locus-tag	class	description
IM698_RS00015	COG0646	methionine synthase
IM698_RS00015	COG1410	methionine synthase
IM698_RS00020	COG0527	aspartate kinase activity
IM698_RS00025	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
IM698_RS00040	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
IM698_RS00050	COG2197	response regulator
IM698_RS00055	COG0629	single-stranded DNA binding
IM698_RS00060	COG2200	EAL domain
IM698_RS00060	COG2199	diguanylate cyclase activity
IM698_RS00085	COG3267	Type II secretory pathway component ExeA
IM698_RS00085	COG3409	Peptidoglycan-binding domain 1 protein
IM698_RS00095	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IM698_RS00100	COG1459	type II secretion system
IM698_RS00110	COG2165	general secretion pathway protein
IM698_RS00115	COG2165	general secretion pathway protein
IM698_RS00145	COG1077	Cell shape determining protein MreB Mrl
IM698_RS00150	COG1792	Involved in formation and maintenance of cell shape
IM698_RS00155	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
IM698_RS00160	COG0424	maF-like protein
IM698_RS00175	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IM698_RS00180	COG0312	modulator of DNA gyrase
IM698_RS00185	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
IM698_RS00190	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
IM698_RS00205	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IM698_RS00210	COG0589	response to stress
IM698_RS00225	COG1438	arginine binding
IM698_RS00230	COG0039	L-malate dehydrogenase activity
IM698_RS00240	COG0142	geranyltranstransferase activity
IM698_RS00245	COG0261	This protein binds to 23S rRNA in the presence of protein L20
IM698_RS00250	COG0211	Belongs to the bacterial ribosomal protein bL27 family
IM698_RS00255	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IM698_RS00260	COG2966	Psort location CytoplasmicMembrane, score
IM698_RS00265	COG3610	response to peptide
IM698_RS00280	COG2967	ApaG domain
IM698_RS00285	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
IM698_RS00290	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
IM698_RS00295	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IM698_RS00300	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
IM698_RS00305	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
IM698_RS00320	COG0066	3-isopropylmalate dehydratase activity
IM698_RS00330	COG0473	3-isopropylmalate dehydrogenase activity
IM698_RS00335	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IM698_RS00370	COG1022	Amp-dependent synthetase and ligase
IM698_RS00375	COG0028	Belongs to the TPP enzyme family
IM698_RS00385	COG3706	GGDEF domain
IM698_RS00395	COG0469	pyruvate kinase activity
IM698_RS00400	COG1349	DNA-binding transcription factor activity
IM698_RS00405	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IM698_RS00410	COG2873	o-acetylhomoserine
IM698_RS00415	COG0582	viral genome integration into host DNA
IM698_RS00475	COG1610	YqeY-like protein
IM698_RS00480	COG0828	Belongs to the bacterial ribosomal protein bS21 family
IM698_RS00485	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IM698_RS00490	COG0596	Alpha beta hydrolase
IM698_RS00495	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
IM698_RS00500	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IM698_RS00505	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IM698_RS00510	COG1968	undecaprenyl-diphosphatase activity
IM698_RS00515	COG0617	tRNA 3'-terminal CCA addition
IM698_RS00520	COG3267	Type II secretory pathway component ExeA
IM698_RS00520	COG3409	Peptidoglycan-binding domain 1 protein
IM698_RS00530	COG4991	sh3 domain protein
IM698_RS00535	COG0306	phosphate transporter
IM698_RS00540	COG1392	Phosphate transport regulator
IM698_RS00545	COG3025	triphosphatase activity
IM698_RS00550	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IM698_RS00560	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
IM698_RS00565	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
IM698_RS00565	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
IM698_RS00570	COG1538	Outer membrane efflux protein
IM698_RS00575	COG0494	nUDIX hydrolase
IM698_RS00580	COG3151	Protein conserved in bacteria
IM698_RS00590	COG3150	esterase
IM698_RS00605	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IM698_RS00610	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IM698_RS00615	COG3105	Protein conserved in bacteria
IM698_RS00620	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
IM698_RS00625	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IM698_RS00630	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
IM698_RS00635	COG0723	plastoquinol--plastocyanin reductase activity
IM698_RS00640	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
IM698_RS00645	COG2857	Cytochrome c1
IM698_RS00650	COG0625	glutathione transferase activity
IM698_RS00655	COG2969	positive regulation of protein catabolic process
IM698_RS00660	COG2823	Periplasmic or secreted lipoprotein
IM698_RS00665	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
IM698_RS00680	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IM698_RS00690	COG0275	rRNA processing
IM698_RS00695	COG3116	cell division
IM698_RS00700	COG0768	penicillin binding
IM698_RS00705	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IM698_RS00710	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IM698_RS00715	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IM698_RS00720	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IM698_RS00725	COG0772	Belongs to the SEDS family
IM698_RS00730	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IM698_RS00735	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IM698_RS00740	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
IM698_RS00745	COG0849	cell division
IM698_RS00750	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IM698_RS00755	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
IM698_RS00760	COG0653	protein targeting
IM698_RS00765	COG0494	nUDIX hydrolase
IM698_RS00770	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
IM698_RS00775	COG0505	Belongs to the CarA family
IM698_RS00780	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
IM698_RS00785	COG0730	response to heat
IM698_RS00790	COG0583	DNA-binding transcription factor activity
IM698_RS00795	COG2860	membrane
IM698_RS00810	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IM698_RS00820	COG0493	'glutamate synthase
IM698_RS00825	COG0069	glutamate synthase activity
IM698_RS00825	COG0070	glutamate synthase
IM698_RS00825	COG0067	glutamate synthase
IM698_RS00835	COG0067	glutamate synthase
IM698_RS00835	COG0069	glutamate synthase activity
IM698_RS00835	COG0070	glutamate synthase
IM698_RS00840	COG1242	4 iron, 4 sulfur cluster binding
IM698_RS00845	COG2203	Gaf domain
IM698_RS00845	COG3706	GGDEF domain
IM698_RS00845	COG4251	negative regulation of phosphorylation
IM698_RS00845	COG5001	Diguanylate cyclase
IM698_RS00850	COG2198	Histidine kinase
IM698_RS00850	COG5002	protein histidine kinase activity
IM698_RS00850	COG0784	Response regulator, receiver
IM698_RS00860	COG0745	RESPONSE REGULATOR receiver
IM698_RS00870	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IM698_RS00885	COG0083	homoserine kinase activity
IM698_RS00890	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IM698_RS00895	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
IM698_RS00900	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
IM698_RS00905	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IM698_RS00920	COG1115	amino acid carrier protein
IM698_RS00925	COG3022	response to hydroperoxide
IM698_RS00930	COG0513	Belongs to the DEAD box helicase family
IM698_RS00935	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
IM698_RS00945	COG0716	FMN binding
IM698_RS00950	COG4974	Belongs to the 'phage' integrase family
IM698_RS00955	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IM698_RS00960	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
IM698_RS00975	COG2204	response regulator
IM698_RS00995	COG0494	nUDIX hydrolase
IM698_RS01005	COG0730	response to heat
IM698_RS01010	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IM698_RS01015	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IM698_RS01020	COG1283	sodium-dependent phosphate transmembrane transporter activity
IM698_RS01025	COG0583	DNA-binding transcription factor activity
IM698_RS01030	COG0640	Transcriptional regulator
IM698_RS01035	COG0268	Binds directly to 16S ribosomal RNA
IM698_RS01040	COG0728	peptidoglycan biosynthetic process
IM698_RS01045	COG0196	riboflavin kinase activity
IM698_RS01050	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IM698_RS01060	COG1047	Peptidyl-prolyl cis-trans
IM698_RS01065	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
IM698_RS01070	COG3279	Response regulator of the LytR AlgR family
IM698_RS01075	COG3275	phosphorelay sensor kinase activity
IM698_RS01080	COG3385	transposase activity
IM698_RS01085	COG1966	Carbon starvation protein
IM698_RS01095	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
IM698_RS01100	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
IM698_RS01105	COG2971	BadF BadG BcrA BcrD
IM698_RS01125	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IM698_RS01130	COG0287	Prephenate dehydrogenase
IM698_RS01130	COG1605	Chorismate mutase
IM698_RS01135	COG0739	heme binding
IM698_RS01145	COG0488	(ABC) transporter
IM698_RS01155	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
IM698_RS01160	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
IM698_RS01165	COG5001	Diguanylate cyclase
IM698_RS01170	COG0077	Prephenate dehydratase
IM698_RS01170	COG1605	Chorismate mutase
IM698_RS01175	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IM698_RS01180	COG0741	lytic transglycosylase activity
IM698_RS01185	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IM698_RS01190	COG0564	pseudouridine synthase activity
IM698_RS01235	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
IM698_RS01245	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IM698_RS01250	COG0826	peptidase U32
IM698_RS01255	COG2974	May be involved in recombination
IM698_RS01260	COG0745	RESPONSE REGULATOR receiver
IM698_RS01265	COG5002	protein histidine kinase activity
IM698_RS01275	COG0248	Ppx GppA phosphatase
IM698_RS01280	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
IM698_RS01290	COG0581	inorganic phosphate transmembrane transporter activity
IM698_RS01295	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IM698_RS01300	COG0704	Plays a role in the regulation of phosphate uptake
IM698_RS01315	COG3142	Participates in the control of copper homeostasis
IM698_RS01320	COG0450	alkyl hydroperoxide reductase
IM698_RS01325	COG0583	DNA-binding transcription factor activity
IM698_RS01330	COG0517	IMP dehydrogenase activity
IM698_RS01335	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
IM698_RS01340	COG0343	queuine tRNA-ribosyltransferase activity
IM698_RS01345	COG1862	Preprotein translocase
IM698_RS01350	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IM698_RS01355	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IM698_RS01360	COG0483	inositol monophosphate 1-phosphatase activity
IM698_RS01365	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
IM698_RS01370	COG1959	2 iron, 2 sulfur cluster binding
IM698_RS01375	COG1104	cysteine desulfurase activity
IM698_RS01380	COG0822	iron-sulfur transferase activity
IM698_RS01390	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
IM698_RS01395	COG0443	Heat shock 70 kDa protein
IM698_RS01405	COG2975	iron-sulfur cluster assembly
IM698_RS01410	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IM698_RS01415	COG0105	UTP biosynthetic process
IM698_RS01420	COG0820	rRNA (adenine-C2-)-methyltransferase activity
IM698_RS01430	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
IM698_RS01435	COG0124	histidyl-tRNA synthetase
IM698_RS01440	COG2976	Protein conserved in bacteria
IM698_RS01445	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IM698_RS01450	COG1160	GTP binding
IM698_RS01460	COG3706	GGDEF domain
IM698_RS01500	COG0831	urea catabolic process
IM698_RS01505	COG0832	Belongs to the urease beta subunit family
IM698_RS01510	COG0804	urea catabolic process
IM698_RS01515	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
IM698_RS01530	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
IM698_RS01535	COG1570	exodeoxyribonuclease VII activity
IM698_RS01540	COG0516	GMP reductase activity
IM698_RS01540	COG0517	IMP dehydrogenase activity
IM698_RS01545	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IM698_RS01545	COG0519	Catalyzes the synthesis of GMP from XMP
IM698_RS01555	COG1757	Na H antiporter
IM698_RS01560	COG1584	GPR1 FUN34 yaaH family protein
IM698_RS01565	COG1115	amino acid carrier protein
IM698_RS01570	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
IM698_RS01575	COG0204	Acyl-transferase
IM698_RS01600	COG0189	ligase activity
IM698_RS01600	COG4067	protein conserved in archaea
IM698_RS01615	COG2867	negative regulation of translational initiation
IM698_RS01620	COG2914	Belongs to the UPF0125 (RnfH) family
IM698_RS01625	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IM698_RS01630	COG0497	DNA recombination
IM698_RS01635	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IM698_RS01640	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IM698_RS01655	COG0443	Heat shock 70 kDa protein
IM698_RS01660	COG0484	heat shock protein binding
IM698_RS01690	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
IM698_RS01695	COG1253	flavin adenine dinucleotide binding
IM698_RS01715	COG0047	phosphoribosylformylglycinamidine synthase activity
IM698_RS01715	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IM698_RS01725	COG2171	N-acyltransferase activity
IM698_RS01730	COG2095	MarC family integral membrane protein
IM698_RS01745	COG3141	response to X-ray
IM698_RS01760	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
IM698_RS01770	COG1074	ATP-dependent DNA helicase activity
IM698_RS01775	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IM698_RS01785	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
IM698_RS01785	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
IM698_RS01795	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
IM698_RS01800	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
IM698_RS01805	COG2166	iron-sulfur cluster assembly
IM698_RS01810	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IM698_RS01815	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IM698_RS01820	COG3248	Nucleoside-binding outer membrane protein
IM698_RS01835	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IM698_RS01845	COG2813	Specifically methylates the guanine in position
IM698_RS01850	COG0271	Belongs to the BolA IbaG family
IM698_RS01855	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
IM698_RS01860	COG1805	sodium ion transport
IM698_RS01870	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
IM698_RS01875	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
IM698_RS01880	COG2871	sodium ion transport
IM698_RS01885	COG1477	protein flavinylation
IM698_RS01890	COG2991	Protein conserved in bacteria
IM698_RS01900	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IM698_RS01920	COG0733	neurotransmitter:sodium symporter activity
IM698_RS01925	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IM698_RS01930	COG0321	lipoyl(octanoyl) transferase activity
IM698_RS01940	COG1686	Belongs to the peptidase S11 family
IM698_RS01945	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
IM698_RS01950	COG0772	Belongs to the SEDS family
IM698_RS01955	COG0768	penicillin binding
IM698_RS01960	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IM698_RS01965	COG0799	negative regulation of ribosome biogenesis
IM698_RS01970	COG1466	dna polymerase III delta subunit
IM698_RS01975	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
IM698_RS01980	COG0495	leucyl-tRNA aminoacylation
IM698_RS01985	COG2888	peptidyl-tyrosine sulfation
IM698_RS01990	COG0815	Transfers the fatty acyl group on membrane lipoproteins
IM698_RS01995	COG4535	Mg2 and Co2 transporter CorC
IM698_RS02000	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IM698_RS02005	COG1702	phosphate starvation-inducible protein PhoH
IM698_RS02015	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IM698_RS02020	COG2706	6-phosphogluconolactonase activity
IM698_RS02125	COG0193	aminoacyl-tRNA hydrolase activity
IM698_RS02130	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IM698_RS02135	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
IM698_RS02140	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
IM698_RS02145	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
IM698_RS02150	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IM698_RS02155	COG2890	protein-(glutamine-N5) methyltransferase activity
IM698_RS02160	COG3094	Invasion gene expression up-regulator, SirB
IM698_RS02165	COG2912	Transglutaminase-like superfamily
IM698_RS02170	COG2877	3-deoxy-8-phosphooctulonate synthase activity
IM698_RS02180	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IM698_RS02185	COG1187	pseudouridine synthase activity
IM698_RS02190	COG2840	Smr protein MutS2
IM698_RS02230	COG2217	Heavy metal translocating P-type atpase
IM698_RS02230	COG2608	mercury ion transmembrane transporter activity
IM698_RS02250	COG1028	Short-chain dehydrogenase reductase Sdr
IM698_RS02290	COG1216	Glycosyl transferase, family 2
IM698_RS02310	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IM698_RS02315	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IM698_RS02375	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
IM698_RS02380	COG0784	Response regulator, receiver
IM698_RS02380	COG0835	chemotaxis
