locus-tag	class	description
G5S32_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
G5S32_RS00010	COG0592	DNA-directed DNA polymerase activity
G5S32_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
G5S32_RS00020	COG0187	DNA topoisomerase II activity
G5S32_RS00035	COG0071	Belongs to the small heat shock protein (HSP20) family
G5S32_RS00040	COG3977	Valine--pyruvate aminotransferase
G5S32_RS00045	COG0751	glycine-tRNA ligase activity
G5S32_RS00050	COG0752	glycyl-tRNA synthetase alpha subunit
G5S32_RS00055	COG2119	membrane
G5S32_RS00080	COG0604	alcohol dehydrogenase
G5S32_RS00095	COG0129	dihydroxy-acid dehydratase activity
G5S32_RS00100	COG3978	acetolactate synthase activity
G5S32_RS00110	COG0606	chelatase, subunit chli
G5S32_RS00115	COG0204	Acyl-transferase
G5S32_RS00120	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
G5S32_RS00125	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
G5S32_RS00135	COG3084	Protein conserved in bacteria
G5S32_RS00145	COG4326	sporulation control protein
G5S32_RS00150	COG1272	protein, Hemolysin III
G5S32_RS00160	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
G5S32_RS00165	COG0569	domain protein
G5S32_RS00170	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
G5S32_RS00170	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
G5S32_RS00180	COG0242	peptide deformylase activity
G5S32_RS00190	COG0758	DNA mediated transformation
G5S32_RS00195	COG2922	Belongs to the Smg family
G5S32_RS00200	COG0551	DNA topoisomerase type I activity
G5S32_RS00205	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
G5S32_RS00210	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
G5S32_RS00220	COG0408	coproporphyrinogen oxidase activity
G5S32_RS00235	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
G5S32_RS00280	COG0583	DNA-binding transcription factor activity
G5S32_RS00285	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
G5S32_RS00290	COG2960	long-chain fatty acid transporting porin activity
G5S32_RS00295	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G5S32_RS00300	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G5S32_RS00305	COG0210	DNA helicase
G5S32_RS00340	COG4172	Belongs to the ABC transporter superfamily
G5S32_RS00355	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G5S32_RS00365	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G5S32_RS00370	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G5S32_RS00385	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G5S32_RS00390	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
G5S32_RS00395	COG0339	signal peptide processing
G5S32_RS00410	COG3220	belongs to the UPF0276 family
G5S32_RS00420	COG0210	DNA helicase
G5S32_RS00425	COG1280	lysine exporter protein (LysE YggA)
G5S32_RS00435	COG2962	Rard protein
G5S32_RS00440	COG0514	ATP-dependent DNA helicase (RecQ)
G5S32_RS00450	COG1132	(ABC) transporter
G5S32_RS00460	COG1120	ATPase activity
G5S32_RS00465	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
G5S32_RS00470	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G5S32_RS00480	COG0742	ribosomal rna small subunit methyltransferase
G5S32_RS00485	COG0552	protein localization to endoplasmic reticulum
G5S32_RS00490	COG2884	Cell division ATP-binding protein ftsE
G5S32_RS00495	COG2177	Part of the ABC transporter FtsEX involved in
G5S32_RS00500	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
G5S32_RS00505	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
G5S32_RS00510	COG0705	Rhomboid family
G5S32_RS00515	COG1580	Controls the rotational direction of flagella during chemotaxis
G5S32_RS00520	COG3161	chorismate lyase activity
G5S32_RS00525	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
G5S32_RS00530	COG2937	Belongs to the GPAT DAPAT family
G5S32_RS00535	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
G5S32_RS00540	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
G5S32_RS00550	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G5S32_RS00570	COG4206	TonB-dependent receptor
G5S32_RS00575	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
G5S32_RS00630	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
G5S32_RS00635	COG5001	Diguanylate cyclase
G5S32_RS00635	COG3300	MHYT domain
G5S32_RS00640	COG2204	response regulator
G5S32_RS00645	COG3852	Histidine kinase
G5S32_RS00650	COG0174	glutamine synthetase
G5S32_RS00665	COG1490	D-aminoacyl-tRNA deacylase activity
G5S32_RS00670	COG0456	acetyltransferase
G5S32_RS00680	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
G5S32_RS00690	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
G5S32_RS00695	COG3031	protein transport across the cell outer membrane
G5S32_RS00705	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
G5S32_RS00710	COG1459	type II secretion system
G5S32_RS00715	COG2165	general secretion pathway protein
G5S32_RS00720	COG2165	general secretion pathway protein
G5S32_RS00725	COG2165	general secretion pathway protein
G5S32_RS00730	COG4795	General secretion pathway protein
G5S32_RS00735	COG3156	type II secretion system protein K
G5S32_RS00740	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
G5S32_RS00745	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
G5S32_RS00755	COG1218	3'(2'),5'-bisphosphate nucleotidase
G5S32_RS00760	COG0494	nUDIX hydrolase
G5S32_RS00785	COG2183	response to ionizing radiation
G5S32_RS00795	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
G5S32_RS00800	COG0745	RESPONSE REGULATOR receiver
G5S32_RS00810	COG2233	PERMEase
G5S32_RS00815	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
G5S32_RS00820	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
G5S32_RS00825	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
G5S32_RS00830	COG1758	RNA polymerase activity
G5S32_RS00835	COG0194	GDP metabolic process
G5S32_RS00840	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
G5S32_RS00845	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G5S32_RS00865	COG4232	protein-disulfide reductase activity
G5S32_RS00870	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
G5S32_RS00880	COG3706	GGDEF domain
G5S32_RS00885	COG3030	protein affecting phage T7 exclusion by the F plasmid
G5S32_RS00890	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
G5S32_RS00895	COG2205	protein histidine kinase activity
G5S32_RS00900	COG0745	RESPONSE REGULATOR receiver
G5S32_RS00910	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
G5S32_RS00915	COG0205	6-phosphofructokinase activity
G5S32_RS00920	COG1494	fructose-1,6-bisphosphatase
G5S32_RS00930	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
G5S32_RS00935	COG0527	aspartate kinase activity
G5S32_RS00935	COG0460	homoserine dehydrogenase
G5S32_RS00940	COG0626	cystathionine gamma-synthase activity
G5S32_RS00950	COG0281	malic enzyme
G5S32_RS00955	COG0254	rRNA binding
G5S32_RS00960	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
G5S32_RS00965	COG1609	Transcriptional regulator
G5S32_RS00975	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
G5S32_RS00980	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
G5S32_RS00985	COG1575	Belongs to the MenA family. Type 1 subfamily
G5S32_RS00995	COG0534	Mate efflux family protein
G5S32_RS01000	COG0149	triose-phosphate isomerase activity
G5S32_RS01030	COG0459	protein refolding
G5S32_RS01035	COG3866	Pectate lyase
G5S32_RS01040	COG3866	Pectate lyase
G5S32_RS01050	COG2755	lipolytic protein G-D-S-L family
G5S32_RS01055	COG2755	lipolytic protein G-D-S-L family
G5S32_RS01065	COG1119	ATPase activity
G5S32_RS01070	COG1509	lysine 2,3-aminomutase activity
G5S32_RS01075	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
G5S32_RS01085	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
G5S32_RS01090	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
G5S32_RS01095	COG1053	succinate dehydrogenase
G5S32_RS01100	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
G5S32_RS01105	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
G5S32_RS01110	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
G5S32_RS01115	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
G5S32_RS01120	COG1045	serine acetyltransferase
G5S32_RS01125	COG1695	Transcriptional regulator
G5S32_RS01130	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
G5S32_RS01135	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G5S32_RS01140	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
G5S32_RS01145	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
G5S32_RS01150	COG0137	argininosuccinate synthase activity
G5S32_RS01155	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
G5S32_RS01155	COG0165	Argininosuccinate lyase
G5S32_RS01170	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
G5S32_RS01200	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
G5S32_RS01205	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
G5S32_RS01215	COG0338	D12 class N6 adenine-specific DNA methyltransferase
G5S32_RS01220	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
G5S32_RS01225	COG0546	phosphoglycolate phosphatase activity
G5S32_RS01230	COG0180	Tryptophanyl-tRNA synthetase
G5S32_RS01240	COG0446	pyridine nucleotide-disulphide oxidoreductase
G5S32_RS01250	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
G5S32_RS01260	COG1012	belongs to the aldehyde dehydrogenase family
G5S32_RS01275	COG3954	Phosphoribulokinase
G5S32_RS01285	COG0429	hydrolase of the alpha beta-hydrolase fold
G5S32_RS01295	COG0488	(ABC) transporter
G5S32_RS01300	COG2249	NAD(P)H dehydrogenase (quinone) activity
G5S32_RS01310	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
G5S32_RS01315	COG1047	Peptidyl-prolyl cis-trans
G5S32_RS01320	COG1446	asparaginase
G5S32_RS01325	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
G5S32_RS01330	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
G5S32_RS01335	COG0557	exoribonuclease II activity
G5S32_RS01340	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
G5S32_RS01345	COG0051	transcription antitermination factor activity, RNA binding
G5S32_RS01355	COG0088	Forms part of the polypeptide exit tunnel
G5S32_RS01360	COG0089	rRNA binding
G5S32_RS01370	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
G5S32_RS01375	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
G5S32_RS01380	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
G5S32_RS01385	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
G5S32_RS01390	COG0255	Belongs to the universal ribosomal protein uL29 family
G5S32_RS01395	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
G5S32_RS01400	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
G5S32_RS01410	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
G5S32_RS01420	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
G5S32_RS01440	COG1841	ribosomal large subunit assembly
G5S32_RS01450	COG0201	protein transport
G5S32_RS01455	COG0257	Belongs to the bacterial ribosomal protein bL36 family
G5S32_RS01460	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
G5S32_RS01465	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
G5S32_RS01470	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
G5S32_RS01480	COG0203	ribosomal protein L17
G5S32_RS01485	COG2873	o-acetylhomoserine
G5S32_RS01490	COG0545	Peptidyl-prolyl cis-trans isomerase
G5S32_RS01495	COG3061	Opacity-associated protein A
G5S32_RS01505	COG2153	protein acetylation
G5S32_RS01510	COG0513	Belongs to the DEAD box helicase family
G5S32_RS01520	COG0737	Belongs to the 5'-nucleotidase family
G5S32_RS01525	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
G5S32_RS01525	COG1648	precorrin-2 dehydrogenase activity
G5S32_RS01530	COG0175	sulfate reduction
G5S32_RS01535	COG2895	sulfate adenylyltransferase (ATP) activity
G5S32_RS01540	COG0529	Catalyzes the synthesis of activated sulfate
G5S32_RS01580	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
G5S32_RS01585	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G5S32_RS01590	COG0729	surface antigen
G5S32_RS01600	COG2105	PFAM AIG2 family protein
G5S32_RS01610	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
G5S32_RS01615	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
G5S32_RS01620	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
G5S32_RS01625	COG0163	prenyltransferase activity
G5S32_RS01630	COG4143	(ABC) transporter
G5S32_RS01635	COG1178	ABC-type Fe3 transport system permease component
G5S32_RS01640	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
G5S32_RS01645	COG3028	Belongs to the UPF0307 family
G5S32_RS01650	COG0312	modulator of DNA gyrase
G5S32_RS01655	COG2239	Acts as a magnesium transporter
G5S32_RS01660	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
G5S32_RS01665	COG1660	Displays ATPase and GTPase activities
G5S32_RS01670	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
G5S32_RS01675	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
G5S32_RS01685	COG1137	ATPase activity
G5S32_RS01690	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
G5S32_RS01700	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
G5S32_RS01705	COG0517	IMP dehydrogenase activity
G5S32_RS01705	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
G5S32_RS01715	COG1127	ABC transporter
G5S32_RS01720	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G5S32_RS01725	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
G5S32_RS01730	COG2854	intermembrane phospholipid transfer
G5S32_RS01740	COG5007	Belongs to the BolA IbaG family
G5S32_RS01745	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
G5S32_RS01750	COG0204	Acyl-transferase
G5S32_RS01755	COG0251	oxidation-reduction process
G5S32_RS01760	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
G5S32_RS01775	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
G5S32_RS01790	COG0564	pseudouridine synthase activity
G5S32_RS01795	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
G5S32_RS01800	COG0525	valine-tRNA ligase activity
G5S32_RS01805	COG2927	DNA polymerase III (CHI subunit)
G5S32_RS01810	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
G5S32_RS01815	COG0795	lipopolysaccharide-transporting ATPase activity
G5S32_RS01820	COG0795	lipopolysaccharide-transporting ATPase activity
G5S32_RS01925	COG1073	alpha beta
G5S32_RS01930	COG1073	alpha beta
G5S32_RS01960	COG2084	Dehydrogenase
G5S32_RS01965	COG1278	Cold shock
G5S32_RS02005	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
G5S32_RS02055	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
G5S32_RS02060	COG0473	3-isopropylmalate dehydrogenase activity
G5S32_RS02080	COG0583	DNA-binding transcription factor activity
G5S32_RS02085	COG1022	Amp-dependent synthetase and ligase
G5S32_RS02090	COG0028	Belongs to the TPP enzyme family
G5S32_RS02100	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G5S32_RS02105	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
G5S32_RS02110	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
G5S32_RS02120	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
G5S32_RS02125	COG3079	Belongs to the UPF0149 family
G5S32_RS02130	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G5S32_RS02135	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G5S32_RS02155	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
G5S32_RS02165	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
G5S32_RS02170	COG1595	DNA-templated transcription, initiation
G5S32_RS02175	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
G5S32_RS02180	COG3026	antisigma factor binding
G5S32_RS02185	COG3086	response to oxidative stress
G5S32_RS02190	COG0481	GTPase activity
G5S32_RS02195	COG0681	Belongs to the peptidase S26 family
G5S32_RS02205	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
G5S32_RS02210	COG1381	Involved in DNA repair and RecF pathway recombination
G5S32_RS02215	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
G5S32_RS02230	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
G5S32_RS02235	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
