locus-tag	class	description
GGC04_RS00010	COG0592	DNA-directed DNA polymerase activity
GGC04_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GGC04_RS00020	COG0187	DNA topoisomerase II activity
GGC04_RS00025	COG0071	Belongs to the small heat shock protein (HSP20) family
GGC04_RS00030	COG3977	Valine--pyruvate aminotransferase
GGC04_RS00035	COG0751	glycine-tRNA ligase activity
GGC04_RS00040	COG0752	glycyl-tRNA synthetase alpha subunit
GGC04_RS00045	COG2119	membrane
GGC04_RS00055	COG0425	Belongs to the sulfur carrier protein TusA family
GGC04_RS00070	COG0604	alcohol dehydrogenase
GGC04_RS00080	COG0129	dihydroxy-acid dehydratase activity
GGC04_RS00085	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GGC04_RS00090	COG3978	acetolactate synthase activity
GGC04_RS00100	COG0606	chelatase, subunit chli
GGC04_RS00195	COG0204	Acyl-transferase
GGC04_RS00200	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GGC04_RS00205	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GGC04_RS00215	COG3084	Protein conserved in bacteria
GGC04_RS00220	COG4326	sporulation control protein
GGC04_RS00225	COG1272	protein, Hemolysin III
GGC04_RS00235	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GGC04_RS00240	COG0569	domain protein
GGC04_RS00245	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GGC04_RS00245	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GGC04_RS00255	COG0242	peptide deformylase activity
GGC04_RS00260	COG0758	DNA mediated transformation
GGC04_RS00265	COG2922	Belongs to the Smg family
GGC04_RS00270	COG0551	DNA topoisomerase type I activity
GGC04_RS00275	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GGC04_RS00280	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GGC04_RS00290	COG0408	coproporphyrinogen oxidase activity
GGC04_RS00305	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GGC04_RS00345	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GGC04_RS00355	COG2204	response regulator
GGC04_RS00360	COG3852	Histidine kinase
GGC04_RS00365	COG0174	glutamine synthetase
GGC04_RS00370	COG1217	gtp-binding protein TYPA
GGC04_RS00380	COG1295	ribonuclease BN
GGC04_RS00385	COG1490	D-aminoacyl-tRNA deacylase activity
GGC04_RS00390	COG0456	acetyltransferase
GGC04_RS00400	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
GGC04_RS00410	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GGC04_RS00415	COG3031	protein transport across the cell outer membrane
GGC04_RS00425	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GGC04_RS00430	COG1459	type II secretion system
GGC04_RS00435	COG2165	general secretion pathway protein
GGC04_RS00440	COG2165	general secretion pathway protein
GGC04_RS00445	COG2165	general secretion pathway protein
GGC04_RS00450	COG4795	General secretion pathway protein
GGC04_RS00455	COG3156	type II secretion system protein K
GGC04_RS00460	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
GGC04_RS00465	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
GGC04_RS00485	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GGC04_RS00495	COG2183	response to ionizing radiation
GGC04_RS00505	COG0596	Alpha beta hydrolase
GGC04_RS00515	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
GGC04_RS00515	COG0316	Belongs to the HesB IscA family
GGC04_RS00520	COG0494	nUDIX hydrolase
GGC04_RS00525	COG1218	3'(2'),5'-bisphosphate nucleotidase
GGC04_RS00530	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GGC04_RS00535	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GGC04_RS00540	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GGC04_RS00545	COG1758	RNA polymerase activity
GGC04_RS00550	COG0194	GDP metabolic process
GGC04_RS00555	COG1595	DNA-templated transcription, initiation
GGC04_RS00585	COG0848	biopolymer transport protein
GGC04_RS00595	COG2252	PERMEase
GGC04_RS00600	COG2831	hemolysin activation secretion protein
GGC04_RS00605	COG3210	domain, Protein
GGC04_RS00620	COG1561	YicC-like family, N-terminal region
GGC04_RS00625	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
GGC04_RS00630	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GGC04_RS00635	COG1560	Kdo2-lipid A biosynthetic process
GGC04_RS00640	COG1560	Kdo2-lipid A biosynthetic process
GGC04_RS00645	COG1309	transcriptional regulator
GGC04_RS00650	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GGC04_RS00655	COG2003	Belongs to the UPF0758 family
GGC04_RS00660	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GGC04_RS00680	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GGC04_RS00685	COG0859	PFAM glycosyl transferase family 9
GGC04_RS00690	COG0463	Glycosyl transferase, family 2
GGC04_RS00695	COG0859	PFAM glycosyl transferase family 9
GGC04_RS00700	COG3642	lipopolysaccharide core region biosynthetic process
GGC04_RS00715	COG1519	Transferase
GGC04_RS00730	COG0859	PFAM glycosyl transferase family 9
GGC04_RS00760	COG1086	Polysaccharide biosynthesis protein
GGC04_RS00765	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GGC04_RS00775	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
GGC04_RS00780	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GGC04_RS00790	COG2089	acid synthase
GGC04_RS00800	COG0318	PFAM AMP-dependent synthetase and ligase
GGC04_RS00810	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
GGC04_RS00825	COG4310	Domain of unknown function (DUF2172)
GGC04_RS00835	COG2226	methyltransferase
GGC04_RS00875	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GGC04_RS00880	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GGC04_RS00885	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
GGC04_RS00885	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
GGC04_RS00890	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GGC04_RS00930	COG1494	fructose-1,6-bisphosphatase
GGC04_RS00935	COG3074	FtsZ-dependent cytokinesis
GGC04_RS00940	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GGC04_RS00945	COG0527	aspartate kinase activity
GGC04_RS00945	COG0460	homoserine dehydrogenase
GGC04_RS00950	COG0626	cystathionine gamma-synthase activity
GGC04_RS00955	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
GGC04_RS00960	COG0281	malic enzyme
GGC04_RS00970	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GGC04_RS00975	COG1609	Transcriptional regulator
GGC04_RS00980	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GGC04_RS00985	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GGC04_RS01010	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GGC04_RS01015	COG1053	succinate dehydrogenase
GGC04_RS01020	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
GGC04_RS01025	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GGC04_RS01060	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GGC04_RS01075	COG1045	serine acetyltransferase
GGC04_RS01080	COG1695	Transcriptional regulator
GGC04_RS01085	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
GGC04_RS01090	COG1573	uracil-dna glycosylase
GGC04_RS01095	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GGC04_RS01105	COG1253	flavin adenine dinucleotide binding
GGC04_RS01120	COG0151	Belongs to the GarS family
GGC04_RS01130	COG0789	Transcriptional regulator
GGC04_RS01135	COG2199	diguanylate cyclase activity
GGC04_RS01140	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
GGC04_RS01145	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GGC04_RS01150	COG2264	protein methyltransferase activity
GGC04_RS01155	COG0439	Biotin carboxylase
GGC04_RS01160	COG0511	ligase activity, forming carbon-carbon bonds
GGC04_RS01165	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GGC04_RS01170	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GGC04_RS01185	COG2814	Major facilitator Superfamily
GGC04_RS01190	COG0784	Response regulator, receiver
GGC04_RS01190	COG2205	protein histidine kinase activity
GGC04_RS01200	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GGC04_RS01210	COG2095	MarC family integral membrane protein
GGC04_RS01220	COG4232	protein-disulfide reductase activity
GGC04_RS01225	COG1438	arginine binding
GGC04_RS01230	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
GGC04_RS01235	COG0540	Belongs to the ATCase OTCase family
GGC04_RS01240	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GGC04_RS01255	COG1288	antiporter activity
GGC04_RS01260	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GGC04_RS01265	COG1027	Aspartate ammonia-lyase
GGC04_RS01345	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GGC04_RS01355	COG1012	belongs to the aldehyde dehydrogenase family
GGC04_RS01365	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GGC04_RS01370	COG3954	Phosphoribulokinase
GGC04_RS01380	COG0429	hydrolase of the alpha beta-hydrolase fold
GGC04_RS01390	COG0488	(ABC) transporter
GGC04_RS01410	COG1047	Peptidyl-prolyl cis-trans
GGC04_RS01420	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GGC04_RS01430	COG0402	S-adenosylhomocysteine deaminase activity
GGC04_RS01435	COG0557	exoribonuclease II activity
GGC04_RS01440	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GGC04_RS01445	COG0051	transcription antitermination factor activity, RNA binding
GGC04_RS01450	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GGC04_RS01455	COG0088	Forms part of the polypeptide exit tunnel
GGC04_RS01470	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GGC04_RS01475	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GGC04_RS01480	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GGC04_RS01495	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GGC04_RS01510	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GGC04_RS01525	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GGC04_RS01540	COG1841	ribosomal large subunit assembly
GGC04_RS01545	COG0200	Binds to the 23S rRNA
GGC04_RS01550	COG0201	protein transport
GGC04_RS01555	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GGC04_RS01560	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GGC04_RS01565	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GGC04_RS01575	COG0202	RNA polymerase activity
GGC04_RS01580	COG0203	ribosomal protein L17
GGC04_RS01590	COG0545	Peptidyl-prolyl cis-trans isomerase
GGC04_RS01605	COG2153	protein acetylation
GGC04_RS01615	COG0737	Belongs to the 5'-nucleotidase family
GGC04_RS01620	COG1648	precorrin-2 dehydrogenase activity
GGC04_RS01620	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GGC04_RS01635	COG0471	metal ion transport
GGC04_RS01635	COG3273	potassium ion transport
GGC04_RS01640	COG0529	Catalyzes the synthesis of activated sulfate
GGC04_RS01650	COG0735	belongs to the Fur family
GGC04_RS01660	COG3437	response regulator, receiver
GGC04_RS01690	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GGC04_RS01695	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GGC04_RS01700	COG0175	sulfate reduction
GGC04_RS01755	COG0646	methionine synthase
GGC04_RS01755	COG1410	methionine synthase
GGC04_RS01760	COG2239	Acts as a magnesium transporter
GGC04_RS01765	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GGC04_RS01770	COG1660	Displays ATPase and GTPase activities
GGC04_RS01775	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GGC04_RS01780	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GGC04_RS01790	COG1137	ATPase activity
GGC04_RS01795	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
GGC04_RS01805	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
GGC04_RS01810	COG0517	IMP dehydrogenase activity
GGC04_RS01810	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GGC04_RS01820	COG1127	ABC transporter
GGC04_RS01825	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GGC04_RS01830	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GGC04_RS01835	COG2854	intermembrane phospholipid transfer
GGC04_RS01845	COG5007	Belongs to the BolA IbaG family
GGC04_RS01855	COG0204	Acyl-transferase
GGC04_RS01860	COG2235	arginine
GGC04_RS01880	COG0589	response to stress
GGC04_RS01890	COG2358	TRAP transporter, solute receptor (TAXI family
GGC04_RS01895	COG1438	arginine binding
GGC04_RS01900	COG0039	L-malate dehydrogenase activity
GGC04_RS01910	COG0251	oxidation-reduction process
GGC04_RS01915	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
GGC04_RS01930	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
GGC04_RS01935	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GGC04_RS01945	COG0564	pseudouridine synthase activity
GGC04_RS01950	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GGC04_RS01960	COG4269	membrane
GGC04_RS01970	COG0525	valine-tRNA ligase activity
GGC04_RS01975	COG2927	DNA polymerase III (CHI subunit)
GGC04_RS01985	COG0795	lipopolysaccharide-transporting ATPase activity
GGC04_RS01990	COG0795	lipopolysaccharide-transporting ATPase activity
GGC04_RS01995	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GGC04_RS02000	COG1546	Belongs to the CinA family
GGC04_RS02005	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GGC04_RS02010	COG2137	regulation of response to DNA damage stimulus
GGC04_RS02020	COG0527	aspartate kinase activity
GGC04_RS02070	COG3630	sodium ion export across plasma membrane
GGC04_RS02075	COG5016	pyruvate
GGC04_RS02075	COG0511	ligase activity, forming carbon-carbon bonds
GGC04_RS02080	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
GGC04_RS02090	COG1238	metal cluster binding
GGC04_RS02095	COG0612	Peptidase, M16
GGC04_RS02100	COG2918	glutathione biosynthetic process
GGC04_RS02110	COG1854	S-ribosylhomocysteine lyase activity
GGC04_RS02125	COG0582	viral genome integration into host DNA
GGC04_RS02155	COG0328	RNA-DNA hybrid ribonuclease activity
GGC04_RS02195	COG5001	Diguanylate cyclase
GGC04_RS02195	COG4251	negative regulation of phosphorylation
GGC04_RS02195	COG3706	GGDEF domain
GGC04_RS02195	COG2203	Gaf domain
GGC04_RS02205	COG1879	ABC-type sugar transport system periplasmic component
GGC04_RS02210	COG0840	transmembrane signaling receptor activity
GGC04_RS02225	COG0840	transmembrane signaling receptor activity
GGC04_RS02230	COG5001	Diguanylate cyclase
GGC04_RS02230	COG4251	negative regulation of phosphorylation
GGC04_RS02230	COG3706	GGDEF domain
GGC04_RS02230	COG2203	Gaf domain
GGC04_RS02255	COG0640	Transcriptional regulator
GGC04_RS02300	COG2003	Belongs to the UPF0758 family
GGC04_RS02310	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
GGC04_RS02335	COG3437	response regulator, receiver
GGC04_RS02400	COG0473	3-isopropylmalate dehydrogenase activity
GGC04_RS02405	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GGC04_RS02425	COG0583	DNA-binding transcription factor activity
GGC04_RS02430	COG1022	Amp-dependent synthetase and ligase
GGC04_RS02435	COG0028	Belongs to the TPP enzyme family
GGC04_RS02440	COG0440	acetolactate synthase activity
GGC04_RS02445	COG0584	glycerophosphoryl diester phosphodiesterase
GGC04_RS02450	COG2271	Major facilitator Superfamily
GGC04_RS02455	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GGC04_RS02465	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GGC04_RS02475	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
GGC04_RS02480	COG3079	Belongs to the UPF0149 family
GGC04_RS02485	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GGC04_RS02490	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GGC04_RS02515	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GGC04_RS02520	COG1595	DNA-templated transcription, initiation
GGC04_RS02535	COG3086	response to oxidative stress
GGC04_RS02540	COG0481	GTPase activity
GGC04_RS02550	COG0571	ribonuclease III activity
GGC04_RS02555	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GGC04_RS02560	COG1381	Involved in DNA repair and RecF pathway recombination
GGC04_RS02565	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
GGC04_RS02570	COG0736	holo-[acyl-carrier-protein] synthase activity
GGC04_RS02575	COG3850	Histidine kinase
GGC04_RS02575	COG4999	Histidine kinase
GGC04_RS02575	COG3437	response regulator, receiver
GGC04_RS02575	COG2205	protein histidine kinase activity
GGC04_RS02580	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GGC04_RS02585	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GGC04_RS02590	COG3956	TIGRFAM MazG family protein
GGC04_RS02600	COG0148	phosphopyruvate hydratase activity
GGC04_RS02605	COG0617	tRNA 3'-terminal CCA addition
GGC04_RS02610	COG3409	Peptidoglycan-binding domain 1 protein
GGC04_RS02610	COG3267	Type II secretory pathway component ExeA
GGC04_RS02620	COG4991	sh3 domain protein
GGC04_RS02625	COG0306	phosphate transporter
GGC04_RS02630	COG1392	Phosphate transport regulator
GGC04_RS02635	COG3025	triphosphatase activity
GGC04_RS02640	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GGC04_RS02650	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
GGC04_RS02655	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
GGC04_RS02655	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
GGC04_RS02665	COG0745	RESPONSE REGULATOR receiver
GGC04_RS02680	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GGC04_RS02700	COG0083	homoserine kinase activity
GGC04_RS02705	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GGC04_RS02710	COG2860	membrane
GGC04_RS02715	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GGC04_RS02720	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
GGC04_RS02730	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GGC04_RS02745	COG1846	Transcriptional regulator
GGC04_RS02750	COG0534	Mate efflux family protein
GGC04_RS02755	COG2204	response regulator
GGC04_RS02765	COG0667	Aldo Keto reductase
GGC04_RS02775	COG3066	DNA modification
GGC04_RS02780	COG0494	nUDIX hydrolase
GGC04_RS02790	COG0730	response to heat
GGC04_RS02795	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GGC04_RS02800	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GGC04_RS02805	COG1283	sodium-dependent phosphate transmembrane transporter activity
