locus-tag	class	description
H9L11_RS00015	COG0457	Tetratricopeptide repeat
H9L11_RS00085	COG4790	Type iii secretion
H9L11_RS00090	COG4794	Type iii secretion
H9L11_RS00095	COG4791	protein targeting
H9L11_RS00100	COG4792	protein secretion
H9L11_RS00105	COG2207	Transcriptional regulator
H9L11_RS00135	COG3177	Filamentation induced by cAMP protein fic
H9L11_RS00155	COG4669	(LipO)protein
H9L11_RS00225	COG1012	belongs to the aldehyde dehydrogenase family
H9L11_RS00230	COG3284	Transcriptional regulator
H9L11_RS00250	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
H9L11_RS00255	COG0363	glucosamine-6-phosphate deaminase activity
H9L11_RS00260	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
H9L11_RS00265	COG2207	Transcriptional regulator
H9L11_RS00275	COG4565	transcriptional regulatory protein
H9L11_RS00280	COG3290	protein histidine kinase activity
H9L11_RS00295	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H9L11_RS00325	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
H9L11_RS00345	COG1279	arginine transmembrane transporter activity
H9L11_RS00355	COG0583	DNA-binding transcription factor activity
H9L11_RS00360	COG4771	TonB-dependent receptor
H9L11_RS00375	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H9L11_RS00435	COG0582	viral genome integration into host DNA
H9L11_RS00605	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H9L11_RS00615	COG3768	UPF0283 membrane protein
H9L11_RS00620	COG3106	COG3106 Predicted ATPase
H9L11_RS00640	COG0784	Response regulator, receiver
H9L11_RS00640	COG2205	protein histidine kinase activity
H9L11_RS00650	COG0494	nUDIX hydrolase
H9L11_RS00655	COG0814	amino acid
H9L11_RS00660	COG1760	l-serine dehydratase
H9L11_RS00665	COG2200	EAL domain
H9L11_RS00675	COG0720	synthase
H9L11_RS00680	COG0840	transmembrane signaling receptor activity
H9L11_RS00685	COG0017	Asparaginyl-tRNA synthetase
H9L11_RS00695	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H9L11_RS00710	COG1448	Aminotransferase
H9L11_RS00730	COG0840	transmembrane signaling receptor activity
H9L11_RS00735	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H9L11_RS00765	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
H9L11_RS00780	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H9L11_RS00785	COG3108	Peptidase M15
H9L11_RS00790	COG2989	Protein conserved in bacteria
H9L11_RS00815	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
H9L11_RS00825	COG4235	cytochrome complex assembly
H9L11_RS00825	COG3088	subunit of a heme lyase
H9L11_RS00835	COG1138	Cytochrome C-type biogenesis protein
H9L11_RS00840	COG3301	Polysulphide reductase, NrfD
H9L11_RS00845	COG0437	4 iron, 4 sulfur cluster binding
H9L11_RS00855	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
H9L11_RS00875	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
H9L11_RS00880	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H9L11_RS00910	COG0019	diaminopimelate decarboxylase activity
H9L11_RS00950	COG0322	excinuclease ABC activity
H9L11_RS00955	COG2197	response regulator
H9L11_RS00960	COG0417	DNA replication proofreading
H9L11_RS00980	COG1187	pseudouridine synthase activity
H9L11_RS00990	COG0009	L-threonylcarbamoyladenylate synthase
H9L11_RS00995	COG0613	PHP domain protein
H9L11_RS01005	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
H9L11_RS01010	COG0512	Glutamine amidotransferase of anthranilate synthase
H9L11_RS01020	COG0134	indole-3-glycerol-phosphate synthase activity
H9L11_RS01020	COG0135	phosphoribosylanthranilate isomerase activity
H9L11_RS01030	COG0159	tryptophan synthase activity
H9L11_RS01035	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H9L11_RS01040	COG0318	PFAM AMP-dependent synthetase and ligase
H9L11_RS01045	COG1301	dicarboxylic acid transport
H9L11_RS01065	COG2917	probably involved in intracellular septation
H9L11_RS01075	COG2350	Protein conserved in bacteria
H9L11_RS01085	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
H9L11_RS01090	COG0583	DNA-binding transcription factor activity
H9L11_RS01105	COG5001	Diguanylate cyclase
H9L11_RS01110	COG1032	radical SAM domain protein
H9L11_RS01140	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
H9L11_RS01145	COG0463	Glycosyl transferase, family 2
H9L11_RS01150	COG0745	RESPONSE REGULATOR receiver
H9L11_RS01155	COG5002	protein histidine kinase activity
H9L11_RS01155	COG3850	Histidine kinase
H9L11_RS01190	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
H9L11_RS01210	COG1136	(ABC) transporter
H9L11_RS01210	COG0577	efflux transmembrane transporter activity
H9L11_RS01215	COG1136	(ABC) transporter
H9L11_RS01215	COG0577	efflux transmembrane transporter activity
H9L11_RS01220	COG0577	efflux transmembrane transporter activity
H9L11_RS01220	COG1136	(ABC) transporter
H9L11_RS01230	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H9L11_RS01255	COG3118	belongs to the thioredoxin family
H9L11_RS01260	COG4232	protein-disulfide reductase activity
H9L11_RS01295	COG2863	cytochrome
H9L11_RS01300	COG3258	Cytochrome c
H9L11_RS01305	COG2995	paraquat-inducible protein a
H9L11_RS01310	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
H9L11_RS01310	COG3008	intermembrane lipid transfer
H9L11_RS01330	COG4166	transmembrane transport
H9L11_RS01340	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
H9L11_RS01345	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
H9L11_RS01355	COG0539	negative regulation of cytoplasmic translation
H9L11_RS01360	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
H9L11_RS01365	COG0616	signal peptide processing
H9L11_RS01370	COG1028	Short-chain dehydrogenase reductase Sdr
H9L11_RS01385	COG0587	DNA-directed DNA polymerase activity
H9L11_RS01390	COG0835	chemotaxis
H9L11_RS01390	COG0784	Response regulator, receiver
H9L11_RS01395	COG1940	carbohydrate kinase activity
H9L11_RS01400	COG0469	pyruvate kinase activity
H9L11_RS01405	COG4667	esterase of the alpha-beta hydrolase superfamily
H9L11_RS01420	COG0733	neurotransmitter:sodium symporter activity
H9L11_RS01435	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9L11_RS01435	COG1263	PTS System
H9L11_RS01440	COG0084	hydrolase, TatD family'
H9L11_RS01445	COG0470	DNA polymerase III
H9L11_RS01450	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
H9L11_RS01455	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
H9L11_RS01485	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
H9L11_RS01490	COG0416	fatty acid biosynthetic process
H9L11_RS01500	COG1399	metal-binding, possibly nucleic acid-binding protein
H9L11_RS01505	COG0424	maF-like protein
H9L11_RS01510	COG0564	pseudouridine synthase activity
H9L11_RS01515	COG1530	ribonuclease E activity
H9L11_RS01520	COG0659	secondary active sulfate transmembrane transporter activity
H9L11_RS01530	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
H9L11_RS01535	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
H9L11_RS01545	COG0572	uridine kinase
H9L11_RS01555	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H9L11_RS01555	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H9L11_RS01575	COG2186	Transcriptional regulator
H9L11_RS01580	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
H9L11_RS01585	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
H9L11_RS01590	COG0653	protein targeting
H9L11_RS01595	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H9L11_RS01600	COG3706	GGDEF domain
H9L11_RS01605	COG0366	Alpha amylase catalytic
H9L11_RS01610	COG1122	ATPase activity
H9L11_RS01615	COG4120	Belongs to the binding-protein-dependent transport system permease family
H9L11_RS01625	COG3092	negative regulation of chromosome organization
H9L11_RS01630	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
H9L11_RS01635	COG0857	belongs to the CobB CobQ family
H9L11_RS01635	COG0280	phosphate acetyltransferase
H9L11_RS01645	COG0435	Glutathione S-transferase
H9L11_RS01655	COG0444	Belongs to the ABC transporter superfamily
H9L11_RS01660	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H9L11_RS01665	COG0601	transmembrane transport
H9L11_RS01675	COG0314	molybdopterin synthase activity
H9L11_RS01680	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
H9L11_RS01685	COG0315	cyclic pyranopterin monophosphate synthase activity
H9L11_RS01690	COG0521	Mo-molybdopterin cofactor biosynthetic process
H9L11_RS01695	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
H9L11_RS01700	COG0391	Required for morphogenesis under gluconeogenic growth conditions
H9L11_RS01705	COG2198	Histidine kinase
H9L11_RS01710	COG2204	response regulator
H9L11_RS01715	COG0556	nucleotide-excision repair
H9L11_RS01725	COG1882	Formate acetyltransferase
H9L11_RS01730	COG4657	Part of a membrane complex involved in electron transport
H9L11_RS01735	COG2878	Part of a membrane complex involved in electron transport
H9L11_RS01740	COG4656	Part of a membrane complex involved in electron transport
H9L11_RS01745	COG4658	electron transport chain
H9L11_RS01750	COG4659	FMN binding
H9L11_RS01755	COG4660	Part of a membrane complex involved in electron transport
H9L11_RS01760	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
H9L11_RS01765	COG0346	lactoylglutathione lyase activity
H9L11_RS01775	COG2885	chlorophyll binding
H9L11_RS01785	COG2056	Na+-H+ antiporter family
H9L11_RS01805	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
H9L11_RS01825	COG1454	alcohol dehydrogenase
H9L11_RS01825	COG1012	belongs to the aldehyde dehydrogenase family
H9L11_RS01830	COG2095	MarC family integral membrane protein
H9L11_RS01835	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H9L11_RS01840	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
H9L11_RS01845	COG1757	Na H antiporter
H9L11_RS01860	COG3081	Nucleoid-associated protein
H9L11_RS01865	COG3082	Protein of unknown function (DUF1414)
H9L11_RS01880	COG0123	including yeast histone deacetylase and acetoin utilization protein
H9L11_RS01895	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
H9L11_RS01900	COG0778	Nitroreductase
H9L11_RS01910	COG1902	pentaerythritol trinitrate reductase activity
H9L11_RS01910	COG0446	pyridine nucleotide-disulphide oxidoreductase
H9L11_RS01915	COG0616	signal peptide processing
H9L11_RS01920	COG0252	asparaginase activity
H9L11_RS01925	COG3139	Protein of unknown function (DUF1315)
H9L11_RS01935	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
H9L11_RS01940	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
H9L11_RS01955	COG2226	methyltransferase
H9L11_RS01970	COG1785	Belongs to the alkaline phosphatase family
H9L11_RS01980	COG0346	lactoylglutathione lyase activity
H9L11_RS01985	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
H9L11_RS01990	COG0668	transmembrane transport
H9L11_RS01995	COG2983	Belongs to the UPF0260 family
H9L11_RS02000	COG2261	transglycosylase associated protein
H9L11_RS02010	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
H9L11_RS02015	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
H9L11_RS02030	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
H9L11_RS02035	COG2832	Protein of unknown function (DUF454)
H9L11_RS02040	COG0745	RESPONSE REGULATOR receiver
H9L11_RS02045	COG0583	DNA-binding transcription factor activity
H9L11_RS02050	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
H9L11_RS02055	COG1286	toxin biosynthetic process
H9L11_RS02060	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
H9L11_RS02065	COG0285	dihydrofolate synthase activity
H9L11_RS02070	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
H9L11_RS02075	COG0101	tRNA pseudouridine synthase activity
H9L11_RS02085	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
H9L11_RS02090	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H9L11_RS02095	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
H9L11_RS02100	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
H9L11_RS02100	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H9L11_RS02105	COG0431	NADPH-dependent FMN reductase
H9L11_RS02115	COG3101	peptidyl-lysine hydroxylation
H9L11_RS02120	COG2860	membrane
H9L11_RS02125	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
H9L11_RS02130	COG2890	protein-(glutamine-N5) methyltransferase activity
H9L11_RS02135	COG2840	Smr protein MutS2
H9L11_RS02140	COG2062	phosphohistidine phosphatase, SixA
H9L11_RS02155	COG1250	3-hydroxyacyl-CoA dehydrogenase
H9L11_RS02155	COG1024	Enoyl-CoA hydratase
H9L11_RS02160	COG0183	Belongs to the thiolase family
H9L11_RS02180	COG2067	long-chain fatty acid transport protein
H9L11_RS02195	COG4235	cytochrome complex assembly
H9L11_RS02195	COG3088	subunit of a heme lyase
H9L11_RS02205	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H9L11_RS02210	COG1138	Cytochrome C-type biogenesis protein
H9L11_RS02215	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
H9L11_RS02220	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
H9L11_RS02225	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
H9L11_RS02230	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
H9L11_RS02235	COG4133	protoheme IX ABC transporter activity
H9L11_RS02245	COG0835	chemotaxis
H9L11_RS02255	COG1192	Involved in chromosome partitioning
H9L11_RS02260	COG2201	protein-glutamate methylesterase activity
H9L11_RS02265	COG2198	Histidine kinase
H9L11_RS02265	COG0784	Response regulator, receiver
H9L11_RS02265	COG0643	Histidine kinase
H9L11_RS02270	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
H9L11_RS02305	COG1684	flagellar biosynthetic protein fliR
H9L11_RS02310	COG1987	bacterial-type flagellum assembly
H9L11_RS02365	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
H9L11_RS02375	COG1677	Flagellar hook-basal body complex protein FliE
H9L11_RS02395	COG1516	flagellar protein fliS
H9L11_RS02405	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
H9L11_RS02410	COG1334	flagellar protein FlaG
H9L11_RS02415	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
H9L11_RS02420	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
H9L11_RS02425	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
H9L11_RS02430	COG2837	iron assimilation
H9L11_RS02455	COG1393	Belongs to the ArsC family
H9L11_RS02460	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H9L11_RS02475	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
H9L11_RS02480	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H9L11_RS02490	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
H9L11_RS02505	COG4783	chaperone-mediated protein folding
H9L11_RS02510	COG1393	Belongs to the ArsC family
H9L11_RS02530	COG2233	PERMEase
H9L11_RS02540	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
H9L11_RS02545	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
H9L11_RS02550	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
H9L11_RS02560	COG0121	glutamine amidotransferase
H9L11_RS02565	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
H9L11_RS02570	COG1960	acyl-CoA dehydrogenase activity
H9L11_RS02605	COG0328	RNA-DNA hybrid ribonuclease activity
H9L11_RS02610	COG2226	methyltransferase
H9L11_RS02615	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H9L11_RS02620	COG0741	lytic transglycosylase activity
H9L11_RS02620	COG1388	LysM domain
H9L11_RS02630	COG3021	interspecies interaction between organisms
H9L11_RS02635	COG0347	Belongs to the P(II) protein family
H9L11_RS02650	COG0825	malonyl-CoA metabolic process
H9L11_RS02655	COG0587	DNA-directed DNA polymerase activity
H9L11_RS02665	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H9L11_RS02670	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H9L11_RS02680	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H9L11_RS02685	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
H9L11_RS02695	COG0750	zinc metalloprotease
H9L11_RS02700	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
H9L11_RS02705	COG0575	Belongs to the CDS family
H9L11_RS02710	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
H9L11_RS02715	COG0233	cytoplasmic translational termination
H9L11_RS02720	COG0528	UMP kinase activity
H9L11_RS02725	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
H9L11_RS02730	COG0052	Belongs to the universal ribosomal protein uS2 family
H9L11_RS02735	COG0024	Methionine aminopeptidase
H9L11_RS02740	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
H9L11_RS02750	COG0564	pseudouridine synthase activity
H9L11_RS02785	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
H9L11_RS02790	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H9L11_RS02815	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
H9L11_RS02825	COG0254	rRNA binding
H9L11_RS02830	COG1720	tRNA m6t6A37 methyltransferase activity
H9L11_RS02835	COG0442	prolyl-tRNA aminoacylation
H9L11_RS02855	COG0733	neurotransmitter:sodium symporter activity
H9L11_RS02875	COG0514	ATP-dependent DNA helicase (RecQ)
H9L11_RS02880	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
H9L11_RS02900	COG1477	protein flavinylation
H9L11_RS02905	COG2871	sodium ion transport
H9L11_RS02910	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
H9L11_RS02915	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