G5S32_RS02240	COG3956	TIGRFAM MazG family protein
G5S32_RS02255	COG0617	tRNA 3'-terminal CCA addition
G5S32_RS02260	COG3267	Type II secretory pathway component ExeA
G5S32_RS02260	COG3409	Peptidoglycan-binding domain 1 protein
G5S32_RS02270	COG4991	sh3 domain protein
G5S32_RS02275	COG0306	phosphate transporter
G5S32_RS02280	COG1392	Phosphate transport regulator
G5S32_RS02285	COG3025	triphosphatase activity
G5S32_RS02290	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
G5S32_RS02300	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
G5S32_RS02310	COG1538	Outer membrane efflux protein
G5S32_RS02315	COG0494	nUDIX hydrolase
G5S32_RS02320	COG3151	Protein conserved in bacteria
G5S32_RS02330	COG3150	esterase
G5S32_RS02345	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
G5S32_RS02350	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
G5S32_RS02355	COG0237	dephospho-CoA kinase activity
G5S32_RS02365	COG1459	type II secretion system
G5S32_RS02370	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
G5S32_RS02390	COG0716	FMN binding
G5S32_RS02395	COG4974	Belongs to the 'phage' integrase family
G5S32_RS02400	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
G5S32_RS02405	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
G5S32_RS02410	COG2186	Transcriptional regulator
G5S32_RS02415	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
G5S32_RS02420	COG0508	dehydrogenase complex catalyzes the overall conversion of
G5S32_RS02425	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G5S32_RS02440	COG0288	reversible hydration of carbon dioxide
G5S32_RS02445	COG1131	(ABC) transporter
G5S32_RS02450	COG0842	Transport permease protein
G5S32_RS02455	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
G5S32_RS02460	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
G5S32_RS02465	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
G5S32_RS02475	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
G5S32_RS02480	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
G5S32_RS02490	COG1643	Atp-dependent helicase
G5S32_RS02495	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G5S32_RS02500	COG1752	Esterase of the alpha-beta hydrolase superfamily
G5S32_RS02505	COG1049	propionate catabolic process, 2-methylcitrate cycle
G5S32_RS02515	COG0347	Belongs to the P(II) protein family
G5S32_RS02520	COG0004	ammonium transporteR
G5S32_RS02525	COG1840	ABC-type Fe3 transport system, periplasmic component
G5S32_RS02535	COG3842	ATPase activity
G5S32_RS02540	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G5S32_RS02555	COG2971	BadF BadG BcrA BcrD
G5S32_RS02565	COG4608	Belongs to the ABC transporter superfamily
G5S32_RS02570	COG0444	Belongs to the ABC transporter superfamily
G5S32_RS02585	COG0747	negative chemotaxis
G5S32_RS02590	COG2205	protein histidine kinase activity
G5S32_RS02590	COG0784	Response regulator, receiver
G5S32_RS02595	COG2813	Specifically methylates the guanine in position
G5S32_RS02600	COG0628	permease
G5S32_RS02615	COG0316	Belongs to the HesB IscA family
G5S32_RS02635	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
G5S32_RS02640	COG2027	D-alanyl-D-alanine carboxypeptidase
G5S32_RS02645	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
G5S32_RS02650	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
G5S32_RS02655	COG1534	Rna-binding protein
G5S32_RS02660	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
G5S32_RS02665	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
G5S32_RS02670	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
G5S32_RS02675	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G5S32_RS02680	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
G5S32_RS02695	COG0779	Required for maturation of 30S ribosomal subunits
G5S32_RS02700	COG0195	Participates in both transcription termination and antitermination
G5S32_RS02710	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
G5S32_RS02715	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
G5S32_RS02720	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
G5S32_RS02740	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
G5S32_RS02745	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
G5S32_RS02780	COG4964	Belongs to the GSP D family
G5S32_RS02835	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
G5S32_RS02845	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
G5S32_RS02850	COG2017	converts alpha-aldose to the beta-anomer
G5S32_RS02855	COG1609	Transcriptional regulator
G5S32_RS02870	COG0189	ligase activity
G5S32_RS02870	COG0569	domain protein
G5S32_RS02880	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
G5S32_RS02885	COG1283	sodium-dependent phosphate transmembrane transporter activity
G5S32_RS02890	COG0583	DNA-binding transcription factor activity
G5S32_RS02895	COG0640	Transcriptional regulator
G5S32_RS02900	COG0268	Binds directly to 16S ribosomal RNA
G5S32_RS02905	COG0728	peptidoglycan biosynthetic process
G5S32_RS02910	COG0196	riboflavin kinase activity
G5S32_RS02915	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
G5S32_RS02920	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
G5S32_RS02925	COG1047	Peptidyl-prolyl cis-trans
G5S32_RS02930	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
G5S32_RS02935	COG1966	Carbon starvation protein
G5S32_RS02950	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
G5S32_RS02955	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
G5S32_RS02965	COG3279	Response regulator of the LytR AlgR family
G5S32_RS02970	COG3275	phosphorelay sensor kinase activity
G5S32_RS02975	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
G5S32_RS02980	COG0287	Prephenate dehydrogenase
G5S32_RS02980	COG1605	Chorismate mutase
G5S32_RS02990	COG0488	(ABC) transporter
G5S32_RS03005	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
G5S32_RS03010	COG5001	Diguanylate cyclase
G5S32_RS03015	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
G5S32_RS03020	COG1605	Chorismate mutase
G5S32_RS03020	COG0077	Prephenate dehydratase
G5S32_RS03025	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
G5S32_RS03030	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
G5S32_RS03035	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G5S32_RS03040	COG0564	pseudouridine synthase activity
G5S32_RS03050	COG0542	response to heat
G5S32_RS03060	COG0590	tRNA wobble adenosine to inosine editing
G5S32_RS03070	COG1116	anion transmembrane transporter activity
G5S32_RS03075	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G5S32_RS03140	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
G5S32_RS03155	COG0745	RESPONSE REGULATOR receiver
G5S32_RS03160	COG5002	protein histidine kinase activity
G5S32_RS03170	COG0248	Ppx GppA phosphatase
G5S32_RS03175	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
G5S32_RS03185	COG0581	inorganic phosphate transmembrane transporter activity
G5S32_RS03190	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
G5S32_RS03195	COG0704	Plays a role in the regulation of phosphate uptake
G5S32_RS03200	COG3142	Participates in the control of copper homeostasis
G5S32_RS03205	COG0450	alkyl hydroperoxide reductase
G5S32_RS03210	COG0583	DNA-binding transcription factor activity
G5S32_RS03215	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
G5S32_RS03230	COG3706	GGDEF domain
G5S32_RS03235	COG0840	transmembrane signaling receptor activity
G5S32_RS03240	COG0517	IMP dehydrogenase activity
G5S32_RS03245	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
G5S32_RS03255	COG1862	Preprotein translocase
G5S32_RS03260	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
G5S32_RS03265	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
G5S32_RS03270	COG1335	isochorismatase
G5S32_RS03275	COG0483	inositol monophosphate 1-phosphatase activity
G5S32_RS03280	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
G5S32_RS03285	COG1959	2 iron, 2 sulfur cluster binding
G5S32_RS03290	COG1104	cysteine desulfurase activity
G5S32_RS03295	COG0822	iron-sulfur transferase activity
G5S32_RS03300	COG0316	Belongs to the HesB IscA family
G5S32_RS03310	COG0443	Heat shock 70 kDa protein
G5S32_RS03315	COG0633	Ferredoxin
G5S32_RS03320	COG2975	iron-sulfur cluster assembly
G5S32_RS03325	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
G5S32_RS03345	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
G5S32_RS03350	COG0124	histidyl-tRNA synthetase
G5S32_RS03355	COG2976	Protein conserved in bacteria
G5S32_RS03360	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G5S32_RS03365	COG1160	GTP binding
G5S32_RS03395	COG0516	GMP reductase activity
G5S32_RS03395	COG0517	IMP dehydrogenase activity
G5S32_RS03405	COG1584	GPR1 FUN34 yaaH family protein
G5S32_RS03415	COG1115	amino acid carrier protein
G5S32_RS03425	COG0583	DNA-binding transcription factor activity
G5S32_RS03500	COG2003	Belongs to the UPF0758 family
G5S32_RS03505	COG0582	viral genome integration into host DNA
G5S32_RS03520	COG2867	negative regulation of translational initiation
G5S32_RS03525	COG2914	Belongs to the UPF0125 (RnfH) family
G5S32_RS03530	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G5S32_RS03535	COG0497	DNA recombination
G5S32_RS03545	COG0251	oxidation-reduction process
G5S32_RS03550	COG0814	amino acid
G5S32_RS03560	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
G5S32_RS03565	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
G5S32_RS03570	COG0443	Heat shock 70 kDa protein
G5S32_RS03575	COG0484	heat shock protein binding
G5S32_RS03585	COG4968	Prepilin-type N-terminal cleavage methylation domain
G5S32_RS03610	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
G5S32_RS03615	COG0583	DNA-binding transcription factor activity
G5S32_RS03620	COG0590	tRNA wobble adenosine to inosine editing
G5S32_RS03625	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
G5S32_RS03650	COG0442	prolyl-tRNA aminoacylation
G5S32_RS03655	COG1720	tRNA m6t6A37 methyltransferase activity
G5S32_RS03660	COG0257	Belongs to the bacterial ribosomal protein bL36 family
G5S32_RS03665	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
G5S32_RS03695	COG3098	single-species biofilm formation
G5S32_RS03700	COG0564	pseudouridine synthase activity
G5S32_RS03705	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
G5S32_RS03710	COG0142	geranyltranstransferase activity
G5S32_RS03715	COG1722	exodeoxyribonuclease VII activity
G5S32_RS03720	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
G5S32_RS03730	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
G5S32_RS03730	COG0301	tRNA thio-modification
G5S32_RS03735	COG0583	DNA-binding transcription factor activity
G5S32_RS03745	COG2363	Small membrane protein
G5S32_RS03755	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
G5S32_RS03760	COG1611	Belongs to the LOG family
G5S32_RS03785	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
G5S32_RS03790	COG1464	Belongs to the NlpA lipoprotein family
G5S32_RS03795	COG2011	ABC-type metal ion transport system permease component
G5S32_RS03800	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
G5S32_RS03805	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
G5S32_RS03815	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G5S32_RS03815	COG1263	PTS System
G5S32_RS03820	COG0366	Alpha amylase catalytic
G5S32_RS03850	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G5S32_RS03860	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
G5S32_RS03870	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
G5S32_RS03880	COG2921	Belongs to the UPF0250 family
G5S32_RS03885	COG1686	Belongs to the peptidase S11 family
G5S32_RS03890	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
G5S32_RS03895	COG0772	Belongs to the SEDS family
G5S32_RS03900	COG0768	penicillin binding
G5S32_RS03905	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
G5S32_RS03910	COG0799	negative regulation of ribosome biogenesis
G5S32_RS03915	COG1466	dna polymerase III delta subunit
G5S32_RS03920	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
G5S32_RS03930	COG2888	peptidyl-tyrosine sulfation
G5S32_RS03935	COG0815	Transfers the fatty acyl group on membrane lipoproteins
G5S32_RS03940	COG4535	Mg2 and Co2 transporter CorC
G5S32_RS03945	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
G5S32_RS03950	COG1702	phosphate starvation-inducible protein PhoH
G5S32_RS03955	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
G5S32_RS03960	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G5S32_RS03965	COG2190	(PTS) system
G5S32_RS03970	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
G5S32_RS03975	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
G5S32_RS03980	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
G5S32_RS03985	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
G5S32_RS03990	COG3115	cell septum assembly
G5S32_RS04010	COG0789	Transcriptional regulator
G5S32_RS04020	COG0330	HflC and HflK could
G5S32_RS04025	COG3118	belongs to the thioredoxin family
G5S32_RS04030	COG0300	oxidoreductase activity
G5S32_RS04035	COG1090	epimerase
G5S32_RS04060	COG0622	Phosphoesterase
G5S32_RS04075	COG3710	Transcriptional regulator
G5S32_RS04080	COG0326	Molecular chaperone. Has ATPase activity
G5S32_RS04090	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
G5S32_RS04095	COG3104	oligopeptide transport
G5S32_RS04105	COG0367	asparagine synthase
G5S32_RS04110	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
G5S32_RS04110	COG4651	solute:proton antiporter activity
G5S32_RS04115	COG1846	Transcriptional regulator
G5S32_RS04115	COG1940	carbohydrate kinase activity
G5S32_RS04120	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
G5S32_RS04125	COG1263	PTS System
G5S32_RS04125	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G5S32_RS04125	COG2190	(PTS) system
G5S32_RS04140	COG0101	tRNA pseudouridine synthase activity
G5S32_RS04145	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
G5S32_RS04150	COG0285	dihydrofolate synthase activity
G5S32_RS04155	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
G5S32_RS04160	COG1286	toxin biosynthetic process
G5S32_RS04165	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
G5S32_RS04170	COG2056	Na+-H+ antiporter family
G5S32_RS04175	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
G5S32_RS04185	COG0346	lactoylglutathione lyase activity
G5S32_RS04190	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
G5S32_RS04195	COG4660	Part of a membrane complex involved in electron transport
G5S32_RS04205	COG4658	electron transport chain
G5S32_RS04210	COG4656	Part of a membrane complex involved in electron transport
G5S32_RS04220	COG4657	Part of a membrane complex involved in electron transport
G5S32_RS04225	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G5S32_RS04225	COG1263	PTS System
G5S32_RS04230	COG3005	denitrification pathway
G5S32_RS04235	COG0243	molybdopterin cofactor binding
G5S32_RS04245	COG0556	nucleotide-excision repair
G5S32_RS04250	COG2204	response regulator
G5S32_RS04255	COG2198	Histidine kinase
G5S32_RS04260	COG0391	Required for morphogenesis under gluconeogenic growth conditions
G5S32_RS04265	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
G5S32_RS04270	COG0521	Mo-molybdopterin cofactor biosynthetic process
G5S32_RS04280	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
G5S32_RS04285	COG0314	molybdopterin synthase activity
G5S32_RS04290	COG0617	tRNA 3'-terminal CCA addition
G5S32_RS04290	COG0517	IMP dehydrogenase activity
G5S32_RS04290	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
G5S32_RS04305	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G5S32_RS04305	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G5S32_RS04315	COG0572	uridine kinase
G5S32_RS04320	COG2982	Protein involved in outer membrane biogenesis
G5S32_RS04325	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
G5S32_RS04330	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
G5S32_RS04335	COG2067	long-chain fatty acid transport protein