GGC04_RS02810	COG0583	DNA-binding transcription factor activity
GGC04_RS02815	COG0640	Transcriptional regulator
GGC04_RS02820	COG0268	Binds directly to 16S ribosomal RNA
GGC04_RS02825	COG0728	peptidoglycan biosynthetic process
GGC04_RS02830	COG0196	riboflavin kinase activity
GGC04_RS02845	COG1047	Peptidyl-prolyl cis-trans
GGC04_RS02850	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GGC04_RS02855	COG1966	Carbon starvation protein
GGC04_RS02865	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GGC04_RS02870	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
GGC04_RS02875	COG2971	BadF BadG BcrA BcrD
GGC04_RS02885	COG1737	Transcriptional regulator
GGC04_RS02895	COG3279	Response regulator of the LytR AlgR family
GGC04_RS02900	COG3275	phosphorelay sensor kinase activity
GGC04_RS02905	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GGC04_RS02910	COG0287	Prephenate dehydrogenase
GGC04_RS02910	COG1605	Chorismate mutase
GGC04_RS02915	COG0739	heme binding
GGC04_RS02925	COG0488	(ABC) transporter
GGC04_RS02930	COG0741	lytic transglycosylase activity
GGC04_RS02935	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
GGC04_RS02940	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
GGC04_RS02945	COG5001	Diguanylate cyclase
GGC04_RS02950	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GGC04_RS02955	COG0077	Prephenate dehydratase
GGC04_RS02955	COG1605	Chorismate mutase
GGC04_RS02960	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GGC04_RS02965	COG0741	lytic transglycosylase activity
GGC04_RS02970	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GGC04_RS02975	COG0564	pseudouridine synthase activity
GGC04_RS02985	COG0542	response to heat
GGC04_RS03030	COG0483	inositol monophosphate 1-phosphatase activity
GGC04_RS03040	COG1959	2 iron, 2 sulfur cluster binding
GGC04_RS03050	COG0822	iron-sulfur transferase activity
GGC04_RS03070	COG0633	Ferredoxin
GGC04_RS03075	COG2975	iron-sulfur cluster assembly
GGC04_RS03080	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GGC04_RS03090	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GGC04_RS03095	COG0583	DNA-binding transcription factor activity
GGC04_RS03105	COG0583	DNA-binding transcription factor activity
GGC04_RS03110	COG1022	Amp-dependent synthetase and ligase
GGC04_RS03115	COG2169	Transcriptional regulator
GGC04_RS03140	COG4964	Belongs to the GSP D family
GGC04_RS03190	COG2169	Transcriptional regulator
GGC04_RS03195	COG1486	melibiose metabolic process
GGC04_RS03200	COG2211	Major facilitator Superfamily
GGC04_RS03210	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
GGC04_RS03210	COG3408	Glycogen debranching enzyme
GGC04_RS03225	COG1309	transcriptional regulator
GGC04_RS03230	COG0531	amino acid
GGC04_RS03235	COG2731	YhcH YjgK YiaL family protein
GGC04_RS03240	COG3250	beta-galactosidase activity
GGC04_RS03245	COG1609	Transcriptional regulator
GGC04_RS03250	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GGC04_RS03255	COG1085	galactose-1-phosphate uridylyltransferase
GGC04_RS03265	COG2017	converts alpha-aldose to the beta-anomer
GGC04_RS03275	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GGC04_RS03285	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GGC04_RS03285	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GGC04_RS03285	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GGC04_RS03290	COG2207	Transcriptional regulator
GGC04_RS03300	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GGC04_RS03310	COG2171	N-acyltransferase activity
GGC04_RS03315	COG0450	alkyl hydroperoxide reductase
GGC04_RS03320	COG0583	DNA-binding transcription factor activity
GGC04_RS03325	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GGC04_RS03350	COG0517	IMP dehydrogenase activity
GGC04_RS03355	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GGC04_RS03365	COG1862	Preprotein translocase
GGC04_RS03370	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GGC04_RS03375	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GGC04_RS03390	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
GGC04_RS03395	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GGC04_RS03400	COG0826	peptidase U32
GGC04_RS03410	COG0745	RESPONSE REGULATOR receiver
GGC04_RS03415	COG5002	protein histidine kinase activity
GGC04_RS03425	COG0248	Ppx GppA phosphatase
GGC04_RS03430	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GGC04_RS03435	COG0573	inorganic phosphate transmembrane transporter activity
GGC04_RS03440	COG0581	inorganic phosphate transmembrane transporter activity
GGC04_RS03445	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GGC04_RS03450	COG0704	Plays a role in the regulation of phosphate uptake
GGC04_RS03465	COG3141	response to X-ray
GGC04_RS03470	COG1309	transcriptional regulator
GGC04_RS03475	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GGC04_RS03495	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
GGC04_RS03500	COG1074	ATP-dependent DNA helicase activity
GGC04_RS03505	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GGC04_RS03525	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
GGC04_RS03530	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GGC04_RS03535	COG2166	iron-sulfur cluster assembly
GGC04_RS03545	COG1426	Protein conserved in bacteria
GGC04_RS03550	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GGC04_RS03555	COG0124	histidyl-tRNA synthetase
GGC04_RS03560	COG2976	Protein conserved in bacteria
GGC04_RS03565	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GGC04_RS03570	COG1160	GTP binding
GGC04_RS03580	COG2199	diguanylate cyclase activity
GGC04_RS03580	COG2203	Gaf domain
GGC04_RS03595	COG0516	GMP reductase activity
GGC04_RS03595	COG0517	IMP dehydrogenase activity
GGC04_RS03610	COG1584	GPR1 FUN34 yaaH family protein
GGC04_RS03615	COG1115	amino acid carrier protein
GGC04_RS03620	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GGC04_RS03640	COG2873	o-acetylhomoserine
GGC04_RS03645	COG0835	chemotaxis
GGC04_RS03645	COG0784	Response regulator, receiver
GGC04_RS03650	COG0204	Acyl-transferase
GGC04_RS03670	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GGC04_RS03675	COG0668	transmembrane transport
GGC04_RS03700	COG2867	negative regulation of translational initiation
GGC04_RS03705	COG2914	Belongs to the UPF0125 (RnfH) family
GGC04_RS03710	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GGC04_RS03715	COG0497	DNA recombination
GGC04_RS03720	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GGC04_RS03725	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GGC04_RS03730	COG1301	dicarboxylic acid transport
GGC04_RS03735	COG0443	Heat shock 70 kDa protein
GGC04_RS03750	COG4970	Tfp pilus assembly protein FimT
GGC04_RS03770	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
GGC04_RS03780	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
GGC04_RS03785	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GGC04_RS03785	COG0047	phosphoribosylformylglycinamidine synthase activity
GGC04_RS03810	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GGC04_RS03815	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GGC04_RS03820	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GGC04_RS03825	COG1187	pseudouridine synthase activity
GGC04_RS03830	COG2840	Smr protein MutS2
GGC04_RS03855	COG3104	oligopeptide transport
GGC04_RS03860	COG0367	asparagine synthase
GGC04_RS03865	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GGC04_RS03865	COG4651	solute:proton antiporter activity
GGC04_RS03870	COG1846	Transcriptional regulator
GGC04_RS03870	COG1940	carbohydrate kinase activity
GGC04_RS03875	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GGC04_RS03880	COG2190	(PTS) system
GGC04_RS03880	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GGC04_RS03880	COG1263	PTS System
GGC04_RS03910	COG0596	Alpha beta hydrolase
GGC04_RS03915	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
GGC04_RS03920	COG0033	Phosphoglucomutase
GGC04_RS03930	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GGC04_RS03945	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
GGC04_RS03950	COG1053	succinate dehydrogenase
GGC04_RS03955	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GGC04_RS03960	COG0567	Dehydrogenase, E1 component
GGC04_RS03965	COG0508	dehydrogenase complex catalyzes the overall conversion of
GGC04_RS04005	COG3098	single-species biofilm formation
GGC04_RS04010	COG0564	pseudouridine synthase activity
GGC04_RS04020	COG0142	geranyltranstransferase activity
GGC04_RS04025	COG1722	exodeoxyribonuclease VII activity
GGC04_RS04030	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GGC04_RS04040	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GGC04_RS04040	COG0301	tRNA thio-modification
GGC04_RS04045	COG0583	DNA-binding transcription factor activity
GGC04_RS04060	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
GGC04_RS04070	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GGC04_RS04075	COG1611	Belongs to the LOG family
GGC04_RS04090	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GGC04_RS04090	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GGC04_RS04100	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
GGC04_RS04115	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GGC04_RS04120	COG1393	Belongs to the ArsC family
GGC04_RS04145	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
GGC04_RS04150	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
GGC04_RS04155	COG0437	4 iron, 4 sulfur cluster binding
GGC04_RS04160	COG3301	Polysulphide reductase, NrfD
GGC04_RS04165	COG1138	Cytochrome C-type biogenesis protein
GGC04_RS04170	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GGC04_RS04175	COG3088	subunit of a heme lyase
GGC04_RS04175	COG4235	cytochrome complex assembly
GGC04_RS04185	COG2837	iron assimilation
GGC04_RS04200	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GGC04_RS04210	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
GGC04_RS04220	COG1516	flagellar protein fliS
GGC04_RS04240	COG1677	Flagellar hook-basal body complex protein FliE
GGC04_RS04250	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GGC04_RS04300	COG1987	bacterial-type flagellum assembly
GGC04_RS04305	COG1684	flagellar biosynthetic protein fliR
GGC04_RS04320	COG2890	protein-(glutamine-N5) methyltransferase activity
GGC04_RS04325	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GGC04_RS04335	COG2860	membrane
GGC04_RS04340	COG3101	peptidyl-lysine hydroxylation
GGC04_RS04370	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GGC04_RS04375	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GGC04_RS04380	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GGC04_RS04390	COG0101	tRNA pseudouridine synthase activity
GGC04_RS04395	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GGC04_RS04400	COG0285	dihydrofolate synthase activity
GGC04_RS04405	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
GGC04_RS04410	COG1286	toxin biosynthetic process
GGC04_RS04415	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GGC04_RS04420	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GGC04_RS04425	COG1121	(ABC) transporter
GGC04_RS04430	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
GGC04_RS04435	COG4977	sequence-specific DNA binding
GGC04_RS04440	COG1918	ferrous iron import across plasma membrane
GGC04_RS04445	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
GGC04_RS04460	COG0018	arginyl-trna synthetase
GGC04_RS04465	COG3102	Protein conserved in bacteria
GGC04_RS04470	COG1025	Belongs to the peptidase M16 family
GGC04_RS04475	COG2062	phosphohistidine phosphatase, SixA
GGC04_RS04505	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
GGC04_RS04510	COG2198	Histidine kinase
GGC04_RS04510	COG0784	Response regulator, receiver
GGC04_RS04510	COG0643	Histidine kinase
GGC04_RS04515	COG2201	protein-glutamate methylesterase activity
GGC04_RS04520	COG1192	Involved in chromosome partitioning
GGC04_RS04530	COG0835	chemotaxis
GGC04_RS04540	COG4133	protoheme IX ABC transporter activity
GGC04_RS04545	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GGC04_RS04550	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GGC04_RS04555	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GGC04_RS04565	COG1138	Cytochrome C-type biogenesis protein
GGC04_RS04570	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GGC04_RS04575	COG3088	subunit of a heme lyase
GGC04_RS04575	COG4235	cytochrome complex assembly
GGC04_RS04585	COG2853	Lipoprotein
GGC04_RS04590	COG2067	long-chain fatty acid transport protein
GGC04_RS04595	COG2067	long-chain fatty acid transport protein
GGC04_RS04610	COG0183	Belongs to the thiolase family
GGC04_RS04620	COG0778	Nitroreductase
GGC04_RS04625	COG0583	DNA-binding transcription factor activity
GGC04_RS04630	COG0745	RESPONSE REGULATOR receiver
GGC04_RS04640	COG2832	Protein of unknown function (DUF454)
GGC04_RS04645	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GGC04_RS04660	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GGC04_RS04695	COG1653	transport
GGC04_RS04700	COG1175	transmembrane transport
GGC04_RS04710	COG3842	ATPase activity
GGC04_RS04715	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GGC04_RS04720	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
GGC04_RS04725	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GGC04_RS04735	COG2204	response regulator
GGC04_RS04760	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GGC04_RS04765	COG0776	regulation of translation
GGC04_RS04770	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GGC04_RS04775	COG1555	photosystem II stabilization
GGC04_RS04785	COG0539	negative regulation of cytoplasmic translation
GGC04_RS04795	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
GGC04_RS04800	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
GGC04_RS04805	COG0284	orotidine-5'-phosphate decarboxylase activity
GGC04_RS04840	COG4120	Belongs to the binding-protein-dependent transport system permease family
GGC04_RS04850	COG3706	GGDEF domain
GGC04_RS04855	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GGC04_RS04875	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GGC04_RS04880	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GGC04_RS04890	COG0252	asparaginase activity
GGC04_RS04895	COG0616	signal peptide processing
GGC04_RS04900	COG1902	pentaerythritol trinitrate reductase activity
GGC04_RS04900	COG0446	pyridine nucleotide-disulphide oxidoreductase
GGC04_RS04905	COG0788	formyltetrahydrofolate deformylase activity
GGC04_RS04915	COG1199	ATP-dependent helicase activity
GGC04_RS04920	COG1214	PFAM Peptidase M22, glycoprotease
GGC04_RS04935	COG2267	carboxylic ester hydrolase activity
GGC04_RS04940	COG0318	PFAM AMP-dependent synthetase and ligase
GGC04_RS04945	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
GGC04_RS04950	COG0659	secondary active sulfate transmembrane transporter activity
GGC04_RS04955	COG1530	ribonuclease E activity
GGC04_RS04960	COG0564	pseudouridine synthase activity
GGC04_RS04965	COG0424	maF-like protein
GGC04_RS04970	COG1399	metal-binding, possibly nucleic acid-binding protein
GGC04_RS04975	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GGC04_RS04985	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GGC04_RS05010	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GGC04_RS05015	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GGC04_RS05020	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GGC04_RS05025	COG0470	DNA polymerase III
GGC04_RS05030	COG0084	hydrolase, TatD family'
GGC04_RS05035	COG1263	PTS System
GGC04_RS05035	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GGC04_RS05055	COG0733	neurotransmitter:sodium symporter activity
GGC04_RS05070	COG4667	esterase of the alpha-beta hydrolase superfamily
GGC04_RS05075	COG0469	pyruvate kinase activity
GGC04_RS05080	COG1940	carbohydrate kinase activity
GGC04_RS05085	COG0784	Response regulator, receiver
GGC04_RS05085	COG0835	chemotaxis
GGC04_RS05105	COG1028	Short-chain dehydrogenase reductase Sdr
GGC04_RS05110	COG0616	signal peptide processing
GGC04_RS05115	COG0513	Belongs to the DEAD box helicase family
GGC04_RS05130	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GGC04_RS05135	COG0232	Belongs to the dGTPase family. Type 2 subfamily
GGC04_RS05145	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
GGC04_RS05150	COG0436	Aminotransferase
GGC04_RS05155	COG1169	isochorismate synthase
GGC04_RS05160	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
GGC04_RS05165	COG0596	Alpha beta hydrolase
GGC04_RS05185	COG2855	membrane
GGC04_RS05190	COG0477	Major facilitator Superfamily
GGC04_RS05215	COG1522	sequence-specific DNA binding
GGC04_RS05230	COG1946	Acyl-CoA thioesterase
GGC04_RS05235	COG3126	Type III secretion system lipoprotein chaperone (YscW)
GGC04_RS05250	COG3706	GGDEF domain
GGC04_RS05295	COG1414	Transcriptional regulator
GGC04_RS05300	COG0280	phosphate acetyltransferase
GGC04_RS05305	COG0730	response to heat
GGC04_RS05325	COG2855	membrane
GGC04_RS05340	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GGC04_RS05345	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GGC04_RS05350	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
GGC04_RS05355	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
GGC04_RS05355	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GGC04_RS05370	COG1472	Belongs to the glycosyl hydrolase 3 family
GGC04_RS05375	COG3876	Protein conserved in bacteria
GGC04_RS05385	COG1215	transferase activity, transferring glycosyl groups
GGC04_RS05405	COG1770	oligopeptidase
GGC04_RS05415	COG3227	Zinc metalloprotease (Elastase)
GGC04_RS05425	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GGC04_RS05435	COG0577	efflux transmembrane transporter activity
GGC04_RS05445	COG0577	efflux transmembrane transporter activity
