locus-tag	class	description
FIU99_RS00010	COG0592	DNA-directed DNA polymerase activity
FIU99_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FIU99_RS00020	COG0187	DNA topoisomerase II activity
FIU99_RS00025	COG0071	Belongs to the small heat shock protein (HSP20) family
FIU99_RS00030	COG3977	Valine--pyruvate aminotransferase
FIU99_RS00035	COG0751	glycine-tRNA ligase activity
FIU99_RS00040	COG0752	glycyl-tRNA synthetase alpha subunit
FIU99_RS00045	COG2119	membrane
FIU99_RS00055	COG0425	Belongs to the sulfur carrier protein TusA family
FIU99_RS00070	COG0604	alcohol dehydrogenase
FIU99_RS00080	COG0129	dihydroxy-acid dehydratase activity
FIU99_RS00085	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FIU99_RS00090	COG3978	acetolactate synthase activity
FIU99_RS00100	COG0606	chelatase, subunit chli
FIU99_RS00185	COG0204	Acyl-transferase
FIU99_RS00190	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FIU99_RS00195	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FIU99_RS00205	COG3084	Protein conserved in bacteria
FIU99_RS00210	COG4326	sporulation control protein
FIU99_RS00215	COG1272	protein, Hemolysin III
FIU99_RS00225	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FIU99_RS00230	COG0569	domain protein
FIU99_RS00235	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FIU99_RS00235	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FIU99_RS00245	COG0242	peptide deformylase activity
FIU99_RS00250	COG0758	DNA mediated transformation
FIU99_RS00255	COG2922	Belongs to the Smg family
FIU99_RS00260	COG0551	DNA topoisomerase type I activity
FIU99_RS00265	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FIU99_RS00270	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FIU99_RS00280	COG0408	coproporphyrinogen oxidase activity
FIU99_RS00295	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FIU99_RS00335	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FIU99_RS00345	COG2204	response regulator
FIU99_RS00350	COG3852	Histidine kinase
FIU99_RS00355	COG0174	glutamine synthetase
FIU99_RS00360	COG1217	gtp-binding protein TYPA
FIU99_RS00370	COG1295	ribonuclease BN
FIU99_RS00375	COG1490	D-aminoacyl-tRNA deacylase activity
FIU99_RS00380	COG0456	acetyltransferase
FIU99_RS00390	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FIU99_RS00400	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FIU99_RS00405	COG3031	protein transport across the cell outer membrane
FIU99_RS00415	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FIU99_RS00420	COG1459	type II secretion system
FIU99_RS00425	COG2165	general secretion pathway protein
FIU99_RS00430	COG2165	general secretion pathway protein
FIU99_RS00435	COG2165	general secretion pathway protein
FIU99_RS00440	COG4795	General secretion pathway protein
FIU99_RS00445	COG3156	type II secretion system protein K
FIU99_RS00450	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
FIU99_RS00455	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
FIU99_RS00475	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FIU99_RS00485	COG2183	response to ionizing radiation
FIU99_RS00495	COG0596	Alpha beta hydrolase
FIU99_RS00505	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FIU99_RS00505	COG0316	Belongs to the HesB IscA family
FIU99_RS00510	COG0494	nUDIX hydrolase
FIU99_RS00515	COG1218	3'(2'),5'-bisphosphate nucleotidase
FIU99_RS00520	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FIU99_RS00525	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FIU99_RS00530	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FIU99_RS00535	COG1758	RNA polymerase activity
FIU99_RS00540	COG0194	GDP metabolic process
FIU99_RS00545	COG1595	DNA-templated transcription, initiation
FIU99_RS00575	COG0848	biopolymer transport protein
FIU99_RS00585	COG2252	PERMEase
FIU99_RS00590	COG2831	hemolysin activation secretion protein
FIU99_RS00595	COG3210	domain, Protein
FIU99_RS00605	COG1561	YicC-like family, N-terminal region
FIU99_RS00610	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FIU99_RS00615	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FIU99_RS00620	COG1560	Kdo2-lipid A biosynthetic process
FIU99_RS00625	COG1560	Kdo2-lipid A biosynthetic process
FIU99_RS00630	COG1309	transcriptional regulator
FIU99_RS00635	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FIU99_RS00640	COG2003	Belongs to the UPF0758 family
FIU99_RS00645	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FIU99_RS00665	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FIU99_RS00670	COG0859	PFAM glycosyl transferase family 9
FIU99_RS00675	COG0463	Glycosyl transferase, family 2
FIU99_RS00680	COG0859	PFAM glycosyl transferase family 9
FIU99_RS00685	COG3642	lipopolysaccharide core region biosynthetic process
FIU99_RS00700	COG1519	Transferase
FIU99_RS00715	COG0859	PFAM glycosyl transferase family 9
FIU99_RS00745	COG1086	Polysaccharide biosynthesis protein
FIU99_RS00750	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FIU99_RS00760	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
FIU99_RS00765	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FIU99_RS00775	COG2089	acid synthase
FIU99_RS00785	COG0318	PFAM AMP-dependent synthetase and ligase
FIU99_RS00795	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
FIU99_RS00810	COG4310	Domain of unknown function (DUF2172)
FIU99_RS00820	COG2226	methyltransferase
FIU99_RS00860	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FIU99_RS00865	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FIU99_RS00870	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FIU99_RS00870	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FIU99_RS00875	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FIU99_RS00915	COG1494	fructose-1,6-bisphosphatase
FIU99_RS00920	COG3074	FtsZ-dependent cytokinesis
FIU99_RS00925	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FIU99_RS00930	COG0460	homoserine dehydrogenase
FIU99_RS00930	COG0527	aspartate kinase activity
FIU99_RS00935	COG0626	cystathionine gamma-synthase activity
FIU99_RS00940	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
FIU99_RS00945	COG0281	malic enzyme
FIU99_RS00955	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FIU99_RS00960	COG1609	Transcriptional regulator
FIU99_RS00965	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FIU99_RS00970	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FIU99_RS00995	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FIU99_RS01000	COG1053	succinate dehydrogenase
FIU99_RS01005	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
FIU99_RS01010	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FIU99_RS01045	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FIU99_RS01060	COG1045	serine acetyltransferase
FIU99_RS01065	COG1695	Transcriptional regulator
FIU99_RS01070	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FIU99_RS01075	COG1573	uracil-dna glycosylase
FIU99_RS01080	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FIU99_RS01090	COG1253	flavin adenine dinucleotide binding
FIU99_RS01105	COG0151	Belongs to the GarS family
FIU99_RS01120	COG0789	Transcriptional regulator
FIU99_RS01125	COG2199	diguanylate cyclase activity
FIU99_RS01130	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FIU99_RS01135	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FIU99_RS01140	COG2264	protein methyltransferase activity
FIU99_RS01145	COG0439	Biotin carboxylase
FIU99_RS01150	COG0511	ligase activity, forming carbon-carbon bonds
FIU99_RS01155	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FIU99_RS01160	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FIU99_RS01175	COG2814	Major facilitator Superfamily
FIU99_RS01180	COG0784	Response regulator, receiver
FIU99_RS01180	COG2205	protein histidine kinase activity
FIU99_RS01190	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FIU99_RS01200	COG2095	MarC family integral membrane protein
FIU99_RS01210	COG4232	protein-disulfide reductase activity
FIU99_RS01215	COG1438	arginine binding
FIU99_RS01220	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
FIU99_RS01225	COG0540	Belongs to the ATCase OTCase family
FIU99_RS01230	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FIU99_RS01245	COG1288	antiporter activity
FIU99_RS01250	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FIU99_RS01255	COG1027	Aspartate ammonia-lyase
FIU99_RS01335	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FIU99_RS01345	COG1012	belongs to the aldehyde dehydrogenase family
FIU99_RS01355	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FIU99_RS01360	COG3954	Phosphoribulokinase
FIU99_RS01370	COG0429	hydrolase of the alpha beta-hydrolase fold
FIU99_RS01380	COG0488	(ABC) transporter
FIU99_RS01400	COG1047	Peptidyl-prolyl cis-trans
FIU99_RS01410	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FIU99_RS01420	COG0402	S-adenosylhomocysteine deaminase activity
FIU99_RS01425	COG0557	exoribonuclease II activity
FIU99_RS01430	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FIU99_RS01435	COG0051	transcription antitermination factor activity, RNA binding
FIU99_RS01440	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FIU99_RS01445	COG0088	Forms part of the polypeptide exit tunnel
FIU99_RS01460	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FIU99_RS01465	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FIU99_RS01470	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FIU99_RS01485	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FIU99_RS01500	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FIU99_RS01515	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FIU99_RS01530	COG1841	ribosomal large subunit assembly
FIU99_RS01535	COG0200	Binds to the 23S rRNA
FIU99_RS01540	COG0201	protein transport
FIU99_RS01545	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FIU99_RS01550	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FIU99_RS01555	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FIU99_RS01565	COG0202	RNA polymerase activity
FIU99_RS01570	COG0203	ribosomal protein L17
FIU99_RS01580	COG0545	Peptidyl-prolyl cis-trans isomerase
FIU99_RS01595	COG2153	protein acetylation
FIU99_RS01605	COG0737	Belongs to the 5'-nucleotidase family
FIU99_RS01610	COG1648	precorrin-2 dehydrogenase activity
FIU99_RS01610	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FIU99_RS01625	COG3273	potassium ion transport
FIU99_RS01625	COG0471	metal ion transport
FIU99_RS01630	COG0529	Catalyzes the synthesis of activated sulfate
FIU99_RS01640	COG0735	belongs to the Fur family
FIU99_RS01650	COG3437	response regulator, receiver
FIU99_RS01685	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FIU99_RS01690	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FIU99_RS01695	COG0175	sulfate reduction
FIU99_RS01750	COG1410	methionine synthase
FIU99_RS01750	COG0646	methionine synthase
FIU99_RS01755	COG2239	Acts as a magnesium transporter
FIU99_RS01760	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FIU99_RS01765	COG1660	Displays ATPase and GTPase activities
FIU99_RS01770	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FIU99_RS01775	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FIU99_RS01785	COG1137	ATPase activity
FIU99_RS01790	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FIU99_RS01800	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FIU99_RS01805	COG0517	IMP dehydrogenase activity
FIU99_RS01805	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FIU99_RS01815	COG1127	ABC transporter
FIU99_RS01820	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FIU99_RS01825	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FIU99_RS01830	COG2854	intermembrane phospholipid transfer
FIU99_RS01840	COG5007	Belongs to the BolA IbaG family
FIU99_RS01850	COG0204	Acyl-transferase
FIU99_RS01855	COG2235	arginine
FIU99_RS01875	COG0589	response to stress
FIU99_RS01885	COG2358	TRAP transporter, solute receptor (TAXI family
FIU99_RS01895	COG1438	arginine binding
FIU99_RS01900	COG0039	L-malate dehydrogenase activity
FIU99_RS01910	COG0251	oxidation-reduction process
FIU99_RS01915	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
FIU99_RS01930	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FIU99_RS01935	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FIU99_RS01945	COG0564	pseudouridine synthase activity
FIU99_RS01950	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FIU99_RS01960	COG4269	membrane
FIU99_RS01970	COG0525	valine-tRNA ligase activity
FIU99_RS01975	COG2927	DNA polymerase III (CHI subunit)
FIU99_RS01985	COG0795	lipopolysaccharide-transporting ATPase activity
FIU99_RS01990	COG0795	lipopolysaccharide-transporting ATPase activity
FIU99_RS01995	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FIU99_RS02000	COG1546	Belongs to the CinA family
FIU99_RS02005	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FIU99_RS02010	COG2137	regulation of response to DNA damage stimulus
FIU99_RS02020	COG0527	aspartate kinase activity
FIU99_RS02070	COG3630	sodium ion export across plasma membrane
FIU99_RS02075	COG5016	pyruvate
FIU99_RS02075	COG0511	ligase activity, forming carbon-carbon bonds
FIU99_RS02080	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
FIU99_RS02090	COG1238	metal cluster binding
FIU99_RS02095	COG0612	Peptidase, M16
FIU99_RS02100	COG2918	glutathione biosynthetic process
FIU99_RS02110	COG1854	S-ribosylhomocysteine lyase activity
FIU99_RS02125	COG0582	viral genome integration into host DNA
FIU99_RS02155	COG0328	RNA-DNA hybrid ribonuclease activity
FIU99_RS02195	COG5001	Diguanylate cyclase
FIU99_RS02195	COG2203	Gaf domain
FIU99_RS02195	COG4251	negative regulation of phosphorylation
FIU99_RS02195	COG3706	GGDEF domain
FIU99_RS02205	COG1879	ABC-type sugar transport system periplasmic component
FIU99_RS02210	COG0840	transmembrane signaling receptor activity
FIU99_RS02225	COG0840	transmembrane signaling receptor activity
FIU99_RS02230	COG5001	Diguanylate cyclase
FIU99_RS02230	COG3706	GGDEF domain
FIU99_RS02230	COG4251	negative regulation of phosphorylation
FIU99_RS02230	COG2203	Gaf domain
FIU99_RS02255	COG0640	Transcriptional regulator
FIU99_RS02300	COG2003	Belongs to the UPF0758 family
FIU99_RS02310	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FIU99_RS02335	COG3437	response regulator, receiver
FIU99_RS02400	COG0473	3-isopropylmalate dehydrogenase activity
FIU99_RS02405	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FIU99_RS02425	COG0583	DNA-binding transcription factor activity
FIU99_RS02430	COG1022	Amp-dependent synthetase and ligase
FIU99_RS02435	COG0028	Belongs to the TPP enzyme family
FIU99_RS02440	COG0440	acetolactate synthase activity
FIU99_RS02445	COG0584	glycerophosphoryl diester phosphodiesterase
FIU99_RS02450	COG2271	Major facilitator Superfamily
FIU99_RS02455	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FIU99_RS02465	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FIU99_RS02475	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
FIU99_RS02480	COG3079	Belongs to the UPF0149 family
FIU99_RS02485	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FIU99_RS02490	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FIU99_RS02515	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FIU99_RS02520	COG1595	DNA-templated transcription, initiation
FIU99_RS02535	COG3086	response to oxidative stress
FIU99_RS02540	COG0481	GTPase activity
FIU99_RS02550	COG0571	ribonuclease III activity
FIU99_RS02555	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FIU99_RS02560	COG1381	Involved in DNA repair and RecF pathway recombination
FIU99_RS02565	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FIU99_RS02570	COG0736	holo-[acyl-carrier-protein] synthase activity
FIU99_RS02575	COG2205	protein histidine kinase activity
FIU99_RS02575	COG4999	Histidine kinase
FIU99_RS02575	COG3437	response regulator, receiver
FIU99_RS02575	COG3850	Histidine kinase
FIU99_RS02580	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FIU99_RS02585	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FIU99_RS02590	COG3956	TIGRFAM MazG family protein
FIU99_RS02600	COG0148	phosphopyruvate hydratase activity
FIU99_RS02605	COG0617	tRNA 3'-terminal CCA addition
FIU99_RS02610	COG3267	Type II secretory pathway component ExeA
FIU99_RS02610	COG3409	Peptidoglycan-binding domain 1 protein
FIU99_RS02620	COG4991	sh3 domain protein
FIU99_RS02625	COG0306	phosphate transporter
FIU99_RS02630	COG1392	Phosphate transport regulator
FIU99_RS02635	COG3025	triphosphatase activity
FIU99_RS02640	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FIU99_RS02650	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FIU99_RS02655	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FIU99_RS02655	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FIU99_RS02660	COG0745	RESPONSE REGULATOR receiver
FIU99_RS02675	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FIU99_RS02695	COG0083	homoserine kinase activity
FIU99_RS02700	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FIU99_RS02705	COG2860	membrane
FIU99_RS02710	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FIU99_RS02715	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
FIU99_RS02725	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FIU99_RS02740	COG1846	Transcriptional regulator
FIU99_RS02745	COG0534	Mate efflux family protein
FIU99_RS02750	COG2204	response regulator
FIU99_RS02760	COG0667	Aldo Keto reductase
FIU99_RS02770	COG3066	DNA modification
FIU99_RS02775	COG0494	nUDIX hydrolase
FIU99_RS02785	COG0730	response to heat
FIU99_RS02790	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FIU99_RS02795	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FIU99_RS02800	COG1283	sodium-dependent phosphate transmembrane transporter activity