IM698_RS02385	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
IM698_RS02390	COG1815	bacterial-type flagellum-dependent cell motility
IM698_RS02395	COG1558	bacterial-type flagellum-dependent cell motility
IM698_RS02405	COG1749	Flagellar hook protein flgE
IM698_RS02410	COG4787	bacterial-type flagellum-dependent cell motility
IM698_RS02420	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
IM698_RS02425	COG1706	bacterial-type flagellum-dependent cell motility
IM698_RS02430	COG1705	Flagellar rod assembly protein muramidase FlgJ
IM698_RS02430	COG3951	Flagellar rod assembly protein muramidase FlgJ
IM698_RS02450	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IM698_RS02455	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IM698_RS02460	COG1334	flagellar protein FlaG
IM698_RS02465	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
IM698_RS02475	COG1516	flagellar protein fliS
IM698_RS02495	COG1677	Flagellar hook-basal body complex protein FliE
IM698_RS02505	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IM698_RS02555	COG1987	bacterial-type flagellum assembly
IM698_RS02560	COG1684	flagellar biosynthetic protein fliR
IM698_RS02595	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
IM698_RS02600	COG0643	Histidine kinase
IM698_RS02600	COG0784	Response regulator, receiver
IM698_RS02600	COG2198	Histidine kinase
IM698_RS02605	COG2201	protein-glutamate methylesterase activity
IM698_RS02610	COG1192	Involved in chromosome partitioning
IM698_RS02620	COG0835	chemotaxis
IM698_RS02630	COG4133	protoheme IX ABC transporter activity
IM698_RS02635	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IM698_RS02640	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IM698_RS02645	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IM698_RS02650	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
IM698_RS02655	COG1138	Cytochrome C-type biogenesis protein
IM698_RS02660	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IM698_RS02665	COG4235	cytochrome complex assembly
IM698_RS02665	COG3088	subunit of a heme lyase
IM698_RS02670	COG3088	subunit of a heme lyase
IM698_RS02670	COG4235	cytochrome complex assembly
IM698_RS02675	COG2853	Lipoprotein
IM698_RS02705	COG0183	Belongs to the thiolase family
IM698_RS02710	COG1024	Enoyl-CoA hydratase
IM698_RS02710	COG1250	3-hydroxyacyl-CoA dehydrogenase
IM698_RS02720	COG2062	phosphohistidine phosphatase, SixA
IM698_RS02725	COG2840	Smr protein MutS2
IM698_RS02730	COG2890	protein-(glutamine-N5) methyltransferase activity
IM698_RS02735	COG1280	lysine exporter protein (LysE YggA)
IM698_RS02740	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
IM698_RS02760	COG1175	transmembrane transport
IM698_RS02770	COG3842	ATPase activity
IM698_RS02775	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IM698_RS02780	COG2070	2-Nitropropane dioxygenase
IM698_RS02780	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
IM698_RS02810	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IM698_RS02815	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
IM698_RS02820	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
IM698_RS02830	COG2204	response regulator
IM698_RS02840	COG0544	peptidyl-prolyl cis-trans isomerase activity
IM698_RS02845	COG0740	serine-type endopeptidase activity
IM698_RS02850	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IM698_RS02855	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
IM698_RS02860	COG0776	regulation of translation
IM698_RS02865	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IM698_RS02870	COG2183	response to ionizing radiation
IM698_RS02885	COG0232	Belongs to the dGTPase family. Type 2 subfamily
IM698_RS02890	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
IM698_RS02895	COG0436	Aminotransferase
IM698_RS02900	COG1169	isochorismate synthase
IM698_RS02905	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
IM698_RS02910	COG2267	carboxylic ester hydrolase activity
IM698_RS02915	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
IM698_RS02935	COG2855	membrane
IM698_RS02990	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IM698_RS03000	COG1454	alcohol dehydrogenase
IM698_RS03030	COG0641	radical SAM
IM698_RS03040	COG1309	transcriptional regulator
IM698_RS03080	COG1902	pentaerythritol trinitrate reductase activity
IM698_RS03085	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IM698_RS03090	COG1522	sequence-specific DNA binding
IM698_RS03100	COG1946	Acyl-CoA thioesterase
IM698_RS03105	COG3126	Type III secretion system lipoprotein chaperone (YscW)
IM698_RS03145	COG0840	transmembrane signaling receptor activity
IM698_RS03150	COG3655	Transcriptional regulator
IM698_RS03165	COG3385	transposase activity
IM698_RS03170	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
IM698_RS03170	COG4124	Belongs to the glycosyl hydrolase 26 family
IM698_RS03220	COG0328	RNA-DNA hybrid ribonuclease activity
IM698_RS03220	COG3341	Caulimovirus viroplasmin
IM698_RS03225	COG0438	transferase activity, transferring glycosyl groups
IM698_RS03230	COG0463	Glycosyl transferase, family 2
IM698_RS03230	COG1216	Glycosyl transferase, family 2
IM698_RS03265	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
IM698_RS03280	COG0789	Transcriptional regulator
IM698_RS03285	COG3394	polysaccharide catabolic process
IM698_RS03295	COG0583	DNA-binding transcription factor activity
IM698_RS03320	COG3119	arylsulfatase activity
IM698_RS03325	COG1609	Transcriptional regulator
IM698_RS03350	COG1760	l-serine dehydratase
IM698_RS03355	COG1522	sequence-specific DNA binding
IM698_RS03360	COG1280	lysine exporter protein (LysE YggA)
IM698_RS03385	COG2207	Transcriptional regulator
IM698_RS03385	COG3708	Transcriptional regulator
IM698_RS03395	COG2233	PERMEase
IM698_RS03400	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
IM698_RS03405	COG1227	inorganic diphosphatase activity
IM698_RS03410	COG0494	nUDIX hydrolase
IM698_RS03415	COG3153	acetyltransferase
IM698_RS03460	COG0446	pyridine nucleotide-disulphide oxidoreductase
IM698_RS03470	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
IM698_RS03485	COG1228	amidohydrolase
IM698_RS03500	COG3040	lipid binding
IM698_RS03505	COG1309	transcriptional regulator
IM698_RS03520	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
IM698_RS03525	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IM698_RS03530	COG1845	cytochrome c oxidase, subunit III
IM698_RS03535	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
IM698_RS03550	COG2015	COG2015, Alkyl sulfatase and related hydrolases
IM698_RS03575	COG0583	DNA-binding transcription factor activity
IM698_RS03580	COG0346	lactoylglutathione lyase activity
IM698_RS03585	COG1902	pentaerythritol trinitrate reductase activity
IM698_RS03615	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IM698_RS03640	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
IM698_RS03640	COG0617	tRNA 3'-terminal CCA addition
IM698_RS03640	COG0517	IMP dehydrogenase activity
IM698_RS03670	COG0537	adenosine 5'-monophosphoramidase activity
IM698_RS03695	COG3150	esterase
IM698_RS03700	COG1252	NADH dehydrogenase
IM698_RS03715	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IM698_RS03725	COG4591	ABC-type transport system involved in lipoprotein release permease component
IM698_RS03730	COG1136	(ABC) transporter
IM698_RS03735	COG4591	ABC-type transport system involved in lipoprotein release permease component
IM698_RS03745	COG0658	competence protein
IM698_RS03745	COG2333	competence protein COMEC
IM698_RS03750	COG1132	(ABC) transporter
IM698_RS03755	COG1663	tetraacyldisaccharide 4'-kinase activity
IM698_RS03760	COG2835	tetraacyldisaccharide 4'-kinase activity
IM698_RS03765	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
IM698_RS03770	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
IM698_RS03775	COG0539	negative regulation of cytoplasmic translation
IM698_RS03780	COG0776	regulation of translation
IM698_RS03785	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
IM698_RS03790	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
IM698_RS03795	COG0284	orotidine-5'-phosphate decarboxylase activity
IM698_RS03810	COG0583	DNA-binding transcription factor activity
IM698_RS03820	COG0686	Belongs to the AlaDH PNT family
IM698_RS03825	COG1522	sequence-specific DNA binding
IM698_RS03830	COG1674	ftsk spoiiie
IM698_RS03835	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
IM698_RS03840	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
IM698_RS03845	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IM698_RS03850	COG0745	RESPONSE REGULATOR receiver
IM698_RS03860	COG2205	protein histidine kinase activity
IM698_RS03860	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IM698_RS03865	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IM698_RS03870	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
IM698_RS03875	COG0156	8-amino-7-oxononanoate synthase activity
IM698_RS03880	COG2226	methyltransferase
IM698_RS03885	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
IM698_RS03895	COG0501	Belongs to the peptidase M48B family
IM698_RS03900	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IM698_RS03905	COG2915	High frequency lysogenization protein hflD homolog
IM698_RS03920	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IM698_RS03925	COG2916	Histone family protein nucleoid-structuring protein H-NS
IM698_RS03930	COG1757	Na H antiporter
IM698_RS03945	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IM698_RS03950	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
IM698_RS03950	COG0131	Imidazoleglycerol-phosphate dehydratase
IM698_RS03955	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IM698_RS03960	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
IM698_RS03965	COG0107	imidazoleglycerol-phosphate synthase activity
IM698_RS03970	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IM698_RS03970	COG0140	phosphoribosyl-ATP diphosphatase activity
IM698_RS03975	COG3012	SEC-C Motif Domain Protein
IM698_RS03980	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
IM698_RS03985	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IM698_RS03990	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IM698_RS03995	COG0215	cysteine-tRNA ligase activity
IM698_RS04025	COG2116	formate transmembrane transporter activity
IM698_RS04030	COG0390	transport system, permease component
IM698_RS04035	COG4459	periplasmic nitrate reductase
IM698_RS04040	COG3005	denitrification pathway
IM698_RS04045	COG0243	molybdopterin cofactor binding
IM698_RS04055	COG1227	inorganic diphosphatase activity
IM698_RS04070	COG4172	Belongs to the ABC transporter superfamily
IM698_RS04085	COG4168	peptide transport system, permease
IM698_RS04090	COG4166	transmembrane transport
IM698_RS04095	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
IM698_RS04100	COG1842	Phage shock protein A
IM698_RS04110	COG1983	PspC domain protein
IM698_RS04115	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IM698_RS04130	COG2818	Glycosylase
IM698_RS04145	COG0626	cystathionine gamma-synthase activity
IM698_RS04155	COG0733	neurotransmitter:sodium symporter activity
IM698_RS04165	COG0564	pseudouridine synthase activity
IM698_RS04170	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
IM698_RS04170	COG0116	Belongs to the methyltransferase superfamily
IM698_RS04175	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IM698_RS04180	COG4136	ATPase activity
IM698_RS04185	COG4135	transport system, permease component
IM698_RS04190	COG4134	Bacterial extracellular solute-binding protein
IM698_RS04200	COG3313	Fe-S protein
IM698_RS04220	COG0513	Belongs to the DEAD box helicase family
IM698_RS04225	COG1280	lysine exporter protein (LysE YggA)
IM698_RS04235	COG2866	Carboxypeptidase
IM698_RS04245	COG3005	denitrification pathway
IM698_RS04250	COG0243	molybdopterin cofactor binding
IM698_RS04270	COG4176	ABC-type proline glycine betaine transport system permease component
IM698_RS04275	COG2113	Glycine betaine
IM698_RS04285	COG0583	DNA-binding transcription factor activity
IM698_RS04290	COG2995	paraquat-inducible protein a
IM698_RS04295	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IM698_RS04295	COG3008	intermembrane lipid transfer
IM698_RS04330	COG2165	general secretion pathway protein
IM698_RS04345	COG4796	Type ii and iii secretion system protein
IM698_RS04365	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IM698_RS04370	COG1459	type II secretion system
IM698_RS04425	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
IM698_RS04435	COG0586	Pfam SNARE associated Golgi protein
IM698_RS04445	COG0642	Histidine kinase
IM698_RS04460	COG1061	Type III restriction enzyme res subunit
IM698_RS04470	COG2814	Major facilitator Superfamily
IM698_RS04480	COG0702	epimerase
IM698_RS04485	COG0534	Mate efflux family protein
IM698_RS04505	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
IM698_RS04510	COG2885	chlorophyll binding
IM698_RS04510	COG3047	cAMP biosynthetic process
IM698_RS04535	COG3385	transposase activity
IM698_RS04540	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
IM698_RS04545	COG3273	potassium ion transport
IM698_RS04545	COG2985	domain, Protein
IM698_RS04550	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IM698_RS04560	COG1737	Transcriptional regulator
IM698_RS04565	COG0076	glutamate decarboxylase activity
IM698_RS04575	COG2431	L-lysine efflux transmembrane transporter activity
IM698_RS04585	COG3070	regulator of competence-specific genes
IM698_RS04595	COG2204	response regulator
IM698_RS04600	COG3852	Histidine kinase
IM698_RS04610	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IM698_RS04625	COG2258	MOSC domain
IM698_RS04630	COG2176	DNA-directed DNA polymerase activity
IM698_RS04645	COG1448	Aminotransferase
IM698_RS04650	COG2770	Histidine kinase
IM698_RS04650	COG3437	response regulator, receiver
IM698_RS04660	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IM698_RS04670	COG0017	Asparaginyl-tRNA synthetase
IM698_RS04675	COG0659	secondary active sulfate transmembrane transporter activity
IM698_RS04680	COG0840	transmembrane signaling receptor activity
IM698_RS04690	COG0814	amino acid
IM698_RS04695	COG1760	l-serine dehydratase
IM698_RS04700	COG0814	amino acid
IM698_RS04705	COG0494	nUDIX hydrolase
IM698_RS04715	COG5002	protein histidine kinase activity
IM698_RS04715	COG0784	Response regulator, receiver
IM698_RS04720	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IM698_RS04735	COG3106	COG3106 Predicted ATPase
IM698_RS04750	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IM698_RS04765	COG0443	Heat shock 70 kDa protein
IM698_RS04780	COG3706	GGDEF domain
IM698_RS04800	COG3710	Transcriptional regulator
IM698_RS04830	COG1643	Atp-dependent helicase
IM698_RS04870	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IM698_RS04875	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IM698_RS04875	COG0072	phenylalanine-tRNA ligase activity
IM698_RS04880	COG1196	nuclear chromosome segregation
IM698_RS04935	COG0302	gtp cyclohydrolase
IM698_RS04940	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IM698_RS04945	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IM698_RS04960	COG1464	Belongs to the NlpA lipoprotein family
IM698_RS04970	COG1522	sequence-specific DNA binding
IM698_RS05025	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
IM698_RS05050	COG0776	regulation of translation
IM698_RS05070	COG0840	transmembrane signaling receptor activity
IM698_RS05080	COG0583	DNA-binding transcription factor activity
IM698_RS05090	COG2175	clavaminate synthase activity
IM698_RS05105	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IM698_RS05115	COG2988	succinylglutamate desuccinylase activity
IM698_RS05120	COG0523	cobalamin synthesis protein
IM698_RS05130	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
IM698_RS05140	COG0776	regulation of translation
IM698_RS05150	COG0500	methyltransferase
IM698_RS05160	COG0295	cytidine deaminase activity
IM698_RS05165	COG1346	cytolysis
IM698_RS05175	COG2925	Exonuclease
IM698_RS05220	COG3568	Endonuclease Exonuclease Phosphatase
IM698_RS05225	COG3122	Protein conserved in bacteria
IM698_RS05240	COG4989	oxidoreductase activity
IM698_RS05250	COG1823	symporter activity
IM698_RS05255	COG0702	epimerase
IM698_RS05260	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IM698_RS05265	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
IM698_RS05270	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
IM698_RS05290	COG2988	succinylglutamate desuccinylase activity
IM698_RS05295	COG4139	cobalamin transport
IM698_RS05300	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
IM698_RS05305	COG0747	negative chemotaxis
IM698_RS05310	COG0601	transmembrane transport
IM698_RS05315	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IM698_RS05335	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IM698_RS05340	COG1271	oxidase subunit
IM698_RS05345	COG1294	oxidase, subunit
IM698_RS05355	COG1247	-acetyltransferase
IM698_RS05375	COG2814	Major facilitator Superfamily
IM698_RS05380	COG0583	DNA-binding transcription factor activity
IM698_RS05390	COG1451	nucleotide metabolic process
IM698_RS05400	COG3063	Type IV pilus biogenesis stability protein PilW
IM698_RS05405	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
IM698_RS05420	COG2195	Cleaves the N-terminal amino acid of tripeptides
IM698_RS05425	COG3706	GGDEF domain
IM698_RS05490	COG1401	restriction endodeoxyribonuclease activity
IM698_RS05500	COG1196	nuclear chromosome segregation
IM698_RS05515	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
IM698_RS05530	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IM698_RS05635	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IM698_RS05650	COG0840	transmembrane signaling receptor activity
IM698_RS05665	COG3469	chitinase activity
