locus-tag	class	description
DBX26_RS00025	COG0515	serine threonine protein kinase
DBX26_RS00030	COG1609	Transcriptional regulator
DBX26_RS00035	COG0129	dihydroxy-acid dehydratase activity
DBX26_RS00040	COG3265	gluconokinase activity
DBX26_RS00045	COG2610	gluconate transmembrane transporter activity
DBX26_RS00050	COG0800	Aldolase
DBX26_RS00055	COG3721	Heme iron utilization protein
DBX26_RS00060	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DBX26_RS00065	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
DBX26_RS00075	COG1522	sequence-specific DNA binding
DBX26_RS00080	COG0742	ribosomal rna small subunit methyltransferase
DBX26_RS00095	COG0589	response to stress
DBX26_RS00100	COG1528	Iron-storage protein
DBX26_RS00110	COG2081	HI0933 family
DBX26_RS00140	COG4964	Belongs to the GSP D family
DBX26_RS00190	COG0748	coenzyme F420 binding
DBX26_RS00200	COG4988	ABC transporter
DBX26_RS00205	COG1132	(ABC) transporter
DBX26_RS00225	COG1322	Protein conserved in bacteria
DBX26_RS00230	COG2226	methyltransferase
DBX26_RS00235	COG3165	ubiquinone biosynthetic process from chorismate
DBX26_RS00240	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
DBX26_RS00250	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DBX26_RS00255	COG0805	protein transport
DBX26_RS00260	COG3263	regulation of cellular component size
DBX26_RS00265	COG0084	hydrolase, TatD family'
DBX26_RS00290	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DBX26_RS00290	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DBX26_RS00295	COG0218	Necessary for normal cell division and for the maintenance of normal septation
DBX26_RS00330	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DBX26_RS00340	COG2204	response regulator
DBX26_RS00345	COG3852	Histidine kinase
DBX26_RS00355	COG0174	glutamine synthetase
DBX26_RS00360	COG1217	gtp-binding protein TYPA
DBX26_RS00375	COG1295	ribonuclease BN
DBX26_RS00380	COG1490	D-aminoacyl-tRNA deacylase activity
DBX26_RS00385	COG0456	acetyltransferase
DBX26_RS00395	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
DBX26_RS00400	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DBX26_RS00405	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
DBX26_RS00410	COG3031	protein transport across the cell outer membrane
DBX26_RS00420	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DBX26_RS00425	COG1459	type II secretion system
DBX26_RS00430	COG2165	general secretion pathway protein
DBX26_RS00435	COG2165	general secretion pathway protein
DBX26_RS00440	COG2165	general secretion pathway protein
DBX26_RS00445	COG4795	General secretion pathway protein
DBX26_RS00450	COG3156	type II secretion system protein K
DBX26_RS00455	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
DBX26_RS00460	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
DBX26_RS00470	COG1218	3'(2'),5'-bisphosphate nucleotidase
DBX26_RS00475	COG0494	nUDIX hydrolase
DBX26_RS00485	COG1040	competence protein
DBX26_RS00490	COG0596	Alpha beta hydrolase
DBX26_RS00500	COG2183	response to ionizing radiation
DBX26_RS00510	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DBX26_RS00530	COG2233	PERMEase
DBX26_RS00540	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DBX26_RS00545	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DBX26_RS00550	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DBX26_RS00555	COG1758	RNA polymerase activity
DBX26_RS00560	COG0194	GDP metabolic process
DBX26_RS00575	COG0848	biopolymer transport protein
DBX26_RS00580	COG0811	peptide transport
DBX26_RS00600	COG4174	ABC transporter (Permease)
DBX26_RS00605	COG4239	(ABC) transporter, permease
DBX26_RS00610	COG0747	negative chemotaxis
DBX26_RS00615	COG0444	Belongs to the ABC transporter superfamily
DBX26_RS00620	COG4608	Belongs to the ABC transporter superfamily
DBX26_RS00645	COG1561	YicC-like family, N-terminal region
DBX26_RS00655	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
DBX26_RS00660	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DBX26_RS00665	COG1560	Kdo2-lipid A biosynthetic process
DBX26_RS00670	COG1309	transcriptional regulator
DBX26_RS00675	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DBX26_RS00680	COG2003	Belongs to the UPF0758 family
DBX26_RS00700	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DBX26_RS00705	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DBX26_RS00710	COG0438	transferase activity, transferring glycosyl groups
DBX26_RS00715	COG0859	PFAM glycosyl transferase family 9
DBX26_RS00725	COG0438	transferase activity, transferring glycosyl groups
DBX26_RS00730	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
DBX26_RS00735	COG3642	lipopolysaccharide core region biosynthetic process
DBX26_RS00755	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DBX26_RS00775	COG1519	Transferase
DBX26_RS00780	COG0859	PFAM glycosyl transferase family 9
DBX26_RS00785	COG1560	Kdo2-lipid A biosynthetic process
DBX26_RS00795	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DBX26_RS00830	COG0175	sulfate reduction
DBX26_RS00835	COG3273	potassium ion transport
DBX26_RS00835	COG0471	metal ion transport
DBX26_RS00840	COG0529	Catalyzes the synthesis of activated sulfate
DBX26_RS00855	COG2895	sulfate adenylyltransferase (ATP) activity
DBX26_RS00895	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DBX26_RS00925	COG2089	acid synthase
DBX26_RS00950	COG5433	transposase activity
DBX26_RS00955	COG1045	serine acetyltransferase
DBX26_RS01040	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DBX26_RS01055	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
DBX26_RS01065	COG0149	triose-phosphate isomerase activity
DBX26_RS01080	COG3152	Membrane
DBX26_RS01095	COG1494	fructose-1,6-bisphosphatase
DBX26_RS01110	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
DBX26_RS01115	COG1575	Belongs to the MenA family. Type 1 subfamily
DBX26_RS01120	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
DBX26_RS01135	COG1609	Transcriptional regulator
DBX26_RS01140	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DBX26_RS01145	COG0254	rRNA binding
DBX26_RS01155	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DBX26_RS01160	COG0088	Forms part of the polypeptide exit tunnel
DBX26_RS01170	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DBX26_RS01175	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DBX26_RS01180	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DBX26_RS01185	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DBX26_RS01195	COG0255	Belongs to the universal ribosomal protein uL29 family
DBX26_RS01200	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DBX26_RS01210	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DBX26_RS01215	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DBX26_RS01230	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DBX26_RS01245	COG1841	ribosomal large subunit assembly
DBX26_RS01250	COG0200	Binds to the 23S rRNA
DBX26_RS01255	COG0201	protein transport
DBX26_RS01260	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DBX26_RS01265	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DBX26_RS01270	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DBX26_RS01280	COG0202	RNA polymerase activity
DBX26_RS01285	COG0203	ribosomal protein L17
DBX26_RS01295	COG0545	Peptidyl-prolyl cis-trans isomerase
DBX26_RS01305	COG2153	protein acetylation
DBX26_RS01310	COG0513	Belongs to the DEAD box helicase family
DBX26_RS01320	COG0737	Belongs to the 5'-nucleotidase family
DBX26_RS01325	COG1648	precorrin-2 dehydrogenase activity
DBX26_RS01325	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DBX26_RS01330	COG0175	sulfate reduction
DBX26_RS01335	COG2895	sulfate adenylyltransferase (ATP) activity
DBX26_RS01340	COG0471	metal ion transport
DBX26_RS01340	COG3273	potassium ion transport
DBX26_RS01345	COG0529	Catalyzes the synthesis of activated sulfate
DBX26_RS01365	COG1136	(ABC) transporter
DBX26_RS01380	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
DBX26_RS01390	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DBX26_RS01400	COG2911	Protein conserved in bacteria
DBX26_RS01405	COG2105	PFAM AIG2 family protein
DBX26_RS01410	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
DBX26_RS01415	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
DBX26_RS01420	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DBX26_RS01425	COG0163	prenyltransferase activity
DBX26_RS01435	COG1178	ABC-type Fe3 transport system permease component
DBX26_RS01440	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
DBX26_RS01465	COG0039	L-malate dehydrogenase activity
DBX26_RS01475	COG0142	geranyltranstransferase activity
DBX26_RS01480	COG0261	This protein binds to 23S rRNA in the presence of protein L20
DBX26_RS01490	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DBX26_RS01495	COG2966	Psort location CytoplasmicMembrane, score
DBX26_RS01515	COG2967	ApaG domain
DBX26_RS01520	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DBX26_RS01525	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
DBX26_RS01530	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DBX26_RS01535	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
DBX26_RS01540	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
DBX26_RS01550	COG0066	3-isopropylmalate dehydratase activity
DBX26_RS01560	COG0473	3-isopropylmalate dehydrogenase activity
DBX26_RS01565	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DBX26_RS01580	COG0671	phosphoesterase, PA-phosphatase related
DBX26_RS01590	COG0583	DNA-binding transcription factor activity
DBX26_RS01595	COG1022	Amp-dependent synthetase and ligase
DBX26_RS01600	COG0028	Belongs to the TPP enzyme family
DBX26_RS01605	COG0440	acetolactate synthase activity
DBX26_RS01610	COG0469	pyruvate kinase activity
DBX26_RS01620	COG1349	DNA-binding transcription factor activity
DBX26_RS01625	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DBX26_RS01635	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DBX26_RS01635	COG1263	PTS System
DBX26_RS01640	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
DBX26_RS01645	COG3722	fumarate hydratase activity
DBX26_RS01650	COG0246	Mannitol dehydrogenase
DBX26_RS01655	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
DBX26_RS01655	COG2213	PTS system mannitol-specific
DBX26_RS01695	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DBX26_RS01780	COG0732	type I restriction modification DNA specificity domain
DBX26_RS01860	COG3550	peptidyl-serine autophosphorylation
DBX26_RS01880	COG0358	DNA primase activity
DBX26_RS01885	COG1610	YqeY-like protein
DBX26_RS01890	COG0828	Belongs to the bacterial ribosomal protein bS21 family
DBX26_RS01895	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DBX26_RS01900	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DBX26_RS01905	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
DBX26_RS01910	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
DBX26_RS01915	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DBX26_RS01920	COG1968	undecaprenyl-diphosphatase activity
DBX26_RS01925	COG0617	tRNA 3'-terminal CCA addition
DBX26_RS01930	COG3267	Type II secretory pathway component ExeA
DBX26_RS01930	COG3409	Peptidoglycan-binding domain 1 protein
DBX26_RS01940	COG4991	sh3 domain protein
DBX26_RS01945	COG0306	phosphate transporter
DBX26_RS01950	COG1392	Phosphate transport regulator
DBX26_RS01955	COG3025	triphosphatase activity
DBX26_RS01970	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
DBX26_RS01980	COG1538	Outer membrane efflux protein
DBX26_RS01985	COG0494	nUDIX hydrolase
DBX26_RS01990	COG3151	Protein conserved in bacteria
DBX26_RS02000	COG3150	esterase
DBX26_RS02010	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DBX26_RS02015	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DBX26_RS02025	COG3105	Protein conserved in bacteria
DBX26_RS02035	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
DBX26_RS02045	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DBX26_RS02050	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DBX26_RS02055	COG0723	plastoquinol--plastocyanin reductase activity
DBX26_RS02060	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DBX26_RS02065	COG2857	Cytochrome c1
DBX26_RS02070	COG0625	glutathione transferase activity
DBX26_RS02075	COG2969	positive regulation of protein catabolic process
DBX26_RS02080	COG2823	Periplasmic or secreted lipoprotein
DBX26_RS02085	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
DBX26_RS02100	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DBX26_RS02110	COG0275	rRNA processing
DBX26_RS02115	COG3116	cell division
DBX26_RS02120	COG0768	penicillin binding
DBX26_RS02125	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DBX26_RS02130	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DBX26_RS02135	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DBX26_RS02140	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DBX26_RS02145	COG0772	Belongs to the SEDS family
DBX26_RS02150	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DBX26_RS02155	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DBX26_RS02160	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
DBX26_RS02165	COG0849	cell division
DBX26_RS02170	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DBX26_RS02175	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
DBX26_RS02185	COG0653	protein targeting
DBX26_RS02190	COG0494	nUDIX hydrolase
DBX26_RS02200	COG0505	Belongs to the CarA family
DBX26_RS02205	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DBX26_RS02210	COG0730	response to heat
DBX26_RS02215	COG0583	DNA-binding transcription factor activity
DBX26_RS02220	COG2860	membrane
DBX26_RS02225	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DBX26_RS02235	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DBX26_RS02245	COG0493	'glutamate synthase
DBX26_RS02250	COG0069	glutamate synthase activity
DBX26_RS02250	COG0070	glutamate synthase
DBX26_RS02250	COG0067	glutamate synthase
DBX26_RS02260	COG0067	glutamate synthase
DBX26_RS02260	COG0069	glutamate synthase activity
DBX26_RS02260	COG0070	glutamate synthase
DBX26_RS02265	COG1242	4 iron, 4 sulfur cluster binding
DBX26_RS02270	COG0784	Response regulator, receiver
DBX26_RS02270	COG2198	Histidine kinase
DBX26_RS02270	COG5002	protein histidine kinase activity
DBX26_RS02280	COG0745	RESPONSE REGULATOR receiver
DBX26_RS02295	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
DBX26_RS02310	COG0083	homoserine kinase activity
DBX26_RS02315	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
DBX26_RS02320	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
DBX26_RS02325	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
DBX26_RS02330	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DBX26_RS02345	COG1115	amino acid carrier protein
DBX26_RS02350	COG3022	response to hydroperoxide
DBX26_RS02355	COG0513	Belongs to the DEAD box helicase family
DBX26_RS02360	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
DBX26_RS02375	COG4974	Belongs to the 'phage' integrase family
DBX26_RS02380	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DBX26_RS02385	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DBX26_RS02395	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DBX26_RS02400	COG3829	transcription factor binding
DBX26_RS02400	COG3290	protein histidine kinase activity
DBX26_RS02410	COG0667	Aldo Keto reductase
DBX26_RS02420	COG3066	DNA modification
DBX26_RS02435	COG0730	response to heat
DBX26_RS02440	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DBX26_RS02445	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
DBX26_RS02455	COG1283	sodium-dependent phosphate transmembrane transporter activity
DBX26_RS02460	COG0583	DNA-binding transcription factor activity
DBX26_RS02465	COG0640	Transcriptional regulator
DBX26_RS02470	COG0268	Binds directly to 16S ribosomal RNA
DBX26_RS02475	COG0728	peptidoglycan biosynthetic process
DBX26_RS02480	COG0196	riboflavin kinase activity
DBX26_RS02485	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DBX26_RS02490	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DBX26_RS02495	COG1047	Peptidyl-prolyl cis-trans
DBX26_RS02500	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DBX26_RS02505	COG3279	Response regulator of the LytR AlgR family
DBX26_RS02510	COG3275	phosphorelay sensor kinase activity
DBX26_RS02515	COG1966	Carbon starvation protein
DBX26_RS02535	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
DBX26_RS02540	COG1472	Belongs to the glycosyl hydrolase 3 family
DBX26_RS02545	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DBX26_RS02550	COG0287	Prephenate dehydrogenase
DBX26_RS02550	COG1605	Chorismate mutase
DBX26_RS02555	COG0739	heme binding
DBX26_RS02560	COG0488	(ABC) transporter
DBX26_RS02570	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
DBX26_RS02575	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
DBX26_RS02580	COG0077	Prephenate dehydratase
DBX26_RS02580	COG1605	Chorismate mutase
DBX26_RS02585	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DBX26_RS02590	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
DBX26_RS02595	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DBX26_RS02600	COG0564	pseudouridine synthase activity
DBX26_RS02610	COG0542	response to heat
DBX26_RS02625	COG1116	anion transmembrane transporter activity
DBX26_RS02685	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
DBX26_RS02695	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
DBX26_RS02700	COG0826	peptidase U32
DBX26_RS02705	COG2974	May be involved in recombination
DBX26_RS02715	COG0745	RESPONSE REGULATOR receiver
DBX26_RS02720	COG5002	protein histidine kinase activity
DBX26_RS02730	COG0248	Ppx GppA phosphatase
DBX26_RS02735	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
DBX26_RS02745	COG0581	inorganic phosphate transmembrane transporter activity