FIU99_RS02805	COG0583	DNA-binding transcription factor activity
FIU99_RS02810	COG0640	Transcriptional regulator
FIU99_RS02815	COG0268	Binds directly to 16S ribosomal RNA
FIU99_RS02820	COG0728	peptidoglycan biosynthetic process
FIU99_RS02825	COG0196	riboflavin kinase activity
FIU99_RS02840	COG1047	Peptidyl-prolyl cis-trans
FIU99_RS02845	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FIU99_RS02850	COG1966	Carbon starvation protein
FIU99_RS02860	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FIU99_RS02865	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FIU99_RS02870	COG2971	BadF BadG BcrA BcrD
FIU99_RS02880	COG1737	Transcriptional regulator
FIU99_RS02890	COG3279	Response regulator of the LytR AlgR family
FIU99_RS02895	COG3275	phosphorelay sensor kinase activity
FIU99_RS02900	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FIU99_RS02905	COG1605	Chorismate mutase
FIU99_RS02905	COG0287	Prephenate dehydrogenase
FIU99_RS02910	COG0739	heme binding
FIU99_RS02920	COG0488	(ABC) transporter
FIU99_RS02925	COG0741	lytic transglycosylase activity
FIU99_RS02930	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
FIU99_RS02940	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
FIU99_RS02945	COG5001	Diguanylate cyclase
FIU99_RS02950	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FIU99_RS02955	COG0077	Prephenate dehydratase
FIU99_RS02955	COG1605	Chorismate mutase
FIU99_RS02960	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FIU99_RS02965	COG0741	lytic transglycosylase activity
FIU99_RS02970	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FIU99_RS02975	COG0564	pseudouridine synthase activity
FIU99_RS02985	COG0542	response to heat
FIU99_RS03030	COG0483	inositol monophosphate 1-phosphatase activity
FIU99_RS03040	COG1959	2 iron, 2 sulfur cluster binding
FIU99_RS03050	COG0822	iron-sulfur transferase activity
FIU99_RS03070	COG0633	Ferredoxin
FIU99_RS03075	COG2975	iron-sulfur cluster assembly
FIU99_RS03080	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FIU99_RS03090	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FIU99_RS03095	COG0583	DNA-binding transcription factor activity
FIU99_RS03105	COG0583	DNA-binding transcription factor activity
FIU99_RS03110	COG1022	Amp-dependent synthetase and ligase
FIU99_RS03115	COG2169	Transcriptional regulator
FIU99_RS03140	COG4964	Belongs to the GSP D family
FIU99_RS03190	COG2169	Transcriptional regulator
FIU99_RS03195	COG1486	melibiose metabolic process
FIU99_RS03200	COG2211	Major facilitator Superfamily
FIU99_RS03210	COG3408	Glycogen debranching enzyme
FIU99_RS03210	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
FIU99_RS03225	COG1309	transcriptional regulator
FIU99_RS03230	COG0531	amino acid
FIU99_RS03235	COG2731	YhcH YjgK YiaL family protein
FIU99_RS03240	COG3250	beta-galactosidase activity
FIU99_RS03245	COG1609	Transcriptional regulator
FIU99_RS03250	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FIU99_RS03255	COG1085	galactose-1-phosphate uridylyltransferase
FIU99_RS03265	COG2017	converts alpha-aldose to the beta-anomer
FIU99_RS03275	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FIU99_RS03285	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FIU99_RS03285	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FIU99_RS03285	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FIU99_RS03290	COG2207	Transcriptional regulator
FIU99_RS03300	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FIU99_RS03310	COG2171	N-acyltransferase activity
FIU99_RS03315	COG0450	alkyl hydroperoxide reductase
FIU99_RS03320	COG0583	DNA-binding transcription factor activity
FIU99_RS03325	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FIU99_RS03350	COG0517	IMP dehydrogenase activity
FIU99_RS03355	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FIU99_RS03365	COG1862	Preprotein translocase
FIU99_RS03370	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FIU99_RS03375	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FIU99_RS03390	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
FIU99_RS03395	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FIU99_RS03400	COG0826	peptidase U32
FIU99_RS03415	COG0745	RESPONSE REGULATOR receiver
FIU99_RS03420	COG5002	protein histidine kinase activity
FIU99_RS03430	COG0248	Ppx GppA phosphatase
FIU99_RS03435	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FIU99_RS03440	COG0573	inorganic phosphate transmembrane transporter activity
FIU99_RS03445	COG0581	inorganic phosphate transmembrane transporter activity
FIU99_RS03450	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FIU99_RS03455	COG0704	Plays a role in the regulation of phosphate uptake
FIU99_RS03470	COG3141	response to X-ray
FIU99_RS03475	COG1309	transcriptional regulator
FIU99_RS03480	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FIU99_RS03500	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FIU99_RS03505	COG1074	ATP-dependent DNA helicase activity
FIU99_RS03510	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FIU99_RS03530	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FIU99_RS03535	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FIU99_RS03540	COG2166	iron-sulfur cluster assembly
FIU99_RS03550	COG1426	Protein conserved in bacteria
FIU99_RS03555	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FIU99_RS03560	COG0124	histidyl-tRNA synthetase
FIU99_RS03565	COG2976	Protein conserved in bacteria
FIU99_RS03570	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FIU99_RS03575	COG1160	GTP binding
FIU99_RS03585	COG2203	Gaf domain
FIU99_RS03585	COG2199	diguanylate cyclase activity
FIU99_RS03600	COG0516	GMP reductase activity
FIU99_RS03600	COG0517	IMP dehydrogenase activity
FIU99_RS03615	COG1584	GPR1 FUN34 yaaH family protein
FIU99_RS03620	COG1115	amino acid carrier protein
FIU99_RS03625	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FIU99_RS03645	COG2873	o-acetylhomoserine
FIU99_RS03650	COG0784	Response regulator, receiver
FIU99_RS03650	COG0835	chemotaxis
FIU99_RS03655	COG0204	Acyl-transferase
FIU99_RS03675	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FIU99_RS03680	COG0668	transmembrane transport
FIU99_RS03705	COG2867	negative regulation of translational initiation
FIU99_RS03710	COG2914	Belongs to the UPF0125 (RnfH) family
FIU99_RS03715	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FIU99_RS03720	COG0497	DNA recombination
FIU99_RS03725	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FIU99_RS03730	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FIU99_RS03735	COG1301	dicarboxylic acid transport
FIU99_RS03740	COG0443	Heat shock 70 kDa protein
FIU99_RS03755	COG4970	Tfp pilus assembly protein FimT
FIU99_RS03775	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
FIU99_RS03785	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FIU99_RS03790	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FIU99_RS03790	COG0047	phosphoribosylformylglycinamidine synthase activity
FIU99_RS03815	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FIU99_RS03820	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FIU99_RS03825	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FIU99_RS03830	COG1187	pseudouridine synthase activity
FIU99_RS03835	COG2840	Smr protein MutS2
FIU99_RS03860	COG3104	oligopeptide transport
FIU99_RS03865	COG0367	asparagine synthase
FIU99_RS03870	COG4651	solute:proton antiporter activity
FIU99_RS03870	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FIU99_RS03875	COG1940	carbohydrate kinase activity
FIU99_RS03875	COG1846	Transcriptional regulator
FIU99_RS03880	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FIU99_RS03885	COG1263	PTS System
FIU99_RS03885	COG2190	(PTS) system
FIU99_RS03885	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FIU99_RS03915	COG0596	Alpha beta hydrolase
FIU99_RS03920	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
FIU99_RS03925	COG0033	Phosphoglucomutase
FIU99_RS03935	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FIU99_RS03950	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FIU99_RS03955	COG1053	succinate dehydrogenase
FIU99_RS03960	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FIU99_RS03965	COG0567	Dehydrogenase, E1 component
FIU99_RS03970	COG0508	dehydrogenase complex catalyzes the overall conversion of
FIU99_RS04010	COG3098	single-species biofilm formation
FIU99_RS04015	COG0564	pseudouridine synthase activity
FIU99_RS04025	COG0142	geranyltranstransferase activity
FIU99_RS04030	COG1722	exodeoxyribonuclease VII activity
FIU99_RS04035	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FIU99_RS04045	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FIU99_RS04045	COG0301	tRNA thio-modification
FIU99_RS04050	COG0583	DNA-binding transcription factor activity
FIU99_RS04065	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
FIU99_RS04075	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FIU99_RS04080	COG1611	Belongs to the LOG family
FIU99_RS04095	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FIU99_RS04095	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FIU99_RS04105	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
FIU99_RS04120	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FIU99_RS04125	COG1393	Belongs to the ArsC family
FIU99_RS04150	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
FIU99_RS04155	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
FIU99_RS04160	COG0437	4 iron, 4 sulfur cluster binding
FIU99_RS04165	COG3301	Polysulphide reductase, NrfD
FIU99_RS04170	COG1138	Cytochrome C-type biogenesis protein
FIU99_RS04175	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FIU99_RS04180	COG4235	cytochrome complex assembly
FIU99_RS04180	COG3088	subunit of a heme lyase
FIU99_RS04190	COG2837	iron assimilation
FIU99_RS04205	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FIU99_RS04215	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FIU99_RS04225	COG1516	flagellar protein fliS
FIU99_RS04245	COG1677	Flagellar hook-basal body complex protein FliE
FIU99_RS04255	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FIU99_RS04305	COG1987	bacterial-type flagellum assembly
FIU99_RS04310	COG1684	flagellar biosynthetic protein fliR
FIU99_RS04325	COG2890	protein-(glutamine-N5) methyltransferase activity
FIU99_RS04330	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FIU99_RS04340	COG2860	membrane
FIU99_RS04345	COG3101	peptidyl-lysine hydroxylation
FIU99_RS04375	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FIU99_RS04385	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FIU99_RS04390	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FIU99_RS04400	COG0101	tRNA pseudouridine synthase activity
FIU99_RS04405	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FIU99_RS04410	COG0285	dihydrofolate synthase activity
FIU99_RS04415	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
FIU99_RS04420	COG1286	toxin biosynthetic process
FIU99_RS04425	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FIU99_RS04430	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FIU99_RS04435	COG1121	(ABC) transporter
FIU99_RS04440	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
FIU99_RS04445	COG4977	sequence-specific DNA binding
FIU99_RS04450	COG1918	ferrous iron import across plasma membrane
FIU99_RS04455	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FIU99_RS04470	COG0018	arginyl-trna synthetase
FIU99_RS04475	COG3102	Protein conserved in bacteria
FIU99_RS04480	COG1025	Belongs to the peptidase M16 family
FIU99_RS04485	COG2062	phosphohistidine phosphatase, SixA
FIU99_RS04515	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
FIU99_RS04520	COG0784	Response regulator, receiver
FIU99_RS04520	COG0643	Histidine kinase
FIU99_RS04520	COG2198	Histidine kinase
FIU99_RS04525	COG2201	protein-glutamate methylesterase activity
FIU99_RS04530	COG1192	Involved in chromosome partitioning
FIU99_RS04540	COG0835	chemotaxis
FIU99_RS04550	COG4133	protoheme IX ABC transporter activity
FIU99_RS04555	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FIU99_RS04560	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FIU99_RS04565	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FIU99_RS04575	COG1138	Cytochrome C-type biogenesis protein
FIU99_RS04580	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FIU99_RS04585	COG3088	subunit of a heme lyase
FIU99_RS04585	COG4235	cytochrome complex assembly
FIU99_RS04595	COG2853	Lipoprotein
FIU99_RS04600	COG2067	long-chain fatty acid transport protein
FIU99_RS04605	COG2067	long-chain fatty acid transport protein
FIU99_RS04620	COG0183	Belongs to the thiolase family
FIU99_RS04630	COG0778	Nitroreductase
FIU99_RS04635	COG0583	DNA-binding transcription factor activity
FIU99_RS04640	COG0745	RESPONSE REGULATOR receiver
FIU99_RS04650	COG2832	Protein of unknown function (DUF454)
FIU99_RS04655	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FIU99_RS04670	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FIU99_RS04705	COG1653	transport
FIU99_RS04710	COG1175	transmembrane transport
FIU99_RS04720	COG3842	ATPase activity
FIU99_RS04725	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FIU99_RS04730	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FIU99_RS04735	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FIU99_RS04745	COG2204	response regulator
FIU99_RS04770	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FIU99_RS04775	COG0776	regulation of translation
FIU99_RS04780	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FIU99_RS04785	COG1555	photosystem II stabilization
FIU99_RS04795	COG0539	negative regulation of cytoplasmic translation
FIU99_RS04805	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
FIU99_RS04810	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
FIU99_RS04815	COG0284	orotidine-5'-phosphate decarboxylase activity
FIU99_RS04850	COG4120	Belongs to the binding-protein-dependent transport system permease family
FIU99_RS04860	COG3706	GGDEF domain
FIU99_RS04865	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FIU99_RS04885	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FIU99_RS04890	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FIU99_RS04900	COG0252	asparaginase activity
FIU99_RS04905	COG0616	signal peptide processing
FIU99_RS04910	COG0446	pyridine nucleotide-disulphide oxidoreductase
FIU99_RS04910	COG1902	pentaerythritol trinitrate reductase activity
FIU99_RS04915	COG0788	formyltetrahydrofolate deformylase activity
FIU99_RS04925	COG1199	ATP-dependent helicase activity
FIU99_RS04930	COG1214	PFAM Peptidase M22, glycoprotease
FIU99_RS04945	COG2267	carboxylic ester hydrolase activity
FIU99_RS04950	COG0318	PFAM AMP-dependent synthetase and ligase
FIU99_RS04955	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FIU99_RS04960	COG0659	secondary active sulfate transmembrane transporter activity
FIU99_RS04965	COG1530	ribonuclease E activity
FIU99_RS04970	COG0564	pseudouridine synthase activity
FIU99_RS04975	COG0424	maF-like protein
FIU99_RS04980	COG1399	metal-binding, possibly nucleic acid-binding protein
FIU99_RS04985	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FIU99_RS04995	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FIU99_RS05020	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FIU99_RS05025	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FIU99_RS05030	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FIU99_RS05035	COG0470	DNA polymerase III
FIU99_RS05040	COG0084	hydrolase, TatD family'
FIU99_RS05045	COG1263	PTS System
FIU99_RS05045	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FIU99_RS05065	COG0733	neurotransmitter:sodium symporter activity
FIU99_RS05080	COG4667	esterase of the alpha-beta hydrolase superfamily
FIU99_RS05085	COG0469	pyruvate kinase activity
FIU99_RS05090	COG1940	carbohydrate kinase activity
FIU99_RS05095	COG0784	Response regulator, receiver
FIU99_RS05095	COG0835	chemotaxis
FIU99_RS05115	COG1028	Short-chain dehydrogenase reductase Sdr
FIU99_RS05120	COG0616	signal peptide processing
FIU99_RS05125	COG0513	Belongs to the DEAD box helicase family
FIU99_RS05140	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FIU99_RS05145	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FIU99_RS05155	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
FIU99_RS05160	COG0436	Aminotransferase
FIU99_RS05165	COG1169	isochorismate synthase
FIU99_RS05170	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
FIU99_RS05175	COG0596	Alpha beta hydrolase
FIU99_RS05195	COG2855	membrane
FIU99_RS05200	COG0477	Major facilitator Superfamily
FIU99_RS05225	COG1522	sequence-specific DNA binding
FIU99_RS05240	COG1946	Acyl-CoA thioesterase
FIU99_RS05245	COG3126	Type III secretion system lipoprotein chaperone (YscW)
FIU99_RS05260	COG3706	GGDEF domain
FIU99_RS05305	COG1414	Transcriptional regulator
FIU99_RS05310	COG0280	phosphate acetyltransferase
FIU99_RS05315	COG0730	response to heat
FIU99_RS05335	COG2855	membrane
FIU99_RS05350	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FIU99_RS05355	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FIU99_RS05360	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FIU99_RS05365	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FIU99_RS05365	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FIU99_RS05380	COG1472	Belongs to the glycosyl hydrolase 3 family
FIU99_RS05385	COG3876	Protein conserved in bacteria
FIU99_RS05395	COG1215	transferase activity, transferring glycosyl groups
FIU99_RS05415	COG1770	oligopeptidase
FIU99_RS05425	COG3227	Zinc metalloprotease (Elastase)
FIU99_RS05435	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FIU99_RS05445	COG0577	efflux transmembrane transporter activity
FIU99_RS05455	COG0577	efflux transmembrane transporter activity
FIU99_RS05455	COG1136	(ABC) transporter
