locus-tag	class	description
GGC03_RS00010	COG0592	DNA-directed DNA polymerase activity
GGC03_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GGC03_RS00020	COG0187	DNA topoisomerase II activity
GGC03_RS00025	COG0071	Belongs to the small heat shock protein (HSP20) family
GGC03_RS00030	COG3977	Valine--pyruvate aminotransferase
GGC03_RS00035	COG0751	glycine-tRNA ligase activity
GGC03_RS00040	COG0752	glycyl-tRNA synthetase alpha subunit
GGC03_RS00045	COG2119	membrane
GGC03_RS00055	COG0425	Belongs to the sulfur carrier protein TusA family
GGC03_RS00070	COG0604	alcohol dehydrogenase
GGC03_RS00080	COG0129	dihydroxy-acid dehydratase activity
GGC03_RS00085	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GGC03_RS00090	COG3978	acetolactate synthase activity
GGC03_RS00100	COG0606	chelatase, subunit chli
GGC03_RS00195	COG0204	Acyl-transferase
GGC03_RS00200	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GGC03_RS00205	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GGC03_RS00215	COG3084	Protein conserved in bacteria
GGC03_RS00220	COG4326	sporulation control protein
GGC03_RS00225	COG1272	protein, Hemolysin III
GGC03_RS00235	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GGC03_RS00240	COG0569	domain protein
GGC03_RS00245	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GGC03_RS00245	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GGC03_RS00255	COG0242	peptide deformylase activity
GGC03_RS00260	COG0758	DNA mediated transformation
GGC03_RS00265	COG2922	Belongs to the Smg family
GGC03_RS00270	COG0551	DNA topoisomerase type I activity
GGC03_RS00275	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GGC03_RS00280	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GGC03_RS00290	COG0408	coproporphyrinogen oxidase activity
GGC03_RS00305	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GGC03_RS00345	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GGC03_RS00355	COG2204	response regulator
GGC03_RS00360	COG3852	Histidine kinase
GGC03_RS00365	COG0174	glutamine synthetase
GGC03_RS00370	COG1217	gtp-binding protein TYPA
GGC03_RS00380	COG1295	ribonuclease BN
GGC03_RS00385	COG1490	D-aminoacyl-tRNA deacylase activity
GGC03_RS00390	COG0456	acetyltransferase
GGC03_RS00400	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
GGC03_RS00410	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GGC03_RS00415	COG3031	protein transport across the cell outer membrane
GGC03_RS00425	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GGC03_RS00430	COG1459	type II secretion system
GGC03_RS00435	COG2165	general secretion pathway protein
GGC03_RS00440	COG2165	general secretion pathway protein
GGC03_RS00445	COG2165	general secretion pathway protein
GGC03_RS00450	COG4795	General secretion pathway protein
GGC03_RS00455	COG3156	type II secretion system protein K
GGC03_RS00460	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
GGC03_RS00465	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
GGC03_RS00485	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GGC03_RS00495	COG2183	response to ionizing radiation
GGC03_RS00505	COG0596	Alpha beta hydrolase
GGC03_RS00515	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
GGC03_RS00515	COG0316	Belongs to the HesB IscA family
GGC03_RS00520	COG0494	nUDIX hydrolase
GGC03_RS00525	COG1218	3'(2'),5'-bisphosphate nucleotidase
GGC03_RS00530	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GGC03_RS00535	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GGC03_RS00540	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GGC03_RS00545	COG1758	RNA polymerase activity
GGC03_RS00550	COG0194	GDP metabolic process
GGC03_RS00555	COG1595	DNA-templated transcription, initiation
GGC03_RS00585	COG0848	biopolymer transport protein
GGC03_RS00595	COG2252	PERMEase
GGC03_RS00600	COG2831	hemolysin activation secretion protein
GGC03_RS00605	COG3210	domain, Protein
GGC03_RS00615	COG1561	YicC-like family, N-terminal region
GGC03_RS00620	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
GGC03_RS00625	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GGC03_RS00630	COG1560	Kdo2-lipid A biosynthetic process
GGC03_RS00635	COG1560	Kdo2-lipid A biosynthetic process
GGC03_RS00640	COG1309	transcriptional regulator
GGC03_RS00645	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GGC03_RS00650	COG2003	Belongs to the UPF0758 family
GGC03_RS00655	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GGC03_RS00675	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GGC03_RS00680	COG0859	PFAM glycosyl transferase family 9
GGC03_RS00685	COG0463	Glycosyl transferase, family 2
GGC03_RS00690	COG0859	PFAM glycosyl transferase family 9
GGC03_RS00695	COG3642	lipopolysaccharide core region biosynthetic process
GGC03_RS00710	COG1519	Transferase
GGC03_RS00725	COG0859	PFAM glycosyl transferase family 9
GGC03_RS00755	COG1086	Polysaccharide biosynthesis protein
GGC03_RS00760	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GGC03_RS00770	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
GGC03_RS00775	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GGC03_RS00785	COG2089	acid synthase
GGC03_RS00795	COG0318	PFAM AMP-dependent synthetase and ligase
GGC03_RS00805	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
GGC03_RS00820	COG4310	Domain of unknown function (DUF2172)
GGC03_RS00830	COG2226	methyltransferase
GGC03_RS00870	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GGC03_RS00875	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GGC03_RS00880	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
GGC03_RS00880	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
GGC03_RS00885	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GGC03_RS00925	COG1494	fructose-1,6-bisphosphatase
GGC03_RS00930	COG3074	FtsZ-dependent cytokinesis
GGC03_RS00935	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GGC03_RS00940	COG0460	homoserine dehydrogenase
GGC03_RS00940	COG0527	aspartate kinase activity
GGC03_RS00945	COG0626	cystathionine gamma-synthase activity
GGC03_RS00950	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
GGC03_RS00955	COG0281	malic enzyme
GGC03_RS00965	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GGC03_RS00970	COG1609	Transcriptional regulator
GGC03_RS00975	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GGC03_RS00980	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GGC03_RS01005	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GGC03_RS01010	COG1053	succinate dehydrogenase
GGC03_RS01015	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
GGC03_RS01020	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GGC03_RS01055	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GGC03_RS01070	COG1045	serine acetyltransferase
GGC03_RS01075	COG1695	Transcriptional regulator
GGC03_RS01080	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
GGC03_RS01085	COG1573	uracil-dna glycosylase
GGC03_RS01090	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GGC03_RS01100	COG1253	flavin adenine dinucleotide binding
GGC03_RS01115	COG0151	Belongs to the GarS family
GGC03_RS01125	COG0789	Transcriptional regulator
GGC03_RS01130	COG2199	diguanylate cyclase activity
GGC03_RS01135	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
GGC03_RS01140	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GGC03_RS01145	COG2264	protein methyltransferase activity
GGC03_RS01150	COG0439	Biotin carboxylase
GGC03_RS01155	COG0511	ligase activity, forming carbon-carbon bonds
GGC03_RS01160	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GGC03_RS01165	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GGC03_RS01180	COG2814	Major facilitator Superfamily
GGC03_RS01185	COG2205	protein histidine kinase activity
GGC03_RS01185	COG0784	Response regulator, receiver
GGC03_RS01195	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GGC03_RS01205	COG2095	MarC family integral membrane protein
GGC03_RS01215	COG4232	protein-disulfide reductase activity
GGC03_RS01220	COG1438	arginine binding
GGC03_RS01225	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
GGC03_RS01230	COG0540	Belongs to the ATCase OTCase family
GGC03_RS01235	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GGC03_RS01250	COG1288	antiporter activity
GGC03_RS01255	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GGC03_RS01260	COG1027	Aspartate ammonia-lyase
GGC03_RS01340	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GGC03_RS01350	COG1012	belongs to the aldehyde dehydrogenase family
GGC03_RS01360	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GGC03_RS01365	COG3954	Phosphoribulokinase
GGC03_RS01375	COG0429	hydrolase of the alpha beta-hydrolase fold
GGC03_RS01385	COG0488	(ABC) transporter
GGC03_RS01405	COG1047	Peptidyl-prolyl cis-trans
GGC03_RS01415	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GGC03_RS01425	COG0402	S-adenosylhomocysteine deaminase activity
GGC03_RS01430	COG0557	exoribonuclease II activity
GGC03_RS01435	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GGC03_RS01440	COG0051	transcription antitermination factor activity, RNA binding
GGC03_RS01445	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GGC03_RS01450	COG0088	Forms part of the polypeptide exit tunnel
GGC03_RS01465	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GGC03_RS01470	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GGC03_RS01475	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GGC03_RS01490	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GGC03_RS01505	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GGC03_RS01520	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GGC03_RS01535	COG1841	ribosomal large subunit assembly
GGC03_RS01540	COG0200	Binds to the 23S rRNA
GGC03_RS01545	COG0201	protein transport
GGC03_RS01550	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GGC03_RS01555	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GGC03_RS01560	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GGC03_RS01570	COG0202	RNA polymerase activity
GGC03_RS01575	COG0203	ribosomal protein L17
GGC03_RS01585	COG0545	Peptidyl-prolyl cis-trans isomerase
GGC03_RS01600	COG2153	protein acetylation
GGC03_RS01610	COG0737	Belongs to the 5'-nucleotidase family
GGC03_RS01615	COG1648	precorrin-2 dehydrogenase activity
GGC03_RS01615	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GGC03_RS01630	COG3273	potassium ion transport
GGC03_RS01630	COG0471	metal ion transport
GGC03_RS01635	COG0529	Catalyzes the synthesis of activated sulfate
GGC03_RS01645	COG0735	belongs to the Fur family
GGC03_RS01655	COG3437	response regulator, receiver
GGC03_RS01685	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GGC03_RS01690	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GGC03_RS01695	COG0175	sulfate reduction
GGC03_RS01750	COG0646	methionine synthase
GGC03_RS01750	COG1410	methionine synthase
GGC03_RS01755	COG2239	Acts as a magnesium transporter
GGC03_RS01760	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GGC03_RS01765	COG1660	Displays ATPase and GTPase activities
GGC03_RS01770	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GGC03_RS01775	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GGC03_RS01785	COG1137	ATPase activity
GGC03_RS01790	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
GGC03_RS01800	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
GGC03_RS01805	COG0517	IMP dehydrogenase activity
GGC03_RS01805	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GGC03_RS01815	COG1127	ABC transporter
GGC03_RS01820	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GGC03_RS01825	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GGC03_RS01830	COG2854	intermembrane phospholipid transfer
GGC03_RS01840	COG5007	Belongs to the BolA IbaG family
GGC03_RS01850	COG0204	Acyl-transferase
GGC03_RS01855	COG2235	arginine
GGC03_RS01875	COG0589	response to stress
GGC03_RS01885	COG2358	TRAP transporter, solute receptor (TAXI family
GGC03_RS01890	COG1438	arginine binding
GGC03_RS01895	COG0039	L-malate dehydrogenase activity
GGC03_RS01905	COG0251	oxidation-reduction process
GGC03_RS01910	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
GGC03_RS01925	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
GGC03_RS01930	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GGC03_RS01940	COG0564	pseudouridine synthase activity
GGC03_RS01945	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GGC03_RS01955	COG4269	membrane
GGC03_RS01965	COG0525	valine-tRNA ligase activity
GGC03_RS01970	COG2927	DNA polymerase III (CHI subunit)
GGC03_RS01980	COG0795	lipopolysaccharide-transporting ATPase activity
GGC03_RS01985	COG0795	lipopolysaccharide-transporting ATPase activity
GGC03_RS01990	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GGC03_RS01995	COG1546	Belongs to the CinA family
GGC03_RS02000	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GGC03_RS02005	COG2137	regulation of response to DNA damage stimulus
GGC03_RS02015	COG0527	aspartate kinase activity
GGC03_RS02065	COG3630	sodium ion export across plasma membrane
GGC03_RS02070	COG5016	pyruvate
GGC03_RS02070	COG0511	ligase activity, forming carbon-carbon bonds
GGC03_RS02075	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
GGC03_RS02085	COG1238	metal cluster binding
GGC03_RS02090	COG0612	Peptidase, M16
GGC03_RS02095	COG2918	glutathione biosynthetic process
GGC03_RS02105	COG1854	S-ribosylhomocysteine lyase activity
GGC03_RS02120	COG0582	viral genome integration into host DNA
GGC03_RS02150	COG0328	RNA-DNA hybrid ribonuclease activity
GGC03_RS02190	COG2203	Gaf domain
GGC03_RS02190	COG3706	GGDEF domain
GGC03_RS02190	COG4251	negative regulation of phosphorylation
GGC03_RS02190	COG5001	Diguanylate cyclase
GGC03_RS02200	COG1879	ABC-type sugar transport system periplasmic component
GGC03_RS02205	COG0840	transmembrane signaling receptor activity
GGC03_RS02220	COG0840	transmembrane signaling receptor activity
GGC03_RS02225	COG5001	Diguanylate cyclase
GGC03_RS02225	COG4251	negative regulation of phosphorylation
GGC03_RS02225	COG3706	GGDEF domain
GGC03_RS02225	COG2203	Gaf domain
GGC03_RS02250	COG0640	Transcriptional regulator
GGC03_RS02295	COG2003	Belongs to the UPF0758 family
GGC03_RS02305	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
GGC03_RS02330	COG3437	response regulator, receiver
GGC03_RS02395	COG0473	3-isopropylmalate dehydrogenase activity
GGC03_RS02400	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GGC03_RS02420	COG0583	DNA-binding transcription factor activity
GGC03_RS02425	COG1022	Amp-dependent synthetase and ligase
GGC03_RS02430	COG0028	Belongs to the TPP enzyme family
GGC03_RS02435	COG0440	acetolactate synthase activity
GGC03_RS02440	COG0584	glycerophosphoryl diester phosphodiesterase
GGC03_RS02445	COG2271	Major facilitator Superfamily
GGC03_RS02450	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GGC03_RS02460	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GGC03_RS02470	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
GGC03_RS02475	COG3079	Belongs to the UPF0149 family
GGC03_RS02480	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GGC03_RS02485	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GGC03_RS02510	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GGC03_RS02515	COG1595	DNA-templated transcription, initiation
GGC03_RS02530	COG3086	response to oxidative stress
GGC03_RS02535	COG0481	GTPase activity
GGC03_RS02545	COG0571	ribonuclease III activity
GGC03_RS02550	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GGC03_RS02555	COG1381	Involved in DNA repair and RecF pathway recombination
GGC03_RS02560	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
GGC03_RS02565	COG0736	holo-[acyl-carrier-protein] synthase activity
GGC03_RS02570	COG3850	Histidine kinase
GGC03_RS02570	COG3437	response regulator, receiver
GGC03_RS02570	COG2205	protein histidine kinase activity
GGC03_RS02570	COG4999	Histidine kinase
GGC03_RS02575	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GGC03_RS02580	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GGC03_RS02585	COG3956	TIGRFAM MazG family protein
GGC03_RS02595	COG0148	phosphopyruvate hydratase activity
GGC03_RS02600	COG0617	tRNA 3'-terminal CCA addition
GGC03_RS02605	COG3267	Type II secretory pathway component ExeA
GGC03_RS02605	COG3409	Peptidoglycan-binding domain 1 protein
GGC03_RS02615	COG4991	sh3 domain protein
GGC03_RS02620	COG0306	phosphate transporter
GGC03_RS02625	COG1392	Phosphate transport regulator
GGC03_RS02630	COG3025	triphosphatase activity
GGC03_RS02635	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GGC03_RS02645	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
GGC03_RS02650	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
GGC03_RS02650	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
GGC03_RS02660	COG0745	RESPONSE REGULATOR receiver
GGC03_RS02675	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GGC03_RS02695	COG0083	homoserine kinase activity
GGC03_RS02700	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GGC03_RS02705	COG2860	membrane
GGC03_RS02710	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GGC03_RS02715	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
GGC03_RS02725	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GGC03_RS02740	COG1846	Transcriptional regulator
GGC03_RS02745	COG0534	Mate efflux family protein
GGC03_RS02750	COG2204	response regulator
GGC03_RS02760	COG0667	Aldo Keto reductase
GGC03_RS02770	COG3066	DNA modification
GGC03_RS02775	COG0494	nUDIX hydrolase
GGC03_RS02785	COG0730	response to heat
GGC03_RS02790	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GGC03_RS02795	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GGC03_RS02800	COG1283	sodium-dependent phosphate transmembrane transporter activity
