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IHV80_RS12260	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
IHV80_RS12270	COG0750	zinc metalloprotease
IHV80_RS12280	COG0575	Belongs to the CDS family
IHV80_RS12285	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IHV80_RS12290	COG0233	cytoplasmic translational termination
IHV80_RS12295	COG0528	UMP kinase activity
IHV80_RS12300	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IHV80_RS12305	COG0052	Belongs to the universal ribosomal protein uS2 family
IHV80_RS12310	COG0024	Methionine aminopeptidase
IHV80_RS12315	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
IHV80_RS12325	COG0564	pseudouridine synthase activity
IHV80_RS12330	COG3098	single-species biofilm formation
IHV80_RS12355	COG1671	Belongs to the UPF0178 family
IHV80_RS12365	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
IHV80_RS12375	COG0254	rRNA binding
IHV80_RS12380	COG1720	tRNA m6t6A37 methyltransferase activity
IHV80_RS12385	COG0442	prolyl-tRNA aminoacylation
IHV80_RS12410	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IHV80_RS12415	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IHV80_RS12430	COG0366	Alpha amylase catalytic
IHV80_RS12435	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IHV80_RS12435	COG1263	PTS System
IHV80_RS12440	COG1609	Transcriptional regulator
IHV80_RS12450	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
IHV80_RS12455	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IHV80_RS12460	COG2011	ABC-type metal ion transport system permease component
IHV80_RS12465	COG1464	Belongs to the NlpA lipoprotein family
IHV80_RS12470	COG4580	involved in the transport of maltose and maltodextrins
IHV80_RS12475	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
IHV80_RS12510	COG2885	chlorophyll binding
IHV80_RS12525	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
IHV80_RS12525	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
IHV80_RS12540	COG1611	Belongs to the LOG family
IHV80_RS12545	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IHV80_RS12555	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
IHV80_RS12570	COG0583	DNA-binding transcription factor activity
IHV80_RS12575	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IHV80_RS12575	COG0301	tRNA thio-modification
IHV80_RS12585	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
IHV80_RS12590	COG1722	exodeoxyribonuclease VII activity
IHV80_RS12595	COG0142	geranyltranstransferase activity
IHV80_RS12600	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IHV80_RS12610	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
IHV80_RS12615	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
IHV80_RS12620	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IHV80_RS12640	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IHV80_RS12640	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IHV80_RS12645	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IHV80_RS12650	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IHV80_RS12665	COG1073	alpha beta
IHV80_RS12670	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
IHV80_RS12675	COG2252	PERMEase
IHV80_RS12680	COG2195	Cleaves the N-terminal amino acid of tripeptides
IHV80_RS12700	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IHV80_RS12715	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IHV80_RS12730	COG1609	Transcriptional regulator
IHV80_RS12735	COG2017	converts alpha-aldose to the beta-anomer
IHV80_RS12745	COG1085	galactose-1-phosphate uridylyltransferase
IHV80_RS12750	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IHV80_RS12755	COG1609	Transcriptional regulator
IHV80_RS12760	COG3250	beta-galactosidase activity
IHV80_RS12765	COG2731	YhcH YjgK YiaL family protein
IHV80_RS12770	COG0531	amino acid
IHV80_RS12775	COG0531	amino acid
IHV80_RS12785	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
IHV80_RS12785	COG3408	Glycogen debranching enzyme
IHV80_RS12790	COG0534	Mate efflux family protein
IHV80_RS12800	COG0583	DNA-binding transcription factor activity
IHV80_RS12805	COG2059	Chromate
IHV80_RS12870	COG4964	Belongs to the GSP D family
IHV80_RS12900	COG1022	Amp-dependent synthetase and ligase
IHV80_RS12910	COG0583	DNA-binding transcription factor activity
IHV80_RS12920	COG0583	DNA-binding transcription factor activity
IHV80_RS12925	COG4628	conserved protein (DUF2132)
IHV80_RS12930	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IHV80_RS12935	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IHV80_RS12945	COG0560	Phosphoserine phosphatase
IHV80_RS12955	COG0813	purine-nucleoside phosphorylase activity
IHV80_RS12965	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
IHV80_RS12970	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
IHV80_RS12975	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IHV80_RS12980	COG0084	hydrolase, TatD family'
IHV80_RS12990	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
IHV80_RS13010	COG3154	lipid carrier protein
IHV80_RS13020	COG0826	peptidase U32
IHV80_RS13025	COG0826	peptidase U32
IHV80_RS13030	COG0534	Mate efflux family protein
IHV80_RS13045	COG1185	polyribonucleotide nucleotidyltransferase activity
IHV80_RS13050	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IHV80_RS13055	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IHV80_RS13060	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IHV80_RS13065	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IHV80_RS13070	COG0195	Participates in both transcription termination and antitermination
IHV80_RS13075	COG0779	Required for maturation of 30S ribosomal subunits
IHV80_RS13090	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
IHV80_RS13095	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IHV80_RS13100	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IHV80_RS13105	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IHV80_RS13110	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
IHV80_RS13115	COG1534	Rna-binding protein
IHV80_RS13120	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IHV80_RS13130	COG2027	D-alanyl-D-alanine carboxypeptidase
IHV80_RS13135	COG2239	Acts as a magnesium transporter
IHV80_RS13140	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IHV80_RS13145	COG0739	heme binding
IHV80_RS13160	COG0316	Belongs to the HesB IscA family
IHV80_RS13165	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
IHV80_RS13170	COG0628	permease
IHV80_RS13185	COG0747	negative chemotaxis
IHV80_RS13195	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IHV80_RS13200	COG0444	Belongs to the ABC transporter superfamily
IHV80_RS13205	COG4608	Belongs to the ABC transporter superfamily
IHV80_RS13215	COG2971	BadF BadG BcrA BcrD
IHV80_RS13230	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IHV80_RS13235	COG3842	ATPase activity
IHV80_RS13245	COG1840	ABC-type Fe3 transport system, periplasmic component
IHV80_RS13250	COG0004	ammonium transporteR
IHV80_RS13265	COG1049	propionate catabolic process, 2-methylcitrate cycle
IHV80_RS13270	COG1752	Esterase of the alpha-beta hydrolase superfamily
IHV80_RS13275	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IHV80_RS13280	COG1643	Atp-dependent helicase
IHV80_RS13285	COG1489	DNA binding
IHV80_RS13305	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IHV80_RS13310	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
IHV80_RS13315	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
IHV80_RS13320	COG0842	Transport permease protein
IHV80_RS13325	COG1131	(ABC) transporter
IHV80_RS13330	COG0659	secondary active sulfate transmembrane transporter activity
IHV80_RS13335	COG0288	reversible hydration of carbon dioxide
IHV80_RS13350	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IHV80_RS13355	COG0508	dehydrogenase complex catalyzes the overall conversion of
IHV80_RS13360	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
IHV80_RS13365	COG2186	Transcriptional regulator
IHV80_RS13375	COG0157	Belongs to the NadC ModD family
IHV80_RS13385	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IHV80_RS13390	COG1459	type II secretion system
IHV80_RS13400	COG0237	dephospho-CoA kinase activity
IHV80_RS13405	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
IHV80_RS13415	COG0335	large ribosomal subunit rRNA binding
IHV80_RS13420	COG0336	Belongs to the RNA methyltransferase TrmD family
IHV80_RS13425	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IHV80_RS13430	COG0228	four-way junction DNA binding
IHV80_RS13435	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IHV80_RS13440	COG4137	Cytochrome C assembly protein
IHV80_RS13445	COG4536	flavin adenine dinucleotide binding
IHV80_RS13450	COG1854	S-ribosylhomocysteine lyase activity
IHV80_RS13460	COG2918	glutathione biosynthetic process
IHV80_RS13465	COG0612	Peptidase, M16