FIU99_RS05475	COG0330	HflC and HflK could
FIU99_RS05485	COG0840	transmembrane signaling receptor activity
FIU99_RS05490	COG1404	Belongs to the peptidase S8 family
FIU99_RS05520	COG2067	long-chain fatty acid transport protein
FIU99_RS05535	COG0601	transmembrane transport
FIU99_RS05540	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FIU99_RS05545	COG0444	Belongs to the ABC transporter superfamily
FIU99_RS05555	COG0435	Glutathione S-transferase
FIU99_RS05565	COG0857	belongs to the CobB CobQ family
FIU99_RS05565	COG0280	phosphate acetyltransferase
FIU99_RS05570	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FIU99_RS05575	COG3092	negative regulation of chromosome organization
FIU99_RS05580	COG0686	Belongs to the AlaDH PNT family
FIU99_RS05590	COG1674	ftsk spoiiie
FIU99_RS05600	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FIU99_RS05610	COG2186	Transcriptional regulator
FIU99_RS05625	COG0537	adenosine 5'-monophosphoramidase activity
FIU99_RS05655	COG1252	NADH dehydrogenase
FIU99_RS05680	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FIU99_RS05690	COG4591	ABC-type transport system involved in lipoprotein release permease component
FIU99_RS05695	COG1136	(ABC) transporter
FIU99_RS05700	COG4591	ABC-type transport system involved in lipoprotein release permease component
FIU99_RS05710	COG2333	competence protein COMEC
FIU99_RS05710	COG0658	competence protein
FIU99_RS05715	COG1132	(ABC) transporter
FIU99_RS05725	COG2835	tetraacyldisaccharide 4'-kinase activity
FIU99_RS05730	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FIU99_RS05735	COG2719	SpoVR family
FIU99_RS05740	COG2718	Belongs to the UPF0229 family
FIU99_RS05745	COG2766	serine protein kinase
FIU99_RS05750	COG3713	MltA-interacting MipA family protein
FIU99_RS05755	COG3013	Belongs to the UPF0304 family
FIU99_RS05765	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FIU99_RS05780	COG1882	Formate acetyltransferase
FIU99_RS05815	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FIU99_RS05955	COG3772	lysozyme
FIU99_RS05970	COG4695	Portal protein
FIU99_RS06010	COG4386	tail sheath protein
FIU99_RS06045	COG3646	Phage regulatory protein
FIU99_RS06070	COG1454	alcohol dehydrogenase
FIU99_RS06070	COG1012	belongs to the aldehyde dehydrogenase family
FIU99_RS06075	COG1737	Transcriptional regulator
FIU99_RS06080	COG0076	glutamate decarboxylase activity
FIU99_RS06090	COG2431	L-lysine efflux transmembrane transporter activity
FIU99_RS06100	COG3070	regulator of competence-specific genes
FIU99_RS06115	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FIU99_RS06115	COG4191	Histidine kinase
FIU99_RS06125	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FIU99_RS06135	COG1032	radical SAM domain protein
FIU99_RS06160	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FIU99_RS06165	COG1764	response to oxidative stress
FIU99_RS06170	COG1846	Transcriptional regulator
FIU99_RS06180	COG0583	DNA-binding transcription factor activity
FIU99_RS06190	COG0673	inositol 2-dehydrogenase activity
FIU99_RS06195	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FIU99_RS06215	COG0840	transmembrane signaling receptor activity
FIU99_RS06220	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FIU99_RS06235	COG3152	Membrane
FIU99_RS06280	COG1858	cytochrome C peroxidase
FIU99_RS06295	COG0443	Heat shock 70 kDa protein
FIU99_RS06340	COG1643	Atp-dependent helicase
FIU99_RS06350	COG1301	dicarboxylic acid transport
FIU99_RS06355	COG0159	tryptophan synthase activity
FIU99_RS06365	COG0134	indole-3-glycerol-phosphate synthase activity
FIU99_RS06365	COG0135	phosphoribosylanthranilate isomerase activity
FIU99_RS06370	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FIU99_RS06375	COG0512	Glutamine amidotransferase of anthranilate synthase
FIU99_RS06380	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FIU99_RS06390	COG0613	PHP domain protein
FIU99_RS06395	COG0009	L-threonylcarbamoyladenylate synthase
FIU99_RS06410	COG1187	pseudouridine synthase activity
FIU99_RS06415	COG0384	phenazine biosynthesis protein PhzF
FIU99_RS06425	COG2814	Major facilitator Superfamily
FIU99_RS06430	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FIU99_RS06435	COG4988	ABC transporter
FIU99_RS06440	COG0492	ferredoxin-NADP+ reductase activity
FIU99_RS06455	COG2175	clavaminate synthase activity
FIU99_RS06470	COG0612	Peptidase, M16
FIU99_RS06480	COG2949	membrane
FIU99_RS06490	COG0281	malic enzyme
FIU99_RS06495	COG1643	Atp-dependent helicase
FIU99_RS06510	COG1448	Aminotransferase
FIU99_RS06515	COG2770	Histidine kinase
FIU99_RS06515	COG3437	response regulator, receiver
FIU99_RS06525	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FIU99_RS06540	COG0017	Asparaginyl-tRNA synthetase
FIU99_RS06555	COG0814	amino acid
FIU99_RS06565	COG1760	l-serine dehydratase
FIU99_RS06570	COG0814	amino acid
FIU99_RS06575	COG0494	nUDIX hydrolase
FIU99_RS06585	COG2205	protein histidine kinase activity
FIU99_RS06585	COG0784	Response regulator, receiver
FIU99_RS06605	COG3106	COG3106 Predicted ATPase
FIU99_RS06620	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FIU99_RS06640	COG3706	GGDEF domain
FIU99_RS06645	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FIU99_RS06670	COG2989	Protein conserved in bacteria
FIU99_RS06675	COG3108	Peptidase M15
FIU99_RS06680	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FIU99_RS06695	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FIU99_RS06730	COG4667	esterase of the alpha-beta hydrolase superfamily
FIU99_RS06735	COG0783	Belongs to the Dps family
FIU99_RS06745	COG0531	amino acid
FIU99_RS06750	COG2962	Rard protein
FIU99_RS06825	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FIU99_RS06965	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FIU99_RS07010	COG0546	phosphoglycolate phosphatase activity
FIU99_RS07015	COG4628	conserved protein (DUF2132)
FIU99_RS07025	COG0456	acetyltransferase
FIU99_RS07035	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FIU99_RS07045	COG0730	response to heat
FIU99_RS07055	COG1028	Short-chain dehydrogenase reductase Sdr
FIU99_RS07065	COG2824	Alkylphosphonate utilization operon protein PhnA
FIU99_RS07080	COG0456	acetyltransferase
FIU99_RS07105	COG3040	lipid binding
FIU99_RS07120	COG3122	Protein conserved in bacteria
FIU99_RS07175	COG0454	-acetyltransferase
FIU99_RS07180	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FIU99_RS07205	COG0456	acetyltransferase
FIU99_RS07225	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FIU99_RS07240	COG2195	Cleaves the N-terminal amino acid of tripeptides
FIU99_RS07250	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
FIU99_RS07260	COG0625	glutathione transferase activity
FIU99_RS07275	COG2885	chlorophyll binding
FIU99_RS07290	COG0247	lactate metabolic process
FIU99_RS07290	COG0277	FAD linked oxidase domain protein
FIU99_RS07305	COG2986	histidine ammonia-lyase
FIU99_RS07315	COG0010	Belongs to the arginase family
FIU99_RS07320	COG1228	amidohydrolase
FIU99_RS07325	COG2188	Transcriptional regulator
FIU99_RS07330	COG4326	sporulation control protein
FIU99_RS07350	COG0500	methyltransferase
FIU99_RS07355	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
FIU99_RS07365	COG0295	cytidine deaminase activity
FIU99_RS07370	COG1346	cytolysis
FIU99_RS07375	COG1380	Effector of murein hydrolase LrgA
FIU99_RS07380	COG2925	Exonuclease
FIU99_RS07385	COG1823	symporter activity
FIU99_RS07390	COG0702	epimerase
FIU99_RS07395	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FIU99_RS07400	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FIU99_RS07405	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FIU99_RS07415	COG0406	alpha-ribazole phosphatase activity
FIU99_RS07435	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
FIU99_RS07460	COG2814	Major facilitator Superfamily
FIU99_RS07470	COG1119	ATPase activity
FIU99_RS07480	COG0784	Response regulator, receiver
FIU99_RS07480	COG5002	protein histidine kinase activity
FIU99_RS07490	COG1451	nucleotide metabolic process
FIU99_RS07505	COG3063	Type IV pilus biogenesis stability protein PilW
FIU99_RS07510	COG0508	dehydrogenase complex catalyzes the overall conversion of
FIU99_RS07510	COG0596	Alpha beta hydrolase
FIU99_RS07515	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FIU99_RS07530	COG4943	cyclic-guanylate-specific phosphodiesterase activity
FIU99_RS07545	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FIU99_RS07570	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FIU99_RS07575	COG0515	serine threonine protein kinase
FIU99_RS07690	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FIU99_RS07695	COG0372	Belongs to the citrate synthase family
FIU99_RS07705	COG2828	Protein conserved in bacteria
FIU99_RS07725	COG0561	phosphatase activity
FIU99_RS07730	COG0602	queuosine metabolic process
FIU99_RS07760	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FIU99_RS07765	COG0840	transmembrane signaling receptor activity
FIU99_RS07770	COG1254	Belongs to the acylphosphatase family
FIU99_RS07775	COG2920	part of a sulfur-relay system
FIU99_RS07780	COG0670	Belongs to the BI1 family
FIU99_RS07785	COG1126	abc transporter atp-binding protein
FIU99_RS07790	COG0765	amino acid transport
FIU99_RS07795	COG4597	amino acid ABC transporter
FIU99_RS07800	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FIU99_RS07815	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FIU99_RS07840	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
FIU99_RS07840	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FIU99_RS07845	COG3008	intermembrane lipid transfer
FIU99_RS07850	COG2995	paraquat-inducible protein a
FIU99_RS07855	COG1132	(ABC) transporter
FIU99_RS07860	COG1956	GAF domain-containing protein
FIU99_RS07865	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
FIU99_RS07880	COG0308	aminopeptidase N
FIU99_RS07895	COG0167	dihydroorotate dehydrogenase activity
FIU99_RS07905	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FIU99_RS07905	COG0116	Belongs to the methyltransferase superfamily
FIU99_RS07915	COG0488	(ABC) transporter
FIU99_RS07930	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FIU99_RS07935	COG1067	ATP-dependent peptidase activity
FIU99_RS07990	COG0789	Transcriptional regulator
FIU99_RS08020	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FIU99_RS08040	COG0840	transmembrane signaling receptor activity
FIU99_RS08190	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FIU99_RS08220	COG1132	(ABC) transporter
FIU99_RS08300	COG2197	response regulator
FIU99_RS08335	COG3278	Belongs to the heme-copper respiratory oxidase family
FIU99_RS08350	COG2010	Cytochrome c
FIU99_RS08360	COG2217	Heavy metal translocating P-type atpase
FIU99_RS08375	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FIU99_RS08380	COG0589	response to stress
FIU99_RS08405	COG3842	ATPase activity
FIU99_RS08415	COG1177	transmembrane transport
FIU99_RS08420	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FIU99_RS08425	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FIU99_RS08430	COG2199	diguanylate cyclase activity
FIU99_RS08435	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FIU99_RS08440	COG0004	ammonium transporteR
FIU99_RS08455	COG0437	4 iron, 4 sulfur cluster binding
FIU99_RS08460	COG0243	molybdopterin cofactor binding
FIU99_RS08460	COG3383	formate dehydrogenase (NAD+) activity
FIU99_RS08490	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FIU99_RS08500	COG3038	cytochrome b561
FIU99_RS08525	COG0583	DNA-binding transcription factor activity
FIU99_RS08535	COG0583	DNA-binding transcription factor activity
FIU99_RS08540	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FIU99_RS08560	COG0069	glutamate synthase activity
FIU99_RS08565	COG1028	Short-chain dehydrogenase reductase Sdr
FIU99_RS08580	COG0488	(ABC) transporter
FIU99_RS08590	COG1595	DNA-templated transcription, initiation
FIU99_RS08605	COG3852	Histidine kinase
FIU99_RS08620	COG4662	Binding-protein-dependent transport system inner membrane component
FIU99_RS08625	COG3842	ATPase activity
FIU99_RS08630	COG0746	molybdenum cofactor guanylyltransferase activity
FIU99_RS08635	COG0303	'Molybdopterin
FIU99_RS08665	COG1940	carbohydrate kinase activity
FIU99_RS08670	COG3148	PFAM DTW domain containing protein
FIU99_RS08680	COG0840	transmembrane signaling receptor activity
FIU99_RS08685	COG0791	NLP P60 protein
FIU99_RS08695	COG3001	Fructosamine kinase
FIU99_RS08705	COG0307	riboflavin synthase, alpha
FIU99_RS08710	COG0534	Mate efflux family protein
FIU99_RS08755	COG2204	response regulator
FIU99_RS08765	COG0438	transferase activity, transferring glycosyl groups
FIU99_RS08800	COG0297	glycogen (starch) synthase activity
FIU99_RS08810	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FIU99_RS08845	COG4774	siderophore transport
FIU99_RS08865	COG4615	Cyclic peptide transporter
FIU99_RS08875	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FIU99_RS08880	COG1120	ATPase activity
FIU99_RS08885	COG2977	Belongs to the P-Pant transferase superfamily
FIU99_RS08890	COG1929	Belongs to the glycerate kinase type-1 family
FIU99_RS08895	COG3835	regulator
FIU99_RS08905	COG2814	Major facilitator Superfamily
FIU99_RS08915	COG1288	antiporter activity
FIU99_RS08925	COG2186	Transcriptional regulator
FIU99_RS08935	COG3713	MltA-interacting MipA family protein
FIU99_RS08945	COG0745	RESPONSE REGULATOR receiver
FIU99_RS08955	COG0583	DNA-binding transcription factor activity
FIU99_RS08975	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FIU99_RS08995	COG2116	formate transmembrane transporter activity
FIU99_RS09005	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FIU99_RS09015	COG2199	diguanylate cyclase activity
FIU99_RS09035	COG4565	transcriptional regulatory protein
FIU99_RS09040	COG3290	protein histidine kinase activity
FIU99_RS09060	COG0848	biopolymer transport protein
FIU99_RS09065	COG0811	peptide transport
FIU99_RS09070	COG0811	peptide transport
FIU99_RS09080	COG4774	siderophore transport
FIU99_RS09085	COG2205	protein histidine kinase activity
FIU99_RS09090	COG0745	RESPONSE REGULATOR receiver
FIU99_RS09095	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FIU99_RS09135	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FIU99_RS09140	COG1328	CTP reductase activity
FIU99_RS09145	COG0840	transmembrane signaling receptor activity
FIU99_RS09155	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FIU99_RS09165	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FIU99_RS09170	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FIU99_RS09175	COG0633	Ferredoxin
FIU99_RS09200	COG0019	diaminopimelate decarboxylase activity
FIU99_RS09245	COG0577	efflux transmembrane transporter activity
FIU99_RS09250	COG1136	(ABC) transporter
FIU99_RS09255	COG0534	Mate efflux family protein
FIU99_RS09260	COG0702	epimerase
FIU99_RS09270	COG2814	Major facilitator Superfamily
FIU99_RS09280	COG1061	Type III restriction enzyme res subunit
FIU99_RS09325	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FIU99_RS09330	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FIU99_RS09350	COG0463	Glycosyl transferase, family 2
FIU99_RS09375	COG0455	bacterial-type flagellum organization
FIU99_RS09395	COG2188	Transcriptional regulator
FIU99_RS09400	COG1263	PTS System
FIU99_RS09400	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FIU99_RS09405	COG1621	beta-fructofuranosidase activity
FIU99_RS09415	COG0583	DNA-binding transcription factor activity
FIU99_RS09420	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FIU99_RS09455	COG4221	oxidoreductase activity
FIU99_RS09485	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FIU99_RS09490	COG0307	riboflavin synthase, alpha
FIU99_RS09540	COG0242	peptide deformylase activity
FIU99_RS09545	COG0519	Catalyzes the synthesis of GMP from XMP
FIU99_RS09560	COG4580	involved in the transport of maltose and maltodextrins
FIU99_RS09565	COG0778	Nitroreductase
FIU99_RS09620	COG5001	Diguanylate cyclase
FIU99_RS09620	COG3300	MHYT domain
FIU99_RS09645	COG1115	amino acid carrier protein
FIU99_RS09650	COG1280	lysine exporter protein (LysE YggA)
FIU99_RS09655	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
FIU99_RS09660	COG0352	thiamine-phosphate diphosphorylase activity
FIU99_RS09665	COG0583	DNA-binding transcription factor activity
FIU99_RS09695	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FIU99_RS09705	COG1012	belongs to the aldehyde dehydrogenase family
FIU99_RS09715	COG0583	DNA-binding transcription factor activity
FIU99_RS09755	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FIU99_RS09765	COG1609	Transcriptional regulator
FIU99_RS09780	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FIU99_RS09785	COG1609	Transcriptional regulator
FIU99_RS09795	COG0642	Histidine kinase
FIU99_RS09800	COG0745	RESPONSE REGULATOR receiver
FIU99_RS09820	COG1858	cytochrome C peroxidase
FIU99_RS09830	COG2205	protein histidine kinase activity
FIU99_RS09830	COG0784	Response regulator, receiver
FIU99_RS09835	COG0488	(ABC) transporter
FIU99_RS09840	COG3437	response regulator, receiver
FIU99_RS09850	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FIU99_RS09860	COG2223	nitrite transmembrane transporter activity
FIU99_RS09865	COG1216	Glycosyl transferase, family 2
FIU99_RS09875	COG0673	inositol 2-dehydrogenase activity
FIU99_RS09880	COG3718	enzyme involved in inositol metabolism
FIU99_RS09905	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FIU99_RS09910	COG0673	inositol 2-dehydrogenase activity
FIU99_RS09915	COG3962	Belongs to the TPP enzyme family
FIU99_RS09925	COG0477	Major facilitator Superfamily
FIU99_RS09925	COG2814	Major facilitator Superfamily
FIU99_RS09945	COG0183	Belongs to the thiolase family
FIU99_RS09950	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FIU99_RS09990	COG3962	Belongs to the TPP enzyme family