GGC04_RS05445	COG1136	(ABC) transporter
GGC04_RS05465	COG0330	HflC and HflK could
GGC04_RS05475	COG0840	transmembrane signaling receptor activity
GGC04_RS05480	COG1404	Belongs to the peptidase S8 family
GGC04_RS05510	COG2067	long-chain fatty acid transport protein
GGC04_RS05525	COG0601	transmembrane transport
GGC04_RS05530	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GGC04_RS05535	COG0444	Belongs to the ABC transporter superfamily
GGC04_RS05545	COG0435	Glutathione S-transferase
GGC04_RS05555	COG0857	belongs to the CobB CobQ family
GGC04_RS05555	COG0280	phosphate acetyltransferase
GGC04_RS05560	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GGC04_RS05565	COG3092	negative regulation of chromosome organization
GGC04_RS05570	COG0686	Belongs to the AlaDH PNT family
GGC04_RS05580	COG1674	ftsk spoiiie
GGC04_RS05590	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GGC04_RS05595	COG2186	Transcriptional regulator
GGC04_RS05610	COG0537	adenosine 5'-monophosphoramidase activity
GGC04_RS05640	COG1252	NADH dehydrogenase
GGC04_RS05665	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GGC04_RS05675	COG4591	ABC-type transport system involved in lipoprotein release permease component
GGC04_RS05680	COG1136	(ABC) transporter
GGC04_RS05685	COG4591	ABC-type transport system involved in lipoprotein release permease component
GGC04_RS05695	COG0658	competence protein
GGC04_RS05695	COG2333	competence protein COMEC
GGC04_RS05700	COG1132	(ABC) transporter
GGC04_RS05710	COG2835	tetraacyldisaccharide 4'-kinase activity
GGC04_RS05715	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
GGC04_RS05720	COG2719	SpoVR family
GGC04_RS05725	COG2718	Belongs to the UPF0229 family
GGC04_RS05730	COG2766	serine protein kinase
GGC04_RS05735	COG3713	MltA-interacting MipA family protein
GGC04_RS05740	COG3013	Belongs to the UPF0304 family
GGC04_RS05750	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GGC04_RS05765	COG1882	Formate acetyltransferase
GGC04_RS05800	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GGC04_RS05935	COG3772	lysozyme
GGC04_RS05950	COG4695	Portal protein
GGC04_RS05990	COG4386	tail sheath protein
GGC04_RS06025	COG3646	Phage regulatory protein
GGC04_RS06045	COG1012	belongs to the aldehyde dehydrogenase family
GGC04_RS06045	COG1454	alcohol dehydrogenase
GGC04_RS06050	COG1737	Transcriptional regulator
GGC04_RS06055	COG0076	glutamate decarboxylase activity
GGC04_RS06065	COG2431	L-lysine efflux transmembrane transporter activity
GGC04_RS06075	COG3070	regulator of competence-specific genes
GGC04_RS06090	COG4191	Histidine kinase
GGC04_RS06090	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GGC04_RS06100	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GGC04_RS06110	COG1032	radical SAM domain protein
GGC04_RS06135	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GGC04_RS06140	COG1764	response to oxidative stress
GGC04_RS06145	COG1846	Transcriptional regulator
GGC04_RS06155	COG0583	DNA-binding transcription factor activity
GGC04_RS06165	COG0673	inositol 2-dehydrogenase activity
GGC04_RS06170	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GGC04_RS06190	COG0840	transmembrane signaling receptor activity
GGC04_RS06195	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GGC04_RS06210	COG3152	Membrane
GGC04_RS06255	COG1858	cytochrome C peroxidase
GGC04_RS06270	COG0443	Heat shock 70 kDa protein
GGC04_RS06320	COG1643	Atp-dependent helicase
GGC04_RS06330	COG1301	dicarboxylic acid transport
GGC04_RS06335	COG0159	tryptophan synthase activity
GGC04_RS06345	COG0135	phosphoribosylanthranilate isomerase activity
GGC04_RS06345	COG0134	indole-3-glycerol-phosphate synthase activity
GGC04_RS06350	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GGC04_RS06355	COG0512	Glutamine amidotransferase of anthranilate synthase
GGC04_RS06360	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GGC04_RS06370	COG0613	PHP domain protein
GGC04_RS06375	COG0009	L-threonylcarbamoyladenylate synthase
GGC04_RS06390	COG1187	pseudouridine synthase activity
GGC04_RS06395	COG0384	phenazine biosynthesis protein PhzF
GGC04_RS06405	COG2814	Major facilitator Superfamily
GGC04_RS06410	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GGC04_RS06415	COG4988	ABC transporter
GGC04_RS06420	COG0492	ferredoxin-NADP+ reductase activity
GGC04_RS06435	COG2175	clavaminate synthase activity
GGC04_RS06450	COG0612	Peptidase, M16
GGC04_RS06460	COG2949	membrane
GGC04_RS06470	COG0281	malic enzyme
GGC04_RS06475	COG1643	Atp-dependent helicase
GGC04_RS06490	COG1448	Aminotransferase
GGC04_RS06495	COG3437	response regulator, receiver
GGC04_RS06495	COG2770	Histidine kinase
GGC04_RS06505	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GGC04_RS06520	COG0017	Asparaginyl-tRNA synthetase
GGC04_RS06535	COG0814	amino acid
GGC04_RS06545	COG1760	l-serine dehydratase
GGC04_RS06550	COG0814	amino acid
GGC04_RS06555	COG0494	nUDIX hydrolase
GGC04_RS06565	COG2205	protein histidine kinase activity
GGC04_RS06565	COG0784	Response regulator, receiver
GGC04_RS06585	COG3106	COG3106 Predicted ATPase
GGC04_RS06600	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GGC04_RS06620	COG3706	GGDEF domain
GGC04_RS06625	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GGC04_RS06650	COG2989	Protein conserved in bacteria
GGC04_RS06655	COG3108	Peptidase M15
GGC04_RS06660	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GGC04_RS06675	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
GGC04_RS06710	COG4667	esterase of the alpha-beta hydrolase superfamily
GGC04_RS06715	COG0783	Belongs to the Dps family
GGC04_RS06725	COG0531	amino acid
GGC04_RS06730	COG2962	Rard protein
GGC04_RS06800	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GGC04_RS06940	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GGC04_RS06980	COG0546	phosphoglycolate phosphatase activity
GGC04_RS06985	COG4628	conserved protein (DUF2132)
GGC04_RS06995	COG0456	acetyltransferase
GGC04_RS07005	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GGC04_RS07015	COG0730	response to heat
GGC04_RS07025	COG1028	Short-chain dehydrogenase reductase Sdr
GGC04_RS07035	COG2824	Alkylphosphonate utilization operon protein PhnA
GGC04_RS07050	COG0456	acetyltransferase
GGC04_RS07070	COG3040	lipid binding
GGC04_RS07085	COG3122	Protein conserved in bacteria
GGC04_RS07140	COG0454	-acetyltransferase
GGC04_RS07145	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GGC04_RS07170	COG0456	acetyltransferase
GGC04_RS07190	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GGC04_RS07205	COG2195	Cleaves the N-terminal amino acid of tripeptides
GGC04_RS07215	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
GGC04_RS07225	COG0625	glutathione transferase activity
GGC04_RS07240	COG2885	chlorophyll binding
GGC04_RS07255	COG0277	FAD linked oxidase domain protein
GGC04_RS07255	COG0247	lactate metabolic process
GGC04_RS07270	COG2986	histidine ammonia-lyase
GGC04_RS07280	COG0010	Belongs to the arginase family
GGC04_RS07285	COG1228	amidohydrolase
GGC04_RS07290	COG2188	Transcriptional regulator
GGC04_RS07295	COG4326	sporulation control protein
GGC04_RS07315	COG0500	methyltransferase
GGC04_RS07320	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
GGC04_RS07330	COG0295	cytidine deaminase activity
GGC04_RS07335	COG1346	cytolysis
GGC04_RS07340	COG1380	Effector of murein hydrolase LrgA
GGC04_RS07345	COG2925	Exonuclease
GGC04_RS07350	COG1823	symporter activity
GGC04_RS07355	COG0702	epimerase
GGC04_RS07360	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GGC04_RS07365	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
GGC04_RS07370	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
GGC04_RS07380	COG0406	alpha-ribazole phosphatase activity
GGC04_RS07400	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
GGC04_RS07425	COG2814	Major facilitator Superfamily
GGC04_RS07435	COG1119	ATPase activity
GGC04_RS07445	COG0784	Response regulator, receiver
GGC04_RS07445	COG5002	protein histidine kinase activity
GGC04_RS07455	COG1451	nucleotide metabolic process
GGC04_RS07470	COG3063	Type IV pilus biogenesis stability protein PilW
GGC04_RS07475	COG0596	Alpha beta hydrolase
GGC04_RS07475	COG0508	dehydrogenase complex catalyzes the overall conversion of
GGC04_RS07480	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
GGC04_RS07495	COG4943	cyclic-guanylate-specific phosphodiesterase activity
GGC04_RS07510	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GGC04_RS07535	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GGC04_RS07540	COG0515	serine threonine protein kinase
GGC04_RS07655	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
GGC04_RS07660	COG0372	Belongs to the citrate synthase family
GGC04_RS07670	COG2828	Protein conserved in bacteria
GGC04_RS07690	COG0561	phosphatase activity
GGC04_RS07695	COG0602	queuosine metabolic process
GGC04_RS07730	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GGC04_RS07735	COG0840	transmembrane signaling receptor activity
GGC04_RS07740	COG1254	Belongs to the acylphosphatase family
GGC04_RS07745	COG2920	part of a sulfur-relay system
GGC04_RS07750	COG0670	Belongs to the BI1 family
GGC04_RS07755	COG1126	abc transporter atp-binding protein
GGC04_RS07760	COG0765	amino acid transport
GGC04_RS07765	COG4597	amino acid ABC transporter
GGC04_RS07770	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GGC04_RS07785	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GGC04_RS07810	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GGC04_RS07810	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
GGC04_RS07815	COG3008	intermembrane lipid transfer
GGC04_RS07820	COG2995	paraquat-inducible protein a
GGC04_RS07825	COG1132	(ABC) transporter
GGC04_RS07830	COG1956	GAF domain-containing protein
GGC04_RS07835	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
GGC04_RS07850	COG0308	aminopeptidase N
GGC04_RS07865	COG0167	dihydroorotate dehydrogenase activity
GGC04_RS07875	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GGC04_RS07875	COG0116	Belongs to the methyltransferase superfamily
GGC04_RS07885	COG0488	(ABC) transporter
GGC04_RS07900	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GGC04_RS07905	COG1067	ATP-dependent peptidase activity
GGC04_RS07960	COG0789	Transcriptional regulator
GGC04_RS07990	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GGC04_RS08010	COG0840	transmembrane signaling receptor activity
GGC04_RS08160	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GGC04_RS08190	COG1132	(ABC) transporter
GGC04_RS08305	COG3278	Belongs to the heme-copper respiratory oxidase family
GGC04_RS08320	COG2010	Cytochrome c
GGC04_RS08330	COG2217	Heavy metal translocating P-type atpase
GGC04_RS08345	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GGC04_RS08350	COG0589	response to stress
GGC04_RS08375	COG3842	ATPase activity
GGC04_RS08385	COG1177	transmembrane transport
GGC04_RS08390	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GGC04_RS08395	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GGC04_RS08400	COG2199	diguanylate cyclase activity
GGC04_RS08405	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GGC04_RS08410	COG0004	ammonium transporteR
GGC04_RS08425	COG0437	4 iron, 4 sulfur cluster binding
GGC04_RS08430	COG0243	molybdopterin cofactor binding
GGC04_RS08430	COG3383	formate dehydrogenase (NAD+) activity
GGC04_RS08460	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GGC04_RS08470	COG3038	cytochrome b561
GGC04_RS08495	COG0583	DNA-binding transcription factor activity
GGC04_RS08505	COG0583	DNA-binding transcription factor activity
GGC04_RS08510	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
GGC04_RS08530	COG0069	glutamate synthase activity
GGC04_RS08535	COG1028	Short-chain dehydrogenase reductase Sdr
GGC04_RS08550	COG0488	(ABC) transporter
GGC04_RS08560	COG1595	DNA-templated transcription, initiation
GGC04_RS08575	COG3852	Histidine kinase
GGC04_RS08590	COG4662	Binding-protein-dependent transport system inner membrane component
GGC04_RS08595	COG3842	ATPase activity
GGC04_RS08600	COG0746	molybdenum cofactor guanylyltransferase activity
GGC04_RS08605	COG0303	'Molybdopterin
GGC04_RS08635	COG1940	carbohydrate kinase activity
GGC04_RS08640	COG3148	PFAM DTW domain containing protein
GGC04_RS08650	COG0840	transmembrane signaling receptor activity
GGC04_RS08655	COG0791	NLP P60 protein
GGC04_RS08665	COG3001	Fructosamine kinase
GGC04_RS08675	COG0307	riboflavin synthase, alpha
GGC04_RS08680	COG0534	Mate efflux family protein
GGC04_RS08725	COG2204	response regulator
GGC04_RS08735	COG0438	transferase activity, transferring glycosyl groups
GGC04_RS08770	COG0297	glycogen (starch) synthase activity
GGC04_RS08780	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GGC04_RS08820	COG4774	siderophore transport
GGC04_RS08840	COG4615	Cyclic peptide transporter
GGC04_RS08850	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GGC04_RS08855	COG1120	ATPase activity
GGC04_RS08860	COG2977	Belongs to the P-Pant transferase superfamily
GGC04_RS08865	COG1929	Belongs to the glycerate kinase type-1 family
GGC04_RS08870	COG3835	regulator
GGC04_RS08880	COG2814	Major facilitator Superfamily
GGC04_RS08890	COG1288	antiporter activity
GGC04_RS08900	COG2186	Transcriptional regulator
GGC04_RS08910	COG3713	MltA-interacting MipA family protein
GGC04_RS08920	COG0745	RESPONSE REGULATOR receiver
GGC04_RS08930	COG0583	DNA-binding transcription factor activity
GGC04_RS08950	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GGC04_RS08970	COG2116	formate transmembrane transporter activity
GGC04_RS08980	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GGC04_RS08990	COG2199	diguanylate cyclase activity
GGC04_RS09010	COG4565	transcriptional regulatory protein
GGC04_RS09015	COG3290	protein histidine kinase activity
GGC04_RS09035	COG0848	biopolymer transport protein
GGC04_RS09040	COG0811	peptide transport
GGC04_RS09045	COG0811	peptide transport
GGC04_RS09055	COG4774	siderophore transport
GGC04_RS09060	COG2205	protein histidine kinase activity
GGC04_RS09065	COG0745	RESPONSE REGULATOR receiver
GGC04_RS09070	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GGC04_RS09110	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GGC04_RS09115	COG1328	CTP reductase activity
GGC04_RS09120	COG0840	transmembrane signaling receptor activity
GGC04_RS09130	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GGC04_RS09135	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GGC04_RS09140	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GGC04_RS09145	COG0633	Ferredoxin
GGC04_RS09170	COG0019	diaminopimelate decarboxylase activity
GGC04_RS09210	COG0577	efflux transmembrane transporter activity
GGC04_RS09215	COG1136	(ABC) transporter
GGC04_RS09220	COG0534	Mate efflux family protein
GGC04_RS09225	COG0702	epimerase
GGC04_RS09235	COG2814	Major facilitator Superfamily
GGC04_RS09245	COG1061	Type III restriction enzyme res subunit
GGC04_RS09285	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GGC04_RS09290	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GGC04_RS09310	COG0463	Glycosyl transferase, family 2
GGC04_RS09335	COG0455	bacterial-type flagellum organization
GGC04_RS09350	COG2188	Transcriptional regulator
GGC04_RS09355	COG1263	PTS System
GGC04_RS09355	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GGC04_RS09360	COG1621	beta-fructofuranosidase activity
GGC04_RS09370	COG0583	DNA-binding transcription factor activity
GGC04_RS09375	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GGC04_RS09410	COG4221	oxidoreductase activity
GGC04_RS09440	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GGC04_RS09445	COG0307	riboflavin synthase, alpha
GGC04_RS09495	COG0242	peptide deformylase activity
GGC04_RS09500	COG0519	Catalyzes the synthesis of GMP from XMP
GGC04_RS09515	COG4580	involved in the transport of maltose and maltodextrins
GGC04_RS09520	COG0778	Nitroreductase
GGC04_RS09575	COG5001	Diguanylate cyclase
GGC04_RS09575	COG3300	MHYT domain
GGC04_RS09600	COG1115	amino acid carrier protein
GGC04_RS09605	COG1280	lysine exporter protein (LysE YggA)
GGC04_RS09610	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
GGC04_RS09615	COG0352	thiamine-phosphate diphosphorylase activity
GGC04_RS09620	COG0583	DNA-binding transcription factor activity
GGC04_RS09645	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GGC04_RS09655	COG1012	belongs to the aldehyde dehydrogenase family
GGC04_RS09665	COG0583	DNA-binding transcription factor activity
GGC04_RS09705	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GGC04_RS09715	COG1609	Transcriptional regulator
GGC04_RS09730	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GGC04_RS09735	COG1609	Transcriptional regulator
GGC04_RS09745	COG0642	Histidine kinase
GGC04_RS09750	COG0745	RESPONSE REGULATOR receiver
GGC04_RS09770	COG1858	cytochrome C peroxidase
GGC04_RS09780	COG0784	Response regulator, receiver
GGC04_RS09780	COG2205	protein histidine kinase activity
GGC04_RS09785	COG0488	(ABC) transporter
GGC04_RS09790	COG3437	response regulator, receiver
GGC04_RS09800	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GGC04_RS09810	COG2223	nitrite transmembrane transporter activity
GGC04_RS09815	COG1216	Glycosyl transferase, family 2
GGC04_RS09825	COG0673	inositol 2-dehydrogenase activity
GGC04_RS09830	COG3718	enzyme involved in inositol metabolism
GGC04_RS09855	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GGC04_RS09860	COG0673	inositol 2-dehydrogenase activity
GGC04_RS09865	COG3962	Belongs to the TPP enzyme family
GGC04_RS09875	COG0477	Major facilitator Superfamily
GGC04_RS09875	COG2814	Major facilitator Superfamily
GGC04_RS09895	COG0183	Belongs to the thiolase family
GGC04_RS09900	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GGC04_RS09940	COG3962	Belongs to the TPP enzyme family
