locus-tag	class	description
Vspart_RS00010	COG0592	DNA-directed DNA polymerase activity
Vspart_RS00020	COG0187	DNA topoisomerase II activity
Vspart_RS00025	COG0071	Belongs to the small heat shock protein (HSP20) family
Vspart_RS00040	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
Vspart_RS00050	COG3977	Valine--pyruvate aminotransferase
Vspart_RS00065	COG0439	Biotin carboxylase
Vspart_RS00095	COG0751	glycine-tRNA ligase activity
Vspart_RS00100	COG0752	glycyl-tRNA synthetase alpha subunit
Vspart_RS00110	COG2119	membrane
Vspart_RS00120	COG3501	Rhs element vgr protein
Vspart_RS00175	COG0425	Belongs to the sulfur carrier protein TusA family
Vspart_RS00190	COG0129	dihydroxy-acid dehydratase activity
Vspart_RS00195	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Vspart_RS00200	COG3978	acetolactate synthase activity
Vspart_RS00210	COG0606	chelatase, subunit chli
Vspart_RS00215	COG0204	Acyl-transferase
Vspart_RS00220	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
Vspart_RS00225	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
Vspart_RS00235	COG3084	Protein conserved in bacteria
Vspart_RS00240	COG4326	sporulation control protein
Vspart_RS00245	COG1272	protein, Hemolysin III
Vspart_RS00250	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
Vspart_RS00255	COG0569	domain protein
Vspart_RS00260	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Vspart_RS00260	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
Vspart_RS00275	COG0758	DNA mediated transformation
Vspart_RS00280	COG2922	Belongs to the Smg family
Vspart_RS00285	COG0551	DNA topoisomerase type I activity
Vspart_RS00290	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
Vspart_RS00295	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
Vspart_RS00300	COG0009	L-threonylcarbamoyladenylate synthase
Vspart_RS00320	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
Vspart_RS00350	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Vspart_RS00355	COG0840	transmembrane signaling receptor activity
Vspart_RS00360	COG0583	DNA-binding transcription factor activity
Vspart_RS00365	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
Vspart_RS00370	COG2960	long-chain fatty acid transporting porin activity
Vspart_RS00375	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Vspart_RS00380	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Vspart_RS00420	COG0747	negative chemotaxis
Vspart_RS00430	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Vspart_RS00440	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Vspart_RS00445	COG1172	Belongs to the binding-protein-dependent transport system permease family
Vspart_RS00450	COG1172	Belongs to the binding-protein-dependent transport system permease family
Vspart_RS00455	COG1129	ABC transporter
Vspart_RS00460	COG1879	ABC-type sugar transport system periplasmic component
Vspart_RS00470	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Vspart_RS00475	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
Vspart_RS00490	COG0210	DNA helicase
Vspart_RS00500	COG0405	Gamma-glutamyltransferase
Vspart_RS00505	COG1280	lysine exporter protein (LysE YggA)
Vspart_RS00510	COG2962	Rard protein
Vspart_RS00515	COG0514	ATP-dependent DNA helicase (RecQ)
Vspart_RS00535	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
Vspart_RS00540	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
Vspart_RS00545	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
Vspart_RS00550	COG2723	6-phospho-beta-galactosidase activity
Vspart_RS00555	COG1447	Phosphotransferase system cellobiose-specific component IIA
Vspart_RS00560	COG1609	Transcriptional regulator
Vspart_RS00570	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
Vspart_RS00590	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Vspart_RS00605	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Vspart_RS00615	COG1162	GTPase activity
Vspart_RS00635	COG2003	Belongs to the UPF0758 family
Vspart_RS00650	COG0270	DNA (cytosine-5-)-methyltransferase activity
Vspart_RS00670	COG1561	YicC-like family, N-terminal region
Vspart_RS00675	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
Vspart_RS00680	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
Vspart_RS00685	COG1560	Kdo2-lipid A biosynthetic process
Vspart_RS00690	COG1560	Kdo2-lipid A biosynthetic process
Vspart_RS00695	COG1309	transcriptional regulator
Vspart_RS00700	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
Vspart_RS00705	COG0840	transmembrane signaling receptor activity
Vspart_RS00710	COG2003	Belongs to the UPF0758 family
Vspart_RS00720	COG0267	Belongs to the bacterial ribosomal protein bL33 family
Vspart_RS00735	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
Vspart_RS00740	COG0859	PFAM glycosyl transferase family 9
Vspart_RS00745	COG0463	Glycosyl transferase, family 2
Vspart_RS00750	COG0859	PFAM glycosyl transferase family 9
Vspart_RS00755	COG3642	lipopolysaccharide core region biosynthetic process
Vspart_RS00765	COG1519	Transferase
Vspart_RS00785	COG0859	PFAM glycosyl transferase family 9
Vspart_RS00795	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
Vspart_RS00800	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Vspart_RS00805	COG0662	Cupin 2, conserved barrel domain protein
Vspart_RS00805	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
Vspart_RS00810	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Vspart_RS00845	COG0438	transferase activity, transferring glycosyl groups
Vspart_RS00865	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
Vspart_RS00880	COG3959	Transketolase, thiamine diphosphate binding domain
Vspart_RS00885	COG3958	Transketolase
Vspart_RS00890	COG3958	Transketolase
Vspart_RS00900	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Vspart_RS00945	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Vspart_RS00955	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Vspart_RS00990	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Vspart_RS01000	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Vspart_RS01005	COG3959	Transketolase, thiamine diphosphate binding domain
Vspart_RS01010	COG3958	Transketolase
Vspart_RS01025	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
Vspart_RS01030	COG1088	dTDP-glucose 4,6-dehydratase activity
Vspart_RS01035	COG1215	transferase activity, transferring glycosyl groups
Vspart_RS01060	COG3068	Protein conserved in bacteria
Vspart_RS01065	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Vspart_RS01070	COG1573	uracil-dna glycosylase
Vspart_RS01075	COG0776	regulation of translation
Vspart_RS01090	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Vspart_RS01095	COG0745	RESPONSE REGULATOR receiver
Vspart_RS01100	COG2205	protein histidine kinase activity
Vspart_RS01105	COG2814	Major facilitator Superfamily
Vspart_RS01110	COG1566	PFAM secretion protein HlyD family protein
Vspart_RS01125	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
Vspart_RS01130	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
Vspart_RS01140	COG0194	GDP metabolic process
Vspart_RS01145	COG1301	dicarboxylic acid transport
Vspart_RS01150	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
Vspart_RS01155	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Vspart_RS01170	COG4232	protein-disulfide reductase activity
Vspart_RS01175	COG1027	Aspartate ammonia-lyase
Vspart_RS01180	COG5002	protein histidine kinase activity
Vspart_RS01180	COG3447	MASE1 domain protein
Vspart_RS01180	COG5001	Diguanylate cyclase
Vspart_RS01185	COG3030	protein affecting phage T7 exclusion by the F plasmid
Vspart_RS01190	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
Vspart_RS01220	COG2205	protein histidine kinase activity
Vspart_RS01225	COG0745	RESPONSE REGULATOR receiver
Vspart_RS01235	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
Vspart_RS01245	COG0205	6-phosphofructokinase activity
Vspart_RS01250	COG1494	fructose-1,6-bisphosphatase
Vspart_RS01260	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
Vspart_RS01265	COG0460	homoserine dehydrogenase
Vspart_RS01265	COG0527	aspartate kinase activity
Vspart_RS01270	COG0626	cystathionine gamma-synthase activity
Vspart_RS01275	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
Vspart_RS01285	COG0281	malic enzyme
Vspart_RS01290	COG0254	rRNA binding
Vspart_RS01295	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
Vspart_RS01300	COG1609	Transcriptional regulator
Vspart_RS01310	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
Vspart_RS01315	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
Vspart_RS01320	COG1575	Belongs to the MenA family. Type 1 subfamily
Vspart_RS01330	COG0534	Mate efflux family protein
Vspart_RS01360	COG0459	protein refolding
Vspart_RS01365	COG1119	ATPase activity
Vspart_RS01375	COG1509	lysine 2,3-aminomutase activity
Vspart_RS01380	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
Vspart_RS01390	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
Vspart_RS01395	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
Vspart_RS01400	COG1053	succinate dehydrogenase
Vspart_RS01405	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
Vspart_RS01410	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Vspart_RS01415	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
Vspart_RS01420	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
Vspart_RS01425	COG1045	serine acetyltransferase
Vspart_RS01430	COG1695	Transcriptional regulator
Vspart_RS01435	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
Vspart_RS01440	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Vspart_RS01445	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
Vspart_RS01450	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
Vspart_RS01455	COG0137	argininosuccinate synthase activity
Vspart_RS01470	COG0678	peroxiredoxin activity
Vspart_RS01470	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
Vspart_RS01480	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
Vspart_RS01505	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
Vspart_RS01520	COG0338	D12 class N6 adenine-specific DNA methyltransferase
Vspart_RS01525	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
Vspart_RS01535	COG0180	Tryptophanyl-tRNA synthetase
Vspart_RS01540	COG0446	pyridine nucleotide-disulphide oxidoreductase
Vspart_RS01550	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
Vspart_RS01565	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
Vspart_RS01575	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Vspart_RS01580	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Vspart_RS01590	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Vspart_RS01605	COG1028	Short-chain dehydrogenase reductase Sdr
Vspart_RS01610	COG1028	Short-chain dehydrogenase reductase Sdr
Vspart_RS01635	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Vspart_RS01655	COG3954	Phosphoribulokinase
Vspart_RS01665	COG0429	hydrolase of the alpha beta-hydrolase fold
Vspart_RS01675	COG0488	(ABC) transporter
Vspart_RS01680	COG2249	NAD(P)H dehydrogenase (quinone) activity
Vspart_RS01695	COG1047	Peptidyl-prolyl cis-trans
Vspart_RS01700	COG1446	asparaginase
Vspart_RS01705	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
Vspart_RS01710	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
Vspart_RS01715	COG0557	exoribonuclease II activity
Vspart_RS01720	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Vspart_RS01725	COG0051	transcription antitermination factor activity, RNA binding
Vspart_RS01730	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
Vspart_RS01745	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Vspart_RS01750	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
Vspart_RS01755	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
Vspart_RS01765	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
Vspart_RS01775	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
Vspart_RS01780	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
Vspart_RS01785	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
Vspart_RS01790	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
Vspart_RS01795	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
Vspart_RS01800	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
Vspart_RS01805	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
Vspart_RS01810	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
Vspart_RS01820	COG1841	ribosomal large subunit assembly
Vspart_RS01830	COG0201	protein transport
Vspart_RS01835	COG0257	Belongs to the bacterial ribosomal protein bL36 family
Vspart_RS01840	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Vspart_RS01845	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
Vspart_RS01860	COG0203	ribosomal protein L17
Vspart_RS01870	COG0545	Peptidyl-prolyl cis-trans isomerase
Vspart_RS01880	COG2153	protein acetylation
Vspart_RS01890	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Vspart_RS01890	COG1648	precorrin-2 dehydrogenase activity
Vspart_RS01900	COG2895	sulfate adenylyltransferase (ATP) activity
Vspart_RS01905	COG3273	potassium ion transport
Vspart_RS01905	COG0471	metal ion transport
Vspart_RS01910	COG0529	Catalyzes the synthesis of activated sulfate
Vspart_RS01930	COG1136	(ABC) transporter
Vspart_RS01945	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Vspart_RS01950	COG0729	surface antigen
Vspart_RS01955	COG2911	Protein conserved in bacteria
Vspart_RS01960	COG2105	PFAM AIG2 family protein
Vspart_RS01965	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
Vspart_RS01975	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
Vspart_RS01980	COG0163	prenyltransferase activity
Vspart_RS01985	COG4143	(ABC) transporter
Vspart_RS01990	COG1178	ABC-type Fe3 transport system permease component
Vspart_RS01995	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
Vspart_RS02000	COG3028	Belongs to the UPF0307 family
Vspart_RS02005	COG0312	modulator of DNA gyrase
Vspart_RS02030	COG2239	Acts as a magnesium transporter
Vspart_RS02035	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
Vspart_RS02040	COG1660	Displays ATPase and GTPase activities
Vspart_RS02045	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
Vspart_RS02050	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
Vspart_RS02060	COG1137	ATPase activity
Vspart_RS02075	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
Vspart_RS02080	COG0517	IMP dehydrogenase activity
Vspart_RS02080	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
Vspart_RS02090	COG1127	ABC transporter
Vspart_RS02095	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
Vspart_RS02100	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
Vspart_RS02105	COG2854	intermembrane phospholipid transfer
Vspart_RS02115	COG5007	Belongs to the BolA IbaG family
Vspart_RS02120	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
Vspart_RS02125	COG0204	Acyl-transferase
Vspart_RS02130	COG0251	oxidation-reduction process
Vspart_RS02135	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
Vspart_RS02145	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
Vspart_RS02150	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
Vspart_RS02160	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Vspart_RS02170	COG0564	pseudouridine synthase activity
Vspart_RS02175	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Vspart_RS02180	COG4269	membrane
Vspart_RS02190	COG0501	Belongs to the peptidase M48B family
Vspart_RS02195	COG0525	valine-tRNA ligase activity
Vspart_RS02200	COG2927	DNA polymerase III (CHI subunit)
Vspart_RS02205	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
Vspart_RS02210	COG0795	lipopolysaccharide-transporting ATPase activity
Vspart_RS02215	COG0795	lipopolysaccharide-transporting ATPase activity
Vspart_RS02300	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
Vspart_RS02350	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
Vspart_RS02355	COG0473	3-isopropylmalate dehydrogenase activity
Vspart_RS02360	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Vspart_RS02375	COG0583	DNA-binding transcription factor activity
Vspart_RS02380	COG0028	Belongs to the TPP enzyme family