G5S32_RS04355	COG0183	Belongs to the thiolase family
G5S32_RS04360	COG1250	3-hydroxyacyl-CoA dehydrogenase
G5S32_RS04360	COG1024	Enoyl-CoA hydratase
G5S32_RS04365	COG0778	Nitroreductase
G5S32_RS04375	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
G5S32_RS04395	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G5S32_RS04415	COG3300	MHYT domain
G5S32_RS04415	COG5001	Diguanylate cyclase
G5S32_RS04420	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G5S32_RS04425	COG2095	MarC family integral membrane protein
G5S32_RS04430	COG1454	alcohol dehydrogenase
G5S32_RS04430	COG1012	belongs to the aldehyde dehydrogenase family
G5S32_RS04455	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G5S32_RS04455	COG3153	acetyltransferase
G5S32_RS04465	COG0745	RESPONSE REGULATOR receiver
G5S32_RS04470	COG2205	protein histidine kinase activity
G5S32_RS04480	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
G5S32_RS04485	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
G5S32_RS04490	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
G5S32_RS04495	COG2204	response regulator
G5S32_RS04505	COG0544	peptidyl-prolyl cis-trans isomerase activity
G5S32_RS04515	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
G5S32_RS04520	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
G5S32_RS04525	COG0776	regulation of translation
G5S32_RS04530	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
G5S32_RS04535	COG1555	photosystem II stabilization
G5S32_RS04540	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
G5S32_RS04545	COG0539	negative regulation of cytoplasmic translation
G5S32_RS04555	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
G5S32_RS04560	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
G5S32_RS04580	COG0583	DNA-binding transcription factor activity
G5S32_RS04590	COG0686	Belongs to the AlaDH PNT family
G5S32_RS04595	COG1522	sequence-specific DNA binding
G5S32_RS04600	COG1674	ftsk spoiiie
G5S32_RS04605	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
G5S32_RS04610	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
G5S32_RS04615	COG2186	Transcriptional regulator
G5S32_RS04630	COG0537	adenosine 5'-monophosphoramidase activity
G5S32_RS04660	COG1252	NADH dehydrogenase
G5S32_RS04675	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
G5S32_RS04685	COG4591	ABC-type transport system involved in lipoprotein release permease component
G5S32_RS04690	COG1136	(ABC) transporter
G5S32_RS04695	COG4591	ABC-type transport system involved in lipoprotein release permease component
G5S32_RS04705	COG2333	competence protein COMEC
G5S32_RS04705	COG0658	competence protein
G5S32_RS04710	COG1132	(ABC) transporter
G5S32_RS04715	COG1663	tetraacyldisaccharide 4'-kinase activity
G5S32_RS04725	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
G5S32_RS04730	COG2719	SpoVR family
G5S32_RS04735	COG2718	Belongs to the UPF0229 family
G5S32_RS04740	COG2766	serine protein kinase
G5S32_RS04750	COG3013	Belongs to the UPF0304 family
G5S32_RS04760	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
G5S32_RS04775	COG1882	Formate acetyltransferase
G5S32_RS04805	COG4160	amino acid transport
G5S32_RS04830	COG0730	response to heat
G5S32_RS04835	COG1199	ATP-dependent helicase activity
G5S32_RS04845	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
G5S32_RS04850	COG3012	SEC-C Motif Domain Protein
G5S32_RS04855	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
G5S32_RS04865	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
G5S32_RS04870	COG0215	cysteine-tRNA ligase activity
G5S32_RS04875	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
G5S32_RS04895	COG1294	oxidase, subunit
G5S32_RS04900	COG4890	Cyd operon protein YbgT
G5S32_RS04910	COG0824	Thioesterase
G5S32_RS04915	COG0811	peptide transport
G5S32_RS04935	COG2885	chlorophyll binding
G5S32_RS04940	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
G5S32_RS04945	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
G5S32_RS04975	COG0786	glutamate:sodium symporter activity
G5S32_RS04990	COG1126	abc transporter atp-binding protein
G5S32_RS04995	COG0765	amino acid transport
G5S32_RS05000	COG4597	amino acid ABC transporter
G5S32_RS05005	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G5S32_RS05030	COG5002	protein histidine kinase activity
G5S32_RS05035	COG0745	RESPONSE REGULATOR receiver
G5S32_RS05045	COG1960	acyl-CoA dehydrogenase activity
G5S32_RS05050	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
G5S32_RS05055	COG3273	potassium ion transport
G5S32_RS05055	COG2985	domain, Protein
G5S32_RS05060	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
G5S32_RS05070	COG1737	Transcriptional regulator
G5S32_RS05075	COG0076	glutamate decarboxylase activity
G5S32_RS05085	COG2431	L-lysine efflux transmembrane transporter activity
G5S32_RS05095	COG3070	regulator of competence-specific genes
G5S32_RS05110	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G5S32_RS05110	COG4191	Histidine kinase
G5S32_RS05120	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
G5S32_RS05125	COG1032	radical SAM domain protein
G5S32_RS05130	COG0582	viral genome integration into host DNA
G5S32_RS05155	COG5532	Uncharacterized conserved protein (DUF2303)
G5S32_RS05205	COG4626	Terminase
G5S32_RS05205	COG1802	Transcriptional regulator
G5S32_RS05220	COG1403	HNH endonuclease
G5S32_RS05285	COG3772	lysozyme
G5S32_RS05315	COG1030	water channel activity
G5S32_RS05405	COG2184	nucleotidyltransferase activity
G5S32_RS05425	COG0583	DNA-binding transcription factor activity
G5S32_RS05445	COG1684	flagellar biosynthetic protein fliR
G5S32_RS05450	COG1987	bacterial-type flagellum assembly
G5S32_RS05460	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
G5S32_RS05465	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
G5S32_RS05470	COG1815	bacterial-type flagellum-dependent cell motility
G5S32_RS05475	COG1558	bacterial-type flagellum-dependent cell motility
G5S32_RS05480	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
G5S32_RS05485	COG1749	Flagellar hook protein flgE
G5S32_RS05490	COG4786	Flagellar basal body rod
G5S32_RS05495	COG4786	Flagellar basal body rod
G5S32_RS05500	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
G5S32_RS05505	COG1706	bacterial-type flagellum-dependent cell motility
G5S32_RS05530	COG1677	Flagellar hook-basal body complex protein FliE
G5S32_RS05540	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
G5S32_RS05580	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
G5S32_RS05590	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
G5S32_RS05620	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
G5S32_RS05625	COG1360	Flagellar Motor Protein
G5S32_RS05640	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
G5S32_RS05650	COG2350	Protein conserved in bacteria
G5S32_RS05665	COG1301	dicarboxylic acid transport
G5S32_RS05675	COG0133	tryptophan synthase activity
G5S32_RS05680	COG0134	indole-3-glycerol-phosphate synthase activity
G5S32_RS05680	COG0135	phosphoribosylanthranilate isomerase activity
G5S32_RS05685	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
G5S32_RS05690	COG0512	Glutamine amidotransferase of anthranilate synthase
G5S32_RS05695	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
G5S32_RS05705	COG0613	PHP domain protein
G5S32_RS05710	COG0009	L-threonylcarbamoyladenylate synthase
G5S32_RS05715	COG1187	pseudouridine synthase activity
G5S32_RS05720	COG1253	flavin adenine dinucleotide binding
G5S32_RS05755	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
G5S32_RS05760	COG4988	ABC transporter
G5S32_RS05765	COG0492	ferredoxin-NADP+ reductase activity
G5S32_RS05780	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
G5S32_RS05790	COG2949	membrane
G5S32_RS05800	COG0281	malic enzyme
G5S32_RS05815	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
G5S32_RS05825	COG2199	diguanylate cyclase activity
G5S32_RS05830	COG3706	GGDEF domain
G5S32_RS05845	COG2885	chlorophyll binding
G5S32_RS05860	COG0277	FAD linked oxidase domain protein
G5S32_RS05860	COG0247	lactate metabolic process
G5S32_RS05875	COG2986	histidine ammonia-lyase
G5S32_RS05885	COG1228	amidohydrolase
G5S32_RS05905	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
G5S32_RS05915	COG0417	DNA replication proofreading
G5S32_RS05920	COG2197	response regulator
G5S32_RS05925	COG0322	excinuclease ABC activity
G5S32_RS05955	COG2133	pyrroloquinoline quinone binding
G5S32_RS05960	COG3706	GGDEF domain
G5S32_RS05970	COG0072	phenylalanine-tRNA ligase activity
G5S32_RS05970	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G5S32_RS05985	COG0500	methyltransferase
G5S32_RS06005	COG5001	Diguanylate cyclase
G5S32_RS06005	COG3300	MHYT domain
G5S32_RS06010	COG0295	cytidine deaminase activity
G5S32_RS06015	COG1346	cytolysis
G5S32_RS06020	COG1380	Effector of murein hydrolase LrgA
G5S32_RS06025	COG2925	Exonuclease
G5S32_RS06030	COG0702	epimerase
G5S32_RS06040	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
G5S32_RS06050	COG2988	succinylglutamate desuccinylase activity
G5S32_RS06055	COG4139	cobalamin transport
G5S32_RS06060	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
G5S32_RS06100	COG0583	DNA-binding transcription factor activity
G5S32_RS06110	COG1451	nucleotide metabolic process
G5S32_RS06150	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G5S32_RS06165	COG3290	protein histidine kinase activity
G5S32_RS06170	COG4565	transcriptional regulatory protein
G5S32_RS06210	COG2201	protein-glutamate methylesterase activity
G5S32_RS06215	COG3706	GGDEF domain
G5S32_RS06230	COG1984	allophanate hydrolase subunit 2
G5S32_RS06235	COG2203	Gaf domain
G5S32_RS06235	COG3706	GGDEF domain
G5S32_RS06235	COG5001	Diguanylate cyclase
G5S32_RS06235	COG4251	negative regulation of phosphorylation
G5S32_RS06250	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
G5S32_RS06260	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
G5S32_RS06280	COG0800	Aldolase
G5S32_RS06285	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G5S32_RS06295	COG1028	Short-chain dehydrogenase reductase Sdr
G5S32_RS06300	COG1414	Transcriptional regulator
G5S32_RS06305	COG1785	Belongs to the alkaline phosphatase family
G5S32_RS06330	COG0154	amidase activity
G5S32_RS06340	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
G5S32_RS06355	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
G5S32_RS06360	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
G5S32_RS06380	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
G5S32_RS06395	COG0583	DNA-binding transcription factor activity
G5S32_RS06405	COG1028	Short-chain dehydrogenase reductase Sdr
G5S32_RS06410	COG0183	Belongs to the thiolase family
G5S32_RS06435	COG0402	S-adenosylhomocysteine deaminase activity
G5S32_RS06480	COG1129	ABC transporter
G5S32_RS06505	COG3842	ATPase activity
G5S32_RS06515	COG1349	DNA-binding transcription factor activity
G5S32_RS06530	COG2851	Citrate transporter
G5S32_RS06555	COG0183	Belongs to the thiolase family
G5S32_RS06575	COG0596	Alpha beta hydrolase
G5S32_RS06595	COG2084	Dehydrogenase
G5S32_RS06610	COG0604	alcohol dehydrogenase
G5S32_RS06630	COG0477	Major facilitator Superfamily
G5S32_RS06635	COG1902	pentaerythritol trinitrate reductase activity
G5S32_RS06650	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
G5S32_RS06655	COG2207	Transcriptional regulator
G5S32_RS06670	COG0531	amino acid
G5S32_RS06675	COG2957	Belongs to the agmatine deiminase family
G5S32_RS06685	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G5S32_RS06690	COG3842	ATPase activity
G5S32_RS06700	COG3665	Urea carboxylase-associated protein
G5S32_RS06705	COG0439	Biotin carboxylase
G5S32_RS06715	COG3300	MHYT domain
G5S32_RS06715	COG5001	Diguanylate cyclase
G5S32_RS06720	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
G5S32_RS06725	COG3706	GGDEF domain
G5S32_RS06730	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
G5S32_RS06735	COG1254	Belongs to the acylphosphatase family
G5S32_RS06740	COG2920	part of a sulfur-relay system
G5S32_RS06745	COG0670	Belongs to the BI1 family
G5S32_RS06750	COG1126	abc transporter atp-binding protein
G5S32_RS06755	COG0765	amino acid transport
G5S32_RS06760	COG4597	amino acid ABC transporter
G5S32_RS06765	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G5S32_RS06775	COG0561	phosphatase activity
G5S32_RS06780	COG0602	queuosine metabolic process
G5S32_RS06790	COG3706	GGDEF domain
G5S32_RS06815	COG0443	Heat shock 70 kDa protein
G5S32_RS06840	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
G5S32_RS06845	COG1643	Atp-dependent helicase
G5S32_RS06860	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
G5S32_RS06880	COG1115	amino acid carrier protein
G5S32_RS06895	COG1666	GTP binding
G5S32_RS06900	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
G5S32_RS06920	COG2996	Protein conserved in bacteria
G5S32_RS06930	COG3008	intermembrane lipid transfer
G5S32_RS06935	COG2995	paraquat-inducible protein a
G5S32_RS06940	COG1132	(ABC) transporter
G5S32_RS06945	COG1956	GAF domain-containing protein
G5S32_RS06950	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
G5S32_RS06955	COG0793	Belongs to the peptidase S41A family
G5S32_RS06965	COG0308	aminopeptidase N
G5S32_RS06975	COG2902	Dehydrogenase
G5S32_RS06980	COG0167	dihydroorotate dehydrogenase activity
G5S32_RS06990	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
G5S32_RS06990	COG0116	Belongs to the methyltransferase superfamily
G5S32_RS07000	COG0488	(ABC) transporter
G5S32_RS07015	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
G5S32_RS07020	COG1067	ATP-dependent peptidase activity
G5S32_RS07025	COG3120	sequence-specific DNA binding
G5S32_RS07130	COG3278	Belongs to the heme-copper respiratory oxidase family
G5S32_RS07145	COG2010	Cytochrome c
G5S32_RS07155	COG2217	Heavy metal translocating P-type atpase
G5S32_RS07170	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G5S32_RS07175	COG0589	response to stress
G5S32_RS07200	COG3842	ATPase activity
G5S32_RS07205	COG1176	ABC-type spermidine putrescine transport system, permease component I
G5S32_RS07210	COG1177	transmembrane transport
G5S32_RS07225	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
G5S32_RS07230	COG0004	ammonium transporteR
G5S32_RS07245	COG0437	4 iron, 4 sulfur cluster binding
G5S32_RS07250	COG3383	formate dehydrogenase (NAD+) activity
G5S32_RS07250	COG0243	molybdopterin cofactor binding
G5S32_RS07280	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
G5S32_RS07295	COG3852	Histidine kinase
G5S32_RS07300	COG2204	response regulator
G5S32_RS07310	COG4662	Binding-protein-dependent transport system inner membrane component
G5S32_RS07320	COG0746	molybdenum cofactor guanylyltransferase activity
G5S32_RS07325	COG0303	'Molybdopterin
G5S32_RS07335	COG1940	carbohydrate kinase activity
G5S32_RS07355	COG0791	NLP P60 protein
G5S32_RS07365	COG3001	Fructosamine kinase
G5S32_RS07375	COG0307	riboflavin synthase, alpha
G5S32_RS07385	COG4667	esterase of the alpha-beta hydrolase superfamily
G5S32_RS07405	COG0848	biopolymer transport protein
G5S32_RS07410	COG0811	peptide transport
G5S32_RS07415	COG0811	peptide transport
G5S32_RS07425	COG0039	L-malate dehydrogenase activity
G5S32_RS07440	COG0395	ABC-type sugar transport system, permease component
G5S32_RS07445	COG3842	ATPase activity
G5S32_RS07450	COG1349	DNA-binding transcription factor activity
G5S32_RS07455	COG0584	glycerophosphoryl diester phosphodiesterase
G5S32_RS07470	COG2731	YhcH YjgK YiaL family protein
G5S32_RS07475	COG0783	Belongs to the Dps family
G5S32_RS07480	COG2195	Cleaves the N-terminal amino acid of tripeptides
G5S32_RS07500	COG1566	PFAM secretion protein HlyD family protein
G5S32_RS07515	COG2828	Protein conserved in bacteria
G5S32_RS07520	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
G5S32_RS07525	COG0372	Belongs to the citrate synthase family
G5S32_RS07530	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
G5S32_RS07555	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