H9L11_RS02920	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
H9L11_RS02925	COG1805	sodium ion transport
H9L11_RS02930	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
H9L11_RS02935	COG0271	Belongs to the BolA IbaG family
H9L11_RS02940	COG2813	Specifically methylates the guanine in position
H9L11_RS02945	COG3056	Lipoprotein
H9L11_RS02965	COG1595	DNA-templated transcription, initiation
H9L11_RS02980	COG3248	Nucleoside-binding outer membrane protein
H9L11_RS02985	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
H9L11_RS02990	COG0693	protein deglycase activity
H9L11_RS02995	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
H9L11_RS03000	COG3706	GGDEF domain
H9L11_RS03005	COG2166	iron-sulfur cluster assembly
H9L11_RS03010	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
H9L11_RS03015	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
H9L11_RS03025	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
H9L11_RS03025	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
H9L11_RS03050	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
H9L11_RS03055	COG1074	ATP-dependent DNA helicase activity
H9L11_RS03060	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
H9L11_RS03080	COG3141	response to X-ray
H9L11_RS03095	COG2171	N-acyltransferase activity
H9L11_RS03100	COG0584	glycerophosphoryl diester phosphodiesterase
H9L11_RS03105	COG2271	Major facilitator Superfamily
H9L11_RS03110	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
H9L11_RS03115	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
H9L11_RS03120	COG1349	DNA-binding transcription factor activity
H9L11_RS03125	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
H9L11_RS03130	COG0598	Magnesium transport protein CorA
H9L11_RS03150	COG1609	Transcriptional regulator
H9L11_RS03155	COG0583	DNA-binding transcription factor activity
H9L11_RS03195	COG1022	Amp-dependent synthetase and ligase
H9L11_RS03205	COG0583	DNA-binding transcription factor activity
H9L11_RS03210	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
H9L11_RS03215	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
H9L11_RS03225	COG0560	Phosphoserine phosphatase
H9L11_RS03235	COG0813	purine-nucleoside phosphorylase activity
H9L11_RS03240	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
H9L11_RS03245	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
H9L11_RS03250	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
H9L11_RS03255	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
H9L11_RS03260	COG0084	hydrolase, TatD family'
H9L11_RS03290	COG3153	acetyltransferase
H9L11_RS03295	COG3154	lipid carrier protein
H9L11_RS03305	COG0826	peptidase U32
H9L11_RS03310	COG0826	peptidase U32
H9L11_RS03315	COG0534	Mate efflux family protein
H9L11_RS03330	COG1185	polyribonucleotide nucleotidyltransferase activity
H9L11_RS03335	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
H9L11_RS03340	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
H9L11_RS03345	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
H9L11_RS03350	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
H9L11_RS03355	COG0195	Participates in both transcription termination and antitermination
H9L11_RS03360	COG0779	Required for maturation of 30S ribosomal subunits
H9L11_RS03375	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
H9L11_RS03380	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H9L11_RS03385	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
H9L11_RS03390	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H9L11_RS03395	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
H9L11_RS03400	COG1534	Rna-binding protein
H9L11_RS03405	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
H9L11_RS03410	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
H9L11_RS03415	COG2027	D-alanyl-D-alanine carboxypeptidase
H9L11_RS03425	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
H9L11_RS03430	COG0739	heme binding
H9L11_RS03455	COG0628	permease
H9L11_RS03465	COG0784	Response regulator, receiver
H9L11_RS03465	COG2205	protein histidine kinase activity
H9L11_RS03470	COG0747	negative chemotaxis
H9L11_RS03480	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H9L11_RS03485	COG0444	Belongs to the ABC transporter superfamily
H9L11_RS03490	COG4608	Belongs to the ABC transporter superfamily
H9L11_RS03500	COG2971	BadF BadG BcrA BcrD
H9L11_RS03515	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H9L11_RS03520	COG3842	ATPase activity
H9L11_RS03530	COG1840	ABC-type Fe3 transport system, periplasmic component
H9L11_RS03535	COG0004	ammonium transporteR
H9L11_RS03545	COG3112	Uncharacterised protein family (UPF0231)
H9L11_RS03550	COG1049	propionate catabolic process, 2-methylcitrate cycle
H9L11_RS03555	COG1752	Esterase of the alpha-beta hydrolase superfamily
H9L11_RS03560	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H9L11_RS03565	COG1643	Atp-dependent helicase
H9L11_RS03570	COG1489	DNA binding
H9L11_RS03580	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
H9L11_RS03590	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
H9L11_RS03595	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
H9L11_RS03600	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
H9L11_RS03605	COG1560	Kdo2-lipid A biosynthetic process
H9L11_RS03610	COG0842	Transport permease protein
H9L11_RS03615	COG1131	(ABC) transporter
H9L11_RS03620	COG0659	secondary active sulfate transmembrane transporter activity
H9L11_RS03625	COG0288	reversible hydration of carbon dioxide
H9L11_RS03640	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H9L11_RS03645	COG0508	dehydrogenase complex catalyzes the overall conversion of
H9L11_RS03650	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
H9L11_RS03655	COG2186	Transcriptional regulator
H9L11_RS03665	COG0157	Belongs to the NadC ModD family
H9L11_RS03670	COG4969	Belongs to the N-Me-Phe pilin family
H9L11_RS03675	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
H9L11_RS03680	COG1459	type II secretion system
H9L11_RS03690	COG0237	dephospho-CoA kinase activity
H9L11_RS03695	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
H9L11_RS03700	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
H9L11_RS03715	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
H9L11_RS03720	COG0228	four-way junction DNA binding
H9L11_RS03725	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
H9L11_RS03730	COG4137	Cytochrome C assembly protein
H9L11_RS03735	COG4536	flavin adenine dinucleotide binding
H9L11_RS03740	COG1854	S-ribosylhomocysteine lyase activity
H9L11_RS03755	COG0612	Peptidase, M16
H9L11_RS03760	COG1238	metal cluster binding
H9L11_RS03770	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
H9L11_RS03775	COG5016	pyruvate
H9L11_RS03775	COG0511	ligase activity, forming carbon-carbon bonds
H9L11_RS03780	COG3630	sodium ion export across plasma membrane
H9L11_RS03840	COG0527	aspartate kinase activity
H9L11_RS03845	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
H9L11_RS03850	COG2137	regulation of response to DNA damage stimulus
H9L11_RS03855	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
H9L11_RS03860	COG1546	Belongs to the CinA family
H9L11_RS03910	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
H9L11_RS03915	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
H9L11_RS03925	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
H9L11_RS03930	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
H9L11_RS03940	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
H9L11_RS03945	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
H9L11_RS03950	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
H9L11_RS03955	COG0148	phosphopyruvate hydratase activity
H9L11_RS03960	COG0504	CTP synthase activity
H9L11_RS03965	COG3956	TIGRFAM MazG family protein
H9L11_RS03970	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H9L11_RS03975	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
H9L11_RS03985	COG0736	holo-[acyl-carrier-protein] synthase activity
H9L11_RS03990	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
H9L11_RS03995	COG1381	Involved in DNA repair and RecF pathway recombination
H9L11_RS04000	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
H9L11_RS04010	COG0681	Belongs to the peptidase S26 family
H9L11_RS04015	COG0481	GTPase activity
H9L11_RS04020	COG3086	response to oxidative stress
H9L11_RS04035	COG1595	DNA-templated transcription, initiation
H9L11_RS04040	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
H9L11_RS04050	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
H9L11_RS04070	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H9L11_RS04075	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H9L11_RS04080	COG3079	Belongs to the UPF0149 family
H9L11_RS04085	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
H9L11_RS04095	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
H9L11_RS04100	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
H9L11_RS04105	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H9L11_RS04115	COG0583	DNA-binding transcription factor activity
H9L11_RS04130	COG0668	transmembrane transport
H9L11_RS04135	COG0191	fructose-bisphosphate aldolase activity
H9L11_RS04145	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
H9L11_RS04150	COG4771	TonB-dependent receptor
H9L11_RS04155	COG0583	DNA-binding transcription factor activity
H9L11_RS04160	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
H9L11_RS04165	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
H9L11_RS04175	COG3091	SprT-like family
H9L11_RS04180	COG2356	endonuclease I
H9L11_RS04185	COG1385	rRNA (uridine-N3-)-methyltransferase activity
H9L11_RS04190	COG0189	ligase activity
H9L11_RS04195	COG1678	Uncharacterized ACR, COG1678
H9L11_RS04200	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
H9L11_RS04215	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
H9L11_RS04220	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
H9L11_RS04225	COG0762	integral membrane protein
H9L11_RS04230	COG1872	DUF167
H9L11_RS04240	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
H9L11_RS04245	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H9L11_RS04250	COG2066	Belongs to the glutaminase family
H9L11_RS04260	COG0220	tRNA (guanine-N7-)-methyltransferase activity
H9L11_RS04270	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
H9L11_RS04315	COG0840	transmembrane signaling receptor activity
H9L11_RS04390	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
H9L11_RS04395	COG1609	Transcriptional regulator
H9L11_RS04400	COG3394	polysaccharide catabolic process
H9L11_RS04405	COG1486	melibiose metabolic process
H9L11_RS04410	COG1447	Phosphotransferase system cellobiose-specific component IIA
H9L11_RS04415	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H9L11_RS04420	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H9L11_RS04425	COG0726	polysaccharide deacetylase
H9L11_RS04435	COG1028	Short-chain dehydrogenase reductase Sdr
H9L11_RS04450	COG0795	lipopolysaccharide-transporting ATPase activity
H9L11_RS04455	COG0795	lipopolysaccharide-transporting ATPase activity
H9L11_RS04460	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
H9L11_RS04465	COG2927	DNA polymerase III (CHI subunit)
H9L11_RS04470	COG0525	valine-tRNA ligase activity
H9L11_RS04480	COG0456	acetyltransferase
H9L11_RS04510	COG0540	Belongs to the ATCase OTCase family
H9L11_RS04515	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
H9L11_RS04520	COG0251	oxidation-reduction process
H9L11_RS04525	COG0204	Acyl-transferase
H9L11_RS04530	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
H9L11_RS04535	COG5007	Belongs to the BolA IbaG family
H9L11_RS04545	COG2854	intermembrane phospholipid transfer
H9L11_RS04550	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
H9L11_RS04555	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
H9L11_RS04560	COG1127	ABC transporter
H9L11_RS04570	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
H9L11_RS04570	COG0517	IMP dehydrogenase activity
H9L11_RS04580	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
H9L11_RS04585	COG1137	ATPase activity
H9L11_RS04595	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
H9L11_RS04600	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H9L11_RS04605	COG1660	Displays ATPase and GTPase activities
H9L11_RS04610	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H9L11_RS04615	COG2239	Acts as a magnesium transporter
H9L11_RS04620	COG0312	modulator of DNA gyrase
H9L11_RS04625	COG3028	Belongs to the UPF0307 family
H9L11_RS04630	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
H9L11_RS04635	COG0564	pseudouridine synthase activity
H9L11_RS04645	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
H9L11_RS04650	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
H9L11_RS04655	COG0312	modulator of DNA gyrase
H9L11_RS04660	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H9L11_RS04665	COG3164	Protein of unknown function
H9L11_RS04675	COG0424	maF-like protein
H9L11_RS04680	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
H9L11_RS04685	COG1792	Involved in formation and maintenance of cell shape
H9L11_RS04690	COG1077	Cell shape determining protein MreB Mrl
H9L11_RS04710	COG3267	Type II secretory pathway component ExeA
H9L11_RS04710	COG3409	Peptidoglycan-binding domain 1 protein
H9L11_RS04715	COG1450	Type ii and iii secretion system protein
H9L11_RS04735	COG2200	EAL domain
H9L11_RS04735	COG2199	diguanylate cyclase activity
H9L11_RS04740	COG0629	single-stranded DNA binding
H9L11_RS04755	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
H9L11_RS04765	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
H9L11_RS04770	COG0527	aspartate kinase activity
H9L11_RS04775	COG1410	methionine synthase
H9L11_RS04775	COG0646	methionine synthase
H9L11_RS04835	COG0175	sulfate reduction
H9L11_RS04840	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H9L11_RS04845	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
H9L11_RS04865	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H9L11_RS04870	COG0735	belongs to the Fur family
H9L11_RS04880	COG0166	Belongs to the GPI family
H9L11_RS04885	COG0432	Pfam Uncharacterised protein family UPF0047
H9L11_RS04890	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
H9L11_RS04915	COG2965	DNA replication, synthesis of RNA primer
H9L11_RS04920	COG0360	Binds together with S18 to 16S ribosomal RNA
H9L11_RS04925	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
H9L11_RS04930	COG0338	D12 class N6 adenine-specific DNA methyltransferase
H9L11_RS04940	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
H9L11_RS04945	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
H9L11_RS04975	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
H9L11_RS04985	COG0678	peroxiredoxin activity
H9L11_RS04985	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
H9L11_RS04990	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H9L11_RS05000	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
H9L11_RS05000	COG0165	Argininosuccinate lyase
H9L11_RS05005	COG0137	argininosuccinate synthase activity
H9L11_RS05015	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
H9L11_RS05025	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
H9L11_RS05035	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
H9L11_RS05040	COG0460	homoserine dehydrogenase
H9L11_RS05040	COG0527	aspartate kinase activity
H9L11_RS05045	COG0626	cystathionine gamma-synthase activity
H9L11_RS05050	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
H9L11_RS05055	COG0281	malic enzyme
H9L11_RS05070	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
H9L11_RS05075	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
H9L11_RS05095	COG2923	Belongs to the DsrF TusC family
H9L11_RS05100	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
H9L11_RS05105	COG2964	Protein conserved in bacteria
H9L11_RS05110	COG0545	Peptidyl-prolyl cis-trans isomerase
H9L11_RS05125	COG1446	asparaginase
H9L11_RS05130	COG1047	Peptidyl-prolyl cis-trans
H9L11_RS05145	COG2249	NAD(P)H dehydrogenase (quinone) activity
H9L11_RS05150	COG0488	(ABC) transporter
H9L11_RS05160	COG0429	hydrolase of the alpha beta-hydrolase fold
H9L11_RS05170	COG3954	Phosphoribulokinase
H9L11_RS05175	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H9L11_RS05195	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H9L11_RS05200	COG0512	Glutamine amidotransferase of anthranilate synthase
H9L11_RS05210	COG0697	spore germination
H9L11_RS05220	COG1473	amidohydrolase
H9L11_RS05225	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
H9L11_RS05230	COG0583	DNA-binding transcription factor activity
H9L11_RS05245	COG0180	Tryptophanyl-tRNA synthetase
H9L11_RS05250	COG0546	phosphoglycolate phosphatase activity
H9L11_RS05255	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H9L11_RS05260	COG0557	exoribonuclease II activity
H9L11_RS05265	COG1959	2 iron, 2 sulfur cluster binding
H9L11_RS05270	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H9L11_RS05270	COG1017	nitric oxide dioxygenase activity