FIU99_RS09995	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FIU99_RS10005	COG1129	ABC transporter
FIU99_RS10010	COG4211	Belongs to the binding-protein-dependent transport system permease family
FIU99_RS10020	COG0277	FAD linked oxidase domain protein
FIU99_RS10030	COG0583	DNA-binding transcription factor activity
FIU99_RS10050	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FIU99_RS10055	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FIU99_RS10075	COG1621	beta-fructofuranosidase activity
FIU99_RS10090	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FIU99_RS10090	COG1263	PTS System
FIU99_RS10100	COG1335	isochorismatase
FIU99_RS10105	COG1741	Belongs to the pirin family
FIU99_RS10150	COG4974	Belongs to the 'phage' integrase family
FIU99_RS10160	COG1733	regulation of RNA biosynthetic process
FIU99_RS10170	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FIU99_RS10190	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FIU99_RS10195	COG0072	phenylalanine-tRNA ligase activity
FIU99_RS10195	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FIU99_RS10205	COG3706	GGDEF domain
FIU99_RS10230	COG2133	pyrroloquinoline quinone binding
FIU99_RS10240	COG1902	pentaerythritol trinitrate reductase activity
FIU99_RS10270	COG0322	excinuclease ABC activity
FIU99_RS10275	COG2197	response regulator
FIU99_RS10290	COG0417	DNA replication proofreading
FIU99_RS10305	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FIU99_RS10315	COG0776	regulation of translation
FIU99_RS10350	COG2350	Protein conserved in bacteria
FIU99_RS10365	COG3313	Fe-S protein
FIU99_RS10375	COG4134	Bacterial extracellular solute-binding protein
FIU99_RS10380	COG4135	transport system, permease component
FIU99_RS10385	COG4136	ATPase activity
FIU99_RS10390	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FIU99_RS10395	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FIU99_RS10400	COG0564	pseudouridine synthase activity
FIU99_RS10405	COG0733	neurotransmitter:sodium symporter activity
FIU99_RS10415	COG0626	cystathionine gamma-synthase activity
FIU99_RS10420	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
FIU99_RS10425	COG5380	lipid catabolic process
FIU99_RS10430	COG2818	Glycosylase
FIU99_RS10445	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FIU99_RS10450	COG1983	PspC domain protein
FIU99_RS10460	COG1842	Phage shock protein A
FIU99_RS10465	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
FIU99_RS10480	COG4171	peptide transport system, permease
FIU99_RS10490	COG4172	Belongs to the ABC transporter superfamily
FIU99_RS10505	COG1227	inorganic diphosphatase activity
FIU99_RS10515	COG0217	transcriptional regulatory protein
FIU99_RS10520	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FIU99_RS10520	COG0140	phosphoribosyl-ATP diphosphatase activity
FIU99_RS10530	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FIU99_RS10535	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FIU99_RS10540	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FIU99_RS10540	COG0131	Imidazoleglycerol-phosphate dehydratase
FIU99_RS10550	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FIU99_RS10560	COG1757	Na H antiporter
FIU99_RS10570	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FIU99_RS10580	COG0482	sulfurtransferase activity
FIU99_RS10590	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FIU99_RS10600	COG2268	Band 7 protein
FIU99_RS10610	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FIU99_RS10625	COG1028	Short-chain dehydrogenase reductase Sdr
FIU99_RS10635	COG0501	Belongs to the peptidase M48B family
FIU99_RS10640	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FIU99_RS10645	COG1073	alpha beta
FIU99_RS10645	COG2226	methyltransferase
FIU99_RS10650	COG0156	8-amino-7-oxononanoate synthase activity
FIU99_RS10660	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FIU99_RS10675	COG1199	ATP-dependent helicase activity
FIU99_RS10680	COG0730	response to heat
FIU99_RS10695	COG2850	peptidyl-arginine hydroxylation
FIU99_RS10700	COG0840	transmembrane signaling receptor activity
FIU99_RS10705	COG0708	Exodeoxyribonuclease III
FIU99_RS10710	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FIU99_RS10715	COG1960	acyl-CoA dehydrogenase activity
FIU99_RS10730	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FIU99_RS10735	COG0463	Glycosyl transferase, family 2
FIU99_RS10740	COG0745	RESPONSE REGULATOR receiver
FIU99_RS10745	COG5002	protein histidine kinase activity
FIU99_RS10745	COG3850	Histidine kinase
FIU99_RS10760	COG1940	carbohydrate kinase activity
FIU99_RS10775	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FIU99_RS10780	COG1881	PFAM PEBP family protein
FIU99_RS10785	COG1902	pentaerythritol trinitrate reductase activity
FIU99_RS10805	COG0784	Response regulator, receiver
FIU99_RS10805	COG5002	protein histidine kinase activity
FIU99_RS10820	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FIU99_RS10825	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FIU99_RS10830	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
FIU99_RS10835	COG2885	chlorophyll binding
FIU99_RS10840	COG0823	Involved in the tonB-independent uptake of proteins
FIU99_RS10855	COG0811	peptide transport
FIU99_RS10860	COG0824	Thioesterase
FIU99_RS10870	COG4890	Cyd operon protein YbgT
FIU99_RS10875	COG1294	oxidase, subunit
FIU99_RS10880	COG1271	oxidase subunit
FIU99_RS10885	COG2255	four-way junction helicase activity
FIU99_RS10890	COG0632	four-way junction helicase activity
FIU99_RS10895	COG0840	transmembrane signaling receptor activity
FIU99_RS10900	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FIU99_RS10920	COG4221	oxidoreductase activity
FIU99_RS10935	COG0243	molybdopterin cofactor binding
FIU99_RS10940	COG3005	denitrification pathway
FIU99_RS10945	COG4459	periplasmic nitrate reductase
FIU99_RS10950	COG0390	transport system, permease component
FIU99_RS10955	COG2116	formate transmembrane transporter activity
FIU99_RS10980	COG0542	response to heat
FIU99_RS10985	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FIU99_RS10990	COG1278	Cold shock
FIU99_RS11000	COG1187	pseudouridine synthase activity
FIU99_RS11010	COG1801	Protein of unknown function DUF72
FIU99_RS11020	COG0500	methyltransferase
FIU99_RS11025	COG4067	protein conserved in archaea
FIU99_RS11025	COG0189	ligase activity
FIU99_RS11055	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FIU99_RS11060	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
FIU99_RS11070	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FIU99_RS11075	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FIU99_RS11080	COG0745	RESPONSE REGULATOR receiver
FIU99_RS11095	COG3070	regulator of competence-specific genes
FIU99_RS11115	COG0297	glycogen (starch) synthase activity
FIU99_RS11120	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FIU99_RS11125	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FIU99_RS11135	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FIU99_RS11145	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FIU99_RS11150	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FIU99_RS11155	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FIU99_RS11160	COG1435	thymidine kinase activity
FIU99_RS11165	COG0215	cysteine-tRNA ligase activity
FIU99_RS11170	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FIU99_RS11175	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FIU99_RS11180	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FIU99_RS11185	COG3012	SEC-C Motif Domain Protein
FIU99_RS11190	COG3139	Protein of unknown function (DUF1315)
FIU99_RS11200	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FIU99_RS11215	COG0840	transmembrane signaling receptor activity
FIU99_RS11220	COG2226	methyltransferase
FIU99_RS11235	COG1785	Belongs to the alkaline phosphatase family
FIU99_RS11255	COG0668	transmembrane transport
FIU99_RS11260	COG2983	Belongs to the UPF0260 family
FIU99_RS11275	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FIU99_RS11280	COG0583	DNA-binding transcription factor activity
FIU99_RS11285	COG2951	lytic endotransglycosylase activity
FIU99_RS11290	COG3100	YcgL domain-containing protein
FIU99_RS11295	COG0850	regulation of cytokinetic process
FIU99_RS11300	COG2894	cell division
FIU99_RS11305	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FIU99_RS11310	COG1454	alcohol dehydrogenase
FIU99_RS11310	COG1012	belongs to the aldehyde dehydrogenase family
FIU99_RS11315	COG2095	MarC family integral membrane protein
FIU99_RS11320	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FIU99_RS11325	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FIU99_RS11330	COG1757	Na H antiporter
FIU99_RS11350	COG3081	Nucleoid-associated protein
FIU99_RS11355	COG3082	Protein of unknown function (DUF1414)
FIU99_RS11360	COG3083	sulfuric ester hydrolase activity
FIU99_RS11425	COG0123	including yeast histone deacetylase and acetoin utilization protein
FIU99_RS11435	COG1881	PFAM PEBP family protein
FIU99_RS11445	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FIU99_RS11450	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FIU99_RS11470	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FIU99_RS11475	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FIU99_RS11475	COG0302	gtp cyclohydrolase
FIU99_RS11480	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FIU99_RS11485	COG0302	gtp cyclohydrolase
FIU99_RS11495	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
FIU99_RS11500	COG0110	maltose O-acetyltransferase activity
FIU99_RS11555	COG2982	Protein involved in outer membrane biogenesis
FIU99_RS11560	COG0572	uridine kinase
FIU99_RS11565	COG0489	protein tyrosine kinase activity
FIU99_RS11610	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FIU99_RS11610	COG0617	tRNA 3'-terminal CCA addition
FIU99_RS11610	COG0517	IMP dehydrogenase activity
FIU99_RS11620	COG3706	GGDEF domain
FIU99_RS11625	COG0314	molybdopterin synthase activity
FIU99_RS11630	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FIU99_RS11640	COG0521	Mo-molybdopterin cofactor biosynthetic process
FIU99_RS11645	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FIU99_RS11650	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FIU99_RS11655	COG2198	Histidine kinase
FIU99_RS11665	COG0556	nucleotide-excision repair
FIU99_RS11685	COG0739	heme binding
FIU99_RS11730	COG2885	chlorophyll binding
FIU99_RS11750	COG1987	bacterial-type flagellum assembly
FIU99_RS11775	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FIU99_RS11780	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FIU99_RS11785	COG1516	flagellar protein fliS
FIU99_RS11800	COG1580	Controls the rotational direction of flagella during chemotaxis
FIU99_RS11805	COG1191	sigma factor activity
FIU99_RS11810	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FIU99_RS11815	COG1360	Flagellar Motor Protein
FIU99_RS11845	COG1706	bacterial-type flagellum-dependent cell motility
FIU99_RS11850	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FIU99_RS11855	COG4786	Flagellar basal body rod
FIU99_RS11860	COG4787	bacterial-type flagellum-dependent cell motility
FIU99_RS11865	COG1749	Flagellar hook protein flgE
FIU99_RS11875	COG1558	bacterial-type flagellum-dependent cell motility
FIU99_RS11880	COG1815	bacterial-type flagellum-dependent cell motility
FIU99_RS11900	COG0741	lytic transglycosylase activity
FIU99_RS11900	COG1388	LysM domain
FIU99_RS11905	COG4657	Part of a membrane complex involved in electron transport
FIU99_RS11915	COG4656	Part of a membrane complex involved in electron transport
FIU99_RS11920	COG4658	electron transport chain
FIU99_RS11925	COG4659	FMN binding
FIU99_RS11930	COG4660	Part of a membrane complex involved in electron transport
FIU99_RS11935	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FIU99_RS11940	COG0346	lactoylglutathione lyase activity
FIU99_RS11960	COG2056	Na+-H+ antiporter family
FIU99_RS11965	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
FIU99_RS11975	COG2716	regulation of RNA biosynthetic process
FIU99_RS11980	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FIU99_RS12000	COG4783	chaperone-mediated protein folding
FIU99_RS12005	COG1393	Belongs to the ArsC family
FIU99_RS12030	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FIU99_RS12040	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FIU99_RS12045	COG2912	Transglutaminase-like superfamily
FIU99_RS12055	COG2890	protein-(glutamine-N5) methyltransferase activity
FIU99_RS12075	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FIU99_RS12080	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FIU99_RS12090	COG0012	GTP binding
FIU99_RS12210	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FIU99_RS12220	COG1705	Flagellar rod assembly protein muramidase FlgJ
FIU99_RS12220	COG3951	Flagellar rod assembly protein muramidase FlgJ
FIU99_RS12225	COG1706	bacterial-type flagellum-dependent cell motility
FIU99_RS12230	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FIU99_RS12240	COG4787	bacterial-type flagellum-dependent cell motility
FIU99_RS12260	COG1815	bacterial-type flagellum-dependent cell motility
FIU99_RS12265	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FIU99_RS12270	COG0784	Response regulator, receiver
FIU99_RS12270	COG0835	chemotaxis
FIU99_RS12280	COG2747	anti-sigma28 factor FlgM
FIU99_RS12320	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FIU99_RS12330	COG2194	sulfuric ester hydrolase activity
FIU99_RS12350	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FIU99_RS12350	COG2885	chlorophyll binding
FIU99_RS12370	COG2217	Heavy metal translocating P-type atpase
FIU99_RS12370	COG2608	mercury ion transmembrane transporter activity
FIU99_RS12390	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FIU99_RS12400	COG0326	Molecular chaperone. Has ATPase activity
FIU99_RS12405	COG3710	Transcriptional regulator
FIU99_RS12425	COG0622	Phosphoesterase
FIU99_RS12450	COG1090	epimerase
FIU99_RS12455	COG0300	oxidoreductase activity
FIU99_RS12465	COG3118	belongs to the thioredoxin family
FIU99_RS12470	COG0330	HflC and HflK could
FIU99_RS12490	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FIU99_RS12495	COG3115	cell septum assembly
FIU99_RS12500	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
FIU99_RS12505	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FIU99_RS12510	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FIU99_RS12515	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FIU99_RS12520	COG2190	(PTS) system
FIU99_RS12525	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FIU99_RS12535	COG1702	phosphate starvation-inducible protein PhoH
FIU99_RS12540	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FIU99_RS12545	COG4535	Mg2 and Co2 transporter CorC
FIU99_RS12550	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FIU99_RS12555	COG2888	peptidyl-tyrosine sulfation
FIU99_RS12560	COG0495	leucyl-tRNA aminoacylation
FIU99_RS12565	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
FIU99_RS12570	COG1466	dna polymerase III delta subunit
FIU99_RS12575	COG0799	negative regulation of ribosome biogenesis
FIU99_RS12580	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FIU99_RS12585	COG0768	penicillin binding
FIU99_RS12590	COG0772	Belongs to the SEDS family
FIU99_RS12595	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FIU99_RS12600	COG1686	Belongs to the peptidase S11 family
FIU99_RS12605	COG2921	Belongs to the UPF0250 family
FIU99_RS12615	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FIU99_RS12630	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FIU99_RS12640	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FIU99_RS12645	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FIU99_RS12670	COG0366	Alpha amylase catalytic
FIU99_RS12675	COG1263	PTS System
FIU99_RS12675	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FIU99_RS12680	COG1609	Transcriptional regulator
FIU99_RS12690	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FIU99_RS12695	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FIU99_RS12700	COG2011	ABC-type metal ion transport system permease component
FIU99_RS12705	COG1464	Belongs to the NlpA lipoprotein family
FIU99_RS12715	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
FIU99_RS12725	COG0254	rRNA binding
FIU99_RS12730	COG1720	tRNA m6t6A37 methyltransferase activity
FIU99_RS12740	COG0121	glutamine amidotransferase
FIU99_RS12745	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FIU99_RS12750	COG1960	acyl-CoA dehydrogenase activity
FIU99_RS12765	COG0328	RNA-DNA hybrid ribonuclease activity
FIU99_RS12770	COG2226	methyltransferase
FIU99_RS12775	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FIU99_RS12780	COG0741	lytic transglycosylase activity
FIU99_RS12780	COG1388	LysM domain
FIU99_RS12790	COG3021	interspecies interaction between organisms
FIU99_RS12795	COG0347	Belongs to the P(II) protein family
FIU99_RS12810	COG0825	malonyl-CoA metabolic process
FIU99_RS12815	COG0587	DNA-directed DNA polymerase activity
FIU99_RS12820	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FIU99_RS12835	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FIU99_RS12840	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FIU99_RS12845	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
FIU99_RS12850	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FIU99_RS12855	COG0750	zinc metalloprotease
FIU99_RS12865	COG0575	Belongs to the CDS family
FIU99_RS12870	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FIU99_RS12875	COG0233	cytoplasmic translational termination
FIU99_RS12880	COG0528	UMP kinase activity
FIU99_RS12885	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FIU99_RS12890	COG0052	Belongs to the universal ribosomal protein uS2 family