G5S32_RS07630	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
G5S32_RS07715	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
G5S32_RS07725	COG1012	belongs to the aldehyde dehydrogenase family
G5S32_RS07735	COG4656	Part of a membrane complex involved in electron transport
G5S32_RS07765	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
G5S32_RS07775	COG0384	phenazine biosynthesis protein PhzF
G5S32_RS07805	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G5S32_RS07845	COG0653	protein targeting
G5S32_RS07875	COG3250	beta-galactosidase activity
G5S32_RS07880	COG0406	alpha-ribazole phosphatase activity
G5S32_RS07905	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
G5S32_RS07910	COG2194	sulfuric ester hydrolase activity
G5S32_RS07920	COG1129	ABC transporter
G5S32_RS07945	COG3119	arylsulfatase activity
G5S32_RS07955	COG3437	response regulator, receiver
G5S32_RS07960	COG0494	nUDIX hydrolase
G5S32_RS07990	COG0471	metal ion transport
G5S32_RS08005	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G5S32_RS08015	COG3768	UPF0283 membrane protein
G5S32_RS08020	COG3106	COG3106 Predicted ATPase
G5S32_RS08035	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
G5S32_RS08040	COG0494	nUDIX hydrolase
G5S32_RS08045	COG0814	amino acid
G5S32_RS08050	COG1760	l-serine dehydratase
G5S32_RS08055	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G5S32_RS08060	COG1136	(ABC) transporter
G5S32_RS08060	COG0577	efflux transmembrane transporter activity
G5S32_RS08065	COG1538	Outer membrane efflux protein
G5S32_RS08070	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
G5S32_RS08075	COG0583	DNA-binding transcription factor activity
G5S32_RS08080	COG0243	molybdopterin cofactor binding
G5S32_RS08085	COG0720	synthase
G5S32_RS08090	COG0840	transmembrane signaling receptor activity
G5S32_RS08095	COG0017	Asparaginyl-tRNA synthetase
G5S32_RS08105	COG1448	Aminotransferase
G5S32_RS08120	COG2176	DNA-directed DNA polymerase activity
G5S32_RS08125	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
G5S32_RS08130	COG1846	Transcriptional regulator
G5S32_RS08155	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
G5S32_RS08170	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G5S32_RS08175	COG3108	Peptidase M15
G5S32_RS08205	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
G5S32_RS08220	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
G5S32_RS08225	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
G5S32_RS08265	COG1748	Saccharopine dehydrogenase
G5S32_RS08285	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
G5S32_RS08300	COG1136	(ABC) transporter
G5S32_RS08305	COG0534	Mate efflux family protein
G5S32_RS08310	COG0702	epimerase
G5S32_RS08320	COG2814	Major facilitator Superfamily
G5S32_RS08325	COG1187	pseudouridine synthase activity
G5S32_RS08330	COG1061	Type III restriction enzyme res subunit
G5S32_RS08340	COG0745	RESPONSE REGULATOR receiver
G5S32_RS08345	COG5002	protein histidine kinase activity
G5S32_RS08365	COG2308	Evidence 4 Homologs of previously reported genes of
G5S32_RS08380	COG2308	Evidence 4 Homologs of previously reported genes of
G5S32_RS08380	COG2307	Protein conserved in bacteria
G5S32_RS08405	COG5492	domain, Protein
G5S32_RS08415	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G5S32_RS08420	COG0697	spore germination
G5S32_RS08450	COG1131	(ABC) transporter
G5S32_RS08455	COG0842	Transport permease protein
G5S32_RS08465	COG3313	Fe-S protein
G5S32_RS08470	COG1869	D-ribose catabolic process
G5S32_RS08475	COG1129	ABC transporter
G5S32_RS08480	COG1172	Belongs to the binding-protein-dependent transport system permease family
G5S32_RS08485	COG1879	ABC-type sugar transport system periplasmic component
G5S32_RS08490	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G5S32_RS08510	COG0564	pseudouridine synthase activity
G5S32_RS08515	COG0733	neurotransmitter:sodium symporter activity
G5S32_RS08525	COG0626	cystathionine gamma-synthase activity
G5S32_RS08530	COG0519	Catalyzes the synthesis of GMP from XMP
G5S32_RS08545	COG1842	Phage shock protein A
G5S32_RS08550	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
G5S32_RS08560	COG4168	peptide transport system, permease
G5S32_RS08565	COG4171	peptide transport system, permease
G5S32_RS08575	COG4172	Belongs to the ABC transporter superfamily
G5S32_RS08585	COG1227	inorganic diphosphatase activity
G5S32_RS08590	COG0390	transport system, permease component
G5S32_RS08595	COG2116	formate transmembrane transporter activity
G5S32_RS08620	COG3051	citrate lyase alpha subunit
G5S32_RS08625	COG2301	Belongs to the HpcH HpaI aldolase family
G5S32_RS08635	COG4565	transcriptional regulatory protein
G5S32_RS08640	COG3290	protein histidine kinase activity
G5S32_RS08645	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
G5S32_RS08655	COG3630	sodium ion export across plasma membrane
G5S32_RS08665	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
G5S32_RS08685	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G5S32_RS08690	COG1434	Gram-negative-bacterium-type cell wall biogenesis
G5S32_RS08695	COG1435	thymidine kinase activity
G5S32_RS08705	COG1801	Protein of unknown function DUF72
G5S32_RS08710	COG4106	trans-aconitate 2-methyltransferase activity
G5S32_RS08715	COG0500	methyltransferase
G5S32_RS08720	COG4067	protein conserved in archaea
G5S32_RS08720	COG0189	ligase activity
G5S32_RS08735	COG0494	nUDIX hydrolase
G5S32_RS08745	COG1012	belongs to the aldehyde dehydrogenase family
G5S32_RS08750	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G5S32_RS08765	COG4215	(ABC) transporter
G5S32_RS08800	COG1802	Transcriptional regulator
G5S32_RS08840	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
G5S32_RS08845	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
G5S32_RS08855	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
G5S32_RS08860	COG1434	Gram-negative-bacterium-type cell wall biogenesis
G5S32_RS08870	COG1609	Transcriptional regulator
G5S32_RS08875	COG3070	regulator of competence-specific genes
G5S32_RS08880	COG0398	Pfam SNARE associated Golgi protein
G5S32_RS08890	COG0297	glycogen (starch) synthase activity
G5S32_RS08895	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
G5S32_RS08900	COG3385	transposase activity
G5S32_RS08905	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
G5S32_RS08925	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
G5S32_RS08930	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
G5S32_RS08935	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
G5S32_RS08940	COG0542	response to heat
G5S32_RS08945	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
G5S32_RS08950	COG1278	Cold shock
G5S32_RS08960	COG1187	pseudouridine synthase activity
G5S32_RS08970	COG0351	phosphomethylpyrimidine kinase
G5S32_RS08980	COG0140	phosphoribosyl-ATP diphosphatase activity
G5S32_RS08980	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
G5S32_RS08990	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
G5S32_RS08995	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
G5S32_RS09000	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
G5S32_RS09000	COG0131	Imidazoleglycerol-phosphate dehydratase
G5S32_RS09005	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
G5S32_RS09010	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
G5S32_RS09015	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
G5S32_RS09020	COG1757	Na H antiporter
G5S32_RS09025	COG2916	Histone family protein nucleoid-structuring protein H-NS
G5S32_RS09030	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G5S32_RS09035	COG0482	sulfurtransferase activity
G5S32_RS09040	COG2915	High frequency lysogenization protein hflD homolog
G5S32_RS09045	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
G5S32_RS09065	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G5S32_RS09080	COG0300	oxidoreductase activity
G5S32_RS09090	COG0501	Belongs to the peptidase M48B family
G5S32_RS09100	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
G5S32_RS09110	COG0156	8-amino-7-oxononanoate synthase activity
G5S32_RS09115	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
G5S32_RS09125	COG2146	nitrite reductase [NAD(P)H] activity
G5S32_RS09125	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G5S32_RS09130	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G5S32_RS09130	COG2146	nitrite reductase [NAD(P)H] activity
G5S32_RS09135	COG1116	anion transmembrane transporter activity
G5S32_RS09140	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G5S32_RS09145	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G5S32_RS09145	COG1116	anion transmembrane transporter activity
G5S32_RS09160	COG1648	precorrin-2 dehydrogenase activity
G5S32_RS09160	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
G5S32_RS09165	COG0243	molybdopterin cofactor binding
G5S32_RS09170	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
G5S32_RS09175	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
G5S32_RS09180	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
G5S32_RS09195	COG3706	GGDEF domain
G5S32_RS09205	COG4120	Belongs to the binding-protein-dependent transport system permease family
G5S32_RS09215	COG3092	negative regulation of chromosome organization
G5S32_RS09220	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
G5S32_RS09225	COG0857	belongs to the CobB CobQ family
G5S32_RS09225	COG0280	phosphate acetyltransferase
G5S32_RS09230	COG0435	Glutathione S-transferase
G5S32_RS09240	COG0444	Belongs to the ABC transporter superfamily
G5S32_RS09245	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G5S32_RS09250	COG0601	transmembrane transport
G5S32_RS09260	COG0644	oxidoreductase
G5S32_RS09285	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G5S32_RS09290	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G5S32_RS09315	COG2986	histidine ammonia-lyase
G5S32_RS09340	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
G5S32_RS09350	COG1028	Short-chain dehydrogenase reductase Sdr
G5S32_RS09360	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G5S32_RS09365	COG1621	beta-fructofuranosidase activity
G5S32_RS09375	COG1263	PTS System
G5S32_RS09375	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G5S32_RS09385	COG0642	Histidine kinase
G5S32_RS09390	COG0745	RESPONSE REGULATOR receiver
G5S32_RS09400	COG4977	sequence-specific DNA binding
G5S32_RS09400	COG1917	Cupin 2, conserved barrel domain protein
G5S32_RS09405	COG2814	Major facilitator Superfamily
G5S32_RS09410	COG1566	PFAM secretion protein HlyD family protein
G5S32_RS09415	COG1538	Outer membrane efflux protein
G5S32_RS09420	COG1309	transcriptional regulator
G5S32_RS09425	COG1741	Belongs to the pirin family
G5S32_RS09430	COG2723	6-phospho-beta-galactosidase activity
G5S32_RS09435	COG1609	Transcriptional regulator
G5S32_RS09445	COG0247	lactate metabolic process
G5S32_RS09450	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
G5S32_RS09455	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
G5S32_RS09460	COG2271	Major facilitator Superfamily
G5S32_RS09465	COG1349	DNA-binding transcription factor activity
G5S32_RS09470	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
G5S32_RS09475	COG0450	alkyl hydroperoxide reductase
G5S32_RS09480	COG3634	alkyl hydroperoxide reductase activity
G5S32_RS09495	COG2207	Transcriptional regulator
G5S32_RS09495	COG1917	Cupin 2, conserved barrel domain protein
G5S32_RS09505	COG0840	transmembrane signaling receptor activity
G5S32_RS09510	COG0840	transmembrane signaling receptor activity
G5S32_RS09535	COG1131	(ABC) transporter
G5S32_RS09565	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
G5S32_RS09570	COG1447	Phosphotransferase system cellobiose-specific component IIA
G5S32_RS09575	COG1609	Transcriptional regulator
G5S32_RS09580	COG2723	6-phospho-beta-galactosidase activity
G5S32_RS09585	COG2190	(PTS) system
G5S32_RS09585	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G5S32_RS09585	COG1263	PTS System
G5S32_RS09590	COG1609	Transcriptional regulator
G5S32_RS09595	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G5S32_RS09600	COG2723	6-phospho-beta-galactosidase activity
G5S32_RS09605	COG2190	(PTS) system
G5S32_RS09605	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G5S32_RS09605	COG1263	PTS System
G5S32_RS09610	COG2723	6-phospho-beta-galactosidase activity
G5S32_RS09620	COG2199	diguanylate cyclase activity
G5S32_RS09640	COG1946	Acyl-CoA thioesterase
G5S32_RS09645	COG1522	sequence-specific DNA binding
G5S32_RS09655	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
G5S32_RS09675	COG0477	Major facilitator Superfamily
G5S32_RS09680	COG2855	membrane
G5S32_RS09690	COG0318	PFAM AMP-dependent synthetase and ligase
G5S32_RS09700	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
G5S32_RS09705	COG0596	Alpha beta hydrolase
G5S32_RS09710	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
G5S32_RS09715	COG1169	isochorismate synthase
G5S32_RS09720	COG0436	Aminotransferase
G5S32_RS09725	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
G5S32_RS09735	COG0232	Belongs to the dGTPase family. Type 2 subfamily
G5S32_RS09755	COG0616	signal peptide processing
G5S32_RS09760	COG1028	Short-chain dehydrogenase reductase Sdr
G5S32_RS09780	COG0835	chemotaxis
G5S32_RS09780	COG0784	Response regulator, receiver
G5S32_RS09785	COG1940	carbohydrate kinase activity
G5S32_RS09790	COG0469	pyruvate kinase activity
G5S32_RS09795	COG4667	esterase of the alpha-beta hydrolase superfamily
G5S32_RS09805	COG0733	neurotransmitter:sodium symporter activity
G5S32_RS09825	COG1263	PTS System
G5S32_RS09825	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G5S32_RS09830	COG0084	hydrolase, TatD family'
G5S32_RS09835	COG0470	DNA polymerase III
G5S32_RS09840	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
G5S32_RS09845	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
G5S32_RS09850	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
G5S32_RS09855	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
G5S32_RS09875	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
G5S32_RS09885	COG0333	Belongs to the bacterial ribosomal protein bL32 family
G5S32_RS09890	COG1399	metal-binding, possibly nucleic acid-binding protein
G5S32_RS09895	COG0424	maF-like protein
G5S32_RS09900	COG0564	pseudouridine synthase activity
G5S32_RS09905	COG1530	ribonuclease E activity
G5S32_RS09910	COG0659	secondary active sulfate transmembrane transporter activity
G5S32_RS09930	COG3385	transposase activity
G5S32_RS09935	COG2951	lytic endotransglycosylase activity
G5S32_RS09940	COG3100	YcgL domain-containing protein
G5S32_RS09945	COG0850	regulation of cytokinetic process
G5S32_RS09950	COG2894	cell division
G5S32_RS09955	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
G5S32_RS09960	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
G5S32_RS09965	COG0318	PFAM AMP-dependent synthetase and ligase
G5S32_RS09970	COG0596	Alpha beta hydrolase
G5S32_RS09975	COG3065	identical protein binding
G5S32_RS09985	COG1214	PFAM Peptidase M22, glycoprotease
G5S32_RS09990	COG1199	ATP-dependent helicase activity
G5S32_RS10000	COG0788	formyltetrahydrofolate deformylase activity
G5S32_RS10005	COG0446	pyridine nucleotide-disulphide oxidoreductase
G5S32_RS10005	COG1902	pentaerythritol trinitrate reductase activity
G5S32_RS10010	COG0616	signal peptide processing
G5S32_RS10015	COG0252	asparaginase activity
G5S32_RS10020	COG3139	Protein of unknown function (DUF1315)
G5S32_RS10030	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G5S32_RS10035	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
G5S32_RS10040	COG0676	glucose-6-phosphate 1-epimerase activity
G5S32_RS10045	COG0840	transmembrane signaling receptor activity
G5S32_RS10050	COG2226	methyltransferase
G5S32_RS10070	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
G5S32_RS10075	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
G5S32_RS10085	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