GGC03_RS02805	COG0583	DNA-binding transcription factor activity
GGC03_RS02810	COG0640	Transcriptional regulator
GGC03_RS02815	COG0268	Binds directly to 16S ribosomal RNA
GGC03_RS02820	COG0728	peptidoglycan biosynthetic process
GGC03_RS02825	COG0196	riboflavin kinase activity
GGC03_RS02840	COG1047	Peptidyl-prolyl cis-trans
GGC03_RS02845	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GGC03_RS02850	COG1966	Carbon starvation protein
GGC03_RS02860	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GGC03_RS02865	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
GGC03_RS02870	COG2971	BadF BadG BcrA BcrD
GGC03_RS02880	COG1737	Transcriptional regulator
GGC03_RS02890	COG3279	Response regulator of the LytR AlgR family
GGC03_RS02895	COG3275	phosphorelay sensor kinase activity
GGC03_RS02900	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GGC03_RS02905	COG0287	Prephenate dehydrogenase
GGC03_RS02905	COG1605	Chorismate mutase
GGC03_RS02910	COG0739	heme binding
GGC03_RS02920	COG0488	(ABC) transporter
GGC03_RS02925	COG0741	lytic transglycosylase activity
GGC03_RS02930	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
GGC03_RS02935	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
GGC03_RS02940	COG5001	Diguanylate cyclase
GGC03_RS02945	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GGC03_RS02950	COG1605	Chorismate mutase
GGC03_RS02950	COG0077	Prephenate dehydratase
GGC03_RS02955	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GGC03_RS02960	COG0741	lytic transglycosylase activity
GGC03_RS02965	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GGC03_RS02970	COG0564	pseudouridine synthase activity
GGC03_RS02980	COG0542	response to heat
GGC03_RS03025	COG0483	inositol monophosphate 1-phosphatase activity
GGC03_RS03035	COG1959	2 iron, 2 sulfur cluster binding
GGC03_RS03045	COG0822	iron-sulfur transferase activity
GGC03_RS03065	COG0633	Ferredoxin
GGC03_RS03070	COG2975	iron-sulfur cluster assembly
GGC03_RS03075	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GGC03_RS03085	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GGC03_RS03090	COG0583	DNA-binding transcription factor activity
GGC03_RS03100	COG0583	DNA-binding transcription factor activity
GGC03_RS03105	COG1022	Amp-dependent synthetase and ligase
GGC03_RS03110	COG2169	Transcriptional regulator
GGC03_RS03135	COG4964	Belongs to the GSP D family
GGC03_RS03185	COG2169	Transcriptional regulator
GGC03_RS03190	COG1486	melibiose metabolic process
GGC03_RS03195	COG2211	Major facilitator Superfamily
GGC03_RS03205	COG3408	Glycogen debranching enzyme
GGC03_RS03205	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
GGC03_RS03220	COG1309	transcriptional regulator
GGC03_RS03225	COG0531	amino acid
GGC03_RS03230	COG2731	YhcH YjgK YiaL family protein
GGC03_RS03235	COG3250	beta-galactosidase activity
GGC03_RS03240	COG1609	Transcriptional regulator
GGC03_RS03245	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GGC03_RS03250	COG1085	galactose-1-phosphate uridylyltransferase
GGC03_RS03260	COG2017	converts alpha-aldose to the beta-anomer
GGC03_RS03270	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GGC03_RS03280	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GGC03_RS03280	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GGC03_RS03280	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GGC03_RS03285	COG2207	Transcriptional regulator
GGC03_RS03295	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GGC03_RS03305	COG2171	N-acyltransferase activity
GGC03_RS03310	COG0450	alkyl hydroperoxide reductase
GGC03_RS03315	COG0583	DNA-binding transcription factor activity
GGC03_RS03320	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GGC03_RS03345	COG0517	IMP dehydrogenase activity
GGC03_RS03350	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GGC03_RS03360	COG1862	Preprotein translocase
GGC03_RS03365	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GGC03_RS03370	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GGC03_RS03385	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
GGC03_RS03390	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GGC03_RS03395	COG0826	peptidase U32
GGC03_RS03405	COG0745	RESPONSE REGULATOR receiver
GGC03_RS03410	COG5002	protein histidine kinase activity
GGC03_RS03420	COG0248	Ppx GppA phosphatase
GGC03_RS03425	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GGC03_RS03430	COG0573	inorganic phosphate transmembrane transporter activity
GGC03_RS03435	COG0581	inorganic phosphate transmembrane transporter activity
GGC03_RS03440	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GGC03_RS03445	COG0704	Plays a role in the regulation of phosphate uptake
GGC03_RS03460	COG3141	response to X-ray
GGC03_RS03465	COG1309	transcriptional regulator
GGC03_RS03470	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GGC03_RS03490	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
GGC03_RS03495	COG1074	ATP-dependent DNA helicase activity
GGC03_RS03500	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GGC03_RS03520	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
GGC03_RS03525	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GGC03_RS03530	COG2166	iron-sulfur cluster assembly
GGC03_RS03540	COG1426	Protein conserved in bacteria
GGC03_RS03545	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GGC03_RS03550	COG0124	histidyl-tRNA synthetase
GGC03_RS03555	COG2976	Protein conserved in bacteria
GGC03_RS03560	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GGC03_RS03565	COG1160	GTP binding
GGC03_RS03575	COG2199	diguanylate cyclase activity
GGC03_RS03575	COG2203	Gaf domain
GGC03_RS03590	COG0517	IMP dehydrogenase activity
GGC03_RS03590	COG0516	GMP reductase activity
GGC03_RS03605	COG1584	GPR1 FUN34 yaaH family protein
GGC03_RS03610	COG1115	amino acid carrier protein
GGC03_RS03615	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GGC03_RS03635	COG2873	o-acetylhomoserine
GGC03_RS03640	COG0835	chemotaxis
GGC03_RS03640	COG0784	Response regulator, receiver
GGC03_RS03645	COG0204	Acyl-transferase
GGC03_RS03665	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GGC03_RS03670	COG0668	transmembrane transport
GGC03_RS03695	COG2867	negative regulation of translational initiation
GGC03_RS03700	COG2914	Belongs to the UPF0125 (RnfH) family
GGC03_RS03705	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GGC03_RS03710	COG0497	DNA recombination
GGC03_RS03715	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GGC03_RS03720	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GGC03_RS03725	COG1301	dicarboxylic acid transport
GGC03_RS03730	COG0443	Heat shock 70 kDa protein
GGC03_RS03745	COG4970	Tfp pilus assembly protein FimT
GGC03_RS03765	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
GGC03_RS03775	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
GGC03_RS03780	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GGC03_RS03780	COG0047	phosphoribosylformylglycinamidine synthase activity
GGC03_RS03805	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GGC03_RS03810	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GGC03_RS03815	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GGC03_RS03820	COG1187	pseudouridine synthase activity
GGC03_RS03825	COG2840	Smr protein MutS2
GGC03_RS03850	COG3104	oligopeptide transport
GGC03_RS03855	COG0367	asparagine synthase
GGC03_RS03860	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GGC03_RS03860	COG4651	solute:proton antiporter activity
GGC03_RS03865	COG1940	carbohydrate kinase activity
GGC03_RS03865	COG1846	Transcriptional regulator
GGC03_RS03870	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GGC03_RS03875	COG1263	PTS System
GGC03_RS03875	COG2190	(PTS) system
GGC03_RS03875	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GGC03_RS03905	COG0596	Alpha beta hydrolase
GGC03_RS03910	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
GGC03_RS03915	COG0033	Phosphoglucomutase
GGC03_RS03925	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GGC03_RS03940	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
GGC03_RS03945	COG1053	succinate dehydrogenase
GGC03_RS03950	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GGC03_RS03955	COG0567	Dehydrogenase, E1 component
GGC03_RS03960	COG0508	dehydrogenase complex catalyzes the overall conversion of
GGC03_RS04000	COG3098	single-species biofilm formation
GGC03_RS04005	COG0564	pseudouridine synthase activity
GGC03_RS04015	COG0142	geranyltranstransferase activity
GGC03_RS04020	COG1722	exodeoxyribonuclease VII activity
GGC03_RS04025	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GGC03_RS04035	COG0301	tRNA thio-modification
GGC03_RS04035	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GGC03_RS04040	COG0583	DNA-binding transcription factor activity
GGC03_RS04055	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
GGC03_RS04065	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GGC03_RS04070	COG1611	Belongs to the LOG family
GGC03_RS04085	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GGC03_RS04085	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GGC03_RS04095	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
GGC03_RS04110	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GGC03_RS04115	COG1393	Belongs to the ArsC family
GGC03_RS04140	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
GGC03_RS04145	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
GGC03_RS04150	COG0437	4 iron, 4 sulfur cluster binding
GGC03_RS04155	COG3301	Polysulphide reductase, NrfD
GGC03_RS04160	COG1138	Cytochrome C-type biogenesis protein
GGC03_RS04165	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GGC03_RS04170	COG3088	subunit of a heme lyase
GGC03_RS04170	COG4235	cytochrome complex assembly
GGC03_RS04180	COG2837	iron assimilation
GGC03_RS04195	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GGC03_RS04205	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
GGC03_RS04215	COG1516	flagellar protein fliS
GGC03_RS04235	COG1677	Flagellar hook-basal body complex protein FliE
GGC03_RS04245	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GGC03_RS04295	COG1987	bacterial-type flagellum assembly
GGC03_RS04300	COG1684	flagellar biosynthetic protein fliR
GGC03_RS04315	COG2890	protein-(glutamine-N5) methyltransferase activity
GGC03_RS04320	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GGC03_RS04330	COG2860	membrane
GGC03_RS04335	COG3101	peptidyl-lysine hydroxylation
GGC03_RS04365	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GGC03_RS04370	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GGC03_RS04375	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GGC03_RS04390	COG0101	tRNA pseudouridine synthase activity
GGC03_RS04395	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GGC03_RS04400	COG0285	dihydrofolate synthase activity
GGC03_RS04405	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
GGC03_RS04410	COG1286	toxin biosynthetic process
GGC03_RS04415	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GGC03_RS04420	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GGC03_RS04425	COG1121	(ABC) transporter
GGC03_RS04430	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
GGC03_RS04435	COG4977	sequence-specific DNA binding
GGC03_RS04440	COG1918	ferrous iron import across plasma membrane
GGC03_RS04445	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
GGC03_RS04460	COG0018	arginyl-trna synthetase
GGC03_RS04465	COG3102	Protein conserved in bacteria
GGC03_RS04470	COG1025	Belongs to the peptidase M16 family
GGC03_RS04475	COG2062	phosphohistidine phosphatase, SixA
GGC03_RS04505	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
GGC03_RS04510	COG0784	Response regulator, receiver
GGC03_RS04510	COG2198	Histidine kinase
GGC03_RS04510	COG0643	Histidine kinase
GGC03_RS04515	COG2201	protein-glutamate methylesterase activity
GGC03_RS04520	COG1192	Involved in chromosome partitioning
GGC03_RS04530	COG0835	chemotaxis
GGC03_RS04540	COG4133	protoheme IX ABC transporter activity
GGC03_RS04545	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GGC03_RS04550	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GGC03_RS04555	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GGC03_RS04565	COG1138	Cytochrome C-type biogenesis protein
GGC03_RS04570	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GGC03_RS04575	COG4235	cytochrome complex assembly
GGC03_RS04575	COG3088	subunit of a heme lyase
GGC03_RS04585	COG2853	Lipoprotein
GGC03_RS04590	COG2067	long-chain fatty acid transport protein
GGC03_RS04595	COG2067	long-chain fatty acid transport protein
GGC03_RS04610	COG0183	Belongs to the thiolase family
GGC03_RS04620	COG0778	Nitroreductase
GGC03_RS04625	COG0583	DNA-binding transcription factor activity
GGC03_RS04630	COG0745	RESPONSE REGULATOR receiver
GGC03_RS04640	COG2832	Protein of unknown function (DUF454)
GGC03_RS04645	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GGC03_RS04660	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GGC03_RS04695	COG1653	transport
GGC03_RS04700	COG1175	transmembrane transport
GGC03_RS04710	COG3842	ATPase activity
GGC03_RS04715	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GGC03_RS04720	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
GGC03_RS04725	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GGC03_RS04735	COG2204	response regulator
GGC03_RS04760	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GGC03_RS04765	COG0776	regulation of translation
GGC03_RS04770	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GGC03_RS04775	COG1555	photosystem II stabilization
GGC03_RS04785	COG0539	negative regulation of cytoplasmic translation
GGC03_RS04795	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
GGC03_RS04800	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
GGC03_RS04805	COG0284	orotidine-5'-phosphate decarboxylase activity
GGC03_RS04840	COG4120	Belongs to the binding-protein-dependent transport system permease family
GGC03_RS04850	COG3706	GGDEF domain
GGC03_RS04855	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GGC03_RS04875	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GGC03_RS04880	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GGC03_RS04890	COG0252	asparaginase activity
GGC03_RS04895	COG0616	signal peptide processing
GGC03_RS04900	COG1902	pentaerythritol trinitrate reductase activity
GGC03_RS04900	COG0446	pyridine nucleotide-disulphide oxidoreductase
GGC03_RS04905	COG0788	formyltetrahydrofolate deformylase activity
GGC03_RS04915	COG1199	ATP-dependent helicase activity
GGC03_RS04920	COG1214	PFAM Peptidase M22, glycoprotease
GGC03_RS04935	COG2267	carboxylic ester hydrolase activity
GGC03_RS04940	COG0318	PFAM AMP-dependent synthetase and ligase
GGC03_RS04945	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
GGC03_RS04950	COG0659	secondary active sulfate transmembrane transporter activity
GGC03_RS04955	COG1530	ribonuclease E activity
GGC03_RS04960	COG0564	pseudouridine synthase activity
GGC03_RS04965	COG0424	maF-like protein
GGC03_RS04970	COG1399	metal-binding, possibly nucleic acid-binding protein
GGC03_RS04975	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GGC03_RS04985	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GGC03_RS05010	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GGC03_RS05015	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GGC03_RS05020	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GGC03_RS05025	COG0470	DNA polymerase III
GGC03_RS05030	COG0084	hydrolase, TatD family'
GGC03_RS05035	COG1263	PTS System
GGC03_RS05035	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GGC03_RS05055	COG0733	neurotransmitter:sodium symporter activity
GGC03_RS05070	COG4667	esterase of the alpha-beta hydrolase superfamily
GGC03_RS05075	COG0469	pyruvate kinase activity
GGC03_RS05080	COG1940	carbohydrate kinase activity
GGC03_RS05085	COG0784	Response regulator, receiver
GGC03_RS05085	COG0835	chemotaxis
GGC03_RS05105	COG1028	Short-chain dehydrogenase reductase Sdr
GGC03_RS05110	COG0616	signal peptide processing
GGC03_RS05115	COG0513	Belongs to the DEAD box helicase family
GGC03_RS05130	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GGC03_RS05135	COG0232	Belongs to the dGTPase family. Type 2 subfamily
GGC03_RS05145	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
GGC03_RS05150	COG0436	Aminotransferase
GGC03_RS05155	COG1169	isochorismate synthase
GGC03_RS05160	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
GGC03_RS05165	COG0596	Alpha beta hydrolase
GGC03_RS05185	COG2855	membrane
GGC03_RS05190	COG0477	Major facilitator Superfamily
GGC03_RS05215	COG1522	sequence-specific DNA binding
GGC03_RS05230	COG1946	Acyl-CoA thioesterase
GGC03_RS05235	COG3126	Type III secretion system lipoprotein chaperone (YscW)
GGC03_RS05250	COG3706	GGDEF domain
GGC03_RS05295	COG1414	Transcriptional regulator
GGC03_RS05300	COG0280	phosphate acetyltransferase
GGC03_RS05305	COG0730	response to heat
GGC03_RS05325	COG2855	membrane
GGC03_RS05340	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GGC03_RS05345	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GGC03_RS05350	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
GGC03_RS05355	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
GGC03_RS05355	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GGC03_RS05370	COG1472	Belongs to the glycosyl hydrolase 3 family
GGC03_RS05375	COG3876	Protein conserved in bacteria
GGC03_RS05385	COG1215	transferase activity, transferring glycosyl groups
GGC03_RS05405	COG1770	oligopeptidase
GGC03_RS05415	COG3227	Zinc metalloprotease (Elastase)
GGC03_RS05425	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GGC03_RS05445	COG0577	efflux transmembrane transporter activity
GGC03_RS05445	COG1136	(ABC) transporter
GGC03_RS05465	COG0330	HflC and HflK could
GGC03_RS05475	COG0840	transmembrane signaling receptor activity
GGC03_RS05480	COG1404	Belongs to the peptidase S8 family
GGC03_RS05510	COG2067	long-chain fatty acid transport protein
GGC03_RS05525	COG0601	transmembrane transport
GGC03_RS05530	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GGC03_RS05535	COG0444	Belongs to the ABC transporter superfamily
GGC03_RS05545	COG0435	Glutathione S-transferase
GGC03_RS05555	COG0857	belongs to the CobB CobQ family
GGC03_RS05555	COG0280	phosphate acetyltransferase
GGC03_RS05560	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GGC03_RS05565	COG3092	negative regulation of chromosome organization
GGC03_RS05570	COG0686	Belongs to the AlaDH PNT family
GGC03_RS05580	COG1674	ftsk spoiiie
GGC03_RS05590	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GGC03_RS05595	COG2186	Transcriptional regulator
GGC03_RS05610	COG0537	adenosine 5'-monophosphoramidase activity
GGC03_RS05640	COG1252	NADH dehydrogenase
GGC03_RS05665	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GGC03_RS05675	COG4591	ABC-type transport system involved in lipoprotein release permease component
GGC03_RS05680	COG1136	(ABC) transporter
GGC03_RS05685	COG4591	ABC-type transport system involved in lipoprotein release permease component
GGC03_RS05695	COG0658	competence protein
GGC03_RS05695	COG2333	competence protein COMEC
GGC03_RS05700	COG1132	(ABC) transporter
GGC03_RS05710	COG2835	tetraacyldisaccharide 4'-kinase activity
GGC03_RS05715	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
GGC03_RS05720	COG2719	SpoVR family
GGC03_RS05725	COG2718	Belongs to the UPF0229 family
GGC03_RS05730	COG2766	serine protein kinase
GGC03_RS05735	COG3713	MltA-interacting MipA family protein
GGC03_RS05740	COG3013	Belongs to the UPF0304 family
GGC03_RS05750	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GGC03_RS05765	COG1882	Formate acetyltransferase
GGC03_RS05800	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GGC03_RS05935	COG3772	lysozyme
GGC03_RS05950	COG4695	Portal protein
GGC03_RS05990	COG4386	tail sheath protein
GGC03_RS06025	COG3646	Phage regulatory protein
GGC03_RS06045	COG1012	belongs to the aldehyde dehydrogenase family
GGC03_RS06045	COG1454	alcohol dehydrogenase
GGC03_RS06050	COG1737	Transcriptional regulator
GGC03_RS06055	COG0076	glutamate decarboxylase activity
GGC03_RS06065	COG2431	L-lysine efflux transmembrane transporter activity
GGC03_RS06075	COG3070	regulator of competence-specific genes
GGC03_RS06090	COG4191	Histidine kinase
GGC03_RS06090	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GGC03_RS06100	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GGC03_RS06110	COG1032	radical SAM domain protein
GGC03_RS06135	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GGC03_RS06140	COG1764	response to oxidative stress
GGC03_RS06145	COG1846	Transcriptional regulator
GGC03_RS06155	COG0583	DNA-binding transcription factor activity
GGC03_RS06165	COG0673	inositol 2-dehydrogenase activity
GGC03_RS06170	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GGC03_RS06190	COG0840	transmembrane signaling receptor activity
GGC03_RS06195	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GGC03_RS06210	COG3152	Membrane
GGC03_RS06255	COG1858	cytochrome C peroxidase
GGC03_RS06270	COG0443	Heat shock 70 kDa protein
GGC03_RS06320	COG1643	Atp-dependent helicase
GGC03_RS06330	COG1301	dicarboxylic acid transport
GGC03_RS06335	COG0159	tryptophan synthase activity
GGC03_RS06345	COG0135	phosphoribosylanthranilate isomerase activity
GGC03_RS06345	COG0134	indole-3-glycerol-phosphate synthase activity
GGC03_RS06350	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GGC03_RS06355	COG0512	Glutamine amidotransferase of anthranilate synthase
GGC03_RS06360	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GGC03_RS06370	COG0613	PHP domain protein
GGC03_RS06375	COG0009	L-threonylcarbamoyladenylate synthase
GGC03_RS06390	COG1187	pseudouridine synthase activity
GGC03_RS06395	COG0384	phenazine biosynthesis protein PhzF
GGC03_RS06405	COG2814	Major facilitator Superfamily
GGC03_RS06410	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GGC03_RS06415	COG4988	ABC transporter
GGC03_RS06420	COG0492	ferredoxin-NADP+ reductase activity
GGC03_RS06435	COG2175	clavaminate synthase activity
GGC03_RS06450	COG0612	Peptidase, M16
GGC03_RS06460	COG2949	membrane
GGC03_RS06470	COG0281	malic enzyme
GGC03_RS06475	COG1643	Atp-dependent helicase
GGC03_RS06490	COG1448	Aminotransferase
GGC03_RS06495	COG3437	response regulator, receiver
GGC03_RS06495	COG2770	Histidine kinase
GGC03_RS06505	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GGC03_RS06520	COG0017	Asparaginyl-tRNA synthetase
GGC03_RS06535	COG0814	amino acid
GGC03_RS06545	COG1760	l-serine dehydratase
GGC03_RS06550	COG0814	amino acid
GGC03_RS06555	COG0494	nUDIX hydrolase
GGC03_RS06565	COG0784	Response regulator, receiver
GGC03_RS06565	COG2205	protein histidine kinase activity
GGC03_RS06585	COG3106	COG3106 Predicted ATPase
GGC03_RS06600	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GGC03_RS06620	COG3706	GGDEF domain
GGC03_RS06625	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GGC03_RS06650	COG2989	Protein conserved in bacteria
GGC03_RS06655	COG3108	Peptidase M15
GGC03_RS06660	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GGC03_RS06675	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
GGC03_RS06710	COG4667	esterase of the alpha-beta hydrolase superfamily
GGC03_RS06715	COG0783	Belongs to the Dps family
GGC03_RS06725	COG0531	amino acid
GGC03_RS06730	COG2962	Rard protein
GGC03_RS06805	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GGC03_RS06945	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GGC03_RS06985	COG0546	phosphoglycolate phosphatase activity
GGC03_RS06990	COG4628	conserved protein (DUF2132)
GGC03_RS07000	COG0456	acetyltransferase
GGC03_RS07010	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GGC03_RS07020	COG0730	response to heat
GGC03_RS07030	COG1028	Short-chain dehydrogenase reductase Sdr
GGC03_RS07040	COG2824	Alkylphosphonate utilization operon protein PhnA
GGC03_RS07055	COG0456	acetyltransferase
GGC03_RS07075	COG3040	lipid binding
GGC03_RS07090	COG3122	Protein conserved in bacteria
GGC03_RS07145	COG0454	-acetyltransferase
GGC03_RS07150	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GGC03_RS07175	COG0456	acetyltransferase
GGC03_RS07195	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GGC03_RS07210	COG2195	Cleaves the N-terminal amino acid of tripeptides
GGC03_RS07220	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
GGC03_RS07230	COG0625	glutathione transferase activity
GGC03_RS07245	COG2885	chlorophyll binding
GGC03_RS07260	COG0277	FAD linked oxidase domain protein
GGC03_RS07260	COG0247	lactate metabolic process
GGC03_RS07275	COG2986	histidine ammonia-lyase
GGC03_RS07285	COG0010	Belongs to the arginase family
GGC03_RS07290	COG1228	amidohydrolase
GGC03_RS07295	COG2188	Transcriptional regulator
GGC03_RS07300	COG4326	sporulation control protein
GGC03_RS07320	COG0500	methyltransferase
GGC03_RS07325	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
GGC03_RS07335	COG0295	cytidine deaminase activity
GGC03_RS07340	COG1346	cytolysis
GGC03_RS07345	COG1380	Effector of murein hydrolase LrgA
GGC03_RS07350	COG2925	Exonuclease
GGC03_RS07355	COG1823	symporter activity
GGC03_RS07360	COG0702	epimerase
GGC03_RS07365	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GGC03_RS07370	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
GGC03_RS07375	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
GGC03_RS07385	COG0406	alpha-ribazole phosphatase activity
GGC03_RS07405	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
GGC03_RS07430	COG2814	Major facilitator Superfamily
GGC03_RS07440	COG1119	ATPase activity
GGC03_RS07450	COG0784	Response regulator, receiver
GGC03_RS07450	COG5002	protein histidine kinase activity
GGC03_RS07460	COG1451	nucleotide metabolic process
GGC03_RS07475	COG3063	Type IV pilus biogenesis stability protein PilW
GGC03_RS07480	COG0508	dehydrogenase complex catalyzes the overall conversion of
GGC03_RS07480	COG0596	Alpha beta hydrolase
GGC03_RS07485	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
GGC03_RS07500	COG4943	cyclic-guanylate-specific phosphodiesterase activity
GGC03_RS07515	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GGC03_RS07540	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GGC03_RS07545	COG0515	serine threonine protein kinase
GGC03_RS07660	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
GGC03_RS07665	COG0372	Belongs to the citrate synthase family
GGC03_RS07675	COG2828	Protein conserved in bacteria
GGC03_RS07695	COG0561	phosphatase activity
GGC03_RS07700	COG0602	queuosine metabolic process
GGC03_RS07735	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GGC03_RS07740	COG0840	transmembrane signaling receptor activity
GGC03_RS07745	COG1254	Belongs to the acylphosphatase family
GGC03_RS07750	COG2920	part of a sulfur-relay system
GGC03_RS07755	COG0670	Belongs to the BI1 family
GGC03_RS07760	COG1126	abc transporter atp-binding protein
GGC03_RS07765	COG0765	amino acid transport
GGC03_RS07770	COG4597	amino acid ABC transporter
GGC03_RS07775	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GGC03_RS07790	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GGC03_RS07815	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GGC03_RS07815	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
GGC03_RS07820	COG3008	intermembrane lipid transfer
GGC03_RS07825	COG2995	paraquat-inducible protein a
GGC03_RS07830	COG1132	(ABC) transporter
GGC03_RS07835	COG1956	GAF domain-containing protein
GGC03_RS07840	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
GGC03_RS07855	COG0308	aminopeptidase N
GGC03_RS07870	COG0167	dihydroorotate dehydrogenase activity
GGC03_RS07880	COG0116	Belongs to the methyltransferase superfamily
GGC03_RS07880	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GGC03_RS07890	COG0488	(ABC) transporter
GGC03_RS07905	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GGC03_RS07910	COG1067	ATP-dependent peptidase activity
GGC03_RS07965	COG0789	Transcriptional regulator
GGC03_RS07995	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GGC03_RS08015	COG0840	transmembrane signaling receptor activity
GGC03_RS08165	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GGC03_RS08195	COG1132	(ABC) transporter
GGC03_RS08275	COG2197	response regulator
GGC03_RS08310	COG3278	Belongs to the heme-copper respiratory oxidase family
GGC03_RS08325	COG2010	Cytochrome c
GGC03_RS08335	COG2217	Heavy metal translocating P-type atpase
GGC03_RS08350	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GGC03_RS08355	COG0589	response to stress
GGC03_RS08380	COG3842	ATPase activity
GGC03_RS08390	COG1177	transmembrane transport
GGC03_RS08395	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GGC03_RS08400	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GGC03_RS08405	COG2199	diguanylate cyclase activity
GGC03_RS08410	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GGC03_RS08415	COG0004	ammonium transporteR
GGC03_RS08430	COG0437	4 iron, 4 sulfur cluster binding
GGC03_RS08435	COG3383	formate dehydrogenase (NAD+) activity
GGC03_RS08435	COG0243	molybdopterin cofactor binding
GGC03_RS08465	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GGC03_RS08475	COG3038	cytochrome b561
GGC03_RS08500	COG0583	DNA-binding transcription factor activity
GGC03_RS08510	COG0583	DNA-binding transcription factor activity
GGC03_RS08515	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
GGC03_RS08535	COG0069	glutamate synthase activity
GGC03_RS08540	COG1028	Short-chain dehydrogenase reductase Sdr
GGC03_RS08555	COG0488	(ABC) transporter
GGC03_RS08565	COG1595	DNA-templated transcription, initiation
GGC03_RS08580	COG3852	Histidine kinase
GGC03_RS08595	COG4662	Binding-protein-dependent transport system inner membrane component
GGC03_RS08600	COG3842	ATPase activity
GGC03_RS08605	COG0746	molybdenum cofactor guanylyltransferase activity
GGC03_RS08610	COG0303	'Molybdopterin
GGC03_RS08640	COG1940	carbohydrate kinase activity
GGC03_RS08645	COG3148	PFAM DTW domain containing protein
GGC03_RS08655	COG0840	transmembrane signaling receptor activity
GGC03_RS08660	COG0791	NLP P60 protein
GGC03_RS08670	COG3001	Fructosamine kinase
GGC03_RS08680	COG0307	riboflavin synthase, alpha
GGC03_RS08685	COG0534	Mate efflux family protein
GGC03_RS08730	COG2204	response regulator
GGC03_RS08740	COG0438	transferase activity, transferring glycosyl groups
GGC03_RS08775	COG0297	glycogen (starch) synthase activity
GGC03_RS08785	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GGC03_RS08825	COG4774	siderophore transport
GGC03_RS08845	COG4615	Cyclic peptide transporter
GGC03_RS08855	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GGC03_RS08860	COG1120	ATPase activity
GGC03_RS08865	COG2977	Belongs to the P-Pant transferase superfamily
GGC03_RS08870	COG1929	Belongs to the glycerate kinase type-1 family
GGC03_RS08875	COG3835	regulator
GGC03_RS08885	COG2814	Major facilitator Superfamily
GGC03_RS08895	COG1288	antiporter activity
GGC03_RS08905	COG2186	Transcriptional regulator
GGC03_RS08915	COG3713	MltA-interacting MipA family protein
GGC03_RS08925	COG0745	RESPONSE REGULATOR receiver
GGC03_RS08935	COG0583	DNA-binding transcription factor activity
GGC03_RS08955	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GGC03_RS08975	COG2116	formate transmembrane transporter activity
GGC03_RS08985	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GGC03_RS08995	COG2199	diguanylate cyclase activity
GGC03_RS09015	COG4565	transcriptional regulatory protein
GGC03_RS09020	COG3290	protein histidine kinase activity
GGC03_RS09040	COG0848	biopolymer transport protein
GGC03_RS09045	COG0811	peptide transport
GGC03_RS09050	COG0811	peptide transport
GGC03_RS09060	COG4774	siderophore transport
GGC03_RS09065	COG2205	protein histidine kinase activity
GGC03_RS09070	COG0745	RESPONSE REGULATOR receiver
GGC03_RS09075	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GGC03_RS09115	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GGC03_RS09120	COG1328	CTP reductase activity
GGC03_RS09125	COG0840	transmembrane signaling receptor activity
GGC03_RS09135	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GGC03_RS09140	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GGC03_RS09145	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GGC03_RS09150	COG0633	Ferredoxin
GGC03_RS09175	COG0019	diaminopimelate decarboxylase activity
GGC03_RS09215	COG0577	efflux transmembrane transporter activity
GGC03_RS09220	COG1136	(ABC) transporter
GGC03_RS09225	COG0534	Mate efflux family protein
GGC03_RS09230	COG0702	epimerase
GGC03_RS09240	COG2814	Major facilitator Superfamily
GGC03_RS09250	COG1061	Type III restriction enzyme res subunit
GGC03_RS09290	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GGC03_RS09295	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GGC03_RS09315	COG0463	Glycosyl transferase, family 2
GGC03_RS09340	COG0455	bacterial-type flagellum organization
GGC03_RS09355	COG2188	Transcriptional regulator
GGC03_RS09360	COG1263	PTS System
GGC03_RS09360	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GGC03_RS09365	COG1621	beta-fructofuranosidase activity
GGC03_RS09375	COG0583	DNA-binding transcription factor activity
GGC03_RS09380	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GGC03_RS09415	COG4221	oxidoreductase activity
GGC03_RS09445	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GGC03_RS09450	COG0307	riboflavin synthase, alpha
GGC03_RS09500	COG0242	peptide deformylase activity
GGC03_RS09505	COG0519	Catalyzes the synthesis of GMP from XMP
GGC03_RS09520	COG4580	involved in the transport of maltose and maltodextrins
GGC03_RS09525	COG0778	Nitroreductase
GGC03_RS09580	COG5001	Diguanylate cyclase
GGC03_RS09580	COG3300	MHYT domain
GGC03_RS09605	COG1115	amino acid carrier protein
GGC03_RS09610	COG1280	lysine exporter protein (LysE YggA)
GGC03_RS09615	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
GGC03_RS09620	COG0352	thiamine-phosphate diphosphorylase activity
GGC03_RS09625	COG0583	DNA-binding transcription factor activity
GGC03_RS09650	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GGC03_RS09660	COG1012	belongs to the aldehyde dehydrogenase family
GGC03_RS09670	COG0583	DNA-binding transcription factor activity
GGC03_RS09710	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GGC03_RS09720	COG1609	Transcriptional regulator
GGC03_RS09735	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GGC03_RS09740	COG1609	Transcriptional regulator
GGC03_RS09750	COG0642	Histidine kinase
GGC03_RS09755	COG0745	RESPONSE REGULATOR receiver
GGC03_RS09775	COG1858	cytochrome C peroxidase
GGC03_RS09785	COG0784	Response regulator, receiver
GGC03_RS09785	COG2205	protein histidine kinase activity
GGC03_RS09790	COG0488	(ABC) transporter
GGC03_RS09795	COG3437	response regulator, receiver
GGC03_RS09805	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GGC03_RS09815	COG2223	nitrite transmembrane transporter activity
GGC03_RS09820	COG1216	Glycosyl transferase, family 2
GGC03_RS09830	COG0673	inositol 2-dehydrogenase activity
GGC03_RS09835	COG3718	enzyme involved in inositol metabolism
GGC03_RS09860	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GGC03_RS09865	COG0673	inositol 2-dehydrogenase activity
GGC03_RS09870	COG3962	Belongs to the TPP enzyme family
GGC03_RS09880	COG2814	Major facilitator Superfamily
GGC03_RS09880	COG0477	Major facilitator Superfamily
GGC03_RS09900	COG0183	Belongs to the thiolase family
GGC03_RS09905	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GGC03_RS09945	COG3962	Belongs to the TPP enzyme family
GGC03_RS09950	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GGC03_RS09960	COG1129	ABC transporter
GGC03_RS09965	COG4211	Belongs to the binding-protein-dependent transport system permease family
GGC03_RS09975	COG0277	FAD linked oxidase domain protein
GGC03_RS09985	COG0583	DNA-binding transcription factor activity
GGC03_RS10005	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GGC03_RS10010	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
GGC03_RS10030	COG1621	beta-fructofuranosidase activity
GGC03_RS10045	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GGC03_RS10045	COG1263	PTS System
GGC03_RS10055	COG1335	isochorismatase
GGC03_RS10060	COG1741	Belongs to the pirin family
GGC03_RS10105	COG4974	Belongs to the 'phage' integrase family
GGC03_RS10115	COG1733	regulation of RNA biosynthetic process
GGC03_RS10125	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
GGC03_RS10145	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GGC03_RS10150	COG0072	phenylalanine-tRNA ligase activity
GGC03_RS10150	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GGC03_RS10160	COG3706	GGDEF domain
GGC03_RS10185	COG2133	pyrroloquinoline quinone binding
GGC03_RS10195	COG1902	pentaerythritol trinitrate reductase activity
GGC03_RS10225	COG0322	excinuclease ABC activity
GGC03_RS10230	COG2197	response regulator
GGC03_RS10245	COG0417	DNA replication proofreading
GGC03_RS10260	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GGC03_RS10270	COG0776	regulation of translation
GGC03_RS10305	COG2350	Protein conserved in bacteria
GGC03_RS10320	COG3313	Fe-S protein
GGC03_RS10330	COG4134	Bacterial extracellular solute-binding protein
GGC03_RS10335	COG4135	transport system, permease component
GGC03_RS10340	COG4136	ATPase activity
GGC03_RS10345	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GGC03_RS10350	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GGC03_RS10355	COG0564	pseudouridine synthase activity
GGC03_RS10360	COG0733	neurotransmitter:sodium symporter activity
GGC03_RS10370	COG0626	cystathionine gamma-synthase activity
GGC03_RS10375	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
GGC03_RS10380	COG5380	lipid catabolic process
GGC03_RS10385	COG2818	Glycosylase
GGC03_RS10400	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GGC03_RS10405	COG1983	PspC domain protein
GGC03_RS10415	COG1842	Phage shock protein A
GGC03_RS10420	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GGC03_RS10435	COG4171	peptide transport system, permease
GGC03_RS10445	COG4172	Belongs to the ABC transporter superfamily
GGC03_RS10460	COG1227	inorganic diphosphatase activity
GGC03_RS10470	COG0217	transcriptional regulatory protein
GGC03_RS10475	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GGC03_RS10475	COG0140	phosphoribosyl-ATP diphosphatase activity
GGC03_RS10485	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GGC03_RS10490	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GGC03_RS10495	COG0131	Imidazoleglycerol-phosphate dehydratase
GGC03_RS10495	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GGC03_RS10505	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GGC03_RS10515	COG1757	Na H antiporter
GGC03_RS10525	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GGC03_RS10535	COG0482	sulfurtransferase activity
GGC03_RS10545	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GGC03_RS10555	COG2268	Band 7 protein
GGC03_RS10565	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GGC03_RS10580	COG1028	Short-chain dehydrogenase reductase Sdr
GGC03_RS10590	COG0501	Belongs to the peptidase M48B family
GGC03_RS10595	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
GGC03_RS10600	COG1073	alpha beta
GGC03_RS10600	COG2226	methyltransferase
GGC03_RS10605	COG0156	8-amino-7-oxononanoate synthase activity
GGC03_RS10615	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GGC03_RS10630	COG1199	ATP-dependent helicase activity
GGC03_RS10635	COG0730	response to heat
GGC03_RS10650	COG2850	peptidyl-arginine hydroxylation
GGC03_RS10655	COG0840	transmembrane signaling receptor activity
GGC03_RS10660	COG0708	Exodeoxyribonuclease III
GGC03_RS10665	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GGC03_RS10670	COG1960	acyl-CoA dehydrogenase activity
GGC03_RS10685	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GGC03_RS10690	COG0463	Glycosyl transferase, family 2
GGC03_RS10695	COG0745	RESPONSE REGULATOR receiver
GGC03_RS10700	COG3850	Histidine kinase
GGC03_RS10700	COG5002	protein histidine kinase activity
GGC03_RS10715	COG1940	carbohydrate kinase activity
GGC03_RS10730	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GGC03_RS10735	COG1881	PFAM PEBP family protein
GGC03_RS10740	COG1902	pentaerythritol trinitrate reductase activity
GGC03_RS10760	COG5002	protein histidine kinase activity
GGC03_RS10760	COG0784	Response regulator, receiver
GGC03_RS10775	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
GGC03_RS10780	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GGC03_RS10785	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
GGC03_RS10790	COG2885	chlorophyll binding
GGC03_RS10795	COG0823	Involved in the tonB-independent uptake of proteins
GGC03_RS10810	COG0811	peptide transport
GGC03_RS10815	COG0824	Thioesterase
GGC03_RS10825	COG4890	Cyd operon protein YbgT
GGC03_RS10830	COG1294	oxidase, subunit
GGC03_RS10835	COG1271	oxidase subunit
GGC03_RS10840	COG2255	four-way junction helicase activity
GGC03_RS10845	COG0632	four-way junction helicase activity
GGC03_RS10850	COG0840	transmembrane signaling receptor activity
GGC03_RS10855	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
GGC03_RS10875	COG4221	oxidoreductase activity
GGC03_RS10890	COG0243	molybdopterin cofactor binding
GGC03_RS10895	COG3005	denitrification pathway
GGC03_RS10900	COG4459	periplasmic nitrate reductase
GGC03_RS10905	COG0390	transport system, permease component
GGC03_RS10910	COG2116	formate transmembrane transporter activity
GGC03_RS10935	COG0542	response to heat
GGC03_RS10940	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
GGC03_RS10945	COG1278	Cold shock
GGC03_RS10955	COG1187	pseudouridine synthase activity
GGC03_RS10965	COG1801	Protein of unknown function DUF72
GGC03_RS10975	COG0500	methyltransferase
GGC03_RS10980	COG4067	protein conserved in archaea
GGC03_RS10980	COG0189	ligase activity
GGC03_RS11010	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
GGC03_RS11015	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
GGC03_RS11025	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GGC03_RS11030	COG1434	Gram-negative-bacterium-type cell wall biogenesis
GGC03_RS11035	COG0745	RESPONSE REGULATOR receiver
GGC03_RS11050	COG3070	regulator of competence-specific genes
GGC03_RS11070	COG0297	glycogen (starch) synthase activity
GGC03_RS11075	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GGC03_RS11080	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GGC03_RS11090	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GGC03_RS11100	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
GGC03_RS11105	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
GGC03_RS11110	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GGC03_RS11115	COG1435	thymidine kinase activity
GGC03_RS11120	COG0215	cysteine-tRNA ligase activity
GGC03_RS11125	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GGC03_RS11130	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GGC03_RS11135	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
GGC03_RS11140	COG3012	SEC-C Motif Domain Protein
GGC03_RS11145	COG3139	Protein of unknown function (DUF1315)
GGC03_RS11155	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GGC03_RS11170	COG0840	transmembrane signaling receptor activity
GGC03_RS11175	COG2226	methyltransferase
GGC03_RS11190	COG1785	Belongs to the alkaline phosphatase family
GGC03_RS11210	COG0668	transmembrane transport
GGC03_RS11215	COG2983	Belongs to the UPF0260 family
GGC03_RS11230	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GGC03_RS11235	COG0583	DNA-binding transcription factor activity
GGC03_RS11240	COG2951	lytic endotransglycosylase activity
GGC03_RS11245	COG3100	YcgL domain-containing protein
GGC03_RS11250	COG0850	regulation of cytokinetic process
GGC03_RS11255	COG2894	cell division
GGC03_RS11260	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
GGC03_RS11265	COG1012	belongs to the aldehyde dehydrogenase family
GGC03_RS11265	COG1454	alcohol dehydrogenase
GGC03_RS11270	COG2095	MarC family integral membrane protein
GGC03_RS11275	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GGC03_RS11280	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GGC03_RS11285	COG1757	Na H antiporter
GGC03_RS11305	COG3081	Nucleoid-associated protein
GGC03_RS11310	COG3082	Protein of unknown function (DUF1414)
GGC03_RS11315	COG3083	sulfuric ester hydrolase activity
GGC03_RS11375	COG0123	including yeast histone deacetylase and acetoin utilization protein
GGC03_RS11385	COG1881	PFAM PEBP family protein
GGC03_RS11395	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GGC03_RS11400	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
GGC03_RS11420	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GGC03_RS11425	COG0302	gtp cyclohydrolase
GGC03_RS11425	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GGC03_RS11430	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GGC03_RS11435	COG0302	gtp cyclohydrolase
GGC03_RS11445	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
GGC03_RS11450	COG0110	maltose O-acetyltransferase activity
GGC03_RS11505	COG2982	Protein involved in outer membrane biogenesis
GGC03_RS11510	COG0572	uridine kinase
GGC03_RS11515	COG0489	protein tyrosine kinase activity
GGC03_RS11560	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GGC03_RS11560	COG0617	tRNA 3'-terminal CCA addition
GGC03_RS11560	COG0517	IMP dehydrogenase activity
GGC03_RS11570	COG3706	GGDEF domain
GGC03_RS11575	COG0314	molybdopterin synthase activity
GGC03_RS11580	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
GGC03_RS11590	COG0521	Mo-molybdopterin cofactor biosynthetic process
GGC03_RS11595	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GGC03_RS11600	COG0391	Required for morphogenesis under gluconeogenic growth conditions
GGC03_RS11605	COG2198	Histidine kinase
GGC03_RS11615	COG0556	nucleotide-excision repair
GGC03_RS11635	COG0739	heme binding
GGC03_RS11680	COG2885	chlorophyll binding
GGC03_RS11700	COG1987	bacterial-type flagellum assembly
GGC03_RS11725	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GGC03_RS11730	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
GGC03_RS11735	COG1516	flagellar protein fliS
GGC03_RS11750	COG1580	Controls the rotational direction of flagella during chemotaxis
GGC03_RS11755	COG1191	sigma factor activity
GGC03_RS11760	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GGC03_RS11765	COG1360	Flagellar Motor Protein
GGC03_RS11795	COG1706	bacterial-type flagellum-dependent cell motility
GGC03_RS11800	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
GGC03_RS11805	COG4786	Flagellar basal body rod
GGC03_RS11810	COG4787	bacterial-type flagellum-dependent cell motility
GGC03_RS11815	COG1749	Flagellar hook protein flgE
GGC03_RS11825	COG1558	bacterial-type flagellum-dependent cell motility
GGC03_RS11830	COG1815	bacterial-type flagellum-dependent cell motility
GGC03_RS11850	COG0741	lytic transglycosylase activity
GGC03_RS11850	COG1388	LysM domain
GGC03_RS11855	COG4657	Part of a membrane complex involved in electron transport
GGC03_RS11865	COG4656	Part of a membrane complex involved in electron transport
GGC03_RS11870	COG4658	electron transport chain
GGC03_RS11875	COG4659	FMN binding
GGC03_RS11880	COG4660	Part of a membrane complex involved in electron transport
GGC03_RS11885	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GGC03_RS11890	COG0346	lactoylglutathione lyase activity
GGC03_RS11910	COG2056	Na+-H+ antiporter family
GGC03_RS11915	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
GGC03_RS11925	COG2716	regulation of RNA biosynthetic process
GGC03_RS11930	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GGC03_RS11950	COG4783	chaperone-mediated protein folding
GGC03_RS11955	COG1393	Belongs to the ArsC family
GGC03_RS11980	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GGC03_RS11990	COG2877	3-deoxy-8-phosphooctulonate synthase activity
GGC03_RS11995	COG2912	Transglutaminase-like superfamily
GGC03_RS12005	COG2890	protein-(glutamine-N5) methyltransferase activity
GGC03_RS12025	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GGC03_RS12030	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GGC03_RS12040	COG0012	GTP binding
GGC03_RS12160	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GGC03_RS12170	COG3951	Flagellar rod assembly protein muramidase FlgJ
GGC03_RS12170	COG1705	Flagellar rod assembly protein muramidase FlgJ
GGC03_RS12175	COG1706	bacterial-type flagellum-dependent cell motility
GGC03_RS12180	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
GGC03_RS12190	COG4787	bacterial-type flagellum-dependent cell motility
GGC03_RS12210	COG1815	bacterial-type flagellum-dependent cell motility
GGC03_RS12215	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GGC03_RS12220	COG0835	chemotaxis
GGC03_RS12220	COG0784	Response regulator, receiver
GGC03_RS12230	COG2747	anti-sigma28 factor FlgM
GGC03_RS12270	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GGC03_RS12280	COG2194	sulfuric ester hydrolase activity
GGC03_RS12300	COG2885	chlorophyll binding
GGC03_RS12300	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
GGC03_RS12320	COG2608	mercury ion transmembrane transporter activity
GGC03_RS12320	COG2217	Heavy metal translocating P-type atpase
GGC03_RS12340	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
GGC03_RS12350	COG0326	Molecular chaperone. Has ATPase activity
GGC03_RS12355	COG3710	Transcriptional regulator
GGC03_RS12375	COG0622	Phosphoesterase
GGC03_RS12400	COG1090	epimerase
GGC03_RS12405	COG0300	oxidoreductase activity
GGC03_RS12415	COG3118	belongs to the thioredoxin family
GGC03_RS12420	COG0330	HflC and HflK could
GGC03_RS12440	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GGC03_RS12445	COG3115	cell septum assembly
GGC03_RS12450	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
GGC03_RS12455	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GGC03_RS12460	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GGC03_RS12465	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GGC03_RS12470	COG2190	(PTS) system
GGC03_RS12475	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GGC03_RS12485	COG1702	phosphate starvation-inducible protein PhoH
GGC03_RS12490	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GGC03_RS12495	COG4535	Mg2 and Co2 transporter CorC
GGC03_RS12500	COG0815	Transfers the fatty acyl group on membrane lipoproteins
GGC03_RS12505	COG2888	peptidyl-tyrosine sulfation
GGC03_RS12510	COG0495	leucyl-tRNA aminoacylation
GGC03_RS12515	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
GGC03_RS12520	COG1466	dna polymerase III delta subunit
GGC03_RS12525	COG0799	negative regulation of ribosome biogenesis
GGC03_RS12530	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GGC03_RS12535	COG0768	penicillin binding
GGC03_RS12540	COG0772	Belongs to the SEDS family
GGC03_RS12545	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GGC03_RS12550	COG1686	Belongs to the peptidase S11 family
GGC03_RS12555	COG2921	Belongs to the UPF0250 family
GGC03_RS12565	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GGC03_RS12580	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GGC03_RS12590	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GGC03_RS12595	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GGC03_RS12605	COG0366	Alpha amylase catalytic
GGC03_RS12610	COG1263	PTS System
GGC03_RS12610	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GGC03_RS12615	COG1609	Transcriptional regulator
GGC03_RS12625	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GGC03_RS12630	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GGC03_RS12635	COG2011	ABC-type metal ion transport system permease component
GGC03_RS12640	COG1464	Belongs to the NlpA lipoprotein family
GGC03_RS12650	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
GGC03_RS12660	COG0254	rRNA binding
GGC03_RS12665	COG1720	tRNA m6t6A37 methyltransferase activity
GGC03_RS12675	COG0121	glutamine amidotransferase
GGC03_RS12680	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
GGC03_RS12685	COG1960	acyl-CoA dehydrogenase activity
GGC03_RS12700	COG0328	RNA-DNA hybrid ribonuclease activity
GGC03_RS12705	COG2226	methyltransferase
GGC03_RS12710	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GGC03_RS12715	COG0741	lytic transglycosylase activity
GGC03_RS12715	COG1388	LysM domain
GGC03_RS12725	COG3021	interspecies interaction between organisms
GGC03_RS12730	COG0347	Belongs to the P(II) protein family
GGC03_RS12745	COG0825	malonyl-CoA metabolic process
GGC03_RS12750	COG0587	DNA-directed DNA polymerase activity
GGC03_RS12755	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GGC03_RS12770	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GGC03_RS12775	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GGC03_RS12780	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
GGC03_RS12785	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GGC03_RS12790	COG0750	zinc metalloprotease
GGC03_RS12800	COG0575	Belongs to the CDS family
GGC03_RS12805	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GGC03_RS12810	COG0233	cytoplasmic translational termination
GGC03_RS12815	COG0528	UMP kinase activity