FIU99_RS12910	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FIU99_RS12915	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FIU99_RS12920	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FIU99_RS12940	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FIU99_RS12940	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FIU99_RS12945	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FIU99_RS12950	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FIU99_RS12955	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FIU99_RS12965	COG1073	alpha beta
FIU99_RS12970	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
FIU99_RS12975	COG2252	PERMEase
FIU99_RS12980	COG2195	Cleaves the N-terminal amino acid of tripeptides
FIU99_RS12985	COG0189	ligase activity
FIU99_RS12985	COG4067	protein conserved in archaea
FIU99_RS12990	COG0189	ligase activity
FIU99_RS13000	COG0733	neurotransmitter:sodium symporter activity
FIU99_RS13015	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FIU99_RS13025	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FIU99_RS13040	COG1477	protein flavinylation
FIU99_RS13045	COG2871	sodium ion transport
FIU99_RS13050	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FIU99_RS13065	COG1805	sodium ion transport
FIU99_RS13070	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FIU99_RS13075	COG0271	Belongs to the BolA IbaG family
FIU99_RS13080	COG2813	Specifically methylates the guanine in position
FIU99_RS13090	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FIU99_RS13105	COG1595	DNA-templated transcription, initiation
FIU99_RS13120	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FIU99_RS13125	COG0693	protein deglycase activity
FIU99_RS13130	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FIU99_RS13135	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FIU99_RS13145	COG0560	Phosphoserine phosphatase
FIU99_RS13155	COG0813	purine-nucleoside phosphorylase activity
FIU99_RS13160	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FIU99_RS13165	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FIU99_RS13180	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FIU99_RS13185	COG0084	hydrolase, TatD family'
FIU99_RS13190	COG3022	response to hydroperoxide
FIU99_RS13195	COG1115	amino acid carrier protein
FIU99_RS13225	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FIU99_RS13255	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FIU99_RS13260	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
FIU99_RS13265	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
FIU99_RS13270	COG0583	DNA-binding transcription factor activity
FIU99_RS13275	COG0730	response to heat
FIU99_RS13280	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FIU99_RS13285	COG0505	Belongs to the CarA family
FIU99_RS13295	COG0494	nUDIX hydrolase
FIU99_RS13300	COG0653	protein targeting
FIU99_RS13305	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
FIU99_RS13310	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FIU99_RS13315	COG0849	cell division
FIU99_RS13320	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FIU99_RS13335	COG0772	Belongs to the SEDS family
FIU99_RS13340	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FIU99_RS13350	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FIU99_RS13360	COG0768	penicillin binding
FIU99_RS13365	COG3116	cell division
FIU99_RS13380	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FIU99_RS13385	COG3107	peptidoglycan biosynthetic process
FIU99_RS13395	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FIU99_RS13405	COG2969	positive regulation of protein catabolic process
FIU99_RS13410	COG0625	glutathione transferase activity
FIU99_RS13415	COG2857	Cytochrome c1
FIU99_RS13420	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FIU99_RS13425	COG0723	plastoquinol--plastocyanin reductase activity
FIU99_RS13440	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FIU99_RS13445	COG3105	Protein conserved in bacteria
FIU99_RS13450	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FIU99_RS13455	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FIU99_RS13470	COG3150	esterase
FIU99_RS13480	COG3151	Protein conserved in bacteria
FIU99_RS13485	COG0494	nUDIX hydrolase
FIU99_RS13490	COG1538	Outer membrane efflux protein
FIU99_RS13500	COG0784	Response regulator, receiver
FIU99_RS13500	COG5002	protein histidine kinase activity
FIU99_RS13500	COG2198	Histidine kinase
FIU99_RS13505	COG4251	negative regulation of phosphorylation
FIU99_RS13505	COG5001	Diguanylate cyclase
FIU99_RS13505	COG2203	Gaf domain
FIU99_RS13505	COG3706	GGDEF domain
FIU99_RS13510	COG1242	4 iron, 4 sulfur cluster binding
FIU99_RS13515	COG0070	glutamate synthase
FIU99_RS13515	COG0069	glutamate synthase activity
FIU99_RS13515	COG0067	glutamate synthase
FIU99_RS13525	COG0070	glutamate synthase
FIU99_RS13525	COG0067	glutamate synthase
FIU99_RS13525	COG0069	glutamate synthase activity
FIU99_RS13530	COG0493	'glutamate synthase
FIU99_RS13555	COG0195	Participates in both transcription termination and antitermination
FIU99_RS13560	COG0779	Required for maturation of 30S ribosomal subunits
FIU99_RS13575	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FIU99_RS13580	COG3153	acetyltransferase
FIU99_RS13585	COG3154	lipid carrier protein
FIU99_RS13595	COG0826	peptidase U32
FIU99_RS13600	COG0826	peptidase U32
FIU99_RS13605	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FIU99_RS13625	COG0513	Belongs to the DEAD box helicase family
FIU99_RS13655	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FIU99_RS13660	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FIU99_RS13665	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FIU99_RS13670	COG1534	Rna-binding protein
FIU99_RS13675	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FIU99_RS13680	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FIU99_RS13685	COG2027	D-alanyl-D-alanine carboxypeptidase
FIU99_RS13695	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FIU99_RS13700	COG0739	heme binding
FIU99_RS13715	COG0316	Belongs to the HesB IscA family
FIU99_RS13725	COG0628	permease
FIU99_RS13730	COG2813	Specifically methylates the guanine in position
FIU99_RS13735	COG0784	Response regulator, receiver
FIU99_RS13735	COG2205	protein histidine kinase activity
FIU99_RS13740	COG0747	negative chemotaxis
FIU99_RS13755	COG0444	Belongs to the ABC transporter superfamily
FIU99_RS13760	COG4608	Belongs to the ABC transporter superfamily
FIU99_RS13770	COG2971	BadF BadG BcrA BcrD
FIU99_RS13785	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FIU99_RS13790	COG3842	ATPase activity
FIU99_RS13800	COG1840	ABC-type Fe3 transport system, periplasmic component
FIU99_RS13805	COG0004	ammonium transporteR
FIU99_RS13820	COG1049	propionate catabolic process, 2-methylcitrate cycle
FIU99_RS13825	COG1752	Esterase of the alpha-beta hydrolase superfamily
FIU99_RS13830	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FIU99_RS13835	COG1643	Atp-dependent helicase
FIU99_RS13845	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FIU99_RS13860	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FIU99_RS13865	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FIU99_RS13875	COG0842	Transport permease protein
FIU99_RS13880	COG1131	(ABC) transporter
FIU99_RS13885	COG0659	secondary active sulfate transmembrane transporter activity
FIU99_RS13890	COG0288	reversible hydration of carbon dioxide
FIU99_RS13905	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FIU99_RS13910	COG0508	dehydrogenase complex catalyzes the overall conversion of
FIU99_RS13915	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FIU99_RS13920	COG2186	Transcriptional regulator
FIU99_RS13925	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FIU99_RS13930	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FIU99_RS13935	COG4974	Belongs to the 'phage' integrase family
FIU99_RS13945	COG3023	N-Acetylmuramoyl-L-alanine amidase
FIU99_RS13950	COG0157	Belongs to the NadC ModD family
FIU99_RS13955	COG4969	Belongs to the N-Me-Phe pilin family
FIU99_RS13960	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FIU99_RS13965	COG1459	type II secretion system
FIU99_RS13975	COG0237	dephospho-CoA kinase activity
FIU99_RS13980	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
FIU99_RS13985	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FIU99_RS13995	COG0336	Belongs to the RNA methyltransferase TrmD family
FIU99_RS14005	COG0228	four-way junction DNA binding
FIU99_RS14010	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FIU99_RS14015	COG4137	Cytochrome C assembly protein
FIU99_RS14020	COG4536	flavin adenine dinucleotide binding
FIU99_RS14025	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FIU99_RS14040	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FIU99_RS14045	COG0585	pseudouridine synthase activity
FIU99_RS14055	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FIU99_RS14060	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
FIU99_RS14065	COG1968	undecaprenyl-diphosphatase activity
FIU99_RS14070	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FIU99_RS14075	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FIU99_RS14080	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FIU99_RS14085	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FIU99_RS14090	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FIU99_RS14095	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FIU99_RS14100	COG1610	YqeY-like protein
FIU99_RS14105	COG0358	DNA primase activity
FIU99_RS14120	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FIU99_RS14125	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FIU99_RS14130	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FIU99_RS14135	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FIU99_RS14140	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FIU99_RS14150	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FIU99_RS14160	COG3610	response to peptide
FIU99_RS14165	COG2966	Psort location CytoplasmicMembrane, score
FIU99_RS14170	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FIU99_RS14180	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FIU99_RS14185	COG0142	geranyltranstransferase activity
FIU99_RS14195	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FIU99_RS14200	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FIU99_RS14200	COG2213	PTS system mannitol-specific
FIU99_RS14210	COG3722	fumarate hydratase activity
FIU99_RS14215	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FIU99_RS14220	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FIU99_RS14225	COG1349	DNA-binding transcription factor activity
FIU99_RS14230	COG0469	pyruvate kinase activity
FIU99_RS14250	COG0583	DNA-binding transcription factor activity
FIU99_RS14265	COG0668	transmembrane transport
FIU99_RS14270	COG0191	fructose-bisphosphate aldolase activity
FIU99_RS14280	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FIU99_RS14285	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FIU99_RS14290	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FIU99_RS14300	COG3091	SprT-like family
FIU99_RS14305	COG2356	endonuclease I
FIU99_RS14310	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FIU99_RS14315	COG0189	ligase activity
FIU99_RS14320	COG1678	Uncharacterized ACR, COG1678
FIU99_RS14325	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FIU99_RS14340	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FIU99_RS14345	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FIU99_RS14350	COG0762	integral membrane protein
FIU99_RS14475	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FIU99_RS14480	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FIU99_RS14485	COG2066	Belongs to the glutaminase family
FIU99_RS14490	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FIU99_RS14500	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
FIU99_RS14555	COG0312	modulator of DNA gyrase
FIU99_RS14560	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FIU99_RS14565	COG3164	Protein of unknown function
FIU99_RS14575	COG0424	maF-like protein
FIU99_RS14580	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FIU99_RS14585	COG1792	Involved in formation and maintenance of cell shape
FIU99_RS14590	COG1077	Cell shape determining protein MreB Mrl
FIU99_RS14620	COG2165	general secretion pathway protein
FIU99_RS14625	COG2165	general secretion pathway protein
FIU99_RS14635	COG1459	type II secretion system
FIU99_RS14640	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FIU99_RS14650	COG3267	Type II secretory pathway component ExeA
FIU99_RS14650	COG3409	Peptidoglycan-binding domain 1 protein
FIU99_RS14675	COG2200	EAL domain
FIU99_RS14675	COG2199	diguanylate cyclase activity
FIU99_RS14680	COG0629	single-stranded DNA binding
FIU99_RS14695	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FIU99_RS14705	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FIU99_RS14710	COG0527	aspartate kinase activity
FIU99_RS14715	COG0312	modulator of DNA gyrase
FIU99_RS14720	COG3028	Belongs to the UPF0307 family
FIU99_RS14725	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FIU99_RS14730	COG1178	ABC-type Fe3 transport system permease component
FIU99_RS14735	COG4143	(ABC) transporter
FIU99_RS14740	COG0163	prenyltransferase activity
FIU99_RS14745	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FIU99_RS14755	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FIU99_RS14760	COG2105	PFAM AIG2 family protein
FIU99_RS14765	COG2911	Protein conserved in bacteria
FIU99_RS14770	COG0729	surface antigen
FIU99_RS14775	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FIU99_RS14785	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
FIU99_RS14800	COG1136	(ABC) transporter
FIU99_RS14920	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FIU99_RS14925	COG0305	Participates in initiation and elongation during chromosome replication
FIU99_RS14945	COG0360	Binds together with S18 to 16S ribosomal RNA
FIU99_RS14955	COG2906	2 iron, 2 sulfur cluster binding
FIU99_RS14960	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FIU99_RS14965	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FIU99_RS14970	COG0049	tRNA binding
FIU99_RS14980	COG2168	tRNA wobble position uridine thiolation
FIU99_RS14985	COG2923	Belongs to the DsrF TusC family
FIU99_RS14990	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
FIU99_RS14995	COG2964	Protein conserved in bacteria
FIU99_RS15000	COG0545	Peptidyl-prolyl cis-trans isomerase
FIU99_RS15010	COG2900	Belongs to the SlyX family
FIU99_RS15015	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
FIU99_RS15020	COG0330	HflC and HflK could
FIU99_RS15025	COG0330	HflC and HflK could
FIU99_RS15030	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FIU99_RS15045	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FIU99_RS15055	COG0802	atpase or kinase
FIU99_RS15060	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FIU99_RS15115	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FIU99_RS15120	COG1162	GTPase activity
FIU99_RS15125	COG0688	phosphatidylethanolamine metabolic process
FIU99_RS15130	COG0471	metal ion transport
FIU99_RS15130	COG0490	domain, Protein
FIU99_RS15135	COG0840	transmembrane signaling receptor activity
FIU99_RS15145	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FIU99_RS15150	COG4942	peptidase
FIU99_RS15170	COG2816	NAD+ diphosphatase activity
FIU99_RS15175	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
FIU99_RS15185	COG0085	RNA polymerase activity
FIU99_RS15195	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FIU99_RS15210	COG0250	Participates in transcription elongation, termination and antitermination
FIU99_RS15215	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FIU99_RS15220	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FIU99_RS15245	COG1072	(Pantothenic acid kinase))
FIU99_RS15260	COG0149	triose-phosphate isomerase activity
FIU99_RS15265	COG0534	Mate efflux family protein
FIU99_RS15270	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FIU99_RS15275	COG1575	Belongs to the MenA family. Type 1 subfamily
FIU99_RS15280	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FIU99_RS15285	COG1509	lysine 2,3-aminomutase activity
FIU99_RS15295	COG1285	pathogenesis
FIU99_RS15300	COG0205	6-phosphofructokinase activity
FIU99_RS15310	COG3678	ATP-independent chaperone mediated protein folding
FIU99_RS15315	COG0745	RESPONSE REGULATOR receiver
FIU99_RS15320	COG2205	protein histidine kinase activity
FIU99_RS15325	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FIU99_RS15330	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FIU99_RS15335	COG0180	Tryptophanyl-tRNA synthetase
FIU99_RS15340	COG0546	phosphoglycolate phosphatase activity
FIU99_RS15345	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FIU99_RS15350	COG0338	D12 class N6 adenine-specific DNA methyltransferase
FIU99_RS15360	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FIU99_RS15395	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FIU99_RS15405	COG0678	peroxiredoxin activity
FIU99_RS15405	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FIU99_RS15415	COG0251	oxidation-reduction process
FIU99_RS15425	COG0165	Argininosuccinate lyase
FIU99_RS15425	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FIU99_RS15430	COG0137	argininosuccinate synthase activity
FIU99_RS15440	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FIU99_RS15445	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FIU99_RS15540	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FIU99_RS15550	COG4206	TonB-dependent receptor
FIU99_RS15570	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FIU99_RS15575	COG0534	Mate efflux family protein