DBX26_RS02750	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DBX26_RS02755	COG0704	Plays a role in the regulation of phosphate uptake
DBX26_RS02765	COG3142	Participates in the control of copper homeostasis
DBX26_RS02770	COG0450	alkyl hydroperoxide reductase
DBX26_RS02775	COG0583	DNA-binding transcription factor activity
DBX26_RS02780	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
DBX26_RS02790	COG0517	IMP dehydrogenase activity
DBX26_RS02800	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DBX26_RS02805	COG0343	queuine tRNA-ribosyltransferase activity
DBX26_RS02810	COG1862	Preprotein translocase
DBX26_RS02815	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DBX26_RS02820	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DBX26_RS02825	COG0483	inositol monophosphate 1-phosphatase activity
DBX26_RS02830	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
DBX26_RS02840	COG1104	cysteine desulfurase activity
DBX26_RS02845	COG0822	iron-sulfur transferase activity
DBX26_RS02860	COG0443	Heat shock 70 kDa protein
DBX26_RS02865	COG0633	Ferredoxin
DBX26_RS02870	COG2975	iron-sulfur cluster assembly
DBX26_RS02875	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DBX26_RS02880	COG0105	UTP biosynthetic process
DBX26_RS02895	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
DBX26_RS02900	COG0124	histidyl-tRNA synthetase
DBX26_RS02905	COG2976	Protein conserved in bacteria
DBX26_RS02910	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DBX26_RS02915	COG1160	GTP binding
DBX26_RS02935	COG0517	IMP dehydrogenase activity
DBX26_RS02935	COG0516	GMP reductase activity
DBX26_RS02940	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DBX26_RS02940	COG0519	Catalyzes the synthesis of GMP from XMP
DBX26_RS02945	COG1757	Na H antiporter
DBX26_RS02950	COG1584	GPR1 FUN34 yaaH family protein
DBX26_RS02965	COG1473	amidohydrolase
DBX26_RS02975	COG1115	amino acid carrier protein
DBX26_RS02980	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DBX26_RS02990	COG2873	o-acetylhomoserine
DBX26_RS02995	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DBX26_RS03015	COG3153	acetyltransferase
DBX26_RS03015	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DBX26_RS03020	COG0583	DNA-binding transcription factor activity
DBX26_RS03025	COG0235	Class ii aldolase
DBX26_RS03030	COG4806	L-rhamnose isomerase
DBX26_RS03035	COG1070	Carbohydrate kinase
DBX26_RS03040	COG3254	rhamnose metabolic process
DBX26_RS03070	COG3850	Histidine kinase
DBX26_RS03075	COG2197	response regulator
DBX26_RS03085	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
DBX26_RS03090	COG2867	negative regulation of translational initiation
DBX26_RS03095	COG2914	Belongs to the UPF0125 (RnfH) family
DBX26_RS03100	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DBX26_RS03105	COG0497	DNA recombination
DBX26_RS03110	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DBX26_RS03115	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DBX26_RS03120	COG1301	dicarboxylic acid transport
DBX26_RS03130	COG0484	heat shock protein binding
DBX26_RS03160	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
DBX26_RS03175	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
DBX26_RS03180	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DBX26_RS03180	COG0047	phosphoribosylformylglycinamidine synthase activity
DBX26_RS03215	COG2195	Cleaves the N-terminal amino acid of tripeptides
DBX26_RS03220	COG2252	PERMEase
DBX26_RS03225	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
DBX26_RS03230	COG1073	alpha beta
DBX26_RS03240	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DBX26_RS03245	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DBX26_RS03250	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DBX26_RS03255	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DBX26_RS03255	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DBX26_RS03270	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
DBX26_RS03280	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
DBX26_RS03285	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
DBX26_RS03295	COG0142	geranyltranstransferase activity
DBX26_RS03305	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
DBX26_RS03310	COG2885	chlorophyll binding
DBX26_RS03315	COG0301	tRNA thio-modification
DBX26_RS03315	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DBX26_RS03325	COG0583	DNA-binding transcription factor activity
DBX26_RS03335	COG2363	Small membrane protein
DBX26_RS03340	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
DBX26_RS03345	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DBX26_RS03350	COG1611	Belongs to the LOG family
DBX26_RS03365	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
DBX26_RS03365	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
DBX26_RS03375	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
DBX26_RS03380	COG1464	Belongs to the NlpA lipoprotein family
DBX26_RS03385	COG2011	ABC-type metal ion transport system permease component
DBX26_RS03390	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DBX26_RS03395	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
DBX26_RS03405	COG1263	PTS System
DBX26_RS03405	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DBX26_RS03410	COG0366	Alpha amylase catalytic
DBX26_RS03420	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DBX26_RS03425	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DBX26_RS03430	COG0321	lipoyl(octanoyl) transferase activity
DBX26_RS03440	COG1686	Belongs to the peptidase S11 family
DBX26_RS03445	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
DBX26_RS03450	COG0772	Belongs to the SEDS family
DBX26_RS03455	COG0768	penicillin binding
DBX26_RS03465	COG0799	negative regulation of ribosome biogenesis
DBX26_RS03470	COG1466	dna polymerase III delta subunit
DBX26_RS03475	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
DBX26_RS03480	COG0495	leucyl-tRNA aminoacylation
DBX26_RS03485	COG2888	peptidyl-tyrosine sulfation
DBX26_RS03490	COG0815	Transfers the fatty acyl group on membrane lipoproteins
DBX26_RS03495	COG4535	Mg2 and Co2 transporter CorC
DBX26_RS03505	COG1702	phosphate starvation-inducible protein PhoH
DBX26_RS03510	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DBX26_RS03520	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DBX26_RS03630	COG0012	GTP binding
DBX26_RS03640	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DBX26_RS03645	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DBX26_RS03650	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
DBX26_RS03655	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
DBX26_RS03665	COG2890	protein-(glutamine-N5) methyltransferase activity
DBX26_RS03670	COG3094	Invasion gene expression up-regulator, SirB
DBX26_RS03675	COG2912	Transglutaminase-like superfamily
DBX26_RS03680	COG2877	3-deoxy-8-phosphooctulonate synthase activity
DBX26_RS03685	COG0737	Belongs to the 5'-nucleotidase family
DBX26_RS03690	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DBX26_RS03695	COG1187	pseudouridine synthase activity
DBX26_RS03700	COG2840	Smr protein MutS2
DBX26_RS03730	COG2217	Heavy metal translocating P-type atpase
DBX26_RS03730	COG2608	mercury ion transmembrane transporter activity
DBX26_RS03785	COG0835	chemotaxis
DBX26_RS03785	COG0784	Response regulator, receiver
DBX26_RS03790	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
DBX26_RS03795	COG1815	bacterial-type flagellum-dependent cell motility
DBX26_RS03800	COG1558	bacterial-type flagellum-dependent cell motility
DBX26_RS03810	COG1749	Flagellar hook protein flgE
DBX26_RS03815	COG4787	bacterial-type flagellum-dependent cell motility
DBX26_RS03825	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
DBX26_RS03830	COG1706	bacterial-type flagellum-dependent cell motility
DBX26_RS03835	COG1705	Flagellar rod assembly protein muramidase FlgJ
DBX26_RS03835	COG3951	Flagellar rod assembly protein muramidase FlgJ
DBX26_RS03845	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DBX26_RS03850	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DBX26_RS03855	COG2190	(PTS) system
DBX26_RS03860	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DBX26_RS03865	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DBX26_RS03875	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DBX26_RS03880	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
DBX26_RS03885	COG3115	cell septum assembly
DBX26_RS03890	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DBX26_RS03910	COG0330	HflC and HflK could
DBX26_RS03915	COG3118	belongs to the thioredoxin family
DBX26_RS03925	COG0300	oxidoreductase activity
DBX26_RS03930	COG1090	epimerase
DBX26_RS03960	COG0622	Phosphoesterase
DBX26_RS03980	COG3710	Transcriptional regulator
DBX26_RS03985	COG0326	Molecular chaperone. Has ATPase activity
DBX26_RS03995	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
DBX26_RS04000	COG3104	oligopeptide transport
DBX26_RS04005	COG0250	Participates in transcription elongation, termination and antitermination
DBX26_RS04010	COG0367	asparagine synthase
DBX26_RS04015	COG4651	solute:proton antiporter activity
DBX26_RS04015	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DBX26_RS04020	COG1846	Transcriptional regulator
DBX26_RS04020	COG1940	carbohydrate kinase activity
DBX26_RS04025	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
DBX26_RS04030	COG1263	PTS System
DBX26_RS04030	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DBX26_RS04030	COG2190	(PTS) system
DBX26_RS04035	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DBX26_RS04040	COG0735	belongs to the Fur family
DBX26_RS04060	COG0596	Alpha beta hydrolase
DBX26_RS04065	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
DBX26_RS04070	COG0033	Phosphoglucomutase
DBX26_RS04080	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DBX26_RS04095	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
DBX26_RS04100	COG1053	succinate dehydrogenase
DBX26_RS04110	COG0567	Dehydrogenase, E1 component
DBX26_RS04115	COG0508	dehydrogenase complex catalyzes the overall conversion of
DBX26_RS04120	COG0045	succinate-CoA ligase (ADP-forming) activity
DBX26_RS04130	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DBX26_RS04135	COG1121	(ABC) transporter
DBX26_RS04140	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
DBX26_RS04145	COG4977	sequence-specific DNA binding
DBX26_RS04150	COG1918	ferrous iron import across plasma membrane
DBX26_RS04170	COG0018	arginyl-trna synthetase
DBX26_RS04175	COG3102	Protein conserved in bacteria
DBX26_RS04190	COG0788	formyltetrahydrofolate deformylase activity
DBX26_RS04195	COG1199	ATP-dependent helicase activity
DBX26_RS04200	COG1214	PFAM Peptidase M22, glycoprotease
DBX26_RS04215	COG2267	carboxylic ester hydrolase activity
DBX26_RS04220	COG0318	PFAM AMP-dependent synthetase and ligase
DBX26_RS04225	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
DBX26_RS04230	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
DBX26_RS04235	COG2894	cell division
DBX26_RS04250	COG2951	lytic endotransglycosylase activity
DBX26_RS04255	COG0583	DNA-binding transcription factor activity
DBX26_RS04260	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DBX26_RS04265	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DBX26_RS04320	COG1028	Short-chain dehydrogenase reductase Sdr
DBX26_RS04330	COG1169	isochorismate synthase
DBX26_RS04335	COG1021	2,3-dihydroxybenzoate-AMP ligase
DBX26_RS04340	COG3433	isochorismatase activity
DBX26_RS04340	COG1535	isochorismatase
DBX26_RS04345	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DBX26_RS04345	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DBX26_RS04360	COG4771	TonB-dependent receptor
DBX26_RS04365	COG1253	flavin adenine dinucleotide binding
DBX26_RS04370	COG0513	Belongs to the DEAD box helicase family
DBX26_RS04375	COG0569	domain protein
DBX26_RS04380	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DBX26_RS04390	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
DBX26_RS04410	COG1175	transmembrane transport
DBX26_RS04420	COG3842	ATPase activity
DBX26_RS04425	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
DBX26_RS04430	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
DBX26_RS04435	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
DBX26_RS04445	COG2204	response regulator
DBX26_RS04465	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DBX26_RS04470	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DBX26_RS04475	COG0776	regulation of translation
DBX26_RS04480	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DBX26_RS04485	COG1555	photosystem II stabilization
DBX26_RS04500	COG0232	Belongs to the dGTPase family. Type 2 subfamily
DBX26_RS04505	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
DBX26_RS04510	COG0436	Aminotransferase
DBX26_RS04515	COG1169	isochorismate synthase
DBX26_RS04520	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
DBX26_RS04525	COG0596	Alpha beta hydrolase
DBX26_RS04530	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
DBX26_RS04550	COG2855	membrane
DBX26_RS04555	COG0477	Major facilitator Superfamily
DBX26_RS04600	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DBX26_RS04605	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DBX26_RS04620	COG1522	sequence-specific DNA binding
DBX26_RS04625	COG1946	Acyl-CoA thioesterase
DBX26_RS04630	COG3126	Type III secretion system lipoprotein chaperone (YscW)
DBX26_RS04650	COG0583	DNA-binding transcription factor activity
DBX26_RS04660	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DBX26_RS04665	COG0174	glutamine synthetase
DBX26_RS04670	COG0174	glutamine synthetase
DBX26_RS04680	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
DBX26_RS04685	COG3842	ATPase activity
DBX26_RS04690	COG1176	ABC-type spermidine putrescine transport system, permease component I
DBX26_RS04695	COG1177	transmembrane transport
DBX26_RS04705	COG1012	belongs to the aldehyde dehydrogenase family
DBX26_RS04710	COG0519	Catalyzes the synthesis of GMP from XMP
DBX26_RS04715	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DBX26_RS04720	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
DBX26_RS04725	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
DBX26_RS04730	COG0517	IMP dehydrogenase activity
DBX26_RS04730	COG0516	GMP reductase activity
DBX26_RS04755	COG0537	adenosine 5'-monophosphoramidase activity
DBX26_RS04780	COG3150	esterase
DBX26_RS04785	COG1252	NADH dehydrogenase
DBX26_RS04800	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DBX26_RS04810	COG4591	ABC-type transport system involved in lipoprotein release permease component
DBX26_RS04815	COG1136	(ABC) transporter
DBX26_RS04820	COG4591	ABC-type transport system involved in lipoprotein release permease component
DBX26_RS04830	COG0658	competence protein
DBX26_RS04830	COG2333	competence protein COMEC
DBX26_RS04835	COG1132	(ABC) transporter
DBX26_RS04850	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
DBX26_RS04855	COG2719	SpoVR family
DBX26_RS04860	COG2718	Belongs to the UPF0229 family
DBX26_RS04865	COG2766	serine protein kinase
DBX26_RS04885	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DBX26_RS04895	COG1882	Formate acetyltransferase
DBX26_RS04930	COG0708	Exodeoxyribonuclease III
DBX26_RS04935	COG0583	DNA-binding transcription factor activity
DBX26_RS04945	COG1346	cytolysis
DBX26_RS04955	COG3923	Primosomal replication protein n
DBX26_RS04960	COG0730	response to heat
DBX26_RS04965	COG1199	ATP-dependent helicase activity
DBX26_RS04975	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
DBX26_RS04980	COG1187	pseudouridine synthase activity
DBX26_RS04990	COG1278	Cold shock
DBX26_RS04995	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
DBX26_RS05000	COG0542	response to heat
DBX26_RS05005	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DBX26_RS05010	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
DBX26_RS05015	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
DBX26_RS05025	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DBX26_RS05035	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DBX26_RS05040	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DBX26_RS05045	COG0297	glycogen (starch) synthase activity
DBX26_RS05065	COG3070	regulator of competence-specific genes
DBX26_RS05070	COG1609	Transcriptional regulator
DBX26_RS05075	COG3381	protein complex oligomerization
DBX26_RS05080	COG0745	RESPONSE REGULATOR receiver
DBX26_RS05085	COG1434	Gram-negative-bacterium-type cell wall biogenesis
DBX26_RS05090	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DBX26_RS05095	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
DBX26_RS05100	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
DBX26_RS05105	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
DBX26_RS05135	COG4067	protein conserved in archaea
DBX26_RS05135	COG0189	ligase activity
DBX26_RS05145	COG0500	methyltransferase
DBX26_RS05150	COG4106	trans-aconitate 2-methyltransferase activity
DBX26_RS05155	COG1801	Protein of unknown function DUF72
DBX26_RS05165	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
DBX26_RS05170	COG0632	four-way junction helicase activity
DBX26_RS05175	COG2255	four-way junction helicase activity
DBX26_RS05180	COG1271	oxidase subunit
DBX26_RS05185	COG1294	oxidase, subunit
DBX26_RS05190	COG4890	Cyd operon protein YbgT
DBX26_RS05200	COG0824	Thioesterase
DBX26_RS05205	COG0811	peptide transport
DBX26_RS05220	COG0823	Involved in the tonB-independent uptake of proteins
DBX26_RS05225	COG2885	chlorophyll binding
DBX26_RS05230	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
DBX26_RS05235	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
DBX26_RS05245	COG3766	membrane
DBX26_RS05255	COG0754	glutathionylspermidine amidase activity
DBX26_RS05265	COG0784	Response regulator, receiver
DBX26_RS05265	COG2205	protein histidine kinase activity
DBX26_RS05310	COG3052	prosthetic group binding