GGC04_RS09945	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GGC04_RS09955	COG1129	ABC transporter
GGC04_RS09960	COG4211	Belongs to the binding-protein-dependent transport system permease family
GGC04_RS09970	COG0277	FAD linked oxidase domain protein
GGC04_RS09980	COG0583	DNA-binding transcription factor activity
GGC04_RS10000	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GGC04_RS10005	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
GGC04_RS10025	COG1621	beta-fructofuranosidase activity
GGC04_RS10040	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GGC04_RS10040	COG1263	PTS System
GGC04_RS10050	COG1335	isochorismatase
GGC04_RS10055	COG1741	Belongs to the pirin family
GGC04_RS10100	COG4974	Belongs to the 'phage' integrase family
GGC04_RS10110	COG1733	regulation of RNA biosynthetic process
GGC04_RS10120	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
GGC04_RS10140	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GGC04_RS10145	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GGC04_RS10145	COG0072	phenylalanine-tRNA ligase activity
GGC04_RS10155	COG3706	GGDEF domain
GGC04_RS10180	COG2133	pyrroloquinoline quinone binding
GGC04_RS10190	COG1902	pentaerythritol trinitrate reductase activity
GGC04_RS10220	COG0322	excinuclease ABC activity
GGC04_RS10225	COG2197	response regulator
GGC04_RS10240	COG0417	DNA replication proofreading
GGC04_RS10255	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GGC04_RS10265	COG0776	regulation of translation
GGC04_RS10300	COG2350	Protein conserved in bacteria
GGC04_RS10315	COG3313	Fe-S protein
GGC04_RS10325	COG4134	Bacterial extracellular solute-binding protein
GGC04_RS10330	COG4135	transport system, permease component
GGC04_RS10335	COG4136	ATPase activity
GGC04_RS10340	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GGC04_RS10345	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GGC04_RS10350	COG0564	pseudouridine synthase activity
GGC04_RS10355	COG0733	neurotransmitter:sodium symporter activity
GGC04_RS10365	COG0626	cystathionine gamma-synthase activity
GGC04_RS10370	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
GGC04_RS10375	COG5380	lipid catabolic process
GGC04_RS10380	COG2818	Glycosylase
GGC04_RS10395	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GGC04_RS10400	COG1983	PspC domain protein
GGC04_RS10410	COG1842	Phage shock protein A
GGC04_RS10415	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GGC04_RS10430	COG4171	peptide transport system, permease
GGC04_RS10440	COG4172	Belongs to the ABC transporter superfamily
GGC04_RS10455	COG1227	inorganic diphosphatase activity
GGC04_RS10465	COG0217	transcriptional regulatory protein
GGC04_RS10470	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GGC04_RS10470	COG0140	phosphoribosyl-ATP diphosphatase activity
GGC04_RS10480	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GGC04_RS10485	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GGC04_RS10490	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GGC04_RS10490	COG0131	Imidazoleglycerol-phosphate dehydratase
GGC04_RS10500	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GGC04_RS10510	COG1757	Na H antiporter
GGC04_RS10520	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GGC04_RS10530	COG0482	sulfurtransferase activity
GGC04_RS10540	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GGC04_RS10550	COG2268	Band 7 protein
GGC04_RS10560	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GGC04_RS10575	COG1028	Short-chain dehydrogenase reductase Sdr
GGC04_RS10585	COG0501	Belongs to the peptidase M48B family
GGC04_RS10590	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
GGC04_RS10595	COG1073	alpha beta
GGC04_RS10595	COG2226	methyltransferase
GGC04_RS10600	COG0156	8-amino-7-oxononanoate synthase activity
GGC04_RS10610	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GGC04_RS10625	COG1199	ATP-dependent helicase activity
GGC04_RS10630	COG0730	response to heat
GGC04_RS10645	COG2850	peptidyl-arginine hydroxylation
GGC04_RS10650	COG0840	transmembrane signaling receptor activity
GGC04_RS10655	COG0708	Exodeoxyribonuclease III
GGC04_RS10660	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GGC04_RS10665	COG1960	acyl-CoA dehydrogenase activity
GGC04_RS10680	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GGC04_RS10685	COG0463	Glycosyl transferase, family 2
GGC04_RS10690	COG0745	RESPONSE REGULATOR receiver
GGC04_RS10695	COG5002	protein histidine kinase activity
GGC04_RS10695	COG3850	Histidine kinase
GGC04_RS10710	COG1940	carbohydrate kinase activity
GGC04_RS10725	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GGC04_RS10730	COG1881	PFAM PEBP family protein
GGC04_RS10735	COG1902	pentaerythritol trinitrate reductase activity
GGC04_RS10755	COG0784	Response regulator, receiver
GGC04_RS10755	COG5002	protein histidine kinase activity
GGC04_RS10770	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
GGC04_RS10775	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GGC04_RS10780	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
GGC04_RS10785	COG2885	chlorophyll binding
GGC04_RS10790	COG0823	Involved in the tonB-independent uptake of proteins
GGC04_RS10805	COG0811	peptide transport
GGC04_RS10810	COG0824	Thioesterase
GGC04_RS10820	COG4890	Cyd operon protein YbgT
GGC04_RS10825	COG1294	oxidase, subunit
GGC04_RS10830	COG1271	oxidase subunit
GGC04_RS10835	COG2255	four-way junction helicase activity
GGC04_RS10840	COG0632	four-way junction helicase activity
GGC04_RS10845	COG0840	transmembrane signaling receptor activity
GGC04_RS10850	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
GGC04_RS10870	COG4221	oxidoreductase activity
GGC04_RS10885	COG0243	molybdopterin cofactor binding
GGC04_RS10890	COG3005	denitrification pathway
GGC04_RS10895	COG4459	periplasmic nitrate reductase
GGC04_RS10900	COG0390	transport system, permease component
GGC04_RS10905	COG2116	formate transmembrane transporter activity
GGC04_RS10930	COG0542	response to heat
GGC04_RS10935	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
GGC04_RS10940	COG1278	Cold shock
GGC04_RS10950	COG1187	pseudouridine synthase activity
GGC04_RS10960	COG1801	Protein of unknown function DUF72
GGC04_RS10970	COG0500	methyltransferase
GGC04_RS10975	COG4067	protein conserved in archaea
GGC04_RS10975	COG0189	ligase activity
GGC04_RS11005	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
GGC04_RS11010	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
GGC04_RS11020	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GGC04_RS11025	COG1434	Gram-negative-bacterium-type cell wall biogenesis
GGC04_RS11030	COG0745	RESPONSE REGULATOR receiver
GGC04_RS11045	COG3070	regulator of competence-specific genes
GGC04_RS11065	COG0297	glycogen (starch) synthase activity
GGC04_RS11070	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GGC04_RS11075	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GGC04_RS11085	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GGC04_RS11095	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
GGC04_RS11100	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
GGC04_RS11105	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GGC04_RS11110	COG1435	thymidine kinase activity
GGC04_RS11115	COG0215	cysteine-tRNA ligase activity
GGC04_RS11120	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GGC04_RS11125	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GGC04_RS11130	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
GGC04_RS11135	COG3012	SEC-C Motif Domain Protein
GGC04_RS11140	COG3139	Protein of unknown function (DUF1315)
GGC04_RS11150	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GGC04_RS11165	COG0840	transmembrane signaling receptor activity
GGC04_RS11170	COG2226	methyltransferase
GGC04_RS11185	COG1785	Belongs to the alkaline phosphatase family
GGC04_RS11205	COG0668	transmembrane transport
GGC04_RS11210	COG2983	Belongs to the UPF0260 family
GGC04_RS11225	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GGC04_RS11230	COG0583	DNA-binding transcription factor activity
GGC04_RS11235	COG2951	lytic endotransglycosylase activity
GGC04_RS11240	COG3100	YcgL domain-containing protein
GGC04_RS11245	COG0850	regulation of cytokinetic process
GGC04_RS11250	COG2894	cell division
GGC04_RS11255	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
GGC04_RS11260	COG1454	alcohol dehydrogenase
GGC04_RS11260	COG1012	belongs to the aldehyde dehydrogenase family
GGC04_RS11265	COG2095	MarC family integral membrane protein
GGC04_RS11270	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GGC04_RS11275	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GGC04_RS11280	COG1757	Na H antiporter
GGC04_RS11300	COG3081	Nucleoid-associated protein
GGC04_RS11305	COG3082	Protein of unknown function (DUF1414)
GGC04_RS11310	COG3083	sulfuric ester hydrolase activity
GGC04_RS11370	COG0123	including yeast histone deacetylase and acetoin utilization protein
GGC04_RS11380	COG1881	PFAM PEBP family protein
GGC04_RS11390	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GGC04_RS11395	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
GGC04_RS11415	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GGC04_RS11420	COG0302	gtp cyclohydrolase
GGC04_RS11420	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GGC04_RS11425	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GGC04_RS11430	COG0302	gtp cyclohydrolase
GGC04_RS11440	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
GGC04_RS11445	COG0110	maltose O-acetyltransferase activity
GGC04_RS11500	COG2982	Protein involved in outer membrane biogenesis
GGC04_RS11505	COG0572	uridine kinase
GGC04_RS11510	COG0489	protein tyrosine kinase activity
GGC04_RS11555	COG0617	tRNA 3'-terminal CCA addition
GGC04_RS11555	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GGC04_RS11555	COG0517	IMP dehydrogenase activity
GGC04_RS11565	COG3706	GGDEF domain
GGC04_RS11570	COG0314	molybdopterin synthase activity
GGC04_RS11575	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
GGC04_RS11585	COG0521	Mo-molybdopterin cofactor biosynthetic process
GGC04_RS11590	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GGC04_RS11595	COG0391	Required for morphogenesis under gluconeogenic growth conditions
GGC04_RS11600	COG2198	Histidine kinase
GGC04_RS11610	COG0556	nucleotide-excision repair
GGC04_RS11630	COG0739	heme binding
GGC04_RS11675	COG2885	chlorophyll binding
GGC04_RS11695	COG1987	bacterial-type flagellum assembly
GGC04_RS11720	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GGC04_RS11725	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
GGC04_RS11730	COG1516	flagellar protein fliS
GGC04_RS11745	COG1580	Controls the rotational direction of flagella during chemotaxis
GGC04_RS11750	COG1191	sigma factor activity
GGC04_RS11755	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GGC04_RS11760	COG1360	Flagellar Motor Protein
GGC04_RS11790	COG1706	bacterial-type flagellum-dependent cell motility
GGC04_RS11795	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
GGC04_RS11800	COG4786	Flagellar basal body rod
GGC04_RS11805	COG4787	bacterial-type flagellum-dependent cell motility
GGC04_RS11810	COG1749	Flagellar hook protein flgE
GGC04_RS11820	COG1558	bacterial-type flagellum-dependent cell motility
GGC04_RS11825	COG1815	bacterial-type flagellum-dependent cell motility
GGC04_RS11845	COG0741	lytic transglycosylase activity
GGC04_RS11845	COG1388	LysM domain
GGC04_RS11850	COG4657	Part of a membrane complex involved in electron transport
GGC04_RS11860	COG4656	Part of a membrane complex involved in electron transport
GGC04_RS11865	COG4658	electron transport chain
GGC04_RS11870	COG4659	FMN binding
GGC04_RS11875	COG4660	Part of a membrane complex involved in electron transport
GGC04_RS11880	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GGC04_RS11885	COG0346	lactoylglutathione lyase activity
GGC04_RS11905	COG2056	Na+-H+ antiporter family
GGC04_RS11910	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
GGC04_RS11920	COG2716	regulation of RNA biosynthetic process
GGC04_RS11925	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GGC04_RS11945	COG4783	chaperone-mediated protein folding
GGC04_RS11950	COG1393	Belongs to the ArsC family
GGC04_RS11975	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GGC04_RS11985	COG2877	3-deoxy-8-phosphooctulonate synthase activity
GGC04_RS11990	COG2912	Transglutaminase-like superfamily
GGC04_RS12000	COG2890	protein-(glutamine-N5) methyltransferase activity
GGC04_RS12020	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GGC04_RS12025	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GGC04_RS12035	COG0012	GTP binding
GGC04_RS12155	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GGC04_RS12165	COG3951	Flagellar rod assembly protein muramidase FlgJ
GGC04_RS12165	COG1705	Flagellar rod assembly protein muramidase FlgJ
GGC04_RS12170	COG1706	bacterial-type flagellum-dependent cell motility
GGC04_RS12175	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
GGC04_RS12185	COG4787	bacterial-type flagellum-dependent cell motility
GGC04_RS12205	COG1815	bacterial-type flagellum-dependent cell motility
GGC04_RS12210	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GGC04_RS12215	COG0784	Response regulator, receiver
GGC04_RS12215	COG0835	chemotaxis
GGC04_RS12225	COG2747	anti-sigma28 factor FlgM
GGC04_RS12265	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GGC04_RS12275	COG2194	sulfuric ester hydrolase activity
GGC04_RS12295	COG2885	chlorophyll binding
GGC04_RS12295	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
GGC04_RS12315	COG2217	Heavy metal translocating P-type atpase
GGC04_RS12315	COG2608	mercury ion transmembrane transporter activity
GGC04_RS12335	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
GGC04_RS12345	COG0326	Molecular chaperone. Has ATPase activity
GGC04_RS12350	COG3710	Transcriptional regulator
GGC04_RS12370	COG0622	Phosphoesterase
GGC04_RS12395	COG1090	epimerase
GGC04_RS12400	COG0300	oxidoreductase activity
GGC04_RS12410	COG3118	belongs to the thioredoxin family
GGC04_RS12415	COG0330	HflC and HflK could
GGC04_RS12435	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GGC04_RS12440	COG3115	cell septum assembly
GGC04_RS12445	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
GGC04_RS12450	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GGC04_RS12455	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GGC04_RS12460	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GGC04_RS12465	COG2190	(PTS) system
GGC04_RS12480	COG1702	phosphate starvation-inducible protein PhoH
GGC04_RS12485	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GGC04_RS12490	COG4535	Mg2 and Co2 transporter CorC
GGC04_RS12495	COG0815	Transfers the fatty acyl group on membrane lipoproteins
GGC04_RS12500	COG2888	peptidyl-tyrosine sulfation
GGC04_RS12505	COG0495	leucyl-tRNA aminoacylation
GGC04_RS12510	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
GGC04_RS12515	COG1466	dna polymerase III delta subunit
GGC04_RS12520	COG0799	negative regulation of ribosome biogenesis
GGC04_RS12525	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GGC04_RS12530	COG0768	penicillin binding
GGC04_RS12535	COG0772	Belongs to the SEDS family
GGC04_RS12540	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GGC04_RS12545	COG1686	Belongs to the peptidase S11 family
GGC04_RS12550	COG2921	Belongs to the UPF0250 family
GGC04_RS12560	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GGC04_RS12575	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GGC04_RS12585	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GGC04_RS12590	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GGC04_RS12600	COG0366	Alpha amylase catalytic
GGC04_RS12605	COG1263	PTS System
GGC04_RS12605	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GGC04_RS12610	COG1609	Transcriptional regulator
GGC04_RS12620	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GGC04_RS12625	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GGC04_RS12630	COG2011	ABC-type metal ion transport system permease component
GGC04_RS12635	COG1464	Belongs to the NlpA lipoprotein family
GGC04_RS12645	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
GGC04_RS12655	COG0254	rRNA binding
GGC04_RS12660	COG1720	tRNA m6t6A37 methyltransferase activity
GGC04_RS12670	COG0121	glutamine amidotransferase
GGC04_RS12675	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
GGC04_RS12680	COG1960	acyl-CoA dehydrogenase activity
GGC04_RS12695	COG0328	RNA-DNA hybrid ribonuclease activity
GGC04_RS12700	COG2226	methyltransferase
GGC04_RS12705	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GGC04_RS12710	COG1388	LysM domain
GGC04_RS12710	COG0741	lytic transglycosylase activity
GGC04_RS12720	COG3021	interspecies interaction between organisms
GGC04_RS12725	COG0347	Belongs to the P(II) protein family
GGC04_RS12740	COG0825	malonyl-CoA metabolic process
GGC04_RS12745	COG0587	DNA-directed DNA polymerase activity
GGC04_RS12750	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GGC04_RS12765	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GGC04_RS12770	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GGC04_RS12775	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
GGC04_RS12780	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GGC04_RS12785	COG0750	zinc metalloprotease
GGC04_RS12795	COG0575	Belongs to the CDS family
GGC04_RS12800	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GGC04_RS12805	COG0233	cytoplasmic translational termination
GGC04_RS12810	COG0528	UMP kinase activity
GGC04_RS12815	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GGC04_RS12820	COG0052	Belongs to the universal ribosomal protein uS2 family