Vspart_RS02390	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Vspart_RS02395	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
Vspart_RS02400	COG1012	belongs to the aldehyde dehydrogenase family
Vspart_RS02405	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Vspart_RS02415	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Vspart_RS02420	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Vspart_RS02425	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
Vspart_RS02430	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
Vspart_RS02440	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
Vspart_RS02450	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Vspart_RS02455	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Vspart_RS02475	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
Vspart_RS02485	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
Vspart_RS02505	COG3086	response to oxidative stress
Vspart_RS02510	COG0481	GTPase activity
Vspart_RS02520	COG0571	ribonuclease III activity
Vspart_RS02525	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
Vspart_RS02530	COG1381	Involved in DNA repair and RecF pathway recombination
Vspart_RS02535	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
Vspart_RS02540	COG0736	holo-[acyl-carrier-protein] synthase activity
Vspart_RS02545	COG4999	Histidine kinase
Vspart_RS02545	COG2205	protein histidine kinase activity
Vspart_RS02545	COG3437	response regulator, receiver
Vspart_RS02545	COG3850	Histidine kinase
Vspart_RS02555	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
Vspart_RS02560	COG3956	TIGRFAM MazG family protein
Vspart_RS02565	COG0504	CTP synthase activity
Vspart_RS02570	COG0148	phosphopyruvate hydratase activity
Vspart_RS02575	COG0617	tRNA 3'-terminal CCA addition
Vspart_RS02580	COG4991	sh3 domain protein
Vspart_RS02585	COG0306	phosphate transporter
Vspart_RS02590	COG1392	Phosphate transport regulator
Vspart_RS02595	COG3025	triphosphatase activity
Vspart_RS02605	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
Vspart_RS02610	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
Vspart_RS02610	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
Vspart_RS02615	COG1538	Outer membrane efflux protein
Vspart_RS02620	COG0494	nUDIX hydrolase
Vspart_RS02625	COG3151	Protein conserved in bacteria
Vspart_RS02635	COG3150	esterase
Vspart_RS02640	COG0187	DNA topoisomerase II activity
Vspart_RS02645	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
Vspart_RS02660	COG3220	belongs to the UPF0276 family
Vspart_RS02675	COG1595	DNA-templated transcription, initiation
Vspart_RS02685	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
Vspart_RS02690	COG0237	dephospho-CoA kinase activity
Vspart_RS02700	COG1459	type II secretion system
Vspart_RS02705	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Vspart_RS02720	COG0157	Belongs to the NadC ModD family
Vspart_RS02730	COG0716	FMN binding
Vspart_RS02735	COG4974	Belongs to the 'phage' integrase family
Vspart_RS02740	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
Vspart_RS02745	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
Vspart_RS02750	COG2186	Transcriptional regulator
Vspart_RS02755	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
Vspart_RS02760	COG0508	dehydrogenase complex catalyzes the overall conversion of
Vspart_RS02765	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Vspart_RS02780	COG0288	reversible hydration of carbon dioxide
Vspart_RS02785	COG1131	(ABC) transporter
Vspart_RS02790	COG0842	Transport permease protein
Vspart_RS02800	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
Vspart_RS02805	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Vspart_RS02810	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Vspart_RS02815	COG0235	Class ii aldolase
Vspart_RS02825	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
Vspart_RS02830	COG1414	Transcriptional regulator
Vspart_RS02835	COG3623	hexulose-6-phosphate isomerase
Vspart_RS02840	COG1129	ABC transporter
Vspart_RS02845	COG1172	Belongs to the binding-protein-dependent transport system permease family
Vspart_RS02870	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
Vspart_RS02880	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
Vspart_RS02885	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
Vspart_RS02895	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Vspart_RS02900	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
Vspart_RS02905	COG1489	DNA binding
Vspart_RS02910	COG1643	Atp-dependent helicase
Vspart_RS02915	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Vspart_RS02920	COG1049	propionate catabolic process, 2-methylcitrate cycle
Vspart_RS02925	COG3112	Uncharacterised protein family (UPF0231)
Vspart_RS02935	COG0004	ammonium transporteR
Vspart_RS02945	COG0628	permease
Vspart_RS02950	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
Vspart_RS02955	COG0316	Belongs to the HesB IscA family
Vspart_RS02965	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
Vspart_RS02975	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
Vspart_RS02980	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Vspart_RS02985	COG1534	Rna-binding protein
Vspart_RS02990	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
Vspart_RS02995	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Vspart_RS03000	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
Vspart_RS03010	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
Vspart_RS03025	COG0779	Required for maturation of 30S ribosomal subunits
Vspart_RS03030	COG0195	Participates in both transcription termination and antitermination
Vspart_RS03035	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
Vspart_RS03045	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
Vspart_RS03050	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
Vspart_RS03055	COG1185	polyribonucleotide nucleotidyltransferase activity
Vspart_RS03065	COG0534	Mate efflux family protein
Vspart_RS03070	COG0826	peptidase U32
Vspart_RS03075	COG0826	peptidase U32
Vspart_RS03085	COG3154	lipid carrier protein
Vspart_RS03090	COG3153	acetyltransferase
Vspart_RS03100	COG0456	acetyltransferase
Vspart_RS03105	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Vspart_RS03115	COG0489	protein tyrosine kinase activity
Vspart_RS03140	COG1216	Glycosyl transferase, family 2
Vspart_RS03140	COG1442	glycosyl transferase family 8
Vspart_RS03145	COG0438	transferase activity, transferring glycosyl groups
Vspart_RS03150	COG1045	serine acetyltransferase
Vspart_RS03155	COG0438	transferase activity, transferring glycosyl groups
Vspart_RS03175	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
Vspart_RS03180	COG0726	polysaccharide deacetylase
Vspart_RS03195	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
Vspart_RS03200	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
Vspart_RS03215	COG0745	RESPONSE REGULATOR receiver
Vspart_RS03230	COG0513	Belongs to the DEAD box helicase family
Vspart_RS03250	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
Vspart_RS03255	COG2204	response regulator
Vspart_RS03265	COG0667	Aldo Keto reductase
Vspart_RS03270	COG3066	DNA modification
Vspart_RS03275	COG0494	nUDIX hydrolase
Vspart_RS03285	COG0730	response to heat
Vspart_RS03290	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
Vspart_RS03295	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
Vspart_RS03300	COG0583	DNA-binding transcription factor activity
Vspart_RS03305	COG0640	Transcriptional regulator
Vspart_RS03315	COG0728	peptidoglycan biosynthetic process
Vspart_RS03320	COG0196	riboflavin kinase activity
Vspart_RS03330	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
Vspart_RS03335	COG1047	Peptidyl-prolyl cis-trans
Vspart_RS03340	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
Vspart_RS03345	COG1966	Carbon starvation protein
Vspart_RS03355	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
Vspart_RS03360	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
Vspart_RS03370	COG3279	Response regulator of the LytR AlgR family
Vspart_RS03375	COG3275	phosphorelay sensor kinase activity
Vspart_RS03380	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
Vspart_RS03385	COG0287	Prephenate dehydrogenase
Vspart_RS03385	COG1605	Chorismate mutase
Vspart_RS03395	COG0488	(ABC) transporter
Vspart_RS03400	COG0741	lytic transglycosylase activity
Vspart_RS03405	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
Vspart_RS03425	COG5001	Diguanylate cyclase
Vspart_RS03430	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
Vspart_RS03435	COG0077	Prephenate dehydratase
Vspart_RS03435	COG1605	Chorismate mutase
Vspart_RS03440	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
Vspart_RS03445	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Vspart_RS03450	COG0564	pseudouridine synthase activity
Vspart_RS03460	COG0542	response to heat
Vspart_RS03530	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
Vspart_RS03540	COG2974	May be involved in recombination
Vspart_RS03545	COG0745	RESPONSE REGULATOR receiver
Vspart_RS03550	COG5002	protein histidine kinase activity
Vspart_RS03560	COG0248	Ppx GppA phosphatase
Vspart_RS03565	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
Vspart_RS03575	COG0581	inorganic phosphate transmembrane transporter activity
Vspart_RS03580	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
Vspart_RS03585	COG0704	Plays a role in the regulation of phosphate uptake
Vspart_RS03590	COG0450	alkyl hydroperoxide reductase
Vspart_RS03595	COG0583	DNA-binding transcription factor activity
Vspart_RS03600	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
Vspart_RS03610	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
Vspart_RS03610	COG0617	tRNA 3'-terminal CCA addition
Vspart_RS03610	COG0517	IMP dehydrogenase activity
Vspart_RS03620	COG0343	queuine tRNA-ribosyltransferase activity
Vspart_RS03625	COG1862	Preprotein translocase
Vspart_RS03630	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Vspart_RS03635	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Vspart_RS03640	COG0483	inositol monophosphate 1-phosphatase activity
Vspart_RS03645	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
Vspart_RS03650	COG1959	2 iron, 2 sulfur cluster binding
Vspart_RS03655	COG1104	cysteine desulfurase activity
Vspart_RS03660	COG0822	iron-sulfur transferase activity
Vspart_RS03665	COG0316	Belongs to the HesB IscA family
Vspart_RS03680	COG0633	Ferredoxin
Vspart_RS03685	COG2975	iron-sulfur cluster assembly
Vspart_RS03695	COG0105	UTP biosynthetic process
Vspart_RS03700	COG0820	rRNA (adenine-C2-)-methyltransferase activity
Vspart_RS03705	COG1426	Protein conserved in bacteria
Vspart_RS03715	COG0124	histidyl-tRNA synthetase
Vspart_RS03720	COG2976	Protein conserved in bacteria
Vspart_RS03725	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Vspart_RS03730	COG1160	GTP binding
Vspart_RS03745	COG0517	IMP dehydrogenase activity
Vspart_RS03745	COG0516	GMP reductase activity
Vspart_RS03750	COG0518	GMP synthase (glutamine-hydrolyzing) activity
Vspart_RS03750	COG0519	Catalyzes the synthesis of GMP from XMP
Vspart_RS03785	COG0667	Aldo Keto reductase
Vspart_RS03790	COG0583	DNA-binding transcription factor activity
Vspart_RS03800	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
Vspart_RS03815	COG1349	DNA-binding transcription factor activity
Vspart_RS03825	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Vspart_RS03830	COG0738	Major facilitator superfamily
Vspart_RS03845	COG0477	Major facilitator Superfamily
Vspart_RS03865	COG0583	DNA-binding transcription factor activity
Vspart_RS03870	COG0789	Transcriptional regulator
Vspart_RS03875	COG0454	-acetyltransferase
Vspart_RS03885	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Vspart_RS03890	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Vspart_RS03900	COG5002	protein histidine kinase activity
Vspart_RS03910	COG1115	amino acid carrier protein
Vspart_RS03925	COG3623	hexulose-6-phosphate isomerase
Vspart_RS03930	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
Vspart_RS03935	COG0561	phosphatase activity
Vspart_RS03970	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Vspart_RS03980	COG2207	Transcriptional regulator
Vspart_RS03985	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Vspart_RS03985	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Vspart_RS03985	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
Vspart_RS03995	COG3550	peptidyl-serine autophosphorylation
Vspart_RS04135	COG2501	S4 domain
Vspart_RS04140	COG0840	transmembrane signaling receptor activity
Vspart_RS04145	COG3711	transcriptional antiterminator
Vspart_RS04150	COG1263	PTS System
Vspart_RS04150	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Vspart_RS04150	COG2190	(PTS) system
Vspart_RS04155	COG1063	alcohol dehydrogenase
Vspart_RS04160	COG1802	Transcriptional regulator
Vspart_RS04165	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Vspart_RS04170	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
Vspart_RS04175	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Vspart_RS04185	COG2721	sulfolactate sulfo-lyase activity
Vspart_RS04230	COG0205	6-phosphofructokinase activity
Vspart_RS04235	COG1881	PFAM PEBP family protein
Vspart_RS04280	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
Vspart_RS04310	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
Vspart_RS04315	COG2867	negative regulation of translational initiation
Vspart_RS04320	COG2914	Belongs to the UPF0125 (RnfH) family
Vspart_RS04325	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Vspart_RS04335	COG0497	DNA recombination
Vspart_RS04345	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
Vspart_RS04355	COG2358	TRAP transporter, solute receptor (TAXI family
Vspart_RS04360	COG0443	Heat shock 70 kDa protein
Vspart_RS04365	COG0484	heat shock protein binding
Vspart_RS04400	COG0583	DNA-binding transcription factor activity
Vspart_RS04410	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
Vspart_RS04420	COG0686	Belongs to the AlaDH PNT family
Vspart_RS04430	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
Vspart_RS04460	COG1720	tRNA m6t6A37 methyltransferase activity
Vspart_RS04465	COG1671	Belongs to the UPF0178 family
Vspart_RS04490	COG3098	single-species biofilm formation
Vspart_RS04495	COG0564	pseudouridine synthase activity
Vspart_RS04500	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
Vspart_RS04505	COG0142	geranyltranstransferase activity
Vspart_RS04510	COG1722	exodeoxyribonuclease VII activity
Vspart_RS04515	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
Vspart_RS04525	COG4989	oxidoreductase activity
Vspart_RS04530	COG0301	tRNA thio-modification
Vspart_RS04530	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Vspart_RS04535	COG0583	DNA-binding transcription factor activity
Vspart_RS04555	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Vspart_RS04560	COG1611	Belongs to the LOG family
Vspart_RS04575	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
Vspart_RS04575	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
Vspart_RS04585	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
Vspart_RS04590	COG1464	Belongs to the NlpA lipoprotein family
Vspart_RS04595	COG2011	ABC-type metal ion transport system permease component
Vspart_RS04600	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
Vspart_RS04605	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
Vspart_RS04620	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
Vspart_RS04625	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
Vspart_RS04635	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
Vspart_RS04655	COG1686	Belongs to the peptidase S11 family
Vspart_RS04660	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
Vspart_RS04670	COG0768	penicillin binding
Vspart_RS04675	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
Vspart_RS04680	COG0799	negative regulation of ribosome biogenesis
Vspart_RS04685	COG1466	dna polymerase III delta subunit
Vspart_RS04690	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
Vspart_RS04695	COG0495	leucyl-tRNA aminoacylation
Vspart_RS04705	COG0815	Transfers the fatty acyl group on membrane lipoproteins
Vspart_RS04710	COG4535	Mg2 and Co2 transporter CorC
Vspart_RS04715	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
Vspart_RS04720	COG1702	phosphate starvation-inducible protein PhoH
Vspart_RS04730	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Vspart_RS04735	COG2190	(PTS) system
Vspart_RS04740	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Vspart_RS04745	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
Vspart_RS04750	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
Vspart_RS04755	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
Vspart_RS04760	COG3115	cell septum assembly
Vspart_RS04765	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
Vspart_RS04770	COG0789	Transcriptional regulator
Vspart_RS04775	COG3118	belongs to the thioredoxin family
Vspart_RS04780	COG0300	oxidoreductase activity
Vspart_RS04785	COG1090	epimerase
Vspart_RS04820	COG3710	Transcriptional regulator
Vspart_RS04825	COG0326	Molecular chaperone. Has ATPase activity
Vspart_RS04830	COG0563	adenylate kinase activity
Vspart_RS04835	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
Vspart_RS04845	COG0367	asparagine synthase
Vspart_RS04850	COG1940	carbohydrate kinase activity
Vspart_RS04850	COG1846	Transcriptional regulator
Vspart_RS04865	COG0101	tRNA pseudouridine synthase activity
Vspart_RS04870	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
Vspart_RS04875	COG0285	dihydrofolate synthase activity
Vspart_RS04880	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
Vspart_RS04885	COG1286	toxin biosynthetic process
Vspart_RS04890	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
Vspart_RS04895	COG2056	Na+-H+ antiporter family
Vspart_RS04900	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
Vspart_RS04910	COG0346	lactoylglutathione lyase activity
Vspart_RS04915	COG2186	Transcriptional regulator
Vspart_RS04925	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Vspart_RS04930	COG4660	Part of a membrane complex involved in electron transport
Vspart_RS04940	COG4658	electron transport chain
Vspart_RS04945	COG4656	Part of a membrane complex involved in electron transport
Vspart_RS04950	COG2878	Part of a membrane complex involved in electron transport
Vspart_RS04955	COG4657	Part of a membrane complex involved in electron transport
Vspart_RS04960	COG1028	Short-chain dehydrogenase reductase Sdr
Vspart_RS04970	COG3527	Alpha-acetolactate decarboxylase
Vspart_RS04995	COG0673	inositol 2-dehydrogenase activity
Vspart_RS05005	COG0673	inositol 2-dehydrogenase activity
Vspart_RS05020	COG1940	carbohydrate kinase activity
Vspart_RS05060	COG0556	nucleotide-excision repair
Vspart_RS05065	COG2204	response regulator
Vspart_RS05070	COG2198	Histidine kinase
Vspart_RS05075	COG0391	Required for morphogenesis under gluconeogenic growth conditions
Vspart_RS05080	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Vspart_RS05085	COG0521	Mo-molybdopterin cofactor biosynthetic process
Vspart_RS05090	COG0315	cyclic pyranopterin monophosphate synthase activity
Vspart_RS05095	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
Vspart_RS05100	COG0314	molybdopterin synthase activity
Vspart_RS05120	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Vspart_RS05120	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Vspart_RS05125	COG0489	protein tyrosine kinase activity
Vspart_RS05130	COG0572	uridine kinase
Vspart_RS05135	COG2982	Protein involved in outer membrane biogenesis
Vspart_RS05145	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Vspart_RS05160	COG1250	3-hydroxyacyl-CoA dehydrogenase
Vspart_RS05160	COG1024	Enoyl-CoA hydratase
Vspart_RS05165	COG0778	Nitroreductase
Vspart_RS05170	COG0583	DNA-binding transcription factor activity
Vspart_RS05175	COG0745	RESPONSE REGULATOR receiver
Vspart_RS05180	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
Vspart_RS05205	COG2983	Belongs to the UPF0260 family
Vspart_RS05230	COG1028	Short-chain dehydrogenase reductase Sdr
Vspart_RS05245	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
Vspart_RS05265	COG0402	S-adenosylhomocysteine deaminase activity
Vspart_RS05275	COG2986	histidine ammonia-lyase
Vspart_RS05280	COG1228	amidohydrolase
Vspart_RS05290	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
Vspart_RS05295	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
Vspart_RS05300	COG2831	hemolysin activation secretion protein
Vspart_RS05305	COG3210	domain, Protein
Vspart_RS05305	COG3210	domain, Protein
Vspart_RS05350	COG2207	Transcriptional regulator
Vspart_RS05355	COG1028	Short-chain dehydrogenase reductase Sdr
Vspart_RS05365	COG0531	amino acid
Vspart_RS05375	COG4303	Ethanolamine ammonia lyase large subunit
Vspart_RS05415	COG4628	conserved protein (DUF2132)
Vspart_RS05420	COG2199	diguanylate cyclase activity
Vspart_RS05420	COG2203	Gaf domain
Vspart_RS05435	COG0251	oxidation-reduction process
Vspart_RS05440	COG0814	amino acid
Vspart_RS05455	COG0747	negative chemotaxis
Vspart_RS05465	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Vspart_RS05470	COG0444	Belongs to the ABC transporter superfamily
Vspart_RS05475	COG4608	Belongs to the ABC transporter superfamily
Vspart_RS05510	COG2814	Major facilitator Superfamily
Vspart_RS05525	COG4166	transmembrane transport
Vspart_RS05530	COG0601	transmembrane transport
Vspart_RS05540	COG4172	Belongs to the ABC transporter superfamily
Vspart_RS05545	COG0436	Aminotransferase
Vspart_RS05550	COG1169	isochorismate synthase
Vspart_RS05555	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
Vspart_RS05560	COG0596	Alpha beta hydrolase
Vspart_RS05565	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
Vspart_RS05585	COG2855	membrane
Vspart_RS05605	COG1335	isochorismatase
Vspart_RS05615	COG1522	sequence-specific DNA binding
Vspart_RS05620	COG1946	Acyl-CoA thioesterase
Vspart_RS05665	COG0515	serine threonine protein kinase
Vspart_RS05665	COG2815	serine threonine protein kinase
Vspart_RS05700	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Vspart_RS05710	COG2223	nitrite transmembrane transporter activity
Vspart_RS05715	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
Vspart_RS05725	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
Vspart_RS05730	COG2181	nitrate reductase activity
Vspart_RS05735	COG2197	response regulator
Vspart_RS05740	COG3850	Histidine kinase
Vspart_RS05750	COG5297	Belongs to the glycosyl hydrolase family 6
Vspart_RS05760	COG0784	Response regulator, receiver
Vspart_RS05760	COG2205	protein histidine kinase activity
Vspart_RS05760	COG5002	protein histidine kinase activity
Vspart_RS05770	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Vspart_RS05775	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Vspart_RS05775	COG2207	Transcriptional regulator
Vspart_RS05780	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
Vspart_RS05825	COG5002	protein histidine kinase activity
Vspart_RS05830	COG4145	pantothenate transmembrane transporter activity
Vspart_RS05840	COG1349	DNA-binding transcription factor activity
Vspart_RS05845	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
Vspart_RS05850	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
Vspart_RS05855	COG1882	Formate acetyltransferase
Vspart_RS05860	COG1879	ABC-type sugar transport system periplasmic component
Vspart_RS05875	COG0840	transmembrane signaling receptor activity
Vspart_RS05885	COG2226	methyltransferase
Vspart_RS05890	COG0676	glucose-6-phosphate 1-epimerase activity
Vspart_RS05895	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
Vspart_RS05900	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Vspart_RS05910	COG3139	Protein of unknown function (DUF1315)
Vspart_RS05915	COG0252	asparaginase activity
Vspart_RS05920	COG0616	signal peptide processing
Vspart_RS05925	COG0788	formyltetrahydrofolate deformylase activity
Vspart_RS05935	COG1199	ATP-dependent helicase activity
Vspart_RS05940	COG1214	PFAM Peptidase M22, glycoprotease
Vspart_RS05955	COG0596	Alpha beta hydrolase
Vspart_RS05960	COG0318	PFAM AMP-dependent synthetase and ligase
Vspart_RS05965	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
Vspart_RS05970	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
Vspart_RS05975	COG2894	cell division
Vspart_RS05985	COG3100	YcgL domain-containing protein
Vspart_RS05990	COG2951	lytic endotransglycosylase activity
Vspart_RS06035	COG2373	Large extracellular alpha-helical protein
Vspart_RS06040	COG4953	penicillin-binding protein 1C
Vspart_RS06045	COG4628	conserved protein (DUF2132)
Vspart_RS06055	COG0662	Cupin 2, conserved barrel domain protein
Vspart_RS06090	COG2169	Transcriptional regulator
Vspart_RS06090	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
Vspart_RS06105	COG1940	carbohydrate kinase activity
Vspart_RS06105	COG1846	Transcriptional regulator
Vspart_RS06110	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
Vspart_RS06115	COG0363	glucosamine-6-phosphate deaminase activity
Vspart_RS06120	COG2190	(PTS) system
Vspart_RS06120	COG1263	PTS System
Vspart_RS06120	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Vspart_RS06125	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
Vspart_RS06135	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Vspart_RS06140	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
Vspart_RS06145	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Vspart_RS06150	COG0740	serine-type endopeptidase activity
Vspart_RS06160	COG4191	Histidine kinase
Vspart_RS06180	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
Vspart_RS06185	COG0776	regulation of translation
Vspart_RS06190	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Vspart_RS06195	COG1555	photosystem II stabilization
Vspart_RS06215	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
Vspart_RS06220	COG0539	negative regulation of cytoplasmic translation
Vspart_RS06230	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
Vspart_RS06235	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
Vspart_RS06240	COG0284	orotidine-5'-phosphate decarboxylase activity
Vspart_RS06255	COG0583	DNA-binding transcription factor activity
Vspart_RS06260	COG1522	sequence-specific DNA binding
Vspart_RS06265	COG1674	ftsk spoiiie
Vspart_RS06270	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
Vspart_RS06275	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
Vspart_RS06280	COG2186	Transcriptional regulator
Vspart_RS06290	COG0537	adenosine 5'-monophosphoramidase activity
Vspart_RS06320	COG1252	NADH dehydrogenase
Vspart_RS06370	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
Vspart_RS06380	COG4591	ABC-type transport system involved in lipoprotein release permease component
Vspart_RS06385	COG1136	(ABC) transporter
Vspart_RS06390	COG4591	ABC-type transport system involved in lipoprotein release permease component
Vspart_RS06400	COG2333	competence protein COMEC
Vspart_RS06400	COG0658	competence protein
Vspart_RS06405	COG1132	(ABC) transporter
Vspart_RS06410	COG1663	tetraacyldisaccharide 4'-kinase activity
Vspart_RS06420	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
Vspart_RS06425	COG2719	SpoVR family
Vspart_RS06430	COG2718	Belongs to the UPF0229 family
Vspart_RS06435	COG2766	serine protein kinase
Vspart_RS06440	COG3013	Belongs to the UPF0304 family
Vspart_RS06445	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
Vspart_RS06455	COG1882	Formate acetyltransferase
Vspart_RS06470	COG3923	Primosomal replication protein n
Vspart_RS06475	COG0730	response to heat
Vspart_RS06480	COG1199	ATP-dependent helicase activity
Vspart_RS06485	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
Vspart_RS06495	COG3012	SEC-C Motif Domain Protein
Vspart_RS06500	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Vspart_RS06505	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Vspart_RS06510	COG0215	cysteine-tRNA ligase activity
Vspart_RS06515	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
Vspart_RS06520	COG0632	four-way junction helicase activity
Vspart_RS06530	COG1271	oxidase subunit
Vspart_RS06535	COG1294	oxidase, subunit
Vspart_RS06540	COG4890	Cyd operon protein YbgT
Vspart_RS06545	COG3790	cyd operon protein YbgE
Vspart_RS06550	COG0824	Thioesterase
Vspart_RS06555	COG0811	peptide transport
Vspart_RS06575	COG2885	chlorophyll binding
Vspart_RS06580	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
Vspart_RS06585	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
Vspart_RS06610	COG1028	Short-chain dehydrogenase reductase Sdr
Vspart_RS06610	COG4221	oxidoreductase activity
Vspart_RS06610	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Vspart_RS06610	COG3321	synthase
Vspart_RS06675	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
Vspart_RS06725	COG0604	alcohol dehydrogenase
Vspart_RS06730	COG0431	NADPH-dependent FMN reductase
Vspart_RS06730	COG1053	succinate dehydrogenase
Vspart_RS06730	COG3976	FMN-binding domain protein
Vspart_RS06745	COG2814	Major facilitator Superfamily
Vspart_RS06750	COG3290	protein histidine kinase activity
Vspart_RS06755	COG0471	metal ion transport
Vspart_RS06760	COG4565	transcriptional regulatory protein
Vspart_RS06765	COG2828	Protein conserved in bacteria
Vspart_RS06770	COG1049	propionate catabolic process, 2-methylcitrate cycle
Vspart_RS06775	COG1028	Short-chain dehydrogenase reductase Sdr
Vspart_RS06785	COG0346	lactoylglutathione lyase activity
Vspart_RS06810	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Vspart_RS06815	COG1629	transport
Vspart_RS06815	COG4774	siderophore transport
Vspart_RS06820	COG2382	esterase
Vspart_RS06835	COG1120	ATPase activity
Vspart_RS06840	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Vspart_RS06845	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Vspart_RS06855	COG4592	Periplasmic binding protein
Vspart_RS06860	COG3433	isochorismatase activity
Vspart_RS06860	COG1535	isochorismatase
Vspart_RS06865	COG1021	2,3-dihydroxybenzoate-AMP ligase
Vspart_RS06870	COG1169	isochorismate synthase
Vspart_RS06875	COG1028	Short-chain dehydrogenase reductase Sdr
Vspart_RS06900	COG0765	amino acid transport
Vspart_RS06905	COG0765	amino acid transport
Vspart_RS06910	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Vspart_RS06920	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
Vspart_RS06935	COG3591	Belongs to the peptidase S1B family
Vspart_RS06945	COG2423	ornithine cyclodeaminase activity
Vspart_RS06955	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Vspart_RS06975	COG3501	Rhs element vgr protein
Vspart_RS07010	COG3501	Rhs element vgr protein
Vspart_RS07055	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
Vspart_RS07060	COG3842	ATPase activity
Vspart_RS07075	COG1840	ABC-type Fe3 transport system, periplasmic component
Vspart_RS07080	COG1609	Transcriptional regulator
Vspart_RS07090	COG0739	heme binding
Vspart_RS07110	COG1342	Belongs to the UPF0251 family
Vspart_RS07120	COG1132	(ABC) transporter
Vspart_RS07125	COG1132	(ABC) transporter
Vspart_RS07130	COG1477	protein flavinylation
Vspart_RS07135	COG0569	domain protein
Vspart_RS07140	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
Vspart_RS07150	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
Vspart_RS07155	COG2985	domain, Protein
Vspart_RS07155	COG3273	potassium ion transport
Vspart_RS07160	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
Vspart_RS07165	COG1737	Transcriptional regulator
Vspart_RS07170	COG0076	glutamate decarboxylase activity
Vspart_RS07180	COG3070	regulator of competence-specific genes
Vspart_RS07195	COG4191	Histidine kinase
Vspart_RS07205	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
Vspart_RS07210	COG1032	radical SAM domain protein
Vspart_RS07225	COG1522	sequence-specific DNA binding
Vspart_RS07235	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Vspart_RS07240	COG0765	amino acid transport
Vspart_RS07245	COG1126	abc transporter atp-binding protein
Vspart_RS07260	COG2350	Protein conserved in bacteria
Vspart_RS07265	COG1607	acyl-coa hydrolase
Vspart_RS07285	COG1301	dicarboxylic acid transport
Vspart_RS07290	COG0159	tryptophan synthase activity
Vspart_RS07295	COG0133	tryptophan synthase activity
Vspart_RS07300	COG0135	phosphoribosylanthranilate isomerase activity
Vspart_RS07300	COG0134	indole-3-glycerol-phosphate synthase activity
Vspart_RS07305	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Vspart_RS07310	COG0512	Glutamine amidotransferase of anthranilate synthase
Vspart_RS07315	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
Vspart_RS07325	COG0009	L-threonylcarbamoyladenylate synthase
Vspart_RS07330	COG1187	pseudouridine synthase activity
Vspart_RS07335	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
Vspart_RS07340	COG4988	ABC transporter
Vspart_RS07345	COG0492	ferredoxin-NADP+ reductase activity
Vspart_RS07355	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Vspart_RS07365	COG2949	membrane
Vspart_RS07375	COG0281	malic enzyme
Vspart_RS07385	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
Vspart_RS07415	COG0247	lactate metabolic process
Vspart_RS07415	COG0277	FAD linked oxidase domain protein
Vspart_RS07430	COG3099	Belongs to the UPF0263 family
Vspart_RS07445	COG0417	DNA replication proofreading
Vspart_RS07455	COG2197	response regulator
Vspart_RS07460	COG0322	excinuclease ABC activity
Vspart_RS07470	COG0390	transport system, permease component
Vspart_RS07480	COG4172	Belongs to the ABC transporter superfamily
Vspart_RS07495	COG4168	peptide transport system, permease
Vspart_RS07505	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
Vspart_RS07510	COG1842	Phage shock protein A
Vspart_RS07520	COG1983	PspC domain protein
Vspart_RS07525	COG0626	cystathionine gamma-synthase activity
Vspart_RS07535	COG0840	transmembrane signaling receptor activity
Vspart_RS07540	COG0733	neurotransmitter:sodium symporter activity
Vspart_RS07545	COG0564	pseudouridine synthase activity
Vspart_RS07550	COG0116	Belongs to the methyltransferase superfamily
Vspart_RS07550	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
Vspart_RS07560	COG3313	Fe-S protein
Vspart_RS07575	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
Vspart_RS07580	COG1061	Type III restriction enzyme res subunit
Vspart_RS07585	COG1187	pseudouridine synthase activity
Vspart_RS07590	COG2814	Major facilitator Superfamily
Vspart_RS07600	COG2249	NAD(P)H dehydrogenase (quinone) activity
Vspart_RS07605	COG0583	DNA-binding transcription factor activity
Vspart_RS07670	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
Vspart_RS07670	COG2169	Transcriptional regulator
Vspart_RS07675	COG2176	DNA-directed DNA polymerase activity
Vspart_RS07705	COG1280	lysine exporter protein (LysE YggA)
Vspart_RS07725	COG0702	epimerase
Vspart_RS07735	COG4181	ATPase activity
Vspart_RS07795	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Vspart_RS07800	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Vspart_RS07815	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Vspart_RS07820	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Vspart_RS07835	COG1846	Transcriptional regulator
Vspart_RS07840	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
Vspart_RS07870	COG3290	protein histidine kinase activity
Vspart_RS07875	COG4565	transcriptional regulatory protein
Vspart_RS07895	COG1335	isochorismatase
Vspart_RS07900	COG4565	transcriptional regulatory protein
Vspart_RS07915	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
Vspart_RS07925	COG2301	Belongs to the HpcH HpaI aldolase family
Vspart_RS07945	COG0840	transmembrane signaling receptor activity
Vspart_RS07950	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
Vspart_RS07955	COG1254	Belongs to the acylphosphatase family
Vspart_RS07960	COG2920	part of a sulfur-relay system
Vspart_RS07965	COG0670	Belongs to the BI1 family
Vspart_RS07970	COG1126	abc transporter atp-binding protein
Vspart_RS07975	COG0765	amino acid transport
Vspart_RS07980	COG4597	amino acid ABC transporter
Vspart_RS07985	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Vspart_RS08000	COG1666	GTP binding
Vspart_RS08005	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
Vspart_RS08020	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
Vspart_RS08020	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
Vspart_RS08025	COG1956	GAF domain-containing protein
Vspart_RS08030	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
Vspart_RS08035	COG0793	Belongs to the peptidase S41A family
Vspart_RS08045	COG0308	aminopeptidase N
Vspart_RS08055	COG2902	Dehydrogenase
Vspart_RS08070	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
Vspart_RS08070	COG0116	Belongs to the methyltransferase superfamily
Vspart_RS08090	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Vspart_RS08095	COG1067	ATP-dependent peptidase activity
Vspart_RS08100	COG3120	sequence-specific DNA binding
Vspart_RS08135	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
Vspart_RS08140	COG0574	Belongs to the PEP-utilizing enzyme family
Vspart_RS08140	COG3848	Pyruvate phosphate dikinase
Vspart_RS08145	COG0028	Belongs to the TPP enzyme family
Vspart_RS08155	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
Vspart_RS08155	COG1414	Transcriptional regulator
Vspart_RS08160	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Vspart_RS08165	COG0156	8-amino-7-oxononanoate synthase activity
Vspart_RS08170	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Vspart_RS08190	COG0778	Nitroreductase
Vspart_RS08200	COG2205	protein histidine kinase activity
Vspart_RS08200	COG0784	Response regulator, receiver
Vspart_RS08215	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Vspart_RS08220	COG0589	response to stress
Vspart_RS08225	COG0037	tRNA processing
Vspart_RS08240	COG3842	ATPase activity
Vspart_RS08245	COG1176	ABC-type spermidine putrescine transport system, permease component I
Vspart_RS08250	COG1177	transmembrane transport
Vspart_RS08260	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
Vspart_RS08265	COG0814	amino acid
Vspart_RS08270	COG0004	ammonium transporteR
Vspart_RS08280	COG3829	transcription factor binding
Vspart_RS08285	COG0746	molybdenum cofactor guanylyltransferase activity
Vspart_RS08290	COG1763	Mo-molybdopterin cofactor biosynthetic process
Vspart_RS08295	COG1940	carbohydrate kinase activity
Vspart_RS08300	COG0840	transmembrane signaling receptor activity
Vspart_RS08310	COG3001	Fructosamine kinase
Vspart_RS08315	COG0307	riboflavin synthase, alpha
Vspart_RS08320	COG0534	Mate efflux family protein
Vspart_RS08325	COG1793	dna ligase
Vspart_RS08340	COG0848	biopolymer transport protein
Vspart_RS08345	COG0811	peptide transport
Vspart_RS08350	COG0811	peptide transport
Vspart_RS08360	COG0584	glycerophosphoryl diester phosphodiesterase
Vspart_RS08370	COG1115	amino acid carrier protein
Vspart_RS08385	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
Vspart_RS08395	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
Vspart_RS08405	COG1609	Transcriptional regulator
Vspart_RS08405	COG2207	Transcriptional regulator
Vspart_RS08535	COG4735	regulation of single-species biofilm formation
Vspart_RS08565	COG3842	ATPase activity
Vspart_RS08595	COG0640	Transcriptional regulator
Vspart_RS08600	COG0431	NADPH-dependent FMN reductase
Vspart_RS08605	COG0798	PFAM Bile acid sodium symporter
Vspart_RS08625	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
Vspart_RS08630	COG1085	galactose-1-phosphate uridylyltransferase
Vspart_RS08635	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
Vspart_RS08640	COG0840	transmembrane signaling receptor activity
Vspart_RS08645	COG4580	involved in the transport of maltose and maltodextrins
Vspart_RS08650	COG1874	Beta-galactosidase
Vspart_RS08660	COG3833	ABC-type maltose transport systems, permease component
Vspart_RS08665	COG1175	transmembrane transport
Vspart_RS08675	COG2182	Extracellular solute-binding protein
Vspart_RS08685	COG1609	Transcriptional regulator
Vspart_RS08700	COG0583	DNA-binding transcription factor activity
Vspart_RS08705	COG0431	NADPH-dependent FMN reductase
Vspart_RS08705	COG3976	FMN-binding domain protein
Vspart_RS08705	COG1053	succinate dehydrogenase
Vspart_RS08720	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Vspart_RS08730	COG1643	Atp-dependent helicase
Vspart_RS08745	COG1309	transcriptional regulator
Vspart_RS08770	COG0443	Heat shock 70 kDa protein
Vspart_RS08775	COG0443	Heat shock 70 kDa protein
Vspart_RS08790	COG0602	queuosine metabolic process
Vspart_RS08795	COG0561	phosphatase activity
Vspart_RS08800	COG0456	acetyltransferase
Vspart_RS08810	COG2079	MmgE PrpD family protein
Vspart_RS08815	COG0372	Belongs to the citrate synthase family
Vspart_RS08820	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
Vspart_RS08830	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Vspart_RS08840	COG3768	UPF0283 membrane protein
Vspart_RS08845	COG3106	COG3106 Predicted ATPase
Vspart_RS08885	COG0494	nUDIX hydrolase
Vspart_RS08895	COG1760	l-serine dehydratase
Vspart_RS08900	COG0720	synthase
Vspart_RS08905	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Vspart_RS08905	COG1017	nitric oxide dioxygenase activity
Vspart_RS08915	COG1263	PTS System
Vspart_RS08915	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Vspart_RS08915	COG2190	(PTS) system
Vspart_RS08930	COG0646	methionine synthase
Vspart_RS08930	COG1410	methionine synthase
Vspart_RS08945	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Vspart_RS08950	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Vspart_RS08955	COG1120	ATPase activity
Vspart_RS08960	COG0583	DNA-binding transcription factor activity
Vspart_RS08965	COG4774	siderophore transport
Vspart_RS08970	COG0840	transmembrane signaling receptor activity
Vspart_RS08985	COG3706	GGDEF domain
Vspart_RS08995	COG2249	NAD(P)H dehydrogenase (quinone) activity
Vspart_RS09035	COG3209	COG3209 Rhs family protein
Vspart_RS09055	COG3209	COG3209 Rhs family protein
Vspart_RS09110	COG3209	COG3209 Rhs family protein
Vspart_RS09135	COG3209	COG3209 Rhs family protein
Vspart_RS09160	COG3196	Protein conserved in bacteria
Vspart_RS09165	COG3209	COG3209 Rhs family protein
Vspart_RS09165	COG3209	COG3209 Rhs family protein
Vspart_RS09175	COG3501	Rhs element vgr protein
Vspart_RS09185	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
Vspart_RS09195	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
Vspart_RS09200	COG2181	nitrate reductase activity
Vspart_RS09200	COG0247	lactate metabolic process
Vspart_RS09205	COG1902	pentaerythritol trinitrate reductase activity
Vspart_RS09205	COG0446	pyridine nucleotide-disulphide oxidoreductase
Vspart_RS09225	COG1760	l-serine dehydratase
Vspart_RS09255	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
Vspart_RS09260	COG0017	Asparaginyl-tRNA synthetase
Vspart_RS09265	COG1448	Aminotransferase
Vspart_RS09280	COG0402	S-adenosylhomocysteine deaminase activity
Vspart_RS09295	COG3008	intermembrane lipid transfer
Vspart_RS09295	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
Vspart_RS09300	COG2995	paraquat-inducible protein a
Vspart_RS09315	COG0837	glucose binding
Vspart_RS09350	COG3842	ATPase activity
Vspart_RS09360	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Vspart_RS09400	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
Vspart_RS09495	COG3833	ABC-type maltose transport systems, permease component
Vspart_RS09500	COG1175	transmembrane transport
Vspart_RS09510	COG3842	ATPase activity
Vspart_RS09515	COG1640	4-alpha-glucanotransferase
Vspart_RS09520	COG0058	SHG alpha-glucan phosphorylase activity
Vspart_RS09525	COG2909	trisaccharide binding
Vspart_RS09550	COG2199	diguanylate cyclase activity
Vspart_RS09560	COG0784	Response regulator, receiver
Vspart_RS09560	COG0835	chemotaxis
Vspart_RS09580	COG0583	DNA-binding transcription factor activity
Vspart_RS09600	COG1538	Outer membrane efflux protein
Vspart_RS09615	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
Vspart_RS09620	COG4139	cobalamin transport
Vspart_RS09625	COG2988	succinylglutamate desuccinylase activity
Vspart_RS09630	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
Vspart_RS09765	COG2925	Exonuclease
Vspart_RS09770	COG1380	Effector of murein hydrolase LrgA
Vspart_RS09775	COG1346	cytolysis
Vspart_RS09780	COG0295	cytidine deaminase activity
Vspart_RS09790	COG0500	methyltransferase
Vspart_RS09795	COG0776	regulation of translation
Vspart_RS09800	COG0072	phenylalanine-tRNA ligase activity
Vspart_RS09800	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Vspart_RS09805	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
Vspart_RS09815	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Vspart_RS09850	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Vspart_RS09855	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Vspart_RS09875	COG1435	thymidine kinase activity
Vspart_RS09880	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
Vspart_RS09885	COG1801	Protein of unknown function DUF72
Vspart_RS09890	COG4106	trans-aconitate 2-methyltransferase activity
Vspart_RS09895	COG0500	methyltransferase
Vspart_RS09900	COG4067	protein conserved in archaea
Vspart_RS09900	COG0189	ligase activity
Vspart_RS09910	COG0189	ligase activity
Vspart_RS09915	COG0463	Glycosyl transferase, family 2
Vspart_RS09935	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
Vspart_RS09945	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Vspart_RS09950	COG1434	Gram-negative-bacterium-type cell wall biogenesis
Vspart_RS09955	COG1609	Transcriptional regulator
Vspart_RS09960	COG3070	regulator of competence-specific genes
Vspart_RS09970	COG0297	glycogen (starch) synthase activity
Vspart_RS09980	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
Vspart_RS09990	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
Vspart_RS10005	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
Vspart_RS10010	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
Vspart_RS10015	COG0542	response to heat
Vspart_RS10020	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
Vspart_RS10025	COG1278	Cold shock
Vspart_RS10035	COG1187	pseudouridine synthase activity
Vspart_RS10040	COG0140	phosphoribosyl-ATP diphosphatase activity
Vspart_RS10040	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
Vspart_RS10050	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
Vspart_RS10055	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
Vspart_RS10060	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
Vspart_RS10060	COG0131	Imidazoleglycerol-phosphate dehydratase
Vspart_RS10065	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Vspart_RS10070	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
Vspart_RS10075	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
Vspart_RS10080	COG1757	Na H antiporter
Vspart_RS10085	COG2916	Histone family protein nucleoid-structuring protein H-NS
Vspart_RS10090	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Vspart_RS10095	COG0482	sulfurtransferase activity
Vspart_RS10105	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
Vspart_RS10120	COG0754	glutathionylspermidine amidase activity
Vspart_RS10130	COG1842	Phage shock protein A
Vspart_RS10135	COG0137	argininosuccinate synthase activity
Vspart_RS10145	COG3766	membrane
Vspart_RS10155	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
Vspart_RS10160	COG2226	methyltransferase
Vspart_RS10165	COG0156	8-amino-7-oxononanoate synthase activity
Vspart_RS10170	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
Vspart_RS10220	COG0488	(ABC) transporter
Vspart_RS10245	COG2205	protein histidine kinase activity
Vspart_RS10255	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
Vspart_RS10265	COG0653	protein targeting
Vspart_RS10290	COG4120	Belongs to the binding-protein-dependent transport system permease family
Vspart_RS10300	COG3092	negative regulation of chromosome organization
Vspart_RS10305	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
Vspart_RS10310	COG0857	belongs to the CobB CobQ family
Vspart_RS10310	COG0280	phosphate acetyltransferase
Vspart_RS10315	COG0435	Glutathione S-transferase
Vspart_RS10320	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Vspart_RS10325	COG1621	beta-fructofuranosidase activity
Vspart_RS10335	COG1263	PTS System
Vspart_RS10335	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Vspart_RS10345	COG0745	RESPONSE REGULATOR receiver
Vspart_RS10355	COG4139	cobalamin transport
Vspart_RS10365	COG2204	response regulator
Vspart_RS10375	COG3852	Histidine kinase
Vspart_RS10385	COG3437	response regulator, receiver
Vspart_RS10400	COG0702	epimerase
Vspart_RS10405	COG1733	regulation of RNA biosynthetic process
Vspart_RS10415	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Vspart_RS10420	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Vspart_RS10425	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Vspart_RS10430	COG4948	Mandelate Racemase Muconate Lactonizing
Vspart_RS10440	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
Vspart_RS10445	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
Vspart_RS10450	COG1984	allophanate hydrolase subunit 2
Vspart_RS10455	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
Vspart_RS10460	COG4943	cyclic-guanylate-specific phosphodiesterase activity
Vspart_RS10465	COG2084	Dehydrogenase
Vspart_RS10470	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
Vspart_RS10475	COG3507	Belongs to the glycosyl hydrolase 43 family
Vspart_RS10565	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
Vspart_RS10570	COG0574	Belongs to the PEP-utilizing enzyme family
Vspart_RS10570	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Vspart_RS10575	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Vspart_RS10595	COG1053	succinate dehydrogenase
Vspart_RS10600	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
Vspart_RS10605	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
Vspart_RS10615	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
Vspart_RS10620	COG3290	protein histidine kinase activity
Vspart_RS10625	COG4565	transcriptional regulatory protein
Vspart_RS10635	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
Vspart_RS10640	COG1349	DNA-binding transcription factor activity
Vspart_RS10650	COG2271	Major facilitator Superfamily
Vspart_RS10665	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
Vspart_RS10670	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
Vspart_RS10675	COG0789	Transcriptional regulator
Vspart_RS10685	COG0616	signal peptide processing
Vspart_RS10690	COG1028	Short-chain dehydrogenase reductase Sdr
Vspart_RS10695	COG0784	Response regulator, receiver
Vspart_RS10695	COG0835	chemotaxis
Vspart_RS10700	COG1940	carbohydrate kinase activity
Vspart_RS10705	COG0469	pyruvate kinase activity
Vspart_RS10710	COG4667	esterase of the alpha-beta hydrolase superfamily
Vspart_RS10720	COG0733	neurotransmitter:sodium symporter activity
Vspart_RS10735	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Vspart_RS10735	COG1263	PTS System
Vspart_RS10740	COG0084	hydrolase, TatD family'
Vspart_RS10745	COG0470	DNA polymerase III
Vspart_RS10750	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
Vspart_RS10755	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
Vspart_RS10785	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Vspart_RS10800	COG1399	metal-binding, possibly nucleic acid-binding protein
Vspart_RS10805	COG0424	maF-like protein
Vspart_RS10810	COG0564	pseudouridine synthase activity
Vspart_RS10815	COG1530	ribonuclease E activity
Vspart_RS10820	COG0659	secondary active sulfate transmembrane transporter activity
Vspart_RS10825	COG1454	alcohol dehydrogenase
Vspart_RS10825	COG1012	belongs to the aldehyde dehydrogenase family
Vspart_RS10830	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Vspart_RS10835	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
Vspart_RS10840	COG3081	Nucleoid-associated protein
Vspart_RS10845	COG3082	Protein of unknown function (DUF1414)
Vspart_RS10850	COG3083	sulfuric ester hydrolase activity
Vspart_RS10910	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Vspart_RS10915	COG4597	amino acid ABC transporter
Vspart_RS10920	COG0765	amino acid transport
Vspart_RS10925	COG1126	abc transporter atp-binding protein
Vspart_RS10940	COG1280	lysine exporter protein (LysE YggA)
Vspart_RS10945	COG0252	asparaginase activity
Vspart_RS10965	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Vspart_RS10970	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Vspart_RS10990	COG2272	Belongs to the type-B carboxylesterase lipase family
Vspart_RS11025	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Vspart_RS11030	COG0596	Alpha beta hydrolase
Vspart_RS11045	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Vspart_RS11050	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Vspart_RS11060	COG0318	PFAM AMP-dependent synthetase and ligase
Vspart_RS11090	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Vspart_RS11120	COG2205	protein histidine kinase activity
Vspart_RS11125	COG2204	response regulator
Vspart_RS11130	COG1136	(ABC) transporter
Vspart_RS11130	COG0577	efflux transmembrane transporter activity
Vspart_RS11135	COG1136	(ABC) transporter
Vspart_RS11135	COG0577	efflux transmembrane transporter activity
Vspart_RS11155	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Vspart_RS11160	COG0842	Transport permease protein
Vspart_RS11165	COG1131	(ABC) transporter
Vspart_RS11185	COG0601	transmembrane transport
Vspart_RS11190	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Vspart_RS11205	COG1917	Cupin 2, conserved barrel domain protein
Vspart_RS11205	COG2207	Transcriptional regulator
Vspart_RS11220	COG2130	NADP-dependent
Vspart_RS11230	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
Vspart_RS11235	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
Vspart_RS11265	COG0835	chemotaxis
Vspart_RS11275	COG1192	Involved in chromosome partitioning
Vspart_RS11280	COG2201	protein-glutamate methylesterase activity
Vspart_RS11285	COG2198	Histidine kinase
Vspart_RS11285	COG0643	Histidine kinase
Vspart_RS11285	COG0784	Response regulator, receiver
Vspart_RS11290	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
Vspart_RS11320	COG2062	phosphohistidine phosphatase, SixA
Vspart_RS11325	COG1025	Belongs to the peptidase M16 family
Vspart_RS11330	COG3102	Protein conserved in bacteria
Vspart_RS11360	COG1918	ferrous iron import across plasma membrane
Vspart_RS11365	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
Vspart_RS11370	COG1121	(ABC) transporter
Vspart_RS11375	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Vspart_RS11380	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
Vspart_RS11390	COG0508	dehydrogenase complex catalyzes the overall conversion of
Vspart_RS11395	COG0567	Dehydrogenase, E1 component
Vspart_RS11405	COG1053	succinate dehydrogenase
Vspart_RS11410	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
Vspart_RS11415	COG2009	succinate dehydrogenase
Vspart_RS11425	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
Vspart_RS11435	COG0033	Phosphoglucomutase
Vspart_RS11440	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
Vspart_RS11445	COG0596	Alpha beta hydrolase
Vspart_RS11450	COG0716	FMN binding
Vspart_RS11455	COG0735	belongs to the Fur family
Vspart_RS11460	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
Vspart_RS11465	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Vspart_RS11470	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Vspart_RS11475	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
Vspart_RS11475	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Vspart_RS11480	COG0431	NADPH-dependent FMN reductase
Vspart_RS11490	COG3101	peptidyl-lysine hydroxylation
Vspart_RS11495	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
Vspart_RS11500	COG2890	protein-(glutamine-N5) methyltransferase activity
Vspart_RS11505	COG2840	Smr protein MutS2
Vspart_RS11515	COG1684	flagellar biosynthetic protein fliR
Vspart_RS11520	COG1987	bacterial-type flagellum assembly
Vspart_RS11545	COG1580	Controls the rotational direction of flagella during chemotaxis
Vspart_RS11570	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Vspart_RS11580	COG1677	Flagellar hook-basal body complex protein FliE
Vspart_RS11590	COG4191	Histidine kinase
Vspart_RS11600	COG1516	flagellar protein fliS
Vspart_RS11610	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
Vspart_RS11615	COG1334	flagellar protein FlaG
Vspart_RS11625	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Vspart_RS11635	COG2837	iron assimilation
Vspart_RS11640	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
Vspart_RS11650	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Vspart_RS11655	COG1136	(ABC) transporter
Vspart_RS11655	COG0577	efflux transmembrane transporter activity
Vspart_RS11665	COG0577	efflux transmembrane transporter activity
Vspart_RS11680	COG0672	)-iron permease
Vspart_RS11690	COG1393	Belongs to the ArsC family
Vspart_RS11700	COG1876	peptidase activity
Vspart_RS11710	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
Vspart_RS11715	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Vspart_RS11720	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Vspart_RS11735	COG4783	chaperone-mediated protein folding
Vspart_RS11740	COG1393	Belongs to the ArsC family
Vspart_RS11760	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
Vspart_RS11765	COG0737	Belongs to the 5'-nucleotidase family
Vspart_RS11770	COG2877	3-deoxy-8-phosphooctulonate synthase activity
Vspart_RS11775	COG2912	Transglutaminase-like superfamily
Vspart_RS11780	COG3094	Invasion gene expression up-regulator, SirB
Vspart_RS11785	COG2890	protein-(glutamine-N5) methyltransferase activity
Vspart_RS11790	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
Vspart_RS11800	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
Vspart_RS11810	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
Vspart_RS11815	COG0193	aminoacyl-tRNA hydrolase activity
Vspart_RS11900	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Vspart_RS11910	COG1705	Flagellar rod assembly protein muramidase FlgJ
Vspart_RS11910	COG3951	Flagellar rod assembly protein muramidase FlgJ
Vspart_RS11920	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
Vspart_RS11930	COG4787	bacterial-type flagellum-dependent cell motility
Vspart_RS11935	COG1749	Flagellar hook protein flgE
Vspart_RS11950	COG1815	bacterial-type flagellum-dependent cell motility
Vspart_RS11955	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
Vspart_RS11960	COG0784	Response regulator, receiver
Vspart_RS11960	COG0835	chemotaxis
Vspart_RS12005	COG3047	cAMP biosynthetic process
Vspart_RS12010	COG0071	Belongs to the small heat shock protein (HSP20) family
Vspart_RS12020	COG1846	Transcriptional regulator
Vspart_RS12040	COG2217	Heavy metal translocating P-type atpase
Vspart_RS12040	COG2608	mercury ion transmembrane transporter activity
Vspart_RS12045	COG3735	TraB family
Vspart_RS12055	COG2840	Smr protein MutS2
Vspart_RS12060	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
Vspart_RS12065	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
Vspart_RS12070	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
Vspart_RS12085	COG1051	belongs to the nudix hydrolase family
Vspart_RS12090	COG0121	glutamine amidotransferase
Vspart_RS12095	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
Vspart_RS12115	COG0328	RNA-DNA hybrid ribonuclease activity
Vspart_RS12120	COG2226	methyltransferase
Vspart_RS12125	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Vspart_RS12130	COG1388	LysM domain
Vspart_RS12130	COG0741	lytic transglycosylase activity
Vspart_RS12150	COG0825	malonyl-CoA metabolic process
Vspart_RS12155	COG0587	DNA-directed DNA polymerase activity
Vspart_RS12160	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
Vspart_RS12170	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Vspart_RS12175	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Vspart_RS12180	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Vspart_RS12185	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
Vspart_RS12195	COG0750	zinc metalloprotease
Vspart_RS12200	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
Vspart_RS12205	COG0575	Belongs to the CDS family
Vspart_RS12210	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
Vspart_RS12220	COG0528	UMP kinase activity
Vspart_RS12225	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
Vspart_RS12230	COG0052	Belongs to the universal ribosomal protein uS2 family
Vspart_RS12235	COG0024	Methionine aminopeptidase
Vspart_RS12250	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
Vspart_RS12255	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
Vspart_RS12260	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Vspart_RS12280	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Vspart_RS12280	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Vspart_RS12285	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
Vspart_RS12310	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
Vspart_RS12315	COG2252	PERMEase
Vspart_RS12320	COG2195	Cleaves the N-terminal amino acid of tripeptides
Vspart_RS12325	COG0189	ligase activity
Vspart_RS12325	COG4067	protein conserved in archaea
Vspart_RS12330	COG0189	ligase activity
Vspart_RS12335	COG0733	neurotransmitter:sodium symporter activity
Vspart_RS12340	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
Vspart_RS12345	COG0697	spore germination
Vspart_RS12350	COG0583	DNA-binding transcription factor activity
Vspart_RS12390	COG1805	sodium ion transport
Vspart_RS12395	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
Vspart_RS12400	COG0271	Belongs to the BolA IbaG family
Vspart_RS12425	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
Vspart_RS12435	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Vspart_RS12440	COG2166	iron-sulfur cluster assembly
Vspart_RS12445	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
Vspart_RS12450	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
Vspart_RS12455	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
Vspart_RS12455	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
Vspart_RS12460	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
Vspart_RS12465	COG1074	ATP-dependent DNA helicase activity
Vspart_RS12470	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
Vspart_RS12475	COG0583	DNA-binding transcription factor activity
Vspart_RS12480	COG3141	response to X-ray
Vspart_RS12485	COG2171	N-acyltransferase activity
Vspart_RS12495	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
Vspart_RS12505	COG1609	Transcriptional regulator
Vspart_RS12510	COG3437	response regulator, receiver
Vspart_RS12515	COG1022	Amp-dependent synthetase and ligase
Vspart_RS12525	COG0583	DNA-binding transcription factor activity
Vspart_RS12530	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Vspart_RS12535	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
Vspart_RS12545	COG0560	Phosphoserine phosphatase
Vspart_RS12555	COG0813	purine-nucleoside phosphorylase activity
Vspart_RS12560	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
Vspart_RS12565	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
Vspart_RS12570	COG0084	hydrolase, TatD family'
Vspart_RS12580	COG3022	response to hydroperoxide
Vspart_RS12585	COG1115	amino acid carrier protein
Vspart_RS12600	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
Vspart_RS12610	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
Vspart_RS12615	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
Vspart_RS12620	COG0083	homoserine kinase activity
Vspart_RS12630	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
Vspart_RS12640	COG0745	RESPONSE REGULATOR receiver
Vspart_RS12645	COG0784	Response regulator, receiver
Vspart_RS12645	COG5002	protein histidine kinase activity
Vspart_RS12645	COG2198	Histidine kinase
Vspart_RS12650	COG2203	Gaf domain
Vspart_RS12650	COG5001	Diguanylate cyclase
Vspart_RS12650	COG4251	negative regulation of phosphorylation
Vspart_RS12650	COG3706	GGDEF domain
Vspart_RS12655	COG1242	4 iron, 4 sulfur cluster binding
Vspart_RS12660	COG0070	glutamate synthase
Vspart_RS12660	COG0069	glutamate synthase activity
Vspart_RS12660	COG0067	glutamate synthase
Vspart_RS12670	COG0070	glutamate synthase
Vspart_RS12670	COG0067	glutamate synthase
Vspart_RS12670	COG0069	glutamate synthase activity
Vspart_RS12675	COG0493	'glutamate synthase
Vspart_RS12680	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
Vspart_RS12690	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Vspart_RS12695	COG2860	membrane
Vspart_RS12700	COG0583	DNA-binding transcription factor activity
Vspart_RS12705	COG0730	response to heat
Vspart_RS12710	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
Vspart_RS12715	COG0505	Belongs to the CarA family
Vspart_RS12720	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
Vspart_RS12725	COG0494	nUDIX hydrolase
Vspart_RS12730	COG0653	protein targeting
Vspart_RS12740	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
Vspart_RS12745	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
Vspart_RS12750	COG0849	cell division
Vspart_RS12755	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
Vspart_RS12760	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
Vspart_RS12770	COG0772	Belongs to the SEDS family
Vspart_RS12775	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
Vspart_RS12785	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
Vspart_RS12790	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
Vspart_RS12795	COG0768	penicillin binding
Vspart_RS12800	COG3116	cell division
Vspart_RS12815	COG0534	Mate efflux family protein
Vspart_RS12825	COG0840	transmembrane signaling receptor activity
Vspart_RS12835	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Vspart_RS12840	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
Vspart_RS12860	COG1028	Short-chain dehydrogenase reductase Sdr
Vspart_RS12865	COG1012	belongs to the aldehyde dehydrogenase family
Vspart_RS12870	COG0028	Belongs to the TPP enzyme family
Vspart_RS12885	COG2423	ornithine cyclodeaminase activity
Vspart_RS12910	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
Vspart_RS12915	COG3107	peptidoglycan biosynthetic process
Vspart_RS12925	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
Vspart_RS12930	COG2823	Periplasmic or secreted lipoprotein
Vspart_RS12935	COG2969	positive regulation of protein catabolic process
Vspart_RS12940	COG0625	glutathione transferase activity
Vspart_RS12945	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Vspart_RS12950	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
Vspart_RS12955	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
Vspart_RS12960	COG3105	Protein conserved in bacteria
Vspart_RS12965	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Vspart_RS12970	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Vspart_RS12975	COG0335	large ribosomal subunit rRNA binding
Vspart_RS12985	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
Vspart_RS12995	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
Vspart_RS13000	COG4137	Cytochrome C assembly protein
Vspart_RS13005	COG4536	flavin adenine dinucleotide binding
Vspart_RS13015	COG2918	glutathione biosynthetic process
Vspart_RS13025	COG1238	metal cluster binding
Vspart_RS13030	COG1063	alcohol dehydrogenase
Vspart_RS13035	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
Vspart_RS13045	COG3630	sodium ion export across plasma membrane
Vspart_RS13080	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
Vspart_RS13085	COG0527	aspartate kinase activity
Vspart_RS13090	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
Vspart_RS13100	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
Vspart_RS13105	COG1546	Belongs to the CinA family
Vspart_RS13110	COG1414	Transcriptional regulator
Vspart_RS13115	COG1028	Short-chain dehydrogenase reductase Sdr
Vspart_RS13120	COG1917	Cupin 2, conserved barrel domain protein
Vspart_RS13135	COG0800	Aldolase
Vspart_RS13155	COG3842	ATPase activity
Vspart_RS13160	COG0395	ABC-type sugar transport system, permease component
Vspart_RS13165	COG1175	transmembrane transport
Vspart_RS13180	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Vspart_RS13185	COG0823	Involved in the tonB-independent uptake of proteins
Vspart_RS13190	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
Vspart_RS13195	COG3437	response regulator, receiver
Vspart_RS13195	COG0784	Response regulator, receiver
Vspart_RS13200	COG4191	Histidine kinase
Vspart_RS13200	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Vspart_RS13210	COG5297	Belongs to the glycosyl hydrolase family 6
Vspart_RS13215	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Vspart_RS13220	COG1388	LysM domain
Vspart_RS13220	COG4942	peptidase
Vspart_RS13230	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
Vspart_RS13235	COG0585	pseudouridine synthase activity
Vspart_RS13245	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
Vspart_RS13250	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
Vspart_RS13255	COG1968	undecaprenyl-diphosphatase activity
Vspart_RS13260	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
Vspart_RS13265	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
Vspart_RS13280	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
Vspart_RS13285	COG0828	Belongs to the bacterial ribosomal protein bS21 family
Vspart_RS13290	COG1610	YqeY-like protein
Vspart_RS13295	COG0358	DNA primase activity
Vspart_RS13350	COG1940	carbohydrate kinase activity
Vspart_RS13355	COG4821	SIS domain
Vspart_RS13360	COG0383	alpha-mannosidase activity
Vspart_RS13370	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Vspart_RS13370	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Vspart_RS13400	COG1368	sulfuric ester hydrolase activity
Vspart_RS13405	COG0604	alcohol dehydrogenase
Vspart_RS13460	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Vspart_RS13590	COG2204	response regulator
Vspart_RS13600	COG0840	transmembrane signaling receptor activity
Vspart_RS13610	COG2814	Major facilitator Superfamily
Vspart_RS13640	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Vspart_RS13655	COG2205	protein histidine kinase activity
Vspart_RS13660	COG0745	RESPONSE REGULATOR receiver
Vspart_RS13685	COG2217	Heavy metal translocating P-type atpase
Vspart_RS13690	COG0789	Transcriptional regulator
Vspart_RS13695	COG3344	reverse transcriptase
Vspart_RS13735	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
Vspart_RS13740	COG1349	DNA-binding transcription factor activity
Vspart_RS13745	COG0469	pyruvate kinase activity
Vspart_RS13755	COG0668	transmembrane transport
Vspart_RS13770	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
Vspart_RS13775	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
Vspart_RS13780	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
Vspart_RS13785	COG3091	SprT-like family
Vspart_RS13790	COG1385	rRNA (uridine-N3-)-methyltransferase activity
Vspart_RS13795	COG0189	ligase activity
Vspart_RS13800	COG1678	Uncharacterized ACR, COG1678
Vspart_RS13805	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
Vspart_RS13815	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
Vspart_RS13820	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
Vspart_RS13825	COG0762	integral membrane protein
Vspart_RS13830	COG1872	DUF167
Vspart_RS13840	COG3437	response regulator, receiver
Vspart_RS13855	COG2172	sigma factor antagonist activity
Vspart_RS13865	COG1366	Belongs to the anti-sigma-factor antagonist family
Vspart_RS13875	COG3040	lipid binding
Vspart_RS13915	COG3209	COG3209 Rhs family protein
Vspart_RS13935	COG3209	COG3209 Rhs family protein
Vspart_RS13970	COG3501	Rhs element vgr protein
Vspart_RS13975	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
Vspart_RS13980	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Vspart_RS13990	COG0220	tRNA (guanine-N7-)-methyltransferase activity
Vspart_RS14000	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
Vspart_RS14055	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
Vspart_RS14060	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
Vspart_RS14065	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Vspart_RS14070	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
Vspart_RS14075	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
Vspart_RS14080	COG2967	ApaG domain
Vspart_RS14085	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
Vspart_RS14095	COG3610	response to peptide
Vspart_RS14100	COG2966	Psort location CytoplasmicMembrane, score
Vspart_RS14105	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Vspart_RS14120	COG0142	geranyltranstransferase activity
Vspart_RS14130	COG0039	L-malate dehydrogenase activity
Vspart_RS14135	COG1438	arginine binding
Vspart_RS14140	COG2358	TRAP transporter, solute receptor (TAXI family
Vspart_RS14150	COG0589	response to stress
Vspart_RS14165	COG2186	Transcriptional regulator
Vspart_RS14190	COG0246	Mannitol dehydrogenase
Vspart_RS14200	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Vspart_RS14205	COG0800	Aldolase
Vspart_RS14230	COG0633	Ferredoxin
Vspart_RS14240	COG0697	spore germination
Vspart_RS14255	COG2971	BadF BadG BcrA BcrD
Vspart_RS14270	COG0395	ABC-type sugar transport system, permease component
Vspart_RS14275	COG1175	transmembrane transport
Vspart_RS14300	COG0312	modulator of DNA gyrase
Vspart_RS14305	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Vspart_RS14310	COG3164	Protein of unknown function
Vspart_RS14315	COG1530	ribonuclease E activity
Vspart_RS14320	COG0424	maF-like protein
Vspart_RS14325	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
Vspart_RS14330	COG1792	Involved in formation and maintenance of cell shape
Vspart_RS14335	COG1077	Cell shape determining protein MreB Mrl
Vspart_RS14340	COG2200	EAL domain
Vspart_RS14340	COG2199	diguanylate cyclase activity
Vspart_RS14345	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
Vspart_RS14355	COG0309	Hydrogenase expression formation protein (HypE)
Vspart_RS14365	COG0298	carbon dioxide binding
Vspart_RS14370	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
Vspart_RS14380	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
Vspart_RS14390	COG3383	formate dehydrogenase (NAD+) activity
Vspart_RS14395	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
Vspart_RS14400	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
Vspart_RS14410	COG3260	NADH ubiquinone oxidoreductase 20
Vspart_RS14415	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Vspart_RS14420	COG3261	NADH dehydrogenase
Vspart_RS14420	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
Vspart_RS14425	COG0651	ATP synthesis coupled electron transport
Vspart_RS14430	COG4237	Hydrogenase 4 membrane
Vspart_RS14435	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
Vspart_RS14440	COG0650	Formate hydrogenlyase subunit 4
Vspart_RS14445	COG0651	ATP synthesis coupled electron transport
Vspart_RS14450	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
Vspart_RS14455	COG0527	aspartate kinase activity
Vspart_RS14460	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
Vspart_RS14470	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
Vspart_RS14485	COG0629	single-stranded DNA binding
Vspart_RS14490	COG0646	methionine synthase
Vspart_RS14490	COG1410	methionine synthase
Vspart_RS14565	COG0175	sulfate reduction
Vspart_RS14570	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Vspart_RS14605	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
Vspart_RS14625	COG5433	transposase activity
Vspart_RS14635	COG5433	transposase activity
Vspart_RS14640	COG0583	DNA-binding transcription factor activity
Vspart_RS14645	COG1942	4-Oxalocrotonate Tautomerase
Vspart_RS14650	COG0697	spore germination
Vspart_RS14695	COG0693	protein deglycase activity
Vspart_RS14730	COG0735	belongs to the Fur family
Vspart_RS14750	COG0305	Participates in initiation and elongation during chromosome replication
Vspart_RS14760	COG0359	binds to the 23S rRNA
Vspart_RS14765	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
Vspart_RS14770	COG2965	DNA replication, synthesis of RNA primer
Vspart_RS14775	COG0360	Binds together with S18 to 16S ribosomal RNA
Vspart_RS14795	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Vspart_RS14800	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Vspart_RS14805	COG0049	tRNA binding
Vspart_RS14825	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
Vspart_RS14830	COG2964	Protein conserved in bacteria
Vspart_RS14835	COG0545	Peptidyl-prolyl cis-trans isomerase
Vspart_RS14850	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
Vspart_RS14855	COG0330	HflC and HflK could
Vspart_RS14860	COG0330	HflC and HflK could
Vspart_RS14865	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
Vspart_RS14870	COG1923	regulation of RNA biosynthetic process
Vspart_RS14875	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
Vspart_RS14880	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
Vspart_RS14885	COG0860	N-Acetylmuramoyl-L-alanine amidase
Vspart_RS14890	COG0802	atpase or kinase
Vspart_RS14895	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
Vspart_RS14935	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
Vspart_RS14940	COG1162	GTPase activity
Vspart_RS14945	COG0688	phosphatidylethanolamine metabolic process
Vspart_RS14950	COG0471	metal ion transport
Vspart_RS14960	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
Vspart_RS14965	COG4942	peptidase
Vspart_RS14975	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
Vspart_RS14980	COG2816	NAD+ diphosphatase activity
Vspart_RS14985	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
Vspart_RS14990	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
Vspart_RS14995	COG0085	RNA polymerase activity
Vspart_RS15005	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
Vspart_RS15010	COG0081	regulation of translation
Vspart_RS15015	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
Vspart_RS15020	COG0250	Participates in transcription elongation, termination and antitermination
Vspart_RS15025	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
Vspart_RS15030	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Vspart_RS15055	COG1072	(Pantothenic acid kinase))
Vspart_RS15065	COG0812	UDP-N-acetylmuramate dehydrogenase activity
Vspart_RS15075	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Vspart_RS15090	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
Vspart_RS15105	COG3118	belongs to the thioredoxin family
Vspart_RS15110	COG0513	Belongs to the DEAD box helicase family
Vspart_RS15115	COG0248	Ppx GppA phosphatase
Vspart_RS15120	COG2205	protein histidine kinase activity
Vspart_RS15120	COG0784	Response regulator, receiver
Vspart_RS15120	COG2198	Histidine kinase
Vspart_RS15125	COG2188	Transcriptional regulator
Vspart_RS15140	COG2814	Major facilitator Superfamily
Vspart_RS15155	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Vspart_RS15160	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
Vspart_RS15165	COG0511	ligase activity, forming carbon-carbon bonds
Vspart_RS15170	COG0439	Biotin carboxylase
Vspart_RS15175	COG2264	protein methyltransferase activity
Vspart_RS15195	COG1028	Short-chain dehydrogenase reductase Sdr
Vspart_RS15200	COG1733	regulation of RNA biosynthetic process
Vspart_RS15205	COG0840	transmembrane signaling receptor activity
Vspart_RS15225	COG0138	bifunctional purine biosynthesis protein purh
Vspart_RS15230	COG0151	Belongs to the GarS family
Vspart_RS15240	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Vspart_RS15245	COG2183	response to ionizing radiation
Vspart_RS15255	COG0596	Alpha beta hydrolase
Vspart_RS15260	COG1040	competence protein
Vspart_RS15265	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
Vspart_RS15265	COG0316	Belongs to the HesB IscA family
Vspart_RS15270	COG0494	nUDIX hydrolase
Vspart_RS15275	COG1218	3'(2'),5'-bisphosphate nucleotidase
Vspart_RS15285	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
Vspart_RS15290	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
Vspart_RS15295	COG3156	type II secretion system protein K
Vspart_RS15300	COG4795	General secretion pathway protein
Vspart_RS15305	COG2165	general secretion pathway protein
Vspart_RS15310	COG2165	general secretion pathway protein
Vspart_RS15315	COG2165	general secretion pathway protein
Vspart_RS15320	COG1459	type II secretion system
Vspart_RS15325	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Vspart_RS15335	COG3031	protein transport across the cell outer membrane
Vspart_RS15340	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