IHV80_RS13470	COG1238	metal cluster binding
IHV80_RS13480	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
IHV80_RS13550	COG0527	aspartate kinase activity
IHV80_RS13560	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IHV80_RS13565	COG1546	Belongs to the CinA family
IHV80_RS13600	COG0732	type I restriction modification DNA specificity domain
IHV80_RS13605	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
IHV80_RS13610	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
IHV80_RS13645	COG2003	Belongs to the UPF0758 family
IHV80_RS13685	COG0328	RNA-DNA hybrid ribonuclease activity
IHV80_RS13720	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IHV80_RS13725	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IHV80_RS13735	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
IHV80_RS13740	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
IHV80_RS13745	COG0585	pseudouridine synthase activity
IHV80_RS13755	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
IHV80_RS13760	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
IHV80_RS13765	COG0148	phosphopyruvate hydratase activity
IHV80_RS13770	COG0504	CTP synthase activity
IHV80_RS13775	COG3956	TIGRFAM MazG family protein
IHV80_RS13780	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IHV80_RS13785	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IHV80_RS13790	COG2205	protein histidine kinase activity
IHV80_RS13790	COG3437	response regulator, receiver
IHV80_RS13790	COG4999	Histidine kinase
IHV80_RS13790	COG3850	Histidine kinase
IHV80_RS13795	COG0736	holo-[acyl-carrier-protein] synthase activity
IHV80_RS13800	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
IHV80_RS13805	COG1381	Involved in DNA repair and RecF pathway recombination
IHV80_RS13810	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IHV80_RS13815	COG0571	ribonuclease III activity
IHV80_RS13825	COG0481	GTPase activity
IHV80_RS13845	COG1595	DNA-templated transcription, initiation
IHV80_RS13850	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
IHV80_RS13860	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
IHV80_RS13865	COG0354	folic acid binding
IHV80_RS13880	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IHV80_RS13885	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IHV80_RS13890	COG3079	Belongs to the UPF0149 family
IHV80_RS13895	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
IHV80_RS13905	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IHV80_RS13910	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
IHV80_RS13915	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IHV80_RS13930	COG1279	arginine transmembrane transporter activity
IHV80_RS13940	COG0668	transmembrane transport
IHV80_RS13945	COG0191	fructose-bisphosphate aldolase activity
IHV80_RS13960	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IHV80_RS13965	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IHV80_RS13975	COG3091	SprT-like family
IHV80_RS13980	COG2356	endonuclease I
IHV80_RS13985	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IHV80_RS13990	COG0189	ligase activity
IHV80_RS13995	COG1678	Uncharacterized ACR, COG1678
IHV80_RS14000	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IHV80_RS14015	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IHV80_RS14020	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IHV80_RS14025	COG0762	integral membrane protein
IHV80_RS14040	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IHV80_RS14045	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IHV80_RS14050	COG2066	Belongs to the glutaminase family
IHV80_RS14065	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
IHV80_RS14070	COG0741	lytic transglycosylase activity
IHV80_RS14110	COG0840	transmembrane signaling receptor activity
IHV80_RS14220	COG0795	lipopolysaccharide-transporting ATPase activity
IHV80_RS14225	COG0795	lipopolysaccharide-transporting ATPase activity
IHV80_RS14230	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IHV80_RS14235	COG2927	DNA polymerase III (CHI subunit)
IHV80_RS14240	COG0525	valine-tRNA ligase activity
IHV80_RS14250	COG4269	membrane
IHV80_RS14260	COG0456	acetyltransferase
IHV80_RS14290	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
IHV80_RS14295	COG0251	oxidation-reduction process
IHV80_RS14300	COG0204	Acyl-transferase
IHV80_RS14305	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IHV80_RS14310	COG5007	Belongs to the BolA IbaG family
IHV80_RS14320	COG2854	intermembrane phospholipid transfer
IHV80_RS14325	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IHV80_RS14330	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IHV80_RS14335	COG1127	ABC transporter
IHV80_RS14345	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
IHV80_RS14345	COG0517	IMP dehydrogenase activity
IHV80_RS14350	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
IHV80_RS14360	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
IHV80_RS14365	COG1137	ATPase activity
IHV80_RS14375	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IHV80_RS14380	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IHV80_RS14385	COG1660	Displays ATPase and GTPase activities
IHV80_RS14390	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IHV80_RS14395	COG2239	Acts as a magnesium transporter
IHV80_RS14400	COG0312	modulator of DNA gyrase
IHV80_RS14405	COG3028	Belongs to the UPF0307 family
IHV80_RS14410	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
IHV80_RS14415	COG1178	ABC-type Fe3 transport system permease component
IHV80_RS14420	COG4143	(ABC) transporter
IHV80_RS14425	COG0163	prenyltransferase activity
IHV80_RS14430	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IHV80_RS14435	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
IHV80_RS14445	COG2105	PFAM AIG2 family protein
IHV80_RS14450	COG2911	Protein conserved in bacteria
IHV80_RS14455	COG0729	surface antigen
IHV80_RS14460	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IHV80_RS14470	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
IHV80_RS14505	COG0529	Catalyzes the synthesis of activated sulfate
IHV80_RS14510	COG0471	metal ion transport
IHV80_RS14510	COG3273	potassium ion transport
IHV80_RS14515	COG2895	sulfate adenylyltransferase (ATP) activity
IHV80_RS14520	COG0175	sulfate reduction
IHV80_RS14525	COG0737	Belongs to the 5'-nucleotidase family
IHV80_RS14570	COG2153	protein acetylation
IHV80_RS14580	COG3266	domain, Protein
IHV80_RS14580	COG3061	Opacity-associated protein A
IHV80_RS14585	COG0545	Peptidyl-prolyl cis-trans isomerase
IHV80_RS14595	COG0203	ribosomal protein L17
IHV80_RS14600	COG0202	RNA polymerase activity
IHV80_RS14605	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IHV80_RS14610	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IHV80_RS14615	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IHV80_RS14620	COG0257	Belongs to the bacterial ribosomal protein bL36 family
IHV80_RS14625	COG0201	protein transport
IHV80_RS14630	COG0200	Binds to the 23S rRNA
IHV80_RS14635	COG1841	ribosomal large subunit assembly
IHV80_RS14640	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IHV80_RS14650	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IHV80_RS14655	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IHV80_RS14660	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IHV80_RS14665	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IHV80_RS14670	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IHV80_RS14675	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IHV80_RS14680	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IHV80_RS14690	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IHV80_RS14695	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IHV80_RS14705	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IHV80_RS14710	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IHV80_RS14715	COG0089	rRNA binding
IHV80_RS14720	COG0088	Forms part of the polypeptide exit tunnel
IHV80_RS14725	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IHV80_RS14740	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IHV80_RS14745	COG0049	tRNA binding
IHV80_RS14750	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IHV80_RS14760	COG2923	Belongs to the DsrF TusC family
IHV80_RS14765	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
IHV80_RS14770	COG2964	Protein conserved in bacteria
IHV80_RS14775	COG0545	Peptidyl-prolyl cis-trans isomerase
IHV80_RS14785	COG2900	Belongs to the SlyX family
IHV80_RS14790	COG1446	asparaginase
IHV80_RS14795	COG1047	Peptidyl-prolyl cis-trans
IHV80_RS14810	COG2249	NAD(P)H dehydrogenase (quinone) activity
IHV80_RS14815	COG0488	(ABC) transporter
IHV80_RS14825	COG0429	hydrolase of the alpha beta-hydrolase fold
IHV80_RS14830	COG3089	Belongs to the UPF0270 family
IHV80_RS14835	COG3954	Phosphoribulokinase