FIU99_RS15585	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FIU99_RS15595	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FIU99_RS15600	COG2937	Belongs to the GPAT DAPAT family
FIU99_RS15605	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FIU99_RS15610	COG3161	chorismate lyase activity
FIU99_RS15615	COG1580	Controls the rotational direction of flagella during chemotaxis
FIU99_RS15625	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FIU99_RS15630	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FIU99_RS15635	COG2177	Part of the ABC transporter FtsEX involved in
FIU99_RS15640	COG2884	Cell division ATP-binding protein ftsE
FIU99_RS15645	COG0552	protein localization to endoplasmic reticulum
FIU99_RS15650	COG0742	ribosomal rna small subunit methyltransferase
FIU99_RS15660	COG2095	MarC family integral membrane protein
FIU99_RS15710	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FIU99_RS15715	COG0640	Transcriptional regulator
FIU99_RS15720	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FIU99_RS15725	COG1280	lysine exporter protein (LysE YggA)
FIU99_RS15735	COG0561	phosphatase activity
FIU99_RS15750	COG3148	PFAM DTW domain containing protein
FIU99_RS15755	COG2199	diguanylate cyclase activity
FIU99_RS15755	COG3287	FIST C domain
FIU99_RS15755	COG2200	EAL domain
FIU99_RS15760	COG1011	Hydrolase
FIU99_RS15765	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FIU99_RS15775	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FIU99_RS15780	COG0019	diaminopimelate decarboxylase activity
FIU99_RS15790	COG1965	Belongs to the frataxin family
FIU99_RS15795	COG3072	Adenylate cyclase
FIU99_RS15800	COG0181	hydroxymethylbilane synthase activity
FIU99_RS15805	COG1587	Uroporphyrinogen-III synthase
FIU99_RS15810	COG2959	enzyme of heme biosynthesis
FIU99_RS15815	COG3071	HemY protein
FIU99_RS15880	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FIU99_RS15895	COG3118	belongs to the thioredoxin family
FIU99_RS15905	COG0248	Ppx GppA phosphatase
FIU99_RS15910	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FIU99_RS15920	COG0514	ATP-dependent DNA helicase (RecQ)
FIU99_RS15925	COG2962	Rard protein
FIU99_RS15935	COG1280	lysine exporter protein (LysE YggA)
FIU99_RS15940	COG0405	Gamma-glutamyltransferase
FIU99_RS15960	COG0210	DNA helicase
FIU99_RS15970	COG3220	belongs to the UPF0276 family
FIU99_RS15990	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FIU99_RS15995	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FIU99_RS16010	COG1773	rubredoxin
FIU99_RS16025	COG0367	asparagine synthase
FIU99_RS16030	COG0477	Major facilitator Superfamily
FIU99_RS16050	COG0745	RESPONSE REGULATOR receiver
FIU99_RS16065	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FIU99_RS16070	COG0601	transmembrane transport
FIU99_RS16075	COG0747	negative chemotaxis
FIU99_RS16120	COG1309	transcriptional regulator
FIU99_RS16125	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FIU99_RS16130	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FIU99_RS16135	COG2960	long-chain fatty acid transporting porin activity
FIU99_RS16140	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FIU99_RS16145	COG0583	DNA-binding transcription factor activity
FIU99_RS16150	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FIU99_RS16180	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FIU99_RS16180	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FIU99_RS16205	COG0084	hydrolase, TatD family'
FIU99_RS16210	COG0805	protein transport
FIU99_RS16215	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FIU99_RS16220	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FIU99_RS16235	COG2226	methyltransferase
FIU99_RS16240	COG1322	Protein conserved in bacteria
FIU99_RS16250	COG1639	'signal transduction protein
FIU99_RS16280	COG2081	HI0933 family
FIU99_RS16290	COG1528	Iron-storage protein
FIU99_RS16295	COG0589	response to stress
FIU99_RS16310	COG0742	ribosomal rna small subunit methyltransferase
FIU99_RS16315	COG5001	Diguanylate cyclase
FIU99_RS16315	COG5002	protein histidine kinase activity
FIU99_RS16320	COG1522	sequence-specific DNA binding
FIU99_RS16345	COG0006	proline dipeptidase activity
FIU99_RS16345	COG0006	proline dipeptidase activity
FIU99_RS16355	COG2022	thiamine diphosphate biosynthetic process
FIU99_RS16365	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FIU99_RS16370	COG0352	thiamine-phosphate diphosphorylase activity
FIU99_RS16385	COG2132	Multicopper oxidase
FIU99_RS16445	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FIU99_RS16450	COG1739	Uncharacterized protein family UPF0029
FIU99_RS16460	COG0183	Belongs to the thiolase family
FIU99_RS16465	COG3706	GGDEF domain
FIU99_RS16470	COG0583	DNA-binding transcription factor activity
FIU99_RS16475	COG2814	Major facilitator Superfamily
FIU99_RS16485	COG0765	amino acid transport
FIU99_RS16495	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FIU99_RS16500	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FIU99_RS16505	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FIU99_RS16510	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FIU99_RS16515	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FIU99_RS16535	COG3312	ion transport
FIU99_RS16540	COG1475	DNA binding
FIU99_RS16545	COG1192	Involved in chromosome partitioning
FIU99_RS16550	COG0357	Ribosomal RNA small subunit methyltransferase G
FIU99_RS16555	COG0445	tRNA wobble uridine modification
FIU99_RS16560	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FIU99_RS16565	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FIU99_RS16570	COG0706	membrane insertase activity
FIU99_RS16585	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FIU99_RS16590	COG1126	abc transporter atp-binding protein
FIU99_RS16640	COG3501	Rhs element vgr protein
FIU99_RS16665	COG0515	serine threonine protein kinase
FIU99_RS16665	COG2815	serine threonine protein kinase
FIU99_RS16700	COG1522	sequence-specific DNA binding
FIU99_RS16740	COG3250	beta-galactosidase activity
FIU99_RS16745	COG2211	Major facilitator Superfamily
FIU99_RS16760	COG1609	Transcriptional regulator
FIU99_RS16765	COG1309	transcriptional regulator
FIU99_RS16770	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FIU99_RS16775	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FIU99_RS16790	COG0183	Belongs to the thiolase family
FIU99_RS16805	COG1794	racemase activity, acting on amino acids and derivatives
FIU99_RS16810	COG2814	Major facilitator Superfamily
FIU99_RS16815	COG3240	lipase activity
FIU99_RS16865	COG1328	CTP reductase activity
FIU99_RS16870	COG0602	queuosine metabolic process
FIU99_RS16880	COG4067	protein conserved in archaea
FIU99_RS16880	COG0189	ligase activity
FIU99_RS16890	COG0545	Peptidyl-prolyl cis-trans isomerase
FIU99_RS16910	COG0247	lactate metabolic process
FIU99_RS16915	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
FIU99_RS16920	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FIU99_RS16925	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FIU99_RS16930	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FIU99_RS16940	COG2926	Belongs to the UPF0265 family
FIU99_RS16950	COG3132	Protein of unknown function, DUF480
FIU99_RS16955	COG2827	Endonuclease containing a URI domain
FIU99_RS16970	COG0784	Response regulator, receiver
FIU99_RS16970	COG5002	protein histidine kinase activity
FIU99_RS16995	COG1289	transmembrane transporter activity
FIU99_RS17000	COG0210	DNA helicase
FIU99_RS17020	COG0484	heat shock protein binding
FIU99_RS17030	COG5001	Diguanylate cyclase
FIU99_RS17030	COG3300	MHYT domain
FIU99_RS17035	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FIU99_RS17045	COG4181	ATPase activity
FIU99_RS17050	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FIU99_RS17055	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
FIU99_RS17060	COG1984	allophanate hydrolase subunit 2
FIU99_RS17070	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FIU99_RS17075	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FIU99_RS17095	COG0243	molybdopterin cofactor binding
FIU99_RS17105	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FIU99_RS17110	COG3850	Histidine kinase
FIU99_RS17115	COG2197	response regulator
FIU99_RS17120	COG3069	C4-dicarboxylate transmembrane transporter activity
FIU99_RS17140	COG3038	cytochrome b561
FIU99_RS17145	COG2353	YceI-like domain
FIU99_RS17150	COG2116	formate transmembrane transporter activity
FIU99_RS17155	COG0583	DNA-binding transcription factor activity
FIU99_RS17165	COG3593	DNA synthesis involved in DNA repair
FIU99_RS17170	COG0737	Belongs to the 5'-nucleotidase family
FIU99_RS17200	COG1605	Chorismate mutase
FIU99_RS17215	COG0745	RESPONSE REGULATOR receiver
FIU99_RS17220	COG2205	protein histidine kinase activity
FIU99_RS17220	COG0784	Response regulator, receiver
FIU99_RS17225	COG0840	transmembrane signaling receptor activity
FIU99_RS17230	COG3070	regulator of competence-specific genes
FIU99_RS17235	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FIU99_RS17255	COG2050	protein possibly involved in aromatic compounds catabolism
FIU99_RS17275	COG1629	transport
FIU99_RS17275	COG4771	TonB-dependent receptor
FIU99_RS17280	COG0583	DNA-binding transcription factor activity
FIU99_RS17285	COG0045	succinate-CoA ligase (ADP-forming) activity
FIU99_RS17285	COG1042	CoA-binding domain protein
FIU99_RS17285	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FIU99_RS17290	COG3266	domain, Protein
FIU99_RS17295	COG1181	Belongs to the D-alanine--D-alanine ligase family
FIU99_RS17310	COG0023	Translation Initiation Factor
FIU99_RS17325	COG3140	Belongs to the UPF0181 family
FIU99_RS17340	COG0745	RESPONSE REGULATOR receiver
FIU99_RS17350	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FIU99_RS17355	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FIU99_RS17370	COG3706	GGDEF domain
FIU99_RS17375	COG2203	Gaf domain
FIU99_RS17375	COG4251	negative regulation of phosphorylation
FIU99_RS17375	COG5001	Diguanylate cyclase
FIU99_RS17375	COG3706	GGDEF domain
FIU99_RS17385	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FIU99_RS17390	COG4149	molybdate abc transporter
FIU99_RS17395	COG0725	ABC transporter, periplasmic molybdate-binding protein
FIU99_RS17415	COG1609	Transcriptional regulator
FIU99_RS17420	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FIU99_RS17420	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FIU99_RS17425	COG1105	Belongs to the carbohydrate kinase PfkB family
FIU99_RS17430	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FIU99_RS17430	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
FIU99_RS17430	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FIU99_RS17435	COG3706	GGDEF domain
FIU99_RS17440	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FIU99_RS17445	COG2207	Transcriptional regulator
FIU99_RS17450	COG1979	alcohol dehydrogenase
FIU99_RS17465	COG0784	Response regulator, receiver
FIU99_RS17465	COG2205	protein histidine kinase activity
FIU99_RS17465	COG2198	Histidine kinase
FIU99_RS17470	COG1879	ABC-type sugar transport system periplasmic component
FIU99_RS17475	COG1803	Methylglyoxal synthase
FIU99_RS17480	COG2188	Transcriptional regulator
FIU99_RS17490	COG1263	PTS System
FIU99_RS17490	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FIU99_RS17495	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FIU99_RS17500	COG0800	Aldolase
FIU99_RS17510	COG0546	phosphoglycolate phosphatase activity
FIU99_RS17525	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FIU99_RS17530	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FIU99_RS17540	COG0583	DNA-binding transcription factor activity
FIU99_RS17545	COG3048	D-serine ammonia-lyase activity
FIU99_RS17555	COG0346	lactoylglutathione lyase activity
FIU99_RS17570	COG0456	acetyltransferase
FIU99_RS17570	COG1214	PFAM Peptidase M22, glycoprotease
FIU99_RS17600	COG0513	Belongs to the DEAD box helicase family
FIU99_RS17610	COG0814	amino acid
FIU99_RS17615	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FIU99_RS17615	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FIU99_RS17625	COG0513	Belongs to the DEAD box helicase family
FIU99_RS17640	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FIU99_RS17655	COG2897	thiosulfate sulfurtransferase activity
FIU99_RS17680	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FIU99_RS17685	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FIU99_RS17690	COG1522	sequence-specific DNA binding
FIU99_RS17700	COG0006	proline dipeptidase activity
FIU99_RS17705	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FIU99_RS17710	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FIU99_RS17715	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FIU99_RS17720	COG1473	amidohydrolase
FIU99_RS17730	COG1522	sequence-specific DNA binding
FIU99_RS17765	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FIU99_RS17775	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FIU99_RS17780	COG0523	cobalamin synthesis protein
FIU99_RS17785	COG0038	chloride channel
FIU99_RS17795	COG0156	8-amino-7-oxononanoate synthase activity
FIU99_RS17800	COG0784	Response regulator, receiver
FIU99_RS17800	COG2205	protein histidine kinase activity
FIU99_RS17805	COG0419	ATPase involved in DNA repair
FIU99_RS17815	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FIU99_RS17820	COG3118	belongs to the thioredoxin family
FIU99_RS17845	COG2146	nitrite reductase [NAD(P)H] activity
FIU99_RS17850	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FIU99_RS17850	COG2146	nitrite reductase [NAD(P)H] activity
FIU99_RS17855	COG1116	anion transmembrane transporter activity
FIU99_RS17860	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FIU99_RS17865	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FIU99_RS17865	COG1116	anion transmembrane transporter activity
FIU99_RS17875	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FIU99_RS17880	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FIU99_RS17880	COG1648	precorrin-2 dehydrogenase activity
FIU99_RS17925	COG2315	Protein conserved in bacteria
FIU99_RS17935	COG2199	diguanylate cyclase activity
FIU99_RS17935	COG2203	Gaf domain
FIU99_RS17960	COG3706	GGDEF domain
FIU99_RS17980	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
FIU99_RS17985	COG1028	Short-chain dehydrogenase reductase Sdr
FIU99_RS17995	COG1024	Enoyl-CoA hydratase
FIU99_RS18000	COG1024	Enoyl-CoA hydratase
FIU99_RS18005	COG1960	acyl-CoA dehydrogenase activity
FIU99_RS18015	COG0183	Belongs to the thiolase family
FIU99_RS18025	COG1960	acyl-CoA dehydrogenase activity
FIU99_RS18030	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FIU99_RS18065	COG2259	Doxx family
FIU99_RS18070	COG1741	Belongs to the pirin family
FIU99_RS18085	COG1115	amino acid carrier protein
FIU99_RS18090	COG0583	DNA-binding transcription factor activity
FIU99_RS18095	COG2910	NAD(P)H-binding
FIU99_RS18115	COG1716	ATPase activity
FIU99_RS18115	COG5001	Diguanylate cyclase
FIU99_RS18140	COG1858	cytochrome C peroxidase
FIU99_RS18165	COG0583	DNA-binding transcription factor activity
FIU99_RS18170	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FIU99_RS18175	COG5001	Diguanylate cyclase
FIU99_RS18175	COG3300	MHYT domain
FIU99_RS18185	COG0789	Transcriptional regulator
FIU99_RS18195	COG2176	DNA-directed DNA polymerase activity
FIU99_RS18200	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FIU99_RS18205	COG1846	Transcriptional regulator
FIU99_RS18210	COG3706	GGDEF domain
FIU99_RS18235	COG2814	Major facilitator Superfamily
FIU99_RS18240	COG2425	protein containing a von Willebrand factor type A (vWA) domain
FIU99_RS18245	COG0714	Associated with various cellular activities
FIU99_RS18250	COG0494	nUDIX hydrolase
FIU99_RS18260	COG1028	Short-chain dehydrogenase reductase Sdr
FIU99_RS18275	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FIU99_RS18280	COG0835	chemotaxis
FIU99_RS18280	COG0784	Response regulator, receiver
FIU99_RS18285	COG3706	GGDEF domain
FIU99_RS18310	COG1760	l-serine dehydratase
FIU99_RS18315	COG0583	DNA-binding transcription factor activity
FIU99_RS18320	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FIU99_RS18325	COG2866	Carboxypeptidase
FIU99_RS18330	COG3104	oligopeptide transport
FIU99_RS18355	COG3842	ATPase activity
FIU99_RS18365	COG1840	ABC-type Fe3 transport system, periplasmic component
FIU99_RS18370	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FIU99_RS18375	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FIU99_RS18395	COG2378	regulation of single-species biofilm formation
FIU99_RS18405	COG1011	Hydrolase
FIU99_RS18415	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
FIU99_RS18420	COG1454	alcohol dehydrogenase
FIU99_RS18465	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FIU99_RS18470	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FIU99_RS18520	COG3186	Phenylalanine-4-hydroxylase
FIU99_RS18525	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FIU99_RS18530	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FIU99_RS18550	COG0784	Response regulator, receiver
FIU99_RS18550	COG2205	protein histidine kinase activity
FIU99_RS18555	COG2205	protein histidine kinase activity
FIU99_RS18555	COG0784	Response regulator, receiver
FIU99_RS18560	COG0612	Peptidase, M16
FIU99_RS18570	COG0798	PFAM Bile acid sodium symporter
FIU99_RS18590	COG2195	Cleaves the N-terminal amino acid of tripeptides
FIU99_RS18600	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FIU99_RS18630	COG1063	alcohol dehydrogenase
FIU99_RS18635	COG0156	8-amino-7-oxononanoate synthase activity
FIU99_RS18640	COG2200	EAL domain
FIU99_RS18640	COG2202	Pas domain
FIU99_RS18640	COG2199	diguanylate cyclase activity
FIU99_RS18660	COG0346	lactoylglutathione lyase activity
FIU99_RS18670	COG4452	Inner membrane protein CreD
FIU99_RS18675	COG2205	protein histidine kinase activity