Vspart_RS15345	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
Vspart_RS15350	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
Vspart_RS15360	COG0456	acetyltransferase
Vspart_RS15365	COG1490	D-aminoacyl-tRNA deacylase activity
Vspart_RS15370	COG1295	ribonuclease BN
Vspart_RS15380	COG0174	glutamine synthetase
Vspart_RS15385	COG3852	Histidine kinase
Vspart_RS15390	COG2204	response regulator
Vspart_RS15450	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
Vspart_RS15455	COG4206	TonB-dependent receptor
Vspart_RS15480	COG0477	Major facilitator Superfamily
Vspart_RS15495	COG3501	Rhs element vgr protein
Vspart_RS15580	COG2084	Dehydrogenase
Vspart_RS15585	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Vspart_RS15590	COG1349	DNA-binding transcription factor activity
Vspart_RS15620	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Vspart_RS15625	COG0583	DNA-binding transcription factor activity
Vspart_RS15640	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Vspart_RS15645	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
Vspart_RS15650	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
Vspart_RS15655	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
Vspart_RS15665	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
Vspart_RS15670	COG3161	chorismate lyase activity
Vspart_RS15680	COG0705	Rhomboid family
Vspart_RS15695	COG2177	Part of the ABC transporter FtsEX involved in
Vspart_RS15700	COG2884	Cell division ATP-binding protein ftsE
Vspart_RS15705	COG0552	protein localization to endoplasmic reticulum
Vspart_RS15710	COG0742	ribosomal rna small subunit methyltransferase
Vspart_RS15715	COG2095	MarC family integral membrane protein
Vspart_RS15740	COG0783	Belongs to the Dps family
Vspart_RS15745	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
Vspart_RS15750	COG1280	lysine exporter protein (LysE YggA)
Vspart_RS15755	COG2267	carboxylic ester hydrolase activity
Vspart_RS15760	COG0561	phosphatase activity
Vspart_RS15765	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Vspart_RS15775	COG2977	Belongs to the P-Pant transferase superfamily
Vspart_RS15795	COG1011	Hydrolase
Vspart_RS15800	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
Vspart_RS15815	COG0019	diaminopimelate decarboxylase activity
Vspart_RS15845	COG2959	enzyme of heme biosynthesis
Vspart_RS15850	COG3071	HemY protein
Vspart_RS15865	COG3078	GTPase activator activity
Vspart_RS15880	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Vspart_RS15880	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Vspart_RS15890	COG0084	hydrolase, TatD family'
Vspart_RS15895	COG0583	DNA-binding transcription factor activity
Vspart_RS15900	COG2249	NAD(P)H dehydrogenase (quinone) activity
Vspart_RS15905	COG0805	protein transport
Vspart_RS15910	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Vspart_RS15915	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Vspart_RS15920	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
Vspart_RS15925	COG3165	ubiquinone biosynthetic process from chorismate
Vspart_RS15930	COG2226	methyltransferase
Vspart_RS15935	COG1322	Protein conserved in bacteria
Vspart_RS15965	COG2160	L-arabinose isomerase activity
Vspart_RS15975	COG1069	ribulokinase activity
Vspart_RS15980	COG1879	ABC-type sugar transport system periplasmic component
Vspart_RS15985	COG1129	ABC transporter
Vspart_RS15990	COG1172	Belongs to the binding-protein-dependent transport system permease family
Vspart_RS15995	COG2329	Antibiotic biosynthesis monooxygenase
Vspart_RS16035	COG0583	DNA-binding transcription factor activity
Vspart_RS16050	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Vspart_RS16055	COG0028	Belongs to the TPP enzyme family
Vspart_RS16060	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
Vspart_RS16060	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
Vspart_RS16095	COG2378	regulation of single-species biofilm formation
Vspart_RS16195	COG0702	epimerase
Vspart_RS16205	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
Vspart_RS16235	COG1468	defense response to virus
Vspart_RS16235	COG1518	maintenance of DNA repeat elements
Vspart_RS16280	COG2188	Transcriptional regulator
Vspart_RS16285	COG1070	Carbohydrate kinase
Vspart_RS16290	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Vspart_RS16365	COG2081	HI0933 family
Vspart_RS16375	COG1528	Iron-storage protein
Vspart_RS16395	COG0742	ribosomal rna small subunit methyltransferase
Vspart_RS16400	COG1522	sequence-specific DNA binding
Vspart_RS16410	COG0006	proline dipeptidase activity
Vspart_RS16440	COG4175	Glycine betaine
Vspart_RS16445	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
Vspart_RS16450	COG2022	thiamine diphosphate biosynthetic process
Vspart_RS16455	COG2104	thiamine diphosphate biosynthetic process
Vspart_RS16460	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
Vspart_RS16465	COG0352	thiamine-phosphate diphosphorylase activity
Vspart_RS16480	COG3940	Belongs to the glycosyl hydrolase 43 family
Vspart_RS16485	COG2211	Major facilitator Superfamily
Vspart_RS16525	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
Vspart_RS16530	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
Vspart_RS16535	COG1739	Uncharacterized protein family UPF0029
Vspart_RS16555	COG0355	proton-transporting ATP synthase activity, rotational mechanism
Vspart_RS16560	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
Vspart_RS16565	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
Vspart_RS16570	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
Vspart_RS16575	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Vspart_RS16580	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
Vspart_RS16590	COG0356	it plays a direct role in the translocation of protons across the membrane
Vspart_RS16600	COG1475	DNA binding
Vspart_RS16605	COG1192	Involved in chromosome partitioning
Vspart_RS16615	COG0445	tRNA wobble uridine modification
Vspart_RS16620	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
Vspart_RS16660	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
Vspart_RS16665	COG0706	membrane insertase activity
Vspart_RS16675	COG0594	ribonuclease P activity
Vspart_RS16685	COG1126	abc transporter atp-binding protein
Vspart_RS16705	COG1444	tRNA N-acetyltransferase activity
Vspart_RS16730	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Vspart_RS16740	COG1262	PFAM Formylglycine-generating sulfatase enzyme
Vspart_RS16770	COG3722	fumarate hydratase activity
Vspart_RS16780	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
Vspart_RS16780	COG2213	PTS system mannitol-specific
Vspart_RS16785	COG3085	chromosome segregation
Vspart_RS16795	COG2259	Doxx family
Vspart_RS16805	COG0840	transmembrane signaling receptor activity
Vspart_RS16830	COG2272	Belongs to the type-B carboxylesterase lipase family
Vspart_RS16845	COG0583	DNA-binding transcription factor activity
Vspart_RS16855	COG1940	carbohydrate kinase activity
Vspart_RS16860	COG0191	fructose-bisphosphate aldolase activity
Vspart_RS16865	COG0191	fructose-bisphosphate aldolase activity
Vspart_RS16870	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Vspart_RS16870	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Vspart_RS16870	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
Vspart_RS16875	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
Vspart_RS16875	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Vspart_RS16875	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Vspart_RS16885	COG3711	transcriptional antiterminator
Vspart_RS16900	COG1794	racemase activity, acting on amino acids and derivatives
Vspart_RS16915	COG2873	o-acetylhomoserine
Vspart_RS16925	COG1280	lysine exporter protein (LysE YggA)
Vspart_RS16930	COG3693	PFAM glycoside hydrolase, family 10
Vspart_RS16930	COG3509	depolymerase
Vspart_RS16975	COG0456	acetyltransferase
Vspart_RS16975	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
Vspart_RS17070	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Vspart_RS17085	COG0151	Belongs to the GarS family
Vspart_RS17145	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
Vspart_RS17150	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Vspart_RS17155	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Vspart_RS17160	COG1120	ATPase activity
Vspart_RS17170	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
Vspart_RS17175	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
Vspart_RS17180	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
Vspart_RS17185	COG0247	lactate metabolic process
Vspart_RS17195	COG1609	Transcriptional regulator
Vspart_RS17300	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Vspart_RS17305	COG1063	alcohol dehydrogenase
Vspart_RS17310	COG2186	Transcriptional regulator
Vspart_RS17315	COG4948	Mandelate Racemase Muconate Lactonizing
Vspart_RS17320	COG0246	Mannitol dehydrogenase
Vspart_RS17385	COG1468	defense response to virus
Vspart_RS17385	COG1518	maintenance of DNA repeat elements
Vspart_RS17435	COG1605	Chorismate mutase
Vspart_RS17450	COG1139	Iron-sulfur cluster binding protein
Vspart_RS17460	COG1620	l-lactate permease
Vspart_RS17465	COG0583	DNA-binding transcription factor activity
Vspart_RS17475	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
Vspart_RS17485	COG0471	metal ion transport
Vspart_RS17490	COG1051	belongs to the nudix hydrolase family
Vspart_RS17535	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Vspart_RS17550	COG0346	lactoylglutathione lyase activity
Vspart_RS17575	COG2814	Major facilitator Superfamily
Vspart_RS17600	COG2771	luxR family
Vspart_RS17615	COG2207	Transcriptional regulator
Vspart_RS17620	COG4773	Receptor
Vspart_RS17635	COG2723	6-phospho-beta-galactosidase activity
Vspart_RS17640	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Vspart_RS17640	COG1263	PTS System
Vspart_RS17645	COG3265	gluconokinase activity
Vspart_RS17650	COG1609	Transcriptional regulator
Vspart_RS17660	COG4399	Belongs to the UPF0754 family
Vspart_RS17665	COG1132	(ABC) transporter
Vspart_RS17680	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
Vspart_RS17690	COG3706	GGDEF domain
Vspart_RS17700	COG3272	Protein of unknown function (DUF1722)
Vspart_RS17705	COG0789	Transcriptional regulator
Vspart_RS17710	COG0415	Belongs to the DNA photolyase family
Vspart_RS17715	COG1388	LysM domain
Vspart_RS17715	COG1376	ErfK ybiS ycfS ynhG family protein
Vspart_RS17725	COG0513	Belongs to the DEAD box helicase family
Vspart_RS17730	COG0840	transmembrane signaling receptor activity
Vspart_RS17740	COG0573	inorganic phosphate transmembrane transporter activity
Vspart_RS17745	COG0581	inorganic phosphate transmembrane transporter activity
Vspart_RS17750	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
Vspart_RS17765	COG0739	heme binding
Vspart_RS17770	COG5001	Diguanylate cyclase
Vspart_RS17780	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
Vspart_RS17785	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
Vspart_RS17790	COG2814	Major facilitator Superfamily
Vspart_RS17795	COG0583	DNA-binding transcription factor activity
Vspart_RS17800	COG0667	Aldo Keto reductase
Vspart_RS17805	COG0583	DNA-binding transcription factor activity
Vspart_RS17810	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Vspart_RS17830	COG0179	Fumarylacetoacetate (FAA) hydrolase
Vspart_RS17835	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
Vspart_RS17850	COG2190	(PTS) system
Vspart_RS17850	COG1263	PTS System
Vspart_RS17850	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Vspart_RS17855	COG1263	PTS System
Vspart_RS17855	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Vspart_RS17855	COG2190	(PTS) system
Vspart_RS17860	COG3711	transcriptional antiterminator
Vspart_RS17865	COG2723	6-phospho-beta-galactosidase activity
Vspart_RS17880	COG2095	MarC family integral membrane protein
Vspart_RS17895	COG0384	phenazine biosynthesis protein PhzF
Vspart_RS17910	COG0604	alcohol dehydrogenase
Vspart_RS17935	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
Vspart_RS17940	COG2267	carboxylic ester hydrolase activity
Vspart_RS17945	COG1979	alcohol dehydrogenase
Vspart_RS17950	COG1357	PFAM Pentapeptide repeats (8 copies)
Vspart_RS18020	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
Vspart_RS18025	COG2194	sulfuric ester hydrolase activity
Vspart_RS18030	COG5002	protein histidine kinase activity
Vspart_RS18035	COG0745	RESPONSE REGULATOR receiver
Vspart_RS18050	COG0534	Mate efflux family protein
Vspart_RS18065	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Vspart_RS18080	COG0784	Response regulator, receiver
Vspart_RS18080	COG2205	protein histidine kinase activity
Vspart_RS18080	COG5002	protein histidine kinase activity
Vspart_RS18090	COG1765	OsmC-like protein
Vspart_RS18100	COG2354	Protein conserved in bacteria
Vspart_RS18125	COG0418	dihydroorotase activity
Vspart_RS18160	COG0840	transmembrane signaling receptor activity
Vspart_RS18165	COG0646	methionine synthase
Vspart_RS18165	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
Vspart_RS18175	COG0840	transmembrane signaling receptor activity
Vspart_RS18185	COG2814	Major facilitator Superfamily
Vspart_RS18190	COG1522	sequence-specific DNA binding
Vspart_RS18220	COG0456	acetyltransferase
Vspart_RS18230	COG0189	ligase activity
Vspart_RS18230	COG0569	domain protein
Vspart_RS18250	COG0363	glucosamine-6-phosphate deaminase activity
Vspart_RS18255	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
Vspart_RS18260	COG3437	response regulator, receiver
Vspart_RS18275	COG2991	Protein conserved in bacteria
Vspart_RS18280	COG0673	inositol 2-dehydrogenase activity
Vspart_RS18295	COG1064	alcohol dehydrogenase
Vspart_RS18300	COG4305	rare lipoprotein A
Vspart_RS18320	COG3724	N-succinylarginine dihydrolase activity
Vspart_RS18325	COG2988	succinylglutamate desuccinylase activity
Vspart_RS18330	COG3706	GGDEF domain
Vspart_RS18335	COG5002	protein histidine kinase activity
Vspart_RS18370	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Vspart_RS18380	COG0156	8-amino-7-oxononanoate synthase activity
Vspart_RS18385	COG2205	protein histidine kinase activity
Vspart_RS18385	COG0784	Response regulator, receiver
Vspart_RS18390	COG3501	Rhs element vgr protein
Vspart_RS18430	COG1335	isochorismatase
Vspart_RS18435	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Vspart_RS18435	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Vspart_RS18440	COG0509	glycine decarboxylation via glycine cleavage system
Vspart_RS18450	COG0404	The glycine cleavage system catalyzes the degradation of glycine
Vspart_RS18460	COG3300	MHYT domain
Vspart_RS18460	COG5001	Diguanylate cyclase
Vspart_RS18475	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
Vspart_RS18480	COG0840	transmembrane signaling receptor activity
Vspart_RS18485	COG1609	Transcriptional regulator
Vspart_RS18505	COG2723	6-phospho-beta-galactosidase activity
Vspart_RS18510	COG3842	ATPase activity
Vspart_RS18515	COG3459	Glycosyltransferase 36 associated
Vspart_RS18525	COG1609	Transcriptional regulator
Vspart_RS18530	COG5297	Belongs to the glycosyl hydrolase family 6
Vspart_RS18530	COG2273	Hydrolase Family 16
Vspart_RS18565	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
Vspart_RS18575	COG4181	ATPase activity
Vspart_RS18585	COG2095	MarC family integral membrane protein
Vspart_RS18595	COG5297	Belongs to the glycosyl hydrolase family 6
Vspart_RS18595	COG2273	Hydrolase Family 16
Vspart_RS18625	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Vspart_RS18630	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
Vspart_RS18650	COG2425	protein containing a von Willebrand factor type A (vWA) domain
Vspart_RS18655	COG3713	MltA-interacting MipA family protein
Vspart_RS18660	COG1584	GPR1 FUN34 yaaH family protein
Vspart_RS18665	COG0625	glutathione transferase activity
Vspart_RS18695	COG0494	nUDIX hydrolase
Vspart_RS18700	COG0678	peroxiredoxin activity
Vspart_RS18710	COG3132	Protein of unknown function, DUF480
Vspart_RS18720	COG1879	ABC-type sugar transport system periplasmic component
Vspart_RS18725	COG0784	Response regulator, receiver
Vspart_RS18725	COG5002	protein histidine kinase activity