H9L11_RS05275	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
H9L11_RS05280	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
H9L11_RS05285	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
H9L11_RS05290	COG0330	HflC and HflK could
H9L11_RS05295	COG0330	HflC and HflK could
H9L11_RS05300	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
H9L11_RS05310	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
H9L11_RS05315	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
H9L11_RS05325	COG0802	atpase or kinase
H9L11_RS05330	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
H9L11_RS05395	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
H9L11_RS05400	COG1162	GTPase activity
H9L11_RS05405	COG0688	phosphatidylethanolamine metabolic process
H9L11_RS05410	COG0471	metal ion transport
H9L11_RS05410	COG3273	potassium ion transport
H9L11_RS05420	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
H9L11_RS05425	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H9L11_RS05430	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
H9L11_RS05435	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
H9L11_RS05440	COG1045	serine acetyltransferase
H9L11_RS05445	COG4942	peptidase
H9L11_RS05465	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
H9L11_RS05470	COG1053	succinate dehydrogenase
H9L11_RS05475	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
H9L11_RS05480	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
H9L11_RS05485	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
H9L11_RS05500	COG1509	lysine 2,3-aminomutase activity
H9L11_RS05505	COG1285	pathogenesis
H9L11_RS05515	COG0459	protein refolding
H9L11_RS05525	COG0534	Mate efflux family protein
H9L11_RS05530	COG0205	6-phosphofructokinase activity
H9L11_RS05540	COG3678	ATP-independent chaperone mediated protein folding
H9L11_RS05545	COG0745	RESPONSE REGULATOR receiver
H9L11_RS05550	COG2205	protein histidine kinase activity
H9L11_RS05560	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
H9L11_RS05565	COG3030	protein affecting phage T7 exclusion by the F plasmid
H9L11_RS05570	COG1027	Aspartate ammonia-lyase
H9L11_RS05575	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
H9L11_RS05580	COG4232	protein-disulfide reductase activity
H9L11_RS05590	COG3263	regulation of cellular component size
H9L11_RS05600	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H9L11_RS05625	COG2814	Major facilitator Superfamily
H9L11_RS05640	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H9L11_RS05645	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
H9L11_RS05650	COG0511	ligase activity, forming carbon-carbon bonds
H9L11_RS05655	COG0439	Biotin carboxylase
H9L11_RS05660	COG2264	protein methyltransferase activity
H9L11_RS05665	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H9L11_RS05670	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
H9L11_RS05680	COG0488	(ABC) transporter
H9L11_RS05730	COG1982	Orn Lys Arg decarboxylase major
H9L11_RS05735	COG0531	amino acid
H9L11_RS05740	COG3710	Transcriptional regulator
H9L11_RS05745	COG0789	Transcriptional regulator
H9L11_RS05755	COG0151	Belongs to the GarS family
H9L11_RS05770	COG1253	flavin adenine dinucleotide binding
H9L11_RS05775	COG3068	Protein conserved in bacteria
H9L11_RS05785	COG1573	uracil-dna glycosylase
H9L11_RS05790	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
H9L11_RS05795	COG2816	NAD+ diphosphatase activity
H9L11_RS05800	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
H9L11_RS05805	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
H9L11_RS05810	COG0085	RNA polymerase activity
H9L11_RS05815	COG0222	ribosome binding
H9L11_RS05820	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
H9L11_RS05835	COG0250	Participates in transcription elongation, termination and antitermination
H9L11_RS05840	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
H9L11_RS05845	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
H9L11_RS05875	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
H9L11_RS05875	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
H9L11_RS05880	COG0812	UDP-N-acetylmuramate dehydrogenase activity
H9L11_RS05890	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H9L11_RS05965	COG4206	TonB-dependent receptor
H9L11_RS06010	COG2856	Zn peptidase
H9L11_RS06020	COG0328	RNA-DNA hybrid ribonuclease activity
H9L11_RS06025	COG2003	Belongs to the UPF0758 family
H9L11_RS06085	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H9L11_RS06090	COG0534	Mate efflux family protein
H9L11_RS06095	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
H9L11_RS06100	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
H9L11_RS06105	COG2937	Belongs to the GPAT DAPAT family
H9L11_RS06110	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
H9L11_RS06115	COG3161	chorismate lyase activity
H9L11_RS06120	COG1580	Controls the rotational direction of flagella during chemotaxis
H9L11_RS06125	COG0705	Rhomboid family
H9L11_RS06130	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H9L11_RS06140	COG2177	Part of the ABC transporter FtsEX involved in
H9L11_RS06145	COG2884	Cell division ATP-binding protein ftsE
H9L11_RS06150	COG0552	protein localization to endoplasmic reticulum
H9L11_RS06155	COG0742	ribosomal rna small subunit methyltransferase
H9L11_RS06165	COG2095	MarC family integral membrane protein
H9L11_RS06210	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
H9L11_RS06215	COG0640	Transcriptional regulator
H9L11_RS06220	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
H9L11_RS06225	COG1280	lysine exporter protein (LysE YggA)
H9L11_RS06230	COG2267	carboxylic ester hydrolase activity
H9L11_RS06235	COG0561	phosphatase activity
H9L11_RS06250	COG3148	PFAM DTW domain containing protein
H9L11_RS06255	COG3287	FIST C domain
H9L11_RS06255	COG2199	diguanylate cyclase activity
H9L11_RS06255	COG2200	EAL domain
H9L11_RS06260	COG1011	Hydrolase
H9L11_RS06265	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
H9L11_RS06275	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
H9L11_RS06280	COG0019	diaminopimelate decarboxylase activity
H9L11_RS06290	COG1965	Belongs to the frataxin family
H9L11_RS06295	COG3072	Adenylate cyclase
H9L11_RS06300	COG0181	hydroxymethylbilane synthase activity
H9L11_RS06305	COG1587	Uroporphyrinogen-III synthase
H9L11_RS06310	COG2959	enzyme of heme biosynthesis
H9L11_RS06315	COG3071	HemY protein
H9L11_RS06355	COG0633	Ferredoxin
H9L11_RS06360	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
H9L11_RS06375	COG3118	belongs to the thioredoxin family
H9L11_RS06380	COG0513	Belongs to the DEAD box helicase family
H9L11_RS06385	COG0248	Ppx GppA phosphatase
H9L11_RS06395	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
H9L11_RS06405	COG0514	ATP-dependent DNA helicase (RecQ)
H9L11_RS06410	COG2962	Rard protein
H9L11_RS06420	COG1280	lysine exporter protein (LysE YggA)
H9L11_RS06425	COG0405	Gamma-glutamyltransferase
H9L11_RS06430	COG0210	DNA helicase
H9L11_RS06440	COG3220	belongs to the UPF0276 family
H9L11_RS06470	COG0006	proline dipeptidase activity
H9L11_RS06470	COG0006	proline dipeptidase activity
H9L11_RS06485	COG2104	thiamine diphosphate biosynthetic process
H9L11_RS06490	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
H9L11_RS06555	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
H9L11_RS06575	COG0009	L-threonylcarbamoyladenylate synthase
H9L11_RS06580	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
H9L11_RS06585	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
H9L11_RS06590	COG0551	DNA topoisomerase type I activity
H9L11_RS06595	COG2922	Belongs to the Smg family
H9L11_RS06600	COG0758	DNA mediated transformation
H9L11_RS06610	COG0242	peptide deformylase activity
H9L11_RS06615	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
H9L11_RS06620	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
H9L11_RS06620	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
H9L11_RS06625	COG0569	domain protein
H9L11_RS06630	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
H9L11_RS06640	COG1272	protein, Hemolysin III
H9L11_RS06645	COG4326	sporulation control protein
H9L11_RS06655	COG3084	Protein conserved in bacteria
H9L11_RS06665	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
H9L11_RS06670	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H9L11_RS06675	COG0204	Acyl-transferase
H9L11_RS06720	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
H9L11_RS06735	COG3978	acetolactate synthase activity
H9L11_RS06740	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H9L11_RS06745	COG0129	dihydroxy-acid dehydratase activity
H9L11_RS06755	COG0583	DNA-binding transcription factor activity
H9L11_RS06760	COG2814	Major facilitator Superfamily
H9L11_RS06770	COG0765	amino acid transport
H9L11_RS06780	COG0355	proton-transporting ATP synthase activity, rotational mechanism
H9L11_RS06785	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
H9L11_RS06790	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
H9L11_RS06795	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
H9L11_RS06800	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
H9L11_RS06805	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
H9L11_RS06815	COG0356	it plays a direct role in the translocation of protons across the membrane
H9L11_RS06820	COG3312	ion transport
H9L11_RS06825	COG1475	DNA binding
H9L11_RS06830	COG1192	Involved in chromosome partitioning
H9L11_RS06835	COG0357	Ribosomal RNA small subunit methyltransferase G
H9L11_RS06840	COG0445	tRNA wobble uridine modification
H9L11_RS06845	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
H9L11_RS06855	COG0706	membrane insertase activity
H9L11_RS06865	COG0594	ribonuclease P activity
H9L11_RS06875	COG1126	abc transporter atp-binding protein
H9L11_RS06890	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
H9L11_RS06895	COG0592	DNA-directed DNA polymerase activity
H9L11_RS06905	COG0187	DNA topoisomerase II activity
H9L11_RS06915	COG0071	Belongs to the small heat shock protein (HSP20) family
H9L11_RS06920	COG3977	Valine--pyruvate aminotransferase
H9L11_RS06925	COG0366	Alpha amylase catalytic
H9L11_RS06940	COG2119	membrane
H9L11_RS06950	COG0425	Belongs to the sulfur carrier protein TusA family
H9L11_RS06965	COG0604	alcohol dehydrogenase
H9L11_RS06970	COG0183	Belongs to the thiolase family
H9L11_RS06980	COG1739	Uncharacterized protein family UPF0029
H9L11_RS06985	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
H9L11_RS07025	COG0583	DNA-binding transcription factor activity
H9L11_RS07030	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
H9L11_RS07035	COG2960	long-chain fatty acid transporting porin activity
H9L11_RS07040	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H9L11_RS07045	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H9L11_RS07100	COG4166	transmembrane transport
H9L11_RS07105	COG0601	transmembrane transport
H9L11_RS07110	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H9L11_RS07120	COG1609	Transcriptional regulator
H9L11_RS07125	COG0583	DNA-binding transcription factor activity
H9L11_RS07140	COG0129	dihydroxy-acid dehydratase activity
H9L11_RS07145	COG3265	gluconokinase activity
H9L11_RS07150	COG2610	gluconate transmembrane transporter activity
H9L11_RS07155	COG0800	Aldolase
H9L11_RS07160	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
H9L11_RS07165	COG0583	DNA-binding transcription factor activity
H9L11_RS07170	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H9L11_RS07175	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
H9L11_RS07185	COG1522	sequence-specific DNA binding
H9L11_RS07190	COG5001	Diguanylate cyclase
H9L11_RS07190	COG5002	protein histidine kinase activity
H9L11_RS07195	COG0742	ribosomal rna small subunit methyltransferase
H9L11_RS07210	COG0589	response to stress
H9L11_RS07215	COG1528	Iron-storage protein
H9L11_RS07225	COG2081	HI0933 family
H9L11_RS07255	COG1597	lipid kinase activity
H9L11_RS07285	COG0628	permease
H9L11_RS07300	COG1322	Protein conserved in bacteria
H9L11_RS07305	COG2226	methyltransferase
H9L11_RS07310	COG3165	ubiquinone biosynthetic process from chorismate
H9L11_RS07315	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
H9L11_RS07325	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
H9L11_RS07330	COG0805	protein transport
H9L11_RS07340	COG0084	hydrolase, TatD family'
H9L11_RS07350	COG0456	acetyltransferase
H9L11_RS07355	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H9L11_RS07355	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H9L11_RS07360	COG0218	Necessary for normal cell division and for the maintenance of normal septation
H9L11_RS07390	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
H9L11_RS07400	COG2204	response regulator
H9L11_RS07405	COG3852	Histidine kinase
H9L11_RS07415	COG0174	glutamine synthetase
H9L11_RS07420	COG1217	gtp-binding protein TYPA
H9L11_RS07425	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
H9L11_RS07435	COG1295	ribonuclease BN
H9L11_RS07440	COG1490	D-aminoacyl-tRNA deacylase activity
H9L11_RS07445	COG0456	acetyltransferase
H9L11_RS07455	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
H9L11_RS07460	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
H9L11_RS07465	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
H9L11_RS07470	COG3031	protein transport across the cell outer membrane
H9L11_RS07480	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
H9L11_RS07485	COG1459	type II secretion system
H9L11_RS07490	COG2165	general secretion pathway protein
H9L11_RS07495	COG2165	general secretion pathway protein
H9L11_RS07500	COG2165	general secretion pathway protein
H9L11_RS07505	COG4795	General secretion pathway protein
H9L11_RS07510	COG3156	type II secretion system protein K
H9L11_RS07515	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
H9L11_RS07520	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
H9L11_RS07530	COG1218	3'(2'),5'-bisphosphate nucleotidase
H9L11_RS07535	COG0494	nUDIX hydrolase
H9L11_RS07545	COG1040	competence protein
H9L11_RS07560	COG2183	response to ionizing radiation
H9L11_RS07570	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
H9L11_RS07590	COG2233	PERMEase
H9L11_RS07595	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
H9L11_RS07600	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H9L11_RS07605	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H9L11_RS07610	COG1758	RNA polymerase activity
H9L11_RS07615	COG0194	GDP metabolic process
H9L11_RS07630	COG0848	biopolymer transport protein
H9L11_RS07635	COG0811	peptide transport
H9L11_RS07655	COG4174	ABC transporter (Permease)
H9L11_RS07660	COG4239	(ABC) transporter, permease
H9L11_RS07665	COG0747	negative chemotaxis
H9L11_RS07670	COG0444	Belongs to the ABC transporter superfamily
H9L11_RS07675	COG4608	Belongs to the ABC transporter superfamily
H9L11_RS07710	COG0328	RNA-DNA hybrid ribonuclease activity
H9L11_RS07715	COG1968	undecaprenyl-diphosphatase activity
H9L11_RS07725	COG0668	transmembrane transport
H9L11_RS07745	COG0745	RESPONSE REGULATOR receiver
H9L11_RS07750	COG1716	ATPase activity
H9L11_RS07750	COG5001	Diguanylate cyclase
H9L11_RS07790	COG2003	Belongs to the UPF0758 family
H9L11_RS07805	COG1561	YicC-like family, N-terminal region
H9L11_RS07810	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
H9L11_RS07815	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
H9L11_RS07820	COG1560	Kdo2-lipid A biosynthetic process
H9L11_RS07825	COG1309	transcriptional regulator
H9L11_RS07830	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
H9L11_RS07840	COG2003	Belongs to the UPF0758 family
H9L11_RS07875	COG0438	transferase activity, transferring glycosyl groups
H9L11_RS07880	COG0463	Glycosyl transferase, family 2
H9L11_RS07885	COG0859	PFAM glycosyl transferase family 9
H9L11_RS07890	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
H9L11_RS07895	COG3642	lipopolysaccharide core region biosynthetic process
H9L11_RS07900	COG1083	cytidylyl-transferase
H9L11_RS07910	COG0728	peptidoglycan biosynthetic process
H9L11_RS07925	COG0367	asparagine synthase
H9L11_RS07940	COG1519	Transferase
H9L11_RS07945	COG0859	PFAM glycosyl transferase family 9
H9L11_RS07955	COG1560	Kdo2-lipid A biosynthetic process
H9L11_RS07965	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H9L11_RS07985	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
H9L11_RS07990	COG2895	sulfate adenylyltransferase (ATP) activity
H9L11_RS08000	COG0529	Catalyzes the synthesis of activated sulfate
H9L11_RS08005	COG0175	sulfate reduction
H9L11_RS08010	COG0471	metal ion transport
H9L11_RS08010	COG0490	domain, Protein
H9L11_RS08060	COG3023	N-Acetylmuramoyl-L-alanine amidase
H9L11_RS08120	COG1682	transport, permease protein
H9L11_RS08140	COG0149	triose-phosphate isomerase activity
H9L11_RS08165	COG1494	fructose-1,6-bisphosphatase
H9L11_RS08175	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
H9L11_RS08180	COG1575	Belongs to the MenA family. Type 1 subfamily
H9L11_RS08185	COG3335	DDE superfamily endonuclease
H9L11_RS08215	COG2003	Belongs to the UPF0758 family