DBX26_RS05325	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DBX26_RS05335	COG1396	sequence-specific DNA binding
DBX26_RS05340	COG3135	benzoate transporter
DBX26_RS05345	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DBX26_RS05350	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DBX26_RS05385	COG0686	Belongs to the AlaDH PNT family
DBX26_RS05395	COG1674	ftsk spoiiie
DBX26_RS05400	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
DBX26_RS05405	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DBX26_RS05415	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DBX26_RS05420	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
DBX26_RS05425	COG0156	8-amino-7-oxononanoate synthase activity
DBX26_RS05435	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
DBX26_RS05445	COG0501	Belongs to the peptidase M48B family
DBX26_RS05455	COG4221	oxidoreductase activity
DBX26_RS05470	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DBX26_RS05490	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DBX26_RS05500	COG0482	sulfurtransferase activity
DBX26_RS05510	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DBX26_RS05520	COG1757	Na H antiporter
DBX26_RS05535	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
DBX26_RS05540	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DBX26_RS05545	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DBX26_RS05550	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
DBX26_RS05550	COG0131	Imidazoleglycerol-phosphate dehydratase
DBX26_RS05555	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DBX26_RS05560	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
DBX26_RS05565	COG0107	imidazoleglycerol-phosphate synthase activity
DBX26_RS05570	COG0140	phosphoribosyl-ATP diphosphatase activity
DBX26_RS05570	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DBX26_RS05575	COG3012	SEC-C Motif Domain Protein
DBX26_RS05580	COG5433	transposase activity
DBX26_RS05590	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
DBX26_RS05595	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DBX26_RS05600	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DBX26_RS05605	COG0215	cysteine-tRNA ligase activity
DBX26_RS05610	COG1435	thymidine kinase activity
DBX26_RS05615	COG1434	Gram-negative-bacterium-type cell wall biogenesis
DBX26_RS05630	COG2116	formate transmembrane transporter activity
DBX26_RS05635	COG0390	transport system, permease component
DBX26_RS05640	COG4459	periplasmic nitrate reductase
DBX26_RS05645	COG3005	denitrification pathway
DBX26_RS05650	COG0243	molybdopterin cofactor binding
DBX26_RS05665	COG1227	inorganic diphosphatase activity
DBX26_RS05675	COG4172	Belongs to the ABC transporter superfamily
DBX26_RS05700	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
DBX26_RS05705	COG1842	Phage shock protein A
DBX26_RS05715	COG1983	PspC domain protein
DBX26_RS05735	COG2818	Glycosylase
DBX26_RS05740	COG0626	cystathionine gamma-synthase activity
DBX26_RS05750	COG0733	neurotransmitter:sodium symporter activity
DBX26_RS05755	COG0564	pseudouridine synthase activity
DBX26_RS05765	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DBX26_RS05770	COG1151	hydroxylamine reductase activity
DBX26_RS05775	COG3604	Transcriptional regulator
DBX26_RS05785	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DBX26_RS05790	COG4136	ATPase activity
DBX26_RS05795	COG4135	transport system, permease component
DBX26_RS05800	COG4134	Bacterial extracellular solute-binding protein
DBX26_RS05810	COG3313	Fe-S protein
DBX26_RS05825	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
DBX26_RS05835	COG0642	Histidine kinase
DBX26_RS05850	COG1061	Type III restriction enzyme res subunit
DBX26_RS05855	COG1187	pseudouridine synthase activity
DBX26_RS05860	COG2814	Major facilitator Superfamily
DBX26_RS05890	COG3005	denitrification pathway
DBX26_RS05895	COG0702	epimerase
DBX26_RS05900	COG0534	Mate efflux family protein
DBX26_RS05905	COG1136	(ABC) transporter
DBX26_RS05920	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
DBX26_RS05930	COG1960	acyl-CoA dehydrogenase activity
DBX26_RS05935	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
DBX26_RS05940	COG2985	domain, Protein
DBX26_RS05940	COG3273	potassium ion transport
DBX26_RS05945	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
DBX26_RS05950	COG1454	alcohol dehydrogenase
DBX26_RS05950	COG1012	belongs to the aldehyde dehydrogenase family
DBX26_RS05955	COG1737	Transcriptional regulator
DBX26_RS05960	COG0076	glutamate decarboxylase activity
DBX26_RS05970	COG2431	L-lysine efflux transmembrane transporter activity
DBX26_RS05990	COG3070	regulator of competence-specific genes
DBX26_RS06005	COG4191	Histidine kinase
DBX26_RS06005	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DBX26_RS06015	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DBX26_RS06025	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
DBX26_RS06030	COG4988	ABC transporter
DBX26_RS06035	COG0492	ferredoxin-NADP+ reductase activity
DBX26_RS06055	COG0471	metal ion transport
DBX26_RS06060	COG2949	membrane
DBX26_RS06065	COG0281	malic enzyme
DBX26_RS06070	COG1643	Atp-dependent helicase
DBX26_RS06085	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DBX26_RS06120	COG0247	lactate metabolic process
DBX26_RS06120	COG0277	FAD linked oxidase domain protein
DBX26_RS06125	COG2020	methyltransferase activity
DBX26_RS06130	COG0583	DNA-binding transcription factor activity
DBX26_RS06135	COG3384	dioxygenase
DBX26_RS06140	COG0435	Glutathione S-transferase
DBX26_RS06150	COG0010	Belongs to the arginase family
DBX26_RS06155	COG1228	amidohydrolase
DBX26_RS06175	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DBX26_RS06185	COG0291	Belongs to the bacterial ribosomal protein bL35 family
DBX26_RS06200	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DBX26_RS06205	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DBX26_RS06205	COG0072	phenylalanine-tRNA ligase activity
DBX26_RS06210	COG1621	beta-fructofuranosidase activity
DBX26_RS06215	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DBX26_RS06235	COG0776	regulation of translation
DBX26_RS06245	COG0500	methyltransferase
DBX26_RS06250	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
DBX26_RS06255	COG0295	cytidine deaminase activity
DBX26_RS06260	COG1346	cytolysis
DBX26_RS06265	COG1380	Effector of murein hydrolase LrgA
DBX26_RS06270	COG2925	Exonuclease
DBX26_RS06300	COG1823	symporter activity
DBX26_RS06305	COG0702	epimerase
DBX26_RS06310	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DBX26_RS06320	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
DBX26_RS06340	COG2988	succinylglutamate desuccinylase activity
DBX26_RS06345	COG4139	cobalamin transport
DBX26_RS06370	COG0583	DNA-binding transcription factor activity
DBX26_RS06380	COG1451	nucleotide metabolic process
DBX26_RS06385	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
DBX26_RS06450	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
DBX26_RS06455	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DBX26_RS06470	COG2195	Cleaves the N-terminal amino acid of tripeptides
DBX26_RS06480	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
DBX26_RS06490	COG0625	glutathione transferase activity
DBX26_RS06520	COG0477	Major facilitator Superfamily
DBX26_RS06520	COG2814	Major facilitator Superfamily
DBX26_RS06545	COG2010	Cytochrome c
DBX26_RS06555	COG2814	Major facilitator Superfamily
DBX26_RS06605	COG1129	ABC transporter
DBX26_RS06610	COG1172	Belongs to the binding-protein-dependent transport system permease family
DBX26_RS06615	COG1172	Belongs to the binding-protein-dependent transport system permease family
DBX26_RS06635	COG1609	Transcriptional regulator
DBX26_RS06640	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DBX26_RS06640	COG2190	(PTS) system
DBX26_RS06640	COG1263	PTS System
DBX26_RS06645	COG2723	6-phospho-beta-galactosidase activity
DBX26_RS06650	COG4580	involved in the transport of maltose and maltodextrins
DBX26_RS06670	COG2814	Major facilitator Superfamily
DBX26_RS06700	COG4145	pantothenate transmembrane transporter activity
DBX26_RS06705	COG3924	membrane
DBX26_RS06725	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
DBX26_RS06735	COG1349	DNA-binding transcription factor activity
DBX26_RS06740	COG0561	phosphatase activity
DBX26_RS06755	COG0579	oxidoreductase
DBX26_RS06785	COG4638	Rieske (2fe-2S)
DBX26_RS06790	COG0583	DNA-binding transcription factor activity
DBX26_RS06795	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DBX26_RS06910	COG1953	Uracil, thiamine, allantoin
DBX26_RS06925	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DBX26_RS06940	COG2059	Chromate
DBX26_RS06945	COG2059	Chromate
DBX26_RS06975	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DBX26_RS06985	COG1414	Transcriptional regulator
DBX26_RS06995	COG0400	carboxylic ester hydrolase activity
DBX26_RS07005	COG0784	Response regulator, receiver
DBX26_RS07005	COG2198	Histidine kinase
DBX26_RS07005	COG5002	protein histidine kinase activity
DBX26_RS07015	COG0559	Belongs to the binding-protein-dependent transport system permease family
DBX26_RS07035	COG0829	nickel cation binding
DBX26_RS07040	COG0831	urea catabolic process
DBX26_RS07045	COG0832	Belongs to the urease beta subunit family
DBX26_RS07050	COG0804	urea catabolic process
DBX26_RS07060	COG0830	nickel cation binding
DBX26_RS07065	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
DBX26_RS07075	COG0471	metal ion transport
DBX26_RS07080	COG4191	Histidine kinase
DBX26_RS07080	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DBX26_RS07100	COG0814	amino acid
DBX26_RS07120	COG1132	(ABC) transporter
DBX26_RS07125	COG1132	(ABC) transporter
DBX26_RS07140	COG0443	Heat shock 70 kDa protein
DBX26_RS07145	COG0443	Heat shock 70 kDa protein
DBX26_RS07180	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DBX26_RS07185	COG1643	Atp-dependent helicase
DBX26_RS07200	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DBX26_RS07210	COG1793	dna ligase
DBX26_RS07220	COG0534	Mate efflux family protein
DBX26_RS07225	COG0307	riboflavin synthase, alpha
DBX26_RS07235	COG3001	Fructosamine kinase
DBX26_RS07245	COG3706	GGDEF domain
DBX26_RS07255	COG0791	NLP P60 protein
DBX26_RS07260	COG0840	transmembrane signaling receptor activity
DBX26_RS07275	COG3148	PFAM DTW domain containing protein
DBX26_RS07280	COG1940	carbohydrate kinase activity
DBX26_RS07295	COG0303	'Molybdopterin
DBX26_RS07305	COG3842	ATPase activity
DBX26_RS07320	COG2204	response regulator
DBX26_RS07325	COG4191	Histidine kinase
DBX26_RS07335	COG0488	(ABC) transporter
DBX26_RS07340	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DBX26_RS07370	COG0243	molybdopterin cofactor binding
DBX26_RS07370	COG3383	formate dehydrogenase (NAD+) activity
DBX26_RS07375	COG0437	4 iron, 4 sulfur cluster binding
DBX26_RS07390	COG0110	maltose O-acetyltransferase activity
DBX26_RS07395	COG2207	Transcriptional regulator
DBX26_RS07400	COG0534	Mate efflux family protein
DBX26_RS07405	COG0004	ammonium transporteR
DBX26_RS07410	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DBX26_RS07415	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
DBX26_RS07425	COG1177	transmembrane transport
DBX26_RS07435	COG3842	ATPase activity
DBX26_RS07450	COG0037	tRNA processing
DBX26_RS07455	COG0589	response to stress
DBX26_RS07460	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DBX26_RS07475	COG2217	Heavy metal translocating P-type atpase
DBX26_RS07485	COG2010	Cytochrome c
DBX26_RS07500	COG3278	Belongs to the heme-copper respiratory oxidase family
DBX26_RS07515	COG0784	Response regulator, receiver
DBX26_RS07515	COG2205	protein histidine kinase activity
DBX26_RS07590	COG0544	peptidyl-prolyl cis-trans isomerase activity
DBX26_RS07625	COG3120	sequence-specific DNA binding
DBX26_RS07630	COG1067	ATP-dependent peptidase activity
DBX26_RS07635	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DBX26_RS07650	COG0488	(ABC) transporter
DBX26_RS07660	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DBX26_RS07660	COG0116	Belongs to the methyltransferase superfamily
DBX26_RS07670	COG0167	dihydroorotate dehydrogenase activity
DBX26_RS07675	COG2902	Dehydrogenase
DBX26_RS07685	COG0308	aminopeptidase N
DBX26_RS07700	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
DBX26_RS07705	COG1956	GAF domain-containing protein
DBX26_RS07710	COG1132	(ABC) transporter
DBX26_RS07715	COG2995	paraquat-inducible protein a
DBX26_RS07720	COG3008	intermembrane lipid transfer
DBX26_RS07725	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
DBX26_RS07725	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DBX26_RS07745	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DBX26_RS07750	COG1666	GTP binding
DBX26_RS07765	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DBX26_RS07770	COG4597	amino acid ABC transporter
DBX26_RS07775	COG0765	amino acid transport
DBX26_RS07780	COG1126	abc transporter atp-binding protein
DBX26_RS07785	COG0670	Belongs to the BI1 family
DBX26_RS07795	COG2920	part of a sulfur-relay system
DBX26_RS07800	COG1254	Belongs to the acylphosphatase family
DBX26_RS07805	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DBX26_RS07820	COG2885	chlorophyll binding
DBX26_RS07830	COG3706	GGDEF domain
DBX26_RS07840	COG0602	queuosine metabolic process
DBX26_RS07845	COG0561	phosphatase activity
DBX26_RS07855	COG0110	maltose O-acetyltransferase activity
DBX26_RS07880	COG5001	Diguanylate cyclase
DBX26_RS07900	COG1051	belongs to the nudix hydrolase family
DBX26_RS07915	COG2828	Protein conserved in bacteria
DBX26_RS07925	COG0372	Belongs to the citrate synthase family
DBX26_RS07930	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
DBX26_RS07960	COG0730	response to heat
DBX26_RS07965	COG2358	TRAP transporter, solute receptor (TAXI family
DBX26_RS07970	COG1012	belongs to the aldehyde dehydrogenase family
DBX26_RS07975	COG3284	Transcriptional regulator
DBX26_RS07985	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
DBX26_RS07990	COG0363	glucosamine-6-phosphate deaminase activity
DBX26_RS07995	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DBX26_RS08005	COG4774	siderophore transport
DBX26_RS08010	COG4565	transcriptional regulatory protein
DBX26_RS08015	COG3290	protein histidine kinase activity
DBX26_RS08030	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DBX26_RS08045	COG0527	aspartate kinase activity
DBX26_RS08055	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DBX26_RS08060	COG0456	acetyltransferase
DBX26_RS08070	COG4176	ABC-type proline glycine betaine transport system permease component
DBX26_RS08075	COG2113	Glycine betaine
DBX26_RS08095	COG4221	oxidoreductase activity
DBX26_RS08105	COG0745	RESPONSE REGULATOR receiver
DBX26_RS08110	COG0642	Histidine kinase
DBX26_RS08115	COG1368	sulfuric ester hydrolase activity
DBX26_RS08135	COG1404	Belongs to the peptidase S8 family
DBX26_RS08155	COG1115	amino acid carrier protein
DBX26_RS08170	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DBX26_RS08175	COG1280	lysine exporter protein (LysE YggA)
DBX26_RS08180	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
DBX26_RS08185	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DBX26_RS08205	COG1560	Kdo2-lipid A biosynthetic process
DBX26_RS08215	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
DBX26_RS08220	COG3063	Type IV pilus biogenesis stability protein PilW
DBX26_RS08250	COG2315	Protein conserved in bacteria
DBX26_RS08255	COG1846	Transcriptional regulator
DBX26_RS08260	COG0697	spore germination
DBX26_RS08265	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DBX26_RS08270	COG1012	belongs to the aldehyde dehydrogenase family
DBX26_RS08275	COG2957	Belongs to the agmatine deiminase family
DBX26_RS08285	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DBX26_RS08290	COG1012	belongs to the aldehyde dehydrogenase family
DBX26_RS08295	COG1917	Cupin 2, conserved barrel domain protein
DBX26_RS08295	COG1396	sequence-specific DNA binding
DBX26_RS08300	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DBX26_RS08305	COG0174	glutamine synthetase
DBX26_RS08310	COG1757	Na H antiporter
DBX26_RS08330	COG2824	Alkylphosphonate utilization operon protein PhnA
DBX26_RS08335	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DBX26_RS08370	COG0346	lactoylglutathione lyase activity
DBX26_RS08400	COG1794	racemase activity, acting on amino acids and derivatives
DBX26_RS08425	COG0724	RNA recognition motif
DBX26_RS08455	COG0745	RESPONSE REGULATOR receiver
DBX26_RS08460	COG5002	protein histidine kinase activity
DBX26_RS08460	COG5000	phosphorelay sensor kinase activity
DBX26_RS08485	COG1454	alcohol dehydrogenase
DBX26_RS08490	COG2610	gluconate transmembrane transporter activity
DBX26_RS08500	COG3718	enzyme involved in inositol metabolism
DBX26_RS08505	COG0673	inositol 2-dehydrogenase activity
DBX26_RS08510	COG0477	Major facilitator Superfamily
DBX26_RS08510	COG2814	Major facilitator Superfamily
DBX26_RS08515	COG1082	Xylose isomerase domain protein TIM barrel
DBX26_RS08525	COG1082	Xylose isomerase domain protein TIM barrel
DBX26_RS08535	COG1012	belongs to the aldehyde dehydrogenase family
DBX26_RS08535	COG1454	alcohol dehydrogenase
DBX26_RS08540	COG3962	Belongs to the TPP enzyme family
DBX26_RS08545	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DBX26_RS08560	COG2999	glutathione oxidoreductase activity
DBX26_RS08585	COG2814	Major facilitator Superfamily
DBX26_RS08585	COG0477	Major facilitator Superfamily
DBX26_RS08590	COG0673	inositol 2-dehydrogenase activity
DBX26_RS08595	COG1082	Xylose isomerase domain protein TIM barrel
DBX26_RS08615	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
DBX26_RS08615	COG2885	chlorophyll binding
DBX26_RS08635	COG2205	protein histidine kinase activity
DBX26_RS08635	COG3850	Histidine kinase
DBX26_RS08635	COG3437	response regulator, receiver
DBX26_RS08635	COG4999	Histidine kinase
DBX26_RS08680	COG3206	protein involved in exopolysaccharide biosynthesis
DBX26_RS08680	COG0489	protein tyrosine kinase activity
DBX26_RS08685	COG0297	glycogen (starch) synthase activity
DBX26_RS08695	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DBX26_RS08710	COG5492	domain, Protein
DBX26_RS08795	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DBX26_RS08805	COG3768	UPF0283 membrane protein
DBX26_RS08810	COG3106	COG3106 Predicted ATPase
DBX26_RS08840	COG0814	amino acid
DBX26_RS08845	COG1760	l-serine dehydratase
DBX26_RS08850	COG0720	synthase
DBX26_RS08855	COG0017	Asparaginyl-tRNA synthetase
DBX26_RS08865	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DBX26_RS08880	COG1448	Aminotransferase
DBX26_RS08895	COG2176	DNA-directed DNA polymerase activity
DBX26_RS08900	COG0840	transmembrane signaling receptor activity
DBX26_RS08905	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DBX26_RS08910	COG1846	Transcriptional regulator
DBX26_RS08935	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
DBX26_RS08950	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DBX26_RS08955	COG3108	Peptidase M15
DBX26_RS08960	COG2989	Protein conserved in bacteria
DBX26_RS08985	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DBX26_RS09000	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DBX26_RS09005	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DBX26_RS09020	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DBX26_RS09050	COG0019	diaminopimelate decarboxylase activity
DBX26_RS09095	COG0322	excinuclease ABC activity
DBX26_RS09100	COG2197	response regulator
DBX26_RS09105	COG0417	DNA replication proofreading
DBX26_RS09115	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DBX26_RS09120	COG3099	Belongs to the UPF0263 family
DBX26_RS09125	COG1187	pseudouridine synthase activity
DBX26_RS09135	COG0009	L-threonylcarbamoyladenylate synthase
DBX26_RS09140	COG0613	PHP domain protein
DBX26_RS09150	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DBX26_RS09155	COG0512	Glutamine amidotransferase of anthranilate synthase
DBX26_RS09160	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DBX26_RS09165	COG0134	indole-3-glycerol-phosphate synthase activity
DBX26_RS09165	COG0135	phosphoribosylanthranilate isomerase activity
DBX26_RS09170	COG0133	tryptophan synthase activity
DBX26_RS09175	COG0159	tryptophan synthase activity
DBX26_RS09180	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DBX26_RS09185	COG0318	PFAM AMP-dependent synthetase and ligase
DBX26_RS09190	COG1301	dicarboxylic acid transport
DBX26_RS09220	COG2350	Protein conserved in bacteria
DBX26_RS09230	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DBX26_RS09235	COG0583	DNA-binding transcription factor activity
DBX26_RS09250	COG5001	Diguanylate cyclase
DBX26_RS09255	COG1032	radical SAM domain protein
DBX26_RS09260	COG0745	RESPONSE REGULATOR receiver
DBX26_RS09265	COG3850	Histidine kinase
DBX26_RS09265	COG5002	protein histidine kinase activity
DBX26_RS09300	COG3118	belongs to the thioredoxin family
DBX26_RS09305	COG4232	protein-disulfide reductase activity
DBX26_RS09315	COG0189	ligase activity
DBX26_RS09320	COG1773	rubredoxin
DBX26_RS09320	COG0426	domain, Protein
DBX26_RS09330	COG2308	Evidence 4 Homologs of previously reported genes of
DBX26_RS09345	COG2307	Protein conserved in bacteria
DBX26_RS09345	COG2308	Evidence 4 Homologs of previously reported genes of
DBX26_RS09380	COG2863	cytochrome
DBX26_RS09385	COG3258	Cytochrome c
DBX26_RS09390	COG2995	paraquat-inducible protein a
DBX26_RS09395	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
DBX26_RS09395	COG3008	intermembrane lipid transfer
DBX26_RS09400	COG3009	Protein conserved in bacteria
DBX26_RS09405	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DBX26_RS09415	COG0463	Glycosyl transferase, family 2
DBX26_RS09430	COG4166	transmembrane transport
DBX26_RS09440	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
DBX26_RS09445	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
DBX26_RS09455	COG0539	negative regulation of cytoplasmic translation
DBX26_RS09460	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
DBX26_RS09465	COG0616	signal peptide processing
DBX26_RS09470	COG1028	Short-chain dehydrogenase reductase Sdr
DBX26_RS09485	COG0587	DNA-directed DNA polymerase activity
DBX26_RS09490	COG1940	carbohydrate kinase activity
DBX26_RS09495	COG0469	pyruvate kinase activity
DBX26_RS09500	COG4667	esterase of the alpha-beta hydrolase superfamily
DBX26_RS09515	COG0733	neurotransmitter:sodium symporter activity
DBX26_RS09530	COG1263	PTS System
DBX26_RS09530	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DBX26_RS09540	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DBX26_RS09540	COG2190	(PTS) system
DBX26_RS09540	COG1263	PTS System
DBX26_RS09545	COG0084	hydrolase, TatD family'
DBX26_RS09550	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DBX26_RS09555	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DBX26_RS09560	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DBX26_RS09590	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DBX26_RS09595	COG0416	fatty acid biosynthetic process
DBX26_RS09605	COG1399	metal-binding, possibly nucleic acid-binding protein
DBX26_RS09610	COG0424	maF-like protein
DBX26_RS09615	COG0564	pseudouridine synthase activity
DBX26_RS09620	COG1530	ribonuclease E activity
DBX26_RS09630	COG0659	secondary active sulfate transmembrane transporter activity
DBX26_RS09635	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DBX26_RS09640	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
DBX26_RS09650	COG0572	uridine kinase
DBX26_RS09655	COG0489	protein tyrosine kinase activity
DBX26_RS09660	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DBX26_RS09660	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DBX26_RS09670	COG2186	Transcriptional regulator
DBX26_RS09675	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
DBX26_RS09680	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
DBX26_RS09685	COG0653	protein targeting
DBX26_RS09690	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DBX26_RS09695	COG2199	diguanylate cyclase activity
DBX26_RS09700	COG0366	Alpha amylase catalytic
DBX26_RS09705	COG1122	ATPase activity
DBX26_RS09710	COG4120	Belongs to the binding-protein-dependent transport system permease family
DBX26_RS09720	COG3092	negative regulation of chromosome organization
DBX26_RS09725	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DBX26_RS09730	COG0857	belongs to the CobB CobQ family
DBX26_RS09730	COG0280	phosphate acetyltransferase
DBX26_RS09735	COG3174	membrane
DBX26_RS09740	COG0435	Glutathione S-transferase
DBX26_RS09750	COG0444	Belongs to the ABC transporter superfamily
DBX26_RS09755	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DBX26_RS09760	COG0601	transmembrane transport
DBX26_RS09770	COG0314	molybdopterin synthase activity
DBX26_RS09775	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
DBX26_RS09780	COG0315	cyclic pyranopterin monophosphate synthase activity
DBX26_RS09785	COG0521	Mo-molybdopterin cofactor biosynthetic process
DBX26_RS09790	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DBX26_RS09795	COG0391	Required for morphogenesis under gluconeogenic growth conditions
DBX26_RS09800	COG2198	Histidine kinase
DBX26_RS09805	COG2204	response regulator
DBX26_RS09810	COG0556	nucleotide-excision repair
DBX26_RS09820	COG4657	Part of a membrane complex involved in electron transport
DBX26_RS09825	COG2878	Part of a membrane complex involved in electron transport
DBX26_RS09830	COG4656	Part of a membrane complex involved in electron transport
DBX26_RS09835	COG4658	electron transport chain
DBX26_RS09840	COG4659	FMN binding
DBX26_RS09845	COG4660	Part of a membrane complex involved in electron transport
DBX26_RS09850	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DBX26_RS09855	COG0346	lactoylglutathione lyase activity
DBX26_RS09865	COG2885	chlorophyll binding
DBX26_RS09870	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DBX26_RS09875	COG2056	Na+-H+ antiporter family
DBX26_RS09885	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
DBX26_RS09900	COG1028	Short-chain dehydrogenase reductase Sdr
DBX26_RS09905	COG1012	belongs to the aldehyde dehydrogenase family
DBX26_RS09905	COG1454	alcohol dehydrogenase
DBX26_RS09910	COG2095	MarC family integral membrane protein
DBX26_RS09915	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DBX26_RS09920	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DBX26_RS09925	COG1757	Na H antiporter
DBX26_RS09940	COG3081	Nucleoid-associated protein
DBX26_RS09945	COG3082	Protein of unknown function (DUF1414)
DBX26_RS09960	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
DBX26_RS09970	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DBX26_RS09975	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DBX26_RS09980	COG1120	ATPase activity
DBX26_RS09985	COG1522	sequence-specific DNA binding
DBX26_RS09990	COG0626	cystathionine gamma-synthase activity
DBX26_RS09995	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DBX26_RS10000	COG0765	amino acid transport
DBX26_RS10010	COG0123	including yeast histone deacetylase and acetoin utilization protein
DBX26_RS10020	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DBX26_RS10025	COG0778	Nitroreductase
DBX26_RS10030	COG1902	pentaerythritol trinitrate reductase activity
DBX26_RS10030	COG0446	pyridine nucleotide-disulphide oxidoreductase
DBX26_RS10035	COG0616	signal peptide processing
DBX26_RS10040	COG0252	asparaginase activity
DBX26_RS10045	COG3139	Protein of unknown function (DUF1315)
DBX26_RS10055	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DBX26_RS10060	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DBX26_RS10070	COG2226	methyltransferase
DBX26_RS10085	COG1785	Belongs to the alkaline phosphatase family
DBX26_RS10090	COG0668	transmembrane transport
DBX26_RS10100	COG2261	transglycosylase associated protein
DBX26_RS10110	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DBX26_RS10115	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DBX26_RS10130	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DBX26_RS10135	COG2832	Protein of unknown function (DUF454)
DBX26_RS10145	COG0745	RESPONSE REGULATOR receiver
DBX26_RS10150	COG0583	DNA-binding transcription factor activity
DBX26_RS10155	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
DBX26_RS10160	COG1286	toxin biosynthetic process
DBX26_RS10165	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
DBX26_RS10170	COG0285	dihydrofolate synthase activity
DBX26_RS10175	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
DBX26_RS10180	COG0101	tRNA pseudouridine synthase activity
DBX26_RS10190	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DBX26_RS10195	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DBX26_RS10200	COG0747	negative chemotaxis
DBX26_RS10205	COG1349	DNA-binding transcription factor activity
DBX26_RS10220	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DBX26_RS10225	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DBX26_RS10225	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
DBX26_RS10230	COG0431	NADPH-dependent FMN reductase
DBX26_RS10245	COG3101	peptidyl-lysine hydroxylation
DBX26_RS10250	COG2860	membrane
DBX26_RS10255	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DBX26_RS10260	COG2890	protein-(glutamine-N5) methyltransferase activity
DBX26_RS10265	COG2840	Smr protein MutS2
DBX26_RS10270	COG2062	phosphohistidine phosphatase, SixA
DBX26_RS10285	COG1024	Enoyl-CoA hydratase
DBX26_RS10285	COG1250	3-hydroxyacyl-CoA dehydrogenase
DBX26_RS10290	COG0183	Belongs to the thiolase family
DBX26_RS10335	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DBX26_RS10340	COG1138	Cytochrome C-type biogenesis protein
DBX26_RS10345	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
DBX26_RS10350	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DBX26_RS10355	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DBX26_RS10360	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DBX26_RS10365	COG4133	protoheme IX ABC transporter activity
DBX26_RS10375	COG0835	chemotaxis
DBX26_RS10385	COG1192	Involved in chromosome partitioning
DBX26_RS10390	COG2201	protein-glutamate methylesterase activity
DBX26_RS10395	COG0643	Histidine kinase
DBX26_RS10395	COG0784	Response regulator, receiver
DBX26_RS10395	COG2198	Histidine kinase
DBX26_RS10400	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
DBX26_RS10440	COG1987	bacterial-type flagellum assembly
DBX26_RS10490	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DBX26_RS10500	COG1677	Flagellar hook-basal body complex protein FliE
DBX26_RS10525	COG1516	flagellar protein fliS
DBX26_RS10535	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
DBX26_RS10540	COG1334	flagellar protein FlaG
DBX26_RS10545	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DBX26_RS10550	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DBX26_RS10560	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DBX26_RS10565	COG2837	iron assimilation
DBX26_RS10590	COG1393	Belongs to the ArsC family
DBX26_RS10595	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DBX26_RS10610	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
DBX26_RS10615	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DBX26_RS10620	COG2716	regulation of RNA biosynthetic process
DBX26_RS10625	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DBX26_RS10640	COG4783	chaperone-mediated protein folding
DBX26_RS10645	COG1393	Belongs to the ArsC family
DBX26_RS10665	COG2233	PERMEase
DBX26_RS10670	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DBX26_RS10675	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
DBX26_RS10680	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DBX26_RS10685	COG0121	glutamine amidotransferase
DBX26_RS10690	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
DBX26_RS10695	COG1960	acyl-CoA dehydrogenase activity
DBX26_RS10715	COG0328	RNA-DNA hybrid ribonuclease activity
DBX26_RS10720	COG2226	methyltransferase
DBX26_RS10725	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DBX26_RS10730	COG1388	LysM domain
DBX26_RS10730	COG0741	lytic transglycosylase activity
DBX26_RS10740	COG3021	interspecies interaction between organisms
DBX26_RS10745	COG0347	Belongs to the P(II) protein family
DBX26_RS10755	COG0037	tRNA processing
DBX26_RS10760	COG0825	malonyl-CoA metabolic process
DBX26_RS10765	COG0587	DNA-directed DNA polymerase activity
DBX26_RS10775	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DBX26_RS10780	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DBX26_RS10790	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DBX26_RS10795	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
DBX26_RS10805	COG0750	zinc metalloprotease
DBX26_RS10810	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
DBX26_RS10815	COG0575	Belongs to the CDS family
DBX26_RS10820	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DBX26_RS10825	COG0233	cytoplasmic translational termination
DBX26_RS10830	COG0528	UMP kinase activity
DBX26_RS10835	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DBX26_RS10840	COG0052	Belongs to the universal ribosomal protein uS2 family
DBX26_RS10845	COG0024	Methionine aminopeptidase
DBX26_RS10850	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
DBX26_RS10860	COG0564	pseudouridine synthase activity
DBX26_RS10890	COG1671	Belongs to the UPF0178 family
DBX26_RS10895	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
DBX26_RS10905	COG0254	rRNA binding
DBX26_RS10910	COG1720	tRNA m6t6A37 methyltransferase activity
DBX26_RS10930	COG0733	neurotransmitter:sodium symporter activity
DBX26_RS10940	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DBX26_RS10945	COG0514	ATP-dependent DNA helicase (RecQ)
DBX26_RS10950	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DBX26_RS10960	COG2991	Protein conserved in bacteria
DBX26_RS10965	COG1477	protein flavinylation
DBX26_RS10970	COG2871	sodium ion transport
DBX26_RS10975	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
DBX26_RS10980	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
DBX26_RS10985	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
DBX26_RS10990	COG1805	sodium ion transport
DBX26_RS10995	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
DBX26_RS11000	COG0271	Belongs to the BolA IbaG family
DBX26_RS11005	COG2813	Specifically methylates the guanine in position
DBX26_RS11030	COG1595	DNA-templated transcription, initiation
DBX26_RS11050	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DBX26_RS11055	COG0693	protein deglycase activity
DBX26_RS11060	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DBX26_RS11065	COG3706	GGDEF domain
DBX26_RS11070	COG2166	iron-sulfur cluster assembly
DBX26_RS11075	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
DBX26_RS11080	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
DBX26_RS11095	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
DBX26_RS11095	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DBX26_RS11100	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DBX26_RS11105	COG1074	ATP-dependent DNA helicase activity
DBX26_RS11115	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
DBX26_RS11120	COG3083	sulfuric ester hydrolase activity
DBX26_RS11135	COG3141	response to X-ray
DBX26_RS11145	COG2171	N-acyltransferase activity
DBX26_RS11150	COG0584	glycerophosphoryl diester phosphodiesterase
DBX26_RS11155	COG2271	Major facilitator Superfamily
DBX26_RS11160	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DBX26_RS11165	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DBX26_RS11170	COG1349	DNA-binding transcription factor activity
DBX26_RS11175	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
DBX26_RS11200	COG1609	Transcriptional regulator
DBX26_RS11205	COG1609	Transcriptional regulator
DBX26_RS11210	COG0583	DNA-binding transcription factor activity
DBX26_RS11280	COG4964	Belongs to the GSP D family
DBX26_RS11310	COG2169	Transcriptional regulator
DBX26_RS11315	COG1022	Amp-dependent synthetase and ligase
DBX26_RS11325	COG0583	DNA-binding transcription factor activity
DBX26_RS11330	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DBX26_RS11335	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
DBX26_RS11345	COG0560	Phosphoserine phosphatase
DBX26_RS11355	COG0813	purine-nucleoside phosphorylase activity
DBX26_RS11360	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
DBX26_RS11365	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
DBX26_RS11370	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
DBX26_RS11375	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DBX26_RS11380	COG0084	hydrolase, TatD family'
DBX26_RS11390	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
DBX26_RS11485	COG3118	belongs to the thioredoxin family
DBX26_RS11500	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
DBX26_RS11505	COG1215	transferase activity, transferring glycosyl groups
DBX26_RS11510	COG1215	transferase activity, transferring glycosyl groups
DBX26_RS11550	COG3344	reverse transcriptase
DBX26_RS11565	COG2194	sulfuric ester hydrolase activity
DBX26_RS11575	COG3436	PFAM IS66 Orf2 family protein
DBX26_RS11595	COG0446	pyridine nucleotide-disulphide oxidoreductase
DBX26_RS11620	COG2003	Belongs to the UPF0758 family
DBX26_RS11645	COG0714	Associated with various cellular activities
DBX26_RS11660	COG0629	single-stranded DNA binding
DBX26_RS11685	COG1136	(ABC) transporter
DBX26_RS11700	COG1309	transcriptional regulator
DBX26_RS11730	COG0681	Belongs to the peptidase S26 family
DBX26_RS11745	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DBX26_RS11795	COG3093	addiction module antidote protein HigA
DBX26_RS11870	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DBX26_RS11905	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
DBX26_RS11920	COG3153	acetyltransferase
DBX26_RS11925	COG3154	lipid carrier protein
DBX26_RS11940	COG0826	peptidase U32
DBX26_RS11945	COG0826	peptidase U32
DBX26_RS11950	COG0534	Mate efflux family protein
DBX26_RS11960	COG1185	polyribonucleotide nucleotidyltransferase activity
DBX26_RS11965	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DBX26_RS11970	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DBX26_RS11975	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DBX26_RS11980	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DBX26_RS11985	COG0195	Participates in both transcription termination and antitermination
DBX26_RS11990	COG0779	Required for maturation of 30S ribosomal subunits
DBX26_RS12005	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DBX26_RS12015	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DBX26_RS12020	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DBX26_RS12025	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
DBX26_RS12030	COG1534	Rna-binding protein
DBX26_RS12035	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DBX26_RS12040	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
DBX26_RS12045	COG2027	D-alanyl-D-alanine carboxypeptidase
DBX26_RS12055	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DBX26_RS12060	COG0739	heme binding
DBX26_RS12070	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DBX26_RS12075	COG0316	Belongs to the HesB IscA family
DBX26_RS12080	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DBX26_RS12085	COG0628	permease
DBX26_RS12090	COG2813	Specifically methylates the guanine in position
DBX26_RS12100	COG0784	Response regulator, receiver
DBX26_RS12100	COG2205	protein histidine kinase activity
DBX26_RS12105	COG0747	negative chemotaxis
DBX26_RS12115	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DBX26_RS12120	COG0444	Belongs to the ABC transporter superfamily
DBX26_RS12125	COG4608	Belongs to the ABC transporter superfamily
DBX26_RS12135	COG2971	BadF BadG BcrA BcrD
DBX26_RS12150	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DBX26_RS12155	COG3842	ATPase activity
DBX26_RS12165	COG1840	ABC-type Fe3 transport system, periplasmic component
DBX26_RS12170	COG0004	ammonium transporteR
DBX26_RS12180	COG3112	Uncharacterised protein family (UPF0231)
DBX26_RS12185	COG3835	regulator
DBX26_RS12190	COG2610	gluconate transmembrane transporter activity
DBX26_RS12195	COG1929	Belongs to the glycerate kinase type-1 family
DBX26_RS12200	COG1049	propionate catabolic process, 2-methylcitrate cycle
DBX26_RS12205	COG1752	Esterase of the alpha-beta hydrolase superfamily
DBX26_RS12210	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DBX26_RS12215	COG1643	Atp-dependent helicase
DBX26_RS12220	COG1489	DNA binding
DBX26_RS12230	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DBX26_RS12240	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DBX26_RS12245	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
DBX26_RS12250	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
DBX26_RS12255	COG0842	Transport permease protein
DBX26_RS12260	COG1131	(ABC) transporter
DBX26_RS12265	COG0659	secondary active sulfate transmembrane transporter activity
DBX26_RS12270	COG0288	reversible hydration of carbon dioxide
DBX26_RS12285	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DBX26_RS12290	COG0508	dehydrogenase complex catalyzes the overall conversion of
DBX26_RS12295	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
DBX26_RS12300	COG2186	Transcriptional regulator
DBX26_RS12315	COG0157	Belongs to the NadC ModD family
DBX26_RS12325	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DBX26_RS12330	COG1459	type II secretion system
DBX26_RS12340	COG0237	dephospho-CoA kinase activity
DBX26_RS12345	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
DBX26_RS12350	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
DBX26_RS12365	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DBX26_RS12370	COG0228	four-way junction DNA binding
DBX26_RS12375	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DBX26_RS12380	COG4137	Cytochrome C assembly protein
DBX26_RS12385	COG4536	flavin adenine dinucleotide binding
DBX26_RS12390	COG1854	S-ribosylhomocysteine lyase activity
DBX26_RS12400	COG2918	glutathione biosynthetic process
DBX26_RS12405	COG0612	Peptidase, M16
DBX26_RS12410	COG1238	metal cluster binding
DBX26_RS12420	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
DBX26_RS12425	COG0511	ligase activity, forming carbon-carbon bonds
DBX26_RS12425	COG5016	pyruvate
DBX26_RS12430	COG3630	sodium ion export across plasma membrane
DBX26_RS12490	COG0527	aspartate kinase activity
DBX26_RS12495	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DBX26_RS12510	COG1546	Belongs to the CinA family
DBX26_RS12515	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DBX26_RS12530	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DBX26_RS12535	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
DBX26_RS12550	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
DBX26_RS12555	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
DBX26_RS12560	COG0148	phosphopyruvate hydratase activity
DBX26_RS12565	COG0504	CTP synthase activity
DBX26_RS12575	COG3956	TIGRFAM MazG family protein
DBX26_RS12580	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DBX26_RS12585	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DBX26_RS12605	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
DBX26_RS12610	COG1381	Involved in DNA repair and RecF pathway recombination
DBX26_RS12615	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DBX26_RS12630	COG0481	GTPase activity
DBX26_RS12635	COG3086	response to oxidative stress
DBX26_RS12650	COG1595	DNA-templated transcription, initiation
DBX26_RS12655	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
DBX26_RS12665	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
DBX26_RS12670	COG0354	folic acid binding
DBX26_RS12685	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DBX26_RS12690	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DBX26_RS12695	COG3079	Belongs to the UPF0149 family
DBX26_RS12700	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
DBX26_RS12710	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DBX26_RS12715	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
DBX26_RS12720	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DBX26_RS12730	COG0583	DNA-binding transcription factor activity
DBX26_RS12735	COG1279	arginine transmembrane transporter activity
DBX26_RS12740	COG0668	transmembrane transport
DBX26_RS12745	COG0191	fructose-bisphosphate aldolase activity
DBX26_RS12750	COG0126	phosphoglycerate kinase activity
DBX26_RS12755	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DBX26_RS12760	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DBX26_RS12770	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DBX26_RS12785	COG2356	endonuclease I
DBX26_RS12790	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DBX26_RS12795	COG0189	ligase activity
DBX26_RS12805	COG1678	Uncharacterized ACR, COG1678
DBX26_RS12810	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DBX26_RS12825	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DBX26_RS12830	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DBX26_RS12835	COG0762	integral membrane protein
DBX26_RS12840	COG1872	DUF167
DBX26_RS12850	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DBX26_RS12855	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DBX26_RS12860	COG2066	Belongs to the glutaminase family
DBX26_RS12880	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
DBX26_RS12885	COG0741	lytic transglycosylase activity
DBX26_RS13000	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
DBX26_RS13005	COG0300	oxidoreductase activity
DBX26_RS13090	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
DBX26_RS13090	COG2213	PTS system mannitol-specific
DBX26_RS13095	COG0246	Mannitol dehydrogenase
DBX26_RS13100	COG3722	fumarate hydratase activity
DBX26_RS13130	COG1028	Short-chain dehydrogenase reductase Sdr
DBX26_RS13145	COG0795	lipopolysaccharide-transporting ATPase activity
DBX26_RS13150	COG0795	lipopolysaccharide-transporting ATPase activity
DBX26_RS13155	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DBX26_RS13160	COG2927	DNA polymerase III (CHI subunit)
DBX26_RS13165	COG0525	valine-tRNA ligase activity
DBX26_RS13195	COG2235	arginine
DBX26_RS13210	COG0540	Belongs to the ATCase OTCase family
DBX26_RS13215	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
DBX26_RS13220	COG0251	oxidation-reduction process
DBX26_RS13225	COG0204	Acyl-transferase
DBX26_RS13230	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DBX26_RS13235	COG5007	Belongs to the BolA IbaG family
DBX26_RS13245	COG2854	intermembrane phospholipid transfer
DBX26_RS13250	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
DBX26_RS13255	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DBX26_RS13260	COG1127	ABC transporter
DBX26_RS13270	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
DBX26_RS13270	COG0517	IMP dehydrogenase activity
DBX26_RS13280	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
DBX26_RS13285	COG1137	ATPase activity
DBX26_RS13295	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DBX26_RS13300	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DBX26_RS13305	COG1660	Displays ATPase and GTPase activities
DBX26_RS13310	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DBX26_RS13315	COG2239	Acts as a magnesium transporter
DBX26_RS13320	COG0312	modulator of DNA gyrase
DBX26_RS13325	COG3028	Belongs to the UPF0307 family
DBX26_RS13330	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DBX26_RS13335	COG0564	pseudouridine synthase activity
DBX26_RS13345	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DBX26_RS13350	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
DBX26_RS13355	COG0312	modulator of DNA gyrase
DBX26_RS13360	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DBX26_RS13365	COG3164	Protein of unknown function
DBX26_RS13375	COG0424	maF-like protein
DBX26_RS13380	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
DBX26_RS13385	COG1792	Involved in formation and maintenance of cell shape
DBX26_RS13390	COG1077	Cell shape determining protein MreB Mrl
DBX26_RS13435	COG1459	type II secretion system
DBX26_RS13440	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DBX26_RS13450	COG3267	Type II secretory pathway component ExeA
DBX26_RS13450	COG3409	Peptidoglycan-binding domain 1 protein
DBX26_RS13475	COG2200	EAL domain
DBX26_RS13475	COG2199	diguanylate cyclase activity
DBX26_RS13480	COG0629	single-stranded DNA binding
DBX26_RS13495	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DBX26_RS13505	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DBX26_RS13515	COG0527	aspartate kinase activity
DBX26_RS13520	COG0646	methionine synthase
DBX26_RS13520	COG1410	methionine synthase
DBX26_RS13545	COG3335	DDE superfamily endonuclease
DBX26_RS13605	COG0175	sulfate reduction
DBX26_RS13610	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DBX26_RS13615	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
DBX26_RS13635	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DBX26_RS13640	COG0735	belongs to the Fur family
DBX26_RS13650	COG0166	Belongs to the GPI family
DBX26_RS13655	COG0432	Pfam Uncharacterised protein family UPF0047
DBX26_RS13660	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DBX26_RS13685	COG2965	DNA replication, synthesis of RNA primer
DBX26_RS13690	COG0360	Binds together with S18 to 16S ribosomal RNA
DBX26_RS13695	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DBX26_RS13700	COG0338	D12 class N6 adenine-specific DNA methyltransferase
DBX26_RS13710	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DBX26_RS13715	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DBX26_RS13745	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
DBX26_RS13755	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
DBX26_RS13755	COG0678	peroxiredoxin activity
DBX26_RS13760	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
DBX26_RS13760	COG0165	Argininosuccinate lyase
DBX26_RS13765	COG0137	argininosuccinate synthase activity
DBX26_RS13770	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DBX26_RS13775	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DBX26_RS13785	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
DBX26_RS13795	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DBX26_RS13800	COG0527	aspartate kinase activity
DBX26_RS13800	COG0460	homoserine dehydrogenase
DBX26_RS13805	COG0626	cystathionine gamma-synthase activity
DBX26_RS13815	COG0281	malic enzyme
DBX26_RS13835	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DBX26_RS13855	COG2923	Belongs to the DsrF TusC family
DBX26_RS13860	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
DBX26_RS13865	COG2964	Protein conserved in bacteria
DBX26_RS13870	COG0545	Peptidyl-prolyl cis-trans isomerase
DBX26_RS13880	COG2900	Belongs to the SlyX family
DBX26_RS13890	COG1047	Peptidyl-prolyl cis-trans
DBX26_RS13905	COG2249	NAD(P)H dehydrogenase (quinone) activity
DBX26_RS13910	COG0488	(ABC) transporter
DBX26_RS13920	COG0429	hydrolase of the alpha beta-hydrolase fold
DBX26_RS13925	COG3089	Belongs to the UPF0270 family
DBX26_RS13930	COG3954	Phosphoribulokinase
DBX26_RS13935	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DBX26_RS13955	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DBX26_RS13960	COG0512	Glutamine amidotransferase of anthranilate synthase
DBX26_RS13965	COG0180	Tryptophanyl-tRNA synthetase
DBX26_RS13970	COG0546	phosphoglycolate phosphatase activity
DBX26_RS13975	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DBX26_RS13980	COG0557	exoribonuclease II activity
DBX26_RS13985	COG1959	2 iron, 2 sulfur cluster binding
DBX26_RS13990	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DBX26_RS13990	COG1017	nitric oxide dioxygenase activity
DBX26_RS13995	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
DBX26_RS14005	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DBX26_RS14010	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
DBX26_RS14015	COG0330	HflC and HflK could
DBX26_RS14020	COG0330	HflC and HflK could
DBX26_RS14025	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DBX26_RS14035	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DBX26_RS14040	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DBX26_RS14045	COG0860	N-Acetylmuramoyl-L-alanine amidase
DBX26_RS14050	COG0802	atpase or kinase
DBX26_RS14055	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DBX26_RS14120	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
DBX26_RS14125	COG1162	GTPase activity
DBX26_RS14135	COG0471	metal ion transport
DBX26_RS14145	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
DBX26_RS14150	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DBX26_RS14160	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DBX26_RS14165	COG1045	serine acetyltransferase
DBX26_RS14170	COG4942	peptidase
DBX26_RS14190	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
DBX26_RS14195	COG1053	succinate dehydrogenase
DBX26_RS14200	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DBX26_RS14220	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DBX26_RS14225	COG1509	lysine 2,3-aminomutase activity
DBX26_RS14230	COG1285	pathogenesis
DBX26_RS14250	COG0534	Mate efflux family protein
DBX26_RS14255	COG0205	6-phosphofructokinase activity
DBX26_RS14265	COG3678	ATP-independent chaperone mediated protein folding
DBX26_RS14270	COG0745	RESPONSE REGULATOR receiver
DBX26_RS14275	COG2205	protein histidine kinase activity
DBX26_RS14280	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
DBX26_RS14285	COG3030	protein affecting phage T7 exclusion by the F plasmid
DBX26_RS14290	COG1027	Aspartate ammonia-lyase