IM698_RS05675	COG4771	TonB-dependent receptor
IM698_RS05685	COG2199	diguanylate cyclase activity
IM698_RS05690	COG0454	-acetyltransferase
IM698_RS05710	COG0420	3'-5' exonuclease activity
IM698_RS05715	COG0419	ATPase involved in DNA repair
IM698_RS05735	COG3046	protein related to deoxyribodipyrimidine photolyase
IM698_RS05740	COG0415	Belongs to the DNA photolyase family
IM698_RS05745	COG0589	response to stress
IM698_RS05770	COG1120	ATPase activity
IM698_RS05775	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IM698_RS05780	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IM698_RS05785	COG4615	Cyclic peptide transporter
IM698_RS05805	COG4774	siderophore transport
IM698_RS05825	COG2271	Major facilitator Superfamily
IM698_RS05835	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IM698_RS05855	COG0494	nUDIX hydrolase
IM698_RS05870	COG1187	pseudouridine synthase activity
IM698_RS05880	COG0110	maltose O-acetyltransferase activity
IM698_RS05890	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IM698_RS05905	COG0494	nUDIX hydrolase
IM698_RS05935	COG0346	lactoylglutathione lyase activity
IM698_RS05955	COG1619	proteins homologs of microcin C7 resistance protein MccF
IM698_RS05975	COG0653	protein targeting
IM698_RS05985	COG1028	Short-chain dehydrogenase reductase Sdr
IM698_RS06020	COG0786	glutamate:sodium symporter activity
IM698_RS06035	COG0826	peptidase U32
IM698_RS06040	COG3385	transposase activity
IM698_RS06055	COG1126	abc transporter atp-binding protein
IM698_RS06060	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IM698_RS06065	COG4215	(ABC) transporter
IM698_RS06070	COG4160	amino acid transport
IM698_RS06100	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IM698_RS06130	COG1742	UPF0060 membrane protein
IM698_RS06155	COG0583	DNA-binding transcription factor activity
IM698_RS06190	COG0741	lytic transglycosylase activity
IM698_RS06195	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
IM698_RS06210	COG2066	Belongs to the glutaminase family
IM698_RS06220	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IM698_RS06225	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IM698_RS06240	COG0762	integral membrane protein
IM698_RS06245	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IM698_RS06250	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IM698_RS06265	COG3385	transposase activity
IM698_RS06275	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IM698_RS06280	COG1678	Uncharacterized ACR, COG1678
IM698_RS06285	COG0189	ligase activity
IM698_RS06290	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IM698_RS06295	COG2356	endonuclease I
IM698_RS06300	COG3091	SprT-like family
IM698_RS06310	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IM698_RS06315	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IM698_RS06330	COG0191	fructose-bisphosphate aldolase activity
IM698_RS06335	COG0668	transmembrane transport
IM698_RS06340	COG1279	arginine transmembrane transporter activity
IM698_RS06355	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IM698_RS06360	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
IM698_RS06365	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IM698_RS06375	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
IM698_RS06380	COG3079	Belongs to the UPF0149 family
IM698_RS06385	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IM698_RS06390	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IM698_RS06405	COG0354	folic acid binding
IM698_RS06410	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
IM698_RS06420	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
IM698_RS06425	COG1595	DNA-templated transcription, initiation
IM698_RS06445	COG0481	GTPase activity
IM698_RS06455	COG0571	ribonuclease III activity
IM698_RS06460	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IM698_RS06465	COG1381	Involved in DNA repair and RecF pathway recombination
IM698_RS06470	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
IM698_RS06475	COG0736	holo-[acyl-carrier-protein] synthase activity
IM698_RS06480	COG3850	Histidine kinase
IM698_RS06480	COG3437	response regulator, receiver
IM698_RS06480	COG2205	protein histidine kinase activity
IM698_RS06480	COG4999	Histidine kinase
IM698_RS06485	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IM698_RS06490	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IM698_RS06495	COG3956	TIGRFAM MazG family protein
IM698_RS06500	COG0504	CTP synthase activity
IM698_RS06505	COG0148	phosphopyruvate hydratase activity
IM698_RS06510	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
IM698_RS06515	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
IM698_RS06525	COG0585	pseudouridine synthase activity
IM698_RS06530	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
IM698_RS06535	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
IM698_RS06545	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IM698_RS06550	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IM698_RS06555	COG1546	Belongs to the CinA family
IM698_RS06560	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IM698_RS06570	COG0527	aspartate kinase activity
IM698_RS06630	COG3630	sodium ion export across plasma membrane
IM698_RS06635	COG5016	pyruvate
IM698_RS06635	COG0511	ligase activity, forming carbon-carbon bonds
IM698_RS06640	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
IM698_RS06650	COG1238	metal cluster binding
IM698_RS06655	COG0612	Peptidase, M16
IM698_RS06660	COG2918	glutathione biosynthetic process
IM698_RS06670	COG1854	S-ribosylhomocysteine lyase activity
IM698_RS06675	COG4536	flavin adenine dinucleotide binding
IM698_RS06680	COG4137	Cytochrome C assembly protein
IM698_RS06685	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IM698_RS06690	COG0228	four-way junction DNA binding
IM698_RS06695	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IM698_RS06700	COG0336	Belongs to the RNA methyltransferase TrmD family
IM698_RS06705	COG0335	large ribosomal subunit rRNA binding
IM698_RS06715	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
IM698_RS06720	COG0237	dephospho-CoA kinase activity
IM698_RS06730	COG1459	type II secretion system
IM698_RS06735	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IM698_RS06745	COG0157	Belongs to the NadC ModD family
IM698_RS06755	COG2186	Transcriptional regulator
IM698_RS06760	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
IM698_RS06765	COG0508	dehydrogenase complex catalyzes the overall conversion of
IM698_RS06770	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IM698_RS06790	COG0288	reversible hydration of carbon dioxide
IM698_RS06795	COG0659	secondary active sulfate transmembrane transporter activity
IM698_RS06800	COG1131	(ABC) transporter
IM698_RS06805	COG0842	Transport permease protein
IM698_RS06810	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
IM698_RS06815	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
IM698_RS06820	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IM698_RS06840	COG1489	DNA binding
IM698_RS06845	COG1643	Atp-dependent helicase
IM698_RS06850	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IM698_RS06855	COG1752	Esterase of the alpha-beta hydrolase superfamily
IM698_RS06860	COG1049	propionate catabolic process, 2-methylcitrate cycle
IM698_RS06875	COG0004	ammonium transporteR
IM698_RS06880	COG1840	ABC-type Fe3 transport system, periplasmic component
IM698_RS06890	COG3842	ATPase activity
IM698_RS06895	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IM698_RS06910	COG2971	BadF BadG BcrA BcrD
IM698_RS06920	COG4608	Belongs to the ABC transporter superfamily
IM698_RS06925	COG0444	Belongs to the ABC transporter superfamily
IM698_RS06930	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IM698_RS06940	COG0747	negative chemotaxis
IM698_RS06950	COG2813	Specifically methylates the guanine in position
IM698_RS06955	COG0628	permease
IM698_RS06965	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
IM698_RS06970	COG0316	Belongs to the HesB IscA family
IM698_RS06985	COG0739	heme binding
IM698_RS06990	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IM698_RS06995	COG2239	Acts as a magnesium transporter
IM698_RS07000	COG2027	D-alanyl-D-alanine carboxypeptidase
IM698_RS07005	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
IM698_RS07010	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IM698_RS07015	COG1534	Rna-binding protein
IM698_RS07020	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
IM698_RS07025	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IM698_RS07030	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IM698_RS07035	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IM698_RS07040	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
IM698_RS07055	COG0779	Required for maturation of 30S ribosomal subunits
IM698_RS07060	COG0195	Participates in both transcription termination and antitermination
IM698_RS07065	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IM698_RS07070	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IM698_RS07075	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IM698_RS07080	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IM698_RS07085	COG1185	polyribonucleotide nucleotidyltransferase activity
IM698_RS07100	COG0534	Mate efflux family protein
IM698_RS07105	COG0826	peptidase U32
IM698_RS07110	COG0826	peptidase U32
IM698_RS07120	COG3154	lipid carrier protein
IM698_RS07125	COG3153	acetyltransferase
IM698_RS07140	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
IM698_RS07165	COG0084	hydrolase, TatD family'
IM698_RS07170	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IM698_RS07175	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
IM698_RS07180	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
IM698_RS07190	COG0813	purine-nucleoside phosphorylase activity
IM698_RS07200	COG0560	Phosphoserine phosphatase
IM698_RS07210	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IM698_RS07215	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IM698_RS07245	COG4628	conserved protein (DUF2132)
IM698_RS07250	COG0583	DNA-binding transcription factor activity
IM698_RS07260	COG1022	Amp-dependent synthetase and ligase
IM698_RS07275	COG0583	DNA-binding transcription factor activity
IM698_RS07290	COG4964	Belongs to the GSP D family
IM698_RS07300	COG0455	bacterial-type flagellum organization
IM698_RS07345	COG2059	Chromate
IM698_RS07350	COG0583	DNA-binding transcription factor activity
IM698_RS07355	COG1609	Transcriptional regulator
IM698_RS07365	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IM698_RS07370	COG0534	Mate efflux family protein
IM698_RS07380	COG1175	transmembrane transport
IM698_RS07385	COG0395	ABC-type sugar transport system, permease component
IM698_RS07395	COG3250	beta-galactosidase activity
IM698_RS07400	COG3408	Glycogen debranching enzyme
IM698_RS07400	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
IM698_RS07410	COG0531	amino acid
IM698_RS07415	COG0531	amino acid
IM698_RS07420	COG2731	YhcH YjgK YiaL family protein
IM698_RS07425	COG3250	beta-galactosidase activity
IM698_RS07430	COG1609	Transcriptional regulator
IM698_RS07435	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IM698_RS07440	COG1085	galactose-1-phosphate uridylyltransferase
IM698_RS07450	COG2017	converts alpha-aldose to the beta-anomer
IM698_RS07455	COG1609	Transcriptional regulator
IM698_RS07460	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IM698_RS07475	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IM698_RS07495	COG2195	Cleaves the N-terminal amino acid of tripeptides
IM698_RS07500	COG2252	PERMEase
IM698_RS07505	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
IM698_RS07510	COG1073	alpha beta
IM698_RS07520	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IM698_RS07525	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IM698_RS07530	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IM698_RS07535	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IM698_RS07535	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IM698_RS07555	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IM698_RS07560	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
IM698_RS07565	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
IM698_RS07570	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IM698_RS07575	COG0142	geranyltranstransferase activity
IM698_RS07580	COG1722	exodeoxyribonuclease VII activity
IM698_RS07585	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
IM698_RS07595	COG0301	tRNA thio-modification
IM698_RS07595	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IM698_RS07600	COG0583	DNA-binding transcription factor activity
IM698_RS07615	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
IM698_RS07620	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IM698_RS07625	COG1611	Belongs to the LOG family
IM698_RS07640	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
IM698_RS07640	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
IM698_RS07650	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
IM698_RS07655	COG4580	involved in the transport of maltose and maltodextrins
IM698_RS07660	COG1464	Belongs to the NlpA lipoprotein family
IM698_RS07665	COG2011	ABC-type metal ion transport system permease component
IM698_RS07670	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IM698_RS07675	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
IM698_RS07685	COG1609	Transcriptional regulator
IM698_RS07690	COG1263	PTS System
IM698_RS07690	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IM698_RS07695	COG0366	Alpha amylase catalytic
IM698_RS07720	COG3385	transposase activity
IM698_RS07740	COG0442	prolyl-tRNA aminoacylation
IM698_RS07745	COG1720	tRNA m6t6A37 methyltransferase activity
IM698_RS07750	COG0254	rRNA binding
IM698_RS07760	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
IM698_RS07770	COG1671	Belongs to the UPF0178 family
IM698_RS07795	COG3098	single-species biofilm formation
IM698_RS07800	COG0564	pseudouridine synthase activity
IM698_RS07810	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
IM698_RS07815	COG0024	Methionine aminopeptidase
IM698_RS07820	COG0052	Belongs to the universal ribosomal protein uS2 family
IM698_RS07825	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IM698_RS07830	COG0528	UMP kinase activity
IM698_RS07835	COG0233	cytoplasmic translational termination
IM698_RS07840	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IM698_RS07845	COG0575	Belongs to the CDS family
IM698_RS07855	COG0750	zinc metalloprotease
IM698_RS07865	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
IM698_RS07870	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IM698_RS07875	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
IM698_RS07880	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IM698_RS07890	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IM698_RS07895	COG0587	DNA-directed DNA polymerase activity
IM698_RS07900	COG0825	malonyl-CoA metabolic process
IM698_RS07905	COG0037	tRNA processing
IM698_RS07915	COG0347	Belongs to the P(II) protein family
IM698_RS07920	COG3021	interspecies interaction between organisms
IM698_RS07930	COG1388	LysM domain
IM698_RS07930	COG0741	lytic transglycosylase activity
IM698_RS07935	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IM698_RS07940	COG2226	methyltransferase
IM698_RS07945	COG0328	RNA-DNA hybrid ribonuclease activity
IM698_RS07950	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IM698_RS07960	COG1960	acyl-CoA dehydrogenase activity
IM698_RS07965	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
IM698_RS07970	COG0121	glutamine amidotransferase
IM698_RS07975	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IM698_RS07980	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
IM698_RS07990	COG2233	PERMEase
IM698_RS08010	COG1393	Belongs to the ArsC family
IM698_RS08015	COG4783	chaperone-mediated protein folding
IM698_RS08030	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IM698_RS08035	COG2716	regulation of RNA biosynthetic process
IM698_RS08040	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IM698_RS08045	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
IM698_RS08060	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IM698_RS08065	COG1393	Belongs to the ArsC family
IM698_RS08090	COG2837	iron assimilation
IM698_RS08095	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IM698_RS08100	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IM698_RS08105	COG2190	(PTS) system
IM698_RS08115	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IM698_RS08125	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
IM698_RS08130	COG3115	cell septum assembly
IM698_RS08135	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IM698_RS08150	COG0789	Transcriptional regulator
IM698_RS08160	COG0330	HflC and HflK could
IM698_RS08165	COG3118	belongs to the thioredoxin family
IM698_RS08170	COG0300	oxidoreductase activity
IM698_RS08175	COG1090	epimerase
IM698_RS08200	COG0622	Phosphoesterase
IM698_RS08215	COG3710	Transcriptional regulator
IM698_RS08220	COG0326	Molecular chaperone. Has ATPase activity
IM698_RS08225	COG0563	adenylate kinase activity
IM698_RS08230	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
IM698_RS08235	COG3104	oligopeptide transport
IM698_RS08245	COG0367	asparagine synthase
IM698_RS08250	COG4651	solute:proton antiporter activity
IM698_RS08250	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IM698_RS08255	COG1846	Transcriptional regulator
IM698_RS08255	COG1940	carbohydrate kinase activity
IM698_RS08260	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
IM698_RS08265	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IM698_RS08265	COG1263	PTS System