H9L11_RS08225	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
H9L11_RS08230	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
H9L11_RS08235	COG3335	DDE superfamily endonuclease
H9L11_RS08245	COG1609	Transcriptional regulator
H9L11_RS08250	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
H9L11_RS08255	COG0254	rRNA binding
H9L11_RS08265	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
H9L11_RS08270	COG0088	Forms part of the polypeptide exit tunnel
H9L11_RS08280	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
H9L11_RS08285	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
H9L11_RS08290	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
H9L11_RS08295	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
H9L11_RS08305	COG0255	Belongs to the universal ribosomal protein uL29 family
H9L11_RS08310	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
H9L11_RS08320	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
H9L11_RS08325	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
H9L11_RS08335	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
H9L11_RS08340	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
H9L11_RS08355	COG1841	ribosomal large subunit assembly
H9L11_RS08360	COG0200	Binds to the 23S rRNA
H9L11_RS08365	COG0201	protein transport
H9L11_RS08370	COG0257	Belongs to the bacterial ribosomal protein bL36 family
H9L11_RS08375	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
H9L11_RS08380	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
H9L11_RS08390	COG0202	RNA polymerase activity
H9L11_RS08395	COG0203	ribosomal protein L17
H9L11_RS08405	COG0545	Peptidyl-prolyl cis-trans isomerase
H9L11_RS08415	COG2153	protein acetylation
H9L11_RS08420	COG0513	Belongs to the DEAD box helicase family
H9L11_RS08435	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
H9L11_RS08435	COG1648	precorrin-2 dehydrogenase activity
H9L11_RS08440	COG0175	sulfate reduction
H9L11_RS08445	COG2895	sulfate adenylyltransferase (ATP) activity
H9L11_RS08450	COG3273	potassium ion transport
H9L11_RS08450	COG0471	metal ion transport
H9L11_RS08455	COG0529	Catalyzes the synthesis of activated sulfate
H9L11_RS08475	COG4181	ATPase activity
H9L11_RS08490	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
H9L11_RS08500	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
H9L11_RS08505	COG0729	surface antigen
H9L11_RS08510	COG2911	Protein conserved in bacteria
H9L11_RS08515	COG2105	PFAM AIG2 family protein
H9L11_RS08525	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
H9L11_RS08530	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
H9L11_RS08535	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
H9L11_RS08540	COG0163	prenyltransferase activity
H9L11_RS08550	COG1178	ABC-type Fe3 transport system permease component
H9L11_RS08555	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
H9L11_RS08560	COG0583	DNA-binding transcription factor activity
H9L11_RS08565	COG1902	pentaerythritol trinitrate reductase activity
H9L11_RS08580	COG2358	TRAP transporter, solute receptor (TAXI family
H9L11_RS08600	COG0142	geranyltranstransferase activity
H9L11_RS08605	COG0261	This protein binds to 23S rRNA in the presence of protein L20
H9L11_RS08615	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
H9L11_RS08620	COG2966	Psort location CytoplasmicMembrane, score
H9L11_RS08635	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
H9L11_RS08640	COG2967	ApaG domain
H9L11_RS08645	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
H9L11_RS08650	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
H9L11_RS08655	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H9L11_RS08660	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
H9L11_RS08665	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
H9L11_RS08685	COG0473	3-isopropylmalate dehydrogenase activity
H9L11_RS08690	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
H9L11_RS08710	COG0583	DNA-binding transcription factor activity
H9L11_RS08715	COG1022	Amp-dependent synthetase and ligase
H9L11_RS08720	COG0028	Belongs to the TPP enzyme family
H9L11_RS08725	COG0440	acetolactate synthase activity
H9L11_RS08740	COG0469	pyruvate kinase activity
H9L11_RS08745	COG1349	DNA-binding transcription factor activity
H9L11_RS08750	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
H9L11_RS08760	COG2376	Dihydroxyacetone kinase
H9L11_RS08765	COG1461	Dihydroxyacetone kinase
H9L11_RS08770	COG3335	DDE superfamily endonuclease
H9L11_RS08785	COG3722	fumarate hydratase activity
H9L11_RS08795	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
H9L11_RS08795	COG2213	PTS system mannitol-specific
H9L11_RS08845	COG0358	DNA primase activity
H9L11_RS08850	COG1610	YqeY-like protein
H9L11_RS08855	COG0828	Belongs to the bacterial ribosomal protein bS21 family
H9L11_RS08860	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
H9L11_RS08865	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H9L11_RS08870	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
H9L11_RS08875	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
H9L11_RS08880	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
H9L11_RS08885	COG1968	undecaprenyl-diphosphatase activity
H9L11_RS08895	COG3409	Peptidoglycan-binding domain 1 protein
H9L11_RS08895	COG3267	Type II secretory pathway component ExeA
H9L11_RS08905	COG0405	Gamma-glutamyltransferase
H9L11_RS08910	COG4991	sh3 domain protein
H9L11_RS08915	COG0306	phosphate transporter
H9L11_RS08920	COG1392	Phosphate transport regulator
H9L11_RS08925	COG3025	triphosphatase activity
H9L11_RS08940	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
H9L11_RS08945	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
H9L11_RS08945	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
H9L11_RS08950	COG1538	Outer membrane efflux protein
H9L11_RS08955	COG0494	nUDIX hydrolase
H9L11_RS08960	COG3151	Protein conserved in bacteria
H9L11_RS08970	COG3150	esterase
H9L11_RS08980	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
H9L11_RS08985	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H9L11_RS08995	COG3105	Protein conserved in bacteria
H9L11_RS09000	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
H9L11_RS09010	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
H9L11_RS09015	COG0723	plastoquinol--plastocyanin reductase activity
H9L11_RS09020	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
H9L11_RS09025	COG2857	Cytochrome c1
H9L11_RS09030	COG0625	glutathione transferase activity
H9L11_RS09035	COG2969	positive regulation of protein catabolic process
H9L11_RS09040	COG2823	Periplasmic or secreted lipoprotein
H9L11_RS09045	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
H9L11_RS09060	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
H9L11_RS09080	COG3116	cell division
H9L11_RS09085	COG0768	penicillin binding
H9L11_RS09090	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
H9L11_RS09095	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
H9L11_RS09100	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
H9L11_RS09105	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
H9L11_RS09110	COG0772	Belongs to the SEDS family
H9L11_RS09125	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
H9L11_RS09130	COG0849	cell division
H9L11_RS09135	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
H9L11_RS09140	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
H9L11_RS09150	COG0653	protein targeting
H9L11_RS09155	COG0494	nUDIX hydrolase
H9L11_RS09165	COG0505	Belongs to the CarA family
H9L11_RS09170	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
H9L11_RS09185	COG0730	response to heat
H9L11_RS09190	COG0583	DNA-binding transcription factor activity
H9L11_RS09195	COG2860	membrane
H9L11_RS09210	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
H9L11_RS09220	COG0493	'glutamate synthase
H9L11_RS09225	COG0070	glutamate synthase
H9L11_RS09225	COG0069	glutamate synthase activity
H9L11_RS09225	COG0067	glutamate synthase
H9L11_RS09235	COG0070	glutamate synthase
H9L11_RS09235	COG0069	glutamate synthase activity
H9L11_RS09235	COG0067	glutamate synthase
H9L11_RS09240	COG1242	4 iron, 4 sulfur cluster binding
H9L11_RS09245	COG5001	Diguanylate cyclase
H9L11_RS09245	COG4251	negative regulation of phosphorylation
H9L11_RS09245	COG3706	GGDEF domain
H9L11_RS09245	COG2203	Gaf domain
H9L11_RS09250	COG0784	Response regulator, receiver
H9L11_RS09250	COG5002	protein histidine kinase activity
H9L11_RS09250	COG2198	Histidine kinase
H9L11_RS09260	COG0745	RESPONSE REGULATOR receiver
H9L11_RS09270	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
H9L11_RS09290	COG0083	homoserine kinase activity
H9L11_RS09295	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
H9L11_RS09305	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
H9L11_RS09310	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
H9L11_RS09315	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
H9L11_RS09330	COG1115	amino acid carrier protein
H9L11_RS09335	COG3022	response to hydroperoxide
H9L11_RS09340	COG0513	Belongs to the DEAD box helicase family
H9L11_RS09345	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
H9L11_RS09355	COG0716	FMN binding
H9L11_RS09360	COG4974	Belongs to the 'phage' integrase family
H9L11_RS09365	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H9L11_RS09370	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
H9L11_RS09385	COG2204	response regulator
H9L11_RS09395	COG0667	Aldo Keto reductase
H9L11_RS09420	COG0730	response to heat
H9L11_RS09425	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
H9L11_RS09430	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
H9L11_RS09440	COG1283	sodium-dependent phosphate transmembrane transporter activity
H9L11_RS09445	COG0583	DNA-binding transcription factor activity
H9L11_RS09450	COG0640	Transcriptional regulator
H9L11_RS09455	COG0268	Binds directly to 16S ribosomal RNA
H9L11_RS09460	COG0728	peptidoglycan biosynthetic process
H9L11_RS09465	COG0196	riboflavin kinase activity
H9L11_RS09480	COG1047	Peptidyl-prolyl cis-trans
H9L11_RS09485	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
H9L11_RS09495	COG3279	Response regulator of the LytR AlgR family
H9L11_RS09500	COG3275	phosphorelay sensor kinase activity
H9L11_RS09505	COG1966	Carbon starvation protein
H9L11_RS09525	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
H9L11_RS09530	COG1472	Belongs to the glycosyl hydrolase 3 family
H9L11_RS09535	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
H9L11_RS09540	COG0287	Prephenate dehydrogenase
H9L11_RS09540	COG1605	Chorismate mutase
H9L11_RS09545	COG0739	heme binding
H9L11_RS09555	COG0488	(ABC) transporter
H9L11_RS09565	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
H9L11_RS09570	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
H9L11_RS09575	COG1605	Chorismate mutase
H9L11_RS09575	COG0077	Prephenate dehydratase
H9L11_RS09580	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
H9L11_RS09590	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H9L11_RS09595	COG0564	pseudouridine synthase activity
H9L11_RS09605	COG0542	response to heat
H9L11_RS09660	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
H9L11_RS09665	COG0826	peptidase U32
H9L11_RS09670	COG2974	May be involved in recombination
H9L11_RS09675	COG0745	RESPONSE REGULATOR receiver
H9L11_RS09680	COG5002	protein histidine kinase activity
H9L11_RS09690	COG0248	Ppx GppA phosphatase
H9L11_RS09695	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
H9L11_RS09700	COG0573	inorganic phosphate transmembrane transporter activity
H9L11_RS09705	COG0581	inorganic phosphate transmembrane transporter activity
H9L11_RS09710	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
H9L11_RS09715	COG0704	Plays a role in the regulation of phosphate uptake
H9L11_RS09725	COG3142	Participates in the control of copper homeostasis
H9L11_RS09730	COG0450	alkyl hydroperoxide reductase
H9L11_RS09735	COG0583	DNA-binding transcription factor activity
H9L11_RS09740	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
H9L11_RS09750	COG0517	IMP dehydrogenase activity
H9L11_RS09760	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
H9L11_RS09770	COG1862	Preprotein translocase
H9L11_RS09775	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H9L11_RS09780	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H9L11_RS09795	COG0483	inositol monophosphate 1-phosphatase activity
H9L11_RS09800	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
H9L11_RS09810	COG1104	cysteine desulfurase activity
H9L11_RS09815	COG0822	iron-sulfur transferase activity
H9L11_RS09830	COG0443	Heat shock 70 kDa protein
H9L11_RS09835	COG0633	Ferredoxin
H9L11_RS09840	COG2975	iron-sulfur cluster assembly
H9L11_RS09850	COG0105	UTP biosynthetic process
H9L11_RS09865	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
H9L11_RS09870	COG0124	histidyl-tRNA synthetase
H9L11_RS09875	COG2976	Protein conserved in bacteria
H9L11_RS09880	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H9L11_RS09885	COG1160	GTP binding
H9L11_RS09905	COG0516	GMP reductase activity
H9L11_RS09905	COG0517	IMP dehydrogenase activity
H9L11_RS09910	COG0519	Catalyzes the synthesis of GMP from XMP
H9L11_RS09910	COG0518	GMP synthase (glutamine-hydrolyzing) activity
H9L11_RS09915	COG0582	viral genome integration into host DNA
H9L11_RS09935	COG3335	DDE superfamily endonuclease
H9L11_RS09995	COG3335	DDE superfamily endonuclease
H9L11_RS10060	COG1757	Na H antiporter
H9L11_RS10070	COG1584	GPR1 FUN34 yaaH family protein
H9L11_RS10075	COG1115	amino acid carrier protein
H9L11_RS10090	COG2873	o-acetylhomoserine
H9L11_RS10095	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
H9L11_RS10115	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H9L11_RS10115	COG3153	acetyltransferase
H9L11_RS10120	COG0583	DNA-binding transcription factor activity
H9L11_RS10155	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
H9L11_RS10215	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
H9L11_RS10220	COG2867	negative regulation of translational initiation
H9L11_RS10225	COG2914	Belongs to the UPF0125 (RnfH) family
H9L11_RS10230	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H9L11_RS10240	COG0497	DNA recombination
H9L11_RS10250	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
H9L11_RS10255	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
H9L11_RS10260	COG1301	dicarboxylic acid transport
H9L11_RS10270	COG0484	heat shock protein binding
H9L11_RS10300	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
H9L11_RS10310	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
H9L11_RS10315	COG0047	phosphoribosylformylglycinamidine synthase activity
H9L11_RS10315	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
H9L11_RS10330	COG1629	transport
H9L11_RS10345	COG2195	Cleaves the N-terminal amino acid of tripeptides
H9L11_RS10350	COG2252	PERMEase
H9L11_RS10355	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
H9L11_RS10360	COG1073	alpha beta
H9L11_RS10370	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
H9L11_RS10375	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
H9L11_RS10380	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
H9L11_RS10385	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H9L11_RS10385	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H9L11_RS10400	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
H9L11_RS10410	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
H9L11_RS10415	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
H9L11_RS10425	COG0142	geranyltranstransferase activity
H9L11_RS10430	COG1722	exodeoxyribonuclease VII activity
H9L11_RS10435	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
H9L11_RS10445	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H9L11_RS10445	COG0301	tRNA thio-modification
H9L11_RS10450	COG0583	DNA-binding transcription factor activity
H9L11_RS10460	COG2363	Small membrane protein
H9L11_RS10470	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H9L11_RS10475	COG1611	Belongs to the LOG family
H9L11_RS10490	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
H9L11_RS10490	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
H9L11_RS10500	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
H9L11_RS10505	COG1464	Belongs to the NlpA lipoprotein family
H9L11_RS10510	COG2011	ABC-type metal ion transport system permease component
H9L11_RS10515	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
H9L11_RS10520	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
H9L11_RS10530	COG1263	PTS System
H9L11_RS10530	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9L11_RS10535	COG0366	Alpha amylase catalytic
H9L11_RS10550	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H9L11_RS10555	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
H9L11_RS10560	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
H9L11_RS10565	COG0321	lipoyl(octanoyl) transferase activity
H9L11_RS10575	COG1686	Belongs to the peptidase S11 family