G5S32_RS10090	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
G5S32_RS10095	COG2832	Protein of unknown function (DUF454)
G5S32_RS10100	COG0745	RESPONSE REGULATOR receiver
G5S32_RS10105	COG0583	DNA-binding transcription factor activity
G5S32_RS10110	COG3081	Nucleoid-associated protein
G5S32_RS10115	COG3082	Protein of unknown function (DUF1414)
G5S32_RS10120	COG3083	sulfuric ester hydrolase activity
G5S32_RS10165	COG1113	amino acid transport
G5S32_RS10170	COG1522	sequence-specific DNA binding
G5S32_RS10180	COG1448	Aminotransferase
G5S32_RS10185	COG0123	including yeast histone deacetylase and acetoin utilization protein
G5S32_RS10195	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
G5S32_RS10200	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
G5S32_RS10220	COG2853	Lipoprotein
G5S32_RS10225	COG4235	cytochrome complex assembly
G5S32_RS10230	COG4235	cytochrome complex assembly
G5S32_RS10230	COG3088	subunit of a heme lyase
G5S32_RS10235	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G5S32_RS10240	COG1138	Cytochrome C-type biogenesis protein
G5S32_RS10245	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
G5S32_RS10250	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
G5S32_RS10255	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
G5S32_RS10260	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
G5S32_RS10265	COG4133	protoheme IX ABC transporter activity
G5S32_RS10275	COG0835	chemotaxis
G5S32_RS10285	COG1192	Involved in chromosome partitioning
G5S32_RS10290	COG2201	protein-glutamate methylesterase activity
G5S32_RS10295	COG0643	Histidine kinase
G5S32_RS10295	COG0784	Response regulator, receiver
G5S32_RS10295	COG2198	Histidine kinase
G5S32_RS10300	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
G5S32_RS10330	COG2062	phosphohistidine phosphatase, SixA
G5S32_RS10340	COG3102	Protein conserved in bacteria
G5S32_RS10370	COG4977	sequence-specific DNA binding
G5S32_RS10375	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
G5S32_RS10380	COG1121	(ABC) transporter
G5S32_RS10385	COG1108	ABC-type Mn2 Zn2 transport systems permease components
G5S32_RS10400	COG0508	dehydrogenase complex catalyzes the overall conversion of
G5S32_RS10405	COG0567	Dehydrogenase, E1 component
G5S32_RS10415	COG1053	succinate dehydrogenase
G5S32_RS10420	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
G5S32_RS10425	COG2009	succinate dehydrogenase
G5S32_RS10435	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
G5S32_RS10445	COG0033	Phosphoglucomutase
G5S32_RS10450	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
G5S32_RS10455	COG0596	Alpha beta hydrolase
G5S32_RS10470	COG1346	cytolysis
G5S32_RS10480	COG0583	DNA-binding transcription factor activity
G5S32_RS10490	COG0735	belongs to the Fur family
G5S32_RS10495	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
G5S32_RS10500	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G5S32_RS10505	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
G5S32_RS10515	COG0431	NADPH-dependent FMN reductase
G5S32_RS10525	COG3101	peptidyl-lysine hydroxylation
G5S32_RS10530	COG2860	membrane
G5S32_RS10535	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
G5S32_RS10540	COG2890	protein-(glutamine-N5) methyltransferase activity
G5S32_RS10545	COG2840	Smr protein MutS2
G5S32_RS10560	COG1987	bacterial-type flagellum assembly
G5S32_RS10610	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
G5S32_RS10620	COG1677	Flagellar hook-basal body complex protein FliE
G5S32_RS10630	COG4191	Histidine kinase
G5S32_RS10640	COG1516	flagellar protein fliS
G5S32_RS10650	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
G5S32_RS10655	COG1334	flagellar protein FlaG
G5S32_RS10660	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
G5S32_RS10675	COG2837	iron assimilation
G5S32_RS10695	COG1393	Belongs to the ArsC family
G5S32_RS10705	COG1876	peptidase activity
G5S32_RS10715	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
G5S32_RS10720	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G5S32_RS10730	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
G5S32_RS10750	COG4783	chaperone-mediated protein folding
G5S32_RS10755	COG1393	Belongs to the ArsC family
G5S32_RS10775	COG2233	PERMEase
G5S32_RS10780	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
G5S32_RS10785	COG0737	Belongs to the 5'-nucleotidase family
G5S32_RS10790	COG2877	3-deoxy-8-phosphooctulonate synthase activity
G5S32_RS10795	COG2912	Transglutaminase-like superfamily
G5S32_RS10805	COG2890	protein-(glutamine-N5) methyltransferase activity
G5S32_RS10815	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
G5S32_RS10820	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
G5S32_RS10830	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
G5S32_RS10835	COG3266	domain, Protein
G5S32_RS10840	COG0193	aminoacyl-tRNA hydrolase activity
G5S32_RS10935	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
G5S32_RS10950	COG1705	Flagellar rod assembly protein muramidase FlgJ
G5S32_RS10950	COG3951	Flagellar rod assembly protein muramidase FlgJ
G5S32_RS10955	COG1706	bacterial-type flagellum-dependent cell motility
G5S32_RS10960	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
G5S32_RS10990	COG1815	bacterial-type flagellum-dependent cell motility
G5S32_RS10995	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
G5S32_RS11000	COG0784	Response regulator, receiver
G5S32_RS11000	COG0835	chemotaxis
G5S32_RS11045	COG0840	transmembrane signaling receptor activity
G5S32_RS11055	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
G5S32_RS11060	COG2217	Heavy metal translocating P-type atpase
G5S32_RS11060	COG2608	mercury ion transmembrane transporter activity
G5S32_RS11080	COG2840	Smr protein MutS2
G5S32_RS11085	COG1187	pseudouridine synthase activity
G5S32_RS11090	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
G5S32_RS11095	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
G5S32_RS11100	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
G5S32_RS11105	COG0121	glutamine amidotransferase
G5S32_RS11110	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
G5S32_RS11115	COG1960	acyl-CoA dehydrogenase activity
G5S32_RS11130	COG0328	RNA-DNA hybrid ribonuclease activity
G5S32_RS11135	COG2226	methyltransferase
G5S32_RS11140	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G5S32_RS11145	COG0741	lytic transglycosylase activity
G5S32_RS11145	COG1388	LysM domain
G5S32_RS11155	COG3021	interspecies interaction between organisms
G5S32_RS11160	COG0347	Belongs to the P(II) protein family
G5S32_RS11170	COG0037	tRNA processing
G5S32_RS11175	COG0825	malonyl-CoA metabolic process
G5S32_RS11180	COG0587	DNA-directed DNA polymerase activity
G5S32_RS11185	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
G5S32_RS11200	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
G5S32_RS11205	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
G5S32_RS11210	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
G5S32_RS11220	COG0750	zinc metalloprotease
G5S32_RS11225	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
G5S32_RS11230	COG0575	Belongs to the CDS family
G5S32_RS11235	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
G5S32_RS11240	COG0233	cytoplasmic translational termination
G5S32_RS11250	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
G5S32_RS11255	COG0052	Belongs to the universal ribosomal protein uS2 family
G5S32_RS11260	COG0024	Methionine aminopeptidase
G5S32_RS11265	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
G5S32_RS11275	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
G5S32_RS11280	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
G5S32_RS11285	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
G5S32_RS11290	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
G5S32_RS11305	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
G5S32_RS11305	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
G5S32_RS11310	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
G5S32_RS11315	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
G5S32_RS11320	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
G5S32_RS11335	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
G5S32_RS11340	COG2252	PERMEase
G5S32_RS11345	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
G5S32_RS11355	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
G5S32_RS11360	COG1012	belongs to the aldehyde dehydrogenase family
G5S32_RS11365	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
G5S32_RS11370	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G5S32_RS11375	COG2195	Cleaves the N-terminal amino acid of tripeptides
G5S32_RS11380	COG4067	protein conserved in archaea
G5S32_RS11380	COG0189	ligase activity
G5S32_RS11385	COG0189	ligase activity
G5S32_RS11395	COG0733	neurotransmitter:sodium symporter activity
G5S32_RS11410	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
G5S32_RS11425	COG1477	protein flavinylation
G5S32_RS11435	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
G5S32_RS11450	COG1805	sodium ion transport
G5S32_RS11455	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
G5S32_RS11460	COG0271	Belongs to the BolA IbaG family
G5S32_RS11475	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
G5S32_RS11480	COG2211	Major facilitator Superfamily
G5S32_RS11485	COG2814	Major facilitator Superfamily
G5S32_RS11490	COG3248	Nucleoside-binding outer membrane protein
G5S32_RS11495	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
G5S32_RS11500	COG0693	protein deglycase activity
G5S32_RS11505	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
G5S32_RS11510	COG2166	iron-sulfur cluster assembly
G5S32_RS11515	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
G5S32_RS11520	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
G5S32_RS11530	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
G5S32_RS11530	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
G5S32_RS11540	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
G5S32_RS11545	COG1074	ATP-dependent DNA helicase activity
G5S32_RS11550	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
G5S32_RS11555	COG0583	DNA-binding transcription factor activity
G5S32_RS11560	COG3141	response to X-ray
G5S32_RS11565	COG2171	N-acyltransferase activity
G5S32_RS11570	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
G5S32_RS11575	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
G5S32_RS11580	COG0730	response to heat
G5S32_RS11590	COG0494	nUDIX hydrolase
G5S32_RS11600	COG0667	Aldo Keto reductase
G5S32_RS11610	COG2204	response regulator
G5S32_RS11615	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
G5S32_RS11635	COG0513	Belongs to the DEAD box helicase family
G5S32_RS11665	COG3154	lipid carrier protein
G5S32_RS11675	COG0826	peptidase U32
G5S32_RS11680	COG0826	peptidase U32
G5S32_RS11685	COG0560	Phosphoserine phosphatase
G5S32_RS11695	COG0813	purine-nucleoside phosphorylase activity
G5S32_RS11700	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
G5S32_RS11705	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
G5S32_RS11710	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
G5S32_RS11715	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
G5S32_RS11740	COG0084	hydrolase, TatD family'
G5S32_RS11755	COG1115	amino acid carrier protein
G5S32_RS11770	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
G5S32_RS11775	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
G5S32_RS11785	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
G5S32_RS11790	COG0083	homoserine kinase activity
G5S32_RS11805	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
G5S32_RS11815	COG0745	RESPONSE REGULATOR receiver
G5S32_RS11825	COG2198	Histidine kinase
G5S32_RS11825	COG0784	Response regulator, receiver
G5S32_RS11825	COG5002	protein histidine kinase activity
G5S32_RS11830	COG1242	4 iron, 4 sulfur cluster binding
G5S32_RS11835	COG0069	glutamate synthase activity
G5S32_RS11835	COG0067	glutamate synthase
G5S32_RS11835	COG0070	glutamate synthase
G5S32_RS11845	COG0067	glutamate synthase
G5S32_RS11845	COG0070	glutamate synthase
G5S32_RS11845	COG0069	glutamate synthase activity
G5S32_RS11850	COG0493	'glutamate synthase
G5S32_RS11865	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
G5S32_RS11870	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
G5S32_RS11875	COG2860	membrane
G5S32_RS11880	COG0730	response to heat
G5S32_RS11885	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
G5S32_RS11890	COG0505	Belongs to the CarA family
G5S32_RS11900	COG0494	nUDIX hydrolase
G5S32_RS11905	COG0653	protein targeting
G5S32_RS11915	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
G5S32_RS11920	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
G5S32_RS11925	COG0849	cell division
G5S32_RS11930	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
G5S32_RS11935	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
G5S32_RS11940	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
G5S32_RS11945	COG0772	Belongs to the SEDS family
G5S32_RS11950	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
G5S32_RS11960	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
G5S32_RS11965	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
G5S32_RS11970	COG0768	penicillin binding
G5S32_RS11975	COG3116	cell division
G5S32_RS11980	COG0275	rRNA processing
G5S32_RS11990	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
G5S32_RS11995	COG3107	peptidoglycan biosynthetic process
G5S32_RS12000	COG0792	nuclease activity
G5S32_RS12005	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
G5S32_RS12010	COG2823	Periplasmic or secreted lipoprotein
G5S32_RS12015	COG2969	positive regulation of protein catabolic process
G5S32_RS12020	COG0625	glutathione transferase activity
G5S32_RS12025	COG2857	Cytochrome c1
G5S32_RS12030	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
G5S32_RS12035	COG0723	plastoquinol--plastocyanin reductase activity
G5S32_RS12040	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
G5S32_RS12045	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
G5S32_RS12050	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
G5S32_RS12065	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G5S32_RS12075	COG0336	Belongs to the RNA methyltransferase TrmD family
G5S32_RS12080	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
G5S32_RS12085	COG0228	four-way junction DNA binding
G5S32_RS12090	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
G5S32_RS12095	COG4137	Cytochrome C assembly protein
G5S32_RS12100	COG4536	flavin adenine dinucleotide binding
G5S32_RS12110	COG2918	glutathione biosynthetic process
G5S32_RS12115	COG0612	Peptidase, M16
G5S32_RS12120	COG1238	metal cluster binding
G5S32_RS12130	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
G5S32_RS12135	COG0511	ligase activity, forming carbon-carbon bonds
G5S32_RS12135	COG5016	pyruvate
G5S32_RS12140	COG3630	sodium ion export across plasma membrane
G5S32_RS12190	COG0527	aspartate kinase activity
G5S32_RS12205	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
G5S32_RS12210	COG1546	Belongs to the CinA family
G5S32_RS12215	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
G5S32_RS12220	COG4208	sulfate ABC transporter
G5S32_RS12225	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
G5S32_RS12240	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
G5S32_RS12245	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
G5S32_RS12250	COG4942	peptidase
G5S32_RS12250	COG1388	LysM domain
G5S32_RS12260	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
G5S32_RS12265	COG0585	pseudouridine synthase activity
G5S32_RS12280	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
G5S32_RS12285	COG1968	undecaprenyl-diphosphatase activity
G5S32_RS12290	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
G5S32_RS12295	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