Vspart_RS18735	COG1492	cobalamin metabolic process
Vspart_RS18750	COG1289	transmembrane transporter activity
Vspart_RS18755	COG0210	DNA helicase
Vspart_RS18760	COG1803	Methylglyoxal synthase
Vspart_RS18765	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
Vspart_RS18780	COG0183	Belongs to the thiolase family
Vspart_RS18795	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
Vspart_RS18800	COG0523	cobalamin synthesis protein
Vspart_RS18810	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
Vspart_RS18825	COG0513	Belongs to the DEAD box helicase family
Vspart_RS18830	COG0840	transmembrane signaling receptor activity
Vspart_RS18835	COG2723	6-phospho-beta-galactosidase activity
Vspart_RS18855	COG3300	MHYT domain
Vspart_RS18855	COG5001	Diguanylate cyclase
Vspart_RS18860	COG2816	NAD+ diphosphatase activity
Vspart_RS18865	COG0488	(ABC) transporter
Vspart_RS18870	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
Vspart_RS18880	COG4943	cyclic-guanylate-specific phosphodiesterase activity
Vspart_RS18895	COG3507	Belongs to the glycosyl hydrolase 43 family
Vspart_RS18900	COG1203	CRISPR-associated helicase, Cas3
Vspart_RS18930	COG1518	maintenance of DNA repeat elements
Vspart_RS18935	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
Vspart_RS18940	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Vspart_RS18940	COG3153	acetyltransferase
Vspart_RS18950	COG0513	Belongs to the DEAD box helicase family
Vspart_RS18955	COG0513	Belongs to the DEAD box helicase family
Vspart_RS18970	COG0243	molybdopterin cofactor binding
Vspart_RS18985	COG3634	alkyl hydroperoxide reductase activity
Vspart_RS18995	COG1063	alcohol dehydrogenase
Vspart_RS19025	COG1328	CTP reductase activity
Vspart_RS19030	COG0602	queuosine metabolic process
Vspart_RS19040	COG1538	Outer membrane efflux protein
Vspart_RS19050	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Vspart_RS19065	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
Vspart_RS19075	COG0402	S-adenosylhomocysteine deaminase activity
Vspart_RS19080	COG2351	hydroxyisourate hydrolase activity
Vspart_RS19090	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
Vspart_RS19090	COG3608	succinylglutamate desuccinylase aspartoacylase
Vspart_RS19120	COG1129	ABC transporter
Vspart_RS19125	COG1309	transcriptional regulator
Vspart_RS19140	COG3300	MHYT domain
Vspart_RS19140	COG5001	Diguanylate cyclase
Vspart_RS19155	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
Vspart_RS19170	COG2207	Transcriptional regulator
Vspart_RS19180	COG1960	acyl-CoA dehydrogenase activity
Vspart_RS19210	COG2192	nodulation
Vspart_RS19230	COG3706	GGDEF domain
Vspart_RS19245	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
Vspart_RS19250	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
Vspart_RS19280	COG0023	Translation Initiation Factor
Vspart_RS19305	COG0045	succinate-CoA ligase (ADP-forming) activity
Vspart_RS19305	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Vspart_RS19305	COG1042	CoA-binding domain protein
Vspart_RS19310	COG0583	DNA-binding transcription factor activity
Vspart_RS19315	COG4533	DNA binding
Vspart_RS19320	COG2050	protein possibly involved in aromatic compounds catabolism
Vspart_RS19325	COG2824	Alkylphosphonate utilization operon protein PhnA
Vspart_RS19335	COG0737	Belongs to the 5'-nucleotidase family
Vspart_RS19340	COG3593	DNA synthesis involved in DNA repair
Vspart_RS19345	COG0583	DNA-binding transcription factor activity
Vspart_RS19350	COG2116	formate transmembrane transporter activity
Vspart_RS19355	COG2353	YceI-like domain
Vspart_RS19360	COG3038	cytochrome b561
Vspart_RS19375	COG4172	Belongs to the ABC transporter superfamily
Vspart_RS19380	COG4239	(ABC) transporter, permease
Vspart_RS19385	COG4174	ABC transporter (Permease)
Vspart_RS19390	COG4166	transmembrane transport
Vspart_RS19395	COG1051	belongs to the nudix hydrolase family
Vspart_RS19410	COG1011	Hydrolase
Vspart_RS19420	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
Vspart_RS19430	COG0302	gtp cyclohydrolase
Vspart_RS19440	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
Vspart_RS19445	COG2897	thiosulfate sulfurtransferase activity
Vspart_RS19460	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
Vspart_RS19470	COG0545	Peptidyl-prolyl cis-trans isomerase
Vspart_RS19475	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Vspart_RS19495	COG0291	Belongs to the bacterial ribosomal protein bL35 family
Vspart_RS19650	COG1396	sequence-specific DNA binding
Vspart_RS19660	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
Vspart_RS19665	COG2515	1-aminocyclopropane-1-carboxylate deaminase
Vspart_RS19670	COG1522	sequence-specific DNA binding
Vspart_RS19685	COG1121	(ABC) transporter
Vspart_RS19690	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Vspart_RS19695	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Vspart_RS19700	COG2985	domain, Protein
Vspart_RS19705	COG1609	Transcriptional regulator
Vspart_RS19710	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Vspart_RS19715	COG1879	ABC-type sugar transport system periplasmic component
Vspart_RS19720	COG1172	Belongs to the binding-protein-dependent transport system permease family
Vspart_RS19730	COG1869	D-ribose catabolic process
Vspart_RS19740	COG3409	Peptidoglycan-binding domain 1 protein
Vspart_RS19740	COG3757	hydrolase, family 25
Vspart_RS19795	COG2828	Protein conserved in bacteria
Vspart_RS19805	COG0642	Histidine kinase
Vspart_RS19810	COG0745	RESPONSE REGULATOR receiver
Vspart_RS19825	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
Vspart_RS19830	COG0626	cystathionine gamma-synthase activity
Vspart_RS19850	COG1609	Transcriptional regulator
Vspart_RS19860	COG1105	Belongs to the carbohydrate kinase PfkB family
Vspart_RS19865	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
Vspart_RS19865	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Vspart_RS19865	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Vspart_RS19870	COG3693	PFAM glycoside hydrolase, family 10
Vspart_RS19880	COG1929	Belongs to the glycerate kinase type-1 family
Vspart_RS19895	COG1902	pentaerythritol trinitrate reductase activity
Vspart_RS19895	COG0446	pyridine nucleotide-disulphide oxidoreductase
Vspart_RS19905	COG4251	negative regulation of phosphorylation
Vspart_RS19920	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
Vspart_RS19925	COG3104	oligopeptide transport
Vspart_RS19930	COG1070	Carbohydrate kinase
Vspart_RS19935	COG1609	Transcriptional regulator
Vspart_RS19935	COG2207	Transcriptional regulator
Vspart_RS19940	COG0477	Major facilitator Superfamily
Vspart_RS19940	COG2814	Major facilitator Superfamily
Vspart_RS19945	COG2115	Belongs to the xylose isomerase family
Vspart_RS19980	COG0840	transmembrane signaling receptor activity
Vspart_RS20020	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
Vspart_RS20040	COG1737	Transcriptional regulator
Vspart_RS20045	COG1126	abc transporter atp-binding protein
Vspart_RS20050	COG0765	amino acid transport
Vspart_RS20055	COG0765	amino acid transport
Vspart_RS20060	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Vspart_RS20075	COG1953	Uracil, thiamine, allantoin
Vspart_RS20095	COG3940	Belongs to the glycosyl hydrolase 43 family
Vspart_RS20125	COG3209	COG3209 Rhs family protein
Vspart_RS20135	COG3210	domain, Protein
Vspart_RS20145	COG0419	ATPase involved in DNA repair
Vspart_RS20165	COG0454	-acetyltransferase
Vspart_RS20195	COG3210	domain, Protein
Vspart_RS20200	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Vspart_RS20205	COG0659	secondary active sulfate transmembrane transporter activity
Vspart_RS20250	COG2017	converts alpha-aldose to the beta-anomer
Vspart_RS20270	COG1566	PFAM secretion protein HlyD family protein
Vspart_RS20275	COG1289	transmembrane transporter activity
Vspart_RS20290	COG2211	Major facilitator Superfamily
Vspart_RS20295	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
Vspart_RS20305	COG3477	response to acidic pH
Vspart_RS20310	COG1012	belongs to the aldehyde dehydrogenase family
Vspart_RS20315	COG3284	Transcriptional regulator
Vspart_RS20320	COG0077	Prephenate dehydratase
Vspart_RS20320	COG1605	Chorismate mutase
Vspart_RS20330	COG1349	DNA-binding transcription factor activity
Vspart_RS20335	COG0584	glycerophosphoryl diester phosphodiesterase
Vspart_RS20345	COG1175	transmembrane transport
Vspart_RS20350	COG0395	ABC-type sugar transport system, permease component
Vspart_RS20355	COG3842	ATPase activity
Vspart_RS20365	COG0681	Belongs to the peptidase S26 family
Vspart_RS20380	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Vspart_RS20385	COG0242	peptide deformylase activity
Vspart_RS20390	COG4115	mRNA cleavage
Vspart_RS20425	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
Vspart_RS20475	COG1942	4-Oxalocrotonate Tautomerase
Vspart_RS20510	COG3730	PTS system glucitol sorbitol-specific
Vspart_RS20515	COG1349	DNA-binding transcription factor activity
Vspart_RS20520	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
Vspart_RS20525	COG1028	Short-chain dehydrogenase reductase Sdr
Vspart_RS20530	COG3731	PTS system glucitol sorbitol-specific IIA component
Vspart_RS20540	COG3730	PTS system glucitol sorbitol-specific
Vspart_RS20555	COG0840	transmembrane signaling receptor activity
Vspart_RS20580	COG0076	glutamate decarboxylase activity
Vspart_RS20590	COG2207	Transcriptional regulator
Vspart_RS20600	COG0747	negative chemotaxis
Vspart_RS20610	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Vspart_RS20615	COG0444	Belongs to the ABC transporter superfamily
Vspart_RS20620	COG4608	Belongs to the ABC transporter superfamily
Vspart_RS20630	COG2267	carboxylic ester hydrolase activity
Vspart_RS20635	COG1028	Short-chain dehydrogenase reductase Sdr
Vspart_RS20645	COG1278	Cold shock
Vspart_RS20660	COG2194	sulfuric ester hydrolase activity
Vspart_RS20690	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
Vspart_RS20695	COG3604	Transcriptional regulator
Vspart_RS20705	COG4106	trans-aconitate 2-methyltransferase activity
Vspart_RS20710	COG1280	lysine exporter protein (LysE YggA)
Vspart_RS20745	COG1846	Transcriptional regulator
Vspart_RS20750	COG2313	pseudouridylate synthase activity
Vspart_RS20755	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Vspart_RS20755	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Vspart_RS20775	COG0546	phosphoglycolate phosphatase activity
Vspart_RS20805	COG0515	serine threonine protein kinase
Vspart_RS20840	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
Vspart_RS20845	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
Vspart_RS20850	COG2204	response regulator
Vspart_RS20900	COG0516	GMP reductase activity
Vspart_RS20910	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
Vspart_RS20910	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
Vspart_RS20915	COG3290	protein histidine kinase activity
Vspart_RS20915	COG3829	transcription factor binding
Vspart_RS20920	COG2205	protein histidine kinase activity
Vspart_RS20920	COG4999	Histidine kinase
Vspart_RS20920	COG3437	response regulator, receiver
Vspart_RS20920	COG3850	Histidine kinase
Vspart_RS20930	COG3036	rescue of stalled ribosome
Vspart_RS20935	COG1278	Cold shock
Vspart_RS20940	COG3604	Transcriptional regulator
Vspart_RS20950	COG2195	Cleaves the N-terminal amino acid of tripeptides
Vspart_RS20960	COG1448	Aminotransferase
Vspart_RS20975	COG0714	Associated with various cellular activities
Vspart_RS21010	COG3250	beta-galactosidase activity
Vspart_RS21015	COG2211	Major facilitator Superfamily
Vspart_RS21020	COG1522	sequence-specific DNA binding
Vspart_RS21040	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Vspart_RS21045	COG0077	Prephenate dehydratase
Vspart_RS21060	COG1280	lysine exporter protein (LysE YggA)
Vspart_RS21070	COG4598	ABC transporter
Vspart_RS21075	COG4160	amino acid transport
Vspart_RS21080	COG4215	(ABC) transporter
Vspart_RS21095	COG0840	transmembrane signaling receptor activity
Vspart_RS21100	COG0840	transmembrane signaling receptor activity
Vspart_RS21110	COG3118	belongs to the thioredoxin family
Vspart_RS21115	COG1764	response to oxidative stress
Vspart_RS21120	COG1846	Transcriptional regulator
Vspart_RS21130	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
Vspart_RS21145	COG4104	PAAR repeat-containing protein
Vspart_RS21150	COG3530	Putative quorum-sensing-regulated virulence factor
Vspart_RS21155	COG1486	melibiose metabolic process
Vspart_RS21160	COG0583	DNA-binding transcription factor activity
Vspart_RS21170	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Vspart_RS21175	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Vspart_RS21185	COG0784	Response regulator, receiver
Vspart_RS21185	COG0835	chemotaxis
Vspart_RS21215	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
Vspart_RS21225	COG0668	transmembrane transport
Vspart_RS21235	COG1741	Belongs to the pirin family
Vspart_RS21240	COG0840	transmembrane signaling receptor activity
Vspart_RS21250	COG0252	asparaginase activity
Vspart_RS21255	COG0527	aspartate kinase activity
Vspart_RS21260	COG0662	Cupin 2, conserved barrel domain protein
Vspart_RS21265	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
Vspart_RS21270	COG0456	acetyltransferase
Vspart_RS21275	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Vspart_RS21290	COG0642	Histidine kinase
Vspart_RS21295	COG0745	RESPONSE REGULATOR receiver
Vspart_RS21310	COG1022	Amp-dependent synthetase and ligase
Vspart_RS21330	COG1785	Belongs to the alkaline phosphatase family
Vspart_RS21345	COG0583	DNA-binding transcription factor activity
Vspart_RS21365	COG4533	DNA binding
Vspart_RS21380	COG2211	Major facilitator Superfamily
Vspart_RS21400	COG1914	H( )-stimulated, divalent metal cation uptake system
Vspart_RS21405	COG1321	iron dependent repressor
Vspart_RS21495	COG3501	Rhs element vgr protein
Vspart_RS21510	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Vspart_RS21510	COG4191	Histidine kinase
Vspart_RS21515	COG4191	Histidine kinase
Vspart_RS21515	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Vspart_RS21520	COG3437	response regulator, receiver
Vspart_RS21520	COG0784	Response regulator, receiver
Vspart_RS21525	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
Vspart_RS21530	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
Vspart_RS21535	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
Vspart_RS21540	COG3338	carbonate dehydratase activity
Vspart_RS21555	COG4175	Glycine betaine
Vspart_RS21560	COG4176	ABC-type proline glycine betaine transport system permease component
Vspart_RS21565	COG2113	Glycine betaine
Vspart_RS21570	COG2239	Acts as a magnesium transporter
Vspart_RS21580	COG0583	DNA-binding transcription factor activity
Vspart_RS21590	COG0511	ligase activity, forming carbon-carbon bonds
Vspart_RS21600	COG1984	allophanate hydrolase subunit 2
Vspart_RS21605	COG2818	Glycosylase
Vspart_RS21615	COG5001	Diguanylate cyclase
Vspart_RS21615	COG3300	MHYT domain
Vspart_RS21620	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
Vspart_RS21630	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Vspart_RS21635	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
Vspart_RS21640	COG0534	Mate efflux family protein
Vspart_RS21645	COG1067	ATP-dependent peptidase activity
Vspart_RS21660	COG0110	maltose O-acetyltransferase activity
Vspart_RS21670	COG5520	Belongs to the glycosyl hydrolase 30 family
Vspart_RS21680	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
Vspart_RS21685	COG0163	prenyltransferase activity
Vspart_RS21710	COG0277	FAD linked oxidase domain protein
Vspart_RS21715	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
Vspart_RS21720	COG1640	4-alpha-glucanotransferase
Vspart_RS21725	COG0058	SHG alpha-glucan phosphorylase activity
Vspart_RS21730	COG0109	protoheme IX farnesyltransferase activity
Vspart_RS21735	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
Vspart_RS21740	COG1845	cytochrome c oxidase, subunit III
Vspart_RS21745	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
Vspart_RS21750	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
Vspart_RS21755	COG0217	transcriptional regulatory protein