GGC04_RS12840	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GGC04_RS12845	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
GGC04_RS12850	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GGC04_RS12870	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GGC04_RS12870	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GGC04_RS12875	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GGC04_RS12880	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GGC04_RS12885	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GGC04_RS12895	COG1073	alpha beta
GGC04_RS12900	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
GGC04_RS12905	COG2252	PERMEase
GGC04_RS12910	COG2195	Cleaves the N-terminal amino acid of tripeptides
GGC04_RS12915	COG0189	ligase activity
GGC04_RS12915	COG4067	protein conserved in archaea
GGC04_RS12920	COG0189	ligase activity
GGC04_RS12930	COG0733	neurotransmitter:sodium symporter activity
GGC04_RS12945	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GGC04_RS12955	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GGC04_RS12970	COG1477	protein flavinylation
GGC04_RS12975	COG2871	sodium ion transport
GGC04_RS12980	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GGC04_RS12995	COG1805	sodium ion transport
GGC04_RS13000	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GGC04_RS13005	COG0271	Belongs to the BolA IbaG family
GGC04_RS13010	COG2813	Specifically methylates the guanine in position
GGC04_RS13020	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GGC04_RS13035	COG1595	DNA-templated transcription, initiation
GGC04_RS13050	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GGC04_RS13055	COG0693	protein deglycase activity
GGC04_RS13060	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GGC04_RS13065	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GGC04_RS13075	COG0560	Phosphoserine phosphatase
GGC04_RS13085	COG0813	purine-nucleoside phosphorylase activity
GGC04_RS13090	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
GGC04_RS13095	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
GGC04_RS13110	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GGC04_RS13115	COG0084	hydrolase, TatD family'
GGC04_RS13120	COG3022	response to hydroperoxide
GGC04_RS13125	COG1115	amino acid carrier protein
GGC04_RS13155	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GGC04_RS13185	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GGC04_RS13190	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
GGC04_RS13195	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
GGC04_RS13200	COG0583	DNA-binding transcription factor activity
GGC04_RS13205	COG0730	response to heat
GGC04_RS13210	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GGC04_RS13215	COG0505	Belongs to the CarA family
GGC04_RS13225	COG0494	nUDIX hydrolase
GGC04_RS13230	COG0653	protein targeting
GGC04_RS13235	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
GGC04_RS13240	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GGC04_RS13245	COG0849	cell division
GGC04_RS13250	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GGC04_RS13265	COG0772	Belongs to the SEDS family
GGC04_RS13270	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GGC04_RS13280	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GGC04_RS13290	COG0768	penicillin binding
GGC04_RS13295	COG3116	cell division
GGC04_RS13310	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GGC04_RS13315	COG3107	peptidoglycan biosynthetic process
GGC04_RS13325	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
GGC04_RS13335	COG2969	positive regulation of protein catabolic process
GGC04_RS13340	COG0625	glutathione transferase activity
GGC04_RS13345	COG2857	Cytochrome c1
GGC04_RS13350	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GGC04_RS13355	COG0723	plastoquinol--plastocyanin reductase activity
GGC04_RS13370	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
GGC04_RS13375	COG3105	Protein conserved in bacteria
GGC04_RS13380	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GGC04_RS13385	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GGC04_RS13400	COG3150	esterase
GGC04_RS13410	COG3151	Protein conserved in bacteria
GGC04_RS13415	COG0494	nUDIX hydrolase
GGC04_RS13420	COG1538	Outer membrane efflux protein
GGC04_RS13430	COG0784	Response regulator, receiver
GGC04_RS13430	COG2198	Histidine kinase
GGC04_RS13430	COG5002	protein histidine kinase activity
GGC04_RS13435	COG5001	Diguanylate cyclase
GGC04_RS13435	COG2203	Gaf domain
GGC04_RS13435	COG3706	GGDEF domain
GGC04_RS13435	COG4251	negative regulation of phosphorylation
GGC04_RS13440	COG1242	4 iron, 4 sulfur cluster binding
GGC04_RS13445	COG0067	glutamate synthase
GGC04_RS13445	COG0069	glutamate synthase activity
GGC04_RS13445	COG0070	glutamate synthase
GGC04_RS13455	COG0070	glutamate synthase
GGC04_RS13455	COG0069	glutamate synthase activity
GGC04_RS13455	COG0067	glutamate synthase
GGC04_RS13460	COG0493	'glutamate synthase
GGC04_RS13485	COG0195	Participates in both transcription termination and antitermination
GGC04_RS13490	COG0779	Required for maturation of 30S ribosomal subunits
GGC04_RS13505	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GGC04_RS13510	COG3153	acetyltransferase
GGC04_RS13515	COG3154	lipid carrier protein
GGC04_RS13525	COG0826	peptidase U32
GGC04_RS13530	COG0826	peptidase U32
GGC04_RS13535	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GGC04_RS13555	COG0513	Belongs to the DEAD box helicase family
GGC04_RS13585	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GGC04_RS13590	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GGC04_RS13595	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
GGC04_RS13600	COG1534	Rna-binding protein
GGC04_RS13605	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GGC04_RS13610	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GGC04_RS13615	COG2027	D-alanyl-D-alanine carboxypeptidase
GGC04_RS13625	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GGC04_RS13630	COG0739	heme binding
GGC04_RS13645	COG0316	Belongs to the HesB IscA family
GGC04_RS13655	COG0628	permease
GGC04_RS13660	COG2813	Specifically methylates the guanine in position
GGC04_RS13665	COG0784	Response regulator, receiver
GGC04_RS13665	COG2205	protein histidine kinase activity
GGC04_RS13670	COG0747	negative chemotaxis
GGC04_RS13685	COG0444	Belongs to the ABC transporter superfamily
GGC04_RS13690	COG4608	Belongs to the ABC transporter superfamily
GGC04_RS13700	COG2971	BadF BadG BcrA BcrD
GGC04_RS13715	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GGC04_RS13720	COG3842	ATPase activity
GGC04_RS13730	COG1840	ABC-type Fe3 transport system, periplasmic component
GGC04_RS13735	COG0004	ammonium transporteR
GGC04_RS13750	COG1049	propionate catabolic process, 2-methylcitrate cycle
GGC04_RS13755	COG1752	Esterase of the alpha-beta hydrolase superfamily
GGC04_RS13760	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GGC04_RS13765	COG1643	Atp-dependent helicase
GGC04_RS13775	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GGC04_RS13790	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GGC04_RS13795	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GGC04_RS13805	COG0842	Transport permease protein
GGC04_RS13810	COG1131	(ABC) transporter
GGC04_RS13815	COG0659	secondary active sulfate transmembrane transporter activity
GGC04_RS13820	COG0288	reversible hydration of carbon dioxide
GGC04_RS13835	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GGC04_RS13840	COG0508	dehydrogenase complex catalyzes the overall conversion of
GGC04_RS13845	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
GGC04_RS13850	COG2186	Transcriptional regulator
GGC04_RS13855	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GGC04_RS13860	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GGC04_RS13865	COG4974	Belongs to the 'phage' integrase family
GGC04_RS13875	COG3023	N-Acetylmuramoyl-L-alanine amidase
GGC04_RS13880	COG0157	Belongs to the NadC ModD family
GGC04_RS13885	COG4969	Belongs to the N-Me-Phe pilin family
GGC04_RS13890	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GGC04_RS13895	COG1459	type II secretion system
GGC04_RS13905	COG0237	dephospho-CoA kinase activity
GGC04_RS13910	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
GGC04_RS13915	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
GGC04_RS13925	COG0336	Belongs to the RNA methyltransferase TrmD family
GGC04_RS13935	COG0228	four-way junction DNA binding
GGC04_RS13940	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GGC04_RS13945	COG4137	Cytochrome C assembly protein
GGC04_RS13950	COG4536	flavin adenine dinucleotide binding
GGC04_RS13955	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GGC04_RS13970	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
GGC04_RS13975	COG0585	pseudouridine synthase activity
GGC04_RS13985	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GGC04_RS13990	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
GGC04_RS13995	COG1968	undecaprenyl-diphosphatase activity
GGC04_RS14000	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GGC04_RS14005	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GGC04_RS14010	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
GGC04_RS14015	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GGC04_RS14020	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GGC04_RS14025	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GGC04_RS14030	COG1610	YqeY-like protein
GGC04_RS14035	COG0358	DNA primase activity
GGC04_RS14050	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
GGC04_RS14055	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
GGC04_RS14060	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GGC04_RS14065	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
GGC04_RS14070	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GGC04_RS14080	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GGC04_RS14090	COG3610	response to peptide
GGC04_RS14095	COG2966	Psort location CytoplasmicMembrane, score
GGC04_RS14100	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GGC04_RS14110	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GGC04_RS14115	COG0142	geranyltranstransferase activity
GGC04_RS14125	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
GGC04_RS14130	COG2213	PTS system mannitol-specific
GGC04_RS14130	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GGC04_RS14140	COG3722	fumarate hydratase activity
GGC04_RS14145	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GGC04_RS14150	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GGC04_RS14155	COG1349	DNA-binding transcription factor activity
GGC04_RS14160	COG0469	pyruvate kinase activity
GGC04_RS14180	COG0583	DNA-binding transcription factor activity
GGC04_RS14195	COG0668	transmembrane transport
GGC04_RS14200	COG0191	fructose-bisphosphate aldolase activity
GGC04_RS14210	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GGC04_RS14215	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GGC04_RS14220	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GGC04_RS14230	COG3091	SprT-like family
GGC04_RS14235	COG2356	endonuclease I
GGC04_RS14240	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GGC04_RS14245	COG0189	ligase activity
GGC04_RS14250	COG1678	Uncharacterized ACR, COG1678
GGC04_RS14255	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GGC04_RS14270	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GGC04_RS14275	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GGC04_RS14280	COG0762	integral membrane protein
GGC04_RS14400	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GGC04_RS14405	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GGC04_RS14410	COG2066	Belongs to the glutaminase family
GGC04_RS14415	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GGC04_RS14425	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
GGC04_RS14480	COG0312	modulator of DNA gyrase
GGC04_RS14485	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GGC04_RS14490	COG3164	Protein of unknown function
GGC04_RS14500	COG0424	maF-like protein
GGC04_RS14505	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
GGC04_RS14510	COG1792	Involved in formation and maintenance of cell shape
GGC04_RS14515	COG1077	Cell shape determining protein MreB Mrl
GGC04_RS14550	COG2165	general secretion pathway protein
GGC04_RS14555	COG2165	general secretion pathway protein
GGC04_RS14565	COG1459	type II secretion system
GGC04_RS14570	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GGC04_RS14580	COG3409	Peptidoglycan-binding domain 1 protein
GGC04_RS14580	COG3267	Type II secretory pathway component ExeA
GGC04_RS14605	COG2200	EAL domain
GGC04_RS14605	COG2199	diguanylate cyclase activity
GGC04_RS14610	COG0629	single-stranded DNA binding
GGC04_RS14625	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GGC04_RS14635	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GGC04_RS14640	COG0527	aspartate kinase activity
GGC04_RS14645	COG0312	modulator of DNA gyrase
GGC04_RS14650	COG3028	Belongs to the UPF0307 family
GGC04_RS14655	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
GGC04_RS14660	COG1178	ABC-type Fe3 transport system permease component
GGC04_RS14665	COG4143	(ABC) transporter
GGC04_RS14670	COG0163	prenyltransferase activity
GGC04_RS14675	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GGC04_RS14685	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
GGC04_RS14690	COG2105	PFAM AIG2 family protein
GGC04_RS14695	COG2911	Protein conserved in bacteria
GGC04_RS14700	COG0729	surface antigen
GGC04_RS14705	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GGC04_RS14715	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
GGC04_RS14730	COG1136	(ABC) transporter
GGC04_RS14850	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GGC04_RS14855	COG0305	Participates in initiation and elongation during chromosome replication
GGC04_RS14875	COG0360	Binds together with S18 to 16S ribosomal RNA
GGC04_RS14885	COG2906	2 iron, 2 sulfur cluster binding
GGC04_RS14890	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GGC04_RS14895	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GGC04_RS14900	COG0049	tRNA binding
GGC04_RS14910	COG2168	tRNA wobble position uridine thiolation
GGC04_RS14915	COG2923	Belongs to the DsrF TusC family
GGC04_RS14920	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
GGC04_RS14925	COG2964	Protein conserved in bacteria
GGC04_RS14930	COG0545	Peptidyl-prolyl cis-trans isomerase
GGC04_RS14940	COG2900	Belongs to the SlyX family
GGC04_RS14945	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
GGC04_RS14950	COG0330	HflC and HflK could
GGC04_RS14955	COG0330	HflC and HflK could
GGC04_RS14960	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GGC04_RS14975	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GGC04_RS14985	COG0802	atpase or kinase
GGC04_RS14990	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GGC04_RS15045	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
GGC04_RS15050	COG1162	GTPase activity
GGC04_RS15055	COG0688	phosphatidylethanolamine metabolic process
GGC04_RS15060	COG0471	metal ion transport
GGC04_RS15060	COG0490	domain, Protein
GGC04_RS15065	COG0840	transmembrane signaling receptor activity
GGC04_RS15075	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GGC04_RS15080	COG4942	peptidase
GGC04_RS15100	COG2816	NAD+ diphosphatase activity
GGC04_RS15105	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
GGC04_RS15115	COG0085	RNA polymerase activity
GGC04_RS15125	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GGC04_RS15140	COG0250	Participates in transcription elongation, termination and antitermination
GGC04_RS15145	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GGC04_RS15150	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GGC04_RS15175	COG1072	(Pantothenic acid kinase))
GGC04_RS15190	COG0149	triose-phosphate isomerase activity
GGC04_RS15195	COG0534	Mate efflux family protein
GGC04_RS15200	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GGC04_RS15205	COG1575	Belongs to the MenA family. Type 1 subfamily
GGC04_RS15210	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GGC04_RS15215	COG1509	lysine 2,3-aminomutase activity
GGC04_RS15225	COG1285	pathogenesis
GGC04_RS15230	COG0205	6-phosphofructokinase activity
GGC04_RS15240	COG3678	ATP-independent chaperone mediated protein folding
GGC04_RS15245	COG0745	RESPONSE REGULATOR receiver
GGC04_RS15250	COG2205	protein histidine kinase activity
GGC04_RS15255	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GGC04_RS15260	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GGC04_RS15265	COG0180	Tryptophanyl-tRNA synthetase
GGC04_RS15270	COG0546	phosphoglycolate phosphatase activity
GGC04_RS15275	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GGC04_RS15280	COG0338	D12 class N6 adenine-specific DNA methyltransferase
GGC04_RS15290	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GGC04_RS15325	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
GGC04_RS15335	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GGC04_RS15335	COG0678	peroxiredoxin activity
GGC04_RS15345	COG0251	oxidation-reduction process
GGC04_RS15355	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GGC04_RS15355	COG0165	Argininosuccinate lyase
GGC04_RS15360	COG0137	argininosuccinate synthase activity
GGC04_RS15370	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GGC04_RS15375	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GGC04_RS15470	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GGC04_RS15480	COG4206	TonB-dependent receptor
GGC04_RS15500	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GGC04_RS15505	COG0534	Mate efflux family protein
GGC04_RS15515	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GGC04_RS15520	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GGC04_RS15525	COG2937	Belongs to the GPAT DAPAT family
GGC04_RS15530	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
GGC04_RS15535	COG3161	chorismate lyase activity
GGC04_RS15540	COG1580	Controls the rotational direction of flagella during chemotaxis
GGC04_RS15550	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GGC04_RS15555	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GGC04_RS15560	COG2177	Part of the ABC transporter FtsEX involved in
GGC04_RS15565	COG2884	Cell division ATP-binding protein ftsE
GGC04_RS15570	COG0552	protein localization to endoplasmic reticulum
GGC04_RS15575	COG0742	ribosomal rna small subunit methyltransferase
GGC04_RS15585	COG2095	MarC family integral membrane protein
GGC04_RS15635	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GGC04_RS15640	COG0640	Transcriptional regulator
GGC04_RS15645	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
GGC04_RS15650	COG1280	lysine exporter protein (LysE YggA)
GGC04_RS15660	COG0561	phosphatase activity
GGC04_RS15675	COG3148	PFAM DTW domain containing protein
GGC04_RS15680	COG2200	EAL domain
GGC04_RS15680	COG2199	diguanylate cyclase activity
GGC04_RS15680	COG3287	FIST C domain
GGC04_RS15685	COG1011	Hydrolase
GGC04_RS15690	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
GGC04_RS15700	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GGC04_RS15705	COG0019	diaminopimelate decarboxylase activity
GGC04_RS15715	COG1965	Belongs to the frataxin family
GGC04_RS15720	COG3072	Adenylate cyclase
GGC04_RS15725	COG0181	hydroxymethylbilane synthase activity
GGC04_RS15730	COG1587	Uroporphyrinogen-III synthase
GGC04_RS15735	COG2959	enzyme of heme biosynthesis
GGC04_RS15740	COG3071	HemY protein
GGC04_RS15805	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GGC04_RS15820	COG3118	belongs to the thioredoxin family
GGC04_RS15830	COG0248	Ppx GppA phosphatase
GGC04_RS15835	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
GGC04_RS15845	COG0514	ATP-dependent DNA helicase (RecQ)
GGC04_RS15850	COG2962	Rard protein
GGC04_RS15860	COG1280	lysine exporter protein (LysE YggA)
GGC04_RS15865	COG0405	Gamma-glutamyltransferase
GGC04_RS15885	COG0210	DNA helicase
GGC04_RS15895	COG3220	belongs to the UPF0276 family
GGC04_RS15915	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
GGC04_RS15920	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GGC04_RS15935	COG1773	rubredoxin
GGC04_RS15950	COG0367	asparagine synthase
GGC04_RS15955	COG0477	Major facilitator Superfamily
GGC04_RS15975	COG0745	RESPONSE REGULATOR receiver
GGC04_RS15990	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GGC04_RS15995	COG0601	transmembrane transport
GGC04_RS16000	COG0747	negative chemotaxis
GGC04_RS16035	COG1309	transcriptional regulator
GGC04_RS16040	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GGC04_RS16045	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GGC04_RS16050	COG2960	long-chain fatty acid transporting porin activity
GGC04_RS16055	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GGC04_RS16060	COG0583	DNA-binding transcription factor activity
GGC04_RS16065	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GGC04_RS16095	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GGC04_RS16095	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GGC04_RS16115	COG0084	hydrolase, TatD family'
GGC04_RS16120	COG0805	protein transport
GGC04_RS16125	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GGC04_RS16130	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GGC04_RS16145	COG2226	methyltransferase
GGC04_RS16150	COG1322	Protein conserved in bacteria
GGC04_RS16160	COG1639	'signal transduction protein
GGC04_RS16190	COG2081	HI0933 family
GGC04_RS16200	COG1528	Iron-storage protein
GGC04_RS16205	COG0589	response to stress
GGC04_RS16220	COG0742	ribosomal rna small subunit methyltransferase
GGC04_RS16225	COG5001	Diguanylate cyclase
GGC04_RS16225	COG5002	protein histidine kinase activity
GGC04_RS16230	COG1522	sequence-specific DNA binding
GGC04_RS16255	COG0006	proline dipeptidase activity
GGC04_RS16255	COG0006	proline dipeptidase activity
GGC04_RS16265	COG2022	thiamine diphosphate biosynthetic process
GGC04_RS16275	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GGC04_RS16280	COG0352	thiamine-phosphate diphosphorylase activity
GGC04_RS16295	COG2132	Multicopper oxidase
GGC04_RS16355	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GGC04_RS16360	COG1739	Uncharacterized protein family UPF0029
GGC04_RS16370	COG0183	Belongs to the thiolase family
GGC04_RS16375	COG3706	GGDEF domain
GGC04_RS16380	COG0583	DNA-binding transcription factor activity
GGC04_RS16385	COG2814	Major facilitator Superfamily
GGC04_RS16395	COG0765	amino acid transport
GGC04_RS16405	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GGC04_RS16410	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GGC04_RS16415	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GGC04_RS16420	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GGC04_RS16425	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GGC04_RS16445	COG3312	ion transport
GGC04_RS16450	COG1475	DNA binding
GGC04_RS16455	COG1192	Involved in chromosome partitioning
GGC04_RS16460	COG0357	Ribosomal RNA small subunit methyltransferase G
GGC04_RS16465	COG0445	tRNA wobble uridine modification
GGC04_RS16470	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GGC04_RS16475	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GGC04_RS16480	COG0706	membrane insertase activity
GGC04_RS16495	COG0230	Belongs to the bacterial ribosomal protein bL34 family
GGC04_RS16500	COG1126	abc transporter atp-binding protein
GGC04_RS16520	COG0366	Alpha amylase catalytic
GGC04_RS16530	COG2354	Protein conserved in bacteria
GGC04_RS16550	COG2199	diguanylate cyclase activity
GGC04_RS16555	COG1349	DNA-binding transcription factor activity
GGC04_RS16565	COG0633	Ferredoxin
GGC04_RS16565	COG3217	Mosc domain protein beta barrel domain protein
GGC04_RS16565	COG3217	Mosc domain protein beta barrel domain protein
GGC04_RS16565	COG0633	Ferredoxin
GGC04_RS16570	COG0418	dihydroorotase activity
GGC04_RS16590	COG2197	response regulator
GGC04_RS16595	COG3851	Histidine kinase
GGC04_RS16600	COG2271	Major facilitator Superfamily
GGC04_RS16610	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GGC04_RS16620	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GGC04_RS16625	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GGC04_RS16630	COG0363	glucosamine-6-phosphate deaminase activity
GGC04_RS16635	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GGC04_RS16655	COG3284	Transcriptional regulator
GGC04_RS16660	COG1012	belongs to the aldehyde dehydrogenase family
GGC04_RS16690	COG0579	oxidoreductase
GGC04_RS16695	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GGC04_RS16700	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GGC04_RS16710	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GGC04_RS16715	COG0840	transmembrane signaling receptor activity
GGC04_RS16740	COG2814	Major facilitator Superfamily
GGC04_RS16745	COG0583	DNA-binding transcription factor activity
GGC04_RS16770	COG0564	pseudouridine synthase activity
GGC04_RS16800	COG0251	oxidation-reduction process
GGC04_RS16840	COG0110	maltose O-acetyltransferase activity
GGC04_RS16850	COG1621	beta-fructofuranosidase activity
GGC04_RS16860	COG3842	ATPase activity
GGC04_RS16865	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GGC04_RS16870	COG1554	hydrolase, family 65, central catalytic
GGC04_RS16875	COG0395	ABC-type sugar transport system, permease component
GGC04_RS16880	COG1175	transmembrane transport
GGC04_RS16895	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GGC04_RS16905	COG0573	inorganic phosphate transmembrane transporter activity
GGC04_RS16945	COG1574	metal-dependent hydrolase with the TIM-barrel fold
GGC04_RS16955	COG0513	Belongs to the DEAD box helicase family
GGC04_RS16960	COG3097	Belongs to the UPF0267 family
GGC04_RS16975	COG3706	GGDEF domain
GGC04_RS16980	COG1309	transcriptional regulator
GGC04_RS16985	COG2130	NADP-dependent
GGC04_RS17000	COG2084	Dehydrogenase
GGC04_RS17020	COG0366	Alpha amylase catalytic
GGC04_RS17030	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GGC04_RS17035	COG0625	glutathione transferase activity
GGC04_RS17040	COG0346	lactoylglutathione lyase activity
GGC04_RS17045	COG1054	Belongs to the UPF0176 family
GGC04_RS17075	COG1131	(ABC) transporter
GGC04_RS17080	COG0842	Transport permease protein
GGC04_RS17115	COG5002	protein histidine kinase activity
GGC04_RS17120	COG0745	RESPONSE REGULATOR receiver
GGC04_RS17140	COG1309	transcriptional regulator
GGC04_RS17150	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GGC04_RS17175	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GGC04_RS17200	COG1805	sodium ion transport
GGC04_RS17205	COG1271	oxidase subunit
GGC04_RS17210	COG1294	oxidase, subunit
GGC04_RS17220	COG1357	PFAM Pentapeptide repeats (8 copies)
GGC04_RS17245	COG1522	sequence-specific DNA binding
GGC04_RS17255	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GGC04_RS17275	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GGC04_RS17280	COG2207	Transcriptional regulator
GGC04_RS17280	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GGC04_RS17315	COG0697	spore germination
GGC04_RS17335	COG0415	Belongs to the DNA photolyase family
GGC04_RS17345	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GGC04_RS17375	COG0840	transmembrane signaling receptor activity
GGC04_RS17405	COG0840	transmembrane signaling receptor activity
GGC04_RS17415	COG4580	involved in the transport of maltose and maltodextrins
GGC04_RS17430	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GGC04_RS17440	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GGC04_RS17445	COG0509	glycine decarboxylation via glycine cleavage system
GGC04_RS17465	COG0583	DNA-binding transcription factor activity
GGC04_RS17475	COG1132	(ABC) transporter
GGC04_RS17480	COG0589	response to stress
GGC04_RS17490	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GGC04_RS17490	COG2111	Na H antiporter
GGC04_RS17495	COG1006	Multisubunit Na H antiporter MnhC subunit
GGC04_RS17500	COG0651	ATP synthesis coupled electron transport
GGC04_RS17505	COG1863	multisubunit Na H antiporter MnhE subunit
GGC04_RS17510	COG2212	antiporter activity
GGC04_RS17515	COG1320	monovalent cation:proton antiporter activity
GGC04_RS17520	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GGC04_RS17520	COG4191	Histidine kinase
GGC04_RS17550	COG0488	(ABC) transporter
GGC04_RS17555	COG0673	inositol 2-dehydrogenase activity
GGC04_RS17565	COG5553	Cysteine dioxygenase type I
GGC04_RS17570	COG0300	oxidoreductase activity
GGC04_RS17595	COG3047	cAMP biosynthetic process
GGC04_RS17600	COG0739	heme binding
GGC04_RS17625	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GGC04_RS17630	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GGC04_RS17635	COG0446	pyridine nucleotide-disulphide oxidoreductase
GGC04_RS17640	COG3383	formate dehydrogenase (NAD+) activity
GGC04_RS17650	COG0004	ammonium transporteR
GGC04_RS17680	COG1234	tRNA 3'-trailer cleavage
GGC04_RS17685	COG0583	DNA-binding transcription factor activity
GGC04_RS17705	COG3304	Inner membrane component domain
GGC04_RS17710	COG2329	Antibiotic biosynthesis monooxygenase
GGC04_RS17720	COG3046	protein related to deoxyribodipyrimidine photolyase
GGC04_RS17725	COG0415	Belongs to the DNA photolyase family
GGC04_RS17755	COG3604	Transcriptional regulator
GGC04_RS17770	COG0583	DNA-binding transcription factor activity
GGC04_RS17780	COG1151	hydroxylamine reductase activity
GGC04_RS17785	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GGC04_RS17790	COG0583	DNA-binding transcription factor activity
GGC04_RS17800	COG3314	Sporulation integral membrane protein YlbJ
GGC04_RS17835	COG0745	RESPONSE REGULATOR receiver
GGC04_RS17850	COG1288	antiporter activity
GGC04_RS17855	COG3608	succinylglutamate desuccinylase aspartoacylase
GGC04_RS17885	COG1522	sequence-specific DNA binding
GGC04_RS17895	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
GGC04_RS17900	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
GGC04_RS17905	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GGC04_RS17935	COG0840	transmembrane signaling receptor activity
GGC04_RS17940	COG0454	-acetyltransferase
GGC04_RS17955	COG0363	glucosamine-6-phosphate deaminase activity
GGC04_RS17960	COG4720	Psort location CytoplasmicMembrane, score
GGC04_RS17965	COG1122	ATPase activity
GGC04_RS17985	COG1162	GTPase activity
GGC04_RS17990	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
GGC04_RS18005	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GGC04_RS18010	COG0581	inorganic phosphate transmembrane transporter activity
GGC04_RS18015	COG0573	inorganic phosphate transmembrane transporter activity
GGC04_RS18025	COG0840	transmembrane signaling receptor activity
GGC04_RS18030	COG4221	oxidoreductase activity
GGC04_RS18050	COG1477	protein flavinylation
GGC04_RS18105	COG2894	cell division
GGC04_RS18115	COG4964	Belongs to the GSP D family
GGC04_RS18150	COG2095	MarC family integral membrane protein
GGC04_RS18170	COG4176	ABC-type proline glycine betaine transport system permease component
GGC04_RS18175	COG3448	diguanylate cyclase activity
GGC04_RS18175	COG4175	Glycine betaine
GGC04_RS18185	COG0657	acetylesterase activity
GGC04_RS18235	COG0590	tRNA wobble adenosine to inosine editing
GGC04_RS18240	COG2076	Multidrug Resistance protein
GGC04_RS18245	COG2076	Multidrug Resistance protein
GGC04_RS18250	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
GGC04_RS18255	COG1960	acyl-CoA dehydrogenase activity
GGC04_RS18260	COG0662	Cupin 2, conserved barrel domain protein
GGC04_RS18270	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GGC04_RS18280	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GGC04_RS18305	COG4264	IucA IucC family
GGC04_RS18320	COG1120	ATPase activity
GGC04_RS18325	COG2814	Major facilitator Superfamily
GGC04_RS18335	COG4968	Prepilin-type N-terminal cleavage methylation domain
GGC04_RS18340	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GGC04_RS18340	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GGC04_RS18340	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GGC04_RS18350	COG0383	alpha-mannosidase activity
GGC04_RS18355	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GGC04_RS18355	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GGC04_RS18355	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
GGC04_RS18380	COG0583	DNA-binding transcription factor activity
GGC04_RS18390	COG1028	Short-chain dehydrogenase reductase Sdr
GGC04_RS18395	COG1414	Transcriptional regulator
GGC04_RS18420	COG0702	epimerase
GGC04_RS18465	COG1733	regulation of RNA biosynthetic process
GGC04_RS18485	COG1917	Cupin 2, conserved barrel domain protein
GGC04_RS18485	COG4977	sequence-specific DNA binding
GGC04_RS18490	COG4771	TonB-dependent receptor
GGC04_RS18495	COG2814	Major facilitator Superfamily
GGC04_RS18500	COG3433	isochorismatase activity
GGC04_RS18500	COG2226	methyltransferase
GGC04_RS18500	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GGC04_RS18520	COG1169	isochorismate synthase
GGC04_RS18525	COG1021	2,3-dihydroxybenzoate-AMP ligase
GGC04_RS18530	COG1132	(ABC) transporter
GGC04_RS18535	COG1132	(ABC) transporter
GGC04_RS18575	COG0561	phosphatase activity
GGC04_RS18625	COG0300	oxidoreductase activity
GGC04_RS18635	COG0583	DNA-binding transcription factor activity
GGC04_RS18645	COG2249	NAD(P)H dehydrogenase (quinone) activity
GGC04_RS18695	COG1619	proteins homologs of microcin C7 resistance protein MccF
GGC04_RS18710	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GGC04_RS18715	COG1640	4-alpha-glucanotransferase
GGC04_RS18720	COG0058	SHG alpha-glucan phosphorylase activity
GGC04_RS18725	COG2909	trisaccharide binding
GGC04_RS18735	COG0456	acetyltransferase
GGC04_RS18770	COG2207	Transcriptional regulator
GGC04_RS18775	COG1335	isochorismatase
GGC04_RS18780	COG1404	Belongs to the peptidase S8 family
GGC04_RS18785	COG0402	S-adenosylhomocysteine deaminase activity
GGC04_RS18815	COG3795	YCII-related domain
GGC04_RS18840	COG2186	Transcriptional regulator
GGC04_RS18850	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GGC04_RS18860	COG0402	S-adenosylhomocysteine deaminase activity
GGC04_RS18865	COG2226	methyltransferase
GGC04_RS18870	COG5002	protein histidine kinase activity
GGC04_RS18870	COG0784	Response regulator, receiver
GGC04_RS18870	COG2205	protein histidine kinase activity
GGC04_RS18880	COG1522	sequence-specific DNA binding
GGC04_RS18890	COG0840	transmembrane signaling receptor activity
GGC04_RS18905	COG4266	Belongs to the allantoicase family
GGC04_RS18925	COG2252	PERMEase
GGC04_RS18940	COG0596	Alpha beta hydrolase
GGC04_RS18945	COG3214	Protein conserved in bacteria
GGC04_RS18960	COG2205	protein histidine kinase activity
GGC04_RS18970	COG0583	DNA-binding transcription factor activity
GGC04_RS19000	COG3179	chitinase
GGC04_RS19015	COG0109	protoheme IX farnesyltransferase activity
GGC04_RS19020	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GGC04_RS19025	COG1845	cytochrome c oxidase, subunit III
GGC04_RS19030	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GGC04_RS19035	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GGC04_RS19045	COG2706	6-phosphogluconolactonase activity
GGC04_RS19055	COG0800	Aldolase
GGC04_RS19060	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GGC04_RS19065	COG4145	pantothenate transmembrane transporter activity
GGC04_RS19075	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
GGC04_RS19090	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GGC04_RS19095	COG0840	transmembrane signaling receptor activity