IM698_RS08265	COG2190	(PTS) system
IM698_RS08270	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IM698_RS08295	COG0596	Alpha beta hydrolase
IM698_RS08300	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
IM698_RS08305	COG0033	Phosphoglucomutase
IM698_RS08315	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IM698_RS08330	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
IM698_RS08335	COG1053	succinate dehydrogenase
IM698_RS08340	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IM698_RS08345	COG0567	Dehydrogenase, E1 component
IM698_RS08350	COG0508	dehydrogenase complex catalyzes the overall conversion of
IM698_RS08355	COG0045	succinate-CoA ligase (ADP-forming) activity
IM698_RS08365	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IM698_RS08370	COG1121	(ABC) transporter
IM698_RS08375	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
IM698_RS08385	COG1918	ferrous iron import across plasma membrane
IM698_RS08405	COG0018	arginyl-trna synthetase
IM698_RS08410	COG3102	Protein conserved in bacteria
IM698_RS08415	COG0788	formyltetrahydrofolate deformylase activity
IM698_RS08425	COG1199	ATP-dependent helicase activity
IM698_RS08430	COG1214	PFAM Peptidase M22, glycoprotease
IM698_RS08445	COG0596	Alpha beta hydrolase
IM698_RS08450	COG0318	PFAM AMP-dependent synthetase and ligase
IM698_RS08455	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
IM698_RS08460	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
IM698_RS08465	COG2894	cell division
IM698_RS08470	COG0850	regulation of cytokinetic process
IM698_RS08475	COG3100	YcgL domain-containing protein
IM698_RS08480	COG2951	lytic endotransglycosylase activity
IM698_RS08485	COG0583	DNA-binding transcription factor activity
IM698_RS08490	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IM698_RS08500	COG2801	Transposase and inactivated derivatives
IM698_RS08505	COG2963	transposase activity
IM698_RS08510	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IM698_RS08520	COG0515	serine threonine protein kinase
IM698_RS08520	COG2815	serine threonine protein kinase
IM698_RS08535	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IM698_RS08545	COG2860	membrane
IM698_RS08550	COG3101	peptidyl-lysine hydroxylation
IM698_RS08570	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IM698_RS08575	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IM698_RS08580	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IM698_RS08590	COG0101	tRNA pseudouridine synthase activity
IM698_RS08595	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IM698_RS08600	COG0285	dihydrofolate synthase activity
IM698_RS08605	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
IM698_RS08610	COG1286	toxin biosynthetic process
IM698_RS08615	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IM698_RS08620	COG0583	DNA-binding transcription factor activity
IM698_RS08625	COG0745	RESPONSE REGULATOR receiver
IM698_RS08635	COG2832	Protein of unknown function (DUF454)
IM698_RS08640	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IM698_RS08645	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IM698_RS08650	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IM698_RS08655	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IM698_RS08670	COG2983	Belongs to the UPF0260 family
IM698_RS08690	COG2226	methyltransferase
IM698_RS08705	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IM698_RS08710	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IM698_RS08720	COG3139	Protein of unknown function (DUF1315)
IM698_RS08725	COG0252	asparaginase activity
IM698_RS08730	COG0616	signal peptide processing
IM698_RS08735	COG0446	pyridine nucleotide-disulphide oxidoreductase
IM698_RS08735	COG1902	pentaerythritol trinitrate reductase activity
IM698_RS08740	COG0778	Nitroreductase
IM698_RS08745	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IM698_RS08760	COG0123	including yeast histone deacetylase and acetoin utilization protein
IM698_RS08855	COG0745	RESPONSE REGULATOR receiver
IM698_RS08860	COG2205	protein histidine kinase activity
IM698_RS08910	COG0582	viral genome integration into host DNA
IM698_RS08945	COG3082	Protein of unknown function (DUF1414)
IM698_RS08950	COG3081	Nucleoid-associated protein
IM698_RS08965	COG1757	Na H antiporter
IM698_RS08970	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IM698_RS08975	COG2165	general secretion pathway protein
IM698_RS08980	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IM698_RS08985	COG2095	MarC family integral membrane protein
IM698_RS08990	COG1012	belongs to the aldehyde dehydrogenase family
IM698_RS08990	COG1454	alcohol dehydrogenase
IM698_RS09010	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
IM698_RS09020	COG2056	Na+-H+ antiporter family
IM698_RS09025	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IM698_RS09040	COG0346	lactoylglutathione lyase activity
IM698_RS09045	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IM698_RS09050	COG4660	Part of a membrane complex involved in electron transport
IM698_RS09055	COG4659	FMN binding
IM698_RS09060	COG4658	electron transport chain
IM698_RS09065	COG4656	Part of a membrane complex involved in electron transport
IM698_RS09070	COG2878	Part of a membrane complex involved in electron transport
IM698_RS09075	COG4657	Part of a membrane complex involved in electron transport
IM698_RS09080	COG1609	Transcriptional regulator
IM698_RS09085	COG3250	beta-galactosidase activity
IM698_RS09095	COG4580	involved in the transport of maltose and maltodextrins
IM698_RS09105	COG2211	Major facilitator Superfamily
IM698_RS09115	COG0556	nucleotide-excision repair
IM698_RS09120	COG2204	response regulator
IM698_RS09125	COG2198	Histidine kinase
IM698_RS09130	COG0391	Required for morphogenesis under gluconeogenic growth conditions
IM698_RS09135	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IM698_RS09140	COG0521	Mo-molybdopterin cofactor biosynthetic process
IM698_RS09145	COG0315	cyclic pyranopterin monophosphate synthase activity
IM698_RS09150	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
IM698_RS09155	COG0314	molybdopterin synthase activity
IM698_RS09165	COG0601	transmembrane transport
IM698_RS09170	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IM698_RS09175	COG0444	Belongs to the ABC transporter superfamily
IM698_RS09185	COG0435	Glutathione S-transferase
IM698_RS09190	COG0280	phosphate acetyltransferase
IM698_RS09190	COG0857	belongs to the CobB CobQ family
IM698_RS09195	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IM698_RS09200	COG3092	negative regulation of chromosome organization
IM698_RS09210	COG3706	GGDEF domain
IM698_RS09215	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IM698_RS09220	COG0653	protein targeting
IM698_RS09225	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
IM698_RS09230	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
IM698_RS09235	COG2186	Transcriptional regulator
IM698_RS09245	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IM698_RS09245	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IM698_RS09250	COG0489	protein tyrosine kinase activity
IM698_RS09255	COG0572	uridine kinase
IM698_RS09260	COG2982	Protein involved in outer membrane biogenesis
IM698_RS09265	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
IM698_RS09270	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IM698_RS09275	COG0659	secondary active sulfate transmembrane transporter activity
IM698_RS09280	COG1530	ribonuclease E activity
IM698_RS09285	COG0564	pseudouridine synthase activity
IM698_RS09295	COG1399	metal-binding, possibly nucleic acid-binding protein
IM698_RS09300	COG0333	Belongs to the bacterial ribosomal protein bL32 family
IM698_RS09305	COG0416	fatty acid biosynthetic process
IM698_RS09310	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IM698_RS09335	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IM698_RS09340	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IM698_RS09355	COG0084	hydrolase, TatD family'
IM698_RS09375	COG4667	esterase of the alpha-beta hydrolase superfamily
IM698_RS09380	COG0469	pyruvate kinase activity
IM698_RS09385	COG1940	carbohydrate kinase activity
IM698_RS09390	COG0784	Response regulator, receiver
IM698_RS09390	COG0835	chemotaxis
IM698_RS09405	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IM698_RS09410	COG1028	Short-chain dehydrogenase reductase Sdr
IM698_RS09415	COG0616	signal peptide processing
IM698_RS09420	COG2719	SpoVR family
IM698_RS09425	COG2718	Belongs to the UPF0229 family
IM698_RS09430	COG2766	serine protein kinase
IM698_RS09440	COG3013	Belongs to the UPF0304 family
IM698_RS09445	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IM698_RS09455	COG1882	Formate acetyltransferase
IM698_RS09485	COG4160	amino acid transport
IM698_RS09495	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IM698_RS09505	COG0708	Exodeoxyribonuclease III
IM698_RS09510	COG1770	oligopeptidase
IM698_RS09515	COG2814	Major facilitator Superfamily
IM698_RS09520	COG0840	transmembrane signaling receptor activity
IM698_RS09525	COG2850	peptidyl-arginine hydroxylation
IM698_RS09545	COG1199	ATP-dependent helicase activity
IM698_RS09555	COG1187	pseudouridine synthase activity
IM698_RS09565	COG1278	Cold shock
IM698_RS09570	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
IM698_RS09575	COG0542	response to heat
IM698_RS09580	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IM698_RS09585	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
IM698_RS09590	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
IM698_RS09600	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
IM698_RS09610	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IM698_RS09615	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
IM698_RS09620	COG0297	glycogen (starch) synthase activity
IM698_RS09640	COG3070	regulator of competence-specific genes
IM698_RS09645	COG1609	Transcriptional regulator
IM698_RS09650	COG3381	protein complex oligomerization
IM698_RS09655	COG0745	RESPONSE REGULATOR receiver
IM698_RS09660	COG1434	Gram-negative-bacterium-type cell wall biogenesis
IM698_RS09665	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IM698_RS09670	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
IM698_RS09675	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
IM698_RS09680	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
IM698_RS09685	COG3385	transposase activity
IM698_RS09690	COG3383	formate dehydrogenase (NAD+) activity
IM698_RS09705	COG0189	ligase activity
IM698_RS09705	COG4067	protein conserved in archaea
IM698_RS09710	COG0500	methyltransferase
IM698_RS09715	COG4106	trans-aconitate 2-methyltransferase activity
IM698_RS09720	COG1801	Protein of unknown function DUF72
IM698_RS09725	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
IM698_RS09730	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
IM698_RS09740	COG0632	four-way junction helicase activity
IM698_RS09745	COG2255	four-way junction helicase activity
IM698_RS09750	COG1271	oxidase subunit
IM698_RS09755	COG1294	oxidase, subunit
IM698_RS09760	COG4890	Cyd operon protein YbgT
IM698_RS09770	COG0824	Thioesterase
IM698_RS09775	COG0811	peptide transport
IM698_RS09790	COG0823	Involved in the tonB-independent uptake of proteins
IM698_RS09795	COG2885	chlorophyll binding
IM698_RS09800	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
IM698_RS09805	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
IM698_RS09820	COG0784	Response regulator, receiver
IM698_RS09820	COG5002	protein histidine kinase activity
IM698_RS09835	COG0786	glutamate:sodium symporter activity
IM698_RS09840	COG1349	DNA-binding transcription factor activity
IM698_RS09860	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
IM698_RS09870	COG0583	DNA-binding transcription factor activity
IM698_RS09875	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IM698_RS09895	COG0745	RESPONSE REGULATOR receiver
IM698_RS09900	COG0463	Glycosyl transferase, family 2
IM698_RS09915	COG3135	benzoate transporter
IM698_RS09920	COG1396	sequence-specific DNA binding
IM698_RS09925	COG1032	radical SAM domain protein
IM698_RS09940	COG0583	DNA-binding transcription factor activity
IM698_RS09945	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IM698_RS09955	COG2350	Protein conserved in bacteria
IM698_RS09960	COG1607	acyl-coa hydrolase
IM698_RS09965	COG2917	probably involved in intracellular septation
IM698_RS09975	COG0583	DNA-binding transcription factor activity
IM698_RS09985	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IM698_RS09995	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
IM698_RS10005	COG1301	dicarboxylic acid transport
IM698_RS10010	COG0159	tryptophan synthase activity
IM698_RS10015	COG0133	tryptophan synthase activity
IM698_RS10020	COG0135	phosphoribosylanthranilate isomerase activity
IM698_RS10020	COG0134	indole-3-glycerol-phosphate synthase activity
IM698_RS10025	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IM698_RS10030	COG0512	Glutamine amidotransferase of anthranilate synthase
IM698_RS10035	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IM698_RS10045	COG0613	PHP domain protein
IM698_RS10050	COG0009	L-threonylcarbamoyladenylate synthase
IM698_RS10055	COG1187	pseudouridine synthase activity
IM698_RS10070	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IM698_RS10080	COG0417	DNA replication proofreading
IM698_RS10085	COG2197	response regulator
IM698_RS10090	COG0322	excinuclease ABC activity
IM698_RS10130	COG0019	diaminopimelate decarboxylase activity
IM698_RS10150	COG3302	dmso reductase anchor subunit
IM698_RS10155	COG0437	4 iron, 4 sulfur cluster binding
IM698_RS10160	COG0243	molybdopterin cofactor binding
IM698_RS10165	COG3381	protein complex oligomerization
IM698_RS10180	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IM698_RS10185	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IM698_RS10190	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IM698_RS10210	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
IM698_RS10220	COG0437	4 iron, 4 sulfur cluster binding
IM698_RS10225	COG3301	Polysulphide reductase, NrfD
IM698_RS10230	COG1138	Cytochrome C-type biogenesis protein
IM698_RS10240	COG3088	subunit of a heme lyase
IM698_RS10240	COG4235	cytochrome complex assembly
IM698_RS10250	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IM698_RS10275	COG2989	Protein conserved in bacteria
IM698_RS10280	COG3108	Peptidase M15
IM698_RS10285	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IM698_RS10300	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
IM698_RS10325	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IM698_RS10330	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IM698_RS10335	COG0840	transmembrane signaling receptor activity
IM698_RS10340	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
IM698_RS10345	COG4988	ABC transporter
IM698_RS10350	COG0492	ferredoxin-NADP+ reductase activity
IM698_RS10370	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IM698_RS10385	COG2199	diguanylate cyclase activity
IM698_RS10385	COG2203	Gaf domain
IM698_RS10400	COG0471	metal ion transport
IM698_RS10405	COG2949	membrane
IM698_RS10410	COG0281	malic enzyme
IM698_RS10415	COG1643	Atp-dependent helicase
IM698_RS10425	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
IM698_RS10460	COG0247	lactate metabolic process
IM698_RS10460	COG0277	FAD linked oxidase domain protein
IM698_RS10475	COG2986	histidine ammonia-lyase
IM698_RS10480	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
IM698_RS10485	COG0010	Belongs to the arginase family
IM698_RS10490	COG1228	amidohydrolase
IM698_RS10500	COG4326	sporulation control protein
IM698_RS10520	COG0291	Belongs to the bacterial ribosomal protein bL35 family
IM698_RS10525	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IM698_RS10530	COG3097	Belongs to the UPF0267 family
IM698_RS10545	COG0488	(ABC) transporter
IM698_RS10550	COG1309	transcriptional regulator
IM698_RS10560	COG1166	arginine decarboxylase activity
IM698_RS10565	COG0010	Belongs to the arginase family
IM698_RS10575	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
IM698_RS10580	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IM698_RS10585	COG0800	Aldolase
IM698_RS10590	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IM698_RS10595	COG1917	Cupin 2, conserved barrel domain protein
IM698_RS10620	COG3639	organic phosphonate transmembrane transporter activity
IM698_RS10625	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
IM698_RS10635	COG2186	Transcriptional regulator
IM698_RS10650	COG3181	Tripartite tricarboxylate transporter family receptor
IM698_RS10660	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IM698_RS10675	COG0840	transmembrane signaling receptor activity
IM698_RS10710	COG2186	Transcriptional regulator
IM698_RS10715	COG1028	Short-chain dehydrogenase reductase Sdr
IM698_RS10720	COG2186	Transcriptional regulator
IM698_RS10725	COG0517	IMP dehydrogenase activity
IM698_RS10730	COG2176	DNA-directed DNA polymerase activity
IM698_RS10750	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IM698_RS10775	COG3033	Beta-eliminating lyase
IM698_RS10820	COG0471	metal ion transport
IM698_RS10825	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IM698_RS10825	COG4191	Histidine kinase
IM698_RS10850	COG0454	-acetyltransferase
IM698_RS10865	COG0730	response to heat
IM698_RS10880	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
IM698_RS10885	COG1280	lysine exporter protein (LysE YggA)
IM698_RS10890	COG1115	amino acid carrier protein
IM698_RS10940	COG1115	amino acid carrier protein
IM698_RS10955	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IM698_RS10970	COG3290	protein histidine kinase activity