DBX26_RS14295	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
DBX26_RS14300	COG4232	protein-disulfide reductase activity
DBX26_RS14310	COG3263	regulation of cellular component size
DBX26_RS14320	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DBX26_RS14335	COG2198	Histidine kinase
DBX26_RS14335	COG0784	Response regulator, receiver
DBX26_RS14335	COG2205	protein histidine kinase activity
DBX26_RS14340	COG2814	Major facilitator Superfamily
DBX26_RS14355	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DBX26_RS14360	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
DBX26_RS14365	COG0511	ligase activity, forming carbon-carbon bonds
DBX26_RS14370	COG0439	Biotin carboxylase
DBX26_RS14375	COG2264	protein methyltransferase activity
DBX26_RS14380	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DBX26_RS14385	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
DBX26_RS14415	COG3335	DDE superfamily endonuclease
DBX26_RS14470	COG3710	Transcriptional regulator
DBX26_RS14485	COG0138	bifunctional purine biosynthesis protein purh
DBX26_RS14490	COG0151	Belongs to the GarS family
DBX26_RS14505	COG1253	flavin adenine dinucleotide binding
DBX26_RS14510	COG3068	Protein conserved in bacteria
DBX26_RS14520	COG1573	uracil-dna glycosylase
DBX26_RS14525	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
DBX26_RS14530	COG2816	NAD+ diphosphatase activity
DBX26_RS14535	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
DBX26_RS14540	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DBX26_RS14545	COG0085	RNA polymerase activity
DBX26_RS14550	COG0222	ribosome binding
DBX26_RS14555	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DBX26_RS14570	COG0250	Participates in transcription elongation, termination and antitermination
DBX26_RS14575	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DBX26_RS14620	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DBX26_RS14630	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DBX26_RS14705	COG4206	TonB-dependent receptor
DBX26_RS14725	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DBX26_RS14730	COG0534	Mate efflux family protein
DBX26_RS14735	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
DBX26_RS14740	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DBX26_RS14745	COG2937	Belongs to the GPAT DAPAT family
DBX26_RS14750	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
DBX26_RS14755	COG3161	chorismate lyase activity
DBX26_RS14760	COG1580	Controls the rotational direction of flagella during chemotaxis
DBX26_RS14765	COG0705	Rhomboid family
DBX26_RS14785	COG2177	Part of the ABC transporter FtsEX involved in
DBX26_RS14790	COG2884	Cell division ATP-binding protein ftsE
DBX26_RS14795	COG0552	protein localization to endoplasmic reticulum
DBX26_RS14800	COG0742	ribosomal rna small subunit methyltransferase
DBX26_RS14850	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DBX26_RS14855	COG0640	Transcriptional regulator
DBX26_RS14860	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
DBX26_RS14865	COG1280	lysine exporter protein (LysE YggA)
DBX26_RS14870	COG2267	carboxylic ester hydrolase activity
DBX26_RS14875	COG0561	phosphatase activity
DBX26_RS14890	COG3148	PFAM DTW domain containing protein
DBX26_RS14895	COG1011	Hydrolase
DBX26_RS14900	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
DBX26_RS14910	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
DBX26_RS14915	COG0019	diaminopimelate decarboxylase activity
DBX26_RS14925	COG1965	Belongs to the frataxin family
DBX26_RS14930	COG3072	Adenylate cyclase
DBX26_RS14935	COG0181	hydroxymethylbilane synthase activity
DBX26_RS14940	COG1587	Uroporphyrinogen-III synthase
DBX26_RS14945	COG2959	enzyme of heme biosynthesis
DBX26_RS14950	COG3071	HemY protein
DBX26_RS15000	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
DBX26_RS15020	COG3118	belongs to the thioredoxin family
DBX26_RS15025	COG0513	Belongs to the DEAD box helicase family
DBX26_RS15030	COG0248	Ppx GppA phosphatase
DBX26_RS15035	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
DBX26_RS15045	COG0514	ATP-dependent DNA helicase (RecQ)
DBX26_RS15050	COG2962	Rard protein
DBX26_RS15060	COG1280	lysine exporter protein (LysE YggA)
DBX26_RS15065	COG0405	Gamma-glutamyltransferase
DBX26_RS15070	COG0210	DNA helicase
DBX26_RS15080	COG3220	belongs to the UPF0276 family
DBX26_RS15110	COG0006	proline dipeptidase activity
DBX26_RS15110	COG0006	proline dipeptidase activity
DBX26_RS15120	COG2022	thiamine diphosphate biosynthetic process
DBX26_RS15125	COG2104	thiamine diphosphate biosynthetic process
DBX26_RS15130	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DBX26_RS15140	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
DBX26_RS15145	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DBX26_RS15150	COG2132	Multicopper oxidase
DBX26_RS15200	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
DBX26_RS15210	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DBX26_RS15215	COG0408	coproporphyrinogen oxidase activity
DBX26_RS15220	COG0009	L-threonylcarbamoyladenylate synthase
DBX26_RS15225	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DBX26_RS15230	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DBX26_RS15235	COG0551	DNA topoisomerase type I activity
DBX26_RS15240	COG2922	Belongs to the Smg family
DBX26_RS15245	COG0758	DNA mediated transformation
DBX26_RS15265	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DBX26_RS15265	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DBX26_RS15270	COG0569	domain protein
DBX26_RS15275	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DBX26_RS15285	COG1272	protein, Hemolysin III
DBX26_RS15290	COG4326	sporulation control protein
DBX26_RS15300	COG3084	Protein conserved in bacteria
DBX26_RS15310	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DBX26_RS15315	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DBX26_RS15320	COG0204	Acyl-transferase
DBX26_RS15330	COG0606	chelatase, subunit chli
DBX26_RS15340	COG3978	acetolactate synthase activity
DBX26_RS15355	COG0583	DNA-binding transcription factor activity
DBX26_RS15360	COG2814	Major facilitator Superfamily
DBX26_RS15365	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DBX26_RS15370	COG0765	amino acid transport
DBX26_RS15380	COG0355	proton-transporting ATP synthase activity, rotational mechanism
DBX26_RS15385	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DBX26_RS15390	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DBX26_RS15395	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DBX26_RS15400	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DBX26_RS15415	COG0356	it plays a direct role in the translocation of protons across the membrane
DBX26_RS15420	COG3312	ion transport
DBX26_RS15425	COG1475	DNA binding
DBX26_RS15430	COG1192	Involved in chromosome partitioning
DBX26_RS15440	COG0445	tRNA wobble uridine modification
DBX26_RS15445	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
DBX26_RS15455	COG0706	membrane insertase activity
DBX26_RS15465	COG0594	ribonuclease P activity
DBX26_RS15475	COG1126	abc transporter atp-binding protein
DBX26_RS15500	COG0592	DNA-directed DNA polymerase activity
DBX26_RS15505	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DBX26_RS15510	COG0187	DNA topoisomerase II activity
DBX26_RS15515	COG0071	Belongs to the small heat shock protein (HSP20) family
DBX26_RS15520	COG3977	Valine--pyruvate aminotransferase
DBX26_RS15525	COG0366	Alpha amylase catalytic
DBX26_RS15530	COG0751	glycine-tRNA ligase activity
DBX26_RS15540	COG2119	membrane
DBX26_RS15550	COG0425	Belongs to the sulfur carrier protein TusA family
DBX26_RS15565	COG0604	alcohol dehydrogenase
DBX26_RS15570	COG0183	Belongs to the thiolase family
DBX26_RS15575	COG1024	Enoyl-CoA hydratase
DBX26_RS15575	COG1250	3-hydroxyacyl-CoA dehydrogenase
DBX26_RS15580	COG1739	Uncharacterized protein family UPF0029
DBX26_RS15585	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DBX26_RS15625	COG0583	DNA-binding transcription factor activity
DBX26_RS15630	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DBX26_RS15635	COG2960	long-chain fatty acid transporting porin activity
DBX26_RS15640	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DBX26_RS15645	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DBX26_RS15650	COG1309	transcriptional regulator
DBX26_RS15705	COG4166	transmembrane transport
DBX26_RS15710	COG0601	transmembrane transport
DBX26_RS15715	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DBX26_RS15760	COG3550	peptidyl-serine autophosphorylation
DBX26_RS15800	COG3344	reverse transcriptase
DBX26_RS15820	COG5413	integral membrane protein
DBX26_RS15835	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DBX26_RS15840	COG1960	acyl-CoA dehydrogenase activity
DBX26_RS15850	COG0183	Belongs to the thiolase family
DBX26_RS15860	COG1960	acyl-CoA dehydrogenase activity
DBX26_RS15865	COG1024	Enoyl-CoA hydratase
DBX26_RS15880	COG1028	Short-chain dehydrogenase reductase Sdr
DBX26_RS15885	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
DBX26_RS15890	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DBX26_RS15895	COG1845	cytochrome c oxidase, subunit III
DBX26_RS15900	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
DBX26_RS15905	COG0109	protoheme IX farnesyltransferase activity
DBX26_RS15910	COG1902	pentaerythritol trinitrate reductase activity
DBX26_RS15920	COG0531	amino acid
DBX26_RS15925	COG2040	homocysteine
DBX26_RS15940	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
DBX26_RS15965	COG1126	abc transporter atp-binding protein
DBX26_RS15970	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DBX26_RS15975	COG4215	(ABC) transporter
DBX26_RS15980	COG4160	amino acid transport
DBX26_RS15985	COG1115	amino acid carrier protein
DBX26_RS15995	COG0583	DNA-binding transcription factor activity
DBX26_RS16010	COG1404	Belongs to the peptidase S8 family
DBX26_RS16015	COG3949	Membrane
DBX26_RS16025	COG3604	Transcriptional regulator
DBX26_RS16055	COG3383	formate dehydrogenase (NAD+) activity
DBX26_RS16065	COG0543	2 iron, 2 sulfur cluster binding
DBX26_RS16070	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DBX26_RS16070	COG0574	Belongs to the PEP-utilizing enzyme family
DBX26_RS16080	COG0508	dehydrogenase complex catalyzes the overall conversion of
DBX26_RS16085	COG0022	dehydrogenase e1 component
DBX26_RS16085	COG0508	dehydrogenase complex catalyzes the overall conversion of
DBX26_RS16090	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DBX26_RS16105	COG4702	Belongs to the UPF0303 family
DBX26_RS16110	COG0673	inositol 2-dehydrogenase activity
DBX26_RS16115	COG1349	DNA-binding transcription factor activity
DBX26_RS16155	COG0443	Heat shock 70 kDa protein
DBX26_RS16190	COG0814	amino acid
DBX26_RS16200	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DBX26_RS16255	COG0509	glycine decarboxylation via glycine cleavage system
DBX26_RS16260	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DBX26_RS16270	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DBX26_RS16280	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DBX26_RS16295	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DBX26_RS16295	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
DBX26_RS16295	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DBX26_RS16300	COG1105	Belongs to the carbohydrate kinase PfkB family
DBX26_RS16305	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
DBX26_RS16305	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DBX26_RS16310	COG1609	Transcriptional regulator
DBX26_RS16325	COG0765	amino acid transport
DBX26_RS16330	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DBX26_RS16335	COG0765	amino acid transport
DBX26_RS16340	COG1126	abc transporter atp-binding protein
DBX26_RS16350	COG1979	alcohol dehydrogenase
DBX26_RS16355	COG2207	Transcriptional regulator
DBX26_RS16365	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DBX26_RS16370	COG2759	Belongs to the formate--tetrahydrofolate ligase family
DBX26_RS16375	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DBX26_RS16390	COG0546	phosphoglycolate phosphatase activity
DBX26_RS16400	COG0840	transmembrane signaling receptor activity
DBX26_RS16410	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
DBX26_RS16415	COG0513	Belongs to the DEAD box helicase family
DBX26_RS16420	COG4943	cyclic-guanylate-specific phosphodiesterase activity
DBX26_RS16435	COG3038	cytochrome b561
DBX26_RS16440	COG2353	YceI-like domain
DBX26_RS16445	COG2116	formate transmembrane transporter activity
DBX26_RS16450	COG0583	DNA-binding transcription factor activity
DBX26_RS16460	COG3593	DNA synthesis involved in DNA repair
DBX26_RS16465	COG0737	Belongs to the 5'-nucleotidase family
DBX26_RS16485	COG2267	carboxylic ester hydrolase activity
DBX26_RS16490	COG2067	long-chain fatty acid transport protein
DBX26_RS16505	COG2050	protein possibly involved in aromatic compounds catabolism
DBX26_RS16525	COG1324	tolerance protein
DBX26_RS16550	COG3300	MHYT domain
DBX26_RS16550	COG5001	Diguanylate cyclase
DBX26_RS16555	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
DBX26_RS16565	COG4181	ATPase activity
DBX26_RS16570	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
DBX26_RS16580	COG1984	allophanate hydrolase subunit 2
DBX26_RS16585	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
DBX26_RS16590	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
DBX26_RS16595	COG3447	MASE1 domain protein
DBX26_RS16595	COG5001	Diguanylate cyclase
DBX26_RS16595	COG5002	protein histidine kinase activity
DBX26_RS16610	COG0583	DNA-binding transcription factor activity
DBX26_RS16615	COG0045	succinate-CoA ligase (ADP-forming) activity
DBX26_RS16615	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DBX26_RS16615	COG1042	CoA-binding domain protein
DBX26_RS16625	COG1181	Belongs to the D-alanine--D-alanine ligase family
DBX26_RS16635	COG0023	Translation Initiation Factor
DBX26_RS16660	COG3140	Belongs to the UPF0181 family
DBX26_RS16675	COG0745	RESPONSE REGULATOR receiver
DBX26_RS16685	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
DBX26_RS16690	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
DBX26_RS16705	COG3706	GGDEF domain
DBX26_RS16710	COG3706	GGDEF domain
DBX26_RS16710	COG2203	Gaf domain
DBX26_RS16710	COG4251	negative regulation of phosphorylation
DBX26_RS16710	COG5001	Diguanylate cyclase
DBX26_RS16720	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
DBX26_RS16725	COG4149	molybdate abc transporter
DBX26_RS16730	COG0725	ABC transporter, periplasmic molybdate-binding protein
DBX26_RS16735	COG1492	cobalamin metabolic process
DBX26_RS16745	COG0189	ligase activity
DBX26_RS16745	COG4067	protein conserved in archaea
DBX26_RS16755	COG2207	Transcriptional regulator
DBX26_RS16760	COG0534	Mate efflux family protein
DBX26_RS16765	COG0602	queuosine metabolic process
DBX26_RS16770	COG1328	CTP reductase activity
DBX26_RS16815	COG0446	pyridine nucleotide-disulphide oxidoreductase
DBX26_RS16825	COG0583	DNA-binding transcription factor activity
DBX26_RS16850	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DBX26_RS16855	COG3118	belongs to the thioredoxin family
DBX26_RS16880	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
DBX26_RS16900	COG2116	formate transmembrane transporter activity
DBX26_RS16910	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DBX26_RS16915	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DBX26_RS16920	COG5001	Diguanylate cyclase
DBX26_RS16945	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DBX26_RS16945	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
DBX26_RS16995	COG0277	FAD linked oxidase domain protein
DBX26_RS17000	COG0583	DNA-binding transcription factor activity
DBX26_RS17010	COG2425	protein containing a von Willebrand factor type A (vWA) domain
DBX26_RS17025	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
DBX26_RS17040	COG3040	lipid binding
DBX26_RS17050	COG0702	epimerase
DBX26_RS17055	COG1733	regulation of RNA biosynthetic process
DBX26_RS17075	COG0419	ATPase involved in DNA repair
DBX26_RS17080	COG0420	3'-5' exonuclease activity
DBX26_RS17085	COG2130	NADP-dependent
DBX26_RS17090	COG1846	Transcriptional regulator
DBX26_RS17100	COG0745	RESPONSE REGULATOR receiver
DBX26_RS17105	COG2205	protein histidine kinase activity
DBX26_RS17120	COG4172	Belongs to the ABC transporter superfamily
DBX26_RS17125	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DBX26_RS17130	COG0601	transmembrane transport
DBX26_RS17135	COG4166	transmembrane transport
DBX26_RS17150	COG0765	amino acid transport
DBX26_RS17155	COG0765	amino acid transport
DBX26_RS17165	COG1737	Transcriptional regulator
DBX26_RS17170	COG1028	Short-chain dehydrogenase reductase Sdr
DBX26_RS17175	COG4670	ketone body catabolic process
DBX26_RS17195	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
DBX26_RS17230	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
DBX26_RS17235	COG0069	glutamate synthase activity
DBX26_RS17250	COG3290	protein histidine kinase activity
DBX26_RS17260	COG0471	metal ion transport
DBX26_RS17305	COG2197	response regulator
DBX26_RS17315	COG3706	GGDEF domain
DBX26_RS17325	COG5001	Diguanylate cyclase
DBX26_RS17325	COG3300	MHYT domain
DBX26_RS17330	COG2205	protein histidine kinase activity
DBX26_RS17330	COG0784	Response regulator, receiver
DBX26_RS17335	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
DBX26_RS17345	COG1214	PFAM Peptidase M22, glycoprotease
DBX26_RS17345	COG0456	acetyltransferase
DBX26_RS17355	COG3069	C4-dicarboxylate transmembrane transporter activity
DBX26_RS17360	COG1704	LemA family
DBX26_RS17365	COG0501	Belongs to the peptidase M48B family
DBX26_RS17375	COG2223	nitrite transmembrane transporter activity
DBX26_RS17385	COG1597	lipid kinase activity
DBX26_RS17420	COG0714	Associated with various cellular activities
DBX26_RS17425	COG0641	radical SAM
DBX26_RS17430	COG3119	arylsulfatase activity
DBX26_RS17450	COG2198	Histidine kinase
DBX26_RS17450	COG0784	Response regulator, receiver
DBX26_RS17450	COG2205	protein histidine kinase activity
DBX26_RS17455	COG1879	ABC-type sugar transport system periplasmic component
DBX26_RS17460	COG1803	Methylglyoxal synthase
DBX26_RS17465	COG0210	DNA helicase
DBX26_RS17470	COG1289	transmembrane transporter activity
DBX26_RS17485	COG0789	Transcriptional regulator
DBX26_RS17495	COG1609	Transcriptional regulator
DBX26_RS17500	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DBX26_RS17505	COG1879	ABC-type sugar transport system periplasmic component
DBX26_RS17510	COG1172	Belongs to the binding-protein-dependent transport system permease family
DBX26_RS17515	COG1129	ABC transporter
DBX26_RS17520	COG1869	D-ribose catabolic process
DBX26_RS17525	COG5001	Diguanylate cyclase
DBX26_RS17585	COG4658	electron transport chain
DBX26_RS17590	COG4656	Part of a membrane complex involved in electron transport
DBX26_RS17595	COG2878	Part of a membrane complex involved in electron transport
DBX26_RS17600	COG4657	Part of a membrane complex involved in electron transport
DBX26_RS17605	COG4191	Histidine kinase
DBX26_RS17605	COG0784	Response regulator, receiver
DBX26_RS17630	COG1278	Cold shock
DBX26_RS17635	COG4628	conserved protein (DUF2132)
DBX26_RS17645	COG1280	lysine exporter protein (LysE YggA)
DBX26_RS17650	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
DBX26_RS17665	COG3265	gluconokinase activity
DBX26_RS17745	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
DBX26_RS17795	COG0243	molybdopterin cofactor binding
DBX26_RS17800	COG1648	precorrin-2 dehydrogenase activity
DBX26_RS17800	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DBX26_RS17805	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DBX26_RS17815	COG2223	nitrite transmembrane transporter activity
DBX26_RS17820	COG0515	serine threonine protein kinase
DBX26_RS17820	COG2815	serine threonine protein kinase
DBX26_RS17825	COG2197	response regulator
DBX26_RS17845	COG3300	MHYT domain
DBX26_RS17845	COG5001	Diguanylate cyclase
DBX26_RS17855	COG0330	HflC and HflK could
DBX26_RS17860	COG4175	Glycine betaine
DBX26_RS17860	COG0517	IMP dehydrogenase activity
DBX26_RS17865	COG4176	ABC-type proline glycine betaine transport system permease component
DBX26_RS17880	COG1012	belongs to the aldehyde dehydrogenase family
DBX26_RS17885	COG1309	transcriptional regulator
DBX26_RS17890	COG1028	Short-chain dehydrogenase reductase Sdr
DBX26_RS17905	COG1024	Enoyl-CoA hydratase
DBX26_RS17910	COG1960	acyl-CoA dehydrogenase activity
DBX26_RS17920	COG0183	Belongs to the thiolase family
DBX26_RS17930	COG1960	acyl-CoA dehydrogenase activity
DBX26_RS17935	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DBX26_RS17945	COG4770	biotin carboxylase activity
DBX26_RS17980	COG4948	Mandelate Racemase Muconate Lactonizing
DBX26_RS18005	COG0583	DNA-binding transcription factor activity
DBX26_RS18015	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
DBX26_RS18015	COG3264	Mechanosensitive ion channel
DBX26_RS18025	COG3474	cytochrome
DBX26_RS18090	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DBX26_RS18090	COG2205	protein histidine kinase activity
DBX26_RS18105	COG2814	Major facilitator Superfamily
DBX26_RS18130	COG1355	regulation of microtubule-based process
DBX26_RS18155	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DBX26_RS18155	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DBX26_RS18160	COG3835	regulator
DBX26_RS18165	COG1929	Belongs to the glycerate kinase type-1 family
DBX26_RS18170	COG2084	Dehydrogenase
DBX26_RS18180	COG4948	Mandelate Racemase Muconate Lactonizing
DBX26_RS18195	COG2271	Major facilitator Superfamily
DBX26_RS18210	COG2721	sulfolactate sulfo-lyase activity
DBX26_RS18215	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DBX26_RS18220	COG0656	L-ascorbic acid biosynthetic process
DBX26_RS18225	COG0402	S-adenosylhomocysteine deaminase activity
DBX26_RS18230	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DBX26_RS18255	COG1028	Short-chain dehydrogenase reductase Sdr
DBX26_RS18295	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DBX26_RS18300	COG1132	(ABC) transporter
DBX26_RS18305	COG1132	(ABC) transporter
DBX26_RS18350	COG0583	DNA-binding transcription factor activity
DBX26_RS18355	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
DBX26_RS18380	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DBX26_RS18395	COG1252	NADH dehydrogenase
DBX26_RS18420	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
DBX26_RS18425	COG2159	amidohydrolase
DBX26_RS18430	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DBX26_RS18435	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
DBX26_RS18460	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
DBX26_RS18465	COG0583	DNA-binding transcription factor activity
DBX26_RS18480	COG0667	Aldo Keto reductase
DBX26_RS18485	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DBX26_RS18495	COG0583	DNA-binding transcription factor activity
DBX26_RS18515	COG0579	oxidoreductase
DBX26_RS18540	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DBX26_RS18550	COG1757	Na H antiporter
DBX26_RS18555	COG2423	ornithine cyclodeaminase activity
DBX26_RS18565	COG4974	Belongs to the 'phage' integrase family
DBX26_RS18580	COG1349	DNA-binding transcription factor activity
DBX26_RS18585	COG0561	phosphatase activity
DBX26_RS18590	COG1609	Transcriptional regulator
DBX26_RS18595	COG0110	maltose O-acetyltransferase activity
DBX26_RS18610	COG0583	DNA-binding transcription factor activity
DBX26_RS18640	COG3451	type IV secretory pathway VirB4
DBX26_RS18665	COG3504	Conjugal transfer protein
DBX26_RS18705	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
DBX26_RS18710	COG2731	YhcH YjgK YiaL family protein
DBX26_RS18715	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
DBX26_RS18720	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DBX26_RS18725	COG1414	Transcriptional regulator
DBX26_RS18730	COG0800	Aldolase
DBX26_RS18735	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DBX26_RS18740	COG1917	Cupin 2, conserved barrel domain protein
DBX26_RS18760	COG3181	Tripartite tricarboxylate transporter family receptor
DBX26_RS18815	COG2186	Transcriptional regulator
DBX26_RS18820	COG2186	Transcriptional regulator
DBX26_RS18825	COG0517	IMP dehydrogenase activity
DBX26_RS18830	COG2176	DNA-directed DNA polymerase activity
DBX26_RS18840	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DBX26_RS18895	COG2003	Belongs to the UPF0758 family
DBX26_RS18915	COG1278	Cold shock
DBX26_RS18935	COG0330	HflC and HflK could
DBX26_RS18965	COG3706	GGDEF domain
DBX26_RS18970	COG3706	GGDEF domain
DBX26_RS18975	COG3706	GGDEF domain
DBX26_RS18985	COG1473	amidohydrolase
DBX26_RS18990	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
DBX26_RS18995	COG2084	Dehydrogenase
DBX26_RS19005	COG4580	involved in the transport of maltose and maltodextrins
DBX26_RS19010	COG1874	Beta-galactosidase
DBX26_RS19020	COG3833	ABC-type maltose transport systems, permease component
DBX26_RS19025	COG1175	transmembrane transport
DBX26_RS19030	COG2182	Extracellular solute-binding protein
DBX26_RS19050	COG0667	Aldo Keto reductase
DBX26_RS19080	COG0582	viral genome integration into host DNA
DBX26_RS19090	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DBX26_RS19090	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DBX26_RS19095	COG4989	oxidoreductase activity
DBX26_RS19110	COG0038	chloride channel
DBX26_RS19130	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DBX26_RS19140	COG2897	thiosulfate sulfurtransferase activity
DBX26_RS19150	COG2358	TRAP transporter, solute receptor (TAXI family
DBX26_RS19160	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DBX26_RS19165	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DBX26_RS19170	COG0840	transmembrane signaling receptor activity
DBX26_RS19175	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DBX26_RS19190	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DBX26_RS19200	COG0840	transmembrane signaling receptor activity
DBX26_RS19220	COG2195	Cleaves the N-terminal amino acid of tripeptides
DBX26_RS19235	COG2197	response regulator
DBX26_RS19240	COG3850	Histidine kinase
DBX26_RS19245	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
DBX26_RS19255	COG0243	molybdopterin cofactor binding
DBX26_RS19285	COG0183	Belongs to the thiolase family
DBX26_RS19295	COG1280	lysine exporter protein (LysE YggA)
DBX26_RS19300	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DBX26_RS19305	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DBX26_RS19360	COG2205	protein histidine kinase activity
DBX26_RS19360	COG0784	Response regulator, receiver
DBX26_RS19365	COG1879	ABC-type sugar transport system periplasmic component
DBX26_RS19395	COG0673	inositol 2-dehydrogenase activity
DBX26_RS19420	COG1522	sequence-specific DNA binding
DBX26_RS19425	COG0531	amino acid
DBX26_RS19440	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
DBX26_RS19445	COG2239	Acts as a magnesium transporter
DBX26_RS19450	COG1418	mRNA catabolic process
DBX26_RS19470	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DBX26_RS19485	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DBX26_RS19500	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
DBX26_RS19505	COG2194	sulfuric ester hydrolase activity
DBX26_RS19510	COG0673	inositol 2-dehydrogenase activity
DBX26_RS19515	COG3304	Inner membrane component domain
DBX26_RS19530	COG4667	esterase of the alpha-beta hydrolase superfamily
DBX26_RS19535	COG1741	Belongs to the pirin family
DBX26_RS19540	COG1278	Cold shock
DBX26_RS19555	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DBX26_RS19560	COG0678	peroxiredoxin activity
DBX26_RS19560	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
DBX26_RS19575	COG0625	glutathione transferase activity
DBX26_RS19580	COG1028	Short-chain dehydrogenase reductase Sdr
DBX26_RS19615	COG0513	Belongs to the DEAD box helicase family
DBX26_RS19625	COG0583	DNA-binding transcription factor activity
DBX26_RS19640	COG1028	Short-chain dehydrogenase reductase Sdr
DBX26_RS19650	COG2723	6-phospho-beta-galactosidase activity
DBX26_RS19655	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DBX26_RS19655	COG1263	PTS System
DBX26_RS19655	COG2190	(PTS) system
DBX26_RS19660	COG2723	6-phospho-beta-galactosidase activity
DBX26_RS19665	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DBX26_RS19670	COG1609	Transcriptional regulator
DBX26_RS19675	COG0006	proline dipeptidase activity
DBX26_RS19680	COG3608	succinylglutamate desuccinylase aspartoacylase
DBX26_RS19685	COG1522	sequence-specific DNA binding
DBX26_RS19690	COG1012	belongs to the aldehyde dehydrogenase family
DBX26_RS19695	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DBX26_RS19700	COG3122	Protein conserved in bacteria
DBX26_RS19705	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
DBX26_RS19710	COG2986	histidine ammonia-lyase
DBX26_RS19740	COG1309	transcriptional regulator
DBX26_RS19775	COG2233	PERMEase
DBX26_RS19785	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DBX26_RS19805	COG1278	Cold shock
DBX26_RS19810	COG0557	exoribonuclease II activity
DBX26_RS19825	COG2188	Transcriptional regulator
DBX26_RS19835	COG0697	spore germination
DBX26_RS19845	COG0583	DNA-binding transcription factor activity
DBX26_RS19850	COG2814	Major facilitator Superfamily
DBX26_RS19855	COG4566	intracellular signal transduction
DBX26_RS19860	COG4191	Histidine kinase
DBX26_RS19865	COG0318	PFAM AMP-dependent synthetase and ligase
DBX26_RS19870	COG0659	secondary active sulfate transmembrane transporter activity
DBX26_RS19875	COG0583	DNA-binding transcription factor activity
DBX26_RS19880	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DBX26_RS19885	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
DBX26_RS19890	COG0574	Belongs to the PEP-utilizing enzyme family
DBX26_RS19890	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DBX26_RS19905	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DBX26_RS19910	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
DBX26_RS19940	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DBX26_RS19970	COG3842	ATPase activity
DBX26_RS20000	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DBX26_RS20060	COG1342	Belongs to the UPF0251 family
DBX26_RS20065	COG3015	lipoprotein NlpE involved in copper resistance
DBX26_RS20070	COG0583	DNA-binding transcription factor activity
DBX26_RS20075	COG0697	spore germination
DBX26_RS20090	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DBX26_RS20100	COG1335	isochorismatase
DBX26_RS20115	COG0531	amino acid
DBX26_RS20120	COG4302	ethanolamine ammonia-lyase activity
DBX26_RS20125	COG4303	Ethanolamine ammonia lyase large subunit
DBX26_RS20145	COG1280	lysine exporter protein (LysE YggA)
DBX26_RS20150	COG0459	protein refolding
DBX26_RS20155	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DBX26_RS20160	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DBX26_RS20185	COG1304	FMN binding
DBX26_RS20205	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DBX26_RS20225	COG1760	l-serine dehydratase
DBX26_RS20240	COG2866	Carboxypeptidase
DBX26_RS20245	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DBX26_RS20265	COG3842	ATPase activity
DBX26_RS20275	COG1840	ABC-type Fe3 transport system, periplasmic component
DBX26_RS20285	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DBX26_RS20305	COG3240	lipase activity
DBX26_RS20310	COG1538	Outer membrane efflux protein
DBX26_RS20315	COG1136	(ABC) transporter
DBX26_RS20315	COG0577	efflux transmembrane transporter activity
DBX26_RS20320	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DBX26_RS20335	COG1011	Hydrolase
DBX26_RS20375	COG3152	Membrane
DBX26_RS20385	COG1765	OsmC-like protein
DBX26_RS20390	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DBX26_RS20390	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DBX26_RS20405	COG3046	protein related to deoxyribodipyrimidine photolyase
DBX26_RS20410	COG3706	GGDEF domain
DBX26_RS20440	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DBX26_RS20455	COG0579	oxidoreductase
DBX26_RS20465	COG3706	GGDEF domain
DBX26_RS20490	COG0189	ligase activity
DBX26_RS20495	COG4067	protein conserved in archaea
DBX26_RS20495	COG0189	ligase activity
DBX26_RS20505	COG1166	arginine decarboxylase activity
DBX26_RS20510	COG0010	Belongs to the arginase family
DBX26_RS20515	COG2814	Major facilitator Superfamily
DBX26_RS20520	COG1770	oligopeptidase
DBX26_RS20540	COG0848	biopolymer transport protein
DBX26_RS20545	COG0811	peptide transport
DBX26_RS20550	COG0811	peptide transport
DBX26_RS20570	COG0745	RESPONSE REGULATOR receiver
DBX26_RS20575	COG0039	L-malate dehydrogenase activity
DBX26_RS20580	COG0584	glycerophosphoryl diester phosphodiesterase
DBX26_RS20590	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DBX26_RS20660	COG1901	pseudouridine methyltransferase
DBX26_RS20665	COG0312	modulator of DNA gyrase
DBX26_RS20670	COG0312	modulator of DNA gyrase
DBX26_RS20675	COG0351	phosphomethylpyrimidine kinase
DBX26_RS20680	COG1116	anion transmembrane transporter activity
DBX26_RS20685	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DBX26_RS20690	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DBX26_RS20695	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
DBX26_RS20715	COG0243	molybdopterin cofactor binding
DBX26_RS20720	COG3005	denitrification pathway
DBX26_RS20735	COG1929	Belongs to the glycerate kinase type-1 family
DBX26_RS20745	COG3835	regulator
DBX26_RS20780	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
DBX26_RS20795	COG3047	cAMP biosynthetic process
DBX26_RS20820	COG2375	cellular response to nickel ion
DBX26_RS20825	COG0800	Aldolase
DBX26_RS20830	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DBX26_RS20845	COG1028	Short-chain dehydrogenase reductase Sdr
DBX26_RS20850	COG1414	Transcriptional regulator
DBX26_RS20855	COG0583	DNA-binding transcription factor activity
DBX26_RS20870	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
DBX26_RS20885	COG2199	diguanylate cyclase activity
DBX26_RS20890	COG0561	phosphatase activity
DBX26_RS20895	COG0583	DNA-binding transcription factor activity
DBX26_RS20905	COG0564	pseudouridine synthase activity
DBX26_RS20910	COG0534	Mate efflux family protein
DBX26_RS20915	COG5001	Diguanylate cyclase
DBX26_RS20930	COG3123	guanosine phosphorylase activity
DBX26_RS20970	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DBX26_RS20975	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DBX26_RS20980	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
DBX26_RS20990	COG2259	Doxx family
DBX26_RS20995	COG1741	Belongs to the pirin family
DBX26_RS21015	COG0363	glucosamine-6-phosphate deaminase activity
DBX26_RS21030	COG1131	(ABC) transporter
DBX26_RS21040	COG0786	glutamate:sodium symporter activity
DBX26_RS21050	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DBX26_RS21055	COG3279	Response regulator of the LytR AlgR family
DBX26_RS21060	COG3275	phosphorelay sensor kinase activity
DBX26_RS21075	COG4591	ABC-type transport system involved in lipoprotein release permease component
DBX26_RS21080	COG1136	(ABC) transporter
DBX26_RS21105	COG0444	Belongs to the ABC transporter superfamily
DBX26_RS21110	COG4608	Belongs to the ABC transporter superfamily
DBX26_RS21135	COG1444	tRNA N-acetyltransferase activity
DBX26_RS21190	COG0259	pyridoxamine-phosphate oxidase activity
DBX26_RS21220	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DBX26_RS21245	COG3119	arylsulfatase activity
DBX26_RS21250	COG3634	alkyl hydroperoxide reductase activity
DBX26_RS21260	COG1846	Transcriptional regulator
DBX26_RS21265	COG1764	response to oxidative stress
DBX26_RS21280	COG0577	efflux transmembrane transporter activity
DBX26_RS21285	COG1136	(ABC) transporter
DBX26_RS21290	COG4221	oxidoreductase activity