G5S32_RS12300	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
G5S32_RS12305	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
G5S32_RS12310	COG0828	Belongs to the bacterial ribosomal protein bS21 family
G5S32_RS12315	COG1610	YqeY-like protein
G5S32_RS12320	COG0358	DNA primase activity
G5S32_RS12400	COG2378	regulation of single-species biofilm formation
G5S32_RS12415	COG0840	transmembrane signaling receptor activity
G5S32_RS12425	COG3254	rhamnose metabolic process
G5S32_RS12430	COG1454	alcohol dehydrogenase
G5S32_RS12440	COG4771	TonB-dependent receptor
G5S32_RS12440	COG1629	transport
G5S32_RS12445	COG0748	coenzyme F420 binding
G5S32_RS12450	COG3721	Heme iron utilization protein
G5S32_RS12460	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
G5S32_RS12465	COG0811	peptide transport
G5S32_RS12470	COG0848	biopolymer transport protein
G5S32_RS12480	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G5S32_RS12500	COG1120	ATPase activity
G5S32_RS12505	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G5S32_RS12510	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G5S32_RS12515	COG4592	Periplasmic binding protein
G5S32_RS12520	COG2382	esterase
G5S32_RS12525	COG4677	pectinesterase activity
G5S32_RS12535	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
G5S32_RS12540	COG1349	DNA-binding transcription factor activity
G5S32_RS12545	COG0469	pyruvate kinase activity
G5S32_RS12550	COG3706	GGDEF domain
G5S32_RS12570	COG0668	transmembrane transport
G5S32_RS12575	COG0191	fructose-bisphosphate aldolase activity
G5S32_RS12585	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
G5S32_RS12610	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
G5S32_RS12615	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
G5S32_RS12630	COG2356	endonuclease I
G5S32_RS12635	COG1385	rRNA (uridine-N3-)-methyltransferase activity
G5S32_RS12640	COG0189	ligase activity
G5S32_RS12645	COG1678	Uncharacterized ACR, COG1678
G5S32_RS12650	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
G5S32_RS12665	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
G5S32_RS12670	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
G5S32_RS12675	COG0762	integral membrane protein
G5S32_RS12680	COG1872	DUF167
G5S32_RS12690	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
G5S32_RS12695	COG0635	Involved in the biosynthesis of porphyrin-containing compound
G5S32_RS12705	COG2066	Belongs to the glutaminase family
G5S32_RS12715	COG0220	tRNA (guanine-N7-)-methyltransferase activity
G5S32_RS12720	COG1194	a g-specific adenine glycosylase
G5S32_RS12725	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
G5S32_RS12730	COG0741	lytic transglycosylase activity
G5S32_RS12780	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
G5S32_RS12785	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
G5S32_RS12790	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
G5S32_RS12795	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
G5S32_RS12800	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
G5S32_RS12805	COG2967	ApaG domain
G5S32_RS12825	COG2966	Psort location CytoplasmicMembrane, score
G5S32_RS12845	COG0142	geranyltranstransferase activity
G5S32_RS12850	COG0531	amino acid
G5S32_RS12855	COG0039	L-malate dehydrogenase activity
G5S32_RS12860	COG1438	arginine binding
G5S32_RS12895	COG0312	modulator of DNA gyrase
G5S32_RS12900	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G5S32_RS12905	COG3164	Protein of unknown function
G5S32_RS12910	COG1530	ribonuclease E activity
G5S32_RS12915	COG0424	maF-like protein
G5S32_RS12920	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
G5S32_RS12925	COG1792	Involved in formation and maintenance of cell shape
G5S32_RS12930	COG1077	Cell shape determining protein MreB Mrl
G5S32_RS12960	COG4969	Belongs to the N-Me-Phe pilin family
G5S32_RS12965	COG2165	general secretion pathway protein
G5S32_RS12970	COG1459	type II secretion system
G5S32_RS12975	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
G5S32_RS12985	COG3267	Type II secretory pathway component ExeA
G5S32_RS12985	COG3409	Peptidoglycan-binding domain 1 protein
G5S32_RS13010	COG2199	diguanylate cyclase activity
G5S32_RS13010	COG2200	EAL domain
G5S32_RS13015	COG0629	single-stranded DNA binding
G5S32_RS13030	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
G5S32_RS13045	COG0527	aspartate kinase activity
G5S32_RS13050	COG1410	methionine synthase
G5S32_RS13050	COG0646	methionine synthase
G5S32_RS13120	COG0175	sulfate reduction
G5S32_RS13125	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G5S32_RS13130	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
G5S32_RS13150	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
G5S32_RS13200	COG0735	belongs to the Fur family
G5S32_RS13220	COG0305	Participates in initiation and elongation during chromosome replication
G5S32_RS13230	COG0359	binds to the 23S rRNA
G5S32_RS13235	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
G5S32_RS13240	COG2965	DNA replication, synthesis of RNA primer
G5S32_RS13245	COG0360	Binds together with S18 to 16S ribosomal RNA
G5S32_RS13255	COG2906	2 iron, 2 sulfur cluster binding
G5S32_RS13265	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
G5S32_RS13270	COG0049	tRNA binding
G5S32_RS13280	COG2168	tRNA wobble position uridine thiolation
G5S32_RS13285	COG2923	Belongs to the DsrF TusC family
G5S32_RS13290	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
G5S32_RS13295	COG2964	Protein conserved in bacteria
G5S32_RS13300	COG0545	Peptidyl-prolyl cis-trans isomerase
G5S32_RS13310	COG2900	Belongs to the SlyX family
G5S32_RS13315	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
G5S32_RS13320	COG0330	HflC and HflK could
G5S32_RS13325	COG0330	HflC and HflK could
G5S32_RS13330	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
G5S32_RS13335	COG1923	regulation of RNA biosynthetic process
G5S32_RS13345	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
G5S32_RS13355	COG0802	atpase or kinase
G5S32_RS13360	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
G5S32_RS13415	COG1162	GTPase activity
G5S32_RS13420	COG0688	phosphatidylethanolamine metabolic process
G5S32_RS13425	COG0471	metal ion transport
G5S32_RS13430	COG0640	Transcriptional regulator
G5S32_RS13435	COG0798	PFAM Bile acid sodium symporter
G5S32_RS13455	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G5S32_RS13460	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G5S32_RS13470	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
G5S32_RS13475	COG4942	peptidase
G5S32_RS13480	COG3437	response regulator, receiver
G5S32_RS13480	COG0784	Response regulator, receiver
G5S32_RS13490	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
G5S32_RS13495	COG2816	NAD+ diphosphatase activity
G5S32_RS13500	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
G5S32_RS13505	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
G5S32_RS13510	COG0085	RNA polymerase activity
G5S32_RS13515	COG0222	ribosome binding
G5S32_RS13520	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
G5S32_RS13530	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
G5S32_RS13535	COG0250	Participates in transcription elongation, termination and antitermination
G5S32_RS13540	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
G5S32_RS13545	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
G5S32_RS13570	COG1072	(Pantothenic acid kinase))
G5S32_RS13580	COG0812	UDP-N-acetylmuramate dehydrogenase activity
G5S32_RS13590	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G5S32_RS13670	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
G5S32_RS13685	COG3118	belongs to the thioredoxin family
G5S32_RS13690	COG0513	Belongs to the DEAD box helicase family
G5S32_RS13695	COG0248	Ppx GppA phosphatase
G5S32_RS13705	COG3290	protein histidine kinase activity
G5S32_RS13710	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
G5S32_RS13715	COG2205	protein histidine kinase activity
G5S32_RS13715	COG2198	Histidine kinase
G5S32_RS13715	COG0784	Response regulator, receiver
G5S32_RS13720	COG2814	Major facilitator Superfamily
G5S32_RS13735	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G5S32_RS13745	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
G5S32_RS13750	COG0511	ligase activity, forming carbon-carbon bonds
G5S32_RS13755	COG0439	Biotin carboxylase
G5S32_RS13775	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
G5S32_RS13795	COG0138	bifunctional purine biosynthesis protein purh
G5S32_RS13800	COG0151	Belongs to the GarS family
G5S32_RS13810	COG0776	regulation of translation
G5S32_RS13825	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G5S32_RS13830	COG1573	uracil-dna glycosylase
G5S32_RS13860	COG2852	Protein conserved in bacteria
G5S32_RS13865	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
G5S32_RS13870	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
G5S32_RS13920	COG0562	UDP-galactopyranose mutase
G5S32_RS13925	COG2244	polysaccharide biosynthetic process
G5S32_RS13980	COG2895	sulfate adenylyltransferase (ATP) activity
G5S32_RS13990	COG0529	Catalyzes the synthesis of activated sulfate
G5S32_RS13995	COG0471	metal ion transport
G5S32_RS13995	COG3273	potassium ion transport
G5S32_RS14000	COG0175	sulfate reduction
G5S32_RS14005	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G5S32_RS14015	COG1560	Kdo2-lipid A biosynthetic process
G5S32_RS14020	COG0859	PFAM glycosyl transferase family 9
G5S32_RS14030	COG1519	Transferase
G5S32_RS14055	COG2089	acid synthase
G5S32_RS14065	COG1083	cytidylyl-transferase
G5S32_RS14070	COG1086	Polysaccharide biosynthesis protein
G5S32_RS14085	COG0859	PFAM glycosyl transferase family 9
G5S32_RS14090	COG0463	Glycosyl transferase, family 2
G5S32_RS14100	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
G5S32_RS14140	COG2003	Belongs to the UPF0758 family
G5S32_RS14150	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
G5S32_RS14155	COG1309	transcriptional regulator
G5S32_RS14160	COG1560	Kdo2-lipid A biosynthetic process
G5S32_RS14165	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
G5S32_RS14175	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
G5S32_RS14180	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
G5S32_RS14185	COG1561	YicC-like family, N-terminal region
G5S32_RS14230	COG5001	Diguanylate cyclase
G5S32_RS14230	COG4251	negative regulation of phosphorylation
G5S32_RS14230	COG2203	Gaf domain
G5S32_RS14230	COG3706	GGDEF domain
G5S32_RS14235	COG2095	MarC family integral membrane protein
G5S32_RS14275	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
G5S32_RS14280	COG0640	Transcriptional regulator
G5S32_RS14285	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
G5S32_RS14290	COG2267	carboxylic ester hydrolase activity
G5S32_RS14295	COG0561	phosphatase activity
G5S32_RS14310	COG3287	FIST C domain
G5S32_RS14310	COG2199	diguanylate cyclase activity
G5S32_RS14310	COG2200	EAL domain
G5S32_RS14315	COG1011	Hydrolase
G5S32_RS14320	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
G5S32_RS14330	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
G5S32_RS14335	COG0019	diaminopimelate decarboxylase activity
G5S32_RS14345	COG1965	Belongs to the frataxin family
G5S32_RS14365	COG3072	Adenylate cyclase
G5S32_RS14375	COG1587	Uroporphyrinogen-III synthase
G5S32_RS14380	COG2959	enzyme of heme biosynthesis
G5S32_RS14385	COG3071	HemY protein
G5S32_RS14425	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
G5S32_RS14425	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
G5S32_RS14440	COG0084	hydrolase, TatD family'
G5S32_RS14455	COG0805	protein transport
G5S32_RS14460	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
G5S32_RS14480	COG2226	methyltransferase
G5S32_RS14485	COG1322	Protein conserved in bacteria
G5S32_RS14510	COG2160	L-arabinose isomerase activity
G5S32_RS14520	COG1069	ribulokinase activity
G5S32_RS14525	COG1879	ABC-type sugar transport system periplasmic component
G5S32_RS14530	COG1129	ABC transporter
G5S32_RS14535	COG1172	Belongs to the binding-protein-dependent transport system permease family
G5S32_RS14540	COG1879	ABC-type sugar transport system periplasmic component
G5S32_RS14545	COG1129	ABC transporter
G5S32_RS14550	COG1172	Belongs to the binding-protein-dependent transport system permease family
G5S32_RS14555	COG1172	Belongs to the binding-protein-dependent transport system permease family
G5S32_RS14575	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
G5S32_RS14595	COG1070	Carbohydrate kinase
G5S32_RS14605	COG0235	Class ii aldolase
G5S32_RS14610	COG2081	HI0933 family
G5S32_RS14620	COG1528	Iron-storage protein
G5S32_RS14625	COG0589	response to stress
G5S32_RS14645	COG1522	sequence-specific DNA binding
G5S32_RS14665	COG0006	proline dipeptidase activity
G5S32_RS14665	COG0006	proline dipeptidase activity
G5S32_RS14675	COG2022	thiamine diphosphate biosynthetic process
G5S32_RS14680	COG2104	thiamine diphosphate biosynthetic process
G5S32_RS14685	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
G5S32_RS14690	COG0352	thiamine-phosphate diphosphorylase activity
G5S32_RS14695	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
G5S32_RS14700	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
G5S32_RS14705	COG2132	Multicopper oxidase
G5S32_RS14710	COG3706	GGDEF domain
G5S32_RS14765	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
G5S32_RS14770	COG1739	Uncharacterized protein family UPF0029
G5S32_RS14780	COG0183	Belongs to the thiolase family
G5S32_RS14785	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
G5S32_RS14790	COG0355	proton-transporting ATP synthase activity, rotational mechanism
G5S32_RS14795	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
G5S32_RS14800	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
G5S32_RS14805	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
G5S32_RS14810	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
G5S32_RS14815	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
G5S32_RS14830	COG3312	ion transport
G5S32_RS14835	COG1475	DNA binding
G5S32_RS14840	COG1192	Involved in chromosome partitioning
G5S32_RS14845	COG0357	Ribosomal RNA small subunit methyltransferase G
G5S32_RS14850	COG0445	tRNA wobble uridine modification
G5S32_RS14855	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
G5S32_RS14875	COG0594	ribonuclease P activity
G5S32_RS14880	COG0230	Belongs to the bacterial ribosomal protein bL34 family
G5S32_RS14920	COG2244	polysaccharide biosynthetic process
G5S32_RS14930	COG1442	glycosyl transferase family 8
G5S32_RS14940	COG0463	Glycosyl transferase, family 2
G5S32_RS14955	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
G5S32_RS14960	COG2244	polysaccharide biosynthetic process
G5S32_RS15000	COG4191	Histidine kinase
G5S32_RS15040	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
G5S32_RS15060	COG4786	Flagellar basal body rod
G5S32_RS15060	COG1256	bacterial-type flagellum assembly
G5S32_RS15070	COG1706	bacterial-type flagellum-dependent cell motility
G5S32_RS15075	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
G5S32_RS15080	COG4786	Flagellar basal body rod
G5S32_RS15085	COG4787	bacterial-type flagellum-dependent cell motility
G5S32_RS15090	COG1749	Flagellar hook protein flgE
G5S32_RS15095	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
G5S32_RS15100	COG1558	bacterial-type flagellum-dependent cell motility
G5S32_RS15105	COG1815	bacterial-type flagellum-dependent cell motility
G5S32_RS15125	COG0741	lytic transglycosylase activity
G5S32_RS15145	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
G5S32_RS15155	COG1677	Flagellar hook-basal body complex protein FliE
G5S32_RS15185	COG1987	bacterial-type flagellum assembly
G5S32_RS15195	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
G5S32_RS15210	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
G5S32_RS15215	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
G5S32_RS15235	COG1580	Controls the rotational direction of flagella during chemotaxis