IM698_RS10975	COG4565	transcriptional regulatory protein
IM698_RS10980	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IM698_RS10985	COG0363	glucosamine-6-phosphate deaminase activity
IM698_RS10990	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IM698_RS11000	COG4628	conserved protein (DUF2132)
IM698_RS11035	COG3437	response regulator, receiver
IM698_RS11045	COG0515	serine threonine protein kinase
IM698_RS11150	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
IM698_RS11160	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
IM698_RS11165	COG0372	Belongs to the citrate synthase family
IM698_RS11170	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IM698_RS11205	COG0561	phosphatase activity
IM698_RS11210	COG0602	queuosine metabolic process
IM698_RS11215	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
IM698_RS11220	COG3706	GGDEF domain
IM698_RS11230	COG2885	chlorophyll binding
IM698_RS11255	COG1254	Belongs to the acylphosphatase family
IM698_RS11260	COG2920	part of a sulfur-relay system
IM698_RS11265	COG0670	Belongs to the BI1 family
IM698_RS11270	COG1126	abc transporter atp-binding protein
IM698_RS11275	COG0765	amino acid transport
IM698_RS11280	COG4597	amino acid ABC transporter
IM698_RS11285	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IM698_RS11295	COG1666	GTP binding
IM698_RS11300	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IM698_RS11305	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IM698_RS11305	COG0574	Belongs to the PEP-utilizing enzyme family
IM698_RS11320	COG2996	Protein conserved in bacteria
IM698_RS11325	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IM698_RS11325	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
IM698_RS11330	COG3008	intermembrane lipid transfer
IM698_RS11335	COG2995	paraquat-inducible protein a
IM698_RS11340	COG1132	(ABC) transporter
IM698_RS11345	COG1956	GAF domain-containing protein
IM698_RS11350	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
IM698_RS11365	COG0308	aminopeptidase N
IM698_RS11375	COG2902	Dehydrogenase
IM698_RS11380	COG0167	dihydroorotate dehydrogenase activity
IM698_RS11390	COG0116	Belongs to the methyltransferase superfamily
IM698_RS11390	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
IM698_RS11400	COG0488	(ABC) transporter
IM698_RS11420	COG1067	ATP-dependent peptidase activity
IM698_RS11425	COG3120	sequence-specific DNA binding
IM698_RS11455	COG0784	Response regulator, receiver
IM698_RS11455	COG2205	protein histidine kinase activity
IM698_RS11470	COG3278	Belongs to the heme-copper respiratory oxidase family
IM698_RS11485	COG2010	Cytochrome c
IM698_RS11495	COG2217	Heavy metal translocating P-type atpase
IM698_RS11510	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IM698_RS11515	COG0589	response to stress
IM698_RS11520	COG0037	tRNA processing
IM698_RS11540	COG3842	ATPase activity
IM698_RS11550	COG1177	transmembrane transport
IM698_RS11560	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
IM698_RS11565	COG2199	diguanylate cyclase activity
IM698_RS11565	COG2203	Gaf domain
IM698_RS11570	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IM698_RS11575	COG0004	ammonium transporteR
IM698_RS11590	COG0437	4 iron, 4 sulfur cluster binding
IM698_RS11595	COG0243	molybdopterin cofactor binding
IM698_RS11595	COG3383	formate dehydrogenase (NAD+) activity
IM698_RS11605	COG3381	protein complex oligomerization
IM698_RS11625	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
IM698_RS11640	COG3220	belongs to the UPF0276 family
IM698_RS11655	COG1271	oxidase subunit
IM698_RS11660	COG1294	oxidase, subunit
IM698_RS11670	COG0488	(ABC) transporter
IM698_RS11685	COG4191	Histidine kinase
IM698_RS11690	COG2204	response regulator
IM698_RS11700	COG4662	Binding-protein-dependent transport system inner membrane component
IM698_RS11705	COG3842	ATPase activity
IM698_RS11710	COG0746	molybdenum cofactor guanylyltransferase activity
IM698_RS11715	COG0303	'Molybdopterin
IM698_RS11725	COG1940	carbohydrate kinase activity
IM698_RS11730	COG3148	PFAM DTW domain containing protein
IM698_RS11740	COG0840	transmembrane signaling receptor activity
IM698_RS11745	COG0791	NLP P60 protein
IM698_RS11755	COG3001	Fructosamine kinase
IM698_RS11765	COG0307	riboflavin synthase, alpha
IM698_RS11770	COG0534	Mate efflux family protein
IM698_RS11775	COG1793	dna ligase
IM698_RS11805	COG4176	ABC-type proline glycine betaine transport system permease component
IM698_RS11810	COG3448	diguanylate cyclase activity
IM698_RS11810	COG4175	Glycine betaine
IM698_RS11820	COG2204	response regulator
IM698_RS11855	COG0840	transmembrane signaling receptor activity
IM698_RS11910	COG2871	sodium ion transport
IM698_RS11915	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
IM698_RS11930	COG3118	belongs to the thioredoxin family
IM698_RS11935	COG0513	Belongs to the DEAD box helicase family
IM698_RS11940	COG0248	Ppx GppA phosphatase
IM698_RS11945	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
IM698_RS11955	COG0514	ATP-dependent DNA helicase (RecQ)
IM698_RS11960	COG2962	Rard protein
IM698_RS11970	COG1280	lysine exporter protein (LysE YggA)
IM698_RS11975	COG0405	Gamma-glutamyltransferase
IM698_RS11985	COG0210	DNA helicase
IM698_RS11995	COG3220	belongs to the UPF0276 family
IM698_RS12025	COG0006	proline dipeptidase activity
IM698_RS12025	COG0006	proline dipeptidase activity
IM698_RS12035	COG2022	thiamine diphosphate biosynthetic process
IM698_RS12040	COG2104	thiamine diphosphate biosynthetic process
IM698_RS12045	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
IM698_RS12050	COG0352	thiamine-phosphate diphosphorylase activity
IM698_RS12055	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
IM698_RS12065	COG2132	Multicopper oxidase
IM698_RS12110	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IM698_RS12120	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IM698_RS12125	COG0408	coproporphyrinogen oxidase activity
IM698_RS12130	COG0009	L-threonylcarbamoyladenylate synthase
IM698_RS12135	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IM698_RS12140	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IM698_RS12145	COG0551	DNA topoisomerase type I activity
IM698_RS12150	COG2922	Belongs to the Smg family
IM698_RS12155	COG0758	DNA mediated transformation
IM698_RS12170	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IM698_RS12175	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IM698_RS12175	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IM698_RS12180	COG0569	domain protein
IM698_RS12185	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IM698_RS12195	COG1272	protein, Hemolysin III
IM698_RS12200	COG4326	sporulation control protein
IM698_RS12210	COG3084	Protein conserved in bacteria
IM698_RS12220	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IM698_RS12225	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IM698_RS12235	COG0606	chelatase, subunit chli
IM698_RS12245	COG3978	acetolactate synthase activity
IM698_RS12250	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IM698_RS12255	COG0129	dihydroxy-acid dehydratase activity
IM698_RS12265	COG0583	DNA-binding transcription factor activity
IM698_RS12270	COG2814	Major facilitator Superfamily
IM698_RS12280	COG0355	proton-transporting ATP synthase activity, rotational mechanism
IM698_RS12285	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IM698_RS12290	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IM698_RS12295	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IM698_RS12300	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IM698_RS12305	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IM698_RS12320	COG3312	ion transport
IM698_RS12325	COG1475	DNA binding
IM698_RS12330	COG1192	Involved in chromosome partitioning
IM698_RS12335	COG0357	Ribosomal RNA small subunit methyltransferase G
IM698_RS12340	COG0445	tRNA wobble uridine modification
IM698_RS12345	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IM698_RS12355	COG0706	membrane insertase activity
IM698_RS12360	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
IM698_RS12365	COG0594	ribonuclease P activity
IM698_RS12370	COG0230	Belongs to the bacterial ribosomal protein bL34 family
IM698_RS12375	COG1126	abc transporter atp-binding protein
IM698_RS12390	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IM698_RS12395	COG0592	DNA-directed DNA polymerase activity
IM698_RS12400	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IM698_RS12405	COG0187	DNA topoisomerase II activity
IM698_RS12415	COG3977	Valine--pyruvate aminotransferase
IM698_RS12420	COG0366	Alpha amylase catalytic
IM698_RS12425	COG0751	glycine-tRNA ligase activity
IM698_RS12430	COG0752	glycyl-tRNA synthetase alpha subunit
IM698_RS12435	COG2119	membrane
IM698_RS12445	COG0425	Belongs to the sulfur carrier protein TusA family
IM698_RS12460	COG0604	alcohol dehydrogenase
IM698_RS12465	COG0183	Belongs to the thiolase family
IM698_RS12470	COG1024	Enoyl-CoA hydratase
IM698_RS12470	COG1250	3-hydroxyacyl-CoA dehydrogenase
IM698_RS12475	COG1739	Uncharacterized protein family UPF0029
IM698_RS12480	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IM698_RS12530	COG0583	DNA-binding transcription factor activity
IM698_RS12535	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IM698_RS12540	COG2960	long-chain fatty acid transporting porin activity
IM698_RS12545	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IM698_RS12550	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IM698_RS12555	COG1309	transcriptional regulator
IM698_RS12605	COG0601	transmembrane transport
IM698_RS12610	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IM698_RS12645	COG1805	sodium ion transport
IM698_RS12655	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IM698_RS12660	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
IM698_RS12670	COG1522	sequence-specific DNA binding
IM698_RS12680	COG0742	ribosomal rna small subunit methyltransferase
IM698_RS12695	COG0589	response to stress
IM698_RS12700	COG1528	Iron-storage protein
IM698_RS12710	COG2081	HI0933 family
IM698_RS12720	COG1322	Protein conserved in bacteria
IM698_RS12725	COG2226	methyltransferase
IM698_RS12730	COG3165	ubiquinone biosynthetic process from chorismate
IM698_RS12735	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
IM698_RS12740	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IM698_RS12745	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IM698_RS12750	COG0805	protein transport
IM698_RS12755	COG0084	hydrolase, TatD family'
IM698_RS12770	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IM698_RS12770	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IM698_RS12795	COG3078	GTPase activator activity
IM698_RS12820	COG3852	Histidine kinase
IM698_RS12830	COG0174	glutamine synthetase
IM698_RS12835	COG1217	gtp-binding protein TYPA
IM698_RS12850	COG1295	ribonuclease BN
IM698_RS12855	COG1490	D-aminoacyl-tRNA deacylase activity
IM698_RS12860	COG0456	acetyltransferase
IM698_RS12870	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
IM698_RS12880	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
IM698_RS12885	COG3031	protein transport across the cell outer membrane
IM698_RS12895	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IM698_RS12900	COG1459	type II secretion system
IM698_RS12905	COG2165	general secretion pathway protein
IM698_RS12910	COG2165	general secretion pathway protein
IM698_RS12915	COG2165	general secretion pathway protein
IM698_RS12920	COG4795	General secretion pathway protein
IM698_RS12925	COG3156	type II secretion system protein K
IM698_RS12930	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
IM698_RS12935	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
IM698_RS12945	COG1218	3'(2'),5'-bisphosphate nucleotidase
IM698_RS12950	COG0494	nUDIX hydrolase
IM698_RS12955	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
IM698_RS12955	COG0316	Belongs to the HesB IscA family
IM698_RS12960	COG1040	competence protein
IM698_RS12965	COG0596	Alpha beta hydrolase
IM698_RS12975	COG2183	response to ionizing radiation
IM698_RS12980	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IM698_RS12995	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IM698_RS13000	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IM698_RS13005	COG1758	RNA polymerase activity
IM698_RS13010	COG0194	GDP metabolic process
IM698_RS13015	COG2252	PERMEase
IM698_RS13025	COG1278	Cold shock
IM698_RS13030	COG1561	YicC-like family, N-terminal region
IM698_RS13035	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
IM698_RS13040	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IM698_RS13045	COG1560	Kdo2-lipid A biosynthetic process
IM698_RS13050	COG1309	transcriptional regulator
IM698_RS13060	COG2003	Belongs to the UPF0758 family
IM698_RS13065	COG0227	Belongs to the bacterial ribosomal protein bL28 family
IM698_RS13070	COG0267	Belongs to the bacterial ribosomal protein bL33 family
IM698_RS13080	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
IM698_RS13095	COG0438	transferase activity, transferring glycosyl groups
IM698_RS13100	COG0463	Glycosyl transferase, family 2
IM698_RS13105	COG0859	PFAM glycosyl transferase family 9
IM698_RS13110	COG3642	lipopolysaccharide core region biosynthetic process
IM698_RS13130	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IM698_RS13160	COG1051	belongs to the nudix hydrolase family
IM698_RS13175	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
IM698_RS13195	COG1519	Transferase
IM698_RS13200	COG0859	PFAM glycosyl transferase family 9
IM698_RS13205	COG1560	Kdo2-lipid A biosynthetic process
IM698_RS13225	COG4942	peptidase
IM698_RS13230	COG1045	serine acetyltransferase
IM698_RS13240	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
IM698_RS13245	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IM698_RS13280	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
IM698_RS13285	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
IM698_RS13290	COG2089	acid synthase
IM698_RS13295	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IM698_RS13300	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
IM698_RS13305	COG1083	cytidylyl-transferase
IM698_RS13310	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
IM698_RS13320	COG1028	Short-chain dehydrogenase reductase Sdr
IM698_RS13345	COG1215	transferase activity, transferring glycosyl groups
IM698_RS13355	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
IM698_RS13405	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IM698_RS13425	COG0534	Mate efflux family protein
IM698_RS13430	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IM698_RS13445	COG3706	GGDEF domain
IM698_RS13450	COG1285	pathogenesis
IM698_RS13455	COG1509	lysine 2,3-aminomutase activity
IM698_RS13460	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IM698_RS13470	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
IM698_RS13475	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IM698_RS13480	COG1053	succinate dehydrogenase
IM698_RS13485	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
IM698_RS13495	COG0840	transmembrane signaling receptor activity
IM698_RS13500	COG0471	metal ion transport
IM698_RS13500	COG0490	domain, Protein
IM698_RS13505	COG0688	phosphatidylethanolamine metabolic process
IM698_RS13510	COG1162	GTPase activity
IM698_RS13595	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IM698_RS13600	COG0802	atpase or kinase
IM698_RS13605	COG0860	N-Acetylmuramoyl-L-alanine amidase
IM698_RS13610	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IM698_RS13615	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IM698_RS13620	COG1923	regulation of RNA biosynthetic process
IM698_RS13625	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IM698_RS13630	COG0330	HflC and HflK could
IM698_RS13635	COG0330	HflC and HflK could
IM698_RS13640	COG3385	transposase activity
IM698_RS13645	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
IM698_RS13650	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IM698_RS13655	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
IM698_RS13660	COG0402	S-adenosylhomocysteine deaminase activity
IM698_RS13665	COG0557	exoribonuclease II activity
IM698_RS13670	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IM698_RS13675	COG0360	Binds together with S18 to 16S ribosomal RNA
IM698_RS13685	COG0359	binds to the 23S rRNA
IM698_RS13700	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IM698_RS13710	COG0432	Pfam Uncharacterised protein family UPF0047
IM698_RS13715	COG0166	Belongs to the GPI family
IM698_RS13730	COG0735	belongs to the Fur family
IM698_RS13740	COG0583	DNA-binding transcription factor activity
IM698_RS13785	COG0582	viral genome integration into host DNA
IM698_RS13795	COG3081	Nucleoid-associated protein
IM698_RS13865	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IM698_RS13870	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IM698_RS13875	COG0175	sulfate reduction
IM698_RS13885	COG3071	HemY protein
IM698_RS13890	COG2959	enzyme of heme biosynthesis
IM698_RS13895	COG1587	Uroporphyrinogen-III synthase
IM698_RS13900	COG0181	hydroxymethylbilane synthase activity
IM698_RS13905	COG3072	Adenylate cyclase
IM698_RS13910	COG1965	Belongs to the frataxin family
IM698_RS13920	COG0019	diaminopimelate decarboxylase activity
IM698_RS13925	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
IM698_RS13935	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
IM698_RS13940	COG1011	Hydrolase
IM698_RS13945	COG3287	FIST C domain
IM698_RS13945	COG2200	EAL domain
IM698_RS13945	COG2199	diguanylate cyclase activity
IM698_RS13950	COG3287	FIST C domain
IM698_RS13950	COG2200	EAL domain
IM698_RS13950	COG2199	diguanylate cyclase activity
IM698_RS13955	COG3148	PFAM DTW domain containing protein