H9L11_RS10580	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
H9L11_RS10585	COG0772	Belongs to the SEDS family
H9L11_RS10590	COG0768	penicillin binding
H9L11_RS10595	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
H9L11_RS10600	COG0799	negative regulation of ribosome biogenesis
H9L11_RS10605	COG1466	dna polymerase III delta subunit
H9L11_RS10610	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
H9L11_RS10615	COG0495	leucyl-tRNA aminoacylation
H9L11_RS10620	COG2888	peptidyl-tyrosine sulfation
H9L11_RS10625	COG0815	Transfers the fatty acyl group on membrane lipoproteins
H9L11_RS10630	COG4535	Mg2 and Co2 transporter CorC
H9L11_RS10635	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
H9L11_RS10640	COG1702	phosphate starvation-inducible protein PhoH
H9L11_RS10645	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
H9L11_RS10650	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H9L11_RS10755	COG0012	GTP binding
H9L11_RS10760	COG0193	aminoacyl-tRNA hydrolase activity
H9L11_RS10765	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
H9L11_RS10770	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
H9L11_RS10775	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
H9L11_RS10780	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
H9L11_RS10790	COG2890	protein-(glutamine-N5) methyltransferase activity
H9L11_RS10795	COG3094	Invasion gene expression up-regulator, SirB
H9L11_RS10800	COG2912	Transglutaminase-like superfamily
H9L11_RS10805	COG2877	3-deoxy-8-phosphooctulonate synthase activity
H9L11_RS10810	COG0737	Belongs to the 5'-nucleotidase family
H9L11_RS10815	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
H9L11_RS10820	COG1187	pseudouridine synthase activity
H9L11_RS10825	COG2840	Smr protein MutS2
H9L11_RS10865	COG2608	mercury ion transmembrane transporter activity
H9L11_RS10865	COG2217	Heavy metal translocating P-type atpase
H9L11_RS10875	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
H9L11_RS10925	COG0835	chemotaxis
H9L11_RS10925	COG0784	Response regulator, receiver
H9L11_RS10930	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
H9L11_RS10935	COG1815	bacterial-type flagellum-dependent cell motility
H9L11_RS10940	COG1558	bacterial-type flagellum-dependent cell motility
H9L11_RS10950	COG1749	Flagellar hook protein flgE
H9L11_RS10955	COG4787	bacterial-type flagellum-dependent cell motility
H9L11_RS10965	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
H9L11_RS10970	COG1706	bacterial-type flagellum-dependent cell motility
H9L11_RS10975	COG3951	Flagellar rod assembly protein muramidase FlgJ
H9L11_RS10975	COG1705	Flagellar rod assembly protein muramidase FlgJ
H9L11_RS10985	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
H9L11_RS10990	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
H9L11_RS10995	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
H9L11_RS11000	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
H9L11_RS11005	COG2190	(PTS) system
H9L11_RS11010	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
H9L11_RS11015	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H9L11_RS11020	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
H9L11_RS11025	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
H9L11_RS11030	COG3115	cell septum assembly
H9L11_RS11035	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
H9L11_RS11055	COG0330	HflC and HflK could
H9L11_RS11060	COG3118	belongs to the thioredoxin family
H9L11_RS11065	COG0300	oxidoreductase activity
H9L11_RS11070	COG1090	epimerase
H9L11_RS11100	COG0622	Phosphoesterase
H9L11_RS11120	COG3710	Transcriptional regulator
H9L11_RS11125	COG0326	Molecular chaperone. Has ATPase activity
H9L11_RS11135	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
H9L11_RS11140	COG3104	oligopeptide transport
H9L11_RS11145	COG0250	Participates in transcription elongation, termination and antitermination
H9L11_RS11150	COG0367	asparagine synthase
H9L11_RS11155	COG4651	solute:proton antiporter activity
H9L11_RS11155	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H9L11_RS11160	COG1846	Transcriptional regulator
H9L11_RS11160	COG1940	carbohydrate kinase activity
H9L11_RS11165	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
H9L11_RS11170	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9L11_RS11170	COG2190	(PTS) system
H9L11_RS11170	COG1263	PTS System
H9L11_RS11175	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
H9L11_RS11180	COG0735	belongs to the Fur family
H9L11_RS11190	COG0716	FMN binding
H9L11_RS11200	COG0596	Alpha beta hydrolase
H9L11_RS11205	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
H9L11_RS11210	COG0033	Phosphoglucomutase
H9L11_RS11220	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
H9L11_RS11235	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
H9L11_RS11240	COG1053	succinate dehydrogenase
H9L11_RS11245	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
H9L11_RS11250	COG0567	Dehydrogenase, E1 component
H9L11_RS11255	COG0508	dehydrogenase complex catalyzes the overall conversion of
H9L11_RS11260	COG0045	succinate-CoA ligase (ADP-forming) activity
H9L11_RS11270	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H9L11_RS11275	COG1121	(ABC) transporter
H9L11_RS11280	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
H9L11_RS11285	COG4977	sequence-specific DNA binding
H9L11_RS11290	COG1918	ferrous iron import across plasma membrane
H9L11_RS11315	COG0018	arginyl-trna synthetase
H9L11_RS11320	COG3102	Protein conserved in bacteria
H9L11_RS11325	COG0788	formyltetrahydrofolate deformylase activity
H9L11_RS11330	COG1199	ATP-dependent helicase activity
H9L11_RS11335	COG1214	PFAM Peptidase M22, glycoprotease
H9L11_RS11345	COG3065	identical protein binding
H9L11_RS11350	COG2267	carboxylic ester hydrolase activity
H9L11_RS11355	COG0318	PFAM AMP-dependent synthetase and ligase
H9L11_RS11360	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
H9L11_RS11365	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
H9L11_RS11370	COG2894	cell division
H9L11_RS11375	COG0850	regulation of cytokinetic process
H9L11_RS11380	COG3100	YcgL domain-containing protein
H9L11_RS11385	COG2951	lytic endotransglycosylase activity
H9L11_RS11395	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
H9L11_RS11400	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
H9L11_RS11410	COG2226	methyltransferase
H9L11_RS11420	COG1028	Short-chain dehydrogenase reductase Sdr
H9L11_RS11430	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
H9L11_RS11455	COG2986	histidine ammonia-lyase
H9L11_RS11460	COG1216	Glycosyl transferase, family 2
H9L11_RS11465	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
H9L11_RS11480	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H9L11_RS11485	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H9L11_RS11520	COG0513	Belongs to the DEAD box helicase family
H9L11_RS11525	COG0569	domain protein
H9L11_RS11530	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
H9L11_RS11545	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
H9L11_RS11550	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
H9L11_RS11555	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
H9L11_RS11560	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
H9L11_RS11575	COG0544	peptidyl-prolyl cis-trans isomerase activity
H9L11_RS11585	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
H9L11_RS11590	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
H9L11_RS11595	COG0776	regulation of translation
H9L11_RS11600	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H9L11_RS11605	COG1555	photosystem II stabilization
H9L11_RS11620	COG0232	Belongs to the dGTPase family. Type 2 subfamily
H9L11_RS11625	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
H9L11_RS11630	COG0436	Aminotransferase
H9L11_RS11635	COG1169	isochorismate synthase
H9L11_RS11640	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
H9L11_RS11650	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
H9L11_RS11670	COG2855	membrane
H9L11_RS11675	COG0477	Major facilitator Superfamily
H9L11_RS11720	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H9L11_RS11725	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H9L11_RS11740	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
H9L11_RS11745	COG1522	sequence-specific DNA binding
H9L11_RS11755	COG1946	Acyl-CoA thioesterase
H9L11_RS11760	COG3126	Type III secretion system lipoprotein chaperone (YscW)
H9L11_RS11785	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H9L11_RS11790	COG0516	GMP reductase activity
H9L11_RS11790	COG0517	IMP dehydrogenase activity
H9L11_RS11815	COG0537	adenosine 5'-monophosphoramidase activity
H9L11_RS11840	COG3150	esterase
H9L11_RS11845	COG1252	NADH dehydrogenase
H9L11_RS11860	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
H9L11_RS11870	COG4591	ABC-type transport system involved in lipoprotein release permease component
H9L11_RS11875	COG1136	(ABC) transporter
H9L11_RS11880	COG4591	ABC-type transport system involved in lipoprotein release permease component
H9L11_RS11890	COG0658	competence protein
H9L11_RS11890	COG2333	competence protein COMEC
H9L11_RS11905	COG1132	(ABC) transporter
H9L11_RS11925	COG2719	SpoVR family
H9L11_RS11930	COG2718	Belongs to the UPF0229 family
H9L11_RS11935	COG2766	serine protein kinase
H9L11_RS11940	COG3013	Belongs to the UPF0304 family
H9L11_RS11950	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
H9L11_RS11960	COG1882	Formate acetyltransferase
H9L11_RS12000	COG0708	Exodeoxyribonuclease III
H9L11_RS12010	COG3923	Primosomal replication protein n
H9L11_RS12015	COG0730	response to heat
H9L11_RS12020	COG1199	ATP-dependent helicase activity
H9L11_RS12025	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
H9L11_RS12030	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
H9L11_RS12035	COG1187	pseudouridine synthase activity
H9L11_RS12045	COG1278	Cold shock
H9L11_RS12050	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
H9L11_RS12055	COG0542	response to heat
H9L11_RS12060	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
H9L11_RS12065	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
H9L11_RS12070	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
H9L11_RS12090	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
H9L11_RS12095	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
H9L11_RS12100	COG0297	glycogen (starch) synthase activity
H9L11_RS12120	COG3070	regulator of competence-specific genes
H9L11_RS12125	COG1609	Transcriptional regulator
H9L11_RS12130	COG3381	protein complex oligomerization
H9L11_RS12135	COG0745	RESPONSE REGULATOR receiver
H9L11_RS12140	COG1434	Gram-negative-bacterium-type cell wall biogenesis
H9L11_RS12145	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
H9L11_RS12155	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
H9L11_RS12160	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
H9L11_RS12180	COG4067	protein conserved in archaea
H9L11_RS12180	COG0189	ligase activity
H9L11_RS12185	COG0500	methyltransferase
H9L11_RS12195	COG1801	Protein of unknown function DUF72
H9L11_RS12205	COG0217	transcriptional regulatory protein
H9L11_RS12210	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
H9L11_RS12215	COG0632	four-way junction helicase activity
H9L11_RS12220	COG2255	four-way junction helicase activity
H9L11_RS12225	COG1271	oxidase subunit
H9L11_RS12230	COG1294	oxidase, subunit
H9L11_RS12235	COG4890	Cyd operon protein YbgT
H9L11_RS12245	COG0824	Thioesterase
H9L11_RS12250	COG0811	peptide transport
H9L11_RS12265	COG0823	Involved in the tonB-independent uptake of proteins
H9L11_RS12270	COG2885	chlorophyll binding
H9L11_RS12275	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
H9L11_RS12280	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
H9L11_RS12290	COG3766	membrane
H9L11_RS12300	COG0754	glutathionylspermidine amidase activity
H9L11_RS12310	COG5002	protein histidine kinase activity
H9L11_RS12310	COG0784	Response regulator, receiver
H9L11_RS12355	COG1192	Involved in chromosome partitioning
H9L11_RS12360	COG1294	oxidase, subunit
H9L11_RS12365	COG1271	oxidase subunit
H9L11_RS12380	COG0840	transmembrane signaling receptor activity
H9L11_RS12385	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H9L11_RS12390	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H9L11_RS12415	COG3568	Endonuclease Exonuclease Phosphatase
H9L11_RS12440	COG0583	DNA-binding transcription factor activity
H9L11_RS12450	COG0686	Belongs to the AlaDH PNT family
H9L11_RS12460	COG1674	ftsk spoiiie
H9L11_RS12470	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
H9L11_RS12490	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
H9L11_RS12495	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
H9L11_RS12515	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
H9L11_RS12535	COG0300	oxidoreductase activity
H9L11_RS12550	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
H9L11_RS12560	COG2268	Band 7 protein
H9L11_RS12570	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
H9L11_RS12575	COG2915	High frequency lysogenization protein hflD homolog
H9L11_RS12590	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H9L11_RS12600	COG1757	Na H antiporter
H9L11_RS12610	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
H9L11_RS12620	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
H9L11_RS12620	COG0131	Imidazoleglycerol-phosphate dehydratase
H9L11_RS12625	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
H9L11_RS12630	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
H9L11_RS12640	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
H9L11_RS12640	COG0140	phosphoribosyl-ATP diphosphatase activity
H9L11_RS12645	COG3012	SEC-C Motif Domain Protein
H9L11_RS12650	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
H9L11_RS12655	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H9L11_RS12660	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
H9L11_RS12665	COG0215	cysteine-tRNA ligase activity
H9L11_RS12670	COG1435	thymidine kinase activity
H9L11_RS12700	COG2116	formate transmembrane transporter activity
H9L11_RS12710	COG0390	transport system, permease component
H9L11_RS12715	COG4459	periplasmic nitrate reductase
H9L11_RS12720	COG3005	denitrification pathway
H9L11_RS12725	COG0243	molybdopterin cofactor binding
H9L11_RS12740	COG1227	inorganic diphosphatase activity
H9L11_RS12750	COG4172	Belongs to the ABC transporter superfamily
H9L11_RS12760	COG4171	peptide transport system, permease
H9L11_RS12775	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
H9L11_RS12780	COG1842	Phage shock protein A
H9L11_RS12790	COG1983	PspC domain protein
H9L11_RS12810	COG2818	Glycosylase
H9L11_RS12815	COG5380	lipid catabolic process
H9L11_RS12820	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
H9L11_RS12825	COG0626	cystathionine gamma-synthase activity
H9L11_RS12835	COG0733	neurotransmitter:sodium symporter activity
H9L11_RS12840	COG0564	pseudouridine synthase activity
H9L11_RS12850	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H9L11_RS12855	COG1151	hydroxylamine reductase activity
H9L11_RS12860	COG3604	Transcriptional regulator
H9L11_RS12870	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
H9L11_RS12875	COG4136	ATPase activity
H9L11_RS12880	COG4135	transport system, permease component
H9L11_RS12885	COG4134	Bacterial extracellular solute-binding protein
H9L11_RS12895	COG3313	Fe-S protein
H9L11_RS12915	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
H9L11_RS12935	COG1061	Type III restriction enzyme res subunit
H9L11_RS12940	COG1187	pseudouridine synthase activity
H9L11_RS12945	COG2814	Major facilitator Superfamily
H9L11_RS12955	COG0702	epimerase
H9L11_RS12960	COG0534	Mate efflux family protein
H9L11_RS12980	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
H9L11_RS12990	COG1960	acyl-CoA dehydrogenase activity
H9L11_RS12995	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
H9L11_RS13000	COG2985	domain, Protein
H9L11_RS13000	COG3273	potassium ion transport
H9L11_RS13005	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
H9L11_RS13015	COG1737	Transcriptional regulator
H9L11_RS13020	COG0076	glutamate decarboxylase activity
H9L11_RS13030	COG2431	L-lysine efflux transmembrane transporter activity
H9L11_RS13040	COG3070	regulator of competence-specific genes
H9L11_RS13055	COG4191	Histidine kinase
H9L11_RS13055	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H9L11_RS13065	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
H9L11_RS13075	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
H9L11_RS13080	COG4988	ABC transporter
H9L11_RS13085	COG0492	ferredoxin-NADP+ reductase activity
H9L11_RS13110	COG0471	metal ion transport
H9L11_RS13115	COG2949	membrane
H9L11_RS13120	COG0281	malic enzyme
H9L11_RS13125	COG1643	Atp-dependent helicase
H9L11_RS13140	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
H9L11_RS13175	COG0277	FAD linked oxidase domain protein
H9L11_RS13175	COG0247	lactate metabolic process
H9L11_RS13190	COG2986	histidine ammonia-lyase
H9L11_RS13195	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
H9L11_RS13200	COG0010	Belongs to the arginase family
H9L11_RS13205	COG1228	amidohydrolase
H9L11_RS13210	COG2188	Transcriptional regulator
H9L11_RS13225	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
H9L11_RS13235	COG0291	Belongs to the bacterial ribosomal protein bL35 family
H9L11_RS13245	COG0393	Putative heavy-metal-binding
H9L11_RS13255	COG3335	DDE superfamily endonuclease
H9L11_RS13290	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
H9L11_RS13295	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H9L11_RS13295	COG0072	phenylalanine-tRNA ligase activity
H9L11_RS13305	COG0776	regulation of translation
H9L11_RS13315	COG0500	methyltransferase
H9L11_RS13320	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
H9L11_RS13325	COG0295	cytidine deaminase activity
H9L11_RS13330	COG1346	cytolysis
H9L11_RS13335	COG1380	Effector of murein hydrolase LrgA
H9L11_RS13340	COG2925	Exonuclease
H9L11_RS13345	COG1823	symporter activity
H9L11_RS13350	COG0702	epimerase
H9L11_RS13355	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
H9L11_RS13360	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
H9L11_RS13380	COG2988	succinylglutamate desuccinylase activity
H9L11_RS13385	COG4139	cobalamin transport
H9L11_RS13390	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
H9L11_RS13410	COG0583	DNA-binding transcription factor activity
H9L11_RS13420	COG1451	nucleotide metabolic process
H9L11_RS13425	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
H9L11_RS13455	COG3938	Belongs to the proline racemase family
H9L11_RS13470	COG2423	ornithine cyclodeaminase activity
H9L11_RS13475	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H9L11_RS13480	COG3842	ATPase activity
H9L11_RS13485	COG1176	ABC-type spermidine putrescine transport system, permease component I
H9L11_RS13490	COG1177	transmembrane transport
H9L11_RS13500	COG3291	Pkd domain containing protein
H9L11_RS13515	COG0444	Belongs to the ABC transporter superfamily
H9L11_RS13520	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H9L11_RS13525	COG0601	transmembrane transport
H9L11_RS13535	COG2195	Cleaves the N-terminal amino acid of tripeptides
H9L11_RS13545	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
H9L11_RS13555	COG0625	glutathione transferase activity
H9L11_RS13605	COG3755	Protein conserved in bacteria
H9L11_RS13630	COG1742	UPF0060 membrane protein
H9L11_RS13645	COG1757	Na H antiporter
H9L11_RS13650	COG0174	glutamine synthetase
H9L11_RS13655	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
H9L11_RS13660	COG1396	sequence-specific DNA binding
H9L11_RS13660	COG1917	Cupin 2, conserved barrel domain protein
H9L11_RS13665	COG1012	belongs to the aldehyde dehydrogenase family
H9L11_RS13670	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H9L11_RS13680	COG2957	Belongs to the agmatine deiminase family
H9L11_RS13685	COG1012	belongs to the aldehyde dehydrogenase family
H9L11_RS13690	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H9L11_RS13695	COG2200	EAL domain
H9L11_RS13705	COG1846	Transcriptional regulator
H9L11_RS13710	COG2315	Protein conserved in bacteria
H9L11_RS13750	COG3063	Type IV pilus biogenesis stability protein PilW
H9L11_RS13755	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
H9L11_RS13770	COG1560	Kdo2-lipid A biosynthetic process
H9L11_RS13780	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
H9L11_RS13895	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
H9L11_RS13900	COG1280	lysine exporter protein (LysE YggA)
H9L11_RS13910	COG1115	amino acid carrier protein
H9L11_RS13935	COG1368	sulfuric ester hydrolase activity
H9L11_RS13940	COG2113	Glycine betaine
H9L11_RS13945	COG4176	ABC-type proline glycine betaine transport system permease component
H9L11_RS13965	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H9L11_RS13970	COG0456	acetyltransferase
H9L11_RS13975	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H9L11_RS13980	COG0662	Cupin 2, conserved barrel domain protein
H9L11_RS13985	COG0527	aspartate kinase activity
H9L11_RS13990	COG3119	arylsulfatase activity
H9L11_RS14005	COG0641	radical SAM
H9L11_RS14020	COG3119	arylsulfatase activity
H9L11_RS14045	COG1538	Outer membrane efflux protein
H9L11_RS14060	COG1349	DNA-binding transcription factor activity
H9L11_RS14065	COG0673	inositol 2-dehydrogenase activity
H9L11_RS14070	COG4702	Belongs to the UPF0303 family
H9L11_RS14095	COG0471	metal ion transport
H9L11_RS14110	COG3300	MHYT domain
H9L11_RS14110	COG5001	Diguanylate cyclase
H9L11_RS14125	COG1328	CTP reductase activity
H9L11_RS14130	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
H9L11_RS14140	COG0861	Integral membrane protein TerC family
H9L11_RS14150	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
H9L11_RS14160	COG0814	amino acid
H9L11_RS14175	COG1120	ATPase activity
H9L11_RS14180	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H9L11_RS14190	COG4774	siderophore transport
H9L11_RS14200	COG1132	(ABC) transporter
H9L11_RS14205	COG1132	(ABC) transporter
H9L11_RS14210	COG2165	general secretion pathway protein
H9L11_RS14220	COG0583	DNA-binding transcription factor activity
H9L11_RS14245	COG0443	Heat shock 70 kDa protein
H9L11_RS14250	COG0443	Heat shock 70 kDa protein
H9L11_RS14295	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
H9L11_RS14300	COG1643	Atp-dependent helicase
H9L11_RS14315	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H9L11_RS14325	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
H9L11_RS14330	COG1215	transferase activity, transferring glycosyl groups
H9L11_RS14335	COG0438	transferase activity, transferring glycosyl groups
H9L11_RS14365	COG0438	transferase activity, transferring glycosyl groups
H9L11_RS14375	COG2204	response regulator
H9L11_RS14405	COG1793	dna ligase
H9L11_RS14415	COG0534	Mate efflux family protein
H9L11_RS14420	COG0307	riboflavin synthase, alpha
H9L11_RS14430	COG3001	Fructosamine kinase
H9L11_RS14440	COG3706	GGDEF domain
H9L11_RS14450	COG0791	NLP P60 protein
H9L11_RS14480	COG3148	PFAM DTW domain containing protein
H9L11_RS14485	COG1940	carbohydrate kinase activity
H9L11_RS14495	COG0303	'Molybdopterin
H9L11_RS14500	COG0746	molybdenum cofactor guanylyltransferase activity
H9L11_RS14505	COG3842	ATPase activity
H9L11_RS14520	COG2204	response regulator
H9L11_RS14525	COG3852	Histidine kinase
H9L11_RS14530	COG0488	(ABC) transporter
H9L11_RS14535	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
H9L11_RS14555	COG3381	protein complex oligomerization
H9L11_RS14565	COG3383	formate dehydrogenase (NAD+) activity
H9L11_RS14565	COG0243	molybdopterin cofactor binding
H9L11_RS14570	COG0437	4 iron, 4 sulfur cluster binding
H9L11_RS14675	COG4282	regulation of fungal-type cell wall biogenesis
H9L11_RS14705	COG0004	ammonium transporteR
H9L11_RS14715	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
H9L11_RS14745	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
H9L11_RS14755	COG1177	transmembrane transport
H9L11_RS14765	COG3842	ATPase activity
H9L11_RS14790	COG0589	response to stress
H9L11_RS14795	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H9L11_RS14810	COG2217	Heavy metal translocating P-type atpase
H9L11_RS14820	COG2010	Cytochrome c
H9L11_RS14835	COG3278	Belongs to the heme-copper respiratory oxidase family
H9L11_RS14995	COG3120	sequence-specific DNA binding
H9L11_RS15000	COG1067	ATP-dependent peptidase activity
H9L11_RS15005	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
H9L11_RS15020	COG0488	(ABC) transporter
H9L11_RS15030	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
H9L11_RS15030	COG0116	Belongs to the methyltransferase superfamily
H9L11_RS15040	COG0167	dihydroorotate dehydrogenase activity
H9L11_RS15045	COG2902	Dehydrogenase
H9L11_RS15055	COG0308	aminopeptidase N
H9L11_RS15070	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
H9L11_RS15075	COG1956	GAF domain-containing protein
H9L11_RS15080	COG1132	(ABC) transporter
H9L11_RS15085	COG2995	paraquat-inducible protein a
H9L11_RS15090	COG3008	intermembrane lipid transfer
H9L11_RS15115	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
H9L11_RS15120	COG1666	GTP binding
H9L11_RS15130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H9L11_RS15135	COG4597	amino acid ABC transporter
H9L11_RS15140	COG0765	amino acid transport
H9L11_RS15145	COG1126	abc transporter atp-binding protein
H9L11_RS15150	COG0670	Belongs to the BI1 family
H9L11_RS15160	COG2920	part of a sulfur-relay system
H9L11_RS15165	COG1254	Belongs to the acylphosphatase family
H9L11_RS15170	COG0840	transmembrane signaling receptor activity
H9L11_RS15195	COG2885	chlorophyll binding
H9L11_RS15220	COG2203	Gaf domain
H9L11_RS15220	COG2199	diguanylate cyclase activity
H9L11_RS15225	COG1414	Transcriptional regulator
H9L11_RS15235	COG0656	L-ascorbic acid biosynthetic process
H9L11_RS15240	COG0583	DNA-binding transcription factor activity
H9L11_RS15250	COG0583	DNA-binding transcription factor activity
H9L11_RS15255	COG2814	Major facilitator Superfamily
H9L11_RS15275	COG1335	isochorismatase
H9L11_RS15280	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H9L11_RS15295	COG0646	methionine synthase
H9L11_RS15295	COG1410	methionine synthase
H9L11_RS15300	COG1126	abc transporter atp-binding protein
H9L11_RS15305	COG0765	amino acid transport
H9L11_RS15310	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H9L11_RS15325	COG0583	DNA-binding transcription factor activity
H9L11_RS15340	COG0583	DNA-binding transcription factor activity
H9L11_RS15345	COG0583	DNA-binding transcription factor activity
H9L11_RS15360	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
H9L11_RS15365	COG0602	queuosine metabolic process
H9L11_RS15370	COG0561	phosphatase activity
H9L11_RS15395	COG2828	Protein conserved in bacteria
H9L11_RS15405	COG0372	Belongs to the citrate synthase family
H9L11_RS15410	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
H9L11_RS15445	COG0730	response to heat
H9L11_RS15450	COG2358	TRAP transporter, solute receptor (TAXI family
H9L11_RS15455	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
H9L11_RS15460	COG0252	asparaginase activity
H9L11_RS15465	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
H9L11_RS15480	COG2197	response regulator
H9L11_RS15485	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
H9L11_RS15505	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H9L11_RS15530	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H9L11_RS15560	COG3842	ATPase activity
H9L11_RS15580	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H9L11_RS15610	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H9L11_RS15645	COG0583	DNA-binding transcription factor activity
H9L11_RS15655	COG4948	Mandelate Racemase Muconate Lactonizing
H9L11_RS15685	COG1342	Belongs to the UPF0251 family
H9L11_RS15690	COG4176	ABC-type proline glycine betaine transport system permease component
H9L11_RS15695	COG4175	Glycine betaine
H9L11_RS15695	COG3448	diguanylate cyclase activity
H9L11_RS15700	COG3015	lipoprotein NlpE involved in copper resistance
H9L11_RS15705	COG3713	MltA-interacting MipA family protein
H9L11_RS15720	COG0583	DNA-binding transcription factor activity
H9L11_RS15745	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
H9L11_RS15755	COG1335	isochorismatase
H9L11_RS15770	COG1349	DNA-binding transcription factor activity
H9L11_RS15780	COG2070	2-Nitropropane dioxygenase
H9L11_RS15785	COG0531	amino acid
H9L11_RS15790	COG4302	ethanolamine ammonia-lyase activity
H9L11_RS15795	COG4303	Ethanolamine ammonia lyase large subunit
H9L11_RS15805	COG1309	transcriptional regulator
H9L11_RS15825	COG1280	lysine exporter protein (LysE YggA)
H9L11_RS15835	COG0459	protein refolding
H9L11_RS15840	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
H9L11_RS15845	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H9L11_RS15860	COG1304	FMN binding
H9L11_RS15885	COG1256	bacterial-type flagellum assembly
H9L11_RS15885	COG4786	Flagellar basal body rod
H9L11_RS15895	COG1706	bacterial-type flagellum-dependent cell motility
H9L11_RS15900	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
H9L11_RS15905	COG4786	Flagellar basal body rod
H9L11_RS15910	COG4787	bacterial-type flagellum-dependent cell motility
H9L11_RS15925	COG1558	bacterial-type flagellum-dependent cell motility
H9L11_RS15930	COG1815	bacterial-type flagellum-dependent cell motility
H9L11_RS15950	COG1388	LysM domain
H9L11_RS15950	COG0741	lytic transglycosylase activity
H9L11_RS15955	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
H9L11_RS15975	COG1760	l-serine dehydratase
H9L11_RS15990	COG0583	DNA-binding transcription factor activity
H9L11_RS16000	COG2866	Carboxypeptidase
H9L11_RS16005	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H9L11_RS16015	COG2990	Protein conserved in bacteria
H9L11_RS16040	COG3842	ATPase activity
H9L11_RS16045	COG1840	ABC-type Fe3 transport system, periplasmic component
H9L11_RS16055	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H9L11_RS16065	COG1609	Transcriptional regulator
H9L11_RS16095	COG3240	lipase activity
H9L11_RS16100	COG1309	transcriptional regulator
H9L11_RS16115	COG1136	(ABC) transporter
H9L11_RS16115	COG0577	efflux transmembrane transporter activity
H9L11_RS16120	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H9L11_RS16125	COG2067	long-chain fatty acid transport protein
H9L11_RS16135	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
H9L11_RS16150	COG1011	Hydrolase
H9L11_RS16185	COG0110	maltose O-acetyltransferase activity
H9L11_RS16190	COG1765	OsmC-like protein
H9L11_RS16195	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
H9L11_RS16195	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
H9L11_RS16210	COG3046	protein related to deoxyribodipyrimidine photolyase
H9L11_RS16215	COG0415	Belongs to the DNA photolyase family
H9L11_RS16220	COG3706	GGDEF domain
H9L11_RS16235	COG3706	GGDEF domain
H9L11_RS16250	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
H9L11_RS16270	COG3033	Beta-eliminating lyase
H9L11_RS16280	COG1271	oxidase subunit
H9L11_RS16285	COG1294	oxidase, subunit
H9L11_RS16305	COG0579	oxidoreductase
H9L11_RS16325	COG3706	GGDEF domain
H9L11_RS16335	COG4191	Histidine kinase
H9L11_RS16355	COG0583	DNA-binding transcription factor activity
H9L11_RS16375	COG0189	ligase activity
H9L11_RS16380	COG0189	ligase activity
H9L11_RS16380	COG4067	protein conserved in archaea
H9L11_RS16390	COG1166	arginine decarboxylase activity
H9L11_RS16395	COG0010	Belongs to the arginase family
H9L11_RS16400	COG2814	Major facilitator Superfamily
H9L11_RS16405	COG1770	oligopeptidase
H9L11_RS16420	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H9L11_RS16425	COG1121	(ABC) transporter
H9L11_RS16430	COG0803	Belongs to the bacterial solute-binding protein 9 family
H9L11_RS16475	COG0848	biopolymer transport protein
H9L11_RS16480	COG0811	peptide transport
H9L11_RS16485	COG0811	peptide transport
H9L11_RS16505	COG0745	RESPONSE REGULATOR receiver
H9L11_RS16510	COG0584	glycerophosphoryl diester phosphodiesterase
H9L11_RS16520	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
H9L11_RS16665	COG0312	modulator of DNA gyrase
H9L11_RS16670	COG0312	modulator of DNA gyrase
H9L11_RS16675	COG0351	phosphomethylpyrimidine kinase
H9L11_RS16680	COG1116	anion transmembrane transporter activity
H9L11_RS16685	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H9L11_RS16690	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H9L11_RS16695	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
H9L11_RS16715	COG0243	molybdopterin cofactor binding
H9L11_RS16720	COG3005	denitrification pathway
H9L11_RS16725	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H9L11_RS16730	COG1028	Short-chain dehydrogenase reductase Sdr
H9L11_RS16745	COG0456	acetyltransferase
H9L11_RS16765	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H9L11_RS16770	COG1929	Belongs to the glycerate kinase type-1 family
H9L11_RS16775	COG2610	gluconate transmembrane transporter activity
H9L11_RS16780	COG3835	regulator
H9L11_RS16840	COG3047	cAMP biosynthetic process
H9L11_RS16845	COG1357	PFAM Pentapeptide repeats (8 copies)
H9L11_RS16875	COG2375	cellular response to nickel ion
H9L11_RS16880	COG0583	DNA-binding transcription factor activity
H9L11_RS16885	COG2162	N-hydroxyarylamine O-acetyltransferase activity
H9L11_RS16890	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
H9L11_RS16905	COG2199	diguanylate cyclase activity
H9L11_RS16915	COG0561	phosphatase activity
H9L11_RS16920	COG0583	DNA-binding transcription factor activity
H9L11_RS16935	COG0564	pseudouridine synthase activity
H9L11_RS16940	COG0534	Mate efflux family protein
H9L11_RS16955	COG3123	guanosine phosphorylase activity
H9L11_RS16970	COG0596	Alpha beta hydrolase
H9L11_RS16995	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H9L11_RS17005	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H9L11_RS17010	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H9L11_RS17010	COG2169	Transcriptional regulator
H9L11_RS17020	COG2259	Doxx family
H9L11_RS17025	COG1741	Belongs to the pirin family
H9L11_RS17045	COG0363	glucosamine-6-phosphate deaminase activity
H9L11_RS17055	COG0786	glutamate:sodium symporter activity
H9L11_RS17060	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H9L11_RS17065	COG1131	(ABC) transporter
H9L11_RS17075	COG0786	glutamate:sodium symporter activity
H9L11_RS17095	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
H9L11_RS17105	COG3279	Response regulator of the LytR AlgR family
H9L11_RS17110	COG3275	phosphorelay sensor kinase activity
H9L11_RS17140	COG0772	Belongs to the SEDS family
H9L11_RS17165	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
H9L11_RS17165	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
H9L11_RS17175	COG0444	Belongs to the ABC transporter superfamily
H9L11_RS17180	COG4608	Belongs to the ABC transporter superfamily
H9L11_RS17205	COG1444	tRNA N-acetyltransferase activity
H9L11_RS17225	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
H9L11_RS17230	COG1263	PTS System
H9L11_RS17230	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9L11_RS17235	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
H9L11_RS17250	COG4166	transmembrane transport
H9L11_RS17305	COG0259	pyridoxamine-phosphate oxidase activity
H9L11_RS17330	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H9L11_RS17365	COG1132	(ABC) transporter
H9L11_RS17375	COG0513	Belongs to the DEAD box helicase family
H9L11_RS17380	COG2258	MOSC domain
H9L11_RS17425	COG3634	alkyl hydroperoxide reductase activity
H9L11_RS17435	COG1846	Transcriptional regulator
H9L11_RS17440	COG1764	response to oxidative stress
H9L11_RS17475	COG0577	efflux transmembrane transporter activity
H9L11_RS17480	COG1136	(ABC) transporter
H9L11_RS17490	COG0826	peptidase U32
H9L11_RS17515	COG1653	transport
H9L11_RS17520	COG0019	diaminopimelate decarboxylase activity
H9L11_RS17525	COG4264	IucA IucC family
H9L11_RS17550	COG4772	TonB-dependent receptor
H9L11_RS17555	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
H9L11_RS17560	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H9L11_RS17565	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H9L11_RS17570	COG1120	ATPase activity
H9L11_RS17575	COG0840	transmembrane signaling receptor activity
H9L11_RS17580	COG0612	Peptidase, M16
H9L11_RS17590	COG0739	heme binding
H9L11_RS17605	COG2814	Major facilitator Superfamily
H9L11_RS17615	COG1609	Transcriptional regulator
H9L11_RS17620	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H9L11_RS17635	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
H9L11_RS17635	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
H9L11_RS17640	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
H9L11_RS17640	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
H9L11_RS17645	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
H9L11_RS17650	COG1609	Transcriptional regulator
H9L11_RS17660	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
H9L11_RS17700	COG1760	l-serine dehydratase
H9L11_RS17710	COG4580	involved in the transport of maltose and maltodextrins
H9L11_RS17730	COG2356	endonuclease I
H9L11_RS17750	COG1982	Orn Lys Arg decarboxylase major
H9L11_RS17755	COG0531	amino acid
H9L11_RS17765	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
H9L11_RS17770	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
H9L11_RS17775	COG1162	GTPase activity
H9L11_RS17780	COG1263	PTS System
H9L11_RS17780	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9L11_RS17785	COG1999	signal sequence binding
H9L11_RS17800	COG2909	trisaccharide binding
H9L11_RS17805	COG0058	SHG alpha-glucan phosphorylase activity
H9L11_RS17810	COG1640	4-alpha-glucanotransferase
H9L11_RS17815	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
H9L11_RS17820	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H9L11_RS17825	COG0366	Alpha amylase catalytic
H9L11_RS17840	COG3366	ferrous iron transmembrane transporter activity
H9L11_RS17845	COG0700	Nucleoside recognition
H9L11_RS17850	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H9L11_RS17855	COG3339	Conserved Protein
H9L11_RS17870	COG1301	dicarboxylic acid transport
H9L11_RS17880	COG0583	DNA-binding transcription factor activity
H9L11_RS17895	COG0489	protein tyrosine kinase activity
H9L11_RS17895	COG3206	protein involved in exopolysaccharide biosynthesis
H9L11_RS17915	COG2095	MarC family integral membrane protein
H9L11_RS17920	COG4667	esterase of the alpha-beta hydrolase superfamily
H9L11_RS17925	COG3397	chitin binding
H9L11_RS17930	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
H9L11_RS17935	COG0415	Belongs to the DNA photolyase family
H9L11_RS17945	COG1054	Belongs to the UPF0176 family
H9L11_RS17955	COG1686	Belongs to the peptidase S11 family
H9L11_RS17980	COG0583	DNA-binding transcription factor activity
H9L11_RS17985	COG4628	conserved protein (DUF2132)
H9L11_RS18005	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
H9L11_RS18010	COG0628	permease
H9L11_RS18035	COG1289	transmembrane transporter activity
H9L11_RS18050	COG2814	Major facilitator Superfamily
H9L11_RS18060	COG0454	-acetyltransferase
H9L11_RS18070	COG0745	RESPONSE REGULATOR receiver
H9L11_RS18075	COG2205	protein histidine kinase activity
H9L11_RS18090	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
H9L11_RS18095	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
H9L11_RS18100	COG1882	Formate acetyltransferase
H9L11_RS18130	COG1360	Flagellar Motor Protein
H9L11_RS18135	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
H9L11_RS18140	COG1191	sigma factor activity
H9L11_RS18145	COG1580	Controls the rotational direction of flagella during chemotaxis
H9L11_RS18160	COG1516	flagellar protein fliS
H9L11_RS18165	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
H9L11_RS18175	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
H9L11_RS18190	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
H9L11_RS18200	COG1987	bacterial-type flagellum assembly
H9L11_RS18240	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
H9L11_RS18300	COG0346	lactoylglutathione lyase activity
H9L11_RS18325	COG0745	RESPONSE REGULATOR receiver
H9L11_RS18350	COG3300	MHYT domain
H9L11_RS18350	COG5001	Diguanylate cyclase
H9L11_RS18355	COG0156	8-amino-7-oxononanoate synthase activity
H9L11_RS18360	COG1063	alcohol dehydrogenase
H9L11_RS18395	COG0668	transmembrane transport
H9L11_RS18405	COG1304	FMN binding
H9L11_RS18410	COG1620	l-lactate permease
H9L11_RS18415	COG0583	DNA-binding transcription factor activity
H9L11_RS18420	COG1505	serine-type exopeptidase activity
H9L11_RS18425	COG4172	Belongs to the ABC transporter superfamily
H9L11_RS18435	COG1067	ATP-dependent peptidase activity
H9L11_RS18445	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
H9L11_RS18465	COG1247	-acetyltransferase
H9L11_RS18470	COG0437	4 iron, 4 sulfur cluster binding
H9L11_RS18475	COG0348	domain, Protein
H9L11_RS18495	COG1122	ATPase activity
H9L11_RS18500	COG4720	Psort location CytoplasmicMembrane, score
H9L11_RS18505	COG1566	PFAM secretion protein HlyD family protein
H9L11_RS18530	COG0813	purine-nucleoside phosphorylase activity
H9L11_RS18535	COG3272	Protein of unknown function (DUF1722)
H9L11_RS18540	COG0789	Transcriptional regulator
H9L11_RS18545	COG0415	Belongs to the DNA photolyase family
H9L11_RS18550	COG1388	LysM domain
H9L11_RS18550	COG1376	ErfK ybiS ycfS ynhG family protein
H9L11_RS18560	COG0513	Belongs to the DEAD box helicase family
H9L11_RS18565	COG1770	oligopeptidase
H9L11_RS18570	COG4771	TonB-dependent receptor
H9L11_RS18600	COG0573	inorganic phosphate transmembrane transporter activity
H9L11_RS18605	COG0581	inorganic phosphate transmembrane transporter activity
H9L11_RS18610	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
H9L11_RS18645	COG0714	Associated with various cellular activities
H9L11_RS18660	COG2197	response regulator
H9L11_RS18695	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
H9L11_RS18700	COG1120	ATPase activity
H9L11_RS18705	COG4774	siderophore transport
H9L11_RS18710	COG1132	(ABC) transporter
H9L11_RS18715	COG2205	protein histidine kinase activity
H9L11_RS18715	COG2205	protein histidine kinase activity
H9L11_RS18725	COG0569	domain protein
H9L11_RS18730	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
H9L11_RS18735	COG0583	DNA-binding transcription factor activity
H9L11_RS18740	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H9L11_RS18750	COG1012	belongs to the aldehyde dehydrogenase family
H9L11_RS18755	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H9L11_RS18760	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H9L11_RS18770	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
H9L11_RS18775	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H9L11_RS18805	COG2084	Dehydrogenase
H9L11_RS18810	COG0753	catalase activity
H9L11_RS18820	COG2130	NADP-dependent
H9L11_RS18825	COG1309	transcriptional regulator
H9L11_RS18830	COG3097	Belongs to the UPF0267 family
H9L11_RS18870	COG3206	protein involved in exopolysaccharide biosynthesis
H9L11_RS18870	COG0489	protein tyrosine kinase activity
H9L11_RS18885	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
H9L11_RS18890	COG3842	ATPase activity
H9L11_RS18900	COG1175	transmembrane transport
H9L11_RS18905	COG3833	ABC-type maltose transport systems, permease component
H9L11_RS18935	COG2375	cellular response to nickel ion
H9L11_RS18935	COG1132	(ABC) transporter
H9L11_RS18940	COG4774	siderophore transport
H9L11_RS18945	COG4607	ABC-type enterochelin transport system periplasmic component
H9L11_RS18950	COG4605	iron ion homeostasis
H9L11_RS18955	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H9L11_RS18965	COG2354	Protein conserved in bacteria
H9L11_RS18970	COG0418	dihydroorotase activity
H9L11_RS18975	COG0401	homolog of Blt101
H9L11_RS18980	COG3217	Mosc domain protein beta barrel domain protein
H9L11_RS18980	COG0633	Ferredoxin
H9L11_RS18980	COG3217	Mosc domain protein beta barrel domain protein
H9L11_RS18980	COG0633	Ferredoxin
H9L11_RS18990	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
H9L11_RS19030	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
H9L11_RS19035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H9L11_RS19045	COG0848	biopolymer transport protein
H9L11_RS19050	COG0811	peptide transport
H9L11_RS19055	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
H9L11_RS19065	COG3721	Heme iron utilization protein
H9L11_RS19070	COG0748	coenzyme F420 binding
H9L11_RS19080	COG0784	Response regulator, receiver
H9L11_RS19080	COG0835	chemotaxis
H9L11_RS19085	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H9L11_RS19090	COG0534	Mate efflux family protein
H9L11_RS19095	COG0444	Belongs to the ABC transporter superfamily
H9L11_RS19100	COG4608	Belongs to the ABC transporter superfamily
H9L11_RS19105	COG0747	negative chemotaxis
H9L11_RS19115	COG1349	DNA-binding transcription factor activity
H9L11_RS19120	COG2084	Dehydrogenase
H9L11_RS19125	COG3395	kinase activity
H9L11_RS19130	COG0235	Class ii aldolase
H9L11_RS19135	COG3622	Belongs to the hyi family
H9L11_RS19140	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H9L11_RS19145	COG2610	gluconate transmembrane transporter activity
H9L11_RS19165	COG0583	DNA-binding transcription factor activity
H9L11_RS19170	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
H9L11_RS19180	COG4934	collagen metabolic process
H9L11_RS19190	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H9L11_RS19195	COG0789	Transcriptional regulator
H9L11_RS19200	COG0366	Alpha amylase catalytic
H9L11_RS19220	COG2249	NAD(P)H dehydrogenase (quinone) activity
H9L11_RS19225	COG0589	response to stress
H9L11_RS19230	COG0488	(ABC) transporter
H9L11_RS19235	COG1505	serine-type exopeptidase activity
H9L11_RS19245	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H9L11_RS19255	COG2067	long-chain fatty acid transport protein
H9L11_RS19265	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H9L11_RS19290	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H9L11_RS19310	COG3383	formate dehydrogenase (NAD+) activity
H9L11_RS19320	COG0842	Transport permease protein
H9L11_RS19325	COG1131	(ABC) transporter
H9L11_RS19340	COG1881	PFAM PEBP family protein
H9L11_RS19350	COG0798	PFAM Bile acid sodium symporter
H9L11_RS19365	COG1733	regulation of RNA biosynthetic process
H9L11_RS19390	COG4989	oxidoreductase activity
H9L11_RS19415	COG0814	amino acid
H9L11_RS19430	COG3314	Sporulation integral membrane protein YlbJ
H9L11_RS19450	COG0739	heme binding
H9L11_RS19455	COG5001	Diguanylate cyclase
H9L11_RS19460	COG0583	DNA-binding transcription factor activity
H9L11_RS19465	COG2814	Major facilitator Superfamily
H9L11_RS19480	COG0697	spore germination
H9L11_RS19495	COG0179	Fumarylacetoacetate (FAA) hydrolase
H9L11_RS19515	COG1280	lysine exporter protein (LysE YggA)
H9L11_RS19525	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H9L11_RS19530	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
H9L11_RS19535	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
H9L11_RS19540	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
H9L11_RS19545	COG1845	cytochrome c oxidase, subunit III
H9L11_RS19565	COG1612	heme a metabolic process
H9L11_RS19570	COG0109	protoheme IX farnesyltransferase activity
H9L11_RS19575	COG0545	Peptidyl-prolyl cis-trans isomerase
H9L11_RS19605	COG1278	Cold shock
H9L11_RS19610	COG3036	rescue of stalled ribosome
H9L11_RS19615	COG2199	diguanylate cyclase activity
H9L11_RS19630	COG1132	(ABC) transporter
H9L11_RS19640	COG1538	Outer membrane efflux protein
H9L11_RS19645	COG0784	Response regulator, receiver
H9L11_RS19645	COG2205	protein histidine kinase activity
H9L11_RS19670	COG0840	transmembrane signaling receptor activity
H9L11_RS19675	COG0783	Belongs to the Dps family
H9L11_RS19685	COG2133	pyrroloquinoline quinone binding
H9L11_RS19690	COG1454	alcohol dehydrogenase
H9L11_RS19695	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
H9L11_RS19720	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
H9L11_RS19725	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H9L11_RS19730	COG3186	Phenylalanine-4-hydroxylase
H9L11_RS19755	COG3530	Putative quorum-sensing-regulated virulence factor
H9L11_RS19770	COG2814	Major facilitator Superfamily
H9L11_RS19775	COG0513	Belongs to the DEAD box helicase family
H9L11_RS19780	COG4628	conserved protein (DUF2132)
H9L11_RS19790	COG0133	tryptophan synthase activity
H9L11_RS19795	COG1278	Cold shock
H9L11_RS19805	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
H9L11_RS19815	COG0523	cobalamin synthesis protein
H9L11_RS19820	COG0513	Belongs to the DEAD box helicase family
H9L11_RS19840	COG2200	EAL domain
H9L11_RS19845	COG1119	ATPase activity
H9L11_RS19880	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
H9L11_RS19885	COG0513	Belongs to the DEAD box helicase family
H9L11_RS19895	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
H9L11_RS19905	COG1073	alpha beta
H9L11_RS19910	COG1073	alpha beta
H9L11_RS19925	COG0730	response to heat
H9L11_RS19940	COG0735	belongs to the Fur family
H9L11_RS19945	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
H9L11_RS19955	COG0523	cobalamin synthesis protein
H9L11_RS19965	COG0739	heme binding
H9L11_RS19970	COG0523	cobalamin synthesis protein
H9L11_RS19985	COG2095	MarC family integral membrane protein
H9L11_RS20015	COG1024	Enoyl-CoA hydratase
H9L11_RS20020	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
H9L11_RS20025	COG1960	acyl-CoA dehydrogenase activity
H9L11_RS20035	COG0183	Belongs to the thiolase family
H9L11_RS20050	COG1024	Enoyl-CoA hydratase
H9L11_RS20055	COG1024	Enoyl-CoA hydratase
H9L11_RS20065	COG1028	Short-chain dehydrogenase reductase Sdr
H9L11_RS20070	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
H9L11_RS20075	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
H9L11_RS20080	COG1845	cytochrome c oxidase, subunit III
H9L11_RS20085	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
H9L11_RS20090	COG0109	protoheme IX farnesyltransferase activity
H9L11_RS20095	COG0446	pyridine nucleotide-disulphide oxidoreductase
H9L11_RS20095	COG1902	pentaerythritol trinitrate reductase activity
H9L11_RS20110	COG1012	belongs to the aldehyde dehydrogenase family
H9L11_RS20120	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H9L11_RS20150	COG1126	abc transporter atp-binding protein
H9L11_RS20155	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H9L11_RS20160	COG4215	(ABC) transporter
H9L11_RS20165	COG4160	amino acid transport
H9L11_RS20235	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H9L11_RS20240	COG2176	DNA-directed DNA polymerase activity
H9L11_RS20245	COG0517	IMP dehydrogenase activity
H9L11_RS20250	COG2186	Transcriptional regulator
H9L11_RS20255	COG2186	Transcriptional regulator
H9L11_RS20300	COG1917	Cupin 2, conserved barrel domain protein
H9L11_RS20305	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H9L11_RS20310	COG0800	Aldolase
H9L11_RS20320	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
H9L11_RS20325	COG1028	Short-chain dehydrogenase reductase Sdr
H9L11_RS20330	COG2847	Copper chaperone PCu(A)C
H9L11_RS20400	COG0814	amino acid
H9L11_RS20410	COG0243	molybdopterin cofactor binding
H9L11_RS20435	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H9L11_RS20435	COG1116	anion transmembrane transporter activity
H9L11_RS20440	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H9L11_RS20445	COG1116	anion transmembrane transporter activity
H9L11_RS20450	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H9L11_RS20450	COG2146	nitrite reductase [NAD(P)H] activity
H9L11_RS20500	COG0515	serine threonine protein kinase
H9L11_RS20500	COG2815	serine threonine protein kinase
H9L11_RS20535	COG0631	protein serine/threonine phosphatase activity
H9L11_RS20605	COG0420	3'-5' exonuclease activity
H9L11_RS20610	COG0419	ATPase involved in DNA repair
H9L11_RS20620	COG3040	lipid binding
H9L11_RS20630	COG1288	antiporter activity
H9L11_RS20640	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
H9L11_RS20655	COG2425	protein containing a von Willebrand factor type A (vWA) domain
H9L11_RS20670	COG0583	DNA-binding transcription factor activity
H9L11_RS20675	COG0277	FAD linked oxidase domain protein
H9L11_RS20690	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
H9L11_RS20740	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H9L11_RS20760	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
H9L11_RS20765	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H9L11_RS20775	COG2116	formate transmembrane transporter activity
H9L11_RS20795	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
H9L11_RS20830	COG3118	belongs to the thioredoxin family
H9L11_RS20835	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
H9L11_RS20860	COG2271	Major facilitator Superfamily
H9L11_RS20865	COG3851	Histidine kinase
H9L11_RS20870	COG2197	response regulator
H9L11_RS20880	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
H9L11_RS20885	COG0583	DNA-binding transcription factor activity
H9L11_RS20890	COG0243	molybdopterin cofactor binding
H9L11_RS20905	COG0384	phenazine biosynthesis protein PhzF
H9L11_RS20910	COG1794	racemase activity, acting on amino acids and derivatives
H9L11_RS20940	COG1328	CTP reductase activity
H9L11_RS20945	COG0602	queuosine metabolic process
H9L11_RS20950	COG0534	Mate efflux family protein
H9L11_RS20955	COG2207	Transcriptional regulator
H9L11_RS20965	COG0189	ligase activity
H9L11_RS20965	COG4067	protein conserved in archaea
H9L11_RS20975	COG3111	PFAM Bacterial OB fold (BOF) protein
H9L11_RS20985	COG0725	ABC transporter, periplasmic molybdate-binding protein
H9L11_RS20990	COG4149	molybdate abc transporter
H9L11_RS20995	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
H9L11_RS21005	COG2203	Gaf domain
H9L11_RS21005	COG5001	Diguanylate cyclase
H9L11_RS21005	COG4251	negative regulation of phosphorylation
H9L11_RS21005	COG3706	GGDEF domain
H9L11_RS21025	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
H9L11_RS21030	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
H9L11_RS21055	COG3140	Belongs to the UPF0181 family
H9L11_RS21070	COG0583	DNA-binding transcription factor activity
H9L11_RS21085	COG0023	Translation Initiation Factor
H9L11_RS21095	COG1181	Belongs to the D-alanine--D-alanine ligase family
H9L11_RS21105	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H9L11_RS21105	COG0045	succinate-CoA ligase (ADP-forming) activity
H9L11_RS21105	COG1042	CoA-binding domain protein
H9L11_RS21110	COG0583	DNA-binding transcription factor activity
H9L11_RS21125	COG5002	protein histidine kinase activity
H9L11_RS21125	COG5001	Diguanylate cyclase
H9L11_RS21125	COG3447	MASE1 domain protein
H9L11_RS21130	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
H9L11_RS21135	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
H9L11_RS21140	COG1984	allophanate hydrolase subunit 2
H9L11_RS21150	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
H9L11_RS21155	COG4181	ATPase activity
H9L11_RS21165	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
H9L11_RS21170	COG3300	MHYT domain
H9L11_RS21170	COG5001	Diguanylate cyclase
H9L11_RS21205	COG4533	DNA binding
H9L11_RS21215	COG2050	protein possibly involved in aromatic compounds catabolism
H9L11_RS21230	COG2067	long-chain fatty acid transport protein
H9L11_RS21235	COG2267	carboxylic ester hydrolase activity
H9L11_RS21260	COG0737	Belongs to the 5'-nucleotidase family
H9L11_RS21265	COG3593	DNA synthesis involved in DNA repair
H9L11_RS21275	COG0583	DNA-binding transcription factor activity
H9L11_RS21280	COG2116	formate transmembrane transporter activity
H9L11_RS21285	COG2353	YceI-like domain
H9L11_RS21290	COG3038	cytochrome b561
H9L11_RS21310	COG0513	Belongs to the DEAD box helicase family
H9L11_RS21315	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
H9L11_RS21325	COG0840	transmembrane signaling receptor activity
H9L11_RS21330	COG0546	phosphoglycolate phosphatase activity
H9L11_RS21345	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H9L11_RS21350	COG2759	Belongs to the formate--tetrahydrofolate ligase family
H9L11_RS21355	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
H9L11_RS21365	COG2207	Transcriptional regulator
H9L11_RS21370	COG1979	alcohol dehydrogenase
H9L11_RS21380	COG1126	abc transporter atp-binding protein
H9L11_RS21385	COG0765	amino acid transport
H9L11_RS21390	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H9L11_RS21395	COG0765	amino acid transport
H9L11_RS21415	COG1609	Transcriptional regulator
H9L11_RS21420	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H9L11_RS21420	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
H9L11_RS21425	COG1105	Belongs to the carbohydrate kinase PfkB family
H9L11_RS21430	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
H9L11_RS21430	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H9L11_RS21430	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H9L11_RS21460	COG0404	The glycine cleavage system catalyzes the degradation of glycine
H9L11_RS21470	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
H9L11_RS21475	COG0509	glycine decarboxylation via glycine cleavage system
H9L11_RS21485	COG0346	lactoylglutathione lyase activity
H9L11_RS21490	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H9L11_RS21495	COG0583	DNA-binding transcription factor activity
H9L11_RS21500	COG0697	spore germination
H9L11_RS21505	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H9L11_RS21560	COG2176	DNA-directed DNA polymerase activity
H9L11_RS21605	COG0242	peptide deformylase activity
H9L11_RS21635	COG2239	Acts as a magnesium transporter
H9L11_RS21655	COG0346	lactoylglutathione lyase activity
H9L11_RS21660	COG1902	pentaerythritol trinitrate reductase activity
H9L11_RS21670	COG2755	lipolytic protein G-D-S-L family
H9L11_RS21670	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
H9L11_RS21680	COG5642	Protein of unknown function (DUF2384)
H9L11_RS21685	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
H9L11_RS21720	COG2076	Multidrug Resistance protein
H9L11_RS21740	COG2962	Rard protein
H9L11_RS21755	COG0784	Response regulator, receiver
H9L11_RS21755	COG0835	chemotaxis
H9L11_RS21760	COG2197	response regulator
H9L11_RS21770	COG3706	GGDEF domain
H9L11_RS21775	COG2197	response regulator
H9L11_RS21780	COG5001	Diguanylate cyclase
H9L11_RS21780	COG3300	MHYT domain
H9L11_RS21790	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
H9L11_RS21810	COG0456	acetyltransferase
H9L11_RS21810	COG1214	PFAM Peptidase M22, glycoprotease
H9L11_RS21820	COG3069	C4-dicarboxylate transmembrane transporter activity
H9L11_RS21845	COG3111	PFAM Bacterial OB fold (BOF) protein
H9L11_RS21850	COG1597	lipid kinase activity
H9L11_RS21855	COG0583	DNA-binding transcription factor activity
H9L11_RS21860	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H9L11_RS21890	COG0714	Associated with various cellular activities
H9L11_RS21895	COG0641	radical SAM
H9L11_RS21900	COG3119	arylsulfatase activity
H9L11_RS21910	COG3119	arylsulfatase activity
H9L11_RS21915	COG0745	RESPONSE REGULATOR receiver
H9L11_RS21930	COG0784	Response regulator, receiver
H9L11_RS21930	COG2198	Histidine kinase
H9L11_RS21930	COG2205	protein histidine kinase activity
H9L11_RS21935	COG1879	ABC-type sugar transport system periplasmic component
H9L11_RS21940	COG1803	Methylglyoxal synthase
H9L11_RS21945	COG0210	DNA helicase
H9L11_RS21950	COG1289	transmembrane transporter activity
H9L11_RS21980	COG1629	transport
H9L11_RS21980	COG4771	TonB-dependent receptor
H9L11_RS21985	COG2207	Transcriptional regulator
H9L11_RS21990	COG0789	Transcriptional regulator
H9L11_RS21995	COG4604	ABC transporter, ATP-binding protein
H9L11_RS22000	COG4605	iron ion homeostasis
H9L11_RS22005	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H9L11_RS22010	COG4607	ABC-type enterochelin transport system periplasmic component
H9L11_RS22020	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
H9L11_RS22035	COG1609	Transcriptional regulator
H9L11_RS22040	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H9L11_RS22045	COG1879	ABC-type sugar transport system periplasmic component
H9L11_RS22050	COG1172	Belongs to the binding-protein-dependent transport system permease family
H9L11_RS22055	COG1129	ABC transporter
H9L11_RS22060	COG1869	D-ribose catabolic process
H9L11_RS22065	COG5001	Diguanylate cyclase
H9L11_RS22120	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H9L11_RS22130	COG2205	protein histidine kinase activity
H9L11_RS22130	COG0784	Response regulator, receiver
H9L11_RS22140	COG3335	DDE superfamily endonuclease
H9L11_RS22150	COG0330	HflC and HflK could
H9L11_RS22165	COG4175	Glycine betaine
H9L11_RS22165	COG0517	IMP dehydrogenase activity
H9L11_RS22170	COG4176	ABC-type proline glycine betaine transport system permease component
H9L11_RS22185	COG1012	belongs to the aldehyde dehydrogenase family
H9L11_RS22190	COG1309	transcriptional regulator
H9L11_RS22200	COG1028	Short-chain dehydrogenase reductase Sdr
H9L11_RS22215	COG1024	Enoyl-CoA hydratase
H9L11_RS22220	COG1960	acyl-CoA dehydrogenase activity
H9L11_RS22230	COG0183	Belongs to the thiolase family
H9L11_RS22240	COG1960	acyl-CoA dehydrogenase activity
H9L11_RS22245	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
H9L11_RS22255	COG4770	biotin carboxylase activity
H9L11_RS22270	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
H9L11_RS22270	COG3264	Mechanosensitive ion channel
H9L11_RS22275	COG0110	maltose O-acetyltransferase activity
H9L11_RS22280	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H9L11_RS22285	COG1271	oxidase subunit
H9L11_RS22290	COG1294	oxidase, subunit
H9L11_RS22305	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H9L11_RS22315	COG3527	Alpha-acetolactate decarboxylase
H9L11_RS22325	COG1028	Short-chain dehydrogenase reductase Sdr
H9L11_RS22330	COG0500	methyltransferase
H9L11_RS22360	COG1022	Amp-dependent synthetase and ligase
H9L11_RS22385	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H9L11_RS22390	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9L11_RS22390	COG1263	PTS System
H9L11_RS22395	COG1486	melibiose metabolic process
H9L11_RS22400	COG2188	Transcriptional regulator
H9L11_RS22405	COG1320	monovalent cation:proton antiporter activity
H9L11_RS22410	COG2212	antiporter activity
H9L11_RS22415	COG1863	multisubunit Na H antiporter MnhE subunit
H9L11_RS22420	COG0651	ATP synthesis coupled electron transport
H9L11_RS22425	COG1006	Multisubunit Na H antiporter MnhC subunit
H9L11_RS22430	COG2111	Na H antiporter
H9L11_RS22430	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
H9L11_RS22440	COG0589	response to stress
H9L11_RS22445	COG4221	oxidoreductase activity
H9L11_RS22450	COG0583	DNA-binding transcription factor activity
H9L11_RS22460	COG2814	Major facilitator Superfamily
H9L11_RS22525	COG1522	sequence-specific DNA binding
H9L11_RS22560	COG0515	serine threonine protein kinase
H9L11_RS22585	COG3501	Rhs element vgr protein
H9L11_RS22625	COG0739	heme binding
H9L11_RS22650	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H9L11_RS22655	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H9L11_RS22665	COG2207	Transcriptional regulator
H9L11_RS22670	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H9L11_RS22670	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H9L11_RS22670	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H9L11_RS22685	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H9L11_RS22705	COG3537	Alpha-1,2-mannosidase
H9L11_RS22710	COG3537	Alpha-1,2-mannosidase
H9L11_RS22725	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
H9L11_RS22725	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
H9L11_RS22740	COG4989	oxidoreductase activity
H9L11_RS22755	COG0038	chloride channel
H9L11_RS22790	COG2897	thiosulfate sulfurtransferase activity
H9L11_RS22800	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
H9L11_RS22805	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
H9L11_RS22810	COG0840	transmembrane signaling receptor activity
H9L11_RS22815	COG2814	Major facilitator Superfamily
H9L11_RS22820	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
H9L11_RS22835	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H9L11_RS22845	COG0840	transmembrane signaling receptor activity
H9L11_RS22865	COG2195	Cleaves the N-terminal amino acid of tripeptides
H9L11_RS22880	COG2197	response regulator
H9L11_RS22885	COG3850	Histidine kinase
H9L11_RS22890	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
H9L11_RS22900	COG0243	molybdopterin cofactor binding
H9L11_RS22910	COG3005	denitrification pathway
H9L11_RS22920	COG3243	poly(R)-hydroxyalkanoic acid synthase
H9L11_RS22930	COG0183	Belongs to the thiolase family
H9L11_RS22940	COG1280	lysine exporter protein (LysE YggA)
H9L11_RS22950	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H9L11_RS22955	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H9L11_RS23010	COG2205	protein histidine kinase activity
H9L11_RS23010	COG0784	Response regulator, receiver
H9L11_RS23015	COG1879	ABC-type sugar transport system periplasmic component
H9L11_RS23020	COG2827	Endonuclease containing a URI domain
H9L11_RS23025	COG3132	Protein of unknown function, DUF480
H9L11_RS23045	COG2205	protein histidine kinase activity
H9L11_RS23045	COG0784	Response regulator, receiver
H9L11_RS23045	COG5002	protein histidine kinase activity
H9L11_RS23070	COG0583	DNA-binding transcription factor activity
H9L11_RS23080	COG0531	amino acid
H9L11_RS23095	COG2205	protein histidine kinase activity
H9L11_RS23100	COG0745	RESPONSE REGULATOR receiver
H9L11_RS23125	COG1566	PFAM secretion protein HlyD family protein
H9L11_RS23130	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
H9L11_RS23135	COG2239	Acts as a magnesium transporter
H9L11_RS23140	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
H9L11_RS23145	COG0402	S-adenosylhomocysteine deaminase activity
H9L11_RS23150	COG1418	mRNA catabolic process
H9L11_RS23160	COG2814	Major facilitator Superfamily
H9L11_RS23170	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
H9L11_RS23190	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H9L11_RS23205	COG0745	RESPONSE REGULATOR receiver
H9L11_RS23210	COG2205	protein histidine kinase activity
H9L11_RS23220	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
H9L11_RS23225	COG2194	sulfuric ester hydrolase activity
H9L11_RS23245	COG4667	esterase of the alpha-beta hydrolase superfamily
H9L11_RS23250	COG1741	Belongs to the pirin family
H9L11_RS23255	COG1278	Cold shock
H9L11_RS23270	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
H9L11_RS23275	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
H9L11_RS23275	COG0678	peroxiredoxin activity
H9L11_RS23285	COG1686	Belongs to the peptidase S11 family
H9L11_RS23290	COG0625	glutathione transferase activity
H9L11_RS23295	COG1621	beta-fructofuranosidase activity
H9L11_RS23300	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H9L11_RS23305	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9L11_RS23305	COG1263	PTS System
H9L11_RS23330	COG1028	Short-chain dehydrogenase reductase Sdr
H9L11_RS23345	COG3746	phosphate-selective porin O and P
H9L11_RS23360	COG0300	oxidoreductase activity
H9L11_RS23365	COG0583	DNA-binding transcription factor activity
H9L11_RS23370	COG2207	Transcriptional regulator
H9L11_RS23370	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H9L11_RS23375	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H9L11_RS23395	COG0513	Belongs to the DEAD box helicase family
H9L11_RS23405	COG0583	DNA-binding transcription factor activity
H9L11_RS23420	COG1902	pentaerythritol trinitrate reductase activity
H9L11_RS23425	COG1063	alcohol dehydrogenase
H9L11_RS23435	COG1028	Short-chain dehydrogenase reductase Sdr
H9L11_RS23445	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H9L11_RS23450	COG0006	proline dipeptidase activity
H9L11_RS23455	COG3608	succinylglutamate desuccinylase aspartoacylase
H9L11_RS23460	COG1522	sequence-specific DNA binding
H9L11_RS23465	COG1012	belongs to the aldehyde dehydrogenase family
H9L11_RS23470	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
H9L11_RS23475	COG3122	Protein conserved in bacteria
H9L11_RS23490	COG0583	DNA-binding transcription factor activity