G5S32_RS15240	COG1191	sigma factor activity
G5S32_RS15245	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
G5S32_RS15250	COG1360	Flagellar Motor Protein
G5S32_RS15265	COG0523	cobalamin synthesis protein
G5S32_RS15285	COG0513	Belongs to the DEAD box helicase family
G5S32_RS15290	COG0589	response to stress
G5S32_RS15305	COG0419	ATPase involved in DNA repair
G5S32_RS15310	COG0420	3'-5' exonuclease activity
G5S32_RS15315	COG1609	Transcriptional regulator
G5S32_RS15320	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
G5S32_RS15320	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
G5S32_RS15325	COG1105	Belongs to the carbohydrate kinase PfkB family
G5S32_RS15330	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
G5S32_RS15330	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G5S32_RS15330	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G5S32_RS15340	COG0625	glutathione transferase activity
G5S32_RS15345	COG0189	ligase activity
G5S32_RS15345	COG4067	protein conserved in archaea
G5S32_RS15355	COG0602	queuosine metabolic process
G5S32_RS15360	COG1328	CTP reductase activity
G5S32_RS15410	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G5S32_RS15430	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G5S32_RS15435	COG1454	alcohol dehydrogenase
G5S32_RS15440	COG3395	kinase activity
G5S32_RS15445	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
G5S32_RS15450	COG1349	DNA-binding transcription factor activity
G5S32_RS15490	COG0714	Associated with various cellular activities
G5S32_RS15495	COG0641	radical SAM
G5S32_RS15500	COG3119	arylsulfatase activity
G5S32_RS15505	COG0583	DNA-binding transcription factor activity
G5S32_RS15510	COG0745	RESPONSE REGULATOR receiver
G5S32_RS15525	COG1794	racemase activity, acting on amino acids and derivatives
G5S32_RS15540	COG1028	Short-chain dehydrogenase reductase Sdr
G5S32_RS15555	COG3122	Protein conserved in bacteria
G5S32_RS15565	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G5S32_RS15590	COG1051	belongs to the nudix hydrolase family
G5S32_RS15620	COG4628	conserved protein (DUF2132)
G5S32_RS15635	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G5S32_RS15815	COG1475	DNA binding
G5S32_RS15950	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
G5S32_RS15975	COG0513	Belongs to the DEAD box helicase family
G5S32_RS16005	COG1397	ADP-ribosylglycohydrolase
G5S32_RS16025	COG1312	Catalyzes the dehydration of D-mannonate
G5S32_RS16030	COG0246	Mannitol dehydrogenase
G5S32_RS16035	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
G5S32_RS16045	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
G5S32_RS16050	COG1904	glucuronate isomerase
G5S32_RS16060	COG2721	sulfolactate sulfo-lyase activity
G5S32_RS16075	COG0625	glutathione transferase activity
G5S32_RS16080	COG1464	Belongs to the NlpA lipoprotein family
G5S32_RS16085	COG0518	GMP synthase (glutamine-hydrolyzing) activity
G5S32_RS16085	COG0519	Catalyzes the synthesis of GMP from XMP
G5S32_RS16090	COG5002	protein histidine kinase activity
G5S32_RS16090	COG3447	MASE1 domain protein
G5S32_RS16090	COG5001	Diguanylate cyclase
G5S32_RS16095	COG2866	Carboxypeptidase
G5S32_RS16100	COG0583	DNA-binding transcription factor activity
G5S32_RS16105	COG1028	Short-chain dehydrogenase reductase Sdr
G5S32_RS16120	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
G5S32_RS16125	COG4604	ABC transporter, ATP-binding protein
G5S32_RS16130	COG4605	iron ion homeostasis
G5S32_RS16135	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G5S32_RS16150	COG0840	transmembrane signaling receptor activity
G5S32_RS16170	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G5S32_RS16170	COG4191	Histidine kinase
G5S32_RS16175	COG0784	Response regulator, receiver
G5S32_RS16175	COG3437	response regulator, receiver
G5S32_RS16180	COG0840	transmembrane signaling receptor activity
G5S32_RS16200	COG1765	OsmC-like protein
G5S32_RS16215	COG3300	MHYT domain
G5S32_RS16215	COG5001	Diguanylate cyclase
G5S32_RS16245	COG1522	sequence-specific DNA binding
G5S32_RS16250	COG0531	amino acid
G5S32_RS16255	COG0840	transmembrane signaling receptor activity
G5S32_RS16285	COG0633	Ferredoxin
G5S32_RS16285	COG3217	Mosc domain protein beta barrel domain protein
G5S32_RS16290	COG0418	dihydroorotase activity
G5S32_RS16300	COG4134	Bacterial extracellular solute-binding protein
G5S32_RS16305	COG4135	transport system, permease component
G5S32_RS16310	COG4136	ATPase activity
G5S32_RS16315	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
G5S32_RS16375	COG0582	viral genome integration into host DNA
G5S32_RS16380	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
G5S32_RS16395	COG1063	alcohol dehydrogenase
G5S32_RS16400	COG0156	8-amino-7-oxononanoate synthase activity
G5S32_RS16405	COG1012	belongs to the aldehyde dehydrogenase family
G5S32_RS16410	COG3284	Transcriptional regulator
G5S32_RS16415	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
G5S32_RS16425	COG0346	lactoylglutathione lyase activity
G5S32_RS16430	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G5S32_RS16435	COG0642	Histidine kinase
G5S32_RS16440	COG0745	RESPONSE REGULATOR receiver
G5S32_RS16465	COG0513	Belongs to the DEAD box helicase family
G5S32_RS16480	COG1120	ATPase activity
G5S32_RS16485	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G5S32_RS16490	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G5S32_RS16495	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
G5S32_RS16500	COG4774	siderophore transport
G5S32_RS16515	COG3384	dioxygenase
G5S32_RS16520	COG0583	DNA-binding transcription factor activity
G5S32_RS16525	COG1342	Belongs to the UPF0251 family
G5S32_RS16530	COG0583	DNA-binding transcription factor activity
G5S32_RS16545	COG1846	Transcriptional regulator
G5S32_RS16565	COG1301	dicarboxylic acid transport
G5S32_RS16570	COG4565	transcriptional regulatory protein
G5S32_RS16575	COG3290	protein histidine kinase activity
G5S32_RS16580	COG0471	metal ion transport
G5S32_RS16585	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
G5S32_RS16595	COG2169	Transcriptional regulator
G5S32_RS16600	COG2259	Doxx family
G5S32_RS16620	COG0363	glucosamine-6-phosphate deaminase activity
G5S32_RS16650	COG0110	maltose O-acetyltransferase activity
G5S32_RS16660	COG1376	ErfK ybiS ycfS ynhG family protein
G5S32_RS16660	COG1388	LysM domain
G5S32_RS16665	COG0415	Belongs to the DNA photolyase family
G5S32_RS16670	COG0789	Transcriptional regulator
G5S32_RS16675	COG3272	Protein of unknown function (DUF1722)
G5S32_RS16680	COG0813	purine-nucleoside phosphorylase activity
G5S32_RS16695	COG3706	GGDEF domain
G5S32_RS16705	COG1566	PFAM secretion protein HlyD family protein
G5S32_RS16750	COG1162	GTPase activity
G5S32_RS16755	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
G5S32_RS16765	COG0739	heme binding
G5S32_RS16770	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
G5S32_RS16770	COG2213	PTS system mannitol-specific
G5S32_RS16775	COG0246	Mannitol dehydrogenase
G5S32_RS16780	COG3722	fumarate hydratase activity
G5S32_RS16795	COG0471	metal ion transport
G5S32_RS16800	COG0596	Alpha beta hydrolase
G5S32_RS16835	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
G5S32_RS16840	COG1640	4-alpha-glucanotransferase
G5S32_RS16845	COG0058	SHG alpha-glucan phosphorylase activity
G5S32_RS16850	COG2909	trisaccharide binding
G5S32_RS16860	COG1785	Belongs to the alkaline phosphatase family
G5S32_RS16870	COG3477	response to acidic pH
G5S32_RS16880	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
G5S32_RS16885	COG1845	cytochrome c oxidase, subunit III
G5S32_RS16890	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
G5S32_RS16895	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
G5S32_RS16900	COG2084	Dehydrogenase
G5S32_RS16915	COG0217	transcriptional regulatory protein
G5S32_RS16945	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
G5S32_RS16950	COG1444	tRNA N-acetyltransferase activity
G5S32_RS16955	COG2199	diguanylate cyclase activity
G5S32_RS16955	COG2202	Pas domain
G5S32_RS16955	COG2200	EAL domain
G5S32_RS16965	COG2274	protein secretion by the type I secretion system
G5S32_RS17015	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G5S32_RS17035	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
G5S32_RS17100	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
G5S32_RS17105	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
G5S32_RS17120	COG3383	formate dehydrogenase (NAD+) activity
G5S32_RS17135	COG1132	(ABC) transporter
G5S32_RS17150	COG0406	alpha-ribazole phosphatase activity
G5S32_RS17155	COG0454	-acetyltransferase
G5S32_RS17160	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
G5S32_RS17175	COG4580	involved in the transport of maltose and maltodextrins
G5S32_RS17210	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G5S32_RS17220	COG0366	Alpha amylase catalytic
G5S32_RS17230	COG4989	oxidoreductase activity
G5S32_RS17275	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
G5S32_RS17285	COG5001	Diguanylate cyclase
G5S32_RS17285	COG4251	negative regulation of phosphorylation
G5S32_RS17285	COG2203	Gaf domain
G5S32_RS17285	COG3706	GGDEF domain
G5S32_RS17310	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
G5S32_RS17320	COG0477	Major facilitator Superfamily
G5S32_RS17330	COG0402	S-adenosylhomocysteine deaminase activity
G5S32_RS17335	COG1979	alcohol dehydrogenase
G5S32_RS17340	COG0534	Mate efflux family protein
G5S32_RS17350	COG0789	Transcriptional regulator
G5S32_RS17365	COG1028	Short-chain dehydrogenase reductase Sdr
G5S32_RS17370	COG2723	6-phospho-beta-galactosidase activity
G5S32_RS17375	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G5S32_RS17375	COG1263	PTS System
G5S32_RS17380	COG3265	gluconokinase activity
G5S32_RS17385	COG0129	dihydroxy-acid dehydratase activity
G5S32_RS17390	COG1609	Transcriptional regulator
G5S32_RS17405	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G5S32_RS17410	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G5S32_RS17415	COG1120	ATPase activity
G5S32_RS17425	COG4774	siderophore transport
G5S32_RS17430	COG0251	oxidation-reduction process
G5S32_RS17440	COG2223	nitrite transmembrane transporter activity
G5S32_RS17445	COG0561	phosphatase activity
G5S32_RS17465	COG0477	Major facilitator Superfamily
G5S32_RS17495	COG0535	radical SAM domain protein
G5S32_RS17510	COG4657	Part of a membrane complex involved in electron transport
G5S32_RS17515	COG2878	Part of a membrane complex involved in electron transport
G5S32_RS17520	COG4656	Part of a membrane complex involved in electron transport
G5S32_RS17550	COG0513	Belongs to the DEAD box helicase family
G5S32_RS17555	COG0697	spore germination
G5S32_RS17560	COG2067	long-chain fatty acid transport protein
G5S32_RS17585	COG1811	Na channel or pump
G5S32_RS17590	COG0583	DNA-binding transcription factor activity
G5S32_RS17595	COG0400	carboxylic ester hydrolase activity
G5S32_RS17610	COG0488	(ABC) transporter
G5S32_RS17615	COG0443	Heat shock 70 kDa protein
G5S32_RS17620	COG0095	Lipoate-protein ligase
G5S32_RS17625	COG0840	transmembrane signaling receptor activity
G5S32_RS17645	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
G5S32_RS17650	COG0673	inositol 2-dehydrogenase activity
G5S32_RS17655	COG4702	Belongs to the UPF0303 family
G5S32_RS17675	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G5S32_RS17690	COG2130	NADP-dependent
G5S32_RS17695	COG1309	transcriptional regulator
G5S32_RS17700	COG0564	pseudouridine synthase activity
G5S32_RS17715	COG1846	Transcriptional regulator
G5S32_RS17735	COG0840	transmembrane signaling receptor activity
G5S32_RS17740	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
G5S32_RS17745	COG0573	inorganic phosphate transmembrane transporter activity
G5S32_RS17750	COG0581	inorganic phosphate transmembrane transporter activity
G5S32_RS17755	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
G5S32_RS17760	COG2199	diguanylate cyclase activity
G5S32_RS17775	COG0659	secondary active sulfate transmembrane transporter activity
G5S32_RS17790	COG0739	heme binding
G5S32_RS17805	COG0678	peroxiredoxin activity
G5S32_RS17805	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
G5S32_RS17810	COG0697	spore germination
G5S32_RS17815	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
G5S32_RS17820	COG1764	response to oxidative stress
G5S32_RS17825	COG1846	Transcriptional regulator
G5S32_RS17830	COG0179	Fumarylacetoacetate (FAA) hydrolase
G5S32_RS17845	COG0668	transmembrane transport
G5S32_RS17850	COG0569	domain protein
G5S32_RS17855	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
G5S32_RS17865	COG3123	guanosine phosphorylase activity
G5S32_RS17870	COG1741	Belongs to the pirin family
G5S32_RS17910	COG3706	GGDEF domain
G5S32_RS17920	COG1846	Transcriptional regulator
G5S32_RS17925	COG2315	Protein conserved in bacteria
G5S32_RS17930	COG0784	Response regulator, receiver
G5S32_RS17930	COG0835	chemotaxis
G5S32_RS17935	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
G5S32_RS17940	COG2862	Uncharacterized protein family, UPF0114
G5S32_RS17955	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
G5S32_RS17960	COG4771	TonB-dependent receptor
G5S32_RS17975	COG0612	Peptidase, M16
G5S32_RS17980	COG0811	peptide transport
G5S32_RS18010	COG0583	DNA-binding transcription factor activity
G5S32_RS18035	COG0583	DNA-binding transcription factor activity
G5S32_RS18055	COG2197	response regulator
G5S32_RS18060	COG0393	Putative heavy-metal-binding
G5S32_RS18070	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G5S32_RS18080	COG3842	ATPase activity
G5S32_RS18090	COG1175	transmembrane transport
G5S32_RS18095	COG3833	ABC-type maltose transport systems, permease component
G5S32_RS18115	COG4948	Mandelate Racemase Muconate Lactonizing
G5S32_RS18145	COG2814	Major facilitator Superfamily
G5S32_RS18170	COG0583	DNA-binding transcription factor activity
G5S32_RS18210	COG3069	C4-dicarboxylate transmembrane transporter activity
G5S32_RS18215	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
G5S32_RS18230	COG2354	Protein conserved in bacteria
G5S32_RS18235	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
G5S32_RS18250	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
G5S32_RS18255	COG2194	sulfuric ester hydrolase activity
G5S32_RS18260	COG1280	lysine exporter protein (LysE YggA)
G5S32_RS18265	COG2207	Transcriptional regulator
G5S32_RS18270	COG5001	Diguanylate cyclase
G5S32_RS18270	COG3300	MHYT domain
G5S32_RS18280	COG3724	N-succinylarginine dihydrolase activity
G5S32_RS18305	COG4948	Mandelate Racemase Muconate Lactonizing
G5S32_RS18330	COG0583	DNA-binding transcription factor activity
G5S32_RS18340	COG3706	GGDEF domain
G5S32_RS18355	COG2176	DNA-directed DNA polymerase activity
G5S32_RS18365	COG5001	Diguanylate cyclase
G5S32_RS18370	COG3530	Putative quorum-sensing-regulated virulence factor
G5S32_RS18380	COG2304	oxidoreductase activity
G5S32_RS18385	COG2304	oxidoreductase activity
G5S32_RS18400	COG0714	Associated with various cellular activities
G5S32_RS18425	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G5S32_RS18435	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
G5S32_RS18470	COG0109	protoheme IX farnesyltransferase activity
G5S32_RS18485	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
G5S32_RS18495	COG0840	transmembrane signaling receptor activity
G5S32_RS18505	COG1901	pseudouridine methyltransferase
G5S32_RS18510	COG1278	Cold shock
G5S32_RS18525	COG1139	Iron-sulfur cluster binding protein
G5S32_RS18530	COG0247	lactate metabolic process
G5S32_RS18535	COG0583	DNA-binding transcription factor activity
G5S32_RS18545	COG1067	ATP-dependent peptidase activity
G5S32_RS18560	COG0366	Alpha amylase catalytic
G5S32_RS18570	COG2195	Cleaves the N-terminal amino acid of tripeptides
G5S32_RS18580	COG4681	YaeQ
G5S32_RS18590	COG1278	Cold shock
G5S32_RS18595	COG3036	rescue of stalled ribosome
G5S32_RS18615	COG0745	RESPONSE REGULATOR receiver