IM698_RS13970	COG0561	phosphatase activity
IM698_RS13975	COG2267	carboxylic ester hydrolase activity
IM698_RS13980	COG1280	lysine exporter protein (LysE YggA)
IM698_RS13985	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
IM698_RS13990	COG0640	Transcriptional regulator
IM698_RS13995	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IM698_RS14035	COG2095	MarC family integral membrane protein
IM698_RS14045	COG0742	ribosomal rna small subunit methyltransferase
IM698_RS14050	COG0552	protein localization to endoplasmic reticulum
IM698_RS14055	COG2884	Cell division ATP-binding protein ftsE
IM698_RS14060	COG2177	Part of the ABC transporter FtsEX involved in
IM698_RS14070	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IM698_RS14075	COG0705	Rhomboid family
IM698_RS14080	COG1580	Controls the rotational direction of flagella during chemotaxis
IM698_RS14085	COG3161	chorismate lyase activity
IM698_RS14090	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
IM698_RS14095	COG2937	Belongs to the GPAT DAPAT family
IM698_RS14100	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
IM698_RS14105	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IM698_RS14110	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
IM698_RS14115	COG0534	Mate efflux family protein
IM698_RS14120	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IM698_RS14135	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IM698_RS14140	COG4206	TonB-dependent receptor
IM698_RS14150	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
IM698_RS14165	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IM698_RS14175	COG0812	UDP-N-acetylmuramate dehydrogenase activity
IM698_RS14185	COG1072	(Pantothenic acid kinase))
IM698_RS14215	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
IM698_RS14220	COG0250	Participates in transcription elongation, termination and antitermination
IM698_RS14230	COG0081	regulation of translation
IM698_RS14235	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IM698_RS14240	COG0222	ribosome binding
IM698_RS14255	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
IM698_RS14260	COG2816	NAD+ diphosphatase activity
IM698_RS14270	COG1573	uracil-dna glycosylase
IM698_RS14280	COG3068	Protein conserved in bacteria
IM698_RS14285	COG1253	flavin adenine dinucleotide binding
IM698_RS14300	COG0151	Belongs to the GarS family
IM698_RS14305	COG0138	bifunctional purine biosynthesis protein purh
IM698_RS14310	COG0789	Transcriptional regulator
IM698_RS14315	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
IM698_RS14320	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IM698_RS14325	COG2264	protein methyltransferase activity
IM698_RS14330	COG0439	Biotin carboxylase
IM698_RS14335	COG0511	ligase activity, forming carbon-carbon bonds
IM698_RS14340	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
IM698_RS14345	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IM698_RS14360	COG2814	Major facilitator Superfamily
IM698_RS14365	COG0784	Response regulator, receiver
IM698_RS14365	COG2198	Histidine kinase
IM698_RS14365	COG2205	protein histidine kinase activity
IM698_RS14380	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IM698_RS14390	COG3263	regulation of cellular component size
IM698_RS14400	COG4232	protein-disulfide reductase activity
IM698_RS14405	COG1438	arginine binding
IM698_RS14410	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
IM698_RS14415	COG0540	Belongs to the ATCase OTCase family
IM698_RS14420	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IM698_RS14435	COG1288	antiporter activity
IM698_RS14440	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
IM698_RS14445	COG1027	Aspartate ammonia-lyase
IM698_RS14455	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
IM698_RS14465	COG2205	protein histidine kinase activity
IM698_RS14470	COG0745	RESPONSE REGULATOR receiver
IM698_RS14480	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IM698_RS14485	COG0205	6-phosphofructokinase activity
IM698_RS14490	COG0149	triose-phosphate isomerase activity
IM698_RS14500	COG3152	Membrane
IM698_RS14515	COG1494	fructose-1,6-bisphosphatase
IM698_RS14520	COG3074	FtsZ-dependent cytokinesis
IM698_RS14525	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IM698_RS14530	COG1575	Belongs to the MenA family. Type 1 subfamily
IM698_RS14535	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
IM698_RS14540	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
IM698_RS14550	COG1609	Transcriptional regulator
IM698_RS14555	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IM698_RS14560	COG0254	rRNA binding
IM698_RS14565	COG0281	malic enzyme
IM698_RS14570	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
IM698_RS14575	COG0626	cystathionine gamma-synthase activity
IM698_RS14580	COG0460	homoserine dehydrogenase
IM698_RS14580	COG0527	aspartate kinase activity
IM698_RS14585	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
IM698_RS14595	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
IM698_RS14600	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IM698_RS14605	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IM698_RS14620	COG0165	Argininosuccinate lyase
IM698_RS14620	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
IM698_RS14630	COG0251	oxidation-reduction process
IM698_RS14635	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IM698_RS14640	COG0678	peroxiredoxin activity
IM698_RS14640	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IM698_RS14655	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
IM698_RS14690	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IM698_RS14700	COG0338	D12 class N6 adenine-specific DNA methyltransferase
IM698_RS14705	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
IM698_RS14710	COG0546	phosphoglycolate phosphatase activity
IM698_RS14715	COG0180	Tryptophanyl-tRNA synthetase
IM698_RS14725	COG0512	Glutamine amidotransferase of anthranilate synthase
IM698_RS14730	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IM698_RS14740	COG1012	belongs to the aldehyde dehydrogenase family
IM698_RS14750	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IM698_RS14755	COG3954	Phosphoribulokinase
IM698_RS14760	COG3089	Belongs to the UPF0270 family
IM698_RS14765	COG0429	hydrolase of the alpha beta-hydrolase fold
IM698_RS14775	COG0488	(ABC) transporter
IM698_RS14780	COG2249	NAD(P)H dehydrogenase (quinone) activity
IM698_RS14795	COG1047	Peptidyl-prolyl cis-trans
IM698_RS14800	COG1446	asparaginase
IM698_RS14805	COG2900	Belongs to the SlyX family
IM698_RS14815	COG0545	Peptidyl-prolyl cis-trans isomerase
IM698_RS14820	COG2964	Protein conserved in bacteria
IM698_RS14825	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
IM698_RS14830	COG2923	Belongs to the DsrF TusC family
IM698_RS14850	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IM698_RS14865	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IM698_RS14870	COG0088	Forms part of the polypeptide exit tunnel
IM698_RS14875	COG0089	rRNA binding
IM698_RS14880	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IM698_RS14885	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IM698_RS14895	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IM698_RS14900	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IM698_RS14910	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IM698_RS14915	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IM698_RS14920	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IM698_RS14925	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IM698_RS14930	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IM698_RS14935	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IM698_RS14940	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IM698_RS14945	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IM698_RS14950	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IM698_RS14955	COG1841	ribosomal large subunit assembly
IM698_RS14960	COG0200	Binds to the 23S rRNA
IM698_RS14965	COG0201	protein transport
IM698_RS14970	COG0257	Belongs to the bacterial ribosomal protein bL36 family
IM698_RS14975	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IM698_RS14980	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IM698_RS14985	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IM698_RS14990	COG0202	RNA polymerase activity
IM698_RS14995	COG0203	ribosomal protein L17
IM698_RS15005	COG0545	Peptidyl-prolyl cis-trans isomerase
IM698_RS15010	COG3266	domain, Protein
IM698_RS15010	COG3061	Opacity-associated protein A
IM698_RS15020	COG2153	protein acetylation
IM698_RS15070	COG0737	Belongs to the 5'-nucleotidase family
IM698_RS15075	COG0175	sulfate reduction
IM698_RS15080	COG2895	sulfate adenylyltransferase (ATP) activity
IM698_RS15085	COG0471	metal ion transport
IM698_RS15085	COG3273	potassium ion transport
IM698_RS15090	COG0529	Catalyzes the synthesis of activated sulfate
IM698_RS15125	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
IM698_RS15135	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IM698_RS15140	COG0729	surface antigen
IM698_RS15145	COG2911	Protein conserved in bacteria
IM698_RS15150	COG2105	PFAM AIG2 family protein
IM698_RS15160	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
IM698_RS15165	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IM698_RS15170	COG0163	prenyltransferase activity
IM698_RS15175	COG4143	(ABC) transporter
IM698_RS15180	COG1178	ABC-type Fe3 transport system permease component
IM698_RS15185	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
IM698_RS15190	COG3028	Belongs to the UPF0307 family
IM698_RS15195	COG0312	modulator of DNA gyrase
IM698_RS15200	COG2239	Acts as a magnesium transporter
IM698_RS15205	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IM698_RS15210	COG1660	Displays ATPase and GTPase activities
IM698_RS15215	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IM698_RS15220	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IM698_RS15230	COG1137	ATPase activity
IM698_RS15235	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
IM698_RS15245	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
IM698_RS15250	COG0517	IMP dehydrogenase activity
IM698_RS15250	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
IM698_RS15260	COG1127	ABC transporter
IM698_RS15265	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IM698_RS15270	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IM698_RS15275	COG2854	intermembrane phospholipid transfer
IM698_RS15285	COG5007	Belongs to the BolA IbaG family
IM698_RS15290	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IM698_RS15295	COG0204	Acyl-transferase
IM698_RS15300	COG0251	oxidation-reduction process
IM698_RS15305	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
IM698_RS15335	COG0456	acetyltransferase
IM698_RS15345	COG0525	valine-tRNA ligase activity
IM698_RS15350	COG2927	DNA polymerase III (CHI subunit)
IM698_RS15355	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IM698_RS15360	COG0795	lipopolysaccharide-transporting ATPase activity
IM698_RS15365	COG0795	lipopolysaccharide-transporting ATPase activity
IM698_RS15455	COG3071	HemY protein
IM698_RS15460	COG2959	enzyme of heme biosynthesis
IM698_RS15465	COG1587	Uroporphyrinogen-III synthase
IM698_RS15470	COG0181	hydroxymethylbilane synthase activity
IM698_RS15475	COG3072	Adenylate cyclase
IM698_RS15480	COG1965	Belongs to the frataxin family
IM698_RS15490	COG0019	diaminopimelate decarboxylase activity
IM698_RS15495	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
IM698_RS15505	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
IM698_RS15510	COG1011	Hydrolase
IM698_RS15515	COG2199	diguanylate cyclase activity
IM698_RS15515	COG2200	EAL domain
IM698_RS15515	COG3287	FIST C domain
IM698_RS15520	COG2199	diguanylate cyclase activity
IM698_RS15520	COG3287	FIST C domain
IM698_RS15520	COG2200	EAL domain
IM698_RS15525	COG3148	PFAM DTW domain containing protein
IM698_RS15540	COG0561	phosphatase activity
IM698_RS15545	COG2267	carboxylic ester hydrolase activity
IM698_RS15550	COG1280	lysine exporter protein (LysE YggA)
IM698_RS15555	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
IM698_RS15560	COG0640	Transcriptional regulator
IM698_RS15565	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IM698_RS15605	COG2095	MarC family integral membrane protein
IM698_RS15615	COG0742	ribosomal rna small subunit methyltransferase
IM698_RS15620	COG0552	protein localization to endoplasmic reticulum
IM698_RS15625	COG2884	Cell division ATP-binding protein ftsE
IM698_RS15630	COG2177	Part of the ABC transporter FtsEX involved in
IM698_RS15640	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IM698_RS15645	COG0705	Rhomboid family
IM698_RS15650	COG1580	Controls the rotational direction of flagella during chemotaxis
IM698_RS15655	COG3161	chorismate lyase activity
IM698_RS15660	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
IM698_RS15665	COG2937	Belongs to the GPAT DAPAT family
IM698_RS15670	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
IM698_RS15675	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IM698_RS15680	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
IM698_RS15685	COG0534	Mate efflux family protein
IM698_RS15690	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IM698_RS15705	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IM698_RS15710	COG4206	TonB-dependent receptor
IM698_RS15720	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
IM698_RS15770	COG0840	transmembrane signaling receptor activity
IM698_RS15820	COG5002	protein histidine kinase activity
IM698_RS15825	COG1881	PFAM PEBP family protein
IM698_RS15835	COG2807	transmembrane transport
IM698_RS15870	COG1280	lysine exporter protein (LysE YggA)
IM698_RS15890	COG0534	Mate efflux family protein
IM698_RS15915	COG0509	glycine decarboxylation via glycine cleavage system
IM698_RS15955	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IM698_RS15960	COG3706	GGDEF domain
IM698_RS15965	COG2759	Belongs to the formate--tetrahydrofolate ligase family
IM698_RS15970	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IM698_RS15985	COG3437	response regulator, receiver
IM698_RS15985	COG0784	Response regulator, receiver
IM698_RS15990	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IM698_RS16000	COG0814	amino acid
IM698_RS16010	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
IM698_RS16015	COG0513	Belongs to the DEAD box helicase family
IM698_RS16040	COG2200	EAL domain
IM698_RS16055	COG3038	cytochrome b561
IM698_RS16060	COG2353	YceI-like domain
IM698_RS16065	COG2116	formate transmembrane transporter activity
IM698_RS16070	COG0583	DNA-binding transcription factor activity
IM698_RS16080	COG3593	DNA synthesis involved in DNA repair
IM698_RS16085	COG0737	Belongs to the 5'-nucleotidase family
IM698_RS16090	COG0861	Integral membrane protein TerC family
IM698_RS16105	COG0513	Belongs to the DEAD box helicase family
IM698_RS16110	COG0729	surface antigen
IM698_RS16115	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
IM698_RS16120	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IM698_RS16140	COG1566	PFAM secretion protein HlyD family protein
IM698_RS16150	COG2985	domain, Protein
IM698_RS16160	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
IM698_RS16175	COG0583	DNA-binding transcription factor activity
IM698_RS16190	COG2267	carboxylic ester hydrolase activity
IM698_RS16195	COG2067	long-chain fatty acid transport protein
IM698_RS16205	COG0501	Belongs to the peptidase M48B family
IM698_RS16210	COG2050	protein possibly involved in aromatic compounds catabolism
IM698_RS16220	COG4533	DNA binding
IM698_RS16250	COG0768	penicillin binding
IM698_RS16260	COG1716	ATPase activity
IM698_RS16260	COG5001	Diguanylate cyclase
IM698_RS16265	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
IM698_RS16275	COG4181	ATPase activity
IM698_RS16280	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
IM698_RS16290	COG1984	allophanate hydrolase subunit 2
IM698_RS16315	COG3300	MHYT domain
IM698_RS16315	COG5001	Diguanylate cyclase
IM698_RS16325	COG1629	transport
IM698_RS16325	COG4771	TonB-dependent receptor
IM698_RS16330	COG0583	DNA-binding transcription factor activity
IM698_RS16335	COG0045	succinate-CoA ligase (ADP-forming) activity
IM698_RS16335	COG1042	CoA-binding domain protein
IM698_RS16335	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IM698_RS16340	COG3266	domain, Protein
IM698_RS16345	COG1181	Belongs to the D-alanine--D-alanine ligase family
IM698_RS16360	COG0023	Translation Initiation Factor
IM698_RS16365	COG3140	Belongs to the UPF0181 family
IM698_RS16390	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
IM698_RS16395	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
IM698_RS16410	COG3706	GGDEF domain
IM698_RS16420	COG3706	GGDEF domain
IM698_RS16420	COG2203	Gaf domain
IM698_RS16420	COG4251	negative regulation of phosphorylation
IM698_RS16420	COG5001	Diguanylate cyclase
IM698_RS16430	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
IM698_RS16435	COG4149	molybdate abc transporter
IM698_RS16440	COG0725	ABC transporter, periplasmic molybdate-binding protein
IM698_RS16460	COG0488	(ABC) transporter
IM698_RS16465	COG4067	protein conserved in archaea
IM698_RS16465	COG0189	ligase activity
IM698_RS16475	COG0602	queuosine metabolic process
IM698_RS16480	COG1328	CTP reductase activity
IM698_RS16490	COG2391	methyltransferase activity
IM698_RS16510	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IM698_RS16515	COG3118	belongs to the thioredoxin family
IM698_RS16525	COG0318	PFAM AMP-dependent synthetase and ligase
IM698_RS16555	COG0534	Mate efflux family protein
IM698_RS16580	COG1321	iron dependent repressor