GGC04_RS19140	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
GGC04_RS19145	COG0804	urea catabolic process
GGC04_RS19150	COG0832	Belongs to the urease beta subunit family
GGC04_RS19155	COG0831	urea catabolic process
GGC04_RS19180	COG0559	Belongs to the binding-protein-dependent transport system permease family
GGC04_RS19195	COG2015	COG2015, Alkyl sulfatase and related hydrolases
GGC04_RS19210	COG2084	Dehydrogenase
GGC04_RS19215	COG3622	Belongs to the hyi family
GGC04_RS19220	COG3960	tartronate-semialdehyde synthase activity
GGC04_RS19225	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GGC04_RS19235	COG0583	DNA-binding transcription factor activity
GGC04_RS19240	COG1288	antiporter activity
GGC04_RS19270	COG1846	Transcriptional regulator
GGC04_RS19275	COG0697	spore germination
GGC04_RS19280	COG5001	Diguanylate cyclase
GGC04_RS19280	COG3300	MHYT domain
GGC04_RS19295	COG1051	belongs to the nudix hydrolase family
GGC04_RS19300	COG0583	DNA-binding transcription factor activity
GGC04_RS19320	COG1733	regulation of RNA biosynthetic process
GGC04_RS19325	COG1028	Short-chain dehydrogenase reductase Sdr
GGC04_RS19335	COG1028	Short-chain dehydrogenase reductase Sdr
GGC04_RS19370	COG0444	Belongs to the ABC transporter superfamily
GGC04_RS19375	COG4608	Belongs to the ABC transporter superfamily
GGC04_RS19405	COG1444	tRNA N-acetyltransferase activity
GGC04_RS19410	COG0840	transmembrane signaling receptor activity
GGC04_RS19435	COG0835	chemotaxis
GGC04_RS19440	COG0840	transmembrane signaling receptor activity
GGC04_RS19445	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GGC04_RS19490	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GGC04_RS19515	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GGC04_RS19550	COG0583	DNA-binding transcription factor activity
GGC04_RS19555	COG1175	transmembrane transport
GGC04_RS19575	COG0546	phosphoglycolate phosphatase activity
GGC04_RS19580	COG3842	ATPase activity
GGC04_RS19585	COG0589	response to stress
GGC04_RS19590	COG2723	6-phospho-beta-galactosidase activity
GGC04_RS19595	COG0768	penicillin binding
GGC04_RS19600	COG0840	transmembrane signaling receptor activity
GGC04_RS19625	COG0583	DNA-binding transcription factor activity
GGC04_RS19640	COG3321	synthase
GGC04_RS19640	COG1028	Short-chain dehydrogenase reductase Sdr
GGC04_RS19640	COG0604	alcohol dehydrogenase
GGC04_RS19645	COG0656	L-ascorbic acid biosynthetic process
GGC04_RS19650	COG0351	phosphomethylpyrimidine kinase
GGC04_RS19655	COG1116	anion transmembrane transporter activity
GGC04_RS19660	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GGC04_RS19665	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GGC04_RS19670	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GGC04_RS19690	COG3708	Transcriptional regulator
GGC04_RS19690	COG2207	Transcriptional regulator
GGC04_RS19700	COG0671	phosphoesterase, PA-phosphatase related
GGC04_RS19710	COG0438	transferase activity, transferring glycosyl groups
GGC04_RS19720	COG1940	carbohydrate kinase activity
GGC04_RS19735	COG1175	transmembrane transport
GGC04_RS19745	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GGC04_RS19765	COG0583	DNA-binding transcription factor activity
GGC04_RS19785	COG1063	alcohol dehydrogenase
GGC04_RS19795	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GGC04_RS19795	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GGC04_RS19805	COG0251	oxidation-reduction process
GGC04_RS19810	COG0697	spore germination
GGC04_RS19825	COG1595	DNA-templated transcription, initiation
GGC04_RS19835	COG3314	Sporulation integral membrane protein YlbJ
GGC04_RS19865	COG0471	metal ion transport
GGC04_RS19870	COG2205	protein histidine kinase activity
GGC04_RS19875	COG0745	RESPONSE REGULATOR receiver
GGC04_RS19900	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GGC04_RS19910	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GGC04_RS19915	COG0745	RESPONSE REGULATOR receiver
GGC04_RS19920	COG2205	protein histidine kinase activity
GGC04_RS19920	COG3850	Histidine kinase
GGC04_RS19920	COG3437	response regulator, receiver
GGC04_RS19920	COG4999	Histidine kinase
GGC04_RS19935	COG5002	protein histidine kinase activity
GGC04_RS19940	COG0745	RESPONSE REGULATOR receiver
GGC04_RS19950	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GGC04_RS19965	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GGC04_RS19970	COG3366	ferrous iron transmembrane transporter activity
GGC04_RS19975	COG0700	Nucleoside recognition
GGC04_RS19985	COG2207	Transcriptional regulator
GGC04_RS20005	COG1301	dicarboxylic acid transport
GGC04_RS20155	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
GGC04_RS20180	COG0346	lactoylglutathione lyase activity
GGC04_RS20190	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GGC04_RS20200	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GGC04_RS20235	COG2814	Major facilitator Superfamily
GGC04_RS20240	COG0583	DNA-binding transcription factor activity
GGC04_RS20245	COG0393	Putative heavy-metal-binding
GGC04_RS20250	COG1671	Belongs to the UPF0178 family
GGC04_RS20265	COG1999	signal sequence binding
GGC04_RS20275	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GGC04_RS20280	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GGC04_RS20285	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
GGC04_RS20290	COG3033	Beta-eliminating lyase
GGC04_RS20320	COG0259	pyridoxamine-phosphate oxidase activity
GGC04_RS20330	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GGC04_RS20375	COG1132	(ABC) transporter
GGC04_RS20385	COG0583	DNA-binding transcription factor activity
GGC04_RS20400	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GGC04_RS20410	COG0786	glutamate:sodium symporter activity
GGC04_RS20415	COG1566	PFAM secretion protein HlyD family protein
GGC04_RS20430	COG3706	GGDEF domain
GGC04_RS20445	COG0813	purine-nucleoside phosphorylase activity
GGC04_RS20450	COG3272	Protein of unknown function (DUF1722)
GGC04_RS20455	COG0789	Transcriptional regulator
GGC04_RS20460	COG0415	Belongs to the DNA photolyase family
GGC04_RS20465	COG1388	LysM domain
GGC04_RS20465	COG1376	ErfK ybiS ycfS ynhG family protein
GGC04_RS20475	COG0513	Belongs to the DEAD box helicase family
GGC04_RS20480	COG3291	Pkd domain containing protein
GGC04_RS20490	COG3568	Endonuclease Exonuclease Phosphatase
GGC04_RS20525	COG0006	proline dipeptidase activity
GGC04_RS20540	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GGC04_RS20545	COG0601	transmembrane transport
GGC04_RS20560	COG2186	Transcriptional regulator
GGC04_RS20570	COG3938	Belongs to the proline racemase family
GGC04_RS20585	COG2423	ornithine cyclodeaminase activity
GGC04_RS20590	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GGC04_RS20595	COG3842	ATPase activity
GGC04_RS20600	COG1176	ABC-type spermidine putrescine transport system, permease component I
GGC04_RS20605	COG1177	transmembrane transport
GGC04_RS20615	COG1280	lysine exporter protein (LysE YggA)
GGC04_RS20625	COG1846	Transcriptional regulator
GGC04_RS20665	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
GGC04_RS20670	COG2988	succinylglutamate desuccinylase activity
GGC04_RS20675	COG0523	cobalamin synthesis protein
GGC04_RS20680	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GGC04_RS20680	COG4451	ribulose bisphosphate carboxylase, small
GGC04_RS20685	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GGC04_RS20740	COG0583	DNA-binding transcription factor activity
GGC04_RS20745	COG1280	lysine exporter protein (LysE YggA)
GGC04_RS20785	COG1253	flavin adenine dinucleotide binding
GGC04_RS20820	COG0583	DNA-binding transcription factor activity
GGC04_RS20825	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GGC04_RS20830	COG1686	Belongs to the peptidase S11 family
GGC04_RS20835	COG2814	Major facilitator Superfamily
GGC04_RS20845	COG1741	Belongs to the pirin family
GGC04_RS20860	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GGC04_RS20885	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GGC04_RS20895	COG3314	Sporulation integral membrane protein YlbJ
GGC04_RS20905	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
GGC04_RS20925	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GGC04_RS20930	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GGC04_RS20935	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GGC04_RS20940	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
GGC04_RS20965	COG1612	heme a metabolic process
GGC04_RS20970	COG0109	protoheme IX farnesyltransferase activity
GGC04_RS20975	COG0765	amino acid transport
GGC04_RS20980	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GGC04_RS20985	COG0765	amino acid transport
GGC04_RS20990	COG1126	abc transporter atp-binding protein
GGC04_RS20995	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GGC04_RS21005	COG0366	Alpha amylase catalytic
GGC04_RS21015	COG4989	oxidoreductase activity
GGC04_RS21020	COG2203	Gaf domain
GGC04_RS21020	COG5001	Diguanylate cyclase
GGC04_RS21020	COG4251	negative regulation of phosphorylation
GGC04_RS21020	COG3706	GGDEF domain
GGC04_RS21030	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GGC04_RS21035	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GGC04_RS21040	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GGC04_RS21045	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
GGC04_RS21050	COG0438	transferase activity, transferring glycosyl groups
GGC04_RS21065	COG1045	serine acetyltransferase
GGC04_RS21075	COG0438	transferase activity, transferring glycosyl groups
GGC04_RS21075	COG0297	glycogen (starch) synthase activity
GGC04_RS21085	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
GGC04_RS21135	COG5001	Diguanylate cyclase
GGC04_RS21140	COG0583	DNA-binding transcription factor activity
GGC04_RS21145	COG2814	Major facilitator Superfamily
GGC04_RS21160	COG0697	spore germination
GGC04_RS21170	COG0534	Mate efflux family protein
GGC04_RS21180	COG2249	NAD(P)H dehydrogenase (quinone) activity
GGC04_RS21185	COG0546	phosphoglycolate phosphatase activity
GGC04_RS21195	COG3604	Transcriptional regulator
GGC04_RS21200	COG1017	nitric oxide dioxygenase activity
GGC04_RS21200	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GGC04_RS21215	COG1278	Cold shock
GGC04_RS21220	COG3036	rescue of stalled ribosome
GGC04_RS21235	COG1686	Belongs to the peptidase S11 family
GGC04_RS21250	COG3530	Putative quorum-sensing-regulated virulence factor
GGC04_RS21270	COG1012	belongs to the aldehyde dehydrogenase family
GGC04_RS21285	COG1136	(ABC) transporter
GGC04_RS21305	COG3275	phosphorelay sensor kinase activity
GGC04_RS21310	COG3279	Response regulator of the LytR AlgR family
GGC04_RS21340	COG0366	Alpha amylase catalytic
GGC04_RS21360	COG0747	negative chemotaxis
GGC04_RS21365	COG4608	Belongs to the ABC transporter superfamily
GGC04_RS21370	COG0444	Belongs to the ABC transporter superfamily
GGC04_RS21375	COG0534	Mate efflux family protein
GGC04_RS21390	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GGC04_RS21405	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GGC04_RS21420	COG2130	NADP-dependent
GGC04_RS21440	COG0642	Histidine kinase
GGC04_RS21450	COG3706	GGDEF domain
GGC04_RS21460	COG5001	Diguanylate cyclase
GGC04_RS21465	COG1396	sequence-specific DNA binding
GGC04_RS21470	COG4948	Mandelate Racemase Muconate Lactonizing
GGC04_RS21480	COG0583	DNA-binding transcription factor activity
GGC04_RS21485	COG0443	Heat shock 70 kDa protein
GGC04_RS21515	COG1280	lysine exporter protein (LysE YggA)
GGC04_RS21530	COG4232	protein-disulfide reductase activity
GGC04_RS21535	COG3118	belongs to the thioredoxin family
GGC04_RS21575	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GGC04_RS21595	COG0668	transmembrane transport
GGC04_RS21605	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
GGC04_RS21610	COG3123	guanosine phosphorylase activity
GGC04_RS21625	COG0583	DNA-binding transcription factor activity
GGC04_RS21650	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
GGC04_RS21660	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GGC04_RS21660	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
GGC04_RS21665	COG3265	gluconokinase activity
GGC04_RS21670	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GGC04_RS21675	COG1609	Transcriptional regulator
GGC04_RS21695	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GGC04_RS21700	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GGC04_RS21705	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
GGC04_RS21710	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
GGC04_RS21740	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
GGC04_RS21745	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GGC04_RS21765	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GGC04_RS21790	COG0004	ammonium transporteR
GGC04_RS21805	COG3469	chitinase activity
GGC04_RS21815	COG1869	D-ribose catabolic process
GGC04_RS21820	COG1129	ABC transporter
GGC04_RS21825	COG1172	Belongs to the binding-protein-dependent transport system permease family
GGC04_RS21830	COG1879	ABC-type sugar transport system periplasmic component
GGC04_RS21835	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GGC04_RS21840	COG1609	Transcriptional regulator
GGC04_RS21845	COG0784	Response regulator, receiver
GGC04_RS21845	COG3437	response regulator, receiver
GGC04_RS21850	COG4191	Histidine kinase
GGC04_RS21850	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GGC04_RS21860	COG0513	Belongs to the DEAD box helicase family
GGC04_RS21870	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
GGC04_RS21880	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GGC04_RS21895	COG0739	heme binding
GGC04_RS21905	COG2814	Major facilitator Superfamily
GGC04_RS21910	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
GGC04_RS21915	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GGC04_RS21925	COG0848	biopolymer transport protein
GGC04_RS21930	COG0811	peptide transport
GGC04_RS21935	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
GGC04_RS21945	COG3721	Heme iron utilization protein
GGC04_RS21950	COG0748	coenzyme F420 binding
GGC04_RS21955	COG2096	Adenosyltransferase
GGC04_RS21960	COG3842	ATPase activity
GGC04_RS21970	COG1175	transmembrane transport
GGC04_RS21975	COG3833	ABC-type maltose transport systems, permease component
GGC04_RS21990	COG4533	DNA binding
GGC04_RS22030	COG2205	protein histidine kinase activity
GGC04_RS22030	COG0784	Response regulator, receiver
GGC04_RS22030	COG5002	protein histidine kinase activity
GGC04_RS22040	COG0861	Integral membrane protein TerC family
GGC04_RS22045	COG0402	S-adenosylhomocysteine deaminase activity
GGC04_RS22050	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GGC04_RS22055	COG1566	PFAM secretion protein HlyD family protein
GGC04_RS22080	COG0745	RESPONSE REGULATOR receiver
GGC04_RS22105	COG0531	amino acid
GGC04_RS22125	COG0673	inositol 2-dehydrogenase activity
GGC04_RS22130	COG1765	OsmC-like protein
GGC04_RS22135	COG0110	maltose O-acetyltransferase activity
GGC04_RS22155	COG2304	oxidoreductase activity
GGC04_RS22160	COG2304	oxidoreductase activity
GGC04_RS22175	COG0714	Associated with various cellular activities
GGC04_RS22190	COG0583	DNA-binding transcription factor activity
GGC04_RS22195	COG0667	Aldo Keto reductase
GGC04_RS22210	COG2205	protein histidine kinase activity
GGC04_RS22215	COG0745	RESPONSE REGULATOR receiver
GGC04_RS22225	COG0745	RESPONSE REGULATOR receiver
GGC04_RS22230	COG2205	protein histidine kinase activity
GGC04_RS22235	COG4452	Inner membrane protein CreD
GGC04_RS22245	COG0346	lactoylglutathione lyase activity
GGC04_RS22265	COG2202	Pas domain
GGC04_RS22265	COG2199	diguanylate cyclase activity
GGC04_RS22265	COG2200	EAL domain
GGC04_RS22270	COG0156	8-amino-7-oxononanoate synthase activity
GGC04_RS22275	COG1063	alcohol dehydrogenase
GGC04_RS22305	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GGC04_RS22315	COG2195	Cleaves the N-terminal amino acid of tripeptides
GGC04_RS22335	COG0798	PFAM Bile acid sodium symporter
GGC04_RS22345	COG0612	Peptidase, M16
GGC04_RS22350	COG2205	protein histidine kinase activity
GGC04_RS22350	COG0784	Response regulator, receiver
GGC04_RS22355	COG2205	protein histidine kinase activity
GGC04_RS22355	COG0784	Response regulator, receiver
GGC04_RS22375	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GGC04_RS22380	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GGC04_RS22385	COG3186	Phenylalanine-4-hydroxylase
GGC04_RS22435	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GGC04_RS22440	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GGC04_RS22485	COG1454	alcohol dehydrogenase
GGC04_RS22490	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
GGC04_RS22500	COG1011	Hydrolase
GGC04_RS22510	COG2378	regulation of single-species biofilm formation
GGC04_RS22530	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GGC04_RS22535	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GGC04_RS22540	COG1840	ABC-type Fe3 transport system, periplasmic component
GGC04_RS22550	COG3842	ATPase activity
GGC04_RS22575	COG3104	oligopeptide transport
GGC04_RS22580	COG2866	Carboxypeptidase
GGC04_RS22585	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GGC04_RS22590	COG0583	DNA-binding transcription factor activity
GGC04_RS22595	COG1760	l-serine dehydratase
GGC04_RS22620	COG3706	GGDEF domain
GGC04_RS22625	COG0784	Response regulator, receiver
GGC04_RS22625	COG0835	chemotaxis
GGC04_RS22630	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GGC04_RS22645	COG1028	Short-chain dehydrogenase reductase Sdr
GGC04_RS22655	COG0494	nUDIX hydrolase
GGC04_RS22660	COG0714	Associated with various cellular activities
GGC04_RS22665	COG2425	protein containing a von Willebrand factor type A (vWA) domain
GGC04_RS22670	COG2814	Major facilitator Superfamily
GGC04_RS22695	COG3706	GGDEF domain
GGC04_RS22700	COG1846	Transcriptional regulator
GGC04_RS22705	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GGC04_RS22710	COG2176	DNA-directed DNA polymerase activity
GGC04_RS22720	COG0789	Transcriptional regulator
GGC04_RS22730	COG5001	Diguanylate cyclase
GGC04_RS22730	COG3300	MHYT domain
GGC04_RS22735	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GGC04_RS22740	COG0583	DNA-binding transcription factor activity
GGC04_RS22765	COG1858	cytochrome C peroxidase
GGC04_RS22790	COG1716	ATPase activity
GGC04_RS22790	COG5001	Diguanylate cyclase
GGC04_RS22810	COG2910	NAD(P)H-binding
GGC04_RS22815	COG0583	DNA-binding transcription factor activity
GGC04_RS22820	COG1115	amino acid carrier protein
GGC04_RS22835	COG1741	Belongs to the pirin family
GGC04_RS22840	COG2259	Doxx family
GGC04_RS22875	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GGC04_RS22880	COG1960	acyl-CoA dehydrogenase activity
GGC04_RS22890	COG0183	Belongs to the thiolase family
GGC04_RS22900	COG1960	acyl-CoA dehydrogenase activity
GGC04_RS22905	COG1024	Enoyl-CoA hydratase
GGC04_RS22910	COG1024	Enoyl-CoA hydratase
GGC04_RS22920	COG1028	Short-chain dehydrogenase reductase Sdr
GGC04_RS22925	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
GGC04_RS22945	COG3706	GGDEF domain
GGC04_RS22970	COG2199	diguanylate cyclase activity
GGC04_RS22970	COG2203	Gaf domain
GGC04_RS22980	COG2315	Protein conserved in bacteria
GGC04_RS23025	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GGC04_RS23025	COG1648	precorrin-2 dehydrogenase activity
GGC04_RS23030	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GGC04_RS23040	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GGC04_RS23040	COG1116	anion transmembrane transporter activity
GGC04_RS23045	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GGC04_RS23050	COG1116	anion transmembrane transporter activity
GGC04_RS23055	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GGC04_RS23055	COG2146	nitrite reductase [NAD(P)H] activity
GGC04_RS23060	COG2146	nitrite reductase [NAD(P)H] activity
GGC04_RS23085	COG3118	belongs to the thioredoxin family
GGC04_RS23090	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GGC04_RS23100	COG0419	ATPase involved in DNA repair
GGC04_RS23105	COG2205	protein histidine kinase activity
GGC04_RS23105	COG0784	Response regulator, receiver
GGC04_RS23110	COG0156	8-amino-7-oxononanoate synthase activity
GGC04_RS23120	COG0038	chloride channel
GGC04_RS23125	COG0523	cobalamin synthesis protein
GGC04_RS23130	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GGC04_RS23140	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GGC04_RS23175	COG1522	sequence-specific DNA binding
GGC04_RS23185	COG1473	amidohydrolase
GGC04_RS23190	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GGC04_RS23195	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
GGC04_RS23200	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GGC04_RS23205	COG0006	proline dipeptidase activity
GGC04_RS23215	COG1522	sequence-specific DNA binding
GGC04_RS23220	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GGC04_RS23225	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GGC04_RS23250	COG2897	thiosulfate sulfurtransferase activity
GGC04_RS23260	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GGC04_RS23275	COG0513	Belongs to the DEAD box helicase family
GGC04_RS23285	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GGC04_RS23285	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GGC04_RS23290	COG0814	amino acid
GGC04_RS23300	COG0513	Belongs to the DEAD box helicase family
GGC04_RS23330	COG1214	PFAM Peptidase M22, glycoprotease
GGC04_RS23330	COG0456	acetyltransferase
GGC04_RS23345	COG0346	lactoylglutathione lyase activity
GGC04_RS23355	COG3048	D-serine ammonia-lyase activity
GGC04_RS23360	COG0583	DNA-binding transcription factor activity
GGC04_RS23370	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GGC04_RS23375	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GGC04_RS23390	COG0546	phosphoglycolate phosphatase activity
GGC04_RS23400	COG0800	Aldolase
GGC04_RS23405	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GGC04_RS23410	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GGC04_RS23410	COG1263	PTS System
GGC04_RS23420	COG2188	Transcriptional regulator
GGC04_RS23425	COG1803	Methylglyoxal synthase
GGC04_RS23430	COG1879	ABC-type sugar transport system periplasmic component
GGC04_RS23435	COG2198	Histidine kinase
GGC04_RS23435	COG0784	Response regulator, receiver
GGC04_RS23435	COG2205	protein histidine kinase activity
GGC04_RS23450	COG1979	alcohol dehydrogenase
GGC04_RS23455	COG2207	Transcriptional regulator
GGC04_RS23460	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GGC04_RS23465	COG3706	GGDEF domain
GGC04_RS23470	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GGC04_RS23470	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
GGC04_RS23470	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GGC04_RS23475	COG1105	Belongs to the carbohydrate kinase PfkB family
GGC04_RS23480	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GGC04_RS23480	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GGC04_RS23485	COG1609	Transcriptional regulator
GGC04_RS23505	COG0725	ABC transporter, periplasmic molybdate-binding protein
GGC04_RS23510	COG4149	molybdate abc transporter
GGC04_RS23515	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
GGC04_RS23525	COG4251	negative regulation of phosphorylation
GGC04_RS23525	COG2203	Gaf domain
GGC04_RS23525	COG5001	Diguanylate cyclase
GGC04_RS23525	COG3706	GGDEF domain
GGC04_RS23530	COG3706	GGDEF domain
GGC04_RS23545	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
GGC04_RS23550	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
GGC04_RS23560	COG0745	RESPONSE REGULATOR receiver
GGC04_RS23575	COG3140	Belongs to the UPF0181 family
GGC04_RS23590	COG0023	Translation Initiation Factor
GGC04_RS23605	COG1181	Belongs to the D-alanine--D-alanine ligase family
GGC04_RS23610	COG3266	domain, Protein
GGC04_RS23615	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GGC04_RS23615	COG0045	succinate-CoA ligase (ADP-forming) activity
GGC04_RS23615	COG1042	CoA-binding domain protein
GGC04_RS23620	COG0583	DNA-binding transcription factor activity
GGC04_RS23625	COG1629	transport
GGC04_RS23625	COG4771	TonB-dependent receptor
GGC04_RS23645	COG2050	protein possibly involved in aromatic compounds catabolism
GGC04_RS23665	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GGC04_RS23670	COG3070	regulator of competence-specific genes
GGC04_RS23675	COG0840	transmembrane signaling receptor activity
GGC04_RS23680	COG2205	protein histidine kinase activity
GGC04_RS23680	COG0784	Response regulator, receiver
GGC04_RS23685	COG0745	RESPONSE REGULATOR receiver
GGC04_RS23700	COG1605	Chorismate mutase
GGC04_RS23730	COG0737	Belongs to the 5'-nucleotidase family
GGC04_RS23735	COG3593	DNA synthesis involved in DNA repair
GGC04_RS23745	COG0583	DNA-binding transcription factor activity
GGC04_RS23750	COG2116	formate transmembrane transporter activity
GGC04_RS23755	COG2353	YceI-like domain
GGC04_RS23760	COG3038	cytochrome b561
GGC04_RS23780	COG3069	C4-dicarboxylate transmembrane transporter activity
GGC04_RS23785	COG2197	response regulator
GGC04_RS23790	COG3850	Histidine kinase
GGC04_RS23795	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GGC04_RS23805	COG0243	molybdopterin cofactor binding
GGC04_RS23825	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GGC04_RS23830	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
GGC04_RS23840	COG1984	allophanate hydrolase subunit 2
GGC04_RS23845	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
GGC04_RS23850	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
GGC04_RS23855	COG4181	ATPase activity
GGC04_RS23865	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GGC04_RS23870	COG3300	MHYT domain
GGC04_RS23870	COG5001	Diguanylate cyclase
GGC04_RS23880	COG0484	heat shock protein binding
GGC04_RS23900	COG0210	DNA helicase
GGC04_RS23905	COG1289	transmembrane transporter activity
GGC04_RS23930	COG0784	Response regulator, receiver
GGC04_RS23930	COG5002	protein histidine kinase activity
GGC04_RS23945	COG2827	Endonuclease containing a URI domain
GGC04_RS23950	COG3132	Protein of unknown function, DUF480
GGC04_RS23960	COG2926	Belongs to the UPF0265 family
GGC04_RS23970	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GGC04_RS23975	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GGC04_RS23980	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GGC04_RS23985	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
GGC04_RS23990	COG0247	lactate metabolic process
GGC04_RS24010	COG0545	Peptidyl-prolyl cis-trans isomerase
GGC04_RS24020	COG4067	protein conserved in archaea
GGC04_RS24020	COG0189	ligase activity
GGC04_RS24030	COG0602	queuosine metabolic process
GGC04_RS24035	COG1328	CTP reductase activity
GGC04_RS24085	COG3240	lipase activity
GGC04_RS24090	COG2814	Major facilitator Superfamily
GGC04_RS24095	COG1794	racemase activity, acting on amino acids and derivatives
GGC04_RS24110	COG0183	Belongs to the thiolase family
GGC04_RS24125	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GGC04_RS24130	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GGC04_RS24135	COG1309	transcriptional regulator
GGC04_RS24140	COG1609	Transcriptional regulator
GGC04_RS24155	COG2211	Major facilitator Superfamily
GGC04_RS24160	COG3250	beta-galactosidase activity
GGC04_RS24200	COG1522	sequence-specific DNA binding
GGC04_RS24235	COG2815	serine threonine protein kinase
GGC04_RS24235	COG0515	serine threonine protein kinase
GGC04_RS24260	COG3501	Rhs element vgr protein
GGC04_RS24300	COG0739	heme binding
GGC04_RS24310	COG2203	Gaf domain
GGC04_RS24310	COG2199	diguanylate cyclase activity
GGC04_RS24315	COG0840	transmembrane signaling receptor activity
GGC04_RS24325	COG2271	Major facilitator Superfamily
GGC04_RS24345	COG4206	TonB-dependent receptor
GGC04_RS24355	COG0004	ammonium transporteR
GGC04_RS24370	COG2759	Belongs to the formate--tetrahydrofolate ligase family
GGC04_RS24375	COG4604	ABC transporter, ATP-binding protein
GGC04_RS24380	COG4605	iron ion homeostasis
GGC04_RS24385	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GGC04_RS24435	COG4172	Belongs to the ABC transporter superfamily
GGC04_RS24440	COG4239	(ABC) transporter, permease
GGC04_RS24445	COG4174	ABC transporter (Permease)
GGC04_RS24450	COG4166	transmembrane transport
GGC04_RS24465	COG0840	transmembrane signaling receptor activity
GGC04_RS24470	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GGC04_RS24475	COG1067	ATP-dependent peptidase activity
GGC04_RS24485	COG4172	Belongs to the ABC transporter superfamily
GGC04_RS24490	COG0583	DNA-binding transcription factor activity
GGC04_RS24495	COG1620	l-lactate permease
GGC04_RS24500	COG1304	FMN binding
GGC04_RS24520	COG3448	diguanylate cyclase activity
GGC04_RS24520	COG4175	Glycine betaine
GGC04_RS24540	COG1012	belongs to the aldehyde dehydrogenase family
GGC04_RS24545	COG1309	transcriptional regulator
GGC04_RS24560	COG1404	Belongs to the peptidase S8 family
GGC04_RS24565	COG1346	cytolysis
GGC04_RS24575	COG0516	GMP reductase activity
GGC04_RS24580	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GGC04_RS24580	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GGC04_RS24595	COG3437	response regulator, receiver
GGC04_RS24600	COG3437	response regulator, receiver
GGC04_RS24600	COG4999	Histidine kinase
GGC04_RS24600	COG3850	Histidine kinase
GGC04_RS24600	COG2205	protein histidine kinase activity
GGC04_RS24610	COG2172	sigma factor antagonist activity
GGC04_RS24620	COG1366	Belongs to the anti-sigma-factor antagonist family
GGC04_RS24625	COG0840	transmembrane signaling receptor activity
GGC04_RS24720	COG1309	transcriptional regulator
GGC04_RS24725	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GGC04_RS24730	COG1360	Flagellar Motor Protein
GGC04_RS24750	COG0702	epimerase
GGC04_RS24775	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
GGC04_RS24785	COG1879	ABC-type sugar transport system periplasmic component
GGC04_RS24800	COG5001	Diguanylate cyclase
GGC04_RS24800	COG2203	Gaf domain
GGC04_RS24800	COG4251	negative regulation of phosphorylation
GGC04_RS24800	COG3706	GGDEF domain
GGC04_RS24815	COG0431	NADPH-dependent FMN reductase
GGC04_RS24820	COG0583	DNA-binding transcription factor activity
GGC04_RS24825	COG0583	DNA-binding transcription factor activity
GGC04_RS24845	COG0840	transmembrane signaling receptor activity
GGC04_RS24860	COG2203	Gaf domain
GGC04_RS24860	COG3706	GGDEF domain
GGC04_RS24860	COG4251	negative regulation of phosphorylation
GGC04_RS24860	COG5001	Diguanylate cyclase
GGC04_RS24870	COG0745	RESPONSE REGULATOR receiver
GGC04_RS24880	COG1028	Short-chain dehydrogenase reductase Sdr
GGC04_RS24885	COG0583	DNA-binding transcription factor activity
GGC04_RS24895	COG3527	Alpha-acetolactate decarboxylase
GGC04_RS24905	COG0745	RESPONSE REGULATOR receiver
GGC04_RS24910	COG2205	protein histidine kinase activity
GGC04_RS24940	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
GGC04_RS25010	COG0671	phosphoesterase, PA-phosphatase related
GGC04_RS25025	COG0113	porphobilinogen synthase activity
GGC04_RS25030	COG0183	Belongs to the thiolase family
GGC04_RS25040	COG3246	L-lysine catabolic process to acetate
GGC04_RS25055	COG0604	alcohol dehydrogenase
GGC04_RS25070	COG0702	epimerase
GGC04_RS25090	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
GGC04_RS25100	COG0583	DNA-binding transcription factor activity
GGC04_RS25105	COG1028	Short-chain dehydrogenase reductase Sdr
GGC04_RS25205	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GGC04_RS25215	COG2084	Dehydrogenase
GGC04_RS25290	COG4774	siderophore transport
GGC04_RS25310	COG0494	nUDIX hydrolase
GGC04_RS25340	COG1742	UPF0060 membrane protein
GGC04_RS25345	COG0251	oxidation-reduction process
GGC04_RS25355	COG0583	DNA-binding transcription factor activity
GGC04_RS25385	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GGC04_RS25390	COG1051	belongs to the nudix hydrolase family
GGC04_RS25425	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
GGC04_RS25425	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GGC04_RS25440	COG1028	Short-chain dehydrogenase reductase Sdr
GGC04_RS25450	COG2274	protein secretion by the type I secretion system
GGC04_RS25460	COG2274	protein secretion by the type I secretion system
GGC04_RS25470	COG0583	DNA-binding transcription factor activity
GGC04_RS25500	COG1280	lysine exporter protein (LysE YggA)
GGC04_RS25505	COG1917	Cupin 2, conserved barrel domain protein
GGC04_RS25505	COG2207	Transcriptional regulator
GGC04_RS25525	COG0625	glutathione transferase activity
GGC04_RS25530	COG0583	DNA-binding transcription factor activity
GGC04_RS25555	COG1917	Cupin 2, conserved barrel domain protein
GGC04_RS25555	COG2207	Transcriptional regulator
GGC04_RS25565	COG4608	Belongs to the ABC transporter superfamily
GGC04_RS25570	COG0444	Belongs to the ABC transporter superfamily
GGC04_RS25575	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GGC04_RS25595	COG1609	Transcriptional regulator
GGC04_RS25605	COG4580	involved in the transport of maltose and maltodextrins
GGC04_RS25615	COG1472	Belongs to the glycosyl hydrolase 3 family
GGC04_RS25635	COG0071	Belongs to the small heat shock protein (HSP20) family
GGC04_RS25640	COG0459	protein refolding
GGC04_RS25645	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GGC04_RS25665	COG1917	Cupin 2, conserved barrel domain protein
GGC04_RS25665	COG2169	Transcriptional regulator
GGC04_RS25720	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
GGC04_RS25730	COG1335	isochorismatase
GGC04_RS25735	COG2169	Transcriptional regulator
GGC04_RS25760	COG2267	carboxylic ester hydrolase activity
GGC04_RS25795	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GGC04_RS25805	COG2203	Gaf domain
GGC04_RS25805	COG3706	GGDEF domain
GGC04_RS25805	COG4251	negative regulation of phosphorylation
GGC04_RS25805	COG5001	Diguanylate cyclase
GGC04_RS25845	COG2003	Belongs to the UPF0758 family
GGC04_RS25955	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GGC04_RS26085	COG4771	TonB-dependent receptor
GGC04_RS26095	COG4974	Belongs to the 'phage' integrase family
GGC04_RS26105	COG1028	Short-chain dehydrogenase reductase Sdr
GGC04_RS26110	COG0583	DNA-binding transcription factor activity
GGC04_RS26150	COG2026	Addiction module toxin, RelE StbE family
GGC04_RS26200	COG1609	Transcriptional regulator
GGC04_RS26210	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GGC04_RS26220	COG1280	lysine exporter protein (LysE YggA)
GGC04_RS26225	COG0735	belongs to the Fur family
GGC04_RS26340	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GGC04_RS26340	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GGC04_RS26350	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
GGC04_RS26370	COG1181	Belongs to the D-alanine--D-alanine ligase family
GGC04_RS26375	COG4191	Histidine kinase
GGC04_RS26440	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GGC04_RS26455	COG1192	Involved in chromosome partitioning
GGC04_RS26465	COG2814	Major facilitator Superfamily
GGC04_RS26520	COG4191	Histidine kinase
GGC04_RS26525	COG5001	Diguanylate cyclase
GGC04_RS26525	COG3300	MHYT domain
GGC04_RS26595	COG2247	cell wall binding repeat
GGC04_RS26595	COG0860	N-Acetylmuramoyl-L-alanine amidase
GGC04_RS26635	COG3093	addiction module antidote protein HigA
GGC04_RS26640	COG3549	Plasmid maintenance system killer
GGC04_RS26675	COG5301	cellulose 1,4-beta-cellobiosidase activity
GGC04_RS26860	COG0629	single-stranded DNA binding
GGC04_RS26900	COG0776	regulation of translation
GGC04_RS27010	COG1959	2 iron, 2 sulfur cluster binding