FIU99_RS18680	COG0745	RESPONSE REGULATOR receiver
FIU99_RS18690	COG0745	RESPONSE REGULATOR receiver
FIU99_RS18695	COG2205	protein histidine kinase activity
FIU99_RS18710	COG0667	Aldo Keto reductase
FIU99_RS18715	COG0583	DNA-binding transcription factor activity
FIU99_RS18730	COG0714	Associated with various cellular activities
FIU99_RS18745	COG2304	oxidoreductase activity
FIU99_RS18750	COG2304	oxidoreductase activity
FIU99_RS18770	COG0110	maltose O-acetyltransferase activity
FIU99_RS18775	COG1765	OsmC-like protein
FIU99_RS18780	COG0673	inositol 2-dehydrogenase activity
FIU99_RS18800	COG0531	amino acid
FIU99_RS18825	COG0745	RESPONSE REGULATOR receiver
FIU99_RS18850	COG1566	PFAM secretion protein HlyD family protein
FIU99_RS18855	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FIU99_RS18860	COG0402	S-adenosylhomocysteine deaminase activity
FIU99_RS18865	COG0861	Integral membrane protein TerC family
FIU99_RS18875	COG0784	Response regulator, receiver
FIU99_RS18875	COG5002	protein histidine kinase activity
FIU99_RS18875	COG2205	protein histidine kinase activity
FIU99_RS18915	COG4533	DNA binding
FIU99_RS18930	COG3833	ABC-type maltose transport systems, permease component
FIU99_RS18935	COG1175	transmembrane transport
FIU99_RS18945	COG3842	ATPase activity
FIU99_RS18950	COG2096	Adenosyltransferase
FIU99_RS18955	COG0748	coenzyme F420 binding
FIU99_RS18960	COG3721	Heme iron utilization protein
FIU99_RS18970	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
FIU99_RS18975	COG0811	peptide transport
FIU99_RS18980	COG0848	biopolymer transport protein
FIU99_RS18990	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FIU99_RS18995	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FIU99_RS19000	COG2814	Major facilitator Superfamily
FIU99_RS19010	COG0739	heme binding
FIU99_RS19025	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FIU99_RS19035	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
FIU99_RS19045	COG0513	Belongs to the DEAD box helicase family
FIU99_RS19055	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FIU99_RS19055	COG4191	Histidine kinase
FIU99_RS19060	COG0784	Response regulator, receiver
FIU99_RS19060	COG3437	response regulator, receiver
FIU99_RS19065	COG1609	Transcriptional regulator
FIU99_RS19070	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FIU99_RS19075	COG1879	ABC-type sugar transport system periplasmic component
FIU99_RS19080	COG1172	Belongs to the binding-protein-dependent transport system permease family
FIU99_RS19085	COG1129	ABC transporter
FIU99_RS19090	COG1869	D-ribose catabolic process
FIU99_RS19100	COG3469	chitinase activity
FIU99_RS19115	COG0004	ammonium transporteR
FIU99_RS19140	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FIU99_RS19160	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FIU99_RS19165	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
FIU99_RS19195	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
FIU99_RS19200	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FIU99_RS19205	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FIU99_RS19210	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FIU99_RS19230	COG1609	Transcriptional regulator
FIU99_RS19235	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FIU99_RS19240	COG3265	gluconokinase activity
FIU99_RS19245	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FIU99_RS19245	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FIU99_RS19255	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FIU99_RS19280	COG0583	DNA-binding transcription factor activity
FIU99_RS19295	COG3123	guanosine phosphorylase activity
FIU99_RS19300	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FIU99_RS19310	COG0668	transmembrane transport
FIU99_RS19330	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FIU99_RS19370	COG3118	belongs to the thioredoxin family
FIU99_RS19375	COG4232	protein-disulfide reductase activity
FIU99_RS19390	COG1280	lysine exporter protein (LysE YggA)
FIU99_RS19420	COG0443	Heat shock 70 kDa protein
FIU99_RS19425	COG0583	DNA-binding transcription factor activity
FIU99_RS19435	COG4948	Mandelate Racemase Muconate Lactonizing
FIU99_RS19440	COG1396	sequence-specific DNA binding
FIU99_RS19445	COG5001	Diguanylate cyclase
FIU99_RS19455	COG3706	GGDEF domain
FIU99_RS19465	COG0642	Histidine kinase
FIU99_RS19485	COG2130	NADP-dependent
FIU99_RS19500	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FIU99_RS19530	COG0534	Mate efflux family protein
FIU99_RS19535	COG0444	Belongs to the ABC transporter superfamily
FIU99_RS19540	COG4608	Belongs to the ABC transporter superfamily
FIU99_RS19545	COG0747	negative chemotaxis
FIU99_RS19565	COG0366	Alpha amylase catalytic
FIU99_RS19595	COG3279	Response regulator of the LytR AlgR family
FIU99_RS19600	COG3275	phosphorelay sensor kinase activity
FIU99_RS19620	COG1136	(ABC) transporter
FIU99_RS19635	COG1012	belongs to the aldehyde dehydrogenase family
FIU99_RS19655	COG3530	Putative quorum-sensing-regulated virulence factor
FIU99_RS19670	COG1686	Belongs to the peptidase S11 family
FIU99_RS19685	COG3036	rescue of stalled ribosome
FIU99_RS19690	COG1278	Cold shock
FIU99_RS19705	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FIU99_RS19705	COG1017	nitric oxide dioxygenase activity
FIU99_RS19710	COG3604	Transcriptional regulator
FIU99_RS19720	COG0546	phosphoglycolate phosphatase activity
FIU99_RS19725	COG2249	NAD(P)H dehydrogenase (quinone) activity
FIU99_RS19735	COG0534	Mate efflux family protein
FIU99_RS19745	COG0697	spore germination
FIU99_RS19760	COG2814	Major facilitator Superfamily
FIU99_RS19765	COG0583	DNA-binding transcription factor activity
FIU99_RS19770	COG5001	Diguanylate cyclase
FIU99_RS19820	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
FIU99_RS19830	COG0438	transferase activity, transferring glycosyl groups
FIU99_RS19830	COG0297	glycogen (starch) synthase activity
FIU99_RS19840	COG1045	serine acetyltransferase
FIU99_RS19855	COG0438	transferase activity, transferring glycosyl groups
FIU99_RS19860	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FIU99_RS19865	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FIU99_RS19870	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FIU99_RS19875	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FIU99_RS19885	COG2203	Gaf domain
FIU99_RS19885	COG4251	negative regulation of phosphorylation
FIU99_RS19885	COG3706	GGDEF domain
FIU99_RS19885	COG5001	Diguanylate cyclase
FIU99_RS19890	COG4989	oxidoreductase activity
FIU99_RS19900	COG0366	Alpha amylase catalytic
FIU99_RS19910	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FIU99_RS19915	COG1126	abc transporter atp-binding protein
FIU99_RS19920	COG0765	amino acid transport
FIU99_RS19925	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FIU99_RS19930	COG0765	amino acid transport
FIU99_RS19935	COG0109	protoheme IX farnesyltransferase activity
FIU99_RS19940	COG1612	heme a metabolic process
FIU99_RS19965	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
FIU99_RS19970	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FIU99_RS19975	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FIU99_RS19980	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FIU99_RS20000	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FIU99_RS20010	COG3314	Sporulation integral membrane protein YlbJ
FIU99_RS20020	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FIU99_RS20045	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FIU99_RS20060	COG1741	Belongs to the pirin family
FIU99_RS20070	COG2814	Major facilitator Superfamily
FIU99_RS20075	COG1686	Belongs to the peptidase S11 family
FIU99_RS20080	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FIU99_RS20085	COG0583	DNA-binding transcription factor activity
FIU99_RS20120	COG1253	flavin adenine dinucleotide binding
FIU99_RS20160	COG1280	lysine exporter protein (LysE YggA)
FIU99_RS20165	COG0583	DNA-binding transcription factor activity
FIU99_RS20220	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FIU99_RS20225	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FIU99_RS20225	COG4451	ribulose bisphosphate carboxylase, small
FIU99_RS20230	COG0523	cobalamin synthesis protein
FIU99_RS20235	COG2988	succinylglutamate desuccinylase activity
FIU99_RS20240	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
FIU99_RS20280	COG1846	Transcriptional regulator
FIU99_RS20290	COG1280	lysine exporter protein (LysE YggA)
FIU99_RS20300	COG1177	transmembrane transport
FIU99_RS20305	COG1176	ABC-type spermidine putrescine transport system, permease component I
FIU99_RS20310	COG3842	ATPase activity
FIU99_RS20315	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FIU99_RS20320	COG2423	ornithine cyclodeaminase activity
FIU99_RS20335	COG3938	Belongs to the proline racemase family
FIU99_RS20345	COG2186	Transcriptional regulator
FIU99_RS20360	COG0601	transmembrane transport
FIU99_RS20365	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FIU99_RS20380	COG0006	proline dipeptidase activity
FIU99_RS20415	COG3568	Endonuclease Exonuclease Phosphatase
FIU99_RS20425	COG3291	Pkd domain containing protein
FIU99_RS20430	COG0513	Belongs to the DEAD box helicase family
FIU99_RS20440	COG1388	LysM domain
FIU99_RS20440	COG1376	ErfK ybiS ycfS ynhG family protein
FIU99_RS20445	COG0415	Belongs to the DNA photolyase family
FIU99_RS20450	COG0789	Transcriptional regulator
FIU99_RS20455	COG3272	Protein of unknown function (DUF1722)
FIU99_RS20460	COG0813	purine-nucleoside phosphorylase activity
FIU99_RS20475	COG3706	GGDEF domain
FIU99_RS20490	COG1566	PFAM secretion protein HlyD family protein
FIU99_RS20495	COG0786	glutamate:sodium symporter activity
FIU99_RS20505	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FIU99_RS20520	COG0583	DNA-binding transcription factor activity
FIU99_RS20530	COG1132	(ABC) transporter
FIU99_RS20575	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FIU99_RS20585	COG0259	pyridoxamine-phosphate oxidase activity
FIU99_RS20615	COG3033	Beta-eliminating lyase
FIU99_RS20620	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
FIU99_RS20625	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FIU99_RS20630	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FIU99_RS20640	COG1999	signal sequence binding
FIU99_RS20655	COG1671	Belongs to the UPF0178 family
FIU99_RS20660	COG0393	Putative heavy-metal-binding
FIU99_RS20665	COG0583	DNA-binding transcription factor activity
FIU99_RS20670	COG2814	Major facilitator Superfamily
FIU99_RS20705	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FIU99_RS20715	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FIU99_RS20725	COG0346	lactoylglutathione lyase activity
FIU99_RS20750	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FIU99_RS20905	COG1301	dicarboxylic acid transport
FIU99_RS20925	COG2207	Transcriptional regulator
FIU99_RS20935	COG0700	Nucleoside recognition
FIU99_RS20940	COG3366	ferrous iron transmembrane transporter activity
FIU99_RS20945	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FIU99_RS20960	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FIU99_RS20970	COG0745	RESPONSE REGULATOR receiver
FIU99_RS20975	COG5002	protein histidine kinase activity
FIU99_RS20990	COG4999	Histidine kinase
FIU99_RS20990	COG3850	Histidine kinase
FIU99_RS20990	COG3437	response regulator, receiver
FIU99_RS20990	COG2205	protein histidine kinase activity
FIU99_RS20995	COG0745	RESPONSE REGULATOR receiver
FIU99_RS21000	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FIU99_RS21010	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FIU99_RS21035	COG0745	RESPONSE REGULATOR receiver
FIU99_RS21040	COG2205	protein histidine kinase activity
FIU99_RS21045	COG0471	metal ion transport
FIU99_RS21075	COG3314	Sporulation integral membrane protein YlbJ
FIU99_RS21085	COG1595	DNA-templated transcription, initiation
FIU99_RS21100	COG0697	spore germination
FIU99_RS21105	COG0251	oxidation-reduction process
FIU99_RS21115	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FIU99_RS21115	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FIU99_RS21125	COG1063	alcohol dehydrogenase
FIU99_RS21145	COG0583	DNA-binding transcription factor activity
FIU99_RS21165	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FIU99_RS21175	COG1175	transmembrane transport
FIU99_RS21190	COG1940	carbohydrate kinase activity
FIU99_RS21200	COG0438	transferase activity, transferring glycosyl groups
FIU99_RS21210	COG0671	phosphoesterase, PA-phosphatase related
FIU99_RS21220	COG3708	Transcriptional regulator
FIU99_RS21220	COG2207	Transcriptional regulator
FIU99_RS21240	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FIU99_RS21245	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FIU99_RS21250	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FIU99_RS21255	COG1116	anion transmembrane transporter activity
FIU99_RS21260	COG0351	phosphomethylpyrimidine kinase
FIU99_RS21265	COG0656	L-ascorbic acid biosynthetic process
FIU99_RS21270	COG0604	alcohol dehydrogenase
FIU99_RS21270	COG1028	Short-chain dehydrogenase reductase Sdr
FIU99_RS21270	COG3321	synthase
FIU99_RS21285	COG0583	DNA-binding transcription factor activity
FIU99_RS21305	COG0840	transmembrane signaling receptor activity
FIU99_RS21310	COG0768	penicillin binding
FIU99_RS21315	COG2723	6-phospho-beta-galactosidase activity
FIU99_RS21320	COG0589	response to stress
FIU99_RS21325	COG3842	ATPase activity
FIU99_RS21330	COG0546	phosphoglycolate phosphatase activity
FIU99_RS21350	COG1175	transmembrane transport
FIU99_RS21355	COG0583	DNA-binding transcription factor activity
FIU99_RS21390	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FIU99_RS21415	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FIU99_RS21460	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FIU99_RS21465	COG0840	transmembrane signaling receptor activity
FIU99_RS21470	COG0835	chemotaxis
FIU99_RS21495	COG0840	transmembrane signaling receptor activity
FIU99_RS21500	COG1444	tRNA N-acetyltransferase activity
FIU99_RS21530	COG4608	Belongs to the ABC transporter superfamily
FIU99_RS21535	COG0444	Belongs to the ABC transporter superfamily
FIU99_RS21570	COG1028	Short-chain dehydrogenase reductase Sdr
FIU99_RS21580	COG1028	Short-chain dehydrogenase reductase Sdr
FIU99_RS21585	COG1733	regulation of RNA biosynthetic process
FIU99_RS21605	COG0583	DNA-binding transcription factor activity
FIU99_RS21610	COG1051	belongs to the nudix hydrolase family
FIU99_RS21625	COG3300	MHYT domain
FIU99_RS21625	COG5001	Diguanylate cyclase
FIU99_RS21630	COG0697	spore germination
FIU99_RS21635	COG1846	Transcriptional regulator
FIU99_RS21665	COG1288	antiporter activity
FIU99_RS21670	COG0583	DNA-binding transcription factor activity
FIU99_RS21680	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FIU99_RS21685	COG3960	tartronate-semialdehyde synthase activity
FIU99_RS21690	COG3622	Belongs to the hyi family
FIU99_RS21695	COG2084	Dehydrogenase
FIU99_RS21710	COG2015	COG2015, Alkyl sulfatase and related hydrolases
FIU99_RS21725	COG0559	Belongs to the binding-protein-dependent transport system permease family
FIU99_RS21750	COG0831	urea catabolic process
FIU99_RS21755	COG0832	Belongs to the urease beta subunit family
FIU99_RS21760	COG0804	urea catabolic process
FIU99_RS21765	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
FIU99_RS21810	COG0840	transmembrane signaling receptor activity
FIU99_RS21815	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FIU99_RS21830	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
FIU99_RS21840	COG4145	pantothenate transmembrane transporter activity
FIU99_RS21845	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FIU99_RS21850	COG0800	Aldolase
FIU99_RS21860	COG2706	6-phosphogluconolactonase activity
FIU99_RS21870	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FIU99_RS21875	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FIU99_RS21880	COG1845	cytochrome c oxidase, subunit III
FIU99_RS21885	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FIU99_RS21890	COG0109	protoheme IX farnesyltransferase activity
FIU99_RS21905	COG3179	chitinase
FIU99_RS21935	COG0583	DNA-binding transcription factor activity
FIU99_RS21945	COG2205	protein histidine kinase activity
FIU99_RS21960	COG3214	Protein conserved in bacteria
FIU99_RS21965	COG0596	Alpha beta hydrolase
FIU99_RS21980	COG2252	PERMEase
FIU99_RS22000	COG4266	Belongs to the allantoicase family
FIU99_RS22015	COG0840	transmembrane signaling receptor activity
FIU99_RS22025	COG1522	sequence-specific DNA binding
FIU99_RS22035	COG5002	protein histidine kinase activity
FIU99_RS22035	COG2205	protein histidine kinase activity
FIU99_RS22035	COG0784	Response regulator, receiver
FIU99_RS22040	COG2226	methyltransferase
FIU99_RS22045	COG0402	S-adenosylhomocysteine deaminase activity
FIU99_RS22055	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FIU99_RS22065	COG2186	Transcriptional regulator
FIU99_RS22090	COG3795	YCII-related domain
FIU99_RS22120	COG0402	S-adenosylhomocysteine deaminase activity
FIU99_RS22125	COG1404	Belongs to the peptidase S8 family
FIU99_RS22130	COG1335	isochorismatase
FIU99_RS22135	COG2207	Transcriptional regulator
FIU99_RS22170	COG0456	acetyltransferase
FIU99_RS22180	COG2909	trisaccharide binding
FIU99_RS22185	COG0058	SHG alpha-glucan phosphorylase activity
FIU99_RS22190	COG1640	4-alpha-glucanotransferase
FIU99_RS22195	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FIU99_RS22210	COG1619	proteins homologs of microcin C7 resistance protein MccF
FIU99_RS22260	COG2249	NAD(P)H dehydrogenase (quinone) activity
FIU99_RS22270	COG0583	DNA-binding transcription factor activity
FIU99_RS22280	COG0300	oxidoreductase activity
FIU99_RS22330	COG0561	phosphatase activity
FIU99_RS22370	COG1132	(ABC) transporter