IM698_RS16580	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IM698_RS16585	COG1121	(ABC) transporter
IM698_RS16590	COG0803	Belongs to the bacterial solute-binding protein 9 family
IM698_RS16635	COG0848	biopolymer transport protein
IM698_RS16640	COG0811	peptide transport
IM698_RS16645	COG0811	peptide transport
IM698_RS16655	COG4774	siderophore transport
IM698_RS16660	COG1301	dicarboxylic acid transport
IM698_RS16665	COG2205	protein histidine kinase activity
IM698_RS16670	COG0745	RESPONSE REGULATOR receiver
IM698_RS16685	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IM698_RS16685	COG1648	precorrin-2 dehydrogenase activity
IM698_RS16690	COG2116	formate transmembrane transporter activity
IM698_RS16700	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IM698_RS16760	COG2425	protein containing a von Willebrand factor type A (vWA) domain
IM698_RS16770	COG0494	nUDIX hydrolase
IM698_RS16775	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
IM698_RS16825	COG3706	GGDEF domain
IM698_RS16855	COG1929	Belongs to the glycerate kinase type-1 family
IM698_RS16860	COG0383	alpha-mannosidase activity
IM698_RS16865	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IM698_RS16865	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IM698_RS16865	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IM698_RS16870	COG2188	Transcriptional regulator
IM698_RS16895	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IM698_RS16900	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IM698_RS16905	COG2067	long-chain fatty acid transport protein
IM698_RS16910	COG2267	carboxylic ester hydrolase activity
IM698_RS16925	COG3069	C4-dicarboxylate transmembrane transporter activity
IM698_RS16930	COG2197	response regulator
IM698_RS16935	COG3850	Histidine kinase
IM698_RS16950	COG0243	molybdopterin cofactor binding
IM698_RS16980	COG0183	Belongs to the thiolase family
IM698_RS17025	COG0745	RESPONSE REGULATOR receiver
IM698_RS17055	COG0513	Belongs to the DEAD box helicase family
IM698_RS17060	COG0523	cobalamin synthesis protein
IM698_RS17065	COG0038	chloride channel
IM698_RS17075	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
IM698_RS17085	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
IM698_RS17090	COG1175	transmembrane transport
IM698_RS17100	COG1609	Transcriptional regulator
IM698_RS17105	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IM698_RS17105	COG1017	nitric oxide dioxygenase activity
IM698_RS17110	COG3604	Transcriptional regulator
IM698_RS17130	COG0545	Peptidyl-prolyl cis-trans isomerase
IM698_RS17135	COG1309	transcriptional regulator
IM698_RS17140	COG2130	NADP-dependent
IM698_RS17150	COG0564	pseudouridine synthase activity
IM698_RS17160	COG1686	Belongs to the peptidase S11 family
IM698_RS17175	COG3706	GGDEF domain
IM698_RS17185	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IM698_RS17195	COG3059	membrane
IM698_RS17235	COG2207	Transcriptional regulator
IM698_RS17240	COG1979	alcohol dehydrogenase
IM698_RS17245	COG1126	abc transporter atp-binding protein
IM698_RS17250	COG0765	amino acid transport
IM698_RS17260	COG0765	amino acid transport
IM698_RS17275	COG4977	sequence-specific DNA binding
IM698_RS17285	COG1280	lysine exporter protein (LysE YggA)
IM698_RS17315	COG2824	Alkylphosphonate utilization operon protein PhnA
IM698_RS17345	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IM698_RS17350	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IM698_RS17375	COG1132	(ABC) transporter
IM698_RS17390	COG0446	pyridine nucleotide-disulphide oxidoreductase
IM698_RS17390	COG1902	pentaerythritol trinitrate reductase activity
IM698_RS17400	COG3710	Transcriptional regulator
IM698_RS17415	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IM698_RS17420	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IM698_RS17430	COG2985	domain, Protein
IM698_RS17450	COG1024	Enoyl-CoA hydratase
IM698_RS17480	COG1120	ATPase activity
IM698_RS17490	COG2133	pyrroloquinoline quinone binding
IM698_RS17495	COG1278	Cold shock
IM698_RS17510	COG4681	YaeQ
IM698_RS17520	COG0302	gtp cyclohydrolase
IM698_RS17525	COG0303	'Molybdopterin
IM698_RS17550	COG2897	thiosulfate sulfurtransferase activity
IM698_RS17555	COG3706	GGDEF domain
IM698_RS17555	COG4251	negative regulation of phosphorylation
IM698_RS17555	COG5001	Diguanylate cyclase
IM698_RS17555	COG2203	Gaf domain
IM698_RS17590	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IM698_RS17595	COG0840	transmembrane signaling receptor activity
IM698_RS17600	COG1522	sequence-specific DNA binding
IM698_RS17620	COG2814	Major facilitator Superfamily
IM698_RS17625	COG0583	DNA-binding transcription factor activity
IM698_RS17630	COG2198	Histidine kinase
IM698_RS17630	COG2205	protein histidine kinase activity
IM698_RS17630	COG0784	Response regulator, receiver
IM698_RS17630	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IM698_RS17635	COG3437	response regulator, receiver
IM698_RS17640	COG4604	ABC transporter, ATP-binding protein
IM698_RS17645	COG4605	iron ion homeostasis
IM698_RS17650	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IM698_RS17655	COG4607	ABC-type enterochelin transport system periplasmic component
IM698_RS17685	COG0628	permease
IM698_RS17695	COG1566	PFAM secretion protein HlyD family protein
IM698_RS17705	COG3706	GGDEF domain
IM698_RS17730	COG0402	S-adenosylhomocysteine deaminase activity
IM698_RS17745	COG0583	DNA-binding transcription factor activity
IM698_RS17755	COG0352	thiamine-phosphate diphosphorylase activity
IM698_RS17765	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
IM698_RS17770	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IM698_RS17775	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IM698_RS17780	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IM698_RS17785	COG1116	anion transmembrane transporter activity
IM698_RS17790	COG0351	phosphomethylpyrimidine kinase
IM698_RS17795	COG0697	spore germination
IM698_RS17825	COG3710	Transcriptional regulator
IM698_RS17865	COG1785	Belongs to the alkaline phosphatase family
IM698_RS17875	COG0516	GMP reductase activity
IM698_RS17900	COG0534	Mate efflux family protein
IM698_RS17905	COG0583	DNA-binding transcription factor activity
IM698_RS17910	COG0366	Alpha amylase catalytic
IM698_RS17925	COG0697	spore germination
IM698_RS17945	COG0604	alcohol dehydrogenase
IM698_RS18030	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IM698_RS18035	COG0513	Belongs to the DEAD box helicase family
IM698_RS18040	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
IM698_RS18055	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IM698_RS18090	COG2195	Cleaves the N-terminal amino acid of tripeptides
IM698_RS18100	COG0667	Aldo Keto reductase
IM698_RS18105	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IM698_RS18115	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
IM698_RS18120	COG0513	Belongs to the DEAD box helicase family
IM698_RS18130	COG2176	DNA-directed DNA polymerase activity
IM698_RS18145	COG0513	Belongs to the DEAD box helicase family
IM698_RS18150	COG4989	oxidoreductase activity
IM698_RS18170	COG1538	Outer membrane efflux protein
IM698_RS18175	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IM698_RS18220	COG0668	transmembrane transport
IM698_RS18230	COG4232	protein-disulfide reductase activity
IM698_RS18235	COG3118	belongs to the thioredoxin family
IM698_RS18250	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
IM698_RS18255	COG0697	spore germination
IM698_RS18275	COG2814	Major facilitator Superfamily
IM698_RS18280	COG0583	DNA-binding transcription factor activity
IM698_RS18285	COG5001	Diguanylate cyclase
IM698_RS18290	COG0739	heme binding
IM698_RS18315	COG3314	Sporulation integral membrane protein YlbJ
IM698_RS18325	COG0366	Alpha amylase catalytic
IM698_RS18330	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IM698_RS18335	COG0784	Response regulator, receiver
IM698_RS18335	COG0835	chemotaxis
IM698_RS18340	COG2096	Adenosyltransferase
IM698_RS18345	COG0748	coenzyme F420 binding
IM698_RS18350	COG3721	Heme iron utilization protein
IM698_RS18360	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
IM698_RS18365	COG0811	peptide transport
IM698_RS18370	COG0848	biopolymer transport protein
IM698_RS18380	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IM698_RS18385	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
IM698_RS18430	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
IM698_RS18435	COG3217	Mosc domain protein beta barrel domain protein
IM698_RS18435	COG0633	Ferredoxin
IM698_RS18445	COG0418	dihydroorotase activity
IM698_RS18450	COG2354	Protein conserved in bacteria
IM698_RS18460	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IM698_RS18475	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
IM698_RS18475	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
IM698_RS18480	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
IM698_RS18485	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IM698_RS18490	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IM698_RS18520	COG0730	response to heat
IM698_RS18525	COG0280	phosphate acetyltransferase
IM698_RS18530	COG1414	Transcriptional regulator
IM698_RS18535	COG1012	belongs to the aldehyde dehydrogenase family
IM698_RS18580	COG0583	DNA-binding transcription factor activity
IM698_RS18605	COG1028	Short-chain dehydrogenase reductase Sdr
IM698_RS18620	COG3706	GGDEF domain
IM698_RS18640	COG0583	DNA-binding transcription factor activity
IM698_RS18660	COG1136	(ABC) transporter
IM698_RS18665	COG0577	efflux transmembrane transporter activity
IM698_RS18685	COG3119	arylsulfatase activity
IM698_RS18695	COG0641	radical SAM
IM698_RS18730	COG3833	ABC-type maltose transport systems, permease component
IM698_RS18735	COG1175	transmembrane transport
IM698_RS18745	COG3842	ATPase activity
IM698_RS18760	COG0840	transmembrane signaling receptor activity
IM698_RS18765	COG0714	Associated with various cellular activities
IM698_RS18780	COG2304	oxidoreductase activity
IM698_RS18785	COG2304	oxidoreductase activity
IM698_RS18800	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IM698_RS18805	COG0581	inorganic phosphate transmembrane transporter activity
IM698_RS18810	COG0573	inorganic phosphate transmembrane transporter activity
IM698_RS18820	COG0840	transmembrane signaling receptor activity
IM698_RS18830	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
IM698_RS18835	COG3240	lipase activity
IM698_RS18840	COG0513	Belongs to the DEAD box helicase family
IM698_RS18850	COG1388	LysM domain
IM698_RS18850	COG1376	ErfK ybiS ycfS ynhG family protein
IM698_RS18855	COG0813	purine-nucleoside phosphorylase activity
IM698_RS18885	COG1566	PFAM secretion protein HlyD family protein
IM698_RS18890	COG4720	Psort location CytoplasmicMembrane, score
IM698_RS18895	COG1122	ATPase activity
IM698_RS18910	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
IM698_RS18915	COG1640	4-alpha-glucanotransferase
IM698_RS18920	COG0058	SHG alpha-glucan phosphorylase activity
IM698_RS18925	COG2909	trisaccharide binding
IM698_RS18940	COG1999	signal sequence binding
IM698_RS18955	COG1162	GTPase activity
IM698_RS18960	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
IM698_RS18970	COG4566	intracellular signal transduction
IM698_RS19000	COG3258	Cytochrome c
IM698_RS19040	COG4580	involved in the transport of maltose and maltodextrins
IM698_RS19060	COG0204	Acyl-transferase
IM698_RS19065	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IM698_RS19070	COG3615	Tellurite resistance protein tehB
IM698_RS19075	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IM698_RS19080	COG4667	esterase of the alpha-beta hydrolase superfamily
IM698_RS19085	COG0753	catalase activity
IM698_RS19090	COG1929	Belongs to the glycerate kinase type-1 family
IM698_RS19100	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
IM698_RS19105	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
IM698_RS19110	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IM698_RS19120	COG0561	phosphatase activity
IM698_RS19135	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
IM698_RS19140	COG1414	Transcriptional regulator
IM698_RS19145	COG3623	hexulose-6-phosphate isomerase
IM698_RS19165	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
IM698_RS19170	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IM698_RS19180	COG3623	hexulose-6-phosphate isomerase
IM698_RS19185	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
IM698_RS19190	COG0561	phosphatase activity
IM698_RS19255	COG0583	DNA-binding transcription factor activity
IM698_RS19260	COG3214	Protein conserved in bacteria
IM698_RS19270	COG0561	phosphatase activity
IM698_RS19300	COG0798	PFAM Bile acid sodium symporter
IM698_RS19305	COG0583	DNA-binding transcription factor activity
IM698_RS19315	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
IM698_RS19320	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IM698_RS19325	COG1349	DNA-binding transcription factor activity
IM698_RS19330	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
IM698_RS19335	COG1028	Short-chain dehydrogenase reductase Sdr
IM698_RS19340	COG0583	DNA-binding transcription factor activity
IM698_RS19355	COG1794	racemase activity, acting on amino acids and derivatives
IM698_RS19375	COG2957	Belongs to the agmatine deiminase family
IM698_RS19380	COG0531	amino acid
IM698_RS19385	COG0549	Belongs to the carbamate kinase family
IM698_RS19405	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IM698_RS19415	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IM698_RS19430	COG0583	DNA-binding transcription factor activity
IM698_RS19435	COG2814	Major facilitator Superfamily
IM698_RS19445	COG2197	response regulator
IM698_RS19475	COG0583	DNA-binding transcription factor activity
IM698_RS19480	COG0110	maltose O-acetyltransferase activity
IM698_RS19485	COG1609	Transcriptional regulator
IM698_RS19490	COG2723	6-phospho-beta-galactosidase activity
IM698_RS19505	COG0346	lactoylglutathione lyase activity
IM698_RS19520	COG2015	COG2015, Alkyl sulfatase and related hydrolases
IM698_RS19525	COG0583	DNA-binding transcription factor activity
IM698_RS19530	COG0534	Mate efflux family protein
IM698_RS19535	COG1024	Enoyl-CoA hydratase
IM698_RS19540	COG0300	oxidoreductase activity
IM698_RS19550	COG2723	6-phospho-beta-galactosidase activity
IM698_RS19555	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IM698_RS19555	COG1263	PTS System
IM698_RS19560	COG3265	gluconokinase activity
IM698_RS19565	COG0129	dihydroxy-acid dehydratase activity
IM698_RS19570	COG1609	Transcriptional regulator
IM698_RS19620	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
IM698_RS19620	COG0646	methionine synthase
IM698_RS19645	COG3321	synthase
IM698_RS19645	COG0604	alcohol dehydrogenase
IM698_RS19645	COG1028	Short-chain dehydrogenase reductase Sdr
IM698_RS19655	COG2814	Major facilitator Superfamily
IM698_RS19660	COG2207	Transcriptional regulator
IM698_RS19675	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IM698_RS19700	COG2207	Transcriptional regulator
IM698_RS19715	COG2188	Transcriptional regulator
IM698_RS19725	COG1263	PTS System
IM698_RS19725	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IM698_RS19730	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IM698_RS19735	COG0800	Aldolase
IM698_RS19740	COG2169	Transcriptional regulator
IM698_RS19745	COG1486	melibiose metabolic process
IM698_RS19750	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
IM698_RS19770	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
IM698_RS19775	COG1072	(Pantothenic acid kinase))
IM698_RS19785	COG1063	alcohol dehydrogenase
IM698_RS19790	COG2213	PTS system mannitol-specific
IM698_RS19795	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IM698_RS19810	COG1846	Transcriptional regulator
IM698_RS19835	COG1012	belongs to the aldehyde dehydrogenase family
IM698_RS19840	COG1309	transcriptional regulator
IM698_RS19850	COG0745	RESPONSE REGULATOR receiver
IM698_RS19855	COG2205	protein histidine kinase activity
IM698_RS19875	COG0579	oxidoreductase
IM698_RS19890	COG2204	response regulator
IM698_RS19905	COG0800	Aldolase
IM698_RS19910	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IM698_RS19915	COG4145	pantothenate transmembrane transporter activity
IM698_RS19925	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
IM698_RS19950	COG2194	sulfuric ester hydrolase activity
IM698_RS19975	COG1132	(ABC) transporter
IM698_RS20015	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IM698_RS20040	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IM698_RS20050	COG0259	pyridoxamine-phosphate oxidase activity
IM698_RS20090	COG1444	tRNA N-acetyltransferase activity
IM698_RS20115	COG4608	Belongs to the ABC transporter superfamily
IM698_RS20120	COG0444	Belongs to the ABC transporter superfamily
IM698_RS20130	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IM698_RS20130	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
IM698_RS20145	COG4221	oxidoreductase activity
IM698_RS20160	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IM698_RS20175	COG0765	amino acid transport
IM698_RS20210	COG3842	ATPase activity
IM698_RS20220	COG0745	RESPONSE REGULATOR receiver
IM698_RS20225	COG2205	protein histidine kinase activity
IM698_RS20245	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
IM698_RS20255	COG0625	glutathione transferase activity
IM698_RS20275	COG3321	synthase
IM698_RS20275	COG4221	oxidoreductase activity
IM698_RS20275	COG0604	alcohol dehydrogenase
IM698_RS20275	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IM698_RS20280	COG0583	DNA-binding transcription factor activity
IM698_RS20285	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IM698_RS20290	COG3186	Phenylalanine-4-hydroxylase
IM698_RS20315	COG0217	transcriptional regulatory protein