DBX26_RS21300	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DBX26_RS21305	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DBX26_RS21310	COG4521	taurine ABC transporter
DBX26_RS21315	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
DBX26_RS21320	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DBX26_RS21330	COG2211	Major facilitator Superfamily
DBX26_RS21335	COG3940	Belongs to the glycosyl hydrolase 43 family
DBX26_RS21340	COG2017	converts alpha-aldose to the beta-anomer
DBX26_RS21350	COG2160	L-arabinose isomerase activity
DBX26_RS21360	COG1069	ribulokinase activity
DBX26_RS21365	COG1879	ABC-type sugar transport system periplasmic component
DBX26_RS21370	COG1129	ABC transporter
DBX26_RS21375	COG1172	Belongs to the binding-protein-dependent transport system permease family
DBX26_RS21385	COG4772	TonB-dependent receptor
DBX26_RS21390	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
DBX26_RS21395	COG3119	arylsulfatase activity
DBX26_RS21400	COG3119	arylsulfatase activity
DBX26_RS21405	COG0641	radical SAM
DBX26_RS21415	COG0747	negative chemotaxis
DBX26_RS21425	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DBX26_RS21440	COG1940	carbohydrate kinase activity
DBX26_RS21450	COG0659	secondary active sulfate transmembrane transporter activity
DBX26_RS21455	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DBX26_RS21460	COG1085	galactose-1-phosphate uridylyltransferase
DBX26_RS21470	COG5426	von Willebrand factor, type A
DBX26_RS21475	COG5492	domain, Protein
DBX26_RS21480	COG0612	Peptidase, M16
DBX26_RS21500	COG1621	beta-fructofuranosidase activity
DBX26_RS21530	COG2207	Transcriptional regulator
DBX26_RS21535	COG2423	ornithine cyclodeaminase activity
DBX26_RS21540	COG0251	oxidation-reduction process
DBX26_RS21545	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DBX26_RS21565	COG0662	Cupin 2, conserved barrel domain protein
DBX26_RS21570	COG0583	DNA-binding transcription factor activity
DBX26_RS21600	COG0583	DNA-binding transcription factor activity
DBX26_RS21620	COG3171	Protein conserved in bacteria
DBX26_RS21635	COG0814	amino acid
DBX26_RS21665	COG4604	ABC transporter, ATP-binding protein
DBX26_RS21670	COG4605	iron ion homeostasis
DBX26_RS21675	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DBX26_RS21680	COG4607	ABC-type enterochelin transport system periplasmic component
DBX26_RS21685	COG0583	DNA-binding transcription factor activity
DBX26_RS21690	COG4771	TonB-dependent receptor
DBX26_RS21695	COG2814	Major facilitator Superfamily
DBX26_RS21705	COG1263	PTS System
DBX26_RS21705	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DBX26_RS21735	COG0366	Alpha amylase catalytic
DBX26_RS21750	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
DBX26_RS21755	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
DBX26_RS21760	COG1162	GTPase activity
DBX26_RS21765	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DBX26_RS21765	COG1263	PTS System
DBX26_RS21770	COG1999	signal sequence binding
DBX26_RS21785	COG2909	trisaccharide binding
DBX26_RS21790	COG0058	SHG alpha-glucan phosphorylase activity
DBX26_RS21795	COG1640	4-alpha-glucanotransferase
DBX26_RS21800	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DBX26_RS21805	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DBX26_RS21810	COG0366	Alpha amylase catalytic
DBX26_RS21815	COG3339	Conserved Protein
DBX26_RS21820	COG1301	dicarboxylic acid transport
DBX26_RS21835	COG2095	MarC family integral membrane protein
DBX26_RS21840	COG4667	esterase of the alpha-beta hydrolase superfamily
DBX26_RS21845	COG1054	Belongs to the UPF0176 family
DBX26_RS21860	COG1686	Belongs to the peptidase S11 family
DBX26_RS21865	COG4628	conserved protein (DUF2132)
DBX26_RS21875	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DBX26_RS21880	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
DBX26_RS21885	COG0628	permease
DBX26_RS21895	COG1566	PFAM secretion protein HlyD family protein
DBX26_RS21935	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
DBX26_RS21950	COG0346	lactoylglutathione lyase activity
DBX26_RS21970	COG0745	RESPONSE REGULATOR receiver
DBX26_RS21995	COG3300	MHYT domain
DBX26_RS21995	COG5001	Diguanylate cyclase
DBX26_RS22000	COG0156	8-amino-7-oxononanoate synthase activity
DBX26_RS22005	COG1063	alcohol dehydrogenase
DBX26_RS22015	COG1278	Cold shock
DBX26_RS22030	COG0668	transmembrane transport
DBX26_RS22040	COG1304	FMN binding
DBX26_RS22045	COG1620	l-lactate permease
DBX26_RS22050	COG0583	DNA-binding transcription factor activity
DBX26_RS22055	COG1505	serine-type exopeptidase activity
DBX26_RS22065	COG1067	ATP-dependent peptidase activity
DBX26_RS22085	COG1247	-acetyltransferase
DBX26_RS22090	COG0437	4 iron, 4 sulfur cluster binding
DBX26_RS22095	COG0348	domain, Protein
DBX26_RS22105	COG4720	Psort location CytoplasmicMembrane, score
DBX26_RS22110	COG1566	PFAM secretion protein HlyD family protein
DBX26_RS22120	COG3706	GGDEF domain
DBX26_RS22135	COG0813	purine-nucleoside phosphorylase activity
DBX26_RS22145	COG3272	Protein of unknown function (DUF1722)
DBX26_RS22150	COG0789	Transcriptional regulator
DBX26_RS22155	COG0415	Belongs to the DNA photolyase family
DBX26_RS22160	COG1388	LysM domain
DBX26_RS22160	COG1376	ErfK ybiS ycfS ynhG family protein
DBX26_RS22170	COG0513	Belongs to the DEAD box helicase family
DBX26_RS22175	COG0840	transmembrane signaling receptor activity
DBX26_RS22185	COG0573	inorganic phosphate transmembrane transporter activity
DBX26_RS22190	COG0581	inorganic phosphate transmembrane transporter activity
DBX26_RS22195	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DBX26_RS22205	COG2304	oxidoreductase activity
DBX26_RS22225	COG0714	Associated with various cellular activities
DBX26_RS22255	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DBX26_RS22270	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
DBX26_RS22275	COG1120	ATPase activity
DBX26_RS22280	COG4774	siderophore transport
DBX26_RS22285	COG1132	(ABC) transporter
DBX26_RS22290	COG0583	DNA-binding transcription factor activity
DBX26_RS22305	COG1012	belongs to the aldehyde dehydrogenase family
DBX26_RS22315	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DBX26_RS22325	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
DBX26_RS22330	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DBX26_RS22335	COG2084	Dehydrogenase
DBX26_RS22350	COG2130	NADP-dependent
DBX26_RS22355	COG1309	transcriptional regulator
DBX26_RS22360	COG3097	Belongs to the UPF0267 family
DBX26_RS22390	COG0438	transferase activity, transferring glycosyl groups
DBX26_RS22400	COG0489	protein tyrosine kinase activity
DBX26_RS22400	COG3206	protein involved in exopolysaccharide biosynthesis
DBX26_RS22415	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DBX26_RS22420	COG3842	ATPase activity
DBX26_RS22430	COG1175	transmembrane transport
DBX26_RS22435	COG3833	ABC-type maltose transport systems, permease component
DBX26_RS22450	COG3437	response regulator, receiver
DBX26_RS22450	COG4999	Histidine kinase
DBX26_RS22450	COG2205	protein histidine kinase activity
DBX26_RS22450	COG3850	Histidine kinase
DBX26_RS22455	COG3437	response regulator, receiver
DBX26_RS22460	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DBX26_RS22495	COG0741	lytic transglycosylase activity
DBX26_RS22505	COG1522	sequence-specific DNA binding
DBX26_RS22515	COG1448	Aminotransferase
DBX26_RS22540	COG0071	Belongs to the small heat shock protein (HSP20) family
DBX26_RS22545	COG2199	diguanylate cyclase activity
DBX26_RS22585	COG1061	Type III restriction enzyme res subunit
DBX26_RS22610	COG0583	DNA-binding transcription factor activity
DBX26_RS22620	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
DBX26_RS22625	COG1501	Belongs to the glycosyl hydrolase 31 family
DBX26_RS22650	COG1882	Formate acetyltransferase
DBX26_RS22655	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DBX26_RS22665	COG1349	DNA-binding transcription factor activity
DBX26_RS22670	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DBX26_RS22675	COG2084	Dehydrogenase
DBX26_RS22805	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DBX26_RS22810	COG1085	galactose-1-phosphate uridylyltransferase
DBX26_RS22820	COG2017	converts alpha-aldose to the beta-anomer
DBX26_RS22825	COG1609	Transcriptional regulator
DBX26_RS22830	COG1609	Transcriptional regulator
DBX26_RS22835	COG3250	beta-galactosidase activity
DBX26_RS22845	COG4580	involved in the transport of maltose and maltodextrins
DBX26_RS22855	COG2211	Major facilitator Superfamily
DBX26_RS22885	COG4974	Belongs to the 'phage' integrase family
DBX26_RS22910	COG1609	Transcriptional regulator
DBX26_RS22915	COG1172	Belongs to the binding-protein-dependent transport system permease family
DBX26_RS22920	COG1129	ABC transporter
DBX26_RS22925	COG1879	ABC-type sugar transport system periplasmic component
DBX26_RS22940	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DBX26_RS22955	COG1252	NADH dehydrogenase
DBX26_RS22985	COG2217	Heavy metal translocating P-type atpase
DBX26_RS23005	COG5002	protein histidine kinase activity
DBX26_RS23035	COG1132	(ABC) transporter
DBX26_RS23055	COG2176	DNA-directed DNA polymerase activity
DBX26_RS23065	COG2354	Protein conserved in bacteria
DBX26_RS23070	COG0418	dihydroorotase activity
DBX26_RS23085	COG3217	Mosc domain protein beta barrel domain protein
DBX26_RS23085	COG0633	Ferredoxin
DBX26_RS23085	COG3217	Mosc domain protein beta barrel domain protein
DBX26_RS23085	COG0633	Ferredoxin
DBX26_RS23090	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DBX26_RS23095	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DBX26_RS23130	COG0748	coenzyme F420 binding
DBX26_RS23135	COG0784	Response regulator, receiver
DBX26_RS23135	COG0835	chemotaxis
DBX26_RS23140	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DBX26_RS23160	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DBX26_RS23175	COG1063	alcohol dehydrogenase
DBX26_RS23180	COG0583	DNA-binding transcription factor activity
DBX26_RS23185	COG1902	pentaerythritol trinitrate reductase activity
DBX26_RS23200	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DBX26_RS23205	COG4948	Mandelate Racemase Muconate Lactonizing
DBX26_RS23215	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DBX26_RS23240	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
DBX26_RS23250	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
DBX26_RS23260	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DBX26_RS23275	COG1979	alcohol dehydrogenase
DBX26_RS23280	COG0366	Alpha amylase catalytic
DBX26_RS23290	COG1472	Belongs to the glycosyl hydrolase 3 family
DBX26_RS23305	COG2249	NAD(P)H dehydrogenase (quinone) activity
DBX26_RS23310	COG0589	response to stress
DBX26_RS23315	COG2067	long-chain fatty acid transport protein
DBX26_RS23320	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DBX26_RS23340	COG2871	sodium ion transport
DBX26_RS23350	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DBX26_RS23370	COG3383	formate dehydrogenase (NAD+) activity
DBX26_RS23380	COG0842	Transport permease protein
DBX26_RS23385	COG1131	(ABC) transporter
DBX26_RS23400	COG0798	PFAM Bile acid sodium symporter
DBX26_RS23410	COG0747	negative chemotaxis
DBX26_RS23430	COG0814	amino acid
DBX26_RS23445	COG3314	Sporulation integral membrane protein YlbJ
DBX26_RS23470	COG0739	heme binding
DBX26_RS23475	COG5001	Diguanylate cyclase
DBX26_RS23480	COG0583	DNA-binding transcription factor activity
DBX26_RS23505	COG0179	Fumarylacetoacetate (FAA) hydrolase
DBX26_RS23525	COG1280	lysine exporter protein (LysE YggA)
DBX26_RS23530	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DBX26_RS23545	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
DBX26_RS23550	COG1845	cytochrome c oxidase, subunit III
DBX26_RS23570	COG1612	heme a metabolic process
DBX26_RS23575	COG0109	protoheme IX farnesyltransferase activity
DBX26_RS23580	COG0545	Peptidyl-prolyl cis-trans isomerase
DBX26_RS23610	COG1278	Cold shock
DBX26_RS23635	COG0577	efflux transmembrane transporter activity
DBX26_RS23635	COG1136	(ABC) transporter
DBX26_RS23645	COG0840	transmembrane signaling receptor activity
DBX26_RS23650	COG0783	Belongs to the Dps family
DBX26_RS23660	COG2133	pyrroloquinoline quinone binding
DBX26_RS23665	COG1454	alcohol dehydrogenase
DBX26_RS23670	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
DBX26_RS23690	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DBX26_RS23695	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DBX26_RS23700	COG3186	Phenylalanine-4-hydroxylase
DBX26_RS23725	COG3530	Putative quorum-sensing-regulated virulence factor
DBX26_RS23730	COG0133	tryptophan synthase activity
DBX26_RS23740	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
DBX26_RS23745	COG0523	cobalamin synthesis protein
DBX26_RS23750	COG0513	Belongs to the DEAD box helicase family
DBX26_RS23765	COG2200	EAL domain
DBX26_RS23770	COG1119	ATPase activity
DBX26_RS23790	COG1454	alcohol dehydrogenase
DBX26_RS23815	COG0446	pyridine nucleotide-disulphide oxidoreductase
DBX26_RS23815	COG1902	pentaerythritol trinitrate reductase activity
DBX26_RS23820	COG0247	lactate metabolic process
DBX26_RS23820	COG2181	nitrate reductase activity
DBX26_RS23825	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
DBX26_RS23835	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DBX26_RS23845	COG0656	L-ascorbic acid biosynthetic process
DBX26_RS23850	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DBX26_RS23865	COG0356	it plays a direct role in the translocation of protons across the membrane
DBX26_RS23875	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DBX26_RS23875	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DBX26_RS23880	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DBX26_RS23910	COG0789	Transcriptional regulator
DBX26_RS23915	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DBX26_RS23940	COG1012	belongs to the aldehyde dehydrogenase family
DBX26_RS23945	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
DBX26_RS23965	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DBX26_RS23975	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DBX26_RS23980	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DBX26_RS23995	COG0446	pyridine nucleotide-disulphide oxidoreductase
DBX26_RS23995	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DBX26_RS24010	COG1760	l-serine dehydratase
DBX26_RS24020	COG1064	alcohol dehydrogenase
DBX26_RS24025	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DBX26_RS24040	COG2207	Transcriptional regulator
DBX26_RS24090	COG1070	Carbohydrate kinase
DBX26_RS24100	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DBX26_RS24120	COG2855	membrane
DBX26_RS24135	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DBX26_RS24140	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
DBX26_RS24145	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
DBX26_RS24150	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
DBX26_RS24150	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
DBX26_RS24160	COG1414	Transcriptional regulator
DBX26_RS24170	COG0730	response to heat
DBX26_RS24200	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
DBX26_RS24205	COG0589	response to stress
DBX26_RS24215	COG2111	Na H antiporter
DBX26_RS24215	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DBX26_RS24220	COG1006	Multisubunit Na H antiporter MnhC subunit
DBX26_RS24225	COG0651	ATP synthesis coupled electron transport
DBX26_RS24230	COG1863	multisubunit Na H antiporter MnhE subunit
DBX26_RS24235	COG2212	antiporter activity
DBX26_RS24240	COG1320	monovalent cation:proton antiporter activity
DBX26_RS24245	COG1349	DNA-binding transcription factor activity
DBX26_RS24250	COG2407	Converts the aldose L-fucose into the corresponding ketose L-fuculose
DBX26_RS24255	COG1070	Carbohydrate kinase
DBX26_RS24260	COG0235	Class ii aldolase
DBX26_RS24265	COG1454	alcohol dehydrogenase
DBX26_RS24270	COG0513	Belongs to the DEAD box helicase family
DBX26_RS24280	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DBX26_RS24315	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DBX26_RS24320	COG0569	domain protein
DBX26_RS24325	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DBX26_RS24330	COG0745	RESPONSE REGULATOR receiver
DBX26_RS24335	COG2205	protein histidine kinase activity
DBX26_RS24350	COG0668	transmembrane transport
DBX26_RS24375	COG3300	MHYT domain
DBX26_RS24375	COG5001	Diguanylate cyclase
DBX26_RS24405	COG3290	protein histidine kinase activity
DBX26_RS24405	COG0840	transmembrane signaling receptor activity
DBX26_RS24415	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
DBX26_RS24420	COG2197	response regulator
DBX26_RS24425	COG3850	Histidine kinase
DBX26_RS24430	COG2223	nitrite transmembrane transporter activity
DBX26_RS24435	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
DBX26_RS24440	COG1140	nitrate reductase beta subunit
DBX26_RS24445	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
DBX26_RS24450	COG2181	nitrate reductase activity
DBX26_RS24490	COG0583	DNA-binding transcription factor activity
DBX26_RS24495	COG1063	alcohol dehydrogenase
DBX26_RS24510	COG3706	GGDEF domain
DBX26_RS24605	COG0840	transmembrane signaling receptor activity
DBX26_RS24630	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DBX26_RS24680	COG1484	DNA-dependent DNA replication
DBX26_RS24690	COG0464	growth
DBX26_RS24765	COG0714	Associated with various cellular activities
DBX26_RS24920	COG0330	HflC and HflK could
DBX26_RS24945	COG1278	Cold shock
DBX26_RS25155	COG5002	protein histidine kinase activity
DBX26_RS25225	COG0789	Transcriptional regulator
DBX26_RS25230	COG2217	Heavy metal translocating P-type atpase
DBX26_RS25260	COG0745	RESPONSE REGULATOR receiver
DBX26_RS25265	COG5002	protein histidine kinase activity
DBX26_RS25270	COG4580	involved in the transport of maltose and maltodextrins
DBX26_RS25285	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family