FIU99_RS22375	COG1132	(ABC) transporter
FIU99_RS22380	COG1021	2,3-dihydroxybenzoate-AMP ligase
FIU99_RS22385	COG1169	isochorismate synthase
FIU99_RS22405	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FIU99_RS22405	COG2226	methyltransferase
FIU99_RS22405	COG3433	isochorismatase activity
FIU99_RS22410	COG2814	Major facilitator Superfamily
FIU99_RS22415	COG4771	TonB-dependent receptor
FIU99_RS22420	COG4977	sequence-specific DNA binding
FIU99_RS22420	COG1917	Cupin 2, conserved barrel domain protein
FIU99_RS22440	COG1733	regulation of RNA biosynthetic process
FIU99_RS22485	COG0702	epimerase
FIU99_RS22510	COG1414	Transcriptional regulator
FIU99_RS22515	COG1028	Short-chain dehydrogenase reductase Sdr
FIU99_RS22525	COG0583	DNA-binding transcription factor activity
FIU99_RS22550	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FIU99_RS22550	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
FIU99_RS22550	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FIU99_RS22555	COG0383	alpha-mannosidase activity
FIU99_RS22565	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FIU99_RS22565	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FIU99_RS22565	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FIU99_RS22570	COG4968	Prepilin-type N-terminal cleavage methylation domain
FIU99_RS22580	COG2814	Major facilitator Superfamily
FIU99_RS22585	COG1120	ATPase activity
FIU99_RS22600	COG4264	IucA IucC family
FIU99_RS22625	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FIU99_RS22635	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FIU99_RS22645	COG0662	Cupin 2, conserved barrel domain protein
FIU99_RS22650	COG1960	acyl-CoA dehydrogenase activity
FIU99_RS22655	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FIU99_RS22660	COG2076	Multidrug Resistance protein
FIU99_RS22665	COG2076	Multidrug Resistance protein
FIU99_RS22670	COG0590	tRNA wobble adenosine to inosine editing
FIU99_RS22725	COG0657	acetylesterase activity
FIU99_RS22735	COG4175	Glycine betaine
FIU99_RS22735	COG3448	diguanylate cyclase activity
FIU99_RS22740	COG4176	ABC-type proline glycine betaine transport system permease component
FIU99_RS22760	COG2095	MarC family integral membrane protein
FIU99_RS22795	COG4964	Belongs to the GSP D family
FIU99_RS22805	COG2894	cell division
FIU99_RS22860	COG1477	protein flavinylation
FIU99_RS22880	COG4221	oxidoreductase activity
FIU99_RS22885	COG0840	transmembrane signaling receptor activity
FIU99_RS22895	COG0573	inorganic phosphate transmembrane transporter activity
FIU99_RS22900	COG0581	inorganic phosphate transmembrane transporter activity
FIU99_RS22905	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FIU99_RS22920	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
FIU99_RS22925	COG1162	GTPase activity
FIU99_RS22945	COG1122	ATPase activity
FIU99_RS22950	COG4720	Psort location CytoplasmicMembrane, score
FIU99_RS22955	COG0363	glucosamine-6-phosphate deaminase activity
FIU99_RS22970	COG0454	-acetyltransferase
FIU99_RS22975	COG0840	transmembrane signaling receptor activity
FIU99_RS23005	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FIU99_RS23010	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FIU99_RS23015	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
FIU99_RS23025	COG1522	sequence-specific DNA binding
FIU99_RS23055	COG3608	succinylglutamate desuccinylase aspartoacylase
FIU99_RS23060	COG1288	antiporter activity
FIU99_RS23075	COG0745	RESPONSE REGULATOR receiver
FIU99_RS23110	COG3314	Sporulation integral membrane protein YlbJ
FIU99_RS23120	COG0583	DNA-binding transcription factor activity
FIU99_RS23125	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FIU99_RS23130	COG1151	hydroxylamine reductase activity
FIU99_RS23140	COG0583	DNA-binding transcription factor activity
FIU99_RS23160	COG3604	Transcriptional regulator
FIU99_RS23190	COG0415	Belongs to the DNA photolyase family
FIU99_RS23195	COG3046	protein related to deoxyribodipyrimidine photolyase
FIU99_RS23205	COG2329	Antibiotic biosynthesis monooxygenase
FIU99_RS23210	COG3304	Inner membrane component domain
FIU99_RS23230	COG0583	DNA-binding transcription factor activity
FIU99_RS23235	COG1234	tRNA 3'-trailer cleavage
FIU99_RS23265	COG0004	ammonium transporteR
FIU99_RS23275	COG3383	formate dehydrogenase (NAD+) activity
FIU99_RS23280	COG0446	pyridine nucleotide-disulphide oxidoreductase
FIU99_RS23285	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FIU99_RS23290	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FIU99_RS23315	COG0739	heme binding
FIU99_RS23320	COG3047	cAMP biosynthetic process
FIU99_RS23345	COG0300	oxidoreductase activity
FIU99_RS23350	COG5553	Cysteine dioxygenase type I
FIU99_RS23360	COG0673	inositol 2-dehydrogenase activity
FIU99_RS23365	COG0488	(ABC) transporter
FIU99_RS23395	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FIU99_RS23395	COG4191	Histidine kinase
FIU99_RS23400	COG1320	monovalent cation:proton antiporter activity
FIU99_RS23405	COG2212	antiporter activity
FIU99_RS23410	COG1863	multisubunit Na H antiporter MnhE subunit
FIU99_RS23415	COG0651	ATP synthesis coupled electron transport
FIU99_RS23420	COG1006	Multisubunit Na H antiporter MnhC subunit
FIU99_RS23425	COG2111	Na H antiporter
FIU99_RS23425	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FIU99_RS23435	COG0589	response to stress
FIU99_RS23440	COG1132	(ABC) transporter
FIU99_RS23450	COG0583	DNA-binding transcription factor activity
FIU99_RS23470	COG0509	glycine decarboxylation via glycine cleavage system
FIU99_RS23475	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FIU99_RS23485	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FIU99_RS23500	COG4580	involved in the transport of maltose and maltodextrins
FIU99_RS23510	COG0840	transmembrane signaling receptor activity
FIU99_RS23540	COG0840	transmembrane signaling receptor activity
FIU99_RS23570	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FIU99_RS23580	COG0415	Belongs to the DNA photolyase family
FIU99_RS23600	COG0697	spore germination
FIU99_RS23635	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FIU99_RS23635	COG2207	Transcriptional regulator
FIU99_RS23640	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FIU99_RS23660	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FIU99_RS23670	COG1522	sequence-specific DNA binding
FIU99_RS23695	COG1357	PFAM Pentapeptide repeats (8 copies)
FIU99_RS23705	COG1294	oxidase, subunit
FIU99_RS23710	COG1271	oxidase subunit
FIU99_RS23715	COG1805	sodium ion transport
FIU99_RS23740	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FIU99_RS23765	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FIU99_RS23775	COG1309	transcriptional regulator
FIU99_RS23795	COG0745	RESPONSE REGULATOR receiver
FIU99_RS23800	COG5002	protein histidine kinase activity
FIU99_RS23835	COG0842	Transport permease protein
FIU99_RS23840	COG1131	(ABC) transporter
FIU99_RS23875	COG1054	Belongs to the UPF0176 family
FIU99_RS23880	COG0346	lactoylglutathione lyase activity
FIU99_RS23885	COG0625	glutathione transferase activity
FIU99_RS23890	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FIU99_RS23900	COG0366	Alpha amylase catalytic
FIU99_RS23920	COG2084	Dehydrogenase
FIU99_RS23935	COG2130	NADP-dependent
FIU99_RS23940	COG1309	transcriptional regulator
FIU99_RS23945	COG3706	GGDEF domain
FIU99_RS23960	COG3097	Belongs to the UPF0267 family
FIU99_RS23965	COG0513	Belongs to the DEAD box helicase family
FIU99_RS23975	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FIU99_RS24015	COG0573	inorganic phosphate transmembrane transporter activity
FIU99_RS24025	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FIU99_RS24040	COG1175	transmembrane transport
FIU99_RS24045	COG0395	ABC-type sugar transport system, permease component
FIU99_RS24050	COG1554	hydrolase, family 65, central catalytic
FIU99_RS24055	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FIU99_RS24060	COG3842	ATPase activity
FIU99_RS24070	COG1621	beta-fructofuranosidase activity
FIU99_RS24080	COG0110	maltose O-acetyltransferase activity
FIU99_RS24120	COG0251	oxidation-reduction process
FIU99_RS24150	COG0564	pseudouridine synthase activity
FIU99_RS24175	COG0583	DNA-binding transcription factor activity
FIU99_RS24180	COG2814	Major facilitator Superfamily
FIU99_RS24205	COG0840	transmembrane signaling receptor activity
FIU99_RS24210	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FIU99_RS24220	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FIU99_RS24225	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FIU99_RS24230	COG0579	oxidoreductase
FIU99_RS24260	COG1012	belongs to the aldehyde dehydrogenase family
FIU99_RS24265	COG3284	Transcriptional regulator
FIU99_RS24285	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FIU99_RS24290	COG0363	glucosamine-6-phosphate deaminase activity
FIU99_RS24295	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FIU99_RS24300	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FIU99_RS24310	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FIU99_RS24320	COG2271	Major facilitator Superfamily
FIU99_RS24325	COG3851	Histidine kinase
FIU99_RS24330	COG2197	response regulator
FIU99_RS24350	COG0418	dihydroorotase activity
FIU99_RS24355	COG3217	Mosc domain protein beta barrel domain protein
FIU99_RS24355	COG0633	Ferredoxin
FIU99_RS24355	COG0633	Ferredoxin
FIU99_RS24355	COG3217	Mosc domain protein beta barrel domain protein
FIU99_RS24365	COG1349	DNA-binding transcription factor activity
FIU99_RS24370	COG2199	diguanylate cyclase activity
FIU99_RS24390	COG2354	Protein conserved in bacteria
FIU99_RS24400	COG0366	Alpha amylase catalytic
FIU99_RS24440	COG0840	transmembrane signaling receptor activity
FIU99_RS24445	COG1366	Belongs to the anti-sigma-factor antagonist family
FIU99_RS24455	COG2172	sigma factor antagonist activity
FIU99_RS24465	COG2205	protein histidine kinase activity
FIU99_RS24465	COG3437	response regulator, receiver
FIU99_RS24465	COG3850	Histidine kinase
FIU99_RS24465	COG4999	Histidine kinase
FIU99_RS24470	COG3437	response regulator, receiver
FIU99_RS24485	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FIU99_RS24485	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FIU99_RS24490	COG0516	GMP reductase activity
FIU99_RS24500	COG1346	cytolysis
FIU99_RS24505	COG1404	Belongs to the peptidase S8 family
FIU99_RS24520	COG1309	transcriptional regulator
FIU99_RS24525	COG1012	belongs to the aldehyde dehydrogenase family
FIU99_RS24545	COG4175	Glycine betaine
FIU99_RS24545	COG3448	diguanylate cyclase activity
FIU99_RS24565	COG1304	FMN binding
FIU99_RS24570	COG1620	l-lactate permease
FIU99_RS24575	COG0583	DNA-binding transcription factor activity
FIU99_RS24580	COG4172	Belongs to the ABC transporter superfamily
FIU99_RS24590	COG1067	ATP-dependent peptidase activity
FIU99_RS24595	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FIU99_RS24600	COG0840	transmembrane signaling receptor activity
FIU99_RS24615	COG4166	transmembrane transport
FIU99_RS24620	COG4174	ABC transporter (Permease)
FIU99_RS24625	COG4239	(ABC) transporter, permease
FIU99_RS24630	COG4172	Belongs to the ABC transporter superfamily
FIU99_RS24680	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FIU99_RS24685	COG4605	iron ion homeostasis
FIU99_RS24690	COG4604	ABC transporter, ATP-binding protein
FIU99_RS24695	COG2759	Belongs to the formate--tetrahydrofolate ligase family
FIU99_RS24710	COG0004	ammonium transporteR
FIU99_RS24720	COG4206	TonB-dependent receptor
FIU99_RS24740	COG2271	Major facilitator Superfamily
FIU99_RS24750	COG0840	transmembrane signaling receptor activity
FIU99_RS24755	COG2203	Gaf domain
FIU99_RS24755	COG2199	diguanylate cyclase activity
FIU99_RS24765	COG0739	heme binding
FIU99_RS24790	COG0735	belongs to the Fur family
FIU99_RS24795	COG1280	lysine exporter protein (LysE YggA)
FIU99_RS24805	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FIU99_RS24815	COG1609	Transcriptional regulator
FIU99_RS24865	COG2026	Addiction module toxin, RelE StbE family
FIU99_RS24910	COG0583	DNA-binding transcription factor activity
FIU99_RS24915	COG1028	Short-chain dehydrogenase reductase Sdr
FIU99_RS24925	COG4974	Belongs to the 'phage' integrase family
FIU99_RS24935	COG4771	TonB-dependent receptor
FIU99_RS25070	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FIU99_RS25175	COG2003	Belongs to the UPF0758 family
FIU99_RS25215	COG2203	Gaf domain
FIU99_RS25215	COG5001	Diguanylate cyclase
FIU99_RS25215	COG3706	GGDEF domain
FIU99_RS25215	COG4251	negative regulation of phosphorylation
FIU99_RS25225	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FIU99_RS25260	COG2267	carboxylic ester hydrolase activity
FIU99_RS25285	COG2169	Transcriptional regulator
FIU99_RS25290	COG1335	isochorismatase
FIU99_RS25300	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
FIU99_RS25350	COG2169	Transcriptional regulator
FIU99_RS25350	COG1917	Cupin 2, conserved barrel domain protein
FIU99_RS25380	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FIU99_RS25385	COG0459	protein refolding
FIU99_RS25390	COG0071	Belongs to the small heat shock protein (HSP20) family
FIU99_RS25410	COG1472	Belongs to the glycosyl hydrolase 3 family
FIU99_RS25420	COG4580	involved in the transport of maltose and maltodextrins
FIU99_RS25430	COG1609	Transcriptional regulator
FIU99_RS25450	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FIU99_RS25455	COG0444	Belongs to the ABC transporter superfamily
FIU99_RS25460	COG4608	Belongs to the ABC transporter superfamily
FIU99_RS25470	COG1917	Cupin 2, conserved barrel domain protein
FIU99_RS25470	COG2207	Transcriptional regulator
FIU99_RS25495	COG0583	DNA-binding transcription factor activity
FIU99_RS25500	COG0625	glutathione transferase activity
FIU99_RS25520	COG1917	Cupin 2, conserved barrel domain protein
FIU99_RS25520	COG2207	Transcriptional regulator
FIU99_RS25525	COG1280	lysine exporter protein (LysE YggA)
FIU99_RS25560	COG0583	DNA-binding transcription factor activity
FIU99_RS25570	COG2274	protein secretion by the type I secretion system
FIU99_RS25580	COG2274	protein secretion by the type I secretion system
FIU99_RS25590	COG1028	Short-chain dehydrogenase reductase Sdr
FIU99_RS25605	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FIU99_RS25605	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
FIU99_RS25640	COG1051	belongs to the nudix hydrolase family
FIU99_RS25645	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FIU99_RS25675	COG0583	DNA-binding transcription factor activity
FIU99_RS25685	COG0251	oxidation-reduction process
FIU99_RS25690	COG1742	UPF0060 membrane protein
FIU99_RS25735	COG0494	nUDIX hydrolase
FIU99_RS25760	COG4774	siderophore transport
FIU99_RS25835	COG2084	Dehydrogenase
FIU99_RS25845	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FIU99_RS25950	COG1028	Short-chain dehydrogenase reductase Sdr
FIU99_RS25955	COG0583	DNA-binding transcription factor activity
FIU99_RS25965	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
FIU99_RS25985	COG0702	epimerase
FIU99_RS26000	COG0604	alcohol dehydrogenase
FIU99_RS26015	COG3246	L-lysine catabolic process to acetate
FIU99_RS26025	COG0183	Belongs to the thiolase family
FIU99_RS26030	COG0113	porphobilinogen synthase activity
FIU99_RS26045	COG0671	phosphoesterase, PA-phosphatase related
FIU99_RS26115	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
FIU99_RS26145	COG2205	protein histidine kinase activity
FIU99_RS26150	COG0745	RESPONSE REGULATOR receiver
FIU99_RS26160	COG3527	Alpha-acetolactate decarboxylase
FIU99_RS26170	COG0583	DNA-binding transcription factor activity
FIU99_RS26175	COG1028	Short-chain dehydrogenase reductase Sdr
FIU99_RS26185	COG0745	RESPONSE REGULATOR receiver
FIU99_RS26195	COG5001	Diguanylate cyclase
FIU99_RS26195	COG4251	negative regulation of phosphorylation
FIU99_RS26195	COG2203	Gaf domain
FIU99_RS26195	COG3706	GGDEF domain
FIU99_RS26210	COG0840	transmembrane signaling receptor activity
FIU99_RS26230	COG0583	DNA-binding transcription factor activity
FIU99_RS26235	COG0583	DNA-binding transcription factor activity
FIU99_RS26240	COG0431	NADPH-dependent FMN reductase
FIU99_RS26255	COG4251	negative regulation of phosphorylation
FIU99_RS26255	COG3706	GGDEF domain
FIU99_RS26255	COG2203	Gaf domain
FIU99_RS26255	COG5001	Diguanylate cyclase
FIU99_RS26270	COG1879	ABC-type sugar transport system periplasmic component
FIU99_RS26280	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
FIU99_RS26305	COG0702	epimerase
FIU99_RS26325	COG1360	Flagellar Motor Protein
FIU99_RS26330	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FIU99_RS26335	COG1309	transcriptional regulator
FIU99_RS26390	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FIU99_RS26390	COG4191	Histidine kinase
FIU99_RS26405	COG5001	Diguanylate cyclase
FIU99_RS26405	COG3300	MHYT domain
FIU99_RS26410	COG4191	Histidine kinase
FIU99_RS26465	COG2814	Major facilitator Superfamily
FIU99_RS26475	COG1192	Involved in chromosome partitioning
FIU99_RS26490	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FIU99_RS26555	COG4191	Histidine kinase
FIU99_RS26560	COG1181	Belongs to the D-alanine--D-alanine ligase family
FIU99_RS26580	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FIU99_RS26590	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FIU99_RS26590	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FIU99_RS26780	COG0629	single-stranded DNA binding
FIU99_RS26820	COG0776	regulation of translation
FIU99_RS26935	COG1959	2 iron, 2 sulfur cluster binding
FIU99_RS27110	COG0860	N-Acetylmuramoyl-L-alanine amidase
FIU99_RS27110	COG2247	cell wall binding repeat
FIU99_RS27150	COG3093	addiction module antidote protein HigA
FIU99_RS27155	COG3549	Plasmid maintenance system killer
FIU99_RS27190	COG5301	cellulose 1,4-beta-cellobiosidase activity