GGC03_RS12820	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GGC03_RS12825	COG0052	Belongs to the universal ribosomal protein uS2 family
GGC03_RS12845	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GGC03_RS12850	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
GGC03_RS12855	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GGC03_RS12875	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GGC03_RS12875	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GGC03_RS12880	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GGC03_RS12885	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GGC03_RS12890	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GGC03_RS12900	COG1073	alpha beta
GGC03_RS12905	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
GGC03_RS12910	COG2252	PERMEase
GGC03_RS12915	COG2195	Cleaves the N-terminal amino acid of tripeptides
GGC03_RS12920	COG0189	ligase activity
GGC03_RS12920	COG4067	protein conserved in archaea
GGC03_RS12925	COG0189	ligase activity
GGC03_RS12935	COG0733	neurotransmitter:sodium symporter activity
GGC03_RS12950	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GGC03_RS12960	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GGC03_RS12975	COG1477	protein flavinylation
GGC03_RS12980	COG2871	sodium ion transport
GGC03_RS12985	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GGC03_RS13000	COG1805	sodium ion transport
GGC03_RS13005	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GGC03_RS13010	COG0271	Belongs to the BolA IbaG family
GGC03_RS13015	COG2813	Specifically methylates the guanine in position
GGC03_RS13025	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GGC03_RS13040	COG1595	DNA-templated transcription, initiation
GGC03_RS13055	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GGC03_RS13060	COG0693	protein deglycase activity
GGC03_RS13065	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GGC03_RS13070	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GGC03_RS13080	COG0560	Phosphoserine phosphatase
GGC03_RS13090	COG0813	purine-nucleoside phosphorylase activity
GGC03_RS13095	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
GGC03_RS13100	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
GGC03_RS13115	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GGC03_RS13120	COG0084	hydrolase, TatD family'
GGC03_RS13125	COG3022	response to hydroperoxide
GGC03_RS13130	COG1115	amino acid carrier protein
GGC03_RS13160	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GGC03_RS13190	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GGC03_RS13195	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
GGC03_RS13200	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
GGC03_RS13205	COG0583	DNA-binding transcription factor activity
GGC03_RS13210	COG0730	response to heat
GGC03_RS13215	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GGC03_RS13220	COG0505	Belongs to the CarA family
GGC03_RS13230	COG0494	nUDIX hydrolase
GGC03_RS13235	COG0653	protein targeting
GGC03_RS13240	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
GGC03_RS13245	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GGC03_RS13250	COG0849	cell division
GGC03_RS13255	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GGC03_RS13270	COG0772	Belongs to the SEDS family
GGC03_RS13275	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GGC03_RS13285	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GGC03_RS13295	COG0768	penicillin binding
GGC03_RS13300	COG3116	cell division
GGC03_RS13315	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GGC03_RS13320	COG3107	peptidoglycan biosynthetic process
GGC03_RS13330	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
GGC03_RS13340	COG2969	positive regulation of protein catabolic process
GGC03_RS13345	COG0625	glutathione transferase activity
GGC03_RS13350	COG2857	Cytochrome c1
GGC03_RS13355	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GGC03_RS13360	COG0723	plastoquinol--plastocyanin reductase activity
GGC03_RS13375	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
GGC03_RS13380	COG3105	Protein conserved in bacteria
GGC03_RS13385	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GGC03_RS13390	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GGC03_RS13405	COG3150	esterase
GGC03_RS13415	COG3151	Protein conserved in bacteria
GGC03_RS13420	COG0494	nUDIX hydrolase
GGC03_RS13425	COG1538	Outer membrane efflux protein
GGC03_RS13435	COG0784	Response regulator, receiver
GGC03_RS13435	COG5002	protein histidine kinase activity
GGC03_RS13435	COG2198	Histidine kinase
GGC03_RS13440	COG2203	Gaf domain
GGC03_RS13440	COG3706	GGDEF domain
GGC03_RS13440	COG5001	Diguanylate cyclase
GGC03_RS13440	COG4251	negative regulation of phosphorylation
GGC03_RS13445	COG1242	4 iron, 4 sulfur cluster binding
GGC03_RS13450	COG0069	glutamate synthase activity
GGC03_RS13450	COG0070	glutamate synthase
GGC03_RS13450	COG0067	glutamate synthase
GGC03_RS13460	COG0067	glutamate synthase
GGC03_RS13460	COG0070	glutamate synthase
GGC03_RS13460	COG0069	glutamate synthase activity
GGC03_RS13465	COG0493	'glutamate synthase
GGC03_RS13490	COG0195	Participates in both transcription termination and antitermination
GGC03_RS13495	COG0779	Required for maturation of 30S ribosomal subunits
GGC03_RS13510	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GGC03_RS13515	COG3153	acetyltransferase
GGC03_RS13520	COG3154	lipid carrier protein
GGC03_RS13530	COG0826	peptidase U32
GGC03_RS13535	COG0826	peptidase U32
GGC03_RS13540	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GGC03_RS13560	COG0513	Belongs to the DEAD box helicase family
GGC03_RS13590	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GGC03_RS13595	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GGC03_RS13600	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
GGC03_RS13605	COG1534	Rna-binding protein
GGC03_RS13610	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GGC03_RS13615	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GGC03_RS13620	COG2027	D-alanyl-D-alanine carboxypeptidase
GGC03_RS13630	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GGC03_RS13635	COG0739	heme binding
GGC03_RS13650	COG0316	Belongs to the HesB IscA family
GGC03_RS13660	COG0628	permease
GGC03_RS13665	COG2813	Specifically methylates the guanine in position
GGC03_RS13670	COG2205	protein histidine kinase activity
GGC03_RS13670	COG0784	Response regulator, receiver
GGC03_RS13675	COG0747	negative chemotaxis
GGC03_RS13690	COG0444	Belongs to the ABC transporter superfamily
GGC03_RS13695	COG4608	Belongs to the ABC transporter superfamily
GGC03_RS13705	COG2971	BadF BadG BcrA BcrD
GGC03_RS13720	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GGC03_RS13725	COG3842	ATPase activity
GGC03_RS13735	COG1840	ABC-type Fe3 transport system, periplasmic component
GGC03_RS13740	COG0004	ammonium transporteR
GGC03_RS13755	COG1049	propionate catabolic process, 2-methylcitrate cycle
GGC03_RS13760	COG1752	Esterase of the alpha-beta hydrolase superfamily
GGC03_RS13765	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GGC03_RS13770	COG1643	Atp-dependent helicase
GGC03_RS13780	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GGC03_RS13795	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GGC03_RS13800	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GGC03_RS13810	COG0842	Transport permease protein
GGC03_RS13815	COG1131	(ABC) transporter
GGC03_RS13820	COG0659	secondary active sulfate transmembrane transporter activity
GGC03_RS13825	COG0288	reversible hydration of carbon dioxide
GGC03_RS13840	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GGC03_RS13845	COG0508	dehydrogenase complex catalyzes the overall conversion of
GGC03_RS13850	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
GGC03_RS13855	COG2186	Transcriptional regulator
GGC03_RS13860	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GGC03_RS13865	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GGC03_RS13870	COG4974	Belongs to the 'phage' integrase family
GGC03_RS13880	COG3023	N-Acetylmuramoyl-L-alanine amidase
GGC03_RS13885	COG0157	Belongs to the NadC ModD family
GGC03_RS13890	COG4969	Belongs to the N-Me-Phe pilin family
GGC03_RS13895	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GGC03_RS13900	COG1459	type II secretion system
GGC03_RS13910	COG0237	dephospho-CoA kinase activity
GGC03_RS13915	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
GGC03_RS13920	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
GGC03_RS13930	COG0336	Belongs to the RNA methyltransferase TrmD family
GGC03_RS13940	COG0228	four-way junction DNA binding
GGC03_RS13945	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GGC03_RS13950	COG4137	Cytochrome C assembly protein
GGC03_RS13955	COG4536	flavin adenine dinucleotide binding
GGC03_RS13960	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GGC03_RS13975	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
GGC03_RS13980	COG0585	pseudouridine synthase activity
GGC03_RS13990	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GGC03_RS13995	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
GGC03_RS14000	COG1968	undecaprenyl-diphosphatase activity
GGC03_RS14005	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GGC03_RS14010	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GGC03_RS14015	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
GGC03_RS14020	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GGC03_RS14025	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GGC03_RS14030	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GGC03_RS14035	COG1610	YqeY-like protein
GGC03_RS14040	COG0358	DNA primase activity
GGC03_RS14055	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
GGC03_RS14060	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
GGC03_RS14065	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GGC03_RS14070	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
GGC03_RS14075	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GGC03_RS14085	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GGC03_RS14095	COG3610	response to peptide
GGC03_RS14100	COG2966	Psort location CytoplasmicMembrane, score
GGC03_RS14105	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GGC03_RS14115	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GGC03_RS14120	COG0142	geranyltranstransferase activity
GGC03_RS14130	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
GGC03_RS14135	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GGC03_RS14135	COG2213	PTS system mannitol-specific
GGC03_RS14145	COG3722	fumarate hydratase activity
GGC03_RS14150	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GGC03_RS14155	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GGC03_RS14160	COG1349	DNA-binding transcription factor activity
GGC03_RS14165	COG0469	pyruvate kinase activity
GGC03_RS14185	COG0583	DNA-binding transcription factor activity
GGC03_RS14200	COG0668	transmembrane transport
GGC03_RS14205	COG0191	fructose-bisphosphate aldolase activity
GGC03_RS14215	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GGC03_RS14220	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GGC03_RS14225	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GGC03_RS14235	COG3091	SprT-like family
GGC03_RS14240	COG2356	endonuclease I
GGC03_RS14245	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GGC03_RS14250	COG0189	ligase activity
GGC03_RS14255	COG1678	Uncharacterized ACR, COG1678
GGC03_RS14260	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GGC03_RS14275	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GGC03_RS14280	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GGC03_RS14285	COG0762	integral membrane protein
GGC03_RS14405	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GGC03_RS14410	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GGC03_RS14415	COG2066	Belongs to the glutaminase family
GGC03_RS14420	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GGC03_RS14430	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
GGC03_RS14485	COG0312	modulator of DNA gyrase
GGC03_RS14490	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GGC03_RS14495	COG3164	Protein of unknown function
GGC03_RS14505	COG0424	maF-like protein
GGC03_RS14510	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
GGC03_RS14515	COG1792	Involved in formation and maintenance of cell shape
GGC03_RS14520	COG1077	Cell shape determining protein MreB Mrl
GGC03_RS14550	COG2165	general secretion pathway protein
GGC03_RS14555	COG2165	general secretion pathway protein
GGC03_RS14565	COG1459	type II secretion system
GGC03_RS14570	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GGC03_RS14580	COG3267	Type II secretory pathway component ExeA
GGC03_RS14580	COG3409	Peptidoglycan-binding domain 1 protein
GGC03_RS14605	COG2199	diguanylate cyclase activity
GGC03_RS14605	COG2200	EAL domain
GGC03_RS14610	COG0629	single-stranded DNA binding
GGC03_RS14625	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GGC03_RS14635	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GGC03_RS14640	COG0527	aspartate kinase activity
GGC03_RS14645	COG0312	modulator of DNA gyrase
GGC03_RS14650	COG3028	Belongs to the UPF0307 family
GGC03_RS14655	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
GGC03_RS14660	COG1178	ABC-type Fe3 transport system permease component
GGC03_RS14665	COG4143	(ABC) transporter
GGC03_RS14670	COG0163	prenyltransferase activity
GGC03_RS14675	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GGC03_RS14685	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
GGC03_RS14690	COG2105	PFAM AIG2 family protein
GGC03_RS14695	COG2911	Protein conserved in bacteria
GGC03_RS14700	COG0729	surface antigen
GGC03_RS14705	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GGC03_RS14715	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
GGC03_RS14730	COG1136	(ABC) transporter
GGC03_RS14850	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GGC03_RS14855	COG0305	Participates in initiation and elongation during chromosome replication
GGC03_RS14875	COG0360	Binds together with S18 to 16S ribosomal RNA
GGC03_RS14885	COG2906	2 iron, 2 sulfur cluster binding
GGC03_RS14890	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GGC03_RS14895	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GGC03_RS14900	COG0049	tRNA binding
GGC03_RS14910	COG2168	tRNA wobble position uridine thiolation
GGC03_RS14915	COG2923	Belongs to the DsrF TusC family
GGC03_RS14920	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
GGC03_RS14925	COG2964	Protein conserved in bacteria
GGC03_RS14930	COG0545	Peptidyl-prolyl cis-trans isomerase
GGC03_RS14940	COG2900	Belongs to the SlyX family
GGC03_RS14945	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
GGC03_RS14950	COG0330	HflC and HflK could
GGC03_RS14955	COG0330	HflC and HflK could
GGC03_RS14960	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GGC03_RS14975	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GGC03_RS14985	COG0802	atpase or kinase
GGC03_RS14990	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GGC03_RS15035	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
GGC03_RS15040	COG1162	GTPase activity
GGC03_RS15045	COG0688	phosphatidylethanolamine metabolic process
GGC03_RS15050	COG0471	metal ion transport
GGC03_RS15050	COG0490	domain, Protein
GGC03_RS15055	COG0840	transmembrane signaling receptor activity
GGC03_RS15065	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GGC03_RS15070	COG4942	peptidase
GGC03_RS15090	COG2816	NAD+ diphosphatase activity
GGC03_RS15095	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
GGC03_RS15105	COG0085	RNA polymerase activity
GGC03_RS15115	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GGC03_RS15130	COG0250	Participates in transcription elongation, termination and antitermination
GGC03_RS15135	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GGC03_RS15140	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GGC03_RS15165	COG1072	(Pantothenic acid kinase))
GGC03_RS15180	COG0149	triose-phosphate isomerase activity
GGC03_RS15185	COG0534	Mate efflux family protein
GGC03_RS15190	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GGC03_RS15195	COG1575	Belongs to the MenA family. Type 1 subfamily
GGC03_RS15200	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GGC03_RS15205	COG1509	lysine 2,3-aminomutase activity
GGC03_RS15215	COG1285	pathogenesis
GGC03_RS15220	COG0205	6-phosphofructokinase activity
GGC03_RS15230	COG3678	ATP-independent chaperone mediated protein folding
GGC03_RS15235	COG0745	RESPONSE REGULATOR receiver
GGC03_RS15240	COG2205	protein histidine kinase activity
GGC03_RS15245	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GGC03_RS15250	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GGC03_RS15255	COG0180	Tryptophanyl-tRNA synthetase
GGC03_RS15260	COG0546	phosphoglycolate phosphatase activity
GGC03_RS15265	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GGC03_RS15270	COG0338	D12 class N6 adenine-specific DNA methyltransferase
GGC03_RS15280	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GGC03_RS15315	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
GGC03_RS15325	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GGC03_RS15325	COG0678	peroxiredoxin activity
GGC03_RS15335	COG0251	oxidation-reduction process
GGC03_RS15345	COG0165	Argininosuccinate lyase
GGC03_RS15345	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GGC03_RS15350	COG0137	argininosuccinate synthase activity
GGC03_RS15360	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GGC03_RS15365	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GGC03_RS15460	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GGC03_RS15470	COG4206	TonB-dependent receptor
GGC03_RS15490	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GGC03_RS15495	COG0534	Mate efflux family protein
GGC03_RS15505	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GGC03_RS15510	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GGC03_RS15515	COG2937	Belongs to the GPAT DAPAT family
GGC03_RS15520	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
GGC03_RS15525	COG3161	chorismate lyase activity
GGC03_RS15530	COG1580	Controls the rotational direction of flagella during chemotaxis
GGC03_RS15540	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GGC03_RS15545	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GGC03_RS15550	COG2177	Part of the ABC transporter FtsEX involved in
GGC03_RS15555	COG2884	Cell division ATP-binding protein ftsE
GGC03_RS15560	COG0552	protein localization to endoplasmic reticulum
GGC03_RS15565	COG0742	ribosomal rna small subunit methyltransferase
GGC03_RS15575	COG2095	MarC family integral membrane protein
GGC03_RS15625	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GGC03_RS15630	COG0640	Transcriptional regulator
GGC03_RS15635	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
GGC03_RS15640	COG1280	lysine exporter protein (LysE YggA)
GGC03_RS15650	COG0561	phosphatase activity
GGC03_RS15665	COG3148	PFAM DTW domain containing protein
GGC03_RS15670	COG2199	diguanylate cyclase activity
GGC03_RS15670	COG2200	EAL domain
GGC03_RS15670	COG3287	FIST C domain
GGC03_RS15675	COG1011	Hydrolase
GGC03_RS15680	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
GGC03_RS15690	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GGC03_RS15695	COG0019	diaminopimelate decarboxylase activity
GGC03_RS15705	COG1965	Belongs to the frataxin family
GGC03_RS15710	COG3072	Adenylate cyclase
GGC03_RS15715	COG0181	hydroxymethylbilane synthase activity
GGC03_RS15720	COG1587	Uroporphyrinogen-III synthase
GGC03_RS15725	COG2959	enzyme of heme biosynthesis
GGC03_RS15730	COG3071	HemY protein
GGC03_RS15795	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GGC03_RS15810	COG3118	belongs to the thioredoxin family
GGC03_RS15820	COG0248	Ppx GppA phosphatase
GGC03_RS15825	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
GGC03_RS15835	COG0514	ATP-dependent DNA helicase (RecQ)
GGC03_RS15840	COG2962	Rard protein
GGC03_RS15850	COG1280	lysine exporter protein (LysE YggA)
GGC03_RS15855	COG0405	Gamma-glutamyltransferase
GGC03_RS15875	COG0210	DNA helicase
GGC03_RS15885	COG3220	belongs to the UPF0276 family
GGC03_RS15905	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
GGC03_RS15910	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GGC03_RS15925	COG1773	rubredoxin
GGC03_RS15940	COG0367	asparagine synthase
GGC03_RS15945	COG0477	Major facilitator Superfamily
GGC03_RS15965	COG0745	RESPONSE REGULATOR receiver
GGC03_RS15980	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GGC03_RS15985	COG0601	transmembrane transport
GGC03_RS15990	COG0747	negative chemotaxis
GGC03_RS16035	COG1309	transcriptional regulator
GGC03_RS16040	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GGC03_RS16045	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GGC03_RS16050	COG2960	long-chain fatty acid transporting porin activity
GGC03_RS16055	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GGC03_RS16060	COG0583	DNA-binding transcription factor activity
GGC03_RS16065	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GGC03_RS16095	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GGC03_RS16095	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GGC03_RS16115	COG0084	hydrolase, TatD family'
GGC03_RS16120	COG0805	protein transport
GGC03_RS16125	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GGC03_RS16130	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GGC03_RS16145	COG2226	methyltransferase
GGC03_RS16150	COG1322	Protein conserved in bacteria
GGC03_RS16160	COG1639	'signal transduction protein
GGC03_RS16190	COG2081	HI0933 family
GGC03_RS16200	COG1528	Iron-storage protein
GGC03_RS16205	COG0589	response to stress
GGC03_RS16220	COG0742	ribosomal rna small subunit methyltransferase
GGC03_RS16225	COG5001	Diguanylate cyclase
GGC03_RS16225	COG5002	protein histidine kinase activity
GGC03_RS16230	COG1522	sequence-specific DNA binding
GGC03_RS16255	COG0006	proline dipeptidase activity
GGC03_RS16255	COG0006	proline dipeptidase activity
GGC03_RS16265	COG2022	thiamine diphosphate biosynthetic process
GGC03_RS16275	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GGC03_RS16280	COG0352	thiamine-phosphate diphosphorylase activity
GGC03_RS16295	COG2132	Multicopper oxidase
GGC03_RS16355	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GGC03_RS16360	COG1739	Uncharacterized protein family UPF0029
GGC03_RS16370	COG0183	Belongs to the thiolase family
GGC03_RS16375	COG3706	GGDEF domain
GGC03_RS16380	COG0583	DNA-binding transcription factor activity
GGC03_RS16385	COG2814	Major facilitator Superfamily
GGC03_RS16395	COG0765	amino acid transport
GGC03_RS16405	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GGC03_RS16410	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GGC03_RS16415	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GGC03_RS16420	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GGC03_RS16425	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GGC03_RS16445	COG3312	ion transport
GGC03_RS16450	COG1475	DNA binding
GGC03_RS16455	COG1192	Involved in chromosome partitioning
GGC03_RS16460	COG0357	Ribosomal RNA small subunit methyltransferase G
GGC03_RS16465	COG0445	tRNA wobble uridine modification
GGC03_RS16470	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GGC03_RS16475	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GGC03_RS16480	COG0706	membrane insertase activity
GGC03_RS16495	COG0230	Belongs to the bacterial ribosomal protein bL34 family
GGC03_RS16500	COG1126	abc transporter atp-binding protein
GGC03_RS16520	COG0697	spore germination
GGC03_RS16550	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GGC03_RS16580	COG0840	transmembrane signaling receptor activity
GGC03_RS16610	COG0840	transmembrane signaling receptor activity
GGC03_RS16620	COG4580	involved in the transport of maltose and maltodextrins
GGC03_RS16635	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GGC03_RS16645	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GGC03_RS16650	COG0509	glycine decarboxylation via glycine cleavage system
GGC03_RS16670	COG0583	DNA-binding transcription factor activity
GGC03_RS16680	COG1132	(ABC) transporter
GGC03_RS16685	COG0589	response to stress
GGC03_RS16695	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GGC03_RS16695	COG2111	Na H antiporter
GGC03_RS16700	COG1006	Multisubunit Na H antiporter MnhC subunit
GGC03_RS16705	COG0651	ATP synthesis coupled electron transport
GGC03_RS16710	COG1863	multisubunit Na H antiporter MnhE subunit
GGC03_RS16715	COG2212	antiporter activity
GGC03_RS16720	COG1320	monovalent cation:proton antiporter activity
GGC03_RS16725	COG4191	Histidine kinase
GGC03_RS16725	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GGC03_RS16755	COG0488	(ABC) transporter
GGC03_RS16760	COG0673	inositol 2-dehydrogenase activity
GGC03_RS16770	COG5553	Cysteine dioxygenase type I
GGC03_RS16775	COG0300	oxidoreductase activity
GGC03_RS16800	COG3047	cAMP biosynthetic process
GGC03_RS16805	COG0739	heme binding
GGC03_RS16830	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GGC03_RS16835	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GGC03_RS16840	COG0446	pyridine nucleotide-disulphide oxidoreductase
GGC03_RS16845	COG3383	formate dehydrogenase (NAD+) activity
GGC03_RS16855	COG0004	ammonium transporteR
GGC03_RS16885	COG1234	tRNA 3'-trailer cleavage
GGC03_RS16890	COG0583	DNA-binding transcription factor activity
GGC03_RS16910	COG3304	Inner membrane component domain
GGC03_RS16915	COG2329	Antibiotic biosynthesis monooxygenase
GGC03_RS16925	COG3046	protein related to deoxyribodipyrimidine photolyase
GGC03_RS16930	COG0415	Belongs to the DNA photolyase family
GGC03_RS16960	COG3604	Transcriptional regulator
GGC03_RS16975	COG0583	DNA-binding transcription factor activity
GGC03_RS16985	COG1151	hydroxylamine reductase activity
GGC03_RS16990	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GGC03_RS16995	COG0583	DNA-binding transcription factor activity
GGC03_RS17005	COG3314	Sporulation integral membrane protein YlbJ
GGC03_RS17040	COG0745	RESPONSE REGULATOR receiver
GGC03_RS17055	COG1288	antiporter activity
GGC03_RS17060	COG3608	succinylglutamate desuccinylase aspartoacylase
GGC03_RS17090	COG1522	sequence-specific DNA binding
GGC03_RS17100	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
GGC03_RS17105	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
GGC03_RS17110	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GGC03_RS17140	COG0840	transmembrane signaling receptor activity
GGC03_RS17145	COG0454	-acetyltransferase
GGC03_RS17160	COG0363	glucosamine-6-phosphate deaminase activity
GGC03_RS17165	COG4720	Psort location CytoplasmicMembrane, score
GGC03_RS17170	COG1122	ATPase activity
GGC03_RS17190	COG1162	GTPase activity
GGC03_RS17195	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
GGC03_RS17210	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GGC03_RS17215	COG0581	inorganic phosphate transmembrane transporter activity
GGC03_RS17220	COG0573	inorganic phosphate transmembrane transporter activity
GGC03_RS17230	COG0840	transmembrane signaling receptor activity
GGC03_RS17235	COG4221	oxidoreductase activity
GGC03_RS17255	COG1477	protein flavinylation
GGC03_RS17310	COG2894	cell division
GGC03_RS17320	COG4964	Belongs to the GSP D family
GGC03_RS17355	COG2095	MarC family integral membrane protein
GGC03_RS17375	COG4176	ABC-type proline glycine betaine transport system permease component
GGC03_RS17380	COG4175	Glycine betaine
GGC03_RS17380	COG3448	diguanylate cyclase activity
GGC03_RS17390	COG0657	acetylesterase activity
GGC03_RS17440	COG0590	tRNA wobble adenosine to inosine editing
GGC03_RS17445	COG2076	Multidrug Resistance protein
GGC03_RS17450	COG2076	Multidrug Resistance protein
GGC03_RS17455	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
GGC03_RS17460	COG1960	acyl-CoA dehydrogenase activity
GGC03_RS17465	COG0662	Cupin 2, conserved barrel domain protein
GGC03_RS17475	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GGC03_RS17485	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GGC03_RS17510	COG4264	IucA IucC family
GGC03_RS17525	COG1120	ATPase activity
GGC03_RS17530	COG2814	Major facilitator Superfamily
GGC03_RS17540	COG4968	Prepilin-type N-terminal cleavage methylation domain
GGC03_RS17545	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GGC03_RS17545	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GGC03_RS17545	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GGC03_RS17555	COG0383	alpha-mannosidase activity
GGC03_RS17560	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GGC03_RS17560	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GGC03_RS17560	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
GGC03_RS17585	COG0583	DNA-binding transcription factor activity
GGC03_RS17595	COG1028	Short-chain dehydrogenase reductase Sdr
GGC03_RS17600	COG1414	Transcriptional regulator
GGC03_RS17625	COG0702	epimerase
GGC03_RS17670	COG1733	regulation of RNA biosynthetic process
GGC03_RS17690	COG1917	Cupin 2, conserved barrel domain protein
GGC03_RS17690	COG4977	sequence-specific DNA binding
GGC03_RS17695	COG4771	TonB-dependent receptor
GGC03_RS17700	COG2814	Major facilitator Superfamily
GGC03_RS17705	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GGC03_RS17705	COG2226	methyltransferase
GGC03_RS17705	COG3433	isochorismatase activity
GGC03_RS17725	COG1169	isochorismate synthase
GGC03_RS17730	COG1021	2,3-dihydroxybenzoate-AMP ligase
GGC03_RS17735	COG1132	(ABC) transporter
GGC03_RS17740	COG1132	(ABC) transporter
GGC03_RS17780	COG0561	phosphatase activity
GGC03_RS17830	COG0300	oxidoreductase activity
GGC03_RS17840	COG0583	DNA-binding transcription factor activity
GGC03_RS17850	COG2249	NAD(P)H dehydrogenase (quinone) activity
GGC03_RS17900	COG1619	proteins homologs of microcin C7 resistance protein MccF
GGC03_RS17915	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GGC03_RS17920	COG1640	4-alpha-glucanotransferase
GGC03_RS17925	COG0058	SHG alpha-glucan phosphorylase activity
GGC03_RS17930	COG2909	trisaccharide binding
GGC03_RS17940	COG0456	acetyltransferase
GGC03_RS17975	COG2207	Transcriptional regulator
GGC03_RS17980	COG1335	isochorismatase
GGC03_RS17985	COG1404	Belongs to the peptidase S8 family
GGC03_RS17990	COG0402	S-adenosylhomocysteine deaminase activity
GGC03_RS18020	COG3795	YCII-related domain
GGC03_RS18045	COG2186	Transcriptional regulator
GGC03_RS18055	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GGC03_RS18065	COG0402	S-adenosylhomocysteine deaminase activity
GGC03_RS18070	COG2226	methyltransferase
GGC03_RS18075	COG5002	protein histidine kinase activity
GGC03_RS18075	COG0784	Response regulator, receiver
GGC03_RS18075	COG2205	protein histidine kinase activity
GGC03_RS18085	COG1522	sequence-specific DNA binding
GGC03_RS18095	COG0840	transmembrane signaling receptor activity
GGC03_RS18110	COG4266	Belongs to the allantoicase family
GGC03_RS18130	COG2252	PERMEase
GGC03_RS18145	COG0596	Alpha beta hydrolase
GGC03_RS18150	COG3214	Protein conserved in bacteria
GGC03_RS18165	COG2205	protein histidine kinase activity
GGC03_RS18175	COG0583	DNA-binding transcription factor activity
GGC03_RS18205	COG3179	chitinase
GGC03_RS18220	COG0109	protoheme IX farnesyltransferase activity
GGC03_RS18225	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GGC03_RS18230	COG1845	cytochrome c oxidase, subunit III
GGC03_RS18235	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GGC03_RS18240	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GGC03_RS18250	COG2706	6-phosphogluconolactonase activity
GGC03_RS18260	COG0800	Aldolase
GGC03_RS18265	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GGC03_RS18270	COG4145	pantothenate transmembrane transporter activity
GGC03_RS18280	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
GGC03_RS18295	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GGC03_RS18300	COG0840	transmembrane signaling receptor activity
GGC03_RS18345	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
GGC03_RS18350	COG0804	urea catabolic process
GGC03_RS18355	COG0832	Belongs to the urease beta subunit family
GGC03_RS18360	COG0831	urea catabolic process
GGC03_RS18385	COG0559	Belongs to the binding-protein-dependent transport system permease family
GGC03_RS18400	COG2015	COG2015, Alkyl sulfatase and related hydrolases
GGC03_RS18415	COG2084	Dehydrogenase
GGC03_RS18420	COG3622	Belongs to the hyi family
GGC03_RS18425	COG3960	tartronate-semialdehyde synthase activity
GGC03_RS18430	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GGC03_RS18440	COG0583	DNA-binding transcription factor activity
GGC03_RS18445	COG1288	antiporter activity
GGC03_RS18475	COG1846	Transcriptional regulator
GGC03_RS18480	COG0697	spore germination
GGC03_RS18485	COG5001	Diguanylate cyclase
GGC03_RS18485	COG3300	MHYT domain
GGC03_RS18500	COG1051	belongs to the nudix hydrolase family
GGC03_RS18505	COG0583	DNA-binding transcription factor activity
GGC03_RS18525	COG1733	regulation of RNA biosynthetic process
GGC03_RS18530	COG1028	Short-chain dehydrogenase reductase Sdr
GGC03_RS18540	COG1028	Short-chain dehydrogenase reductase Sdr
GGC03_RS18575	COG0444	Belongs to the ABC transporter superfamily
GGC03_RS18580	COG4608	Belongs to the ABC transporter superfamily
GGC03_RS18610	COG1444	tRNA N-acetyltransferase activity
GGC03_RS18615	COG0840	transmembrane signaling receptor activity
GGC03_RS18640	COG0835	chemotaxis
GGC03_RS18645	COG0840	transmembrane signaling receptor activity
GGC03_RS18650	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GGC03_RS18695	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GGC03_RS18720	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GGC03_RS18755	COG0583	DNA-binding transcription factor activity
GGC03_RS18760	COG1175	transmembrane transport
GGC03_RS18780	COG0546	phosphoglycolate phosphatase activity
GGC03_RS18785	COG3842	ATPase activity
GGC03_RS18790	COG0589	response to stress
GGC03_RS18795	COG2723	6-phospho-beta-galactosidase activity
GGC03_RS18800	COG0768	penicillin binding
GGC03_RS18805	COG0840	transmembrane signaling receptor activity
GGC03_RS18830	COG0583	DNA-binding transcription factor activity
GGC03_RS18845	COG0604	alcohol dehydrogenase
GGC03_RS18845	COG1028	Short-chain dehydrogenase reductase Sdr
GGC03_RS18845	COG3321	synthase
GGC03_RS18850	COG0656	L-ascorbic acid biosynthetic process
GGC03_RS18855	COG0351	phosphomethylpyrimidine kinase
GGC03_RS18860	COG1116	anion transmembrane transporter activity
GGC03_RS18865	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GGC03_RS18870	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GGC03_RS18875	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GGC03_RS18895	COG2207	Transcriptional regulator
GGC03_RS18895	COG3708	Transcriptional regulator
GGC03_RS18905	COG0671	phosphoesterase, PA-phosphatase related
GGC03_RS18915	COG0438	transferase activity, transferring glycosyl groups
GGC03_RS18925	COG1940	carbohydrate kinase activity
GGC03_RS18940	COG1175	transmembrane transport
GGC03_RS18950	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GGC03_RS18970	COG0583	DNA-binding transcription factor activity
GGC03_RS18990	COG1063	alcohol dehydrogenase
GGC03_RS19000	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GGC03_RS19000	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GGC03_RS19010	COG0251	oxidation-reduction process
GGC03_RS19015	COG0697	spore germination
GGC03_RS19030	COG1595	DNA-templated transcription, initiation
GGC03_RS19040	COG3314	Sporulation integral membrane protein YlbJ
GGC03_RS19070	COG0471	metal ion transport
GGC03_RS19075	COG2205	protein histidine kinase activity
GGC03_RS19080	COG0745	RESPONSE REGULATOR receiver
GGC03_RS19105	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GGC03_RS19115	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GGC03_RS19120	COG0745	RESPONSE REGULATOR receiver
GGC03_RS19125	COG2205	protein histidine kinase activity
GGC03_RS19125	COG3850	Histidine kinase
GGC03_RS19125	COG3437	response regulator, receiver
GGC03_RS19125	COG4999	Histidine kinase
GGC03_RS19140	COG5002	protein histidine kinase activity
GGC03_RS19145	COG0745	RESPONSE REGULATOR receiver
GGC03_RS19155	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GGC03_RS19170	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GGC03_RS19175	COG3366	ferrous iron transmembrane transporter activity
GGC03_RS19180	COG0700	Nucleoside recognition
GGC03_RS19190	COG2207	Transcriptional regulator
GGC03_RS19210	COG1301	dicarboxylic acid transport
GGC03_RS19365	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
GGC03_RS19390	COG0346	lactoylglutathione lyase activity
GGC03_RS19400	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GGC03_RS19410	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GGC03_RS19445	COG2814	Major facilitator Superfamily
GGC03_RS19450	COG0583	DNA-binding transcription factor activity
GGC03_RS19455	COG0393	Putative heavy-metal-binding
GGC03_RS19460	COG1671	Belongs to the UPF0178 family
GGC03_RS19475	COG1999	signal sequence binding
GGC03_RS19485	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GGC03_RS19490	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GGC03_RS19495	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
GGC03_RS19500	COG3033	Beta-eliminating lyase
GGC03_RS19530	COG0259	pyridoxamine-phosphate oxidase activity
GGC03_RS19540	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GGC03_RS19585	COG1132	(ABC) transporter
GGC03_RS19595	COG0583	DNA-binding transcription factor activity
GGC03_RS19610	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GGC03_RS19620	COG0786	glutamate:sodium symporter activity
GGC03_RS19625	COG1566	PFAM secretion protein HlyD family protein
GGC03_RS19640	COG3706	GGDEF domain
GGC03_RS19655	COG0813	purine-nucleoside phosphorylase activity
GGC03_RS19660	COG3272	Protein of unknown function (DUF1722)
GGC03_RS19665	COG0789	Transcriptional regulator
GGC03_RS19670	COG0415	Belongs to the DNA photolyase family
GGC03_RS19675	COG1388	LysM domain
GGC03_RS19675	COG1376	ErfK ybiS ycfS ynhG family protein
GGC03_RS19685	COG0513	Belongs to the DEAD box helicase family
GGC03_RS19690	COG3291	Pkd domain containing protein
GGC03_RS19700	COG3568	Endonuclease Exonuclease Phosphatase
GGC03_RS19735	COG0006	proline dipeptidase activity
GGC03_RS19750	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GGC03_RS19755	COG0601	transmembrane transport
GGC03_RS19770	COG2186	Transcriptional regulator
GGC03_RS19780	COG3938	Belongs to the proline racemase family
GGC03_RS19800	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GGC03_RS19805	COG3842	ATPase activity
GGC03_RS19810	COG1176	ABC-type spermidine putrescine transport system, permease component I
GGC03_RS19815	COG1177	transmembrane transport
GGC03_RS19825	COG1280	lysine exporter protein (LysE YggA)
GGC03_RS19835	COG1846	Transcriptional regulator
GGC03_RS19880	COG2988	succinylglutamate desuccinylase activity
GGC03_RS19885	COG0523	cobalamin synthesis protein
GGC03_RS19890	COG4451	ribulose bisphosphate carboxylase, small
GGC03_RS19890	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GGC03_RS19895	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GGC03_RS19950	COG0583	DNA-binding transcription factor activity
GGC03_RS19955	COG1280	lysine exporter protein (LysE YggA)
GGC03_RS19995	COG1253	flavin adenine dinucleotide binding
GGC03_RS20030	COG0583	DNA-binding transcription factor activity
GGC03_RS20035	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GGC03_RS20040	COG1686	Belongs to the peptidase S11 family
GGC03_RS20045	COG2814	Major facilitator Superfamily
GGC03_RS20055	COG1741	Belongs to the pirin family
GGC03_RS20070	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GGC03_RS20095	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GGC03_RS20105	COG3314	Sporulation integral membrane protein YlbJ
GGC03_RS20115	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
GGC03_RS20135	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GGC03_RS20140	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GGC03_RS20145	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GGC03_RS20150	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
GGC03_RS20175	COG1612	heme a metabolic process
GGC03_RS20180	COG0109	protoheme IX farnesyltransferase activity
GGC03_RS20185	COG0765	amino acid transport
GGC03_RS20190	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GGC03_RS20195	COG0765	amino acid transport
GGC03_RS20200	COG1126	abc transporter atp-binding protein
GGC03_RS20205	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GGC03_RS20215	COG0366	Alpha amylase catalytic
GGC03_RS20225	COG4989	oxidoreductase activity
GGC03_RS20230	COG3706	GGDEF domain
GGC03_RS20230	COG4251	negative regulation of phosphorylation
GGC03_RS20230	COG5001	Diguanylate cyclase
GGC03_RS20230	COG2203	Gaf domain
GGC03_RS20240	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GGC03_RS20245	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GGC03_RS20250	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GGC03_RS20255	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
GGC03_RS20260	COG0438	transferase activity, transferring glycosyl groups
GGC03_RS20275	COG1045	serine acetyltransferase
GGC03_RS20285	COG0438	transferase activity, transferring glycosyl groups
GGC03_RS20285	COG0297	glycogen (starch) synthase activity
GGC03_RS20295	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
GGC03_RS20345	COG5001	Diguanylate cyclase
GGC03_RS20350	COG0583	DNA-binding transcription factor activity
GGC03_RS20355	COG2814	Major facilitator Superfamily
GGC03_RS20370	COG0697	spore germination
GGC03_RS20380	COG0534	Mate efflux family protein
GGC03_RS20390	COG2249	NAD(P)H dehydrogenase (quinone) activity
GGC03_RS20395	COG0546	phosphoglycolate phosphatase activity
GGC03_RS20405	COG3604	Transcriptional regulator
GGC03_RS20410	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GGC03_RS20410	COG1017	nitric oxide dioxygenase activity
GGC03_RS20425	COG1278	Cold shock
GGC03_RS20430	COG3036	rescue of stalled ribosome
GGC03_RS20445	COG1686	Belongs to the peptidase S11 family
GGC03_RS20460	COG3530	Putative quorum-sensing-regulated virulence factor
GGC03_RS20480	COG1012	belongs to the aldehyde dehydrogenase family
GGC03_RS20495	COG1136	(ABC) transporter
GGC03_RS20515	COG3275	phosphorelay sensor kinase activity
GGC03_RS20520	COG3279	Response regulator of the LytR AlgR family
GGC03_RS20550	COG0366	Alpha amylase catalytic
GGC03_RS20570	COG0747	negative chemotaxis
GGC03_RS20575	COG4608	Belongs to the ABC transporter superfamily
GGC03_RS20580	COG0444	Belongs to the ABC transporter superfamily
GGC03_RS20585	COG0534	Mate efflux family protein
GGC03_RS20615	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GGC03_RS20630	COG2130	NADP-dependent
GGC03_RS20650	COG0642	Histidine kinase
GGC03_RS20670	COG5001	Diguanylate cyclase
GGC03_RS20675	COG1396	sequence-specific DNA binding
GGC03_RS20680	COG4948	Mandelate Racemase Muconate Lactonizing
GGC03_RS20690	COG0583	DNA-binding transcription factor activity
GGC03_RS20695	COG0443	Heat shock 70 kDa protein
GGC03_RS20725	COG1280	lysine exporter protein (LysE YggA)
GGC03_RS20740	COG4232	protein-disulfide reductase activity
GGC03_RS20745	COG3118	belongs to the thioredoxin family
GGC03_RS20785	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GGC03_RS20805	COG0668	transmembrane transport
GGC03_RS20815	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
GGC03_RS20820	COG3123	guanosine phosphorylase activity
GGC03_RS20835	COG0583	DNA-binding transcription factor activity
GGC03_RS20860	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
GGC03_RS20870	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GGC03_RS20870	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
GGC03_RS20875	COG3265	gluconokinase activity
GGC03_RS20880	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GGC03_RS20885	COG1609	Transcriptional regulator
GGC03_RS20905	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GGC03_RS20910	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GGC03_RS20915	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
GGC03_RS20920	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
GGC03_RS20950	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
GGC03_RS20955	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GGC03_RS20975	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GGC03_RS21000	COG0004	ammonium transporteR
GGC03_RS21015	COG3469	chitinase activity
GGC03_RS21025	COG1869	D-ribose catabolic process
GGC03_RS21030	COG1129	ABC transporter
GGC03_RS21035	COG1172	Belongs to the binding-protein-dependent transport system permease family
GGC03_RS21040	COG1879	ABC-type sugar transport system periplasmic component
GGC03_RS21045	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GGC03_RS21050	COG1609	Transcriptional regulator
GGC03_RS21055	COG0784	Response regulator, receiver
GGC03_RS21055	COG3437	response regulator, receiver
GGC03_RS21060	COG4191	Histidine kinase
GGC03_RS21060	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GGC03_RS21070	COG0513	Belongs to the DEAD box helicase family
GGC03_RS21080	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
GGC03_RS21090	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GGC03_RS21105	COG0739	heme binding
GGC03_RS21115	COG2814	Major facilitator Superfamily
GGC03_RS21120	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
GGC03_RS21125	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GGC03_RS21135	COG0848	biopolymer transport protein
GGC03_RS21140	COG0811	peptide transport
GGC03_RS21145	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
GGC03_RS21155	COG3721	Heme iron utilization protein
GGC03_RS21160	COG0748	coenzyme F420 binding
GGC03_RS21165	COG2096	Adenosyltransferase
GGC03_RS21170	COG3842	ATPase activity
GGC03_RS21180	COG1175	transmembrane transport
GGC03_RS21185	COG3833	ABC-type maltose transport systems, permease component
GGC03_RS21200	COG4533	DNA binding
GGC03_RS21240	COG0784	Response regulator, receiver
GGC03_RS21240	COG5002	protein histidine kinase activity
GGC03_RS21240	COG2205	protein histidine kinase activity
GGC03_RS21250	COG0861	Integral membrane protein TerC family
GGC03_RS21255	COG0402	S-adenosylhomocysteine deaminase activity
GGC03_RS21260	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GGC03_RS21265	COG1566	PFAM secretion protein HlyD family protein
GGC03_RS21290	COG0745	RESPONSE REGULATOR receiver
GGC03_RS21315	COG0531	amino acid
GGC03_RS21335	COG0673	inositol 2-dehydrogenase activity
GGC03_RS21340	COG1765	OsmC-like protein
GGC03_RS21345	COG0110	maltose O-acetyltransferase activity
GGC03_RS21365	COG2304	oxidoreductase activity
GGC03_RS21370	COG2304	oxidoreductase activity
GGC03_RS21385	COG0714	Associated with various cellular activities
GGC03_RS21400	COG0583	DNA-binding transcription factor activity
GGC03_RS21405	COG0667	Aldo Keto reductase
GGC03_RS21420	COG2205	protein histidine kinase activity
GGC03_RS21425	COG0745	RESPONSE REGULATOR receiver
GGC03_RS21435	COG0745	RESPONSE REGULATOR receiver
GGC03_RS21440	COG2205	protein histidine kinase activity
GGC03_RS21445	COG4452	Inner membrane protein CreD
GGC03_RS21455	COG0346	lactoylglutathione lyase activity
GGC03_RS21475	COG2199	diguanylate cyclase activity
GGC03_RS21475	COG2200	EAL domain
GGC03_RS21475	COG2202	Pas domain
GGC03_RS21480	COG0156	8-amino-7-oxononanoate synthase activity
GGC03_RS21485	COG1063	alcohol dehydrogenase
GGC03_RS21515	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GGC03_RS21525	COG2195	Cleaves the N-terminal amino acid of tripeptides
GGC03_RS21545	COG0798	PFAM Bile acid sodium symporter
GGC03_RS21555	COG0612	Peptidase, M16
GGC03_RS21560	COG2205	protein histidine kinase activity
GGC03_RS21560	COG0784	Response regulator, receiver
GGC03_RS21565	COG2205	protein histidine kinase activity
GGC03_RS21565	COG0784	Response regulator, receiver
GGC03_RS21585	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GGC03_RS21590	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GGC03_RS21595	COG3186	Phenylalanine-4-hydroxylase
GGC03_RS21645	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GGC03_RS21650	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GGC03_RS21695	COG1454	alcohol dehydrogenase
GGC03_RS21700	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
GGC03_RS21710	COG1011	Hydrolase
GGC03_RS21720	COG2378	regulation of single-species biofilm formation
GGC03_RS21740	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GGC03_RS21745	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GGC03_RS21750	COG1840	ABC-type Fe3 transport system, periplasmic component
GGC03_RS21760	COG3842	ATPase activity
GGC03_RS21785	COG3104	oligopeptide transport
GGC03_RS21790	COG2866	Carboxypeptidase
GGC03_RS21795	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GGC03_RS21800	COG0583	DNA-binding transcription factor activity
GGC03_RS21805	COG1760	l-serine dehydratase
GGC03_RS21830	COG3706	GGDEF domain
GGC03_RS21835	COG0835	chemotaxis
GGC03_RS21835	COG0784	Response regulator, receiver
GGC03_RS21840	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GGC03_RS21855	COG1028	Short-chain dehydrogenase reductase Sdr
GGC03_RS21865	COG0494	nUDIX hydrolase
GGC03_RS21870	COG0714	Associated with various cellular activities
GGC03_RS21875	COG2425	protein containing a von Willebrand factor type A (vWA) domain
GGC03_RS21880	COG2814	Major facilitator Superfamily
GGC03_RS21905	COG3706	GGDEF domain
GGC03_RS21910	COG1846	Transcriptional regulator
GGC03_RS21915	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GGC03_RS21920	COG2176	DNA-directed DNA polymerase activity
GGC03_RS21930	COG0789	Transcriptional regulator
GGC03_RS21940	COG3300	MHYT domain
GGC03_RS21940	COG5001	Diguanylate cyclase
GGC03_RS21945	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GGC03_RS21950	COG0583	DNA-binding transcription factor activity
GGC03_RS21975	COG1858	cytochrome C peroxidase
GGC03_RS22000	COG1716	ATPase activity
GGC03_RS22000	COG5001	Diguanylate cyclase
GGC03_RS22020	COG2910	NAD(P)H-binding
GGC03_RS22025	COG0583	DNA-binding transcription factor activity
GGC03_RS22030	COG1115	amino acid carrier protein
GGC03_RS22045	COG1741	Belongs to the pirin family
GGC03_RS22050	COG2259	Doxx family
GGC03_RS22085	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GGC03_RS22090	COG1960	acyl-CoA dehydrogenase activity
GGC03_RS22100	COG0183	Belongs to the thiolase family
GGC03_RS22110	COG1960	acyl-CoA dehydrogenase activity
GGC03_RS22115	COG1024	Enoyl-CoA hydratase
GGC03_RS22120	COG1024	Enoyl-CoA hydratase
GGC03_RS22130	COG1028	Short-chain dehydrogenase reductase Sdr
GGC03_RS22135	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
GGC03_RS22155	COG3706	GGDEF domain
GGC03_RS22180	COG2199	diguanylate cyclase activity
GGC03_RS22180	COG2203	Gaf domain
GGC03_RS22190	COG2315	Protein conserved in bacteria
GGC03_RS22235	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GGC03_RS22235	COG1648	precorrin-2 dehydrogenase activity
GGC03_RS22240	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GGC03_RS22250	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GGC03_RS22250	COG1116	anion transmembrane transporter activity
GGC03_RS22255	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GGC03_RS22260	COG1116	anion transmembrane transporter activity
GGC03_RS22265	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GGC03_RS22265	COG2146	nitrite reductase [NAD(P)H] activity
GGC03_RS22270	COG2146	nitrite reductase [NAD(P)H] activity
GGC03_RS22295	COG3118	belongs to the thioredoxin family
GGC03_RS22300	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GGC03_RS22310	COG0419	ATPase involved in DNA repair
GGC03_RS22315	COG2205	protein histidine kinase activity
GGC03_RS22315	COG0784	Response regulator, receiver
GGC03_RS22320	COG0156	8-amino-7-oxononanoate synthase activity
GGC03_RS22330	COG0038	chloride channel
GGC03_RS22335	COG0523	cobalamin synthesis protein
GGC03_RS22340	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GGC03_RS22350	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GGC03_RS22385	COG1522	sequence-specific DNA binding
GGC03_RS22395	COG1473	amidohydrolase
GGC03_RS22400	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GGC03_RS22405	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
GGC03_RS22410	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GGC03_RS22415	COG0006	proline dipeptidase activity
GGC03_RS22425	COG1522	sequence-specific DNA binding
GGC03_RS22430	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GGC03_RS22435	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GGC03_RS22460	COG2897	thiosulfate sulfurtransferase activity
GGC03_RS22470	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GGC03_RS22485	COG0513	Belongs to the DEAD box helicase family
GGC03_RS22495	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GGC03_RS22495	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GGC03_RS22500	COG0814	amino acid
GGC03_RS22510	COG0513	Belongs to the DEAD box helicase family
GGC03_RS22540	COG1214	PFAM Peptidase M22, glycoprotease
GGC03_RS22540	COG0456	acetyltransferase
GGC03_RS22555	COG0346	lactoylglutathione lyase activity
GGC03_RS22565	COG3048	D-serine ammonia-lyase activity
GGC03_RS22570	COG0583	DNA-binding transcription factor activity
GGC03_RS22580	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GGC03_RS22585	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GGC03_RS22600	COG0546	phosphoglycolate phosphatase activity
GGC03_RS22610	COG0800	Aldolase
GGC03_RS22615	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GGC03_RS22620	COG1263	PTS System
GGC03_RS22620	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GGC03_RS22630	COG2188	Transcriptional regulator
GGC03_RS22635	COG1803	Methylglyoxal synthase
GGC03_RS22640	COG1879	ABC-type sugar transport system periplasmic component
GGC03_RS22645	COG2205	protein histidine kinase activity
GGC03_RS22645	COG2198	Histidine kinase
GGC03_RS22645	COG0784	Response regulator, receiver
GGC03_RS22660	COG1979	alcohol dehydrogenase
GGC03_RS22665	COG2207	Transcriptional regulator
GGC03_RS22670	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GGC03_RS22675	COG3706	GGDEF domain
GGC03_RS22680	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GGC03_RS22680	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GGC03_RS22680	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
GGC03_RS22685	COG1105	Belongs to the carbohydrate kinase PfkB family
GGC03_RS22690	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GGC03_RS22690	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GGC03_RS22695	COG1609	Transcriptional regulator
GGC03_RS22715	COG0725	ABC transporter, periplasmic molybdate-binding protein
GGC03_RS22720	COG4149	molybdate abc transporter
GGC03_RS22725	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
GGC03_RS22735	COG4251	negative regulation of phosphorylation
GGC03_RS22735	COG3706	GGDEF domain
GGC03_RS22735	COG5001	Diguanylate cyclase
GGC03_RS22735	COG2203	Gaf domain
GGC03_RS22740	COG3706	GGDEF domain
GGC03_RS22755	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
GGC03_RS22760	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
GGC03_RS22770	COG0745	RESPONSE REGULATOR receiver
GGC03_RS22785	COG3140	Belongs to the UPF0181 family
GGC03_RS22800	COG0023	Translation Initiation Factor
GGC03_RS22815	COG1181	Belongs to the D-alanine--D-alanine ligase family
GGC03_RS22820	COG3266	domain, Protein
GGC03_RS22825	COG0045	succinate-CoA ligase (ADP-forming) activity
GGC03_RS22825	COG1042	CoA-binding domain protein
GGC03_RS22825	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GGC03_RS22830	COG0583	DNA-binding transcription factor activity
GGC03_RS22835	COG1629	transport
GGC03_RS22835	COG4771	TonB-dependent receptor
GGC03_RS22855	COG2050	protein possibly involved in aromatic compounds catabolism
GGC03_RS22875	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GGC03_RS22880	COG3070	regulator of competence-specific genes
GGC03_RS22885	COG0840	transmembrane signaling receptor activity
GGC03_RS22890	COG2205	protein histidine kinase activity
GGC03_RS22890	COG0784	Response regulator, receiver
GGC03_RS22895	COG0745	RESPONSE REGULATOR receiver
GGC03_RS22910	COG1605	Chorismate mutase
GGC03_RS22940	COG0737	Belongs to the 5'-nucleotidase family
GGC03_RS22945	COG3593	DNA synthesis involved in DNA repair
GGC03_RS22955	COG0583	DNA-binding transcription factor activity
GGC03_RS22960	COG2116	formate transmembrane transporter activity
GGC03_RS22965	COG2353	YceI-like domain
GGC03_RS22970	COG3038	cytochrome b561
GGC03_RS22990	COG3069	C4-dicarboxylate transmembrane transporter activity
GGC03_RS22995	COG2197	response regulator
GGC03_RS23000	COG3850	Histidine kinase
GGC03_RS23005	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GGC03_RS23015	COG0243	molybdopterin cofactor binding
GGC03_RS23035	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GGC03_RS23040	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
GGC03_RS23050	COG1984	allophanate hydrolase subunit 2
GGC03_RS23055	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
GGC03_RS23060	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
GGC03_RS23065	COG4181	ATPase activity
GGC03_RS23075	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GGC03_RS23080	COG3300	MHYT domain
GGC03_RS23080	COG5001	Diguanylate cyclase
GGC03_RS23090	COG0484	heat shock protein binding
GGC03_RS23110	COG0210	DNA helicase
GGC03_RS23115	COG1289	transmembrane transporter activity
GGC03_RS23140	COG5002	protein histidine kinase activity
GGC03_RS23140	COG0784	Response regulator, receiver
GGC03_RS23155	COG2827	Endonuclease containing a URI domain
GGC03_RS23160	COG3132	Protein of unknown function, DUF480
GGC03_RS23170	COG2926	Belongs to the UPF0265 family
GGC03_RS23180	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GGC03_RS23185	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GGC03_RS23190	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GGC03_RS23195	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
GGC03_RS23200	COG0247	lactate metabolic process
GGC03_RS23220	COG0545	Peptidyl-prolyl cis-trans isomerase
GGC03_RS23230	COG4067	protein conserved in archaea
GGC03_RS23230	COG0189	ligase activity
GGC03_RS23240	COG0602	queuosine metabolic process
GGC03_RS23245	COG1328	CTP reductase activity
GGC03_RS23295	COG3240	lipase activity
GGC03_RS23300	COG2814	Major facilitator Superfamily
GGC03_RS23305	COG1794	racemase activity, acting on amino acids and derivatives
GGC03_RS23320	COG0183	Belongs to the thiolase family
GGC03_RS23335	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GGC03_RS23340	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GGC03_RS23345	COG1309	transcriptional regulator
GGC03_RS23350	COG1609	Transcriptional regulator
GGC03_RS23365	COG2211	Major facilitator Superfamily
GGC03_RS23370	COG3250	beta-galactosidase activity
GGC03_RS23410	COG1522	sequence-specific DNA binding
GGC03_RS23445	COG0515	serine threonine protein kinase
GGC03_RS23445	COG2815	serine threonine protein kinase
GGC03_RS23470	COG3501	Rhs element vgr protein
GGC03_RS23510	COG0739	heme binding
GGC03_RS23520	COG2203	Gaf domain
GGC03_RS23520	COG2199	diguanylate cyclase activity
GGC03_RS23525	COG0840	transmembrane signaling receptor activity
GGC03_RS23535	COG2271	Major facilitator Superfamily
GGC03_RS23555	COG4206	TonB-dependent receptor
GGC03_RS23565	COG0004	ammonium transporteR
GGC03_RS23580	COG2759	Belongs to the formate--tetrahydrofolate ligase family
GGC03_RS23585	COG4604	ABC transporter, ATP-binding protein
GGC03_RS23590	COG4605	iron ion homeostasis
GGC03_RS23595	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GGC03_RS23645	COG4172	Belongs to the ABC transporter superfamily
GGC03_RS23650	COG4239	(ABC) transporter, permease
GGC03_RS23655	COG4174	ABC transporter (Permease)
GGC03_RS23660	COG4166	transmembrane transport
GGC03_RS23675	COG0840	transmembrane signaling receptor activity
GGC03_RS23680	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GGC03_RS23685	COG1067	ATP-dependent peptidase activity
GGC03_RS23695	COG4172	Belongs to the ABC transporter superfamily
GGC03_RS23700	COG0583	DNA-binding transcription factor activity
GGC03_RS23705	COG1620	l-lactate permease
GGC03_RS23710	COG1304	FMN binding
GGC03_RS23730	COG4175	Glycine betaine
GGC03_RS23730	COG3448	diguanylate cyclase activity
GGC03_RS23750	COG1012	belongs to the aldehyde dehydrogenase family
GGC03_RS23755	COG1309	transcriptional regulator
GGC03_RS23770	COG1404	Belongs to the peptidase S8 family
GGC03_RS23775	COG1346	cytolysis
GGC03_RS23785	COG0516	GMP reductase activity
GGC03_RS23790	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GGC03_RS23790	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GGC03_RS23805	COG3437	response regulator, receiver
GGC03_RS23810	COG2205	protein histidine kinase activity
GGC03_RS23810	COG3437	response regulator, receiver
GGC03_RS23810	COG3850	Histidine kinase
GGC03_RS23810	COG4999	Histidine kinase
GGC03_RS23820	COG2172	sigma factor antagonist activity
GGC03_RS23830	COG1366	Belongs to the anti-sigma-factor antagonist family
GGC03_RS23835	COG0840	transmembrane signaling receptor activity
GGC03_RS23875	COG0366	Alpha amylase catalytic
GGC03_RS23885	COG2354	Protein conserved in bacteria
GGC03_RS23905	COG2199	diguanylate cyclase activity
GGC03_RS23910	COG1349	DNA-binding transcription factor activity
GGC03_RS23920	COG3217	Mosc domain protein beta barrel domain protein
GGC03_RS23920	COG3217	Mosc domain protein beta barrel domain protein
GGC03_RS23920	COG0633	Ferredoxin
GGC03_RS23920	COG0633	Ferredoxin
GGC03_RS23925	COG0418	dihydroorotase activity
GGC03_RS23945	COG2197	response regulator
GGC03_RS23950	COG3851	Histidine kinase
GGC03_RS23955	COG2271	Major facilitator Superfamily
GGC03_RS23965	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GGC03_RS23975	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GGC03_RS23980	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GGC03_RS23985	COG0363	glucosamine-6-phosphate deaminase activity
GGC03_RS23990	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GGC03_RS24010	COG3284	Transcriptional regulator
GGC03_RS24015	COG1012	belongs to the aldehyde dehydrogenase family
GGC03_RS24045	COG0579	oxidoreductase
GGC03_RS24050	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GGC03_RS24055	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GGC03_RS24065	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GGC03_RS24070	COG0840	transmembrane signaling receptor activity
GGC03_RS24095	COG2814	Major facilitator Superfamily
GGC03_RS24100	COG0583	DNA-binding transcription factor activity
GGC03_RS24125	COG0564	pseudouridine synthase activity
GGC03_RS24155	COG0251	oxidation-reduction process
GGC03_RS24195	COG0110	maltose O-acetyltransferase activity
GGC03_RS24205	COG1621	beta-fructofuranosidase activity
GGC03_RS24215	COG3842	ATPase activity
GGC03_RS24220	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GGC03_RS24225	COG1554	hydrolase, family 65, central catalytic
GGC03_RS24230	COG0395	ABC-type sugar transport system, permease component
GGC03_RS24235	COG1175	transmembrane transport
GGC03_RS24250	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GGC03_RS24260	COG0573	inorganic phosphate transmembrane transporter activity
GGC03_RS24300	COG1574	metal-dependent hydrolase with the TIM-barrel fold
GGC03_RS24310	COG0513	Belongs to the DEAD box helicase family
GGC03_RS24315	COG3097	Belongs to the UPF0267 family
GGC03_RS24330	COG3706	GGDEF domain
GGC03_RS24335	COG1309	transcriptional regulator
GGC03_RS24340	COG2130	NADP-dependent
GGC03_RS24355	COG2084	Dehydrogenase
GGC03_RS24375	COG0366	Alpha amylase catalytic
GGC03_RS24385	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GGC03_RS24390	COG0625	glutathione transferase activity
GGC03_RS24395	COG0346	lactoylglutathione lyase activity
GGC03_RS24400	COG1054	Belongs to the UPF0176 family
GGC03_RS24430	COG1131	(ABC) transporter
GGC03_RS24435	COG0842	Transport permease protein
GGC03_RS24470	COG5002	protein histidine kinase activity
GGC03_RS24475	COG0745	RESPONSE REGULATOR receiver
GGC03_RS24495	COG1309	transcriptional regulator
GGC03_RS24505	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GGC03_RS24530	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GGC03_RS24555	COG1805	sodium ion transport
GGC03_RS24560	COG1271	oxidase subunit
GGC03_RS24565	COG1294	oxidase, subunit
GGC03_RS24575	COG1357	PFAM Pentapeptide repeats (8 copies)
GGC03_RS24600	COG1522	sequence-specific DNA binding
GGC03_RS24610	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GGC03_RS24630	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GGC03_RS24635	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GGC03_RS24635	COG2207	Transcriptional regulator
GGC03_RS24675	COG1028	Short-chain dehydrogenase reductase Sdr
GGC03_RS24685	COG2274	protein secretion by the type I secretion system
GGC03_RS24695	COG2274	protein secretion by the type I secretion system
GGC03_RS24705	COG0583	DNA-binding transcription factor activity
GGC03_RS24735	COG1280	lysine exporter protein (LysE YggA)
GGC03_RS24740	COG2207	Transcriptional regulator
GGC03_RS24740	COG1917	Cupin 2, conserved barrel domain protein
GGC03_RS24760	COG0625	glutathione transferase activity
GGC03_RS24765	COG0583	DNA-binding transcription factor activity
GGC03_RS24790	COG2207	Transcriptional regulator
GGC03_RS24790	COG1917	Cupin 2, conserved barrel domain protein
GGC03_RS24800	COG4608	Belongs to the ABC transporter superfamily
GGC03_RS24805	COG0444	Belongs to the ABC transporter superfamily
GGC03_RS24810	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GGC03_RS24830	COG1609	Transcriptional regulator
GGC03_RS24840	COG4580	involved in the transport of maltose and maltodextrins
GGC03_RS24850	COG1472	Belongs to the glycosyl hydrolase 3 family
GGC03_RS24870	COG0071	Belongs to the small heat shock protein (HSP20) family
GGC03_RS24875	COG0459	protein refolding
GGC03_RS24880	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GGC03_RS24900	COG1917	Cupin 2, conserved barrel domain protein
GGC03_RS24900	COG2169	Transcriptional regulator
GGC03_RS24955	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
GGC03_RS24965	COG1335	isochorismatase
GGC03_RS24970	COG2169	Transcriptional regulator
GGC03_RS24995	COG2267	carboxylic ester hydrolase activity
GGC03_RS25030	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GGC03_RS25040	COG4251	negative regulation of phosphorylation
GGC03_RS25040	COG3706	GGDEF domain
GGC03_RS25040	COG2203	Gaf domain
GGC03_RS25040	COG5001	Diguanylate cyclase
GGC03_RS25080	COG2003	Belongs to the UPF0758 family
GGC03_RS25190	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GGC03_RS25320	COG4771	TonB-dependent receptor
GGC03_RS25330	COG4974	Belongs to the 'phage' integrase family
GGC03_RS25340	COG1028	Short-chain dehydrogenase reductase Sdr
GGC03_RS25345	COG0583	DNA-binding transcription factor activity
GGC03_RS25385	COG2026	Addiction module toxin, RelE StbE family
GGC03_RS25435	COG1609	Transcriptional regulator
GGC03_RS25445	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GGC03_RS25455	COG1280	lysine exporter protein (LysE YggA)
GGC03_RS25460	COG0735	belongs to the Fur family
GGC03_RS25575	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GGC03_RS25575	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GGC03_RS25585	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
GGC03_RS25605	COG1181	Belongs to the D-alanine--D-alanine ligase family
GGC03_RS25610	COG4191	Histidine kinase
GGC03_RS25675	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GGC03_RS25690	COG1192	Involved in chromosome partitioning
GGC03_RS25700	COG2814	Major facilitator Superfamily
GGC03_RS25755	COG4191	Histidine kinase
GGC03_RS25760	COG3300	MHYT domain
GGC03_RS25760	COG5001	Diguanylate cyclase
GGC03_RS25775	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GGC03_RS25775	COG4191	Histidine kinase
GGC03_RS25835	COG1309	transcriptional regulator
GGC03_RS25840	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GGC03_RS25850	COG1360	Flagellar Motor Protein
GGC03_RS25870	COG0702	epimerase
GGC03_RS25895	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
GGC03_RS25905	COG1879	ABC-type sugar transport system periplasmic component
GGC03_RS25920	COG3706	GGDEF domain
GGC03_RS25920	COG2203	Gaf domain
GGC03_RS25920	COG4251	negative regulation of phosphorylation
GGC03_RS25920	COG5001	Diguanylate cyclase
GGC03_RS25935	COG0431	NADPH-dependent FMN reductase
GGC03_RS25940	COG0583	DNA-binding transcription factor activity
GGC03_RS25945	COG0583	DNA-binding transcription factor activity
GGC03_RS25965	COG0840	transmembrane signaling receptor activity
GGC03_RS25980	COG2203	Gaf domain
GGC03_RS25980	COG4251	negative regulation of phosphorylation
GGC03_RS25980	COG3706	GGDEF domain
GGC03_RS25980	COG5001	Diguanylate cyclase
GGC03_RS25990	COG0745	RESPONSE REGULATOR receiver
GGC03_RS26000	COG1028	Short-chain dehydrogenase reductase Sdr
GGC03_RS26005	COG0583	DNA-binding transcription factor activity
GGC03_RS26015	COG3527	Alpha-acetolactate decarboxylase
GGC03_RS26025	COG0745	RESPONSE REGULATOR receiver
GGC03_RS26030	COG2205	protein histidine kinase activity
GGC03_RS26060	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
GGC03_RS26130	COG0671	phosphoesterase, PA-phosphatase related
GGC03_RS26145	COG0113	porphobilinogen synthase activity
GGC03_RS26150	COG0183	Belongs to the thiolase family
GGC03_RS26160	COG3246	L-lysine catabolic process to acetate
GGC03_RS26175	COG0604	alcohol dehydrogenase
GGC03_RS26190	COG0702	epimerase
GGC03_RS26210	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
GGC03_RS26220	COG0583	DNA-binding transcription factor activity
GGC03_RS26225	COG1028	Short-chain dehydrogenase reductase Sdr
GGC03_RS26325	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GGC03_RS26335	COG2084	Dehydrogenase
GGC03_RS26410	COG4774	siderophore transport
GGC03_RS26430	COG0494	nUDIX hydrolase
GGC03_RS26460	COG1742	UPF0060 membrane protein
GGC03_RS26465	COG0251	oxidation-reduction process
GGC03_RS26475	COG0583	DNA-binding transcription factor activity
GGC03_RS26505	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GGC03_RS26510	COG1051	belongs to the nudix hydrolase family
GGC03_RS26545	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GGC03_RS26545	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
GGC03_RS26630	COG0776	regulation of translation
GGC03_RS26665	COG0629	single-stranded DNA binding
GGC03_RS26850	COG5301	cellulose 1,4-beta-cellobiosidase activity
GGC03_RS26885	COG3549	Plasmid maintenance system killer
GGC03_RS26890	COG3093	addiction module antidote protein HigA
GGC03_RS26930	COG2247	cell wall binding repeat
GGC03_RS26930	COG0860	N-Acetylmuramoyl-L-alanine amidase
GGC03_RS27105	COG1959	2 iron, 2 sulfur cluster binding