IM698_RS20330	COG2084	Dehydrogenase
IM698_RS20345	COG0583	DNA-binding transcription factor activity
IM698_RS20360	COG1136	(ABC) transporter
IM698_RS20365	COG4591	ABC-type transport system involved in lipoprotein release permease component
IM698_RS20380	COG3275	phosphorelay sensor kinase activity
IM698_RS20385	COG3279	Response regulator of the LytR AlgR family
IM698_RS20390	COG0612	Peptidase, M16
IM698_RS20400	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IM698_RS20405	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IM698_RS20425	COG1902	pentaerythritol trinitrate reductase activity
IM698_RS20430	COG2814	Major facilitator Superfamily
IM698_RS20435	COG1028	Short-chain dehydrogenase reductase Sdr
IM698_RS20450	COG2205	protein histidine kinase activity
IM698_RS20455	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IM698_RS20455	COG1263	PTS System
IM698_RS20470	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
IM698_RS20480	COG0724	RNA recognition motif
IM698_RS20505	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IM698_RS20520	COG4221	oxidoreductase activity
IM698_RS20530	COG0415	Belongs to the DNA photolyase family
IM698_RS20540	COG3806	Anti-sigma factor
IM698_RS20545	COG1595	DNA-templated transcription, initiation
IM698_RS20555	COG1942	4-Oxalocrotonate Tautomerase
IM698_RS20570	COG0786	glutamate:sodium symporter activity
IM698_RS20595	COG2213	PTS system mannitol-specific
IM698_RS20595	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
IM698_RS20600	COG0246	Mannitol dehydrogenase
IM698_RS20605	COG3722	fumarate hydratase activity
IM698_RS20610	COG0363	glucosamine-6-phosphate deaminase activity
IM698_RS20630	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
IM698_RS20645	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IM698_RS20655	COG3366	ferrous iron transmembrane transporter activity
IM698_RS20660	COG0700	Nucleoside recognition
IM698_RS20665	COG3788	relative of glutathione S-transferase, MAPEG superfamily
IM698_RS20710	COG0596	Alpha beta hydrolase
IM698_RS20725	COG3123	guanosine phosphorylase activity
IM698_RS20730	COG1741	Belongs to the pirin family
IM698_RS20760	COG2197	response regulator
IM698_RS20765	COG3851	Histidine kinase
IM698_RS20770	COG2271	Major facilitator Superfamily
IM698_RS20790	COG1054	Belongs to the UPF0176 family
IM698_RS20805	COG2015	COG2015, Alkyl sulfatase and related hydrolases
IM698_RS20810	COG0583	DNA-binding transcription factor activity
IM698_RS20815	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IM698_RS20820	COG2207	Transcriptional regulator
IM698_RS20820	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IM698_RS20825	COG0534	Mate efflux family protein
IM698_RS20835	COG4172	Belongs to the ABC transporter superfamily
IM698_RS20840	COG0747	negative chemotaxis
IM698_RS20860	COG1304	FMN binding
IM698_RS20865	COG1620	l-lactate permease
IM698_RS20870	COG0583	DNA-binding transcription factor activity
IM698_RS20875	COG1505	serine-type exopeptidase activity
IM698_RS20905	COG0395	ABC-type sugar transport system, permease component
IM698_RS20910	COG2723	6-phospho-beta-galactosidase activity
IM698_RS20915	COG3842	ATPase activity
IM698_RS20920	COG3459	Glycosyltransferase 36 associated
IM698_RS20925	COG2017	converts alpha-aldose to the beta-anomer
IM698_RS20935	COG1609	Transcriptional regulator
IM698_RS20940	COG4172	Belongs to the ABC transporter superfamily
IM698_RS20950	COG1067	ATP-dependent peptidase activity
IM698_RS21000	COG1846	Transcriptional regulator
IM698_RS21015	COG0583	DNA-binding transcription factor activity
IM698_RS21020	COG2259	Doxx family
IM698_RS21030	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
IM698_RS21035	COG3960	tartronate-semialdehyde synthase activity
IM698_RS21040	COG3622	Belongs to the hyi family
IM698_RS21045	COG2084	Dehydrogenase
IM698_RS21060	COG2205	protein histidine kinase activity
IM698_RS21060	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IM698_RS21065	COG0745	RESPONSE REGULATOR receiver
IM698_RS21080	COG0402	S-adenosylhomocysteine deaminase activity
IM698_RS21085	COG3287	FIST C domain
IM698_RS21085	COG2200	EAL domain
IM698_RS21085	COG2199	diguanylate cyclase activity
IM698_RS21105	COG2252	PERMEase
IM698_RS21125	COG4266	Belongs to the allantoicase family
IM698_RS21130	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
IM698_RS21140	COG1309	transcriptional regulator
IM698_RS21190	COG1073	alpha beta
IM698_RS21220	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
IM698_RS21270	COG0789	Transcriptional regulator
IM698_RS21275	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IM698_RS21285	COG0402	S-adenosylhomocysteine deaminase activity
IM698_RS21295	COG1529	Aldehyde oxidase and xanthine dehydrogenase
IM698_RS21320	COG1418	mRNA catabolic process
IM698_RS21325	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IM698_RS21330	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
IM698_RS21370	COG0583	DNA-binding transcription factor activity
IM698_RS21375	COG0625	glutathione transferase activity
IM698_RS21380	COG0583	DNA-binding transcription factor activity
IM698_RS21395	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IM698_RS21400	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
IM698_RS21405	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
IM698_RS21430	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IM698_RS21435	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IM698_RS21440	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IM698_RS21445	COG0577	efflux transmembrane transporter activity
IM698_RS21445	COG1136	(ABC) transporter
IM698_RS21450	COG2205	protein histidine kinase activity
IM698_RS21455	COG0745	RESPONSE REGULATOR receiver
IM698_RS21465	COG1882	Formate acetyltransferase
IM698_RS21480	COG0531	amino acid
IM698_RS21495	COG1609	Transcriptional regulator
IM698_RS21500	COG4948	Mandelate Racemase Muconate Lactonizing
IM698_RS21520	COG0698	ribose 5-phosphate isomerase
IM698_RS21540	COG4166	transmembrane transport
IM698_RS21545	COG0583	DNA-binding transcription factor activity
IM698_RS21570	COG0546	phosphoglycolate phosphatase activity
IM698_RS21575	COG3842	ATPase activity
IM698_RS21580	COG0765	amino acid transport
IM698_RS21590	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IM698_RS21605	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IM698_RS21605	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IM698_RS21605	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IM698_RS21610	COG2207	Transcriptional regulator
IM698_RS21615	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IM698_RS21625	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IM698_RS21630	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IM698_RS21645	COG0840	transmembrane signaling receptor activity
IM698_RS21650	COG0814	amino acid
IM698_RS21655	COG2814	Major facilitator Superfamily
IM698_RS21670	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IM698_RS21685	COG0840	transmembrane signaling receptor activity
IM698_RS21695	COG0583	DNA-binding transcription factor activity
IM698_RS21720	COG0583	DNA-binding transcription factor activity
IM698_RS21730	COG4948	Mandelate Racemase Muconate Lactonizing
IM698_RS21760	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
IM698_RS21765	COG3639	organic phosphonate transmembrane transporter activity
IM698_RS21770	COG3639	organic phosphonate transmembrane transporter activity
IM698_RS21815	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
IM698_RS21820	COG3047	cAMP biosynthetic process
IM698_RS21830	COG4221	oxidoreductase activity
IM698_RS21835	COG0583	DNA-binding transcription factor activity
IM698_RS21840	COG1733	regulation of RNA biosynthetic process
IM698_RS21845	COG1028	Short-chain dehydrogenase reductase Sdr
IM698_RS21860	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IM698_RS21890	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IM698_RS21895	COG1595	DNA-templated transcription, initiation
IM698_RS21920	COG1901	pseudouridine methyltransferase
IM698_RS21975	COG0446	pyridine nucleotide-disulphide oxidoreductase
IM698_RS21990	COG2964	Protein conserved in bacteria
IM698_RS22005	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
IM698_RS22010	COG3639	organic phosphonate transmembrane transporter activity
IM698_RS22015	COG2188	Transcriptional regulator
IM698_RS22020	COG3624	Phosphonate C-P lyase system protein PhnG
IM698_RS22025	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
IM698_RS22030	COG3626	phosphonate metabolism
IM698_RS22035	COG3627	carbon phosphorus lyase activity
IM698_RS22040	COG4107	phosphonate C-P lyase system protein PhnK
IM698_RS22045	COG4778	phosphonate C-P lyase system protein PhnL
IM698_RS22050	COG3454	Phosphonate metabolism
IM698_RS22060	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
IM698_RS22065	COG0110	maltose O-acetyltransferase activity
IM698_RS22070	COG0534	Mate efflux family protein
IM698_RS22100	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
IM698_RS22105	COG2999	glutathione oxidoreductase activity
IM698_RS22115	COG0673	inositol 2-dehydrogenase activity
IM698_RS22135	COG0584	glycerophosphoryl diester phosphodiesterase
IM698_RS22140	COG3842	ATPase activity
IM698_RS22145	COG0395	ABC-type sugar transport system, permease component
IM698_RS22150	COG1175	transmembrane transport
IM698_RS22170	COG4067	protein conserved in archaea
IM698_RS22170	COG0189	ligase activity
IM698_RS22175	COG0189	ligase activity
IM698_RS22225	COG2814	Major facilitator Superfamily
IM698_RS22235	COG0564	pseudouridine synthase activity
IM698_RS22255	COG3385	transposase activity
IM698_RS22265	COG1131	(ABC) transporter
IM698_RS22270	COG2186	Transcriptional regulator
IM698_RS22275	COG5001	Diguanylate cyclase
IM698_RS22285	COG5001	Diguanylate cyclase
IM698_RS22295	COG0745	RESPONSE REGULATOR receiver
IM698_RS22300	COG2205	protein histidine kinase activity
IM698_RS22305	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IM698_RS22310	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
IM698_RS22315	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IM698_RS22320	COG3037	sugar-specific permease SgaT UlaA
IM698_RS22335	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IM698_RS22360	COG0745	RESPONSE REGULATOR receiver
IM698_RS22365	COG0642	Histidine kinase
IM698_RS22370	COG4106	trans-aconitate 2-methyltransferase activity
IM698_RS22390	COG0513	Belongs to the DEAD box helicase family
IM698_RS22405	COG3706	GGDEF domain
IM698_RS22410	COG1278	Cold shock
IM698_RS22415	COG0402	S-adenosylhomocysteine deaminase activity
IM698_RS22420	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
IM698_RS22440	COG0583	DNA-binding transcription factor activity
IM698_RS22455	COG1566	PFAM secretion protein HlyD family protein
IM698_RS22470	COG0733	neurotransmitter:sodium symporter activity
IM698_RS22475	COG2197	response regulator
IM698_RS22480	COG3119	arylsulfatase activity
IM698_RS22485	COG0641	radical SAM
IM698_RS22500	COG0714	Associated with various cellular activities
IM698_RS22530	COG4413	Urea transporter
IM698_RS22545	COG0531	amino acid
IM698_RS22560	COG1280	lysine exporter protein (LysE YggA)
IM698_RS22575	COG1151	hydroxylamine reductase activity
IM698_RS22580	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IM698_RS22605	COG2926	Belongs to the UPF0265 family
IM698_RS22615	COG3132	Protein of unknown function, DUF480
IM698_RS22620	COG2827	Endonuclease containing a URI domain
IM698_RS22650	COG0443	Heat shock 70 kDa protein
IM698_RS22660	COG0179	Fumarylacetoacetate (FAA) hydrolase
IM698_RS22665	COG1280	lysine exporter protein (LysE YggA)
IM698_RS22670	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IM698_RS22680	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IM698_RS22690	COG1845	cytochrome c oxidase, subunit III
IM698_RS22710	COG1612	heme a metabolic process
IM698_RS22715	COG0109	protoheme IX farnesyltransferase activity
IM698_RS22730	COG3530	Putative quorum-sensing-regulated virulence factor
IM698_RS22735	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IM698_RS22750	COG0668	transmembrane transport
IM698_RS22755	COG0569	domain protein
IM698_RS22760	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IM698_RS22765	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IM698_RS22765	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IM698_RS22770	COG1765	OsmC-like protein
IM698_RS22775	COG2885	chlorophyll binding
IM698_RS22785	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IM698_RS22795	COG1840	ABC-type Fe3 transport system, periplasmic component
IM698_RS22800	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IM698_RS22805	COG3842	ATPase activity
IM698_RS22825	COG2375	cellular response to nickel ion
IM698_RS22830	COG3104	oligopeptide transport
IM698_RS22835	COG1760	l-serine dehydratase
IM698_RS22855	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IM698_RS22860	COG1132	(ABC) transporter
IM698_RS22865	COG1132	(ABC) transporter
IM698_RS22890	COG0739	heme binding
IM698_RS22895	COG0393	Putative heavy-metal-binding
IM698_RS22910	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
IM698_RS22915	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
IM698_RS22935	COG0346	lactoylglutathione lyase activity
IM698_RS22950	COG2200	EAL domain
IM698_RS22960	COG2202	Pas domain
IM698_RS22960	COG2200	EAL domain
IM698_RS22960	COG2199	diguanylate cyclase activity
IM698_RS22970	COG0156	8-amino-7-oxononanoate synthase activity
IM698_RS22975	COG1063	alcohol dehydrogenase
IM698_RS23000	COG2249	NAD(P)H dehydrogenase (quinone) activity
IM698_RS23020	COG1454	alcohol dehydrogenase
IM698_RS23025	COG1011	Hydrolase
IM698_RS23055	COG1328	CTP reductase activity
IM698_RS23060	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IM698_RS23065	COG0583	DNA-binding transcription factor activity
IM698_RS23085	COG1289	transmembrane transporter activity
IM698_RS23090	COG0210	DNA helicase
IM698_RS23100	COG1803	Methylglyoxal synthase
IM698_RS23105	COG1879	ABC-type sugar transport system periplasmic component
IM698_RS23110	COG2198	Histidine kinase
IM698_RS23110	COG5002	protein histidine kinase activity
IM698_RS23110	COG0784	Response regulator, receiver
IM698_RS23135	COG3385	transposase activity
IM698_RS23165	COG0625	glutathione transferase activity
IM698_RS23170	COG3064	Membrane
IM698_RS23185	COG2205	protein histidine kinase activity
IM698_RS23190	COG0745	RESPONSE REGULATOR receiver
IM698_RS23225	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IM698_RS23225	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
IM698_RS23225	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IM698_RS23230	COG1105	Belongs to the carbohydrate kinase PfkB family
IM698_RS23235	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
IM698_RS23235	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IM698_RS23240	COG1609	Transcriptional regulator
IM698_RS23245	COG0515	serine threonine protein kinase
IM698_RS23245	COG2815	serine threonine protein kinase
IM698_RS23250	COG2223	nitrite transmembrane transporter activity
IM698_RS23260	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IM698_RS23265	COG0243	molybdopterin cofactor binding
IM698_RS23290	COG1609	Transcriptional regulator
IM698_RS23295	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IM698_RS23300	COG1879	ABC-type sugar transport system periplasmic component
IM698_RS23305	COG1172	Belongs to the binding-protein-dependent transport system permease family
IM698_RS23310	COG1129	ABC transporter
IM698_RS23315	COG1869	D-ribose catabolic process
IM698_RS23335	COG4166	transmembrane transport
IM698_RS23340	COG4174	ABC transporter (Permease)
IM698_RS23345	COG4239	(ABC) transporter, permease
IM698_RS23350	COG4172	Belongs to the ABC transporter superfamily
IM698_RS23360	COG0583	DNA-binding transcription factor activity
IM698_RS23370	COG0355	proton-transporting ATP synthase activity, rotational mechanism
IM698_RS23380	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IM698_RS23390	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IM698_RS23405	COG0356	it plays a direct role in the translocation of protons across the membrane
IM698_RS23415	COG0583	DNA-binding transcription factor activity
IM698_RS23425	COG1012	belongs to the aldehyde dehydrogenase family
IM698_RS23435	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IM698_RS23475	COG3278	Belongs to the heme-copper respiratory oxidase family
IM698_RS23495	COG3300	MHYT domain
IM698_RS23495	COG5001	Diguanylate cyclase
IM698_RS23505	COG0384	phenazine biosynthesis protein PhzF
IM698_RS23530	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
IM698_RS23545	COG2197	response regulator
IM698_RS23550	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IM698_RS23565	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
IM698_RS23575	COG2205	protein histidine kinase activity
IM698_RS23575	COG0784	Response regulator, receiver
IM698_RS23585	COG3119	arylsulfatase activity
IM698_RS23590	COG3119	arylsulfatase activity
IM698_RS23600	COG0714	Associated with various cellular activities
IM698_RS23630	COG0583	DNA-binding transcription factor activity
IM698_RS23635	COG1597	lipid kinase activity
IM698_RS23650	COG0641	radical SAM
IM698_RS23660	COG0405	Gamma-glutamyltransferase
IM698_RS23665	COG0840	transmembrane signaling receptor activity
IM698_RS23690	COG0784	Response regulator, receiver
IM698_RS23690	COG2205	protein histidine kinase activity
IM698_RS23690	COG5002	protein histidine kinase activity
IM698_RS23705	COG1132	(ABC) transporter
IM698_RS23710	COG1538	Outer membrane efflux protein
IM698_RS23715	COG2205	protein histidine kinase activity
IM698_RS23715	COG0784	Response regulator, receiver
IM698_RS23720	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family