locus-tag	class	description
FIV04_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FIV04_RS00010	COG0592	DNA-directed DNA polymerase activity
FIV04_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FIV04_RS00020	COG0187	DNA topoisomerase II activity
FIV04_RS00025	COG0071	Belongs to the small heat shock protein (HSP20) family
FIV04_RS00030	COG3977	Valine--pyruvate aminotransferase
FIV04_RS00035	COG0366	Alpha amylase catalytic
FIV04_RS00040	COG0751	glycine-tRNA ligase activity
FIV04_RS00045	COG0752	glycyl-tRNA synthetase alpha subunit
FIV04_RS00050	COG2119	membrane
FIV04_RS00060	COG0425	Belongs to the sulfur carrier protein TusA family
FIV04_RS00075	COG0604	alcohol dehydrogenase
FIV04_RS00080	COG0183	Belongs to the thiolase family
FIV04_RS00085	COG1250	3-hydroxyacyl-CoA dehydrogenase
FIV04_RS00085	COG1024	Enoyl-CoA hydratase
FIV04_RS00090	COG1739	Uncharacterized protein family UPF0029
FIV04_RS00095	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FIV04_RS00140	COG0583	DNA-binding transcription factor activity
FIV04_RS00145	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FIV04_RS00150	COG2960	long-chain fatty acid transporting porin activity
FIV04_RS00155	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FIV04_RS00160	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FIV04_RS00165	COG1309	transcriptional regulator
FIV04_RS00215	COG0601	transmembrane transport
FIV04_RS00220	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FIV04_RS00275	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FIV04_RS00285	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FIV04_RS00290	COG0339	signal peptide processing
FIV04_RS00295	COG1522	sequence-specific DNA binding
FIV04_RS00300	COG5002	protein histidine kinase activity
FIV04_RS00300	COG5001	Diguanylate cyclase
FIV04_RS00305	COG0742	ribosomal rna small subunit methyltransferase
FIV04_RS00320	COG0589	response to stress
FIV04_RS00325	COG1528	Iron-storage protein
FIV04_RS00335	COG2081	HI0933 family
FIV04_RS00345	COG1322	Protein conserved in bacteria
FIV04_RS00350	COG2226	methyltransferase
FIV04_RS00355	COG3165	ubiquinone biosynthetic process from chorismate
FIV04_RS00360	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FIV04_RS00365	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FIV04_RS00370	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FIV04_RS00375	COG0805	protein transport
FIV04_RS00380	COG0084	hydrolase, TatD family'
FIV04_RS00395	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FIV04_RS00395	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FIV04_RS00420	COG3078	GTPase activator activity
FIV04_RS00440	COG2204	response regulator
FIV04_RS00445	COG3852	Histidine kinase
FIV04_RS00455	COG0174	glutamine synthetase
FIV04_RS00460	COG1217	gtp-binding protein TYPA
FIV04_RS00475	COG1295	ribonuclease BN
FIV04_RS00480	COG1490	D-aminoacyl-tRNA deacylase activity
FIV04_RS00485	COG0456	acetyltransferase
FIV04_RS00495	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FIV04_RS00505	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FIV04_RS00510	COG3031	protein transport across the cell outer membrane
FIV04_RS00520	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FIV04_RS00525	COG1459	type II secretion system
FIV04_RS00530	COG2165	general secretion pathway protein
FIV04_RS00535	COG2165	general secretion pathway protein
FIV04_RS00540	COG2165	general secretion pathway protein
FIV04_RS00545	COG4795	General secretion pathway protein
FIV04_RS00550	COG3156	type II secretion system protein K
FIV04_RS00555	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
FIV04_RS00560	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
FIV04_RS00570	COG1218	3'(2'),5'-bisphosphate nucleotidase
FIV04_RS00575	COG0494	nUDIX hydrolase
FIV04_RS00580	COG0316	Belongs to the HesB IscA family
FIV04_RS00580	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FIV04_RS00585	COG1040	competence protein
FIV04_RS00590	COG0596	Alpha beta hydrolase
FIV04_RS00600	COG2183	response to ionizing radiation
FIV04_RS00605	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FIV04_RS00620	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FIV04_RS00625	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FIV04_RS00630	COG1758	RNA polymerase activity
FIV04_RS00635	COG0194	GDP metabolic process
FIV04_RS00640	COG2252	PERMEase
FIV04_RS00665	COG1561	YicC-like family, N-terminal region
FIV04_RS00670	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FIV04_RS00675	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FIV04_RS00680	COG1560	Kdo2-lipid A biosynthetic process
FIV04_RS00685	COG1309	transcriptional regulator
FIV04_RS00705	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FIV04_RS00710	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FIV04_RS00725	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FIV04_RS00735	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FIV04_RS00740	COG0859	PFAM glycosyl transferase family 9
FIV04_RS00745	COG0463	Glycosyl transferase, family 2
FIV04_RS00750	COG0859	PFAM glycosyl transferase family 9
FIV04_RS00755	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FIV04_RS00760	COG3642	lipopolysaccharide core region biosynthetic process
FIV04_RS00765	COG3083	sulfuric ester hydrolase activity
FIV04_RS00785	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FIV04_RS00790	COG0673	inositol 2-dehydrogenase activity
FIV04_RS00800	COG0463	Glycosyl transferase, family 2
FIV04_RS00810	COG0297	glycogen (starch) synthase activity
FIV04_RS00810	COG0438	transferase activity, transferring glycosyl groups
FIV04_RS00820	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FIV04_RS00825	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FIV04_RS00830	COG2089	acid synthase
FIV04_RS00850	COG1083	cytidylyl-transferase
FIV04_RS00855	COG1028	Short-chain dehydrogenase reductase Sdr
FIV04_RS00870	COG1519	Transferase
FIV04_RS00875	COG0859	PFAM glycosyl transferase family 9
FIV04_RS00880	COG1560	Kdo2-lipid A biosynthetic process
FIV04_RS00895	COG4942	peptidase
FIV04_RS00900	COG1045	serine acetyltransferase
FIV04_RS00910	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FIV04_RS00915	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FIV04_RS00935	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FIV04_RS00955	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FIV04_RS00960	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FIV04_RS00965	COG2089	acid synthase
FIV04_RS00970	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FIV04_RS00975	COG1083	cytidylyl-transferase
FIV04_RS00995	COG0110	maltose O-acetyltransferase activity
FIV04_RS01025	COG0673	inositol 2-dehydrogenase activity
FIV04_RS01045	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FIV04_RS01060	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FIV04_RS01065	COG0534	Mate efflux family protein
FIV04_RS01070	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FIV04_RS01075	COG0459	protein refolding
FIV04_RS01090	COG2199	diguanylate cyclase activity
FIV04_RS01090	COG2203	Gaf domain
FIV04_RS01095	COG1285	pathogenesis
FIV04_RS01100	COG4968	Prepilin-type N-terminal cleavage methylation domain
FIV04_RS01105	COG1509	lysine 2,3-aminomutase activity
FIV04_RS01110	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FIV04_RS01130	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
FIV04_RS01135	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FIV04_RS01140	COG1053	succinate dehydrogenase
FIV04_RS01145	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
FIV04_RS01155	COG0490	domain, Protein
FIV04_RS01155	COG0471	metal ion transport
FIV04_RS01160	COG0688	phosphatidylethanolamine metabolic process
FIV04_RS01165	COG1162	GTPase activity
FIV04_RS01245	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FIV04_RS01250	COG0802	atpase or kinase
FIV04_RS01255	COG0860	N-Acetylmuramoyl-L-alanine amidase
FIV04_RS01260	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FIV04_RS01265	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FIV04_RS01270	COG1923	regulation of RNA biosynthetic process
FIV04_RS01275	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FIV04_RS01280	COG0330	HflC and HflK could
FIV04_RS01285	COG0330	HflC and HflK could
FIV04_RS01290	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
FIV04_RS01295	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FIV04_RS01305	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
FIV04_RS01310	COG0402	S-adenosylhomocysteine deaminase activity
FIV04_RS01315	COG0557	exoribonuclease II activity
FIV04_RS01320	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FIV04_RS01335	COG0359	binds to the 23S rRNA
FIV04_RS01350	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FIV04_RS01360	COG0432	Pfam Uncharacterised protein family UPF0047
FIV04_RS01365	COG0166	Belongs to the GPI family
FIV04_RS01375	COG0735	belongs to the Fur family
FIV04_RS01400	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FIV04_RS01405	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FIV04_RS01410	COG0175	sulfate reduction
FIV04_RS01500	COG0646	methionine synthase
FIV04_RS01500	COG1410	methionine synthase
FIV04_RS01505	COG0527	aspartate kinase activity
FIV04_RS01510	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FIV04_RS01520	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FIV04_RS01530	COG2197	response regulator
FIV04_RS01535	COG0629	single-stranded DNA binding
FIV04_RS01540	COG2200	EAL domain
FIV04_RS01540	COG2199	diguanylate cyclase activity
FIV04_RS01565	COG3409	Peptidoglycan-binding domain 1 protein
FIV04_RS01565	COG3267	Type II secretory pathway component ExeA
FIV04_RS01575	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FIV04_RS01580	COG1459	type II secretion system
FIV04_RS01590	COG2165	general secretion pathway protein
FIV04_RS01595	COG2165	general secretion pathway protein
FIV04_RS01625	COG1077	Cell shape determining protein MreB Mrl
FIV04_RS01630	COG1792	Involved in formation and maintenance of cell shape
FIV04_RS01635	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FIV04_RS01640	COG0424	maF-like protein
FIV04_RS01655	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FIV04_RS01660	COG0312	modulator of DNA gyrase
FIV04_RS01665	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FIV04_RS01670	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FIV04_RS01680	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FIV04_RS01685	COG0589	response to stress
FIV04_RS01695	COG2358	TRAP transporter, solute receptor (TAXI family
FIV04_RS01700	COG1438	arginine binding
FIV04_RS01705	COG0039	L-malate dehydrogenase activity
FIV04_RS01715	COG0142	geranyltranstransferase activity
FIV04_RS01725	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FIV04_RS01730	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FIV04_RS01735	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FIV04_RS01740	COG2966	Psort location CytoplasmicMembrane, score
FIV04_RS01745	COG3610	response to peptide
FIV04_RS01760	COG2967	ApaG domain
FIV04_RS01765	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FIV04_RS01770	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FIV04_RS01775	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FIV04_RS01780	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FIV04_RS01785	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FIV04_RS01810	COG0473	3-isopropylmalate dehydrogenase activity
FIV04_RS01815	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FIV04_RS01850	COG1022	Amp-dependent synthetase and ligase
FIV04_RS01855	COG0028	Belongs to the TPP enzyme family
FIV04_RS01875	COG1802	Transcriptional regulator
FIV04_RS01880	COG0469	pyruvate kinase activity
FIV04_RS01885	COG1349	DNA-binding transcription factor activity
FIV04_RS01890	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FIV04_RS01895	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FIV04_RS01900	COG2873	o-acetylhomoserine
FIV04_RS01920	COG1610	YqeY-like protein
FIV04_RS01925	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FIV04_RS01930	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FIV04_RS01935	COG0596	Alpha beta hydrolase
FIV04_RS01940	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FIV04_RS01945	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FIV04_RS01955	COG1968	undecaprenyl-diphosphatase activity
FIV04_RS01960	COG0617	tRNA 3'-terminal CCA addition
FIV04_RS01965	COG3267	Type II secretory pathway component ExeA
FIV04_RS01965	COG3409	Peptidoglycan-binding domain 1 protein
FIV04_RS01975	COG4991	sh3 domain protein
FIV04_RS01980	COG0306	phosphate transporter
FIV04_RS01985	COG1392	Phosphate transport regulator
FIV04_RS01990	COG3025	triphosphatase activity
FIV04_RS01995	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FIV04_RS02005	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FIV04_RS02010	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FIV04_RS02010	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FIV04_RS02015	COG1538	Outer membrane efflux protein
FIV04_RS02020	COG0494	nUDIX hydrolase
FIV04_RS02025	COG3151	Protein conserved in bacteria
FIV04_RS02035	COG3150	esterase
FIV04_RS02050	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FIV04_RS02055	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FIV04_RS02060	COG3105	Protein conserved in bacteria
FIV04_RS02065	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FIV04_RS02080	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FIV04_RS02085	COG0723	plastoquinol--plastocyanin reductase activity
FIV04_RS02090	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FIV04_RS02095	COG2857	Cytochrome c1
FIV04_RS02100	COG0625	glutathione transferase activity
FIV04_RS02105	COG2969	positive regulation of protein catabolic process
FIV04_RS02110	COG2823	Periplasmic or secreted lipoprotein
FIV04_RS02115	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FIV04_RS02120	COG0792	nuclease activity
FIV04_RS02130	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FIV04_RS02140	COG0275	rRNA processing
FIV04_RS02145	COG3116	cell division
FIV04_RS02150	COG0768	penicillin binding
FIV04_RS02155	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FIV04_RS02160	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FIV04_RS02165	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FIV04_RS02170	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FIV04_RS02175	COG0772	Belongs to the SEDS family
FIV04_RS02180	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FIV04_RS02185	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FIV04_RS02195	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FIV04_RS02200	COG0849	cell division
FIV04_RS02205	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FIV04_RS02210	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
FIV04_RS02215	COG0653	protein targeting
FIV04_RS02220	COG0494	nUDIX hydrolase
FIV04_RS02225	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FIV04_RS02230	COG0505	Belongs to the CarA family
FIV04_RS02235	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FIV04_RS02240	COG0730	response to heat
FIV04_RS02245	COG0583	DNA-binding transcription factor activity
FIV04_RS02260	COG2860	membrane
FIV04_RS02265	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FIV04_RS02275	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FIV04_RS02285	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FIV04_RS02290	COG0067	glutamate synthase
FIV04_RS02290	COG0069	glutamate synthase activity
FIV04_RS02290	COG0070	glutamate synthase
FIV04_RS02300	COG0067	glutamate synthase
FIV04_RS02300	COG0069	glutamate synthase activity
FIV04_RS02300	COG0070	glutamate synthase
FIV04_RS02305	COG1242	4 iron, 4 sulfur cluster binding
FIV04_RS02310	COG2203	Gaf domain
FIV04_RS02310	COG5001	Diguanylate cyclase
FIV04_RS02310	COG4251	negative regulation of phosphorylation
FIV04_RS02310	COG3706	GGDEF domain
FIV04_RS02315	COG2198	Histidine kinase
FIV04_RS02315	COG5002	protein histidine kinase activity
FIV04_RS02315	COG0784	Response regulator, receiver
FIV04_RS02325	COG0745	RESPONSE REGULATOR receiver
FIV04_RS02330	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FIV04_RS02345	COG0083	homoserine kinase activity
FIV04_RS02350	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FIV04_RS02355	COG0431	NADPH-dependent FMN reductase
FIV04_RS02360	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
FIV04_RS02365	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
FIV04_RS02385	COG1115	amino acid carrier protein
FIV04_RS02390	COG3022	response to hydroperoxide
FIV04_RS02395	COG0513	Belongs to the DEAD box helicase family
FIV04_RS02400	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FIV04_RS02410	COG0716	FMN binding
FIV04_RS02415	COG4974	Belongs to the 'phage' integrase family
FIV04_RS02420	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FIV04_RS02425	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FIV04_RS02435	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FIV04_RS02465	COG0494	nUDIX hydrolase
FIV04_RS02475	COG0730	response to heat
FIV04_RS02480	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FIV04_RS02485	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FIV04_RS02490	COG1283	sodium-dependent phosphate transmembrane transporter activity
FIV04_RS02495	COG0583	DNA-binding transcription factor activity
FIV04_RS02500	COG0640	Transcriptional regulator
FIV04_RS02505	COG0268	Binds directly to 16S ribosomal RNA
FIV04_RS02510	COG0728	peptidoglycan biosynthetic process
FIV04_RS02515	COG0196	riboflavin kinase activity
FIV04_RS02520	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FIV04_RS02530	COG1047	Peptidyl-prolyl cis-trans
FIV04_RS02535	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FIV04_RS02540	COG3279	Response regulator of the LytR AlgR family
FIV04_RS02545	COG3275	phosphorelay sensor kinase activity
FIV04_RS02550	COG1966	Carbon starvation protein
FIV04_RS02560	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FIV04_RS02565	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FIV04_RS02575	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FIV04_RS02580	COG0287	Prephenate dehydrogenase
FIV04_RS02580	COG1605	Chorismate mutase
FIV04_RS02585	COG0739	heme binding
FIV04_RS02595	COG0488	(ABC) transporter
FIV04_RS02605	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
FIV04_RS02610	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
FIV04_RS02615	COG5001	Diguanylate cyclase
FIV04_RS02620	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FIV04_RS02625	COG1605	Chorismate mutase
FIV04_RS02625	COG0077	Prephenate dehydratase
FIV04_RS02630	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FIV04_RS02635	COG0741	lytic transglycosylase activity
FIV04_RS02640	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FIV04_RS02645	COG0564	pseudouridine synthase activity
FIV04_RS02695	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
FIV04_RS02705	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FIV04_RS02710	COG0826	peptidase U32
FIV04_RS02715	COG2974	May be involved in recombination
FIV04_RS02720	COG0745	RESPONSE REGULATOR receiver
FIV04_RS02725	COG5002	protein histidine kinase activity
FIV04_RS02735	COG0248	Ppx GppA phosphatase
FIV04_RS02740	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FIV04_RS02745	COG0573	inorganic phosphate transmembrane transporter activity
FIV04_RS02750	COG0581	inorganic phosphate transmembrane transporter activity
FIV04_RS02755	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FIV04_RS02760	COG0704	Plays a role in the regulation of phosphate uptake
FIV04_RS02780	COG3142	Participates in the control of copper homeostasis
FIV04_RS02785	COG0450	alkyl hydroperoxide reductase
FIV04_RS02790	COG0583	DNA-binding transcription factor activity
FIV04_RS02795	COG0517	IMP dehydrogenase activity
FIV04_RS02800	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FIV04_RS02805	COG0343	queuine tRNA-ribosyltransferase activity
FIV04_RS02810	COG1862	Preprotein translocase
FIV04_RS02815	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FIV04_RS02820	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FIV04_RS02835	COG0483	inositol monophosphate 1-phosphatase activity
FIV04_RS02840	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
FIV04_RS02845	COG1959	2 iron, 2 sulfur cluster binding
FIV04_RS02850	COG1104	cysteine desulfurase activity
FIV04_RS02855	COG0822	iron-sulfur transferase activity
FIV04_RS02870	COG0443	Heat shock 70 kDa protein
FIV04_RS02880	COG2975	iron-sulfur cluster assembly
FIV04_RS02885	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FIV04_RS02890	COG0105	UTP biosynthetic process
FIV04_RS02895	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FIV04_RS02900	COG1426	Protein conserved in bacteria
FIV04_RS02905	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FIV04_RS02910	COG0124	histidyl-tRNA synthetase
FIV04_RS02915	COG2976	Protein conserved in bacteria
FIV04_RS02920	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FIV04_RS02925	COG1160	GTP binding
FIV04_RS02935	COG3706	GGDEF domain
FIV04_RS02975	COG0831	urea catabolic process
FIV04_RS02980	COG0832	Belongs to the urease beta subunit family
FIV04_RS02985	COG0804	urea catabolic process
FIV04_RS02990	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
FIV04_RS03000	COG0830	nickel cation binding
FIV04_RS03005	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FIV04_RS03010	COG1570	exodeoxyribonuclease VII activity
FIV04_RS03015	COG0516	GMP reductase activity
FIV04_RS03015	COG0517	IMP dehydrogenase activity
FIV04_RS03020	COG0519	Catalyzes the synthesis of GMP from XMP
FIV04_RS03020	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FIV04_RS03030	COG1584	GPR1 FUN34 yaaH family protein
FIV04_RS03035	COG1115	amino acid carrier protein
FIV04_RS03040	COG2213	PTS system mannitol-specific
FIV04_RS03040	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FIV04_RS03045	COG3722	fumarate hydratase activity
FIV04_RS03050	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FIV04_RS03055	COG0204	Acyl-transferase
FIV04_RS03150	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FIV04_RS03160	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FIV04_RS03165	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FIV04_RS03175	COG2205	protein histidine kinase activity
FIV04_RS03190	COG1858	cytochrome C peroxidase
FIV04_RS03205	COG4067	protein conserved in archaea
FIV04_RS03205	COG0189	ligase activity
FIV04_RS03220	COG2867	negative regulation of translational initiation
FIV04_RS03225	COG2914	Belongs to the UPF0125 (RnfH) family
FIV04_RS03230	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FIV04_RS03235	COG0497	DNA recombination
FIV04_RS03245	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FIV04_RS03250	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FIV04_RS03255	COG1301	dicarboxylic acid transport
FIV04_RS03265	COG0443	Heat shock 70 kDa protein
FIV04_RS03270	COG0484	heat shock protein binding
FIV04_RS03300	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
FIV04_RS03305	COG1253	flavin adenine dinucleotide binding
FIV04_RS03315	COG1764	response to oxidative stress
FIV04_RS03320	COG1846	Transcriptional regulator
FIV04_RS03330	COG0047	phosphoribosylformylglycinamidine synthase activity
FIV04_RS03330	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FIV04_RS03340	COG2171	N-acyltransferase activity
FIV04_RS03345	COG2095	MarC family integral membrane protein
FIV04_RS03360	COG3141	response to X-ray
FIV04_RS03375	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FIV04_RS03380	COG1074	ATP-dependent DNA helicase activity
FIV04_RS03385	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FIV04_RS03395	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FIV04_RS03395	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FIV04_RS03405	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FIV04_RS03410	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FIV04_RS03415	COG2166	iron-sulfur cluster assembly
FIV04_RS03420	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FIV04_RS03425	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FIV04_RS03435	COG2211	Major facilitator Superfamily
FIV04_RS03440	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FIV04_RS03450	COG2813	Specifically methylates the guanine in position
FIV04_RS03455	COG0271	Belongs to the BolA IbaG family
FIV04_RS03460	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FIV04_RS03465	COG1805	sodium ion transport
FIV04_RS03475	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FIV04_RS03480	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FIV04_RS03490	COG1477	protein flavinylation
FIV04_RS03495	COG2991	Protein conserved in bacteria
FIV04_RS03505	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FIV04_RS03515	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FIV04_RS03525	COG0733	neurotransmitter:sodium symporter activity
FIV04_RS03530	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FIV04_RS03535	COG0321	lipoyl(octanoyl) transferase activity
FIV04_RS03545	COG1686	Belongs to the peptidase S11 family
FIV04_RS03550	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FIV04_RS03555	COG0772	Belongs to the SEDS family
FIV04_RS03560	COG0768	penicillin binding
FIV04_RS03570	COG0799	negative regulation of ribosome biogenesis
FIV04_RS03575	COG1466	dna polymerase III delta subunit
FIV04_RS03580	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
FIV04_RS03585	COG0495	leucyl-tRNA aminoacylation
FIV04_RS03590	COG2888	peptidyl-tyrosine sulfation
FIV04_RS03595	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FIV04_RS03600	COG4535	Mg2 and Co2 transporter CorC
FIV04_RS03605	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FIV04_RS03610	COG1702	phosphate starvation-inducible protein PhoH
FIV04_RS03615	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FIV04_RS03620	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FIV04_RS03625	COG2706	6-phosphogluconolactonase activity
FIV04_RS03740	COG0193	aminoacyl-tRNA hydrolase activity
FIV04_RS03745	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FIV04_RS03750	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FIV04_RS03755	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
FIV04_RS03760	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FIV04_RS03765	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FIV04_RS03770	COG2890	protein-(glutamine-N5) methyltransferase activity
FIV04_RS03780	COG2912	Transglutaminase-like superfamily
FIV04_RS03785	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FIV04_RS03795	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FIV04_RS03800	COG1187	pseudouridine synthase activity
FIV04_RS03805	COG2840	Smr protein MutS2
FIV04_RS03845	COG2608	mercury ion transmembrane transporter activity
FIV04_RS03845	COG2217	Heavy metal translocating P-type atpase
FIV04_RS03865	COG1028	Short-chain dehydrogenase reductase Sdr
FIV04_RS03875	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FIV04_RS03900	COG2986	histidine ammonia-lyase
FIV04_RS03905	COG1216	Glycosyl transferase, family 2
FIV04_RS03925	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FIV04_RS03930	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FIV04_RS03990	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
FIV04_RS03995	COG0835	chemotaxis
FIV04_RS03995	COG0784	Response regulator, receiver
FIV04_RS04000	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FIV04_RS04005	COG1815	bacterial-type flagellum-dependent cell motility
FIV04_RS04025	COG4787	bacterial-type flagellum-dependent cell motility
FIV04_RS04035	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FIV04_RS04040	COG1706	bacterial-type flagellum-dependent cell motility
FIV04_RS04045	COG3951	Flagellar rod assembly protein muramidase FlgJ
FIV04_RS04045	COG1705	Flagellar rod assembly protein muramidase FlgJ
FIV04_RS04060	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FIV04_RS04070	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FIV04_RS04075	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FIV04_RS04080	COG1334	flagellar protein FlaG
FIV04_RS04085	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FIV04_RS04095	COG1516	flagellar protein fliS
FIV04_RS04115	COG1677	Flagellar hook-basal body complex protein FliE
FIV04_RS04125	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FIV04_RS04175	COG1987	bacterial-type flagellum assembly
FIV04_RS04180	COG1684	flagellar biosynthetic protein fliR
FIV04_RS04215	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
FIV04_RS04220	COG0643	Histidine kinase
FIV04_RS04220	COG0784	Response regulator, receiver
FIV04_RS04220	COG2198	Histidine kinase
FIV04_RS04225	COG2201	protein-glutamate methylesterase activity
FIV04_RS04230	COG1192	Involved in chromosome partitioning
FIV04_RS04240	COG0835	chemotaxis
FIV04_RS04250	COG4133	protoheme IX ABC transporter activity
FIV04_RS04255	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FIV04_RS04260	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FIV04_RS04265	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FIV04_RS04270	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
FIV04_RS04275	COG1138	Cytochrome C-type biogenesis protein
FIV04_RS04280	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FIV04_RS04285	COG3088	subunit of a heme lyase
FIV04_RS04285	COG4235	cytochrome complex assembly
FIV04_RS04295	COG2853	Lipoprotein
FIV04_RS04305	COG2067	long-chain fatty acid transport protein
FIV04_RS04320	COG0183	Belongs to the thiolase family
FIV04_RS04330	COG1025	Belongs to the peptidase M16 family
FIV04_RS04335	COG2062	phosphohistidine phosphatase, SixA
FIV04_RS04340	COG2840	Smr protein MutS2
FIV04_RS04345	COG2890	protein-(glutamine-N5) methyltransferase activity
FIV04_RS04350	COG1280	lysine exporter protein (LysE YggA)
FIV04_RS04355	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FIV04_RS04370	COG1653	transport
FIV04_RS04375	COG1175	transmembrane transport
FIV04_RS04385	COG3842	ATPase activity
FIV04_RS04390	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FIV04_RS04395	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FIV04_RS04400	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FIV04_RS04410	COG2204	response regulator
FIV04_RS04425	COG0544	peptidyl-prolyl cis-trans isomerase activity
FIV04_RS04430	COG0740	serine-type endopeptidase activity
FIV04_RS04435	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FIV04_RS04440	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FIV04_RS04445	COG0776	regulation of translation
FIV04_RS04450	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FIV04_RS04455	COG1555	photosystem II stabilization
FIV04_RS04470	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FIV04_RS04475	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
FIV04_RS04480	COG0436	Aminotransferase
FIV04_RS04485	COG1169	isochorismate synthase
FIV04_RS04490	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
FIV04_RS04515	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FIV04_RS04515	COG1263	PTS System
FIV04_RS04515	COG2190	(PTS) system
FIV04_RS04525	COG2855	membrane
FIV04_RS04530	COG0477	Major facilitator Superfamily
FIV04_RS04585	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FIV04_RS04590	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FIV04_RS04595	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
FIV04_RS04605	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FIV04_RS04610	COG1522	sequence-specific DNA binding
FIV04_RS04620	COG1946	Acyl-CoA thioesterase
FIV04_RS04625	COG3126	Type III secretion system lipoprotein chaperone (YscW)
FIV04_RS04645	COG2188	Transcriptional regulator
FIV04_RS04650	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FIV04_RS04650	COG1263	PTS System
FIV04_RS04655	COG1621	beta-fructofuranosidase activity
FIV04_RS04665	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FIV04_RS04685	COG2203	Gaf domain
FIV04_RS04685	COG4251	negative regulation of phosphorylation
FIV04_RS04685	COG5001	Diguanylate cyclase
FIV04_RS04685	COG3706	GGDEF domain
FIV04_RS04715	COG2824	Alkylphosphonate utilization operon protein PhnA
FIV04_RS04730	COG5002	protein histidine kinase activity
FIV04_RS04730	COG0784	Response regulator, receiver
FIV04_RS04735	COG0745	RESPONSE REGULATOR receiver
FIV04_RS04795	COG3119	arylsulfatase activity
FIV04_RS04800	COG1609	Transcriptional regulator
FIV04_RS04815	COG2814	Major facilitator Superfamily
FIV04_RS04825	COG1760	l-serine dehydratase
FIV04_RS04830	COG1522	sequence-specific DNA binding
FIV04_RS04840	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FIV04_RS04850	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FIV04_RS04860	COG1228	amidohydrolase
FIV04_RS04865	COG3040	lipid binding
FIV04_RS04895	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FIV04_RS04915	COG0583	DNA-binding transcription factor activity
FIV04_RS04920	COG0346	lactoylglutathione lyase activity
FIV04_RS04925	COG1902	pentaerythritol trinitrate reductase activity
FIV04_RS04950	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FIV04_RS04975	COG0517	IMP dehydrogenase activity
FIV04_RS04975	COG0617	tRNA 3'-terminal CCA addition
FIV04_RS04975	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FIV04_RS04985	COG2217	Heavy metal translocating P-type atpase
FIV04_RS05005	COG0537	adenosine 5'-monophosphoramidase activity
FIV04_RS05030	COG3150	esterase
FIV04_RS05035	COG1252	NADH dehydrogenase
FIV04_RS05040	COG1028	Short-chain dehydrogenase reductase Sdr
FIV04_RS05045	COG0616	signal peptide processing
FIV04_RS05050	COG2719	SpoVR family
FIV04_RS05055	COG2718	Belongs to the UPF0229 family
FIV04_RS05060	COG2766	serine protein kinase
FIV04_RS05070	COG3013	Belongs to the UPF0304 family
FIV04_RS05075	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FIV04_RS05085	COG1882	Formate acetyltransferase
FIV04_RS05130	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FIV04_RS05145	COG1770	oligopeptidase
FIV04_RS05150	COG2814	Major facilitator Superfamily
FIV04_RS05155	COG0840	transmembrane signaling receptor activity
FIV04_RS05160	COG2850	peptidyl-arginine hydroxylation
FIV04_RS05175	COG0730	response to heat
FIV04_RS05180	COG1199	ATP-dependent helicase activity
FIV04_RS05190	COG1187	pseudouridine synthase activity
FIV04_RS05200	COG1278	Cold shock
FIV04_RS05205	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FIV04_RS05210	COG0542	response to heat
FIV04_RS05215	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FIV04_RS05220	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FIV04_RS05225	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FIV04_RS05235	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FIV04_RS05245	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FIV04_RS05250	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FIV04_RS05255	COG0297	glycogen (starch) synthase activity
FIV04_RS05275	COG3070	regulator of competence-specific genes
FIV04_RS05280	COG1609	Transcriptional regulator
FIV04_RS05285	COG3381	protein complex oligomerization
FIV04_RS05290	COG0745	RESPONSE REGULATOR receiver
FIV04_RS05295	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FIV04_RS05300	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FIV04_RS05305	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
FIV04_RS05310	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
FIV04_RS05315	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FIV04_RS05320	COG3383	formate dehydrogenase (NAD+) activity
FIV04_RS05335	COG0189	ligase activity
FIV04_RS05335	COG4067	protein conserved in archaea
FIV04_RS05340	COG0500	methyltransferase
FIV04_RS05345	COG4106	trans-aconitate 2-methyltransferase activity
FIV04_RS05350	COG1801	Protein of unknown function DUF72
FIV04_RS05360	COG2203	Gaf domain
FIV04_RS05360	COG2199	diguanylate cyclase activity
FIV04_RS05370	COG0840	transmembrane signaling receptor activity
FIV04_RS05375	COG0632	four-way junction helicase activity
FIV04_RS05380	COG2255	four-way junction helicase activity
FIV04_RS05385	COG1271	oxidase subunit
FIV04_RS05390	COG1294	oxidase, subunit
FIV04_RS05395	COG4890	Cyd operon protein YbgT
FIV04_RS05405	COG0824	Thioesterase
FIV04_RS05410	COG0811	peptide transport
FIV04_RS05425	COG0823	Involved in the tonB-independent uptake of proteins
FIV04_RS05430	COG2885	chlorophyll binding
FIV04_RS05435	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
FIV04_RS05440	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FIV04_RS05455	COG0784	Response regulator, receiver
FIV04_RS05455	COG5002	protein histidine kinase activity
FIV04_RS05480	COG1175	transmembrane transport
FIV04_RS05485	COG0395	ABC-type sugar transport system, permease component
FIV04_RS05490	COG1554	hydrolase, family 65, central catalytic
FIV04_RS05495	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FIV04_RS05500	COG3842	ATPase activity
FIV04_RS05510	COG1621	beta-fructofuranosidase activity
FIV04_RS05530	COG0583	DNA-binding transcription factor activity
FIV04_RS05535	COG1349	DNA-binding transcription factor activity
FIV04_RS05540	COG0584	glycerophosphoryl diester phosphodiesterase
FIV04_RS05555	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FIV04_RS05595	COG3710	Transcriptional regulator
FIV04_RS05600	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FIV04_RS05615	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FIV04_RS05635	COG0745	RESPONSE REGULATOR receiver
FIV04_RS05640	COG0463	Glycosyl transferase, family 2
FIV04_RS05655	COG1032	radical SAM domain protein
FIV04_RS05675	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FIV04_RS05685	COG2350	Protein conserved in bacteria
FIV04_RS05690	COG1607	acyl-coa hydrolase
FIV04_RS05695	COG2917	probably involved in intracellular septation
FIV04_RS05720	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FIV04_RS05725	COG0840	transmembrane signaling receptor activity
FIV04_RS05745	COG1301	dicarboxylic acid transport
FIV04_RS05755	COG0330	HflC and HflK could
FIV04_RS05760	COG0159	tryptophan synthase activity
FIV04_RS05770	COG0135	phosphoribosylanthranilate isomerase activity
FIV04_RS05770	COG0134	indole-3-glycerol-phosphate synthase activity
FIV04_RS05775	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FIV04_RS05780	COG0512	Glutamine amidotransferase of anthranilate synthase
FIV04_RS05785	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FIV04_RS05800	COG0009	L-threonylcarbamoyladenylate synthase
FIV04_RS05805	COG1187	pseudouridine synthase activity
FIV04_RS05820	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FIV04_RS05830	COG0417	DNA replication proofreading
FIV04_RS05835	COG2197	response regulator
FIV04_RS05840	COG0322	excinuclease ABC activity
FIV04_RS05885	COG0019	diaminopimelate decarboxylase activity
FIV04_RS05920	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FIV04_RS05925	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FIV04_RS05935	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FIV04_RS05950	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FIV04_RS05955	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
FIV04_RS05965	COG0437	4 iron, 4 sulfur cluster binding
FIV04_RS05970	COG3301	Polysulphide reductase, NrfD
FIV04_RS05975	COG1138	Cytochrome C-type biogenesis protein
FIV04_RS05985	COG3088	subunit of a heme lyase
FIV04_RS05985	COG4235	cytochrome complex assembly
FIV04_RS05990	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FIV04_RS06015	COG2989	Protein conserved in bacteria
FIV04_RS06020	COG3108	Peptidase M15
FIV04_RS06025	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FIV04_RS06040	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FIV04_RS06065	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FIV04_RS06070	COG0840	transmembrane signaling receptor activity
FIV04_RS06080	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
FIV04_RS06090	COG2166	iron-sulfur cluster assembly
FIV04_RS06095	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FIV04_RS06100	COG0719	Fe-S assembly protein
FIV04_RS06105	COG0396	ATPase activity
FIV04_RS06110	COG0719	Fe-S assembly protein
FIV04_RS06115	COG0316	Belongs to the HesB IscA family
FIV04_RS06125	COG1780	Probably involved in ribonucleotide reductase function
FIV04_RS06130	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FIV04_RS06145	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FIV04_RS06150	COG4988	ABC transporter
FIV04_RS06155	COG0492	ferredoxin-NADP+ reductase activity
FIV04_RS06170	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FIV04_RS06205	COG0471	metal ion transport
FIV04_RS06210	COG2949	membrane
FIV04_RS06215	COG0281	malic enzyme
FIV04_RS06220	COG1643	Atp-dependent helicase
FIV04_RS06230	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FIV04_RS06265	COG0247	lactate metabolic process
FIV04_RS06265	COG0277	FAD linked oxidase domain protein
FIV04_RS06280	COG2986	histidine ammonia-lyase
FIV04_RS06285	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FIV04_RS06290	COG0010	Belongs to the arginase family
FIV04_RS06295	COG1228	amidohydrolase
FIV04_RS06300	COG2188	Transcriptional regulator
FIV04_RS06305	COG4326	sporulation control protein
FIV04_RS06315	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FIV04_RS06325	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FIV04_RS06330	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FIV04_RS06335	COG3097	Belongs to the UPF0267 family
FIV04_RS06350	COG1794	racemase activity, acting on amino acids and derivatives
FIV04_RS06355	COG1309	transcriptional regulator
FIV04_RS06365	COG1166	arginine decarboxylase activity
FIV04_RS06385	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FIV04_RS06395	COG0534	Mate efflux family protein
FIV04_RS06400	COG0444	Belongs to the ABC transporter superfamily
FIV04_RS06405	COG4608	Belongs to the ABC transporter superfamily
FIV04_RS06425	COG3713	MltA-interacting MipA family protein
FIV04_RS06430	COG5001	Diguanylate cyclase
FIV04_RS06455	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
FIV04_RS06460	COG1280	lysine exporter protein (LysE YggA)
FIV04_RS06465	COG1115	amino acid carrier protein
FIV04_RS06475	COG1115	amino acid carrier protein
FIV04_RS06490	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FIV04_RS06505	COG3290	protein histidine kinase activity
FIV04_RS06510	COG4565	transcriptional regulatory protein
FIV04_RS06515	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FIV04_RS06520	COG0363	glucosamine-6-phosphate deaminase activity
FIV04_RS06525	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FIV04_RS06535	COG4628	conserved protein (DUF2132)
FIV04_RS06565	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FIV04_RS06570	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FIV04_RS06580	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FIV04_RS06585	COG0372	Belongs to the citrate synthase family
FIV04_RS06590	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FIV04_RS06595	COG2828	Protein conserved in bacteria
FIV04_RS06615	COG0561	phosphatase activity
FIV04_RS06620	COG0602	queuosine metabolic process
FIV04_RS06625	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FIV04_RS06640	COG3047	cAMP biosynthetic process
FIV04_RS06640	COG2885	chlorophyll binding
FIV04_RS06665	COG1254	Belongs to the acylphosphatase family
FIV04_RS06670	COG2920	part of a sulfur-relay system
FIV04_RS06675	COG0670	Belongs to the BI1 family
FIV04_RS06680	COG1126	abc transporter atp-binding protein
FIV04_RS06685	COG0765	amino acid transport
FIV04_RS06690	COG4597	amino acid ABC transporter
FIV04_RS06695	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FIV04_RS06705	COG1666	GTP binding
FIV04_RS06710	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FIV04_RS06725	COG2996	Protein conserved in bacteria
FIV04_RS06730	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FIV04_RS06730	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
FIV04_RS06735	COG3008	intermembrane lipid transfer
FIV04_RS06740	COG2995	paraquat-inducible protein a
FIV04_RS06745	COG1132	(ABC) transporter
FIV04_RS06750	COG1956	GAF domain-containing protein
FIV04_RS06755	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
FIV04_RS06770	COG0308	aminopeptidase N
FIV04_RS06780	COG2902	Dehydrogenase
FIV04_RS06785	COG0167	dihydroorotate dehydrogenase activity
FIV04_RS06805	COG0488	(ABC) transporter
FIV04_RS06825	COG1067	ATP-dependent peptidase activity
FIV04_RS06830	COG3120	sequence-specific DNA binding
FIV04_RS07160	COG2205	protein histidine kinase activity
FIV04_RS07160	COG0784	Response regulator, receiver
FIV04_RS07175	COG3278	Belongs to the heme-copper respiratory oxidase family
FIV04_RS07190	COG2010	Cytochrome c
FIV04_RS07200	COG2217	Heavy metal translocating P-type atpase
FIV04_RS07215	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FIV04_RS07220	COG0589	response to stress
FIV04_RS07225	COG0037	tRNA processing
FIV04_RS07245	COG3842	ATPase activity
FIV04_RS07255	COG1177	transmembrane transport
FIV04_RS07260	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FIV04_RS07265	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FIV04_RS07270	COG5002	protein histidine kinase activity
FIV04_RS07270	COG5001	Diguanylate cyclase
FIV04_RS07275	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FIV04_RS07280	COG0004	ammonium transporteR
FIV04_RS07295	COG0437	4 iron, 4 sulfur cluster binding
FIV04_RS07300	COG0243	molybdopterin cofactor binding
FIV04_RS07300	COG3383	formate dehydrogenase (NAD+) activity
FIV04_RS07330	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FIV04_RS07335	COG0840	transmembrane signaling receptor activity
FIV04_RS07340	COG0488	(ABC) transporter
FIV04_RS07370	COG4191	Histidine kinase
FIV04_RS07375	COG2204	response regulator
FIV04_RS07385	COG4662	Binding-protein-dependent transport system inner membrane component
FIV04_RS07390	COG3842	ATPase activity
FIV04_RS07395	COG0746	molybdenum cofactor guanylyltransferase activity
FIV04_RS07410	COG1940	carbohydrate kinase activity
FIV04_RS07415	COG3148	PFAM DTW domain containing protein
FIV04_RS07430	COG0791	NLP P60 protein
FIV04_RS07450	COG0307	riboflavin synthase, alpha
FIV04_RS07455	COG0534	Mate efflux family protein
FIV04_RS07495	COG3448	diguanylate cyclase activity
FIV04_RS07495	COG4175	Glycine betaine
FIV04_RS07505	COG2204	response regulator
FIV04_RS07510	COG0438	transferase activity, transferring glycosyl groups
FIV04_RS07515	COG0297	glycogen (starch) synthase activity
FIV04_RS07540	COG0438	transferase activity, transferring glycosyl groups
FIV04_RS07555	COG1215	transferase activity, transferring glycosyl groups
FIV04_RS07560	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FIV04_RS07565	COG0583	DNA-binding transcription factor activity
FIV04_RS07570	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FIV04_RS07595	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FIV04_RS07600	COG0110	maltose O-acetyltransferase activity
FIV04_RS07620	COG4160	amino acid transport
FIV04_RS07625	COG4215	(ABC) transporter
FIV04_RS07630	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FIV04_RS07635	COG1126	abc transporter atp-binding protein
FIV04_RS07640	COG1132	(ABC) transporter
FIV04_RS07665	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FIV04_RS07675	COG1609	Transcriptional regulator
FIV04_RS07680	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FIV04_RS07690	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FIV04_RS07690	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FIV04_RS07695	COG3842	ATPase activity
FIV04_RS07705	COG1175	transmembrane transport
FIV04_RS07710	COG0395	ABC-type sugar transport system, permease component
FIV04_RS07730	COG0826	peptidase U32
FIV04_RS07765	COG0589	response to stress
FIV04_RS07770	COG0415	Belongs to the DNA photolyase family
FIV04_RS07775	COG3046	protein related to deoxyribodipyrimidine photolyase
FIV04_RS07790	COG0419	ATPase involved in DNA repair
FIV04_RS07795	COG0420	3'-5' exonuclease activity
FIV04_RS07820	COG1917	Cupin 2, conserved barrel domain protein
FIV04_RS07825	COG1028	Short-chain dehydrogenase reductase Sdr
FIV04_RS07830	COG0517	IMP dehydrogenase activity
FIV04_RS07835	COG2176	DNA-directed DNA polymerase activity
FIV04_RS07840	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FIV04_RS07855	COG1472	Belongs to the glycosyl hydrolase 3 family
FIV04_RS07865	COG0454	-acetyltransferase
FIV04_RS07870	COG4771	TonB-dependent receptor
FIV04_RS07875	COG0583	DNA-binding transcription factor activity
FIV04_RS07885	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FIV04_RS07890	COG2197	response regulator
FIV04_RS07910	COG3469	chitinase activity
FIV04_RS07915	COG4943	cyclic-guanylate-specific phosphodiesterase activity
FIV04_RS07925	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FIV04_RS07930	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FIV04_RS07935	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FIV04_RS07940	COG1012	belongs to the aldehyde dehydrogenase family
FIV04_RS07950	COG0579	oxidoreductase
FIV04_RS07965	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FIV04_RS07995	COG2195	Cleaves the N-terminal amino acid of tripeptides
FIV04_RS08015	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FIV04_RS08020	COG3063	Type IV pilus biogenesis stability protein PilW
FIV04_RS08030	COG1451	nucleotide metabolic process
FIV04_RS08045	COG2814	Major facilitator Superfamily
FIV04_RS08065	COG1247	-acetyltransferase
FIV04_RS08070	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
FIV04_RS08075	COG4139	cobalamin transport
FIV04_RS08080	COG2988	succinylglutamate desuccinylase activity
FIV04_RS08100	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FIV04_RS08105	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FIV04_RS08110	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FIV04_RS08115	COG0702	epimerase
FIV04_RS08120	COG1823	symporter activity
FIV04_RS08125	COG3193	protein, possibly involved in utilization of glycolate and propanediol
FIV04_RS08130	COG4989	oxidoreductase activity
FIV04_RS08145	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FIV04_RS08150	COG3122	Protein conserved in bacteria
FIV04_RS08155	COG2207	Transcriptional regulator
FIV04_RS08175	COG2925	Exonuclease
FIV04_RS08185	COG1346	cytolysis
FIV04_RS08190	COG0295	cytidine deaminase activity
FIV04_RS08195	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
FIV04_RS08200	COG0500	methyltransferase
FIV04_RS08215	COG0776	regulation of translation
FIV04_RS08245	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FIV04_RS08250	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FIV04_RS08255	COG1121	(ABC) transporter
FIV04_RS08300	COG1741	Belongs to the pirin family
FIV04_RS08315	COG0583	DNA-binding transcription factor activity
FIV04_RS08320	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FIV04_RS08330	COG1280	lysine exporter protein (LysE YggA)
FIV04_RS08340	COG2873	o-acetylhomoserine
FIV04_RS08345	COG1522	sequence-specific DNA binding
FIV04_RS08390	COG0488	(ABC) transporter
FIV04_RS08420	COG0596	Alpha beta hydrolase
FIV04_RS08430	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FIV04_RS08475	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FIV04_RS08475	COG0072	phenylalanine-tRNA ligase activity
FIV04_RS08480	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FIV04_RS08525	COG1643	Atp-dependent helicase
FIV04_RS08530	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FIV04_RS08545	COG0395	ABC-type sugar transport system, permease component
FIV04_RS08550	COG1175	transmembrane transport
FIV04_RS08555	COG1653	transport
FIV04_RS08565	COG3459	Glycosyltransferase 36 associated
FIV04_RS08570	COG3842	ATPase activity
FIV04_RS08610	COG3710	Transcriptional regulator
FIV04_RS08640	COG3706	GGDEF domain
FIV04_RS08650	COG0443	Heat shock 70 kDa protein
FIV04_RS08655	COG0443	Heat shock 70 kDa protein
FIV04_RS08670	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FIV04_RS08680	COG3768	UPF0283 membrane protein
FIV04_RS08685	COG3106	COG3106 Predicted ATPase
FIV04_RS08700	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FIV04_RS08705	COG0784	Response regulator, receiver
FIV04_RS08705	COG2205	protein histidine kinase activity
FIV04_RS08715	COG0494	nUDIX hydrolase
FIV04_RS08720	COG0814	amino acid
FIV04_RS08725	COG1760	l-serine dehydratase
FIV04_RS08730	COG0814	amino acid
FIV04_RS08735	COG0840	transmembrane signaling receptor activity
FIV04_RS08740	COG0017	Asparaginyl-tRNA synthetase
FIV04_RS08760	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FIV04_RS08770	COG3437	response regulator, receiver
FIV04_RS08770	COG2770	Histidine kinase
FIV04_RS08775	COG1448	Aminotransferase
FIV04_RS08795	COG2199	diguanylate cyclase activity
FIV04_RS08805	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FIV04_RS08815	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FIV04_RS08815	COG4191	Histidine kinase
FIV04_RS08830	COG3070	regulator of competence-specific genes
FIV04_RS08840	COG2431	L-lysine efflux transmembrane transporter activity
FIV04_RS08850	COG0076	glutamate decarboxylase activity
FIV04_RS08855	COG1737	Transcriptional regulator
FIV04_RS08865	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FIV04_RS08870	COG2985	domain, Protein
FIV04_RS08870	COG3273	potassium ion transport
FIV04_RS08885	COG1960	acyl-CoA dehydrogenase activity
FIV04_RS08905	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FIV04_RS08920	COG4181	ATPase activity
FIV04_RS08925	COG0534	Mate efflux family protein
FIV04_RS08930	COG1858	cytochrome C peroxidase
FIV04_RS08935	COG0702	epimerase
FIV04_RS08945	COG2814	Major facilitator Superfamily
FIV04_RS08955	COG1061	Type III restriction enzyme res subunit
FIV04_RS08970	COG2205	protein histidine kinase activity
FIV04_RS08980	COG0612	Peptidase, M16
FIV04_RS08985	COG4178	(ABC) transporter
FIV04_RS08990	COG4771	TonB-dependent receptor
FIV04_RS09000	COG0811	peptide transport
FIV04_RS09005	COG0811	peptide transport
FIV04_RS09010	COG0848	biopolymer transport protein
FIV04_RS09030	COG0463	Glycosyl transferase, family 2
FIV04_RS09030	COG1216	Glycosyl transferase, family 2
FIV04_RS09035	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FIV04_RS09130	COG0523	cobalamin synthesis protein
FIV04_RS09140	COG0384	phenazine biosynthesis protein PhzF
FIV04_RS09155	COG3264	Mechanosensitive ion channel
FIV04_RS09155	COG1511	domain protein
FIV04_RS09165	COG0583	DNA-binding transcription factor activity
FIV04_RS09180	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FIV04_RS09180	COG3008	intermembrane lipid transfer
FIV04_RS09185	COG2995	paraquat-inducible protein a
FIV04_RS09215	COG4774	siderophore transport
FIV04_RS09225	COG0243	molybdopterin cofactor binding
FIV04_RS09230	COG3005	denitrification pathway
FIV04_RS09240	COG2866	Carboxypeptidase
FIV04_RS09250	COG0513	Belongs to the DEAD box helicase family
FIV04_RS09260	COG3313	Fe-S protein
FIV04_RS09270	COG4134	Bacterial extracellular solute-binding protein
FIV04_RS09275	COG4135	transport system, permease component
FIV04_RS09280	COG4136	ATPase activity
FIV04_RS09285	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FIV04_RS09290	COG0116	Belongs to the methyltransferase superfamily
FIV04_RS09290	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FIV04_RS09295	COG0564	pseudouridine synthase activity
FIV04_RS09305	COG0733	neurotransmitter:sodium symporter activity
FIV04_RS09315	COG0626	cystathionine gamma-synthase activity
FIV04_RS09330	COG2818	Glycosylase
FIV04_RS09345	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FIV04_RS09350	COG1983	PspC domain protein
FIV04_RS09360	COG1842	Phage shock protein A
FIV04_RS09365	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
FIV04_RS09380	COG4171	peptide transport system, permease
FIV04_RS09390	COG4172	Belongs to the ABC transporter superfamily
FIV04_RS09405	COG1227	inorganic diphosphatase activity
FIV04_RS09415	COG0243	molybdopterin cofactor binding
FIV04_RS09420	COG3005	denitrification pathway
FIV04_RS09425	COG4459	periplasmic nitrate reductase
FIV04_RS09430	COG0390	transport system, permease component
FIV04_RS09435	COG2116	formate transmembrane transporter activity
FIV04_RS09465	COG0215	cysteine-tRNA ligase activity
FIV04_RS09470	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FIV04_RS09475	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FIV04_RS09480	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FIV04_RS09485	COG3012	SEC-C Motif Domain Protein
FIV04_RS09490	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FIV04_RS09490	COG0140	phosphoribosyl-ATP diphosphatase activity
FIV04_RS09500	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FIV04_RS09505	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FIV04_RS09510	COG0131	Imidazoleglycerol-phosphate dehydratase
FIV04_RS09510	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FIV04_RS09530	COG1757	Na H antiporter
FIV04_RS09535	COG2916	Histone family protein nucleoid-structuring protein H-NS
FIV04_RS09540	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FIV04_RS09555	COG2915	High frequency lysogenization protein hflD homolog
FIV04_RS09560	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FIV04_RS09565	COG0501	Belongs to the peptidase M48B family
FIV04_RS09575	COG2226	methyltransferase
FIV04_RS09580	COG0156	8-amino-7-oxononanoate synthase activity
FIV04_RS09585	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FIV04_RS09590	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FIV04_RS09595	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FIV04_RS09600	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FIV04_RS09605	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FIV04_RS09610	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FIV04_RS09615	COG1674	ftsk spoiiie
FIV04_RS09620	COG1522	sequence-specific DNA binding
FIV04_RS09625	COG0686	Belongs to the AlaDH PNT family
FIV04_RS09635	COG0583	DNA-binding transcription factor activity
FIV04_RS09660	COG4608	Belongs to the ABC transporter superfamily
FIV04_RS09665	COG0444	Belongs to the ABC transporter superfamily
FIV04_RS09670	COG4166	transmembrane transport
FIV04_RS09675	COG4239	(ABC) transporter, permease
FIV04_RS09680	COG4174	ABC transporter (Permease)
FIV04_RS09685	COG0284	orotidine-5'-phosphate decarboxylase activity
FIV04_RS09690	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
FIV04_RS09695	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
FIV04_RS09700	COG0776	regulation of translation
FIV04_RS09705	COG0539	negative regulation of cytoplasmic translation
FIV04_RS09710	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FIV04_RS09715	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FIV04_RS09720	COG2835	tetraacyldisaccharide 4'-kinase activity
FIV04_RS09725	COG1663	tetraacyldisaccharide 4'-kinase activity
FIV04_RS09730	COG1132	(ABC) transporter
FIV04_RS09735	COG0658	competence protein
FIV04_RS09735	COG2333	competence protein COMEC
FIV04_RS09745	COG4591	ABC-type transport system involved in lipoprotein release permease component
FIV04_RS09750	COG1136	(ABC) transporter
FIV04_RS09755	COG4591	ABC-type transport system involved in lipoprotein release permease component
FIV04_RS09765	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FIV04_RS09775	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FIV04_RS09790	COG0587	DNA-directed DNA polymerase activity
FIV04_RS09795	COG0835	chemotaxis
FIV04_RS09795	COG0784	Response regulator, receiver
FIV04_RS09800	COG1940	carbohydrate kinase activity
FIV04_RS09805	COG0469	pyruvate kinase activity
FIV04_RS09810	COG4667	esterase of the alpha-beta hydrolase superfamily
FIV04_RS09830	COG1263	PTS System
FIV04_RS09830	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FIV04_RS09835	COG0084	hydrolase, TatD family'
FIV04_RS09840	COG0470	DNA polymerase III
FIV04_RS09845	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FIV04_RS09850	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FIV04_RS09855	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FIV04_RS09880	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FIV04_RS09885	COG0416	fatty acid biosynthetic process
FIV04_RS09890	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FIV04_RS09895	COG1399	metal-binding, possibly nucleic acid-binding protein
FIV04_RS09900	COG0424	maF-like protein
FIV04_RS09905	COG0564	pseudouridine synthase activity
FIV04_RS09910	COG1530	ribonuclease E activity
FIV04_RS09915	COG0659	secondary active sulfate transmembrane transporter activity
FIV04_RS09925	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
FIV04_RS09930	COG2982	Protein involved in outer membrane biogenesis
FIV04_RS09935	COG0572	uridine kinase
FIV04_RS09940	COG0489	protein tyrosine kinase activity
FIV04_RS09955	COG2186	Transcriptional regulator
FIV04_RS09960	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FIV04_RS09970	COG0653	protein targeting
FIV04_RS09975	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FIV04_RS09980	COG3706	GGDEF domain
FIV04_RS09985	COG0366	Alpha amylase catalytic
FIV04_RS09995	COG3092	negative regulation of chromosome organization
FIV04_RS10000	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FIV04_RS10005	COG0857	belongs to the CobB CobQ family
FIV04_RS10005	COG0280	phosphate acetyltransferase
FIV04_RS10010	COG0435	Glutathione S-transferase
FIV04_RS10020	COG0444	Belongs to the ABC transporter superfamily
FIV04_RS10025	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FIV04_RS10030	COG0601	transmembrane transport
FIV04_RS10040	COG0314	molybdopterin synthase activity
FIV04_RS10045	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FIV04_RS10055	COG0521	Mo-molybdopterin cofactor biosynthetic process
FIV04_RS10060	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FIV04_RS10065	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FIV04_RS10070	COG2198	Histidine kinase
FIV04_RS10075	COG2204	response regulator
FIV04_RS10080	COG0556	nucleotide-excision repair
FIV04_RS10090	COG4657	Part of a membrane complex involved in electron transport
FIV04_RS10095	COG2878	Part of a membrane complex involved in electron transport
FIV04_RS10100	COG4656	Part of a membrane complex involved in electron transport
FIV04_RS10105	COG4658	electron transport chain
FIV04_RS10110	COG4659	FMN binding
FIV04_RS10115	COG4660	Part of a membrane complex involved in electron transport
FIV04_RS10120	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FIV04_RS10125	COG0346	lactoylglutathione lyase activity
FIV04_RS10145	COG2056	Na+-H+ antiporter family
FIV04_RS10155	COG2205	protein histidine kinase activity
FIV04_RS10155	COG0784	Response regulator, receiver
FIV04_RS10155	COG5002	protein histidine kinase activity
FIV04_RS10165	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FIV04_RS10185	COG1012	belongs to the aldehyde dehydrogenase family
FIV04_RS10185	COG1454	alcohol dehydrogenase
FIV04_RS10190	COG2095	MarC family integral membrane protein
FIV04_RS10195	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FIV04_RS10200	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FIV04_RS10205	COG1757	Na H antiporter
FIV04_RS10215	COG3081	Nucleoid-associated protein
FIV04_RS10220	COG3082	Protein of unknown function (DUF1414)
FIV04_RS10225	COG3083	sulfuric ester hydrolase activity
FIV04_RS10240	COG0123	including yeast histone deacetylase and acetoin utilization protein
FIV04_RS10255	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FIV04_RS10260	COG0778	Nitroreductase
FIV04_RS10265	COG0446	pyridine nucleotide-disulphide oxidoreductase
FIV04_RS10265	COG1902	pentaerythritol trinitrate reductase activity
FIV04_RS10270	COG0616	signal peptide processing
FIV04_RS10275	COG0252	asparaginase activity
FIV04_RS10280	COG3139	Protein of unknown function (DUF1315)
FIV04_RS10290	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FIV04_RS10310	COG2226	methyltransferase
FIV04_RS10330	COG2983	Belongs to the UPF0260 family
FIV04_RS10340	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FIV04_RS10350	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FIV04_RS10355	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FIV04_RS10360	COG2832	Protein of unknown function (DUF454)
FIV04_RS10365	COG0745	RESPONSE REGULATOR receiver
FIV04_RS10370	COG0583	DNA-binding transcription factor activity
FIV04_RS10375	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FIV04_RS10380	COG1286	toxin biosynthetic process
FIV04_RS10385	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
FIV04_RS10390	COG0285	dihydrofolate synthase activity
FIV04_RS10395	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FIV04_RS10405	COG0101	tRNA pseudouridine synthase activity
FIV04_RS10415	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FIV04_RS10420	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FIV04_RS10425	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FIV04_RS10435	COG0431	NADPH-dependent FMN reductase
FIV04_RS10445	COG3101	peptidyl-lysine hydroxylation
FIV04_RS10450	COG2860	membrane
FIV04_RS10455	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FIV04_RS10470	COG2815	serine threonine protein kinase
FIV04_RS10470	COG0515	serine threonine protein kinase
FIV04_RS10480	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FIV04_RS10485	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FIV04_RS10495	COG2951	lytic endotransglycosylase activity
FIV04_RS10500	COG3100	YcgL domain-containing protein
FIV04_RS10505	COG0850	regulation of cytokinetic process
FIV04_RS10510	COG2894	cell division
FIV04_RS10515	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FIV04_RS10525	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FIV04_RS10530	COG0318	PFAM AMP-dependent synthetase and ligase
FIV04_RS10540	COG3065	identical protein binding
FIV04_RS10550	COG1214	PFAM Peptidase M22, glycoprotease
FIV04_RS10555	COG1199	ATP-dependent helicase activity
FIV04_RS10560	COG0788	formyltetrahydrofolate deformylase activity
FIV04_RS10565	COG3102	Protein conserved in bacteria
FIV04_RS10590	COG1918	ferrous iron import across plasma membrane
FIV04_RS10605	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
FIV04_RS10610	COG1121	(ABC) transporter
FIV04_RS10615	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FIV04_RS10625	COG0045	succinate-CoA ligase (ADP-forming) activity
FIV04_RS10630	COG0508	dehydrogenase complex catalyzes the overall conversion of
FIV04_RS10635	COG0567	Dehydrogenase, E1 component
FIV04_RS10640	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FIV04_RS10645	COG1053	succinate dehydrogenase
FIV04_RS10650	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FIV04_RS10665	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FIV04_RS10675	COG0033	Phosphoglucomutase
FIV04_RS10680	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
FIV04_RS10685	COG0596	Alpha beta hydrolase
FIV04_RS10715	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FIV04_RS10720	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FIV04_RS10720	COG2190	(PTS) system
FIV04_RS10720	COG1263	PTS System
FIV04_RS10725	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FIV04_RS10730	COG1940	carbohydrate kinase activity
FIV04_RS10730	COG1846	Transcriptional regulator
FIV04_RS10735	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FIV04_RS10735	COG4651	solute:proton antiporter activity
FIV04_RS10740	COG0367	asparagine synthase
FIV04_RS10745	COG0250	Participates in transcription elongation, termination and antitermination
FIV04_RS10750	COG3104	oligopeptide transport
FIV04_RS10755	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FIV04_RS10760	COG0563	adenylate kinase activity
FIV04_RS10765	COG0326	Molecular chaperone. Has ATPase activity
FIV04_RS10770	COG3710	Transcriptional regulator
FIV04_RS10785	COG0622	Phosphoesterase
FIV04_RS10810	COG1090	epimerase
FIV04_RS10815	COG0300	oxidoreductase activity
FIV04_RS10820	COG3118	belongs to the thioredoxin family
FIV04_RS10825	COG0330	HflC and HflK could
FIV04_RS10835	COG0789	Transcriptional regulator
FIV04_RS10855	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FIV04_RS10860	COG3115	cell septum assembly
FIV04_RS10865	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
FIV04_RS10880	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FIV04_RS10885	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FIV04_RS10890	COG2190	(PTS) system
FIV04_RS10895	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FIV04_RS10900	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FIV04_RS10905	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FIV04_RS10910	COG2837	iron assimilation
FIV04_RS10935	COG1393	Belongs to the ArsC family
FIV04_RS10940	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FIV04_RS10945	COG1876	peptidase activity
FIV04_RS10955	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
FIV04_RS10960	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FIV04_RS10965	COG2716	regulation of RNA biosynthetic process
FIV04_RS10970	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FIV04_RS10985	COG4783	chaperone-mediated protein folding
FIV04_RS10990	COG1393	Belongs to the ArsC family
FIV04_RS11010	COG2233	PERMEase
FIV04_RS11020	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FIV04_RS11025	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FIV04_RS11030	COG0121	glutamine amidotransferase
FIV04_RS11035	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FIV04_RS11040	COG1960	acyl-CoA dehydrogenase activity
FIV04_RS11060	COG2226	methyltransferase
FIV04_RS11065	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FIV04_RS11070	COG1388	LysM domain
FIV04_RS11070	COG0741	lytic transglycosylase activity
FIV04_RS11085	COG0347	Belongs to the P(II) protein family
FIV04_RS11095	COG0037	tRNA processing
FIV04_RS11100	COG0825	malonyl-CoA metabolic process
FIV04_RS11105	COG0587	DNA-directed DNA polymerase activity
FIV04_RS11110	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FIV04_RS11120	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FIV04_RS11125	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FIV04_RS11135	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
FIV04_RS11145	COG0750	zinc metalloprotease
FIV04_RS11155	COG0575	Belongs to the CDS family
FIV04_RS11160	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FIV04_RS11165	COG0233	cytoplasmic translational termination
FIV04_RS11170	COG0528	UMP kinase activity
FIV04_RS11175	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FIV04_RS11185	COG0024	Methionine aminopeptidase
FIV04_RS11190	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FIV04_RS11200	COG0564	pseudouridine synthase activity
FIV04_RS11205	COG3098	single-species biofilm formation
FIV04_RS11230	COG1671	Belongs to the UPF0178 family
FIV04_RS11240	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
FIV04_RS11250	COG0254	rRNA binding
FIV04_RS11255	COG1720	tRNA m6t6A37 methyltransferase activity
FIV04_RS11260	COG0442	prolyl-tRNA aminoacylation
FIV04_RS11290	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FIV04_RS11305	COG0366	Alpha amylase catalytic
FIV04_RS11310	COG1263	PTS System
FIV04_RS11310	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FIV04_RS11315	COG1609	Transcriptional regulator
FIV04_RS11325	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FIV04_RS11330	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FIV04_RS11335	COG2011	ABC-type metal ion transport system permease component
FIV04_RS11340	COG1464	Belongs to the NlpA lipoprotein family
FIV04_RS11345	COG4580	involved in the transport of maltose and maltodextrins
FIV04_RS11350	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
FIV04_RS11360	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FIV04_RS11360	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FIV04_RS11375	COG1611	Belongs to the LOG family
FIV04_RS11380	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FIV04_RS11390	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
FIV04_RS11395	COG2363	Small membrane protein
FIV04_RS11405	COG0583	DNA-binding transcription factor activity
FIV04_RS11410	COG0625	glutathione transferase activity
FIV04_RS11415	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FIV04_RS11415	COG0301	tRNA thio-modification
FIV04_RS11425	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FIV04_RS11430	COG1722	exodeoxyribonuclease VII activity
FIV04_RS11435	COG0142	geranyltranstransferase activity
FIV04_RS11440	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FIV04_RS11450	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FIV04_RS11455	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FIV04_RS11460	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FIV04_RS11480	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FIV04_RS11480	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FIV04_RS11485	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FIV04_RS11490	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FIV04_RS11505	COG1073	alpha beta
FIV04_RS11510	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
FIV04_RS11515	COG2252	PERMEase
FIV04_RS11520	COG2195	Cleaves the N-terminal amino acid of tripeptides
FIV04_RS11540	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FIV04_RS11555	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FIV04_RS11565	COG2017	converts alpha-aldose to the beta-anomer
FIV04_RS11575	COG1085	galactose-1-phosphate uridylyltransferase
FIV04_RS11580	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FIV04_RS11585	COG1609	Transcriptional regulator
FIV04_RS11590	COG3250	beta-galactosidase activity
FIV04_RS11595	COG2731	YhcH YjgK YiaL family protein
FIV04_RS11600	COG0531	amino acid
FIV04_RS11605	COG0531	amino acid
FIV04_RS11615	COG3408	Glycogen debranching enzyme
FIV04_RS11615	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
FIV04_RS11620	COG3250	beta-galactosidase activity
FIV04_RS11630	COG0395	ABC-type sugar transport system, permease component
FIV04_RS11635	COG1175	transmembrane transport
FIV04_RS11645	COG0534	Mate efflux family protein
FIV04_RS11650	COG0583	DNA-binding transcription factor activity
FIV04_RS11655	COG2059	Chromate
FIV04_RS11710	COG4964	Belongs to the GSP D family
FIV04_RS11730	COG1917	Cupin 2, conserved barrel domain protein
FIV04_RS11730	COG4977	sequence-specific DNA binding
FIV04_RS11735	COG1022	Amp-dependent synthetase and ligase
FIV04_RS11745	COG0583	DNA-binding transcription factor activity
FIV04_RS11755	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FIV04_RS11760	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FIV04_RS11770	COG0560	Phosphoserine phosphatase
FIV04_RS11780	COG0813	purine-nucleoside phosphorylase activity
FIV04_RS11790	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FIV04_RS11795	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FIV04_RS11800	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FIV04_RS11805	COG0084	hydrolase, TatD family'
FIV04_RS11810	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FIV04_RS11820	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FIV04_RS11835	COG3153	acetyltransferase
FIV04_RS11840	COG3154	lipid carrier protein
FIV04_RS11850	COG0826	peptidase U32
FIV04_RS11855	COG0826	peptidase U32
FIV04_RS11860	COG0534	Mate efflux family protein
FIV04_RS11880	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FIV04_RS11885	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FIV04_RS11890	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FIV04_RS11900	COG0195	Participates in both transcription termination and antitermination
FIV04_RS11905	COG0779	Required for maturation of 30S ribosomal subunits
FIV04_RS11920	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FIV04_RS11925	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FIV04_RS11930	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FIV04_RS11935	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FIV04_RS11940	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FIV04_RS11945	COG1534	Rna-binding protein
FIV04_RS11950	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FIV04_RS11960	COG2027	D-alanyl-D-alanine carboxypeptidase
FIV04_RS11965	COG2239	Acts as a magnesium transporter
FIV04_RS11975	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FIV04_RS11980	COG0739	heme binding
FIV04_RS11995	COG0316	Belongs to the HesB IscA family
FIV04_RS12000	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FIV04_RS12005	COG0628	permease
FIV04_RS12010	COG2813	Specifically methylates the guanine in position
FIV04_RS12015	COG2205	protein histidine kinase activity
FIV04_RS12015	COG0784	Response regulator, receiver
FIV04_RS12020	COG0747	negative chemotaxis
FIV04_RS12030	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FIV04_RS12035	COG0444	Belongs to the ABC transporter superfamily
FIV04_RS12040	COG4608	Belongs to the ABC transporter superfamily
FIV04_RS12050	COG2971	BadF BadG BcrA BcrD
FIV04_RS12065	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FIV04_RS12070	COG3842	ATPase activity
FIV04_RS12080	COG1840	ABC-type Fe3 transport system, periplasmic component
FIV04_RS12085	COG0004	ammonium transporteR
FIV04_RS12100	COG1049	propionate catabolic process, 2-methylcitrate cycle
FIV04_RS12105	COG1752	Esterase of the alpha-beta hydrolase superfamily
FIV04_RS12110	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FIV04_RS12115	COG1643	Atp-dependent helicase
FIV04_RS12120	COG1489	DNA binding
FIV04_RS12125	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FIV04_RS12140	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FIV04_RS12145	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FIV04_RS12150	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FIV04_RS12155	COG0842	Transport permease protein
FIV04_RS12160	COG1131	(ABC) transporter
FIV04_RS12165	COG0659	secondary active sulfate transmembrane transporter activity
FIV04_RS12170	COG0288	reversible hydration of carbon dioxide
FIV04_RS12185	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FIV04_RS12190	COG0508	dehydrogenase complex catalyzes the overall conversion of
FIV04_RS12195	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FIV04_RS12215	COG0157	Belongs to the NadC ModD family
FIV04_RS12225	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FIV04_RS12230	COG1459	type II secretion system
FIV04_RS12240	COG0237	dephospho-CoA kinase activity
FIV04_RS12245	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
FIV04_RS12265	COG0336	Belongs to the RNA methyltransferase TrmD family
FIV04_RS12270	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FIV04_RS12280	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FIV04_RS12285	COG4137	Cytochrome C assembly protein
FIV04_RS12290	COG4536	flavin adenine dinucleotide binding
FIV04_RS12295	COG1854	S-ribosylhomocysteine lyase activity
FIV04_RS12310	COG0612	Peptidase, M16
FIV04_RS12315	COG1238	metal cluster binding
FIV04_RS12325	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
FIV04_RS12330	COG0511	ligase activity, forming carbon-carbon bonds
FIV04_RS12330	COG5016	pyruvate
FIV04_RS12335	COG3630	sodium ion export across plasma membrane
FIV04_RS12410	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FIV04_RS12420	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FIV04_RS12425	COG1546	Belongs to the CinA family
FIV04_RS12430	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FIV04_RS12435	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FIV04_RS12445	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FIV04_RS12450	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FIV04_RS12455	COG0585	pseudouridine synthase activity
FIV04_RS12465	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FIV04_RS12470	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
FIV04_RS12475	COG0148	phosphopyruvate hydratase activity
FIV04_RS12485	COG3956	TIGRFAM MazG family protein
FIV04_RS12490	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FIV04_RS12495	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FIV04_RS12505	COG2205	protein histidine kinase activity
FIV04_RS12505	COG3437	response regulator, receiver
FIV04_RS12505	COG3850	Histidine kinase
FIV04_RS12505	COG4999	Histidine kinase
FIV04_RS12510	COG0736	holo-[acyl-carrier-protein] synthase activity
FIV04_RS12515	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FIV04_RS12520	COG1381	Involved in DNA repair and RecF pathway recombination
FIV04_RS12525	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FIV04_RS12530	COG0571	ribonuclease III activity
FIV04_RS12540	COG0481	GTPase activity
FIV04_RS12560	COG1595	DNA-templated transcription, initiation
FIV04_RS12565	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FIV04_RS12575	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FIV04_RS12580	COG0354	folic acid binding
FIV04_RS12585	COG0442	prolyl-tRNA aminoacylation
FIV04_RS12595	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FIV04_RS12600	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FIV04_RS12605	COG3079	Belongs to the UPF0149 family
FIV04_RS12610	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
FIV04_RS12620	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FIV04_RS12625	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FIV04_RS12630	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FIV04_RS12650	COG0668	transmembrane transport
FIV04_RS12655	COG0191	fructose-bisphosphate aldolase activity
FIV04_RS12665	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FIV04_RS12690	COG3091	SprT-like family
FIV04_RS12695	COG2356	endonuclease I
FIV04_RS12705	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FIV04_RS12710	COG0189	ligase activity
FIV04_RS12715	COG1678	Uncharacterized ACR, COG1678
FIV04_RS12735	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FIV04_RS12740	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FIV04_RS12745	COG0762	integral membrane protein
FIV04_RS12760	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FIV04_RS12765	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FIV04_RS12770	COG2066	Belongs to the glutaminase family
FIV04_RS12785	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
FIV04_RS12790	COG0741	lytic transglycosylase activity
FIV04_RS12830	COG0840	transmembrane signaling receptor activity
FIV04_RS12900	COG3437	response regulator, receiver
FIV04_RS12910	COG3706	GGDEF domain
FIV04_RS12940	COG0795	lipopolysaccharide-transporting ATPase activity
FIV04_RS12945	COG0795	lipopolysaccharide-transporting ATPase activity
FIV04_RS12950	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FIV04_RS12955	COG2927	DNA polymerase III (CHI subunit)
FIV04_RS12960	COG0525	valine-tRNA ligase activity
FIV04_RS12965	COG4783	chaperone-mediated protein folding
FIV04_RS12970	COG4269	membrane
FIV04_RS13010	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
FIV04_RS13015	COG0251	oxidation-reduction process
FIV04_RS13020	COG0204	Acyl-transferase
FIV04_RS13025	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FIV04_RS13030	COG5007	Belongs to the BolA IbaG family
FIV04_RS13040	COG2854	intermembrane phospholipid transfer
FIV04_RS13045	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FIV04_RS13060	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FIV04_RS13060	COG0517	IMP dehydrogenase activity
FIV04_RS13065	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FIV04_RS13075	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FIV04_RS13080	COG1137	ATPase activity
FIV04_RS13090	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FIV04_RS13095	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FIV04_RS13100	COG1660	Displays ATPase and GTPase activities
FIV04_RS13105	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FIV04_RS13110	COG2239	Acts as a magnesium transporter
FIV04_RS13115	COG0312	modulator of DNA gyrase
FIV04_RS13120	COG3028	Belongs to the UPF0307 family
FIV04_RS13125	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FIV04_RS13130	COG1178	ABC-type Fe3 transport system permease component
FIV04_RS13135	COG4143	(ABC) transporter
FIV04_RS13140	COG0163	prenyltransferase activity
FIV04_RS13145	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FIV04_RS13150	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
FIV04_RS13160	COG2105	PFAM AIG2 family protein
FIV04_RS13165	COG2911	Protein conserved in bacteria
FIV04_RS13170	COG0729	surface antigen
FIV04_RS13175	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FIV04_RS13185	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
FIV04_RS13220	COG0529	Catalyzes the synthesis of activated sulfate
FIV04_RS13225	COG3273	potassium ion transport
FIV04_RS13225	COG0471	metal ion transport
FIV04_RS13230	COG2895	sulfate adenylyltransferase (ATP) activity
FIV04_RS13235	COG0175	sulfate reduction
FIV04_RS13240	COG0737	Belongs to the 5'-nucleotidase family
FIV04_RS13250	COG0189	ligase activity
FIV04_RS13250	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FIV04_RS13285	COG2153	protein acetylation
FIV04_RS13295	COG3266	domain, Protein
FIV04_RS13295	COG3061	Opacity-associated protein A
FIV04_RS13300	COG0545	Peptidyl-prolyl cis-trans isomerase
FIV04_RS13310	COG0203	ribosomal protein L17
FIV04_RS13315	COG0202	RNA polymerase activity
FIV04_RS13320	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FIV04_RS13325	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FIV04_RS13330	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FIV04_RS13335	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FIV04_RS13340	COG0201	protein transport
FIV04_RS13345	COG0200	Binds to the 23S rRNA
FIV04_RS13350	COG1841	ribosomal large subunit assembly
FIV04_RS13355	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FIV04_RS13360	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FIV04_RS13365	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FIV04_RS13370	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FIV04_RS13375	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FIV04_RS13385	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FIV04_RS13395	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FIV04_RS13405	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FIV04_RS13420	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FIV04_RS13425	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FIV04_RS13430	COG0089	rRNA binding
FIV04_RS13435	COG0088	Forms part of the polypeptide exit tunnel
FIV04_RS13440	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FIV04_RS13445	COG0051	transcription antitermination factor activity, RNA binding
FIV04_RS13455	COG2906	2 iron, 2 sulfur cluster binding
FIV04_RS13460	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FIV04_RS13465	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FIV04_RS13485	COG2923	Belongs to the DsrF TusC family
FIV04_RS13495	COG2964	Protein conserved in bacteria
FIV04_RS13500	COG0545	Peptidyl-prolyl cis-trans isomerase
FIV04_RS13510	COG2900	Belongs to the SlyX family
FIV04_RS13515	COG1446	asparaginase
FIV04_RS13520	COG1047	Peptidyl-prolyl cis-trans
FIV04_RS13535	COG2249	NAD(P)H dehydrogenase (quinone) activity
FIV04_RS13540	COG0488	(ABC) transporter
FIV04_RS13550	COG0429	hydrolase of the alpha beta-hydrolase fold
FIV04_RS13555	COG3089	Belongs to the UPF0270 family
FIV04_RS13560	COG3954	Phosphoribulokinase
FIV04_RS13565	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FIV04_RS13575	COG1012	belongs to the aldehyde dehydrogenase family
FIV04_RS13585	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FIV04_RS13590	COG0512	Glutamine amidotransferase of anthranilate synthase
FIV04_RS13595	COG2356	endonuclease I
FIV04_RS13615	COG0180	Tryptophanyl-tRNA synthetase
FIV04_RS13625	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FIV04_RS13630	COG0338	D12 class N6 adenine-specific DNA methyltransferase
FIV04_RS13640	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FIV04_RS13675	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FIV04_RS13685	COG0678	peroxiredoxin activity
FIV04_RS13685	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FIV04_RS13690	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FIV04_RS13695	COG0251	oxidation-reduction process
FIV04_RS13705	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FIV04_RS13705	COG0165	Argininosuccinate lyase
FIV04_RS13720	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FIV04_RS13725	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FIV04_RS13730	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FIV04_RS13740	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FIV04_RS13745	COG0527	aspartate kinase activity
FIV04_RS13745	COG0460	homoserine dehydrogenase
FIV04_RS13750	COG0626	cystathionine gamma-synthase activity
FIV04_RS13755	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
FIV04_RS13760	COG0281	malic enzyme
FIV04_RS13765	COG0254	rRNA binding
FIV04_RS13770	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FIV04_RS13775	COG1609	Transcriptional regulator
FIV04_RS13785	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FIV04_RS13790	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FIV04_RS13795	COG1575	Belongs to the MenA family. Type 1 subfamily
FIV04_RS13800	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FIV04_RS13805	COG3074	FtsZ-dependent cytokinesis
FIV04_RS13810	COG1494	fructose-1,6-bisphosphatase
FIV04_RS13835	COG0149	triose-phosphate isomerase activity
FIV04_RS13845	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FIV04_RS13855	COG0745	RESPONSE REGULATOR receiver
FIV04_RS13860	COG2205	protein histidine kinase activity
FIV04_RS13865	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FIV04_RS13870	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FIV04_RS13880	COG1027	Aspartate ammonia-lyase
FIV04_RS13885	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FIV04_RS13890	COG4232	protein-disulfide reductase activity
FIV04_RS13900	COG2095	MarC family integral membrane protein
FIV04_RS13910	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FIV04_RS13925	COG0784	Response regulator, receiver
FIV04_RS13925	COG2198	Histidine kinase
FIV04_RS13925	COG2205	protein histidine kinase activity
FIV04_RS13930	COG2814	Major facilitator Superfamily
FIV04_RS13945	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FIV04_RS13950	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FIV04_RS13955	COG0511	ligase activity, forming carbon-carbon bonds
FIV04_RS13960	COG0439	Biotin carboxylase
FIV04_RS13970	COG2264	protein methyltransferase activity
FIV04_RS13975	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FIV04_RS13980	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FIV04_RS13995	COG0138	bifunctional purine biosynthesis protein purh
FIV04_RS14000	COG0151	Belongs to the GarS family
FIV04_RS14020	COG3068	Protein conserved in bacteria
FIV04_RS14040	COG2816	NAD+ diphosphatase activity
FIV04_RS14045	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
FIV04_RS14055	COG0085	RNA polymerase activity
FIV04_RS14065	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FIV04_RS14070	COG0081	regulation of translation
FIV04_RS14080	COG0250	Participates in transcription elongation, termination and antitermination
FIV04_RS14085	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FIV04_RS14090	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FIV04_RS14115	COG1072	(Pantothenic acid kinase))
FIV04_RS14125	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FIV04_RS14135	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FIV04_RS14220	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FIV04_RS14225	COG0137	argininosuccinate synthase activity
FIV04_RS14230	COG4206	TonB-dependent receptor
FIV04_RS14235	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FIV04_RS14250	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FIV04_RS14255	COG0534	Mate efflux family protein
FIV04_RS14265	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FIV04_RS14270	COG2937	Belongs to the GPAT DAPAT family
FIV04_RS14275	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FIV04_RS14280	COG3161	chorismate lyase activity
FIV04_RS14285	COG1580	Controls the rotational direction of flagella during chemotaxis
FIV04_RS14295	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FIV04_RS14305	COG2177	Part of the ABC transporter FtsEX involved in
FIV04_RS14310	COG2884	Cell division ATP-binding protein ftsE
FIV04_RS14315	COG0552	protein localization to endoplasmic reticulum
FIV04_RS14320	COG0742	ribosomal rna small subunit methyltransferase
FIV04_RS14330	COG2095	MarC family integral membrane protein
FIV04_RS14375	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FIV04_RS14380	COG0640	Transcriptional regulator
FIV04_RS14385	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FIV04_RS14390	COG1280	lysine exporter protein (LysE YggA)
FIV04_RS14400	COG0561	phosphatase activity
FIV04_RS14415	COG3148	PFAM DTW domain containing protein
FIV04_RS14420	COG3287	FIST C domain
FIV04_RS14420	COG2200	EAL domain
FIV04_RS14420	COG2199	diguanylate cyclase activity
FIV04_RS14425	COG3287	FIST C domain
FIV04_RS14425	COG2200	EAL domain
FIV04_RS14425	COG2199	diguanylate cyclase activity
FIV04_RS14430	COG1011	Hydrolase
FIV04_RS14435	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FIV04_RS14445	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FIV04_RS14450	COG0019	diaminopimelate decarboxylase activity
FIV04_RS14460	COG1965	Belongs to the frataxin family
FIV04_RS14470	COG0181	hydroxymethylbilane synthase activity
FIV04_RS14475	COG1587	Uroporphyrinogen-III synthase
FIV04_RS14480	COG2959	enzyme of heme biosynthesis
FIV04_RS14485	COG3071	HemY protein
FIV04_RS14550	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FIV04_RS14565	COG3118	belongs to the thioredoxin family
FIV04_RS14570	COG0513	Belongs to the DEAD box helicase family
FIV04_RS14575	COG0248	Ppx GppA phosphatase
FIV04_RS14580	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FIV04_RS14590	COG0514	ATP-dependent DNA helicase (RecQ)
FIV04_RS14595	COG2962	Rard protein
FIV04_RS14605	COG1280	lysine exporter protein (LysE YggA)
FIV04_RS14610	COG0405	Gamma-glutamyltransferase
FIV04_RS14620	COG0210	DNA helicase
FIV04_RS14630	COG3220	belongs to the UPF0276 family
FIV04_RS14660	COG0006	proline dipeptidase activity
FIV04_RS14660	COG0006	proline dipeptidase activity
FIV04_RS14680	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FIV04_RS14695	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FIV04_RS14700	COG2132	Multicopper oxidase
FIV04_RS14755	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FIV04_RS14765	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FIV04_RS14770	COG0408	coproporphyrinogen oxidase activity
FIV04_RS14775	COG0009	L-threonylcarbamoyladenylate synthase
FIV04_RS14780	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FIV04_RS14785	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FIV04_RS14790	COG0551	DNA topoisomerase type I activity
FIV04_RS14795	COG2922	Belongs to the Smg family
FIV04_RS14800	COG0758	DNA mediated transformation
FIV04_RS14810	COG0242	peptide deformylase activity
FIV04_RS14820	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FIV04_RS14820	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FIV04_RS14825	COG0569	domain protein
FIV04_RS14830	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FIV04_RS14840	COG1272	protein, Hemolysin III
FIV04_RS14845	COG4326	sporulation control protein
FIV04_RS14850	COG3084	Protein conserved in bacteria
FIV04_RS14860	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FIV04_RS14865	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FIV04_RS14915	COG0606	chelatase, subunit chli
FIV04_RS14925	COG3978	acetolactate synthase activity
FIV04_RS14930	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FIV04_RS14945	COG0583	DNA-binding transcription factor activity
FIV04_RS14950	COG2814	Major facilitator Superfamily
FIV04_RS14955	COG3706	GGDEF domain
FIV04_RS14965	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FIV04_RS14970	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FIV04_RS14975	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FIV04_RS14980	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FIV04_RS14985	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FIV04_RS14990	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FIV04_RS15005	COG3312	ion transport
FIV04_RS15010	COG1475	DNA binding
FIV04_RS15015	COG1192	Involved in chromosome partitioning
FIV04_RS15020	COG0357	Ribosomal RNA small subunit methyltransferase G
FIV04_RS15025	COG0445	tRNA wobble uridine modification
FIV04_RS15030	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FIV04_RS15040	COG0706	membrane insertase activity
FIV04_RS15045	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FIV04_RS15055	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FIV04_RS15060	COG1126	abc transporter atp-binding protein
FIV04_RS15085	COG3712	iron ion homeostasis
FIV04_RS15125	COG0848	biopolymer transport protein
FIV04_RS15135	COG0277	FAD linked oxidase domain protein
FIV04_RS15140	COG0583	DNA-binding transcription factor activity
FIV04_RS15175	COG1294	oxidase, subunit
FIV04_RS15180	COG1271	oxidase subunit
FIV04_RS15185	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FIV04_RS15190	COG0840	transmembrane signaling receptor activity
FIV04_RS15210	COG2425	protein containing a von Willebrand factor type A (vWA) domain
FIV04_RS15220	COG0494	nUDIX hydrolase
FIV04_RS15225	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
FIV04_RS15230	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FIV04_RS15235	COG3706	GGDEF domain
FIV04_RS15240	COG0456	acetyltransferase
FIV04_RS15240	COG1214	PFAM Peptidase M22, glycoprotease
FIV04_RS15265	COG1929	Belongs to the glycerate kinase type-1 family
FIV04_RS15270	COG0383	alpha-mannosidase activity
FIV04_RS15275	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FIV04_RS15275	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FIV04_RS15275	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FIV04_RS15280	COG2188	Transcriptional regulator
FIV04_RS15290	COG0840	transmembrane signaling receptor activity
FIV04_RS15295	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FIV04_RS15300	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FIV04_RS15305	COG2067	long-chain fatty acid transport protein
FIV04_RS15310	COG2267	carboxylic ester hydrolase activity
FIV04_RS15315	COG0745	RESPONSE REGULATOR receiver
FIV04_RS15325	COG3069	C4-dicarboxylate transmembrane transporter activity
FIV04_RS15330	COG2197	response regulator
FIV04_RS15335	COG3850	Histidine kinase
FIV04_RS15350	COG0243	molybdopterin cofactor binding
FIV04_RS15380	COG0183	Belongs to the thiolase family
FIV04_RS15420	COG5002	protein histidine kinase activity
FIV04_RS15425	COG0745	RESPONSE REGULATOR receiver
FIV04_RS15455	COG1280	lysine exporter protein (LysE YggA)
FIV04_RS15460	COG0513	Belongs to the DEAD box helicase family
FIV04_RS15465	COG0523	cobalamin synthesis protein
FIV04_RS15470	COG0038	chloride channel
FIV04_RS15480	COG2199	diguanylate cyclase activity
FIV04_RS15480	COG2200	EAL domain
FIV04_RS15480	COG2202	Pas domain
FIV04_RS15485	COG1017	nitric oxide dioxygenase activity
FIV04_RS15485	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FIV04_RS15490	COG3604	Transcriptional regulator
FIV04_RS15500	COG2885	chlorophyll binding
FIV04_RS15510	COG0545	Peptidyl-prolyl cis-trans isomerase
FIV04_RS15515	COG1309	transcriptional regulator
FIV04_RS15520	COG2130	NADP-dependent
FIV04_RS15530	COG0564	pseudouridine synthase activity
FIV04_RS15540	COG0583	DNA-binding transcription factor activity
FIV04_RS15545	COG1686	Belongs to the peptidase S11 family
FIV04_RS15575	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FIV04_RS15615	COG2207	Transcriptional regulator
FIV04_RS15620	COG1979	alcohol dehydrogenase
FIV04_RS15625	COG1126	abc transporter atp-binding protein
FIV04_RS15630	COG0765	amino acid transport
FIV04_RS15635	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FIV04_RS15640	COG0765	amino acid transport
FIV04_RS15645	COG4206	TonB-dependent receptor
FIV04_RS15650	COG4977	sequence-specific DNA binding
FIV04_RS15660	COG1280	lysine exporter protein (LysE YggA)
FIV04_RS15745	COG1902	pentaerythritol trinitrate reductase activity
FIV04_RS15765	COG1024	Enoyl-CoA hydratase
FIV04_RS15770	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FIV04_RS15795	COG1120	ATPase activity
FIV04_RS15805	COG2133	pyrroloquinoline quinone binding
FIV04_RS15815	COG1278	Cold shock
FIV04_RS15820	COG4681	YaeQ
FIV04_RS15830	COG0302	gtp cyclohydrolase
FIV04_RS15860	COG2897	thiosulfate sulfurtransferase activity
FIV04_RS15880	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FIV04_RS15885	COG1522	sequence-specific DNA binding
FIV04_RS15895	COG0840	transmembrane signaling receptor activity
FIV04_RS15900	COG1560	Kdo2-lipid A biosynthetic process
FIV04_RS15905	COG2814	Major facilitator Superfamily
FIV04_RS15910	COG0583	DNA-binding transcription factor activity
FIV04_RS15915	COG0784	Response regulator, receiver
FIV04_RS15915	COG5002	protein histidine kinase activity
FIV04_RS15920	COG3437	response regulator, receiver
FIV04_RS15925	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FIV04_RS15940	COG2186	Transcriptional regulator
FIV04_RS15945	COG2186	Transcriptional regulator
FIV04_RS15970	COG4604	ABC transporter, ATP-binding protein
FIV04_RS15975	COG4605	iron ion homeostasis
FIV04_RS15980	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FIV04_RS15985	COG4607	ABC-type enterochelin transport system periplasmic component
FIV04_RS16010	COG1917	Cupin 2, conserved barrel domain protein
FIV04_RS16015	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FIV04_RS16020	COG0800	Aldolase
FIV04_RS16045	COG0628	permease
FIV04_RS16055	COG1566	PFAM secretion protein HlyD family protein
FIV04_RS16080	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FIV04_RS16120	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FIV04_RS16125	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FIV04_RS16130	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FIV04_RS16135	COG1116	anion transmembrane transporter activity
FIV04_RS16140	COG0351	phosphomethylpyrimidine kinase
FIV04_RS16155	COG1253	flavin adenine dinucleotide binding
FIV04_RS16170	COG3710	Transcriptional regulator
FIV04_RS16200	COG2226	methyltransferase
FIV04_RS16225	COG0348	domain, Protein
FIV04_RS16230	COG0437	4 iron, 4 sulfur cluster binding
FIV04_RS16290	COG0745	RESPONSE REGULATOR receiver
FIV04_RS16295	COG2205	protein histidine kinase activity
FIV04_RS16300	COG0702	epimerase
FIV04_RS16350	COG0516	GMP reductase activity
FIV04_RS16380	COG0534	Mate efflux family protein
FIV04_RS16385	COG0583	DNA-binding transcription factor activity
FIV04_RS16390	COG0840	transmembrane signaling receptor activity
FIV04_RS16395	COG0840	transmembrane signaling receptor activity
FIV04_RS16400	COG0673	inositol 2-dehydrogenase activity
FIV04_RS16520	COG2814	Major facilitator Superfamily
FIV04_RS16530	COG3437	response regulator, receiver
FIV04_RS16530	COG0784	Response regulator, receiver
FIV04_RS16535	COG0784	Response regulator, receiver
FIV04_RS16535	COG4191	Histidine kinase
FIV04_RS16555	COG3135	benzoate transporter
FIV04_RS16560	COG1396	sequence-specific DNA binding
FIV04_RS16565	COG1752	Esterase of the alpha-beta hydrolase superfamily
FIV04_RS16570	COG2356	endonuclease I
FIV04_RS16605	COG1028	Short-chain dehydrogenase reductase Sdr
FIV04_RS16620	COG3706	GGDEF domain
FIV04_RS16635	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FIV04_RS16645	COG0513	Belongs to the DEAD box helicase family
FIV04_RS16650	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
FIV04_RS16700	COG2195	Cleaves the N-terminal amino acid of tripeptides
FIV04_RS16705	COG0667	Aldo Keto reductase
FIV04_RS16710	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FIV04_RS16715	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FIV04_RS16720	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
FIV04_RS16725	COG0778	Nitroreductase
FIV04_RS16730	COG0513	Belongs to the DEAD box helicase family
FIV04_RS16735	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FIV04_RS16740	COG2176	DNA-directed DNA polymerase activity
FIV04_RS16755	COG0513	Belongs to the DEAD box helicase family
FIV04_RS16765	COG4989	oxidoreductase activity
FIV04_RS16795	COG2197	response regulator
FIV04_RS16805	COG0668	transmembrane transport
FIV04_RS16820	COG4232	protein-disulfide reductase activity
FIV04_RS16845	COG0697	spore germination
FIV04_RS16860	COG2814	Major facilitator Superfamily
FIV04_RS16865	COG0583	DNA-binding transcription factor activity
FIV04_RS16870	COG5001	Diguanylate cyclase
FIV04_RS16875	COG0739	heme binding
FIV04_RS16900	COG3314	Sporulation integral membrane protein YlbJ
FIV04_RS16910	COG0366	Alpha amylase catalytic
FIV04_RS16915	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FIV04_RS16920	COG0835	chemotaxis
FIV04_RS16920	COG0784	Response regulator, receiver
FIV04_RS16930	COG0748	coenzyme F420 binding
FIV04_RS16935	COG3721	Heme iron utilization protein
FIV04_RS16950	COG0811	peptide transport
FIV04_RS16955	COG0848	biopolymer transport protein
FIV04_RS16965	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FIV04_RS16970	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FIV04_RS17015	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FIV04_RS17020	COG0633	Ferredoxin
FIV04_RS17020	COG3217	Mosc domain protein beta barrel domain protein
FIV04_RS17025	COG0401	homolog of Blt101
FIV04_RS17030	COG0418	dihydroorotase activity
FIV04_RS17035	COG3706	GGDEF domain
FIV04_RS17055	COG0583	DNA-binding transcription factor activity
FIV04_RS17070	COG0312	modulator of DNA gyrase
FIV04_RS17075	COG0312	modulator of DNA gyrase
FIV04_RS17100	COG1136	(ABC) transporter
FIV04_RS17105	COG0577	efflux transmembrane transporter activity
FIV04_RS17125	COG2814	Major facilitator Superfamily
FIV04_RS17135	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FIV04_RS17160	COG3833	ABC-type maltose transport systems, permease component
FIV04_RS17165	COG1175	transmembrane transport
FIV04_RS17175	COG3842	ATPase activity
FIV04_RS17190	COG0714	Associated with various cellular activities
FIV04_RS17210	COG2304	oxidoreductase activity
FIV04_RS17220	COG3706	GGDEF domain
FIV04_RS17225	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FIV04_RS17230	COG0581	inorganic phosphate transmembrane transporter activity
FIV04_RS17235	COG0573	inorganic phosphate transmembrane transporter activity
FIV04_RS17245	COG0840	transmembrane signaling receptor activity
FIV04_RS17265	COG4771	TonB-dependent receptor
FIV04_RS17270	COG1770	oligopeptidase
FIV04_RS17275	COG5380	lipid catabolic process
FIV04_RS17280	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
FIV04_RS17285	COG3240	lipase activity
FIV04_RS17290	COG0513	Belongs to the DEAD box helicase family
FIV04_RS17300	COG1388	LysM domain
FIV04_RS17300	COG1376	ErfK ybiS ycfS ynhG family protein
FIV04_RS17305	COG0813	purine-nucleoside phosphorylase activity
FIV04_RS17335	COG1566	PFAM secretion protein HlyD family protein
FIV04_RS17340	COG4720	Psort location CytoplasmicMembrane, score
FIV04_RS17345	COG1122	ATPase activity
FIV04_RS17360	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FIV04_RS17365	COG1640	4-alpha-glucanotransferase
FIV04_RS17370	COG0058	SHG alpha-glucan phosphorylase activity
FIV04_RS17390	COG1999	signal sequence binding
FIV04_RS17400	COG1162	GTPase activity
FIV04_RS17405	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
FIV04_RS17450	COG0366	Alpha amylase catalytic
FIV04_RS17490	COG2384	SAM-dependent methyltransferase
FIV04_RS17495	COG0204	Acyl-transferase
FIV04_RS17505	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FIV04_RS17525	COG3615	Tellurite resistance protein tehB
FIV04_RS17530	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FIV04_RS17535	COG4667	esterase of the alpha-beta hydrolase superfamily
FIV04_RS17540	COG1929	Belongs to the glycerate kinase type-1 family
FIV04_RS17550	COG3623	hexulose-6-phosphate isomerase
FIV04_RS17555	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
FIV04_RS17560	COG0561	phosphatase activity
FIV04_RS17605	COG0673	inositol 2-dehydrogenase activity
FIV04_RS17615	COG0583	DNA-binding transcription factor activity
FIV04_RS17640	COG0561	phosphatase activity
FIV04_RS17660	COG0798	PFAM Bile acid sodium symporter
FIV04_RS17665	COG0583	DNA-binding transcription factor activity
FIV04_RS17675	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FIV04_RS17680	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FIV04_RS17685	COG1349	DNA-binding transcription factor activity
FIV04_RS17690	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FIV04_RS17695	COG1028	Short-chain dehydrogenase reductase Sdr
FIV04_RS17700	COG0583	DNA-binding transcription factor activity
FIV04_RS17715	COG0300	oxidoreductase activity
FIV04_RS17735	COG1120	ATPase activity
FIV04_RS17740	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FIV04_RS17760	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FIV04_RS17765	COG0488	(ABC) transporter
FIV04_RS17770	COG0667	Aldo Keto reductase
FIV04_RS17780	COG1917	Cupin 2, conserved barrel domain protein
FIV04_RS17780	COG2207	Transcriptional regulator
FIV04_RS17790	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FIV04_RS17810	COG1940	carbohydrate kinase activity
FIV04_RS17820	COG3833	ABC-type maltose transport systems, permease component
FIV04_RS17825	COG1175	transmembrane transport
FIV04_RS17830	COG2182	Extracellular solute-binding protein
FIV04_RS17840	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FIV04_RS17855	COG3842	ATPase activity
FIV04_RS17865	COG0583	DNA-binding transcription factor activity
FIV04_RS17870	COG2814	Major facilitator Superfamily
FIV04_RS17875	COG0110	maltose O-acetyltransferase activity
FIV04_RS17885	COG1609	Transcriptional regulator
FIV04_RS17890	COG2723	6-phospho-beta-galactosidase activity
FIV04_RS17905	COG0346	lactoylglutathione lyase activity
FIV04_RS17915	COG0534	Mate efflux family protein
FIV04_RS17925	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FIV04_RS17925	COG0646	methionine synthase
FIV04_RS17930	COG0735	belongs to the Fur family
FIV04_RS17945	COG0604	alcohol dehydrogenase
FIV04_RS17945	COG3321	synthase
FIV04_RS17945	COG1028	Short-chain dehydrogenase reductase Sdr
FIV04_RS17955	COG2814	Major facilitator Superfamily
FIV04_RS17960	COG2207	Transcriptional regulator
FIV04_RS17975	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FIV04_RS17985	COG2165	general secretion pathway protein
FIV04_RS18000	COG2188	Transcriptional regulator
FIV04_RS18015	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FIV04_RS18015	COG1263	PTS System
FIV04_RS18020	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FIV04_RS18025	COG0800	Aldolase
FIV04_RS18030	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FIV04_RS18040	COG1846	Transcriptional regulator
FIV04_RS18045	COG1132	(ABC) transporter
FIV04_RS18050	COG1132	(ABC) transporter
FIV04_RS18055	COG4771	TonB-dependent receptor
FIV04_RS18070	COG4175	Glycine betaine
FIV04_RS18090	COG1012	belongs to the aldehyde dehydrogenase family
FIV04_RS18095	COG1309	transcriptional regulator
FIV04_RS18115	COG3842	ATPase activity
FIV04_RS18160	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FIV04_RS18165	COG1012	belongs to the aldehyde dehydrogenase family
FIV04_RS18170	COG2957	Belongs to the agmatine deiminase family
FIV04_RS18180	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FIV04_RS18185	COG1012	belongs to the aldehyde dehydrogenase family
FIV04_RS18190	COG1396	sequence-specific DNA binding
FIV04_RS18190	COG1917	Cupin 2, conserved barrel domain protein
FIV04_RS18195	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FIV04_RS18205	COG0174	glutamine synthetase
FIV04_RS18210	COG1757	Na H antiporter
FIV04_RS18225	COG0583	DNA-binding transcription factor activity
FIV04_RS18240	COG1132	(ABC) transporter
FIV04_RS18270	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FIV04_RS18305	COG0259	pyridoxamine-phosphate oxidase activity
FIV04_RS18345	COG1444	tRNA N-acetyltransferase activity
FIV04_RS18370	COG4608	Belongs to the ABC transporter superfamily
FIV04_RS18375	COG0444	Belongs to the ABC transporter superfamily
FIV04_RS18385	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FIV04_RS18385	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
FIV04_RS18405	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
FIV04_RS18415	COG0625	glutathione transferase activity
FIV04_RS18420	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FIV04_RS18425	COG3186	Phenylalanine-4-hydroxylase
FIV04_RS18440	COG0217	transcriptional regulatory protein
FIV04_RS18455	COG2084	Dehydrogenase
FIV04_RS18480	COG1136	(ABC) transporter
FIV04_RS18480	COG0577	efflux transmembrane transporter activity
FIV04_RS18505	COG3279	Response regulator of the LytR AlgR family
FIV04_RS18510	COG0612	Peptidase, M16
FIV04_RS18520	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FIV04_RS18525	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FIV04_RS18535	COG1902	pentaerythritol trinitrate reductase activity
FIV04_RS18560	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FIV04_RS18565	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FIV04_RS18570	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FIV04_RS18595	COG1881	PFAM PEBP family protein
FIV04_RS18600	COG2207	Transcriptional regulator
FIV04_RS18605	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FIV04_RS18610	COG0667	Aldo Keto reductase
FIV04_RS18625	COG0583	DNA-binding transcription factor activity
FIV04_RS18630	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FIV04_RS18645	COG0679	Auxin Efflux Carrier
FIV04_RS18665	COG0450	alkyl hydroperoxide reductase
FIV04_RS18680	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FIV04_RS18690	COG1233	COG1233 Phytoene dehydrogenase and related
FIV04_RS18705	COG0415	Belongs to the DNA photolyase family
FIV04_RS18715	COG3806	Anti-sigma factor
FIV04_RS18720	COG1595	DNA-templated transcription, initiation
FIV04_RS18730	COG1942	4-Oxalocrotonate Tautomerase
FIV04_RS18745	COG0786	glutamate:sodium symporter activity
FIV04_RS18770	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FIV04_RS18770	COG2213	PTS system mannitol-specific
FIV04_RS18775	COG0246	Mannitol dehydrogenase
FIV04_RS18780	COG3722	fumarate hydratase activity
FIV04_RS18785	COG0363	glucosamine-6-phosphate deaminase activity
FIV04_RS18805	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FIV04_RS18820	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FIV04_RS18825	COG3366	ferrous iron transmembrane transporter activity
FIV04_RS18830	COG0700	Nucleoside recognition
FIV04_RS18835	COG3788	relative of glutathione S-transferase, MAPEG superfamily
FIV04_RS18855	COG0671	phosphoesterase, PA-phosphatase related
FIV04_RS18890	COG0596	Alpha beta hydrolase
FIV04_RS18905	COG3123	guanosine phosphorylase activity
FIV04_RS18910	COG1741	Belongs to the pirin family
FIV04_RS18920	COG5001	Diguanylate cyclase
FIV04_RS18940	COG1054	Belongs to the UPF0176 family
FIV04_RS18950	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FIV04_RS18955	COG2207	Transcriptional regulator
FIV04_RS18955	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FIV04_RS18965	COG1304	FMN binding
FIV04_RS18970	COG1620	l-lactate permease
FIV04_RS18975	COG0583	DNA-binding transcription factor activity
FIV04_RS18980	COG1505	serine-type exopeptidase activity
FIV04_RS18985	COG4172	Belongs to the ABC transporter superfamily
FIV04_RS18995	COG1067	ATP-dependent peptidase activity
FIV04_RS19050	COG0583	DNA-binding transcription factor activity
FIV04_RS19060	COG1846	Transcriptional regulator
FIV04_RS19070	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FIV04_RS19075	COG3960	tartronate-semialdehyde synthase activity
FIV04_RS19080	COG3622	Belongs to the hyi family
FIV04_RS19085	COG2084	Dehydrogenase
FIV04_RS19100	COG0402	S-adenosylhomocysteine deaminase activity
FIV04_RS19125	COG2252	PERMEase
FIV04_RS19145	COG4266	Belongs to the allantoicase family
FIV04_RS19150	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
FIV04_RS19170	COG1228	amidohydrolase
FIV04_RS19180	COG0402	S-adenosylhomocysteine deaminase activity
FIV04_RS19190	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FIV04_RS19200	COG2186	Transcriptional regulator
FIV04_RS19210	COG1418	mRNA catabolic process
FIV04_RS19215	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FIV04_RS19220	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FIV04_RS19240	COG0625	glutathione transferase activity
FIV04_RS19245	COG0583	DNA-binding transcription factor activity
FIV04_RS19250	COG3284	Transcriptional regulator
FIV04_RS19255	COG1012	belongs to the aldehyde dehydrogenase family
FIV04_RS19270	COG1288	antiporter activity
FIV04_RS19295	COG0167	dihydroorotate dehydrogenase activity
FIV04_RS19315	COG0745	RESPONSE REGULATOR receiver
FIV04_RS19320	COG2205	protein histidine kinase activity
FIV04_RS19325	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FIV04_RS19330	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FIV04_RS19360	COG0745	RESPONSE REGULATOR receiver
FIV04_RS19365	COG2205	protein histidine kinase activity
FIV04_RS19385	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FIV04_RS19385	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FIV04_RS19390	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FIV04_RS19410	COG0251	oxidation-reduction process
FIV04_RS19445	COG0583	DNA-binding transcription factor activity
FIV04_RS19470	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FIV04_RS19475	COG3842	ATPase activity
FIV04_RS19480	COG0765	amino acid transport
FIV04_RS19490	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FIV04_RS19515	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FIV04_RS19515	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FIV04_RS19515	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FIV04_RS19520	COG2207	Transcriptional regulator
FIV04_RS19530	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FIV04_RS19535	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FIV04_RS19545	COG0840	transmembrane signaling receptor activity
FIV04_RS19550	COG2188	Transcriptional regulator
FIV04_RS19555	COG2223	nitrite transmembrane transporter activity
FIV04_RS19560	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FIV04_RS19565	COG1397	ADP-ribosylglycohydrolase
FIV04_RS19570	COG2211	Major facilitator Superfamily
FIV04_RS19585	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FIV04_RS19600	COG0840	transmembrane signaling receptor activity
FIV04_RS19610	COG0583	DNA-binding transcription factor activity
FIV04_RS19645	COG4191	Histidine kinase
FIV04_RS19650	COG2204	response regulator
FIV04_RS19665	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FIV04_RS19670	COG3639	organic phosphonate transmembrane transporter activity
FIV04_RS19675	COG3639	organic phosphonate transmembrane transporter activity
FIV04_RS19695	COG1288	antiporter activity
FIV04_RS19700	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FIV04_RS19705	COG3047	cAMP biosynthetic process
FIV04_RS19715	COG2358	TRAP transporter, solute receptor (TAXI family
FIV04_RS19725	COG4251	negative regulation of phosphorylation
FIV04_RS19725	COG5001	Diguanylate cyclase
FIV04_RS19725	COG3706	GGDEF domain
FIV04_RS19725	COG2203	Gaf domain
FIV04_RS19730	COG4221	oxidoreductase activity
FIV04_RS19740	COG1733	regulation of RNA biosynthetic process
FIV04_RS19745	COG1028	Short-chain dehydrogenase reductase Sdr
FIV04_RS19755	COG2910	NAD(P)H-binding
FIV04_RS19760	COG0583	DNA-binding transcription factor activity
FIV04_RS19770	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FIV04_RS19795	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FIV04_RS19820	COG1901	pseudouridine methyltransferase
FIV04_RS19875	COG3321	synthase
FIV04_RS19875	COG0604	alcohol dehydrogenase
FIV04_RS19890	COG0446	pyridine nucleotide-disulphide oxidoreductase
FIV04_RS19900	COG0251	oxidation-reduction process
FIV04_RS19905	COG2964	Protein conserved in bacteria
FIV04_RS19910	COG0534	Mate efflux family protein
FIV04_RS19935	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FIV04_RS19980	COG2999	glutathione oxidoreductase activity
FIV04_RS19990	COG0673	inositol 2-dehydrogenase activity
FIV04_RS20005	COG0584	glycerophosphoryl diester phosphodiesterase
FIV04_RS20020	COG0189	ligase activity
FIV04_RS20020	COG4067	protein conserved in archaea
FIV04_RS20025	COG0189	ligase activity
FIV04_RS20035	COG0840	transmembrane signaling receptor activity
FIV04_RS20055	COG3708	Transcriptional regulator
FIV04_RS20055	COG2207	Transcriptional regulator
FIV04_RS20070	COG0564	pseudouridine synthase activity
FIV04_RS20100	COG1131	(ABC) transporter
FIV04_RS20115	COG2200	EAL domain
FIV04_RS20125	COG5001	Diguanylate cyclase
FIV04_RS20135	COG0745	RESPONSE REGULATOR receiver
FIV04_RS20140	COG2205	protein histidine kinase activity
FIV04_RS20145	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FIV04_RS20150	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FIV04_RS20160	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FIV04_RS20185	COG0513	Belongs to the DEAD box helicase family
FIV04_RS20200	COG3706	GGDEF domain
FIV04_RS20205	COG1278	Cold shock
FIV04_RS20210	COG0402	S-adenosylhomocysteine deaminase activity
FIV04_RS20215	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FIV04_RS20220	COG1566	PFAM secretion protein HlyD family protein
FIV04_RS20245	COG0531	amino acid
FIV04_RS20275	COG1151	hydroxylamine reductase activity
FIV04_RS20280	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FIV04_RS20305	COG2926	Belongs to the UPF0265 family
FIV04_RS20315	COG3132	Protein of unknown function, DUF480
FIV04_RS20320	COG2827	Endonuclease containing a URI domain
FIV04_RS20330	COG0784	Response regulator, receiver
FIV04_RS20330	COG2205	protein histidine kinase activity
FIV04_RS20350	COG0443	Heat shock 70 kDa protein
FIV04_RS20360	COG0179	Fumarylacetoacetate (FAA) hydrolase
FIV04_RS20365	COG1280	lysine exporter protein (LysE YggA)
FIV04_RS20370	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FIV04_RS20375	COG1565	acr, cog1565
FIV04_RS20375	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FIV04_RS20390	COG1845	cytochrome c oxidase, subunit III
FIV04_RS20415	COG0109	protoheme IX farnesyltransferase activity
FIV04_RS20430	COG3530	Putative quorum-sensing-regulated virulence factor
FIV04_RS20435	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FIV04_RS20445	COG0668	transmembrane transport
FIV04_RS20450	COG0569	domain protein
FIV04_RS20455	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FIV04_RS20460	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FIV04_RS20460	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FIV04_RS20465	COG1765	OsmC-like protein
FIV04_RS20480	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FIV04_RS20485	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FIV04_RS20490	COG1840	ABC-type Fe3 transport system, periplasmic component
FIV04_RS20495	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FIV04_RS20500	COG3842	ATPase activity
FIV04_RS20510	COG2188	Transcriptional regulator
FIV04_RS20520	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FIV04_RS20530	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FIV04_RS20530	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FIV04_RS20535	COG3265	gluconokinase activity
FIV04_RS20540	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FIV04_RS20545	COG1609	Transcriptional regulator
FIV04_RS20555	COG3104	oligopeptide transport
FIV04_RS20560	COG1760	l-serine dehydratase
FIV04_RS20585	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FIV04_RS20600	COG0583	DNA-binding transcription factor activity
FIV04_RS20605	COG2249	NAD(P)H dehydrogenase (quinone) activity
FIV04_RS20615	COG1609	Transcriptional regulator
FIV04_RS20620	COG1263	PTS System
FIV04_RS20620	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FIV04_RS20625	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FIV04_RS20630	COG1621	beta-fructofuranosidase activity
FIV04_RS20640	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FIV04_RS20650	COG0523	cobalamin synthesis protein
FIV04_RS20655	COG2988	succinylglutamate desuccinylase activity
FIV04_RS20660	COG1132	(ABC) transporter
FIV04_RS20665	COG1132	(ABC) transporter
FIV04_RS20675	COG3119	arylsulfatase activity
FIV04_RS20695	COG0739	heme binding
FIV04_RS20700	COG0393	Putative heavy-metal-binding
FIV04_RS20720	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FIV04_RS20740	COG0346	lactoylglutathione lyase activity
FIV04_RS20750	COG2211	Major facilitator Superfamily
FIV04_RS20765	COG0156	8-amino-7-oxononanoate synthase activity
FIV04_RS20770	COG1063	alcohol dehydrogenase
FIV04_RS20815	COG1454	alcohol dehydrogenase
FIV04_RS20820	COG1011	Hydrolase
FIV04_RS20825	COG4251	negative regulation of phosphorylation
FIV04_RS20825	COG3706	GGDEF domain
FIV04_RS20825	COG2203	Gaf domain
FIV04_RS20825	COG5001	Diguanylate cyclase
FIV04_RS20845	COG2264	protein methyltransferase activity
FIV04_RS20850	COG1328	CTP reductase activity
FIV04_RS20855	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FIV04_RS20870	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FIV04_RS20880	COG3547	Transposase (IS116 IS110 IS902 family)
FIV04_RS20915	COG0583	DNA-binding transcription factor activity
FIV04_RS20930	COG1289	transmembrane transporter activity
FIV04_RS20935	COG0210	DNA helicase
FIV04_RS20945	COG1803	Methylglyoxal synthase
FIV04_RS20950	COG1879	ABC-type sugar transport system periplasmic component
FIV04_RS20955	COG2198	Histidine kinase
FIV04_RS20955	COG2205	protein histidine kinase activity
FIV04_RS20955	COG0784	Response regulator, receiver
FIV04_RS20965	COG1629	transport
FIV04_RS21000	COG0625	glutathione transferase activity
FIV04_RS21010	COG2205	protein histidine kinase activity
FIV04_RS21015	COG0745	RESPONSE REGULATOR receiver
FIV04_RS21050	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FIV04_RS21050	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FIV04_RS21050	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
FIV04_RS21055	COG1105	Belongs to the carbohydrate kinase PfkB family
FIV04_RS21060	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FIV04_RS21060	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FIV04_RS21065	COG1609	Transcriptional regulator
FIV04_RS21070	COG0515	serine threonine protein kinase
FIV04_RS21070	COG2815	serine threonine protein kinase
FIV04_RS21075	COG2223	nitrite transmembrane transporter activity
FIV04_RS21085	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FIV04_RS21085	COG2146	nitrite reductase [NAD(P)H] activity
FIV04_RS21090	COG0243	molybdopterin cofactor binding
FIV04_RS21190	COG0642	Histidine kinase
FIV04_RS21195	COG0745	RESPONSE REGULATOR receiver
FIV04_RS21200	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FIV04_RS21210	COG1538	Outer membrane efflux protein
FIV04_RS21225	COG0789	Transcriptional regulator
FIV04_RS21230	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FIV04_RS21235	COG1247	-acetyltransferase
FIV04_RS21265	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FIV04_RS21275	COG0583	DNA-binding transcription factor activity
FIV04_RS21280	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FIV04_RS21300	COG2205	protein histidine kinase activity
FIV04_RS21300	COG0784	Response regulator, receiver
FIV04_RS21305	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FIV04_RS21310	COG0840	transmembrane signaling receptor activity
FIV04_RS21315	COG1609	Transcriptional regulator
FIV04_RS21320	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FIV04_RS21325	COG1879	ABC-type sugar transport system periplasmic component
FIV04_RS21330	COG1172	Belongs to the binding-protein-dependent transport system permease family
FIV04_RS21335	COG1129	ABC transporter
FIV04_RS21340	COG1869	D-ribose catabolic process
FIV04_RS21375	COG4166	transmembrane transport
FIV04_RS21380	COG4174	ABC transporter (Permease)
FIV04_RS21385	COG4239	(ABC) transporter, permease
FIV04_RS21390	COG4172	Belongs to the ABC transporter superfamily
FIV04_RS21395	COG4174	ABC transporter (Permease)
FIV04_RS21400	COG4239	(ABC) transporter, permease
FIV04_RS21405	COG4166	transmembrane transport
FIV04_RS21410	COG0444	Belongs to the ABC transporter superfamily
FIV04_RS21415	COG4608	Belongs to the ABC transporter superfamily
FIV04_RS21430	COG0745	RESPONSE REGULATOR receiver
FIV04_RS21435	COG0642	Histidine kinase
FIV04_RS21455	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FIV04_RS21460	COG0573	inorganic phosphate transmembrane transporter activity
FIV04_RS21465	COG0581	inorganic phosphate transmembrane transporter activity
FIV04_RS21470	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FIV04_RS21485	COG1619	proteins homologs of microcin C7 resistance protein MccF
FIV04_RS21490	COG0583	DNA-binding transcription factor activity
FIV04_RS21500	COG1012	belongs to the aldehyde dehydrogenase family
FIV04_RS21510	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FIV04_RS21540	COG0745	RESPONSE REGULATOR receiver
FIV04_RS21545	COG2205	protein histidine kinase activity
FIV04_RS21570	COG3278	Belongs to the heme-copper respiratory oxidase family
FIV04_RS21580	COG0778	Nitroreductase
FIV04_RS21595	COG0454	-acetyltransferase
FIV04_RS21610	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
FIV04_RS21615	COG2205	protein histidine kinase activity
FIV04_RS21615	COG0784	Response regulator, receiver
FIV04_RS21625	COG3119	arylsulfatase activity
FIV04_RS21630	COG3119	arylsulfatase activity
FIV04_RS21640	COG0714	Associated with various cellular activities
FIV04_RS21670	COG0583	DNA-binding transcription factor activity
FIV04_RS21700	COG0641	radical SAM
FIV04_RS21720	COG5002	protein histidine kinase activity
FIV04_RS21720	COG2205	protein histidine kinase activity
FIV04_RS21720	COG0784	Response regulator, receiver
FIV04_RS21740	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FIV04_RS21765	COG0745	RESPONSE REGULATOR receiver
FIV04_RS21770	COG1366	Belongs to the anti-sigma-factor antagonist family
FIV04_RS21775	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FIV04_RS21850	COG1858	cytochrome C peroxidase
FIV04_RS21855	COG1858	cytochrome C peroxidase
FIV04_RS21865	COG0243	molybdopterin cofactor binding
FIV04_RS21880	COG1028	Short-chain dehydrogenase reductase Sdr
FIV04_RS21890	COG1288	antiporter activity
FIV04_RS21910	COG2165	general secretion pathway protein
FIV04_RS21920	COG1280	lysine exporter protein (LysE YggA)
FIV04_RS21935	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FIV04_RS21945	COG2116	formate transmembrane transporter activity
FIV04_RS21950	COG1648	precorrin-2 dehydrogenase activity
FIV04_RS21950	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FIV04_RS21965	COG0745	RESPONSE REGULATOR receiver
FIV04_RS21970	COG2205	protein histidine kinase activity
FIV04_RS21975	COG5001	Diguanylate cyclase
FIV04_RS21975	COG3300	MHYT domain
FIV04_RS21980	COG1301	dicarboxylic acid transport
FIV04_RS21995	COG0811	peptide transport
FIV04_RS22000	COG0811	peptide transport
FIV04_RS22005	COG0848	biopolymer transport protein
FIV04_RS22045	COG0803	Belongs to the bacterial solute-binding protein 9 family
FIV04_RS22050	COG1121	(ABC) transporter
FIV04_RS22055	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FIV04_RS22075	COG0534	Mate efflux family protein
FIV04_RS22095	COG0318	PFAM AMP-dependent synthetase and ligase
FIV04_RS22105	COG3118	belongs to the thioredoxin family
FIV04_RS22110	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FIV04_RS22125	COG1328	CTP reductase activity
FIV04_RS22130	COG0602	queuosine metabolic process
FIV04_RS22135	COG0534	Mate efflux family protein
FIV04_RS22150	COG4067	protein conserved in archaea
FIV04_RS22150	COG0189	ligase activity
FIV04_RS22175	COG0725	ABC transporter, periplasmic molybdate-binding protein
FIV04_RS22180	COG4149	molybdate abc transporter
FIV04_RS22185	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FIV04_RS22195	COG5001	Diguanylate cyclase
FIV04_RS22195	COG4251	negative regulation of phosphorylation
FIV04_RS22195	COG2203	Gaf domain
FIV04_RS22195	COG3706	GGDEF domain
FIV04_RS22205	COG3706	GGDEF domain
FIV04_RS22220	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FIV04_RS22225	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FIV04_RS22250	COG3140	Belongs to the UPF0181 family
FIV04_RS22255	COG3706	GGDEF domain
FIV04_RS22265	COG0023	Translation Initiation Factor
FIV04_RS22280	COG1181	Belongs to the D-alanine--D-alanine ligase family
FIV04_RS22290	COG0045	succinate-CoA ligase (ADP-forming) activity
FIV04_RS22290	COG1042	CoA-binding domain protein
FIV04_RS22290	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FIV04_RS22295	COG0583	DNA-binding transcription factor activity
FIV04_RS22300	COG1629	transport
FIV04_RS22300	COG4771	TonB-dependent receptor
FIV04_RS22305	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FIV04_RS22315	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FIV04_RS22320	COG1984	allophanate hydrolase subunit 2
FIV04_RS22330	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FIV04_RS22335	COG4181	ATPase activity
FIV04_RS22345	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FIV04_RS22350	COG1716	ATPase activity
FIV04_RS22350	COG5001	Diguanylate cyclase
FIV04_RS22360	COG0484	heat shock protein binding
FIV04_RS22385	COG4533	DNA binding
FIV04_RS22395	COG2050	protein possibly involved in aromatic compounds catabolism
FIV04_RS22410	COG2067	long-chain fatty acid transport protein
FIV04_RS22415	COG2267	carboxylic ester hydrolase activity
FIV04_RS22425	COG0513	Belongs to the DEAD box helicase family
FIV04_RS22440	COG0861	Integral membrane protein TerC family
FIV04_RS22445	COG0737	Belongs to the 5'-nucleotidase family
FIV04_RS22450	COG3593	DNA synthesis involved in DNA repair
FIV04_RS22460	COG0583	DNA-binding transcription factor activity
FIV04_RS22465	COG2116	formate transmembrane transporter activity
FIV04_RS22475	COG3038	cytochrome b561
FIV04_RS22490	COG2200	EAL domain
FIV04_RS22505	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FIV04_RS22515	COG0513	Belongs to the DEAD box helicase family
FIV04_RS22520	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
FIV04_RS22525	COG0814	amino acid
FIV04_RS22535	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FIV04_RS22550	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FIV04_RS22565	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FIV04_RS22570	COG2759	Belongs to the formate--tetrahydrofolate ligase family
FIV04_RS22580	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FIV04_RS22615	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FIV04_RS22620	COG0509	glycine decarboxylation via glycine cleavage system
FIV04_RS22630	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FIV04_RS22640	COG1414	Transcriptional regulator
FIV04_RS22660	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FIV04_RS22665	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FIV04_RS22670	COG1120	ATPase activity
FIV04_RS22680	COG1741	Belongs to the pirin family
FIV04_RS22685	COG2259	Doxx family
FIV04_RS22695	COG2423	ornithine cyclodeaminase activity
FIV04_RS22700	COG1522	sequence-specific DNA binding
FIV04_RS22710	COG0840	transmembrane signaling receptor activity
FIV04_RS22715	COG0840	transmembrane signaling receptor activity
FIV04_RS22725	COG3976	FMN-binding domain protein
FIV04_RS22725	COG1053	succinate dehydrogenase
FIV04_RS22725	COG0431	NADPH-dependent FMN reductase
FIV04_RS22735	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
FIV04_RS22740	COG3683	transport system, periplasmic component
FIV04_RS22750	COG3655	Transcriptional regulator
FIV04_RS22770	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FIV04_RS22795	COG4948	Mandelate Racemase Muconate Lactonizing
FIV04_RS22800	COG1053	succinate dehydrogenase
FIV04_RS22800	COG3976	FMN-binding domain protein
FIV04_RS22815	COG0583	DNA-binding transcription factor activity
FIV04_RS22820	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FIV04_RS22820	COG0302	gtp cyclohydrolase
FIV04_RS22825	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FIV04_RS22830	COG0302	gtp cyclohydrolase
FIV04_RS22845	COG3243	poly(R)-hydroxyalkanoic acid synthase
FIV04_RS22870	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FIV04_RS22870	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FIV04_RS22880	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FIV04_RS22905	COG2015	COG2015, Alkyl sulfatase and related hydrolases
FIV04_RS22920	COG3878	Protein conserved in bacteria
FIV04_RS22930	COG0431	NADPH-dependent FMN reductase
FIV04_RS22935	COG0583	DNA-binding transcription factor activity
FIV04_RS22940	COG0583	DNA-binding transcription factor activity
FIV04_RS22955	COG3604	Transcriptional regulator
FIV04_RS22975	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FIV04_RS22980	COG0583	DNA-binding transcription factor activity
FIV04_RS22985	COG3048	D-serine ammonia-lyase activity
FIV04_RS23015	COG4948	Mandelate Racemase Muconate Lactonizing
FIV04_RS23035	COG0848	biopolymer transport protein
FIV04_RS23040	COG0811	peptide transport
FIV04_RS23045	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
FIV04_RS23060	COG1192	Involved in chromosome partitioning
FIV04_RS23100	COG0415	Belongs to the DNA photolyase family
FIV04_RS23110	COG4774	siderophore transport
FIV04_RS23125	COG2207	Transcriptional regulator
FIV04_RS23130	COG0346	lactoylglutathione lyase activity
FIV04_RS23140	COG3708	Transcriptional regulator
FIV04_RS23140	COG2207	Transcriptional regulator
FIV04_RS23150	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FIV04_RS23150	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FIV04_RS23160	COG1733	regulation of RNA biosynthetic process
FIV04_RS23195	COG1609	Transcriptional regulator
FIV04_RS23230	COG3250	beta-galactosidase activity
FIV04_RS23240	COG4580	involved in the transport of maltose and maltodextrins
FIV04_RS23255	COG2211	Major facilitator Superfamily
FIV04_RS23260	COG1733	regulation of RNA biosynthetic process
FIV04_RS23270	COG1271	oxidase subunit
FIV04_RS23275	COG1294	oxidase, subunit
FIV04_RS23280	COG1320	monovalent cation:proton antiporter activity
FIV04_RS23285	COG2212	antiporter activity
FIV04_RS23290	COG1863	multisubunit Na H antiporter MnhE subunit
FIV04_RS23295	COG0651	ATP synthesis coupled electron transport
FIV04_RS23300	COG1006	Multisubunit Na H antiporter MnhC subunit
FIV04_RS23305	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FIV04_RS23305	COG2111	Na H antiporter
FIV04_RS23315	COG0589	response to stress
FIV04_RS23325	COG2199	diguanylate cyclase activity
FIV04_RS23340	COG0583	DNA-binding transcription factor activity
FIV04_RS23365	COG1902	pentaerythritol trinitrate reductase activity
FIV04_RS23370	COG0583	DNA-binding transcription factor activity
FIV04_RS23385	COG0697	spore germination
FIV04_RS23390	COG0583	DNA-binding transcription factor activity
FIV04_RS23400	COG0300	oxidoreductase activity
FIV04_RS23405	COG1280	lysine exporter protein (LysE YggA)
FIV04_RS23430	COG2207	Transcriptional regulator
FIV04_RS23435	COG2207	Transcriptional regulator
FIV04_RS23435	COG1917	Cupin 2, conserved barrel domain protein
FIV04_RS23455	COG0583	DNA-binding transcription factor activity
FIV04_RS23475	COG1028	Short-chain dehydrogenase reductase Sdr
FIV04_RS23480	COG0583	DNA-binding transcription factor activity
FIV04_RS23505	COG1012	belongs to the aldehyde dehydrogenase family
FIV04_RS23515	COG0778	Nitroreductase
FIV04_RS23660	COG2026	Addiction module toxin, RelE StbE family
FIV04_RS23685	COG0583	DNA-binding transcription factor activity
FIV04_RS23780	COG3547	Transposase (IS116 IS110 IS902 family)
FIV04_RS23805	COG0210	DNA helicase
FIV04_RS23825	COG0494	nUDIX hydrolase
FIV04_RS23865	COG1683	Conserved Protein
FIV04_RS23885	COG3710	Transcriptional regulator
FIV04_RS23890	COG1566	PFAM secretion protein HlyD family protein
FIV04_RS23900	COG0583	DNA-binding transcription factor activity
FIV04_RS23915	COG1538	Outer membrane efflux protein
FIV04_RS23930	COG2067	long-chain fatty acid transport protein
FIV04_RS23935	COG5001	Diguanylate cyclase
FIV04_RS23935	COG3300	MHYT domain
FIV04_RS23960	COG1454	alcohol dehydrogenase
FIV04_RS23975	COG1280	lysine exporter protein (LysE YggA)
FIV04_RS23980	COG0583	DNA-binding transcription factor activity
FIV04_RS23995	COG1733	regulation of RNA biosynthetic process
FIV04_RS24010	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FIV04_RS24020	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FIV04_RS24045	COG0840	transmembrane signaling receptor activity
FIV04_RS24075	COG0300	oxidoreductase activity
FIV04_RS24085	COG4771	TonB-dependent receptor
FIV04_RS24090	COG2382	esterase
FIV04_RS24100	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FIV04_RS24135	COG0784	Response regulator, receiver
FIV04_RS24135	COG2205	protein histidine kinase activity
FIV04_RS24150	COG0693	protein deglycase activity
FIV04_RS24155	COG1882	Formate acetyltransferase
FIV04_RS24165	COG1028	Short-chain dehydrogenase reductase Sdr
FIV04_RS24175	COG1028	Short-chain dehydrogenase reductase Sdr
FIV04_RS24205	COG2165	general secretion pathway protein
FIV04_RS24245	COG3437	response regulator, receiver
FIV04_RS24245	COG2770	Histidine kinase
FIV04_RS24265	COG0702	epimerase
FIV04_RS24270	COG2207	Transcriptional regulator
FIV04_RS24280	COG2233	PERMEase
FIV04_RS24285	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FIV04_RS24295	COG2197	response regulator
FIV04_RS24305	COG2207	Transcriptional regulator
FIV04_RS24305	COG1917	Cupin 2, conserved barrel domain protein
FIV04_RS24315	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FIV04_RS24320	COG1121	(ABC) transporter
FIV04_RS24345	COG4774	siderophore transport
FIV04_RS24375	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FIV04_RS24385	COG1609	Transcriptional regulator
FIV04_RS24435	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FIV04_RS24445	COG2015	COG2015, Alkyl sulfatase and related hydrolases
FIV04_RS24450	COG0583	DNA-binding transcription factor activity
FIV04_RS24465	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FIV04_RS24490	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FIV04_RS24505	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FIV04_RS24515	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FIV04_RS24520	COG1309	transcriptional regulator
FIV04_RS24530	COG0456	acetyltransferase
FIV04_RS24535	COG0730	response to heat
FIV04_RS24550	COG2801	Transposase and inactivated derivatives
FIV04_RS24585	COG1686	Belongs to the peptidase S11 family
FIV04_RS24590	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FIV04_RS24595	COG0583	DNA-binding transcription factor activity
FIV04_RS24630	COG2199	diguanylate cyclase activity
FIV04_RS24630	COG2200	EAL domain
FIV04_RS24655	COG1929	Belongs to the glycerate kinase type-1 family
FIV04_RS24665	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FIV04_RS24665	COG1263	PTS System
FIV04_RS24670	COG2188	Transcriptional regulator
FIV04_RS24675	COG1120	ATPase activity
FIV04_RS24680	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FIV04_RS24685	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FIV04_RS24690	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FIV04_RS24695	COG4772	TonB-dependent receptor
FIV04_RS24720	COG4264	IucA IucC family
FIV04_RS24725	COG0019	diaminopimelate decarboxylase activity
FIV04_RS24765	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FIV04_RS24790	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FIV04_RS24835	COG0346	lactoylglutathione lyase activity
FIV04_RS24865	COG0667	Aldo Keto reductase
FIV04_RS24920	COG0840	transmembrane signaling receptor activity
FIV04_RS24925	COG1073	alpha beta
FIV04_RS24940	COG1028	Short-chain dehydrogenase reductase Sdr
FIV04_RS24950	COG0583	DNA-binding transcription factor activity
FIV04_RS24960	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
FIV04_RS24990	COG0069	glutamate synthase activity
FIV04_RS25020	COG0583	DNA-binding transcription factor activity
FIV04_RS25025	COG0783	Belongs to the Dps family
FIV04_RS25060	COG0384	phenazine biosynthesis protein PhzF
FIV04_RS25065	COG0678	peroxiredoxin activity
FIV04_RS25070	COG2814	Major facilitator Superfamily
FIV04_RS25075	COG0450	alkyl hydroperoxide reductase
FIV04_RS25085	COG0789	Transcriptional regulator
FIV04_RS25095	COG1653	transport
FIV04_RS25100	COG0840	transmembrane signaling receptor activity
FIV04_RS25105	COG0371	Dehydrogenase
FIV04_RS25115	COG1105	Belongs to the carbohydrate kinase PfkB family
FIV04_RS25120	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FIV04_RS25120	COG0517	IMP dehydrogenase activity
FIV04_RS25125	COG4702	Belongs to the UPF0303 family
FIV04_RS25130	COG0673	inositol 2-dehydrogenase activity
FIV04_RS25135	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FIV04_RS25135	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FIV04_RS25135	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FIV04_RS25140	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FIV04_RS25145	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FIV04_RS25150	COG1882	Formate acetyltransferase
FIV04_RS25155	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FIV04_RS25165	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FIV04_RS25170	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FIV04_RS25175	COG2207	Transcriptional regulator
FIV04_RS25220	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FIV04_RS25230	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FIV04_RS25255	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FIV04_RS25260	COG3070	regulator of competence-specific genes
FIV04_RS25310	COG2974	May be involved in recombination
FIV04_RS25400	COG4974	Belongs to the 'phage' integrase family
FIV04_RS25465	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FIV04_RS25485	COG2205	protein histidine kinase activity
FIV04_RS25490	COG0745	RESPONSE REGULATOR receiver
FIV04_RS25520	COG0789	Transcriptional regulator
FIV04_RS25545	COG0784	Response regulator, receiver
FIV04_RS25545	COG2205	protein histidine kinase activity
FIV04_RS25620	COG0592	DNA-directed DNA polymerase activity
FIV04_RS25720	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FIV04_RS25755	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FIV04_RS26155	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FIV04_RS26160	COG1085	galactose-1-phosphate uridylyltransferase
FIV04_RS26175	COG3064	Membrane
FIV04_RS26185	COG2165	general secretion pathway protein
FIV04_RS26205	COG2203	Gaf domain
FIV04_RS26205	COG2199	diguanylate cyclase activity
FIV04_RS26265	COG4115	mRNA cleavage
FIV04_RS26270	COG2161	toxin-antitoxin pair type II binding
FIV04_RS26410	COG0784	Response regulator, receiver
FIV04_RS26410	COG3437	response regulator, receiver
FIV04_RS26465	COG1609	Transcriptional regulator
FIV04_RS26465	COG2207	Transcriptional regulator
FIV04_RS26470	COG2017	converts alpha-aldose to the beta-anomer
FIV04_RS26480	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
FIV04_RS26515	COG2770	Histidine kinase
FIV04_RS26515	COG3437	response regulator, receiver
FIV04_RS26600	COG0484	heat shock protein binding
FIV04_RS26675	COG1192	Involved in chromosome partitioning