IHV80_RS14840	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IHV80_RS14850	COG1012	belongs to the aldehyde dehydrogenase family
IHV80_RS14860	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IHV80_RS14865	COG0512	Glutamine amidotransferase of anthranilate synthase
IHV80_RS14875	COG0180	Tryptophanyl-tRNA synthetase
IHV80_RS14880	COG0546	phosphoglycolate phosphatase activity
IHV80_RS14885	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
IHV80_RS14890	COG0338	D12 class N6 adenine-specific DNA methyltransferase
IHV80_RS14900	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IHV80_RS14935	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
IHV80_RS14945	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IHV80_RS14945	COG0678	peroxiredoxin activity
IHV80_RS14950	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IHV80_RS14955	COG0251	oxidation-reduction process
IHV80_RS14965	COG0165	Argininosuccinate lyase
IHV80_RS14965	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
IHV80_RS14980	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IHV80_RS14985	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IHV80_RS14990	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
IHV80_RS15000	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
IHV80_RS15005	COG0460	homoserine dehydrogenase
IHV80_RS15005	COG0527	aspartate kinase activity
IHV80_RS15010	COG0626	cystathionine gamma-synthase activity
IHV80_RS15015	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
IHV80_RS15020	COG0281	malic enzyme
IHV80_RS15025	COG0254	rRNA binding
IHV80_RS15030	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IHV80_RS15035	COG1609	Transcriptional regulator
IHV80_RS15040	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
IHV80_RS15045	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
IHV80_RS15050	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
IHV80_RS15055	COG1575	Belongs to the MenA family. Type 1 subfamily
IHV80_RS15060	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IHV80_RS15065	COG3074	FtsZ-dependent cytokinesis
IHV80_RS15070	COG1494	fructose-1,6-bisphosphatase
IHV80_RS15075	COG3111	PFAM Bacterial OB fold (BOF) protein
IHV80_RS15095	COG3152	Membrane
IHV80_RS15115	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IHV80_RS15125	COG0745	RESPONSE REGULATOR receiver
IHV80_RS15130	COG2205	protein histidine kinase activity
IHV80_RS15140	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
IHV80_RS15150	COG1027	Aspartate ammonia-lyase
IHV80_RS15155	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
IHV80_RS15175	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IHV80_RS15180	COG0540	Belongs to the ATCase OTCase family
IHV80_RS15185	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
IHV80_RS15190	COG1438	arginine binding
IHV80_RS15195	COG4232	protein-disulfide reductase activity
IHV80_RS15205	COG3263	regulation of cellular component size
IHV80_RS15215	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IHV80_RS15230	COG2198	Histidine kinase
IHV80_RS15230	COG2205	protein histidine kinase activity
IHV80_RS15230	COG0784	Response regulator, receiver
IHV80_RS15235	COG2814	Major facilitator Superfamily
IHV80_RS15250	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IHV80_RS15255	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
IHV80_RS15260	COG0511	ligase activity, forming carbon-carbon bonds
IHV80_RS15265	COG0439	Biotin carboxylase
IHV80_RS15270	COG2264	protein methyltransferase activity
IHV80_RS15275	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IHV80_RS15280	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
IHV80_RS15285	COG0789	Transcriptional regulator
IHV80_RS15290	COG0138	bifunctional purine biosynthesis protein purh
IHV80_RS15295	COG0151	Belongs to the GarS family
IHV80_RS15310	COG1253	flavin adenine dinucleotide binding
IHV80_RS15315	COG3068	Protein conserved in bacteria
IHV80_RS15325	COG1573	uracil-dna glycosylase
IHV80_RS15335	COG2816	NAD+ diphosphatase activity
IHV80_RS15340	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
IHV80_RS15355	COG0222	ribosome binding
IHV80_RS15360	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IHV80_RS15365	COG0081	regulation of translation
IHV80_RS15375	COG0250	Participates in transcription elongation, termination and antitermination
IHV80_RS15380	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
IHV80_RS15410	COG1072	(Pantothenic acid kinase))
IHV80_RS15420	COG0812	UDP-N-acetylmuramate dehydrogenase activity
IHV80_RS15430	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IHV80_RS15530	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
IHV80_RS15545	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IHV80_RS15560	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IHV80_RS15565	COG0534	Mate efflux family protein
IHV80_RS15570	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
IHV80_RS15575	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IHV80_RS15580	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
IHV80_RS15585	COG2937	Belongs to the GPAT DAPAT family
IHV80_RS15590	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
IHV80_RS15595	COG3161	chorismate lyase activity
IHV80_RS15600	COG1580	Controls the rotational direction of flagella during chemotaxis
IHV80_RS15610	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IHV80_RS15620	COG2177	Part of the ABC transporter FtsEX involved in
IHV80_RS15625	COG2884	Cell division ATP-binding protein ftsE
IHV80_RS15630	COG0552	protein localization to endoplasmic reticulum
IHV80_RS15630	COG0552	protein localization to endoplasmic reticulum
IHV80_RS15635	COG0742	ribosomal rna small subunit methyltransferase
IHV80_RS15645	COG2095	MarC family integral membrane protein
IHV80_RS15685	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IHV80_RS15690	COG0640	Transcriptional regulator
IHV80_RS15695	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
IHV80_RS15700	COG1280	lysine exporter protein (LysE YggA)
IHV80_RS15705	COG2267	carboxylic ester hydrolase activity
IHV80_RS15710	COG0561	phosphatase activity
IHV80_RS15725	COG3148	PFAM DTW domain containing protein
IHV80_RS15730	COG2200	EAL domain
IHV80_RS15730	COG2199	diguanylate cyclase activity
IHV80_RS15730	COG3287	FIST C domain
IHV80_RS15735	COG2199	diguanylate cyclase activity
IHV80_RS15735	COG2200	EAL domain
IHV80_RS15735	COG3287	FIST C domain
IHV80_RS15740	COG1011	Hydrolase
IHV80_RS15745	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
IHV80_RS15755	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
IHV80_RS15760	COG0019	diaminopimelate decarboxylase activity
IHV80_RS15770	COG1965	Belongs to the frataxin family
IHV80_RS15780	COG0181	hydroxymethylbilane synthase activity
IHV80_RS15785	COG1587	Uroporphyrinogen-III synthase
IHV80_RS15790	COG2959	enzyme of heme biosynthesis
IHV80_RS15795	COG3071	HemY protein
IHV80_RS15855	COG2871	sodium ion transport
IHV80_RS15860	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
IHV80_RS15875	COG3118	belongs to the thioredoxin family
IHV80_RS15880	COG0513	Belongs to the DEAD box helicase family
IHV80_RS15885	COG0248	Ppx GppA phosphatase
IHV80_RS15895	COG0861	Integral membrane protein TerC family
IHV80_RS15905	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
IHV80_RS15915	COG0514	ATP-dependent DNA helicase (RecQ)
IHV80_RS15920	COG2962	Rard protein
IHV80_RS15930	COG1280	lysine exporter protein (LysE YggA)
IHV80_RS15935	COG0405	Gamma-glutamyltransferase
IHV80_RS15945	COG0210	DNA helicase
IHV80_RS15955	COG3220	belongs to the UPF0276 family
IHV80_RS15985	COG0006	proline dipeptidase activity
IHV80_RS15985	COG0006	proline dipeptidase activity
IHV80_RS15995	COG2022	thiamine diphosphate biosynthetic process
IHV80_RS16000	COG2104	thiamine diphosphate biosynthetic process
IHV80_RS16005	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
IHV80_RS16010	COG0352	thiamine-phosphate diphosphorylase activity
IHV80_RS16015	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
IHV80_RS16025	COG2132	Multicopper oxidase
IHV80_RS16070	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IHV80_RS16080	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IHV80_RS16085	COG0408	coproporphyrinogen oxidase activity
IHV80_RS16090	COG0009	L-threonylcarbamoyladenylate synthase
IHV80_RS16095	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IHV80_RS16100	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IHV80_RS16105	COG0551	DNA topoisomerase type I activity
IHV80_RS16110	COG2922	Belongs to the Smg family
IHV80_RS16115	COG0758	DNA mediated transformation
IHV80_RS16125	COG0242	peptide deformylase activity
IHV80_RS16130	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IHV80_RS16135	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IHV80_RS16135	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IHV80_RS16140	COG0569	domain protein
IHV80_RS16145	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IHV80_RS16155	COG1272	protein, Hemolysin III
IHV80_RS16160	COG4326	sporulation control protein
IHV80_RS16170	COG3084	Protein conserved in bacteria
IHV80_RS16190	COG1876	peptidase activity
IHV80_RS16290	COG4974	Belongs to the 'phage' integrase family
IHV80_RS16295	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IHV80_RS16300	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IHV80_RS16315	COG0606	chelatase, subunit chli
IHV80_RS16325	COG3978	acetolactate synthase activity
IHV80_RS16330	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IHV80_RS16335	COG0129	dihydroxy-acid dehydratase activity
IHV80_RS16345	COG0583	DNA-binding transcription factor activity
IHV80_RS16350	COG2814	Major facilitator Superfamily
IHV80_RS16355	COG3706	GGDEF domain
IHV80_RS16365	COG0355	proton-transporting ATP synthase activity, rotational mechanism
IHV80_RS16370	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IHV80_RS16375	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IHV80_RS16380	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IHV80_RS16385	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IHV80_RS16390	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IHV80_RS16405	COG3312	ion transport
IHV80_RS16410	COG1475	DNA binding
IHV80_RS16415	COG1192	Involved in chromosome partitioning
IHV80_RS16420	COG0357	Ribosomal RNA small subunit methyltransferase G
IHV80_RS16425	COG0445	tRNA wobble uridine modification
IHV80_RS16430	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IHV80_RS16440	COG0706	membrane insertase activity
IHV80_RS16445	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
IHV80_RS16450	COG0594	ribonuclease P activity
IHV80_RS16455	COG0230	Belongs to the bacterial ribosomal protein bL34 family
IHV80_RS16460	COG1126	abc transporter atp-binding protein
IHV80_RS16480	COG0583	DNA-binding transcription factor activity
IHV80_RS16485	COG1620	l-lactate permease
IHV80_RS16490	COG1304	FMN binding
IHV80_RS16505	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IHV80_RS16505	COG2207	Transcriptional regulator
IHV80_RS16510	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IHV80_RS16525	COG2015	COG2015, Alkyl sulfatase and related hydrolases
IHV80_RS16535	COG1054	Belongs to the UPF0176 family
IHV80_RS16545	COG5002	protein histidine kinase activity
IHV80_RS16550	COG0745	RESPONSE REGULATOR receiver
IHV80_RS16570	COG1482	cell wall glycoprotein biosynthetic process
IHV80_RS16575	COG2271	Major facilitator Superfamily
IHV80_RS16580	COG3851	Histidine kinase
IHV80_RS16585	COG2197	response regulator
IHV80_RS16620	COG1741	Belongs to the pirin family
IHV80_RS16625	COG3123	guanosine phosphorylase activity
IHV80_RS16640	COG0596	Alpha beta hydrolase
IHV80_RS16685	COG3788	relative of glutathione S-transferase, MAPEG superfamily
IHV80_RS16690	COG0700	Nucleoside recognition
IHV80_RS16695	COG3366	ferrous iron transmembrane transporter activity
IHV80_RS16705	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IHV80_RS16720	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
IHV80_RS16740	COG0363	glucosamine-6-phosphate deaminase activity
IHV80_RS16745	COG3722	fumarate hydratase activity
IHV80_RS16750	COG0246	Mannitol dehydrogenase
IHV80_RS16755	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
IHV80_RS16755	COG2213	PTS system mannitol-specific
IHV80_RS16775	COG0446	pyridine nucleotide-disulphide oxidoreductase
IHV80_RS16780	COG0786	glutamate:sodium symporter activity
IHV80_RS16795	COG1942	4-Oxalocrotonate Tautomerase
IHV80_RS16805	COG1595	DNA-templated transcription, initiation
IHV80_RS16810	COG3806	Anti-sigma factor
IHV80_RS16820	COG0415	Belongs to the DNA photolyase family
IHV80_RS16845	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IHV80_RS16870	COG4221	oxidoreductase activity
IHV80_RS16875	COG0724	RNA recognition motif
IHV80_RS16885	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
IHV80_RS16900	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IHV80_RS16900	COG1263	PTS System
IHV80_RS16905	COG2205	protein histidine kinase activity
IHV80_RS16925	COG2814	Major facilitator Superfamily
IHV80_RS16930	COG1902	pentaerythritol trinitrate reductase activity
IHV80_RS16945	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IHV80_RS16950	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IHV80_RS16960	COG0612	Peptidase, M16
IHV80_RS16965	COG3279	Response regulator of the LytR AlgR family
IHV80_RS16970	COG3275	phosphorelay sensor kinase activity
IHV80_RS16985	COG4591	ABC-type transport system involved in lipoprotein release permease component
IHV80_RS17020	COG0753	catalase activity
IHV80_RS17025	COG2084	Dehydrogenase
IHV80_RS17040	COG0217	transcriptional regulatory protein
IHV80_RS17055	COG3186	Phenylalanine-4-hydroxylase
IHV80_RS17060	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IHV80_RS17070	COG0625	glutathione transferase activity
IHV80_RS17080	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
IHV80_RS17095	COG3842	ATPase activity
IHV80_RS17135	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IHV80_RS17135	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
IHV80_RS17145	COG0444	Belongs to the ABC transporter superfamily
IHV80_RS17150	COG4608	Belongs to the ABC transporter superfamily
IHV80_RS17180	COG1444	tRNA N-acetyltransferase activity
IHV80_RS17220	COG0259	pyridoxamine-phosphate oxidase activity
IHV80_RS17255	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IHV80_RS17285	COG4399	Belongs to the UPF0754 family
IHV80_RS17290	COG1132	(ABC) transporter
IHV80_RS17315	COG2194	sulfuric ester hydrolase activity
IHV80_RS17345	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
IHV80_RS17355	COG4145	pantothenate transmembrane transporter activity
IHV80_RS17360	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IHV80_RS17365	COG0800	Aldolase
IHV80_RS17385	COG2204	response regulator
IHV80_RS17400	COG0579	oxidoreductase
IHV80_RS17420	COG2205	protein histidine kinase activity
IHV80_RS17425	COG0745	RESPONSE REGULATOR receiver
IHV80_RS17440	COG1522	sequence-specific DNA binding
IHV80_RS17450	COG1473	amidohydrolase
IHV80_RS17455	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IHV80_RS17465	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
IHV80_RS17475	COG1309	transcriptional regulator
IHV80_RS17480	COG1012	belongs to the aldehyde dehydrogenase family
IHV80_RS17500	COG4175	Glycine betaine
IHV80_RS17505	COG1846	Transcriptional regulator
IHV80_RS17535	COG0641	radical SAM
IHV80_RS17540	COG1309	transcriptional regulator
IHV80_RS17550	COG0456	acetyltransferase
IHV80_RS17570	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
IHV80_RS17575	COG2211	Major facilitator Superfamily
IHV80_RS17580	COG1486	melibiose metabolic process
IHV80_RS17585	COG2169	Transcriptional regulator
IHV80_RS17590	COG3408	Glycogen debranching enzyme
IHV80_RS17590	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
IHV80_RS17605	COG2207	Transcriptional regulator
IHV80_RS17625	COG0110	maltose O-acetyltransferase activity
IHV80_RS17630	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IHV80_RS17650	COG0800	Aldolase
IHV80_RS17655	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IHV80_RS17660	COG1904	glucuronate isomerase
IHV80_RS17665	COG0246	Mannitol dehydrogenase
IHV80_RS17675	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
IHV80_RS17685	COG2186	Transcriptional regulator
IHV80_RS17690	COG1312	Catalyzes the dehydration of D-mannonate
IHV80_RS17695	COG2207	Transcriptional regulator
IHV80_RS17700	COG2814	Major facilitator Superfamily
IHV80_RS17710	COG1028	Short-chain dehydrogenase reductase Sdr
IHV80_RS17710	COG0604	alcohol dehydrogenase
IHV80_RS17710	COG3321	synthase
IHV80_RS17735	COG1410	methionine synthase
IHV80_RS17735	COG0646	methionine synthase
IHV80_RS17745	COG1028	Short-chain dehydrogenase reductase Sdr
IHV80_RS17800	COG0583	DNA-binding transcription factor activity
IHV80_RS17810	COG1288	antiporter activity
IHV80_RS17820	COG2015	COG2015, Alkyl sulfatase and related hydrolases
IHV80_RS17835	COG0346	lactoylglutathione lyase activity
IHV80_RS17850	COG3300	MHYT domain
IHV80_RS17850	COG5001	Diguanylate cyclase
IHV80_RS17875	COG0737	Belongs to the 5'-nucleotidase family
IHV80_RS17880	COG2723	6-phospho-beta-galactosidase activity
IHV80_RS17885	COG1609	Transcriptional regulator
IHV80_RS17890	COG0110	maltose O-acetyltransferase activity
IHV80_RS17895	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
IHV80_RS17900	COG1301	dicarboxylic acid transport
IHV80_RS17910	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IHV80_RS17920	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IHV80_RS17935	COG0549	Belongs to the carbamate kinase family
IHV80_RS17940	COG0531	amino acid
IHV80_RS17945	COG2957	Belongs to the agmatine deiminase family
IHV80_RS17960	COG1794	racemase activity, acting on amino acids and derivatives
IHV80_RS17970	COG0561	phosphatase activity
IHV80_RS17980	COG1454	alcohol dehydrogenase
IHV80_RS17985	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IHV80_RS17995	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IHV80_RS18005	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IHV80_RS18010	COG1263	PTS System
IHV80_RS18010	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IHV80_RS18025	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
IHV80_RS18030	COG1349	DNA-binding transcription factor activity
IHV80_RS18035	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IHV80_RS18040	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
IHV80_RS18055	COG2274	protein secretion by the type I secretion system
IHV80_RS18065	COG2994	toxin metabolic process
IHV80_RS18070	COG1073	alpha beta
IHV80_RS18070	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
IHV80_RS18070	COG3064	Membrane
IHV80_RS18080	COG0583	DNA-binding transcription factor activity
IHV80_RS18085	COG0798	PFAM Bile acid sodium symporter
IHV80_RS18105	COG0561	phosphatase activity
IHV80_RS18120	COG0583	DNA-binding transcription factor activity
IHV80_RS18155	COG1349	DNA-binding transcription factor activity
IHV80_RS18160	COG2084	Dehydrogenase
IHV80_RS18165	COG3395	kinase activity
IHV80_RS18170	COG0235	Class ii aldolase
IHV80_RS18175	COG3622	Belongs to the hyi family
IHV80_RS18180	COG2610	gluconate transmembrane transporter activity
IHV80_RS18185	COG1929	Belongs to the glycerate kinase type-1 family
IHV80_RS18190	COG0753	catalase activity
IHV80_RS18195	COG4667	esterase of the alpha-beta hydrolase superfamily
IHV80_RS18200	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IHV80_RS18205	COG3615	Tellurite resistance protein tehB
IHV80_RS18210	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IHV80_RS18215	COG0204	Acyl-transferase
IHV80_RS18220	COG2384	SAM-dependent methyltransferase
IHV80_RS18235	COG4580	involved in the transport of maltose and maltodextrins
IHV80_RS18250	COG1523	belongs to the glycosyl hydrolase 13 family
IHV80_RS18270	COG0583	DNA-binding transcription factor activity
IHV80_RS18280	COG1053	succinate dehydrogenase
IHV80_RS18280	COG3976	FMN-binding domain protein
IHV80_RS18295	COG3258	Cytochrome c
IHV80_RS18300	COG2863	cytochrome
IHV80_RS18325	COG4566	intracellular signal transduction
IHV80_RS18335	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
IHV80_RS18340	COG1162	GTPase activity
IHV80_RS18350	COG1999	signal sequence binding
IHV80_RS18365	COG2909	trisaccharide binding
IHV80_RS18370	COG0058	SHG alpha-glucan phosphorylase activity
IHV80_RS18375	COG1640	4-alpha-glucanotransferase
IHV80_RS18380	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
IHV80_RS18395	COG1122	ATPase activity
IHV80_RS18400	COG4720	Psort location CytoplasmicMembrane, score
IHV80_RS18410	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
IHV80_RS18415	COG1757	Na H antiporter
IHV80_RS18425	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IHV80_RS18430	COG0697	spore germination
IHV80_RS18450	COG0840	transmembrane signaling receptor activity
IHV80_RS18460	COG0583	DNA-binding transcription factor activity
IHV80_RS18485	COG0583	DNA-binding transcription factor activity
IHV80_RS18495	COG4948	Mandelate Racemase Muconate Lactonizing
IHV80_RS18520	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
IHV80_RS18525	COG3639	organic phosphonate transmembrane transporter activity
IHV80_RS18530	COG3639	organic phosphonate transmembrane transporter activity
IHV80_RS18550	COG1288	antiporter activity
IHV80_RS18555	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
IHV80_RS18560	COG3047	cAMP biosynthetic process
IHV80_RS18570	COG4221	oxidoreductase activity
IHV80_RS18575	COG0583	DNA-binding transcription factor activity
IHV80_RS18580	COG1733	regulation of RNA biosynthetic process
IHV80_RS18585	COG1028	Short-chain dehydrogenase reductase Sdr
IHV80_RS18600	COG0583	DNA-binding transcription factor activity
IHV80_RS18640	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IHV80_RS18650	COG1741	Belongs to the pirin family
IHV80_RS18655	COG1335	isochorismatase
IHV80_RS18685	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IHV80_RS18690	COG1595	DNA-templated transcription, initiation
IHV80_RS18710	COG1901	pseudouridine methyltransferase
IHV80_RS18760	COG0446	pyridine nucleotide-disulphide oxidoreductase
IHV80_RS18770	COG0251	oxidation-reduction process
IHV80_RS18775	COG2964	Protein conserved in bacteria
IHV80_RS18785	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
IHV80_RS18790	COG3639	organic phosphonate transmembrane transporter activity
IHV80_RS18795	COG2188	Transcriptional regulator
IHV80_RS18800	COG3624	Phosphonate C-P lyase system protein PhnG
IHV80_RS18805	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
IHV80_RS18810	COG3626	phosphonate metabolism
IHV80_RS18815	COG3627	carbon phosphorus lyase activity
IHV80_RS18820	COG4107	phosphonate C-P lyase system protein PhnK
IHV80_RS18825	COG4778	phosphonate C-P lyase system protein PhnL
IHV80_RS18830	COG3454	Phosphonate metabolism
IHV80_RS18840	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
IHV80_RS18845	COG0110	maltose O-acetyltransferase activity
IHV80_RS18850	COG0534	Mate efflux family protein
IHV80_RS18865	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
IHV80_RS18870	COG0543	2 iron, 2 sulfur cluster binding
IHV80_RS18870	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IHV80_RS18875	COG2999	glutathione oxidoreductase activity
IHV80_RS18885	COG0673	inositol 2-dehydrogenase activity
IHV80_RS18905	COG0584	glycerophosphoryl diester phosphodiesterase
IHV80_RS18925	COG0189	ligase activity
IHV80_RS18925	COG4067	protein conserved in archaea
IHV80_RS18930	COG0189	ligase activity
IHV80_RS18935	COG4533	DNA binding
IHV80_RS18940	COG0840	transmembrane signaling receptor activity
IHV80_RS18990	COG2814	Major facilitator Superfamily
IHV80_RS19000	COG0564	pseudouridine synthase activity
IHV80_RS19010	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IHV80_RS19010	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IHV80_RS19030	COG1131	(ABC) transporter
IHV80_RS19035	COG2186	Transcriptional regulator
IHV80_RS19055	COG5001	Diguanylate cyclase
IHV80_RS19070	COG2205	protein histidine kinase activity
IHV80_RS19080	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
IHV80_RS19085	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IHV80_RS19090	COG3037	sugar-specific permease SgaT UlaA
IHV80_RS19105	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IHV80_RS19115	COG4106	trans-aconitate 2-methyltransferase activity
IHV80_RS19130	COG0513	Belongs to the DEAD box helicase family
IHV80_RS19145	COG3706	GGDEF domain
IHV80_RS19150	COG1278	Cold shock
IHV80_RS19155	COG0402	S-adenosylhomocysteine deaminase activity
IHV80_RS19160	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
IHV80_RS19175	COG2207	Transcriptional regulator
IHV80_RS19180	COG4413	Urea transporter
IHV80_RS19195	COG0531	amino acid
IHV80_RS19210	COG1280	lysine exporter protein (LysE YggA)
IHV80_RS19225	COG1151	hydroxylamine reductase activity
IHV80_RS19230	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IHV80_RS19240	COG5002	protein histidine kinase activity
IHV80_RS19240	COG0784	Response regulator, receiver
IHV80_RS19240	COG2205	protein histidine kinase activity
IHV80_RS19255	COG2926	Belongs to the UPF0265 family
IHV80_RS19265	COG3132	Protein of unknown function, DUF480
IHV80_RS19270	COG2827	Endonuclease containing a URI domain
IHV80_RS19300	COG0443	Heat shock 70 kDa protein
IHV80_RS19310	COG0179	Fumarylacetoacetate (FAA) hydrolase
IHV80_RS19315	COG1280	lysine exporter protein (LysE YggA)
IHV80_RS19320	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IHV80_RS19325	COG1565	acr, cog1565
IHV80_RS19325	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
IHV80_RS19330	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IHV80_RS19340	COG1845	cytochrome c oxidase, subunit III
IHV80_RS19365	COG0109	protoheme IX farnesyltransferase activity
IHV80_RS19385	COG3530	Putative quorum-sensing-regulated virulence factor
IHV80_RS19390	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IHV80_RS19410	COG0668	transmembrane transport
IHV80_RS19415	COG0569	domain protein
IHV80_RS19420	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IHV80_RS19430	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IHV80_RS19430	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IHV80_RS19435	COG1765	OsmC-like protein
IHV80_RS19440	COG2885	chlorophyll binding
IHV80_RS19450	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IHV80_RS19460	COG1840	ABC-type Fe3 transport system, periplasmic component
IHV80_RS19465	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IHV80_RS19475	COG3842	ATPase activity
IHV80_RS19495	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
IHV80_RS19505	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
IHV80_RS19510	COG3265	gluconokinase activity
IHV80_RS19515	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IHV80_RS19520	COG1609	Transcriptional regulator
IHV80_RS19525	COG2375	cellular response to nickel ion
IHV80_RS19530	COG3104	oligopeptide transport
IHV80_RS19535	COG1760	l-serine dehydratase
IHV80_RS19555	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IHV80_RS19560	COG1132	(ABC) transporter
IHV80_RS19565	COG1132	(ABC) transporter
IHV80_RS19590	COG0739	heme binding
IHV80_RS19595	COG0393	Putative heavy-metal-binding
IHV80_RS19610	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
IHV80_RS19615	COG3706	GGDEF domain
IHV80_RS19615	COG5001	Diguanylate cyclase
IHV80_RS19615	COG4251	negative regulation of phosphorylation
IHV80_RS19615	COG2203	Gaf domain
IHV80_RS19620	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
IHV80_RS19640	COG0346	lactoylglutathione lyase activity
IHV80_RS19660	COG2200	EAL domain
IHV80_RS19665	COG0156	8-amino-7-oxononanoate synthase activity
IHV80_RS19670	COG1063	alcohol dehydrogenase
IHV80_RS19700	COG2249	NAD(P)H dehydrogenase (quinone) activity
IHV80_RS19720	COG1454	alcohol dehydrogenase
IHV80_RS19730	COG1011	Hydrolase
IHV80_RS19760	COG1328	CTP reductase activity
IHV80_RS19765	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IHV80_RS19770	COG0583	DNA-binding transcription factor activity
IHV80_RS19790	COG1289	transmembrane transporter activity
IHV80_RS19795	COG0210	DNA helicase
IHV80_RS19805	COG1803	Methylglyoxal synthase
IHV80_RS19810	COG1879	ABC-type sugar transport system periplasmic component
IHV80_RS19815	COG3850	Histidine kinase
IHV80_RS19815	COG2205	protein histidine kinase activity
IHV80_RS19815	COG4999	Histidine kinase
IHV80_RS19815	COG3437	response regulator, receiver
IHV80_RS19850	COG0625	glutathione transferase activity
IHV80_RS19855	COG1252	NADH dehydrogenase
IHV80_RS19890	COG0745	RESPONSE REGULATOR receiver
IHV80_RS19915	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IHV80_RS19925	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IHV80_RS19925	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IHV80_RS19925	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
IHV80_RS19930	COG1105	Belongs to the carbohydrate kinase PfkB family
IHV80_RS19935	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
IHV80_RS19935	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IHV80_RS19940	COG1609	Transcriptional regulator
IHV80_RS19945	COG2815	serine threonine protein kinase
IHV80_RS19945	COG0515	serine threonine protein kinase
IHV80_RS19950	COG2223	nitrite transmembrane transporter activity
IHV80_RS19960	COG2146	nitrite reductase [NAD(P)H] activity
IHV80_RS19960	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IHV80_RS19965	COG0243	molybdopterin cofactor binding
IHV80_RS19980	COG0789	Transcriptional regulator
IHV80_RS19985	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IHV80_RS20005	COG0583	DNA-binding transcription factor activity
IHV80_RS20030	COG1609	Transcriptional regulator
IHV80_RS20035	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IHV80_RS20040	COG1879	ABC-type sugar transport system periplasmic component
IHV80_RS20045	COG1172	Belongs to the binding-protein-dependent transport system permease family
IHV80_RS20050	COG1129	ABC transporter
IHV80_RS20055	COG1869	D-ribose catabolic process
IHV80_RS20075	COG4166	transmembrane transport
IHV80_RS20080	COG4174	ABC transporter (Permease)
IHV80_RS20085	COG4239	(ABC) transporter, permease
IHV80_RS20090	COG4172	Belongs to the ABC transporter superfamily
IHV80_RS20110	COG3842	ATPase activity
IHV80_RS20115	COG0584	glycerophosphoryl diester phosphodiesterase
IHV80_RS20120	COG1940	carbohydrate kinase activity
IHV80_RS20130	COG4174	ABC transporter (Permease)
IHV80_RS20135	COG4239	(ABC) transporter, permease
IHV80_RS20140	COG4166	transmembrane transport
IHV80_RS20145	COG0444	Belongs to the ABC transporter superfamily
IHV80_RS20150	COG4608	Belongs to the ABC transporter superfamily
IHV80_RS20165	COG0745	RESPONSE REGULATOR receiver
IHV80_RS20170	COG0642	Histidine kinase
IHV80_RS20180	COG0583	DNA-binding transcription factor activity
IHV80_RS20190	COG0355	proton-transporting ATP synthase activity, rotational mechanism
IHV80_RS20200	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IHV80_RS20210	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IHV80_RS20225	COG0356	it plays a direct role in the translocation of protons across the membrane
IHV80_RS20235	COG0583	DNA-binding transcription factor activity
IHV80_RS20245	COG1012	belongs to the aldehyde dehydrogenase family
IHV80_RS20255	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IHV80_RS20300	COG3278	Belongs to the heme-copper respiratory oxidase family
IHV80_RS20320	COG3300	MHYT domain
IHV80_RS20320	COG5001	Diguanylate cyclase
IHV80_RS20330	COG1280	lysine exporter protein (LysE YggA)
IHV80_RS20335	COG0384	phenazine biosynthesis protein PhzF
IHV80_RS20350	COG0454	-acetyltransferase
IHV80_RS20365	COG0456	acetyltransferase
IHV80_RS20370	COG2197	response regulator
IHV80_RS20375	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IHV80_RS20390	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
IHV80_RS20395	COG0784	Response regulator, receiver
IHV80_RS20395	COG2205	protein histidine kinase activity
IHV80_RS20405	COG3119	arylsulfatase activity
IHV80_RS20410	COG3119	arylsulfatase activity
IHV80_RS20420	COG0583	DNA-binding transcription factor activity
IHV80_RS20425	COG3119	arylsulfatase activity
IHV80_RS20430	COG0641	radical SAM
IHV80_RS20435	COG0714	Associated with various cellular activities
IHV80_RS20465	COG0583	DNA-binding transcription factor activity
IHV80_RS20470	COG3300	MHYT domain
IHV80_RS20470	COG5001	Diguanylate cyclase
IHV80_RS20495	COG0641	radical SAM
IHV80_RS20505	COG0405	Gamma-glutamyltransferase
IHV80_RS20540	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IHV80_RS20560	COG0745	RESPONSE REGULATOR receiver
IHV80_RS20565	COG1366	Belongs to the anti-sigma-factor antagonist family
IHV80_RS20570	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
IHV80_RS20655	COG5002	protein histidine kinase activity
IHV80_RS20660	COG1881	PFAM PEBP family protein
IHV80_RS20670	COG2807	transmembrane transport
IHV80_RS20675	COG0583	DNA-binding transcription factor activity
IHV80_RS20680	COG3048	D-serine ammonia-lyase activity
IHV80_RS20710	COG1280	lysine exporter protein (LysE YggA)
IHV80_RS20725	COG2165	general secretion pathway protein
IHV80_RS20730	COG0534	Mate efflux family protein
IHV80_RS20755	COG0509	glycine decarboxylation via glycine cleavage system
IHV80_RS20795	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IHV80_RS20800	COG3706	GGDEF domain
IHV80_RS20805	COG2759	Belongs to the formate--tetrahydrofolate ligase family
IHV80_RS20810	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IHV80_RS20825	COG3437	response regulator, receiver
IHV80_RS20825	COG0784	Response regulator, receiver
IHV80_RS20830	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IHV80_RS20840	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IHV80_RS20845	COG0840	transmembrane signaling receptor activity
IHV80_RS20845	COG2203	Gaf domain
IHV80_RS20850	COG0814	amino acid
IHV80_RS20855	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
IHV80_RS20860	COG0513	Belongs to the DEAD box helicase family
IHV80_RS20885	COG2200	EAL domain
IHV80_RS20900	COG3038	cytochrome b561
IHV80_RS20905	COG2353	YceI-like domain
IHV80_RS20910	COG2116	formate transmembrane transporter activity
IHV80_RS20915	COG0583	DNA-binding transcription factor activity
IHV80_RS20925	COG3593	DNA synthesis involved in DNA repair
IHV80_RS20930	COG0737	Belongs to the 5'-nucleotidase family
IHV80_RS20935	COG0861	Integral membrane protein TerC family
IHV80_RS20950	COG0513	Belongs to the DEAD box helicase family
IHV80_RS20970	COG0583	DNA-binding transcription factor activity
IHV80_RS20980	COG2267	carboxylic ester hydrolase activity
IHV80_RS20985	COG2067	long-chain fatty acid transport protein
IHV80_RS20995	COG0501	Belongs to the peptidase M48B family
IHV80_RS21000	COG2050	protein possibly involved in aromatic compounds catabolism
IHV80_RS21010	COG4533	DNA binding
IHV80_RS21040	COG0768	penicillin binding
IHV80_RS21050	COG5001	Diguanylate cyclase
IHV80_RS21050	COG1716	ATPase activity
IHV80_RS21055	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
IHV80_RS21065	COG4181	ATPase activity
IHV80_RS21070	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
IHV80_RS21080	COG1984	allophanate hydrolase subunit 2
IHV80_RS21110	COG4771	TonB-dependent receptor
IHV80_RS21110	COG1629	transport
IHV80_RS21115	COG0583	DNA-binding transcription factor activity
IHV80_RS21120	COG1042	CoA-binding domain protein
IHV80_RS21120	COG0045	succinate-CoA ligase (ADP-forming) activity
IHV80_RS21120	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IHV80_RS21125	COG3266	domain, Protein
IHV80_RS21130	COG1181	Belongs to the D-alanine--D-alanine ligase family
IHV80_RS21145	COG0023	Translation Initiation Factor
IHV80_RS21180	COG3140	Belongs to the UPF0181 family
IHV80_RS21205	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
IHV80_RS21210	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
IHV80_RS21225	COG3706	GGDEF domain
IHV80_RS21235	COG4251	negative regulation of phosphorylation
IHV80_RS21235	COG5001	Diguanylate cyclase
IHV80_RS21235	COG2203	Gaf domain
IHV80_RS21235	COG3706	GGDEF domain
IHV80_RS21245	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
IHV80_RS21250	COG4149	molybdate abc transporter
IHV80_RS21255	COG0725	ABC transporter, periplasmic molybdate-binding protein
IHV80_RS21280	COG0488	(ABC) transporter
IHV80_RS21285	COG4067	protein conserved in archaea
IHV80_RS21285	COG0189	ligase activity
IHV80_RS21300	COG0534	Mate efflux family protein
IHV80_RS21305	COG0602	queuosine metabolic process
IHV80_RS21310	COG1328	CTP reductase activity
IHV80_RS21320	COG2391	methyltransferase activity
IHV80_RS21340	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IHV80_RS21345	COG3118	belongs to the thioredoxin family
IHV80_RS21355	COG0318	PFAM AMP-dependent synthetase and ligase
IHV80_RS21390	COG0534	Mate efflux family protein
IHV80_RS21415	COG1321	iron dependent repressor
IHV80_RS21415	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IHV80_RS21420	COG1121	(ABC) transporter
IHV80_RS21425	COG0803	Belongs to the bacterial solute-binding protein 9 family
IHV80_RS21470	COG0848	biopolymer transport protein
IHV80_RS21475	COG0811	peptide transport
IHV80_RS21480	COG0811	peptide transport
IHV80_RS21490	COG4774	siderophore transport
IHV80_RS21495	COG1301	dicarboxylic acid transport
IHV80_RS21500	COG2205	protein histidine kinase activity
IHV80_RS21505	COG0745	RESPONSE REGULATOR receiver
IHV80_RS21520	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IHV80_RS21520	COG1648	precorrin-2 dehydrogenase activity
IHV80_RS21525	COG2116	formate transmembrane transporter activity
IHV80_RS21535	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IHV80_RS21550	COG0243	molybdopterin cofactor binding
IHV80_RS21560	COG1858	cytochrome C peroxidase
IHV80_RS21565	COG1858	cytochrome C peroxidase
IHV80_RS21630	COG2425	protein containing a von Willebrand factor type A (vWA) domain
IHV80_RS21640	COG0494	nUDIX hydrolase
IHV80_RS21645	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
IHV80_RS21665	COG2197	response regulator
IHV80_RS21675	COG3706	GGDEF domain
IHV80_RS21690	COG2205	protein histidine kinase activity
IHV80_RS21690	COG0784	Response regulator, receiver
IHV80_RS21745	COG1522	sequence-specific DNA binding
IHV80_RS21780	COG2815	serine threonine protein kinase
IHV80_RS21780	COG0515	serine threonine protein kinase
IHV80_RS21805	COG3501	Rhs element vgr protein
IHV80_RS21845	COG0739	heme binding
IHV80_RS21850	COG0582	viral genome integration into host DNA
IHV80_RS21905	COG1012	belongs to the aldehyde dehydrogenase family
IHV80_RS21945	COG3344	reverse transcriptase
IHV80_RS21955	COG1028	Short-chain dehydrogenase reductase Sdr
IHV80_RS21965	COG1902	pentaerythritol trinitrate reductase activity
IHV80_RS21980	COG2003	Belongs to the UPF0758 family
IHV80_RS22010	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IHV80_RS22040	COG2003	Belongs to the UPF0758 family
IHV80_RS22075	COG2199	diguanylate cyclase activity
IHV80_RS22075	COG2203	Gaf domain
IHV80_RS22110	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IHV80_RS22115	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IHV80_RS22120	COG2067	long-chain fatty acid transport protein
IHV80_RS22125	COG2267	carboxylic ester hydrolase activity
IHV80_RS22140	COG3069	C4-dicarboxylate transmembrane transporter activity
IHV80_RS22145	COG2197	response regulator
IHV80_RS22150	COG3850	Histidine kinase
IHV80_RS22155	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IHV80_RS22155	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
IHV80_RS22165	COG0243	molybdopterin cofactor binding
IHV80_RS22175	COG3005	denitrification pathway
IHV80_RS22195	COG0183	Belongs to the thiolase family
IHV80_RS22240	COG0745	RESPONSE REGULATOR receiver
IHV80_RS22270	COG0513	Belongs to the DEAD box helicase family
IHV80_RS22275	COG0523	cobalamin synthesis protein
IHV80_RS22280	COG0038	chloride channel
IHV80_RS22290	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IHV80_RS22290	COG1017	nitric oxide dioxygenase activity
IHV80_RS22295	COG3604	Transcriptional regulator
IHV80_RS22315	COG0545	Peptidyl-prolyl cis-trans isomerase
IHV80_RS22320	COG1309	transcriptional regulator
IHV80_RS22325	COG2130	NADP-dependent
IHV80_RS22335	COG0564	pseudouridine synthase activity
IHV80_RS22345	COG0583	DNA-binding transcription factor activity
IHV80_RS22355	COG1686	Belongs to the peptidase S11 family
IHV80_RS22370	COG3706	GGDEF domain
IHV80_RS22380	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IHV80_RS22390	COG3059	membrane
IHV80_RS22410	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IHV80_RS22435	COG2207	Transcriptional regulator
IHV80_RS22440	COG1979	alcohol dehydrogenase
IHV80_RS22445	COG1126	abc transporter atp-binding protein
IHV80_RS22450	COG0765	amino acid transport
IHV80_RS22460	COG0765	amino acid transport
IHV80_RS22470	COG1629	transport
IHV80_RS22470	COG4771	TonB-dependent receptor
IHV80_RS22475	COG4977	sequence-specific DNA binding
IHV80_RS22485	COG1280	lysine exporter protein (LysE YggA)
IHV80_RS22525	COG2824	Alkylphosphonate utilization operon protein PhnA
IHV80_RS22555	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IHV80_RS22560	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IHV80_RS22580	COG1902	pentaerythritol trinitrate reductase activity
IHV80_RS22590	COG3710	Transcriptional regulator
IHV80_RS22605	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IHV80_RS22610	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IHV80_RS22620	COG2985	domain, Protein
IHV80_RS22640	COG1024	Enoyl-CoA hydratase
IHV80_RS22645	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IHV80_RS22670	COG1120	ATPase activity
IHV80_RS22680	COG2133	pyrroloquinoline quinone binding
IHV80_RS22685	COG1278	Cold shock
IHV80_RS22780	COG4228	DNA circulation
IHV80_RS22815	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
IHV80_RS22840	COG4695	Portal protein
IHV80_RS22880	COG4386	tail sheath protein
IHV80_RS22935	COG0302	gtp cyclohydrolase
IHV80_RS22960	COG2897	thiosulfate sulfurtransferase activity
IHV80_RS22965	COG5001	Diguanylate cyclase
IHV80_RS22965	COG2203	Gaf domain
IHV80_RS22965	COG4251	negative regulation of phosphorylation
IHV80_RS22965	COG3706	GGDEF domain
IHV80_RS23020	COG4964	Belongs to the GSP D family
IHV80_RS23070	COG0840	transmembrane signaling receptor activity
IHV80_RS23075	COG1522	sequence-specific DNA binding
IHV80_RS23095	COG2814	Major facilitator Superfamily
IHV80_RS23100	COG0583	DNA-binding transcription factor activity
IHV80_RS23105	COG2205	protein histidine kinase activity
IHV80_RS23105	COG3437	response regulator, receiver
IHV80_RS23105	COG3850	Histidine kinase
IHV80_RS23105	COG4999	Histidine kinase
IHV80_RS23110	COG3437	response regulator, receiver
IHV80_RS23115	COG4604	ABC transporter, ATP-binding protein
IHV80_RS23120	COG4605	iron ion homeostasis
IHV80_RS23125	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IHV80_RS23130	COG4607	ABC-type enterochelin transport system periplasmic component
IHV80_RS23155	COG0628	permease
IHV80_RS23165	COG1566	PFAM secretion protein HlyD family protein
IHV80_RS23175	COG3706	GGDEF domain
IHV80_RS23205	COG0583	DNA-binding transcription factor activity
IHV80_RS23215	COG0352	thiamine-phosphate diphosphorylase activity
IHV80_RS23220	COG0840	transmembrane signaling receptor activity
IHV80_RS23225	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
IHV80_RS23230	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IHV80_RS23235	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IHV80_RS23240	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IHV80_RS23245	COG1116	anion transmembrane transporter activity
IHV80_RS23250	COG0351	phosphomethylpyrimidine kinase
IHV80_RS23255	COG0697	spore germination
IHV80_RS23290	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
IHV80_RS23300	COG0516	GMP reductase activity
IHV80_RS23310	COG4999	Histidine kinase
IHV80_RS23310	COG3437	response regulator, receiver
IHV80_RS23310	COG2205	protein histidine kinase activity
IHV80_RS23310	COG3850	Histidine kinase
IHV80_RS23325	COG0534	Mate efflux family protein
IHV80_RS23330	COG0583	DNA-binding transcription factor activity
IHV80_RS23340	COG0366	Alpha amylase catalytic
IHV80_RS23360	COG0604	alcohol dehydrogenase
IHV80_RS23415	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IHV80_RS23420	COG0513	Belongs to the DEAD box helicase family
IHV80_RS23425	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
IHV80_RS23440	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IHV80_RS23475	COG2195	Cleaves the N-terminal amino acid of tripeptides
IHV80_RS23485	COG0667	Aldo Keto reductase
IHV80_RS23490	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IHV80_RS23495	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
IHV80_RS23500	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
IHV80_RS23515	COG0778	Nitroreductase
IHV80_RS23520	COG0513	Belongs to the DEAD box helicase family
IHV80_RS23530	COG2176	DNA-directed DNA polymerase activity
IHV80_RS23545	COG0513	Belongs to the DEAD box helicase family
IHV80_RS23550	COG4989	oxidoreductase activity
IHV80_RS23570	COG1538	Outer membrane efflux protein
IHV80_RS23575	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IHV80_RS23610	COG2197	response regulator
IHV80_RS23620	COG0668	transmembrane transport
IHV80_RS23630	COG4232	protein-disulfide reductase activity
IHV80_RS23635	COG3118	belongs to the thioredoxin family
IHV80_RS23655	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
IHV80_RS23660	COG0697	spore germination
IHV80_RS23675	COG2814	Major facilitator Superfamily
IHV80_RS23680	COG0583	DNA-binding transcription factor activity
IHV80_RS23685	COG5001	Diguanylate cyclase
IHV80_RS23690	COG0739	heme binding
IHV80_RS23715	COG3314	Sporulation integral membrane protein YlbJ
IHV80_RS23725	COG0366	Alpha amylase catalytic
IHV80_RS23730	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IHV80_RS23735	COG0835	chemotaxis
IHV80_RS23735	COG0784	Response regulator, receiver
IHV80_RS23740	COG2096	Adenosyltransferase
IHV80_RS23745	COG0748	coenzyme F420 binding
IHV80_RS23750	COG3721	Heme iron utilization protein
IHV80_RS23760	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
IHV80_RS23765	COG0811	peptide transport
IHV80_RS23770	COG0848	biopolymer transport protein
IHV80_RS23780	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IHV80_RS23785	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
IHV80_RS23830	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
IHV80_RS23835	COG0633	Ferredoxin
IHV80_RS23835	COG3217	Mosc domain protein beta barrel domain protein
IHV80_RS23845	COG0418	dihydroorotase activity
IHV80_RS23850	COG2354	Protein conserved in bacteria
IHV80_RS23860	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IHV80_RS23875	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
IHV80_RS23875	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
IHV80_RS23880	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
IHV80_RS23885	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IHV80_RS23890	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IHV80_RS23920	COG0730	response to heat
IHV80_RS23930	COG1414	Transcriptional regulator
IHV80_RS23935	COG1012	belongs to the aldehyde dehydrogenase family
IHV80_RS23965	COG4934	collagen metabolic process
IHV80_RS24010	COG1566	PFAM secretion protein HlyD family protein
IHV80_RS24025	COG2356	endonuclease I
IHV80_RS24030	COG1136	(ABC) transporter
IHV80_RS24035	COG0577	efflux transmembrane transporter activity
IHV80_RS24075	COG3833	ABC-type maltose transport systems, permease component
IHV80_RS24080	COG1175	transmembrane transport
IHV80_RS24090	COG3842	ATPase activity
IHV80_RS24100	COG0840	transmembrane signaling receptor activity
IHV80_RS24120	COG0714	Associated with various cellular activities
IHV80_RS24135	COG2304	oxidoreductase activity
IHV80_RS24140	COG2304	oxidoreductase activity
IHV80_RS24155	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IHV80_RS24160	COG0581	inorganic phosphate transmembrane transporter activity
IHV80_RS24165	COG0573	inorganic phosphate transmembrane transporter activity
IHV80_RS24175	COG0840	transmembrane signaling receptor activity
IHV80_RS24195	COG4771	TonB-dependent receptor
IHV80_RS24210	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
IHV80_RS24215	COG3240	lipase activity
IHV80_RS24220	COG0513	Belongs to the DEAD box helicase family
IHV80_RS24230	COG1376	ErfK ybiS ycfS ynhG family protein
IHV80_RS24230	COG1388	LysM domain
IHV80_RS24235	COG0813	purine-nucleoside phosphorylase activity
IHV80_RS24265	COG1566	PFAM secretion protein HlyD family protein
IHV80_RS24280	COG2814	Major facilitator Superfamily
IHV80_RS24285	COG2814	Major facilitator Superfamily
IHV80_RS24290	COG1686	Belongs to the peptidase S11 family
IHV80_RS24295	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IHV80_RS24305	COG0814	amino acid
IHV80_RS24310	COG2211	Major facilitator Superfamily
IHV80_RS24315	COG1397	ADP-ribosylglycohydrolase
IHV80_RS24320	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IHV80_RS24325	COG2223	nitrite transmembrane transporter activity
IHV80_RS24330	COG2188	Transcriptional regulator
IHV80_RS24335	COG0840	transmembrane signaling receptor activity
IHV80_RS24350	COG3226	Transcriptional regulator
IHV80_RS24360	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IHV80_RS24365	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IHV80_RS24375	COG2207	Transcriptional regulator
IHV80_RS24380	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IHV80_RS24380	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IHV80_RS24380	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IHV80_RS24395	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IHV80_RS24400	COG3842	ATPase activity
IHV80_RS24405	COG0546	phosphoglycolate phosphatase activity
IHV80_RS24430	COG0583	DNA-binding transcription factor activity
IHV80_RS24435	COG4166	transmembrane transport
IHV80_RS24460	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
IHV80_RS24465	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
IHV80_RS24490	COG1288	antiporter activity
IHV80_RS24505	COG1012	belongs to the aldehyde dehydrogenase family
IHV80_RS24510	COG3284	Transcriptional regulator
IHV80_RS24515	COG0840	transmembrane signaling receptor activity
IHV80_RS24520	COG0583	DNA-binding transcription factor activity
IHV80_RS24525	COG0625	glutathione transferase activity
IHV80_RS24530	COG3655	Transcriptional regulator
IHV80_RS24540	COG0583	DNA-binding transcription factor activity
IHV80_RS24575	COG1737	Transcriptional regulator
IHV80_RS24580	COG1263	PTS System
IHV80_RS24580	COG2190	(PTS) system
IHV80_RS24580	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IHV80_RS24595	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
IHV80_RS24600	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IHV80_RS24605	COG1418	mRNA catabolic process
IHV80_RS24620	COG2186	Transcriptional regulator
IHV80_RS24630	COG1529	Aldehyde oxidase and xanthine dehydrogenase
IHV80_RS24640	COG0402	S-adenosylhomocysteine deaminase activity
IHV80_RS24665	COG0251	oxidation-reduction process
IHV80_RS24670	COG0583	DNA-binding transcription factor activity
IHV80_RS24695	COG1309	transcriptional regulator
IHV80_RS24705	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
IHV80_RS24710	COG4266	Belongs to the allantoicase family
IHV80_RS24730	COG2252	PERMEase
IHV80_RS24760	COG2721	sulfolactate sulfo-lyase activity
IHV80_RS24770	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IHV80_RS24775	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
IHV80_RS24785	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IHV80_RS24790	COG0800	Aldolase
IHV80_RS24795	COG1802	Transcriptional regulator
IHV80_RS24800	COG1063	alcohol dehydrogenase
IHV80_RS24815	COG0745	RESPONSE REGULATOR receiver
IHV80_RS24820	COG2205	protein histidine kinase activity
IHV80_RS24820	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IHV80_RS24835	COG2084	Dehydrogenase
IHV80_RS24840	COG3622	Belongs to the hyi family
IHV80_RS24845	COG3960	tartronate-semialdehyde synthase activity
IHV80_RS24850	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
IHV80_RS24860	COG2259	Doxx family
IHV80_RS24865	COG0583	DNA-binding transcription factor activity
IHV80_RS24875	COG1846	Transcriptional regulator
IHV80_RS24885	COG0583	DNA-binding transcription factor activity
IHV80_RS24965	COG4964	Belongs to the GSP D family
IHV80_RS25055	COG1067	ATP-dependent peptidase activity
IHV80_RS25065	COG4172	Belongs to the ABC transporter superfamily
IHV80_RS25070	COG1609	Transcriptional regulator
IHV80_RS25080	COG2017	converts alpha-aldose to the beta-anomer
IHV80_RS25085	COG3459	Glycosyltransferase 36 associated
IHV80_RS25090	COG3842	ATPase activity
IHV80_RS25095	COG2723	6-phospho-beta-galactosidase activity
IHV80_RS25100	COG0395	ABC-type sugar transport system, permease component
IHV80_RS25115	COG1609	Transcriptional regulator