G5S32_RS18625	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
G5S32_RS18625	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
G5S32_RS18635	COG0516	GMP reductase activity
G5S32_RS18650	COG2207	Transcriptional regulator
G5S32_RS18675	COG1447	Phosphotransferase system cellobiose-specific component IIA
G5S32_RS18680	COG2723	6-phospho-beta-galactosidase activity
G5S32_RS18685	COG1917	Cupin 2, conserved barrel domain protein
G5S32_RS18685	COG2169	Transcriptional regulator
G5S32_RS18715	COG0583	DNA-binding transcription factor activity
G5S32_RS18720	COG3976	FMN-binding domain protein
G5S32_RS18720	COG1053	succinate dehydrogenase
G5S32_RS18720	COG0431	NADPH-dependent FMN reductase
G5S32_RS18725	COG0431	NADPH-dependent FMN reductase
G5S32_RS18725	COG3976	FMN-binding domain protein
G5S32_RS18725	COG1053	succinate dehydrogenase
G5S32_RS18730	COG0583	DNA-binding transcription factor activity
G5S32_RS18740	COG0656	L-ascorbic acid biosynthetic process
G5S32_RS18745	COG1064	alcohol dehydrogenase
G5S32_RS18755	COG0583	DNA-binding transcription factor activity
G5S32_RS18765	COG0673	inositol 2-dehydrogenase activity
G5S32_RS18770	COG2207	Transcriptional regulator
G5S32_RS18790	COG2211	Major facilitator Superfamily
G5S32_RS18795	COG0673	inositol 2-dehydrogenase activity
G5S32_RS18800	COG1609	Transcriptional regulator
G5S32_RS18805	COG1349	DNA-binding transcription factor activity
G5S32_RS18820	COG1028	Short-chain dehydrogenase reductase Sdr
G5S32_RS18825	COG2207	Transcriptional regulator
G5S32_RS18840	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
G5S32_RS18870	COG3713	MltA-interacting MipA family protein
G5S32_RS18905	COG1280	lysine exporter protein (LysE YggA)
G5S32_RS18910	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
G5S32_RS18915	COG0656	L-ascorbic acid biosynthetic process
G5S32_RS18930	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
G5S32_RS18935	COG2721	sulfolactate sulfo-lyase activity
G5S32_RS18945	COG2271	Major facilitator Superfamily
G5S32_RS18960	COG4948	Mandelate Racemase Muconate Lactonizing
G5S32_RS18970	COG2084	Dehydrogenase
G5S32_RS18975	COG1929	Belongs to the glycerate kinase type-1 family
G5S32_RS18980	COG3835	regulator
G5S32_RS18990	COG0840	transmembrane signaling receptor activity
G5S32_RS18995	COG0840	transmembrane signaling receptor activity
G5S32_RS19005	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
G5S32_RS19010	COG0363	glucosamine-6-phosphate deaminase activity
G5S32_RS19015	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
G5S32_RS19045	COG2239	Acts as a magnesium transporter
G5S32_RS19055	COG2113	Glycine betaine
G5S32_RS19060	COG4176	ABC-type proline glycine betaine transport system permease component
G5S32_RS19065	COG4175	Glycine betaine
G5S32_RS19070	COG1166	arginine decarboxylase activity
G5S32_RS19075	COG0010	Belongs to the arginase family
G5S32_RS19080	COG1522	sequence-specific DNA binding
G5S32_RS19085	COG0626	cystathionine gamma-synthase activity
G5S32_RS19090	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
G5S32_RS19095	COG0765	amino acid transport
G5S32_RS19105	COG2985	domain, Protein
G5S32_RS19110	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
G5S32_RS19125	COG1085	galactose-1-phosphate uridylyltransferase
G5S32_RS19135	COG5426	von Willebrand factor, type A
G5S32_RS19140	COG3119	arylsulfatase activity
G5S32_RS19145	COG3119	arylsulfatase activity
G5S32_RS19150	COG0641	radical SAM
G5S32_RS19165	COG0601	transmembrane transport
G5S32_RS19170	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G5S32_RS19200	COG0823	Involved in the tonB-independent uptake of proteins
G5S32_RS19210	COG4677	pectinesterase activity
G5S32_RS19225	COG1175	transmembrane transport
G5S32_RS19230	COG0395	ABC-type sugar transport system, permease component
G5S32_RS19235	COG3842	ATPase activity
G5S32_RS19240	COG1653	transport
G5S32_RS19250	COG0534	Mate efflux family protein
G5S32_RS19260	COG1917	Cupin 2, conserved barrel domain protein
G5S32_RS19280	COG1396	sequence-specific DNA binding
G5S32_RS19285	COG3135	benzoate transporter
G5S32_RS19295	COG1028	Short-chain dehydrogenase reductase Sdr
G5S32_RS19310	COG0386	Belongs to the glutathione peroxidase family
G5S32_RS19320	COG4943	cyclic-guanylate-specific phosphodiesterase activity
G5S32_RS19325	COG0840	transmembrane signaling receptor activity
G5S32_RS19335	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
G5S32_RS19335	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
G5S32_RS19340	COG0509	glycine decarboxylation via glycine cleavage system
G5S32_RS19350	COG0404	The glycine cleavage system catalyzes the degradation of glycine
G5S32_RS19360	COG1368	sulfuric ester hydrolase activity
G5S32_RS19365	COG2202	Pas domain
G5S32_RS19365	COG2200	EAL domain
G5S32_RS19365	COG2199	diguanylate cyclase activity
G5S32_RS19370	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G5S32_RS19385	COG0546	phosphoglycolate phosphatase activity
G5S32_RS19395	COG1324	tolerance protein
G5S32_RS19405	COG0484	heat shock protein binding
G5S32_RS19415	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
G5S32_RS19425	COG4181	ATPase activity
G5S32_RS19430	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
G5S32_RS19440	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
G5S32_RS19455	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
G5S32_RS19460	COG0840	transmembrane signaling receptor activity
G5S32_RS19465	COG0814	amino acid
G5S32_RS19470	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
G5S32_RS19475	COG0513	Belongs to the DEAD box helicase family
G5S32_RS19480	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G5S32_RS19525	COG3118	belongs to the thioredoxin family
G5S32_RS19530	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
G5S32_RS19535	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
G5S32_RS19575	COG0438	transferase activity, transferring glycosyl groups
G5S32_RS19575	COG0297	glycogen (starch) synthase activity
G5S32_RS19600	COG0346	lactoylglutathione lyase activity
G5S32_RS19610	COG2926	Belongs to the UPF0265 family
G5S32_RS19620	COG3132	Protein of unknown function, DUF480
G5S32_RS19625	COG2827	Endonuclease containing a URI domain
G5S32_RS19630	COG1879	ABC-type sugar transport system periplasmic component
G5S32_RS19635	COG0784	Response regulator, receiver
G5S32_RS19635	COG5002	protein histidine kinase activity
G5S32_RS19650	COG1492	cobalamin metabolic process
G5S32_RS19655	COG0725	ABC transporter, periplasmic molybdate-binding protein
G5S32_RS19660	COG4149	molybdate abc transporter
G5S32_RS19665	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
G5S32_RS19680	COG1289	transmembrane transporter activity
G5S32_RS19685	COG0210	DNA helicase
G5S32_RS19690	COG1335	isochorismatase
G5S32_RS19695	COG1803	Methylglyoxal synthase
G5S32_RS19700	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
G5S32_RS19755	COG3038	cytochrome b561
G5S32_RS19765	COG2116	formate transmembrane transporter activity
G5S32_RS19770	COG0583	DNA-binding transcription factor activity
G5S32_RS19780	COG3593	DNA synthesis involved in DNA repair
G5S32_RS19785	COG0737	Belongs to the 5'-nucleotidase family
G5S32_RS19800	COG2824	Alkylphosphonate utilization operon protein PhnA
G5S32_RS19805	COG0750	zinc metalloprotease
G5S32_RS19815	COG2050	protein possibly involved in aromatic compounds catabolism
G5S32_RS19835	COG0583	DNA-binding transcription factor activity
G5S32_RS19840	COG0045	succinate-CoA ligase (ADP-forming) activity
G5S32_RS19840	COG1042	CoA-binding domain protein
G5S32_RS19840	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G5S32_RS19865	COG0023	Translation Initiation Factor
G5S32_RS19940	COG3140	Belongs to the UPF0181 family
G5S32_RS19955	COG0745	RESPONSE REGULATOR receiver
G5S32_RS19965	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
G5S32_RS19970	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
G5S32_RS19985	COG3706	GGDEF domain
G5S32_RS20040	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G5S32_RS20050	COG0561	phosphatase activity
G5S32_RS20060	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G5S32_RS20060	COG1522	sequence-specific DNA binding
G5S32_RS20065	COG2313	pseudouridylate synthase activity
G5S32_RS20070	COG0667	Aldo Keto reductase
G5S32_RS20075	COG2423	ornithine cyclodeaminase activity
G5S32_RS20085	COG1902	pentaerythritol trinitrate reductase activity
G5S32_RS20095	COG3381	protein complex oligomerization
G5S32_RS20110	COG0579	oxidoreductase
G5S32_RS20115	COG2755	lipolytic protein G-D-S-L family
G5S32_RS20115	COG0657	acetylesterase activity
G5S32_RS20125	COG0004	ammonium transporteR
G5S32_RS20140	COG1902	pentaerythritol trinitrate reductase activity
G5S32_RS20145	COG0583	DNA-binding transcription factor activity
G5S32_RS20175	COG0583	DNA-binding transcription factor activity
G5S32_RS20180	COG0642	Histidine kinase
G5S32_RS20185	COG0745	RESPONSE REGULATOR receiver
G5S32_RS20210	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
G5S32_RS20215	COG2159	amidohydrolase
G5S32_RS20220	COG0583	DNA-binding transcription factor activity
G5S32_RS20255	COG3384	dioxygenase
G5S32_RS20260	COG0745	RESPONSE REGULATOR receiver
G5S32_RS20265	COG0642	Histidine kinase
G5S32_RS20285	COG1653	transport
G5S32_RS20330	COG0789	Transcriptional regulator
G5S32_RS20335	COG0110	maltose O-acetyltransferase activity
G5S32_RS20365	COG0583	DNA-binding transcription factor activity
G5S32_RS20390	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G5S32_RS20410	COG1132	(ABC) transporter
G5S32_RS20415	COG1132	(ABC) transporter
G5S32_RS20420	COG1979	alcohol dehydrogenase
G5S32_RS20435	COG1733	regulation of RNA biosynthetic process
G5S32_RS20440	COG0730	response to heat
G5S32_RS20445	COG0583	DNA-binding transcription factor activity
G5S32_RS20455	COG0583	DNA-binding transcription factor activity
G5S32_RS20470	COG0840	transmembrane signaling receptor activity
G5S32_RS20495	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
G5S32_RS20500	COG0183	Belongs to the thiolase family
G5S32_RS20505	COG3246	L-lysine catabolic process to acetate
G5S32_RS20515	COG0583	DNA-binding transcription factor activity
G5S32_RS20520	COG1028	Short-chain dehydrogenase reductase Sdr
G5S32_RS20525	COG0183	Belongs to the thiolase family
G5S32_RS20550	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
G5S32_RS20555	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
G5S32_RS20565	COG0668	transmembrane transport
G5S32_RS20585	COG2425	protein containing a von Willebrand factor type A (vWA) domain
G5S32_RS20600	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
G5S32_RS20625	COG2501	S4 domain
G5S32_RS20635	COG2197	response regulator
G5S32_RS20650	COG3706	GGDEF domain
G5S32_RS20660	COG2203	Gaf domain
G5S32_RS20660	COG4251	negative regulation of phosphorylation
G5S32_RS20660	COG3706	GGDEF domain
G5S32_RS20660	COG5001	Diguanylate cyclase
G5S32_RS20665	COG2205	protein histidine kinase activity
G5S32_RS20665	COG0784	Response regulator, receiver
G5S32_RS20680	COG4172	Belongs to the ABC transporter superfamily
G5S32_RS20685	COG4239	(ABC) transporter, permease
G5S32_RS20690	COG4174	ABC transporter (Permease)
G5S32_RS20695	COG4166	transmembrane transport
G5S32_RS20715	COG0435	Glutathione S-transferase
G5S32_RS20725	COG2188	Transcriptional regulator
G5S32_RS20730	COG1011	Hydrolase
G5S32_RS20745	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
G5S32_RS20750	COG2759	Belongs to the formate--tetrahydrofolate ligase family
G5S32_RS20755	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G5S32_RS20755	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G5S32_RS20770	COG4302	ethanolamine ammonia-lyase activity
G5S32_RS20775	COG0531	amino acid
G5S32_RS20780	COG0302	gtp cyclohydrolase
G5S32_RS20800	COG2897	thiosulfate sulfurtransferase activity
G5S32_RS20815	COG2358	TRAP transporter, solute receptor (TAXI family
G5S32_RS20820	COG2390	Transcriptional regulator
G5S32_RS20830	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
G5S32_RS20835	COG0840	transmembrane signaling receptor activity
G5S32_RS20855	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G5S32_RS20865	COG0456	acetyltransferase
G5S32_RS20875	COG3069	C4-dicarboxylate transmembrane transporter activity
G5S32_RS20880	COG0437	4 iron, 4 sulfur cluster binding
G5S32_RS20885	COG0348	domain, Protein
G5S32_RS20890	COG2197	response regulator
G5S32_RS20895	COG3850	Histidine kinase
G5S32_RS20900	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
G5S32_RS20900	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
G5S32_RS20910	COG0243	molybdopterin cofactor binding
G5S32_RS20915	COG3043	anaerobic respiration
G5S32_RS20920	COG3005	denitrification pathway
G5S32_RS20950	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
G5S32_RS20955	COG0830	nickel cation binding
G5S32_RS20965	COG0804	urea catabolic process
G5S32_RS20970	COG0832	Belongs to the urease beta subunit family
G5S32_RS20975	COG0831	urea catabolic process
G5S32_RS20980	COG0829	nickel cation binding
G5S32_RS21010	COG0784	Response regulator, receiver
G5S32_RS21010	COG2198	Histidine kinase
G5S32_RS21010	COG5002	protein histidine kinase activity
G5S32_RS21015	COG0745	RESPONSE REGULATOR receiver
G5S32_RS21035	COG0840	transmembrane signaling receptor activity
G5S32_RS21040	COG0840	transmembrane signaling receptor activity
G5S32_RS21055	COG0697	spore germination
G5S32_RS21060	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G5S32_RS21080	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
G5S32_RS21085	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
G5S32_RS21090	COG4139	cobalamin transport
G5S32_RS21095	COG4948	Mandelate Racemase Muconate Lactonizing
G5S32_RS21115	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
G5S32_RS21120	COG3958	Transketolase
G5S32_RS21125	COG3959	Transketolase, thiamine diphosphate binding domain
G5S32_RS21130	COG1172	Belongs to the binding-protein-dependent transport system permease family
G5S32_RS21135	COG1129	ABC transporter
G5S32_RS21145	COG1879	ABC-type sugar transport system periplasmic component
G5S32_RS21170	COG3381	protein complex oligomerization
G5S32_RS21175	COG3302	dmso reductase anchor subunit
G5S32_RS21180	COG0437	4 iron, 4 sulfur cluster binding
G5S32_RS21185	COG0243	molybdopterin cofactor binding
G5S32_RS21190	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
G5S32_RS21190	COG2221	Nitrite and sulphite reductase 4Fe-4S
G5S32_RS21200	COG4221	oxidoreductase activity
G5S32_RS21205	COG1953	Uracil, thiamine, allantoin
G5S32_RS21225	COG2267	carboxylic ester hydrolase activity
G5S32_RS21230	COG0251	oxidation-reduction process
G5S32_RS21235	COG1335	isochorismatase
G5S32_RS21245	COG1309	transcriptional regulator
G5S32_RS21250	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
G5S32_RS21285	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
G5S32_RS21290	COG1028	Short-chain dehydrogenase reductase Sdr
G5S32_RS21295	COG1574	metal-dependent hydrolase with the TIM-barrel fold
G5S32_RS21310	COG0444	Belongs to the ABC transporter superfamily
G5S32_RS21320	COG0601	transmembrane transport
G5S32_RS21330	COG4948	Mandelate Racemase Muconate Lactonizing
G5S32_RS21335	COG2186	Transcriptional regulator
G5S32_RS21340	COG4948	Mandelate Racemase Muconate Lactonizing
G5S32_RS21360	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G5S32_RS21370	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
G5S32_RS21375	COG3409	Peptidoglycan-binding domain 1 protein
G5S32_RS21375	COG3267	Type II secretory pathway component ExeA
G5S32_RS21385	COG0489	protein tyrosine kinase activity
G5S32_RS21400	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
G5S32_RS21425	COG0367	asparagine synthase
G5S32_RS21430	COG0438	transferase activity, transferring glycosyl groups
G5S32_RS21440	COG0438	transferase activity, transferring glycosyl groups
G5S32_RS21445	COG2755	lipolytic protein G-D-S-L family
G5S32_RS21445	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups