locus-tag	class	description
Vt282_RS00005	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
Vt282_RS00025	COG0594	ribonuclease P activity
Vt282_RS00035	COG1126	abc transporter atp-binding protein
Vt282_RS00055	COG0592	DNA-directed DNA polymerase activity
Vt282_RS00065	COG0187	DNA topoisomerase II activity
Vt282_RS00070	COG0071	Belongs to the small heat shock protein (HSP20) family
Vt282_RS00075	COG3977	Valine--pyruvate aminotransferase
Vt282_RS00080	COG0751	glycine-tRNA ligase activity
Vt282_RS00085	COG0752	glycyl-tRNA synthetase alpha subunit
Vt282_RS00090	COG2119	membrane
Vt282_RS00115	COG0604	alcohol dehydrogenase
Vt282_RS00125	COG0129	dihydroxy-acid dehydratase activity
Vt282_RS00130	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Vt282_RS00135	COG3978	acetolactate synthase activity
Vt282_RS00145	COG0606	chelatase, subunit chli
Vt282_RS00155	COG0204	Acyl-transferase
Vt282_RS00160	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
Vt282_RS00165	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
Vt282_RS00175	COG3084	Protein conserved in bacteria
Vt282_RS00180	COG4326	sporulation control protein
Vt282_RS00185	COG1272	protein, Hemolysin III
Vt282_RS00190	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
Vt282_RS00195	COG0569	domain protein
Vt282_RS00200	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Vt282_RS00200	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
Vt282_RS00210	COG0242	peptide deformylase activity
Vt282_RS00215	COG1652	LysM domain
Vt282_RS00220	COG0758	DNA mediated transformation
Vt282_RS00230	COG0551	DNA topoisomerase type I activity
Vt282_RS00235	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
Vt282_RS00240	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
Vt282_RS00245	COG0009	L-threonylcarbamoyladenylate synthase
Vt282_RS00265	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
Vt282_RS00320	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
Vt282_RS00325	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
Vt282_RS00335	COG3852	Histidine kinase
Vt282_RS00345	COG0174	glutamine synthetase
Vt282_RS00355	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
Vt282_RS00370	COG1490	D-aminoacyl-tRNA deacylase activity
Vt282_RS00390	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
Vt282_RS00395	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
Vt282_RS00400	COG3031	protein transport across the cell outer membrane
Vt282_RS00410	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Vt282_RS00415	COG1459	type II secretion system
Vt282_RS00420	COG2165	general secretion pathway protein
Vt282_RS00425	COG2165	general secretion pathway protein
Vt282_RS00430	COG2165	general secretion pathway protein
Vt282_RS00435	COG4795	General secretion pathway protein
Vt282_RS00440	COG3156	type II secretion system protein K
Vt282_RS00445	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
Vt282_RS00450	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
Vt282_RS00465	COG0745	RESPONSE REGULATOR receiver
Vt282_RS00470	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Vt282_RS00475	COG2183	response to ionizing radiation
Vt282_RS00485	COG0596	Alpha beta hydrolase
Vt282_RS00490	COG1040	competence protein
Vt282_RS00500	COG0494	nUDIX hydrolase
Vt282_RS00505	COG1218	3'(2'),5'-bisphosphate nucleotidase
Vt282_RS00520	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Vt282_RS00525	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
Vt282_RS00530	COG1758	RNA polymerase activity
Vt282_RS00535	COG0194	GDP metabolic process
Vt282_RS00540	COG2252	PERMEase
Vt282_RS00550	COG1561	YicC-like family, N-terminal region
Vt282_RS00555	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
Vt282_RS00560	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
Vt282_RS00565	COG1560	Kdo2-lipid A biosynthetic process
Vt282_RS00570	COG1309	transcriptional regulator
Vt282_RS00575	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
Vt282_RS00590	COG0267	Belongs to the bacterial ribosomal protein bL33 family
Vt282_RS00595	COG2194	sulfuric ester hydrolase activity
Vt282_RS00620	COG0859	PFAM glycosyl transferase family 9
Vt282_RS00625	COG3642	lipopolysaccharide core region biosynthetic process
Vt282_RS00630	COG1519	Transferase
Vt282_RS00640	COG0463	Glycosyl transferase, family 2
Vt282_RS00755	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Vt282_RS00805	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Vt282_RS00840	COG0459	protein refolding
Vt282_RS00850	COG1494	fructose-1,6-bisphosphatase
Vt282_RS00860	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
Vt282_RS00865	COG0527	aspartate kinase activity
Vt282_RS00865	COG0460	homoserine dehydrogenase
Vt282_RS00870	COG0626	cystathionine gamma-synthase activity
Vt282_RS00875	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
Vt282_RS00880	COG0281	malic enzyme
Vt282_RS00885	COG0254	rRNA binding
Vt282_RS00890	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
Vt282_RS00895	COG1609	Transcriptional regulator
Vt282_RS00905	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
Vt282_RS00910	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
Vt282_RS00920	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
Vt282_RS00930	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
Vt282_RS00935	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
Vt282_RS00940	COG1053	succinate dehydrogenase
Vt282_RS00945	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
Vt282_RS00950	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Vt282_RS00955	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
Vt282_RS00965	COG1045	serine acetyltransferase
Vt282_RS00970	COG1695	Transcriptional regulator
Vt282_RS00975	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
Vt282_RS00985	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
Vt282_RS00990	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
Vt282_RS00995	COG0137	argininosuccinate synthase activity
Vt282_RS01000	COG0165	Argininosuccinate lyase
Vt282_RS01000	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
Vt282_RS01010	COG3634	alkyl hydroperoxide reductase activity
Vt282_RS01020	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
Vt282_RS01020	COG0678	peroxiredoxin activity
Vt282_RS01030	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
Vt282_RS01060	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
Vt282_RS01075	COG0338	D12 class N6 adenine-specific DNA methyltransferase
Vt282_RS01080	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
Vt282_RS01085	COG0546	phosphoglycolate phosphatase activity
Vt282_RS01090	COG0180	Tryptophanyl-tRNA synthetase
Vt282_RS01100	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Vt282_RS01105	COG3138	arginine N-succinyltransferase
Vt282_RS01125	COG3954	Phosphoribulokinase
Vt282_RS01135	COG0429	hydrolase of the alpha beta-hydrolase fold
Vt282_RS01150	COG2249	NAD(P)H dehydrogenase (quinone) activity
Vt282_RS01165	COG1047	Peptidyl-prolyl cis-trans
Vt282_RS01175	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
Vt282_RS01180	COG0402	S-adenosylhomocysteine deaminase activity
Vt282_RS01185	COG0557	exoribonuclease II activity
Vt282_RS01190	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Vt282_RS01195	COG0051	transcription antitermination factor activity, RNA binding
Vt282_RS01200	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
Vt282_RS01220	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
Vt282_RS01225	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
Vt282_RS01255	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
Vt282_RS01275	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
Vt282_RS01290	COG1841	ribosomal large subunit assembly
Vt282_RS01295	COG0200	Binds to the 23S rRNA
Vt282_RS01300	COG0201	protein transport
Vt282_RS01305	COG0257	Belongs to the bacterial ribosomal protein bL36 family
Vt282_RS01310	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Vt282_RS01315	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
Vt282_RS01330	COG0203	ribosomal protein L17
Vt282_RS01340	COG0545	Peptidyl-prolyl cis-trans isomerase
Vt282_RS01345	COG3061	Opacity-associated protein A
Vt282_RS01345	COG3266	domain, Protein
Vt282_RS01350	COG0697	spore germination
Vt282_RS01355	COG2153	protein acetylation
Vt282_RS01370	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Vt282_RS01370	COG1648	precorrin-2 dehydrogenase activity
Vt282_RS01375	COG0175	sulfate reduction
Vt282_RS01385	COG3273	potassium ion transport
Vt282_RS01385	COG0471	metal ion transport
Vt282_RS01390	COG0529	Catalyzes the synthesis of activated sulfate
Vt282_RS01400	COG0735	belongs to the Fur family
Vt282_RS01500	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
Vt282_RS01605	COG2239	Acts as a magnesium transporter
Vt282_RS01610	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
Vt282_RS01615	COG1660	Displays ATPase and GTPase activities
Vt282_RS01620	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
Vt282_RS01625	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
Vt282_RS01635	COG1137	ATPase activity
Vt282_RS01640	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
Vt282_RS01655	COG0517	IMP dehydrogenase activity
Vt282_RS01655	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
Vt282_RS01665	COG1127	ABC transporter
Vt282_RS01670	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
Vt282_RS01675	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
Vt282_RS01680	COG2854	intermembrane phospholipid transfer
Vt282_RS01690	COG5007	Belongs to the BolA IbaG family
Vt282_RS01700	COG0204	Acyl-transferase
Vt282_RS01755	COG0741	lytic transglycosylase activity
Vt282_RS01760	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
Vt282_RS01780	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Vt282_RS01785	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
Vt282_RS01800	COG0762	integral membrane protein
Vt282_RS01805	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
Vt282_RS01810	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
Vt282_RS01825	COG0527	aspartate kinase activity
Vt282_RS01830	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
Vt282_RS01855	COG0629	single-stranded DNA binding
Vt282_RS01885	COG3267	Type II secretory pathway component ExeA
Vt282_RS01885	COG3409	Peptidoglycan-binding domain 1 protein
Vt282_RS01895	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Vt282_RS01900	COG1459	type II secretion system
Vt282_RS01945	COG1077	Cell shape determining protein MreB Mrl
Vt282_RS01950	COG1792	Involved in formation and maintenance of cell shape
Vt282_RS01955	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
Vt282_RS01960	COG0424	maF-like protein
Vt282_RS01965	COG1530	ribonuclease E activity
Vt282_RS01970	COG3164	Protein of unknown function
Vt282_RS01975	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Vt282_RS01980	COG0312	modulator of DNA gyrase
Vt282_RS02015	COG2358	TRAP transporter, solute receptor (TAXI family
Vt282_RS02035	COG0142	geranyltranstransferase activity
Vt282_RS02040	COG0261	This protein binds to 23S rRNA in the presence of protein L20
Vt282_RS02045	COG0211	Belongs to the bacterial ribosomal protein bL27 family
Vt282_RS02050	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Vt282_RS02055	COG2966	Psort location CytoplasmicMembrane, score
Vt282_RS02060	COG3610	response to peptide
Vt282_RS02070	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
Vt282_RS02080	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
Vt282_RS02085	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
Vt282_RS02090	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Vt282_RS02105	COG0251	oxidation-reduction process
Vt282_RS02110	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
Vt282_RS02125	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
Vt282_RS02135	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Vt282_RS02145	COG0564	pseudouridine synthase activity
Vt282_RS02150	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Vt282_RS02155	COG0525	valine-tRNA ligase activity
Vt282_RS02160	COG2927	DNA polymerase III (CHI subunit)
Vt282_RS02170	COG0795	lipopolysaccharide-transporting ATPase activity
Vt282_RS02175	COG0795	lipopolysaccharide-transporting ATPase activity
Vt282_RS02180	COG0157	Belongs to the NadC ModD family
Vt282_RS02190	COG0716	FMN binding
Vt282_RS02195	COG4974	Belongs to the 'phage' integrase family
Vt282_RS02200	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
Vt282_RS02205	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
Vt282_RS02210	COG2186	Transcriptional regulator
Vt282_RS02215	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
Vt282_RS02220	COG0508	dehydrogenase complex catalyzes the overall conversion of
Vt282_RS02225	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Vt282_RS02240	COG0288	reversible hydration of carbon dioxide
Vt282_RS02245	COG0659	secondary active sulfate transmembrane transporter activity
Vt282_RS02250	COG1131	(ABC) transporter
Vt282_RS02255	COG0842	Transport permease protein
Vt282_RS02265	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
Vt282_RS02270	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
Vt282_RS02280	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Vt282_RS02285	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
Vt282_RS02300	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Vt282_RS02305	COG1752	Esterase of the alpha-beta hydrolase superfamily
Vt282_RS02315	COG1929	Belongs to the glycerate kinase type-1 family
Vt282_RS02320	COG3835	regulator
Vt282_RS02335	COG0004	ammonium transporteR
Vt282_RS02340	COG1840	ABC-type Fe3 transport system, periplasmic component
Vt282_RS02345	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
Vt282_RS02350	COG3842	ATPase activity
Vt282_RS02355	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Vt282_RS02370	COG2971	BadF BadG BcrA BcrD
Vt282_RS02380	COG4608	Belongs to the ABC transporter superfamily
Vt282_RS02385	COG0444	Belongs to the ABC transporter superfamily
Vt282_RS02390	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Vt282_RS02400	COG0747	negative chemotaxis
Vt282_RS02405	COG2205	protein histidine kinase activity
Vt282_RS02405	COG0784	Response regulator, receiver
Vt282_RS02410	COG2813	Specifically methylates the guanine in position
Vt282_RS02415	COG0628	permease
Vt282_RS02420	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
Vt282_RS02440	COG0739	heme binding
Vt282_RS02445	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
Vt282_RS02455	COG2027	D-alanyl-D-alanine carboxypeptidase
Vt282_RS02460	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
Vt282_RS02465	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Vt282_RS02470	COG1534	Rna-binding protein
Vt282_RS02480	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Vt282_RS02490	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Vt282_RS02495	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
Vt282_RS02515	COG0195	Participates in both transcription termination and antitermination
Vt282_RS02520	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
Vt282_RS02525	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
Vt282_RS02530	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
Vt282_RS02535	COG1538	Outer membrane efflux protein
Vt282_RS02540	COG0494	nUDIX hydrolase
Vt282_RS02545	COG3151	Protein conserved in bacteria
Vt282_RS02555	COG3150	esterase
Vt282_RS02565	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
Vt282_RS02570	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Vt282_RS02580	COG3105	Protein conserved in bacteria
Vt282_RS02585	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
Vt282_RS02590	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
Vt282_RS02595	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Vt282_RS02605	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
Vt282_RS02610	COG2857	Cytochrome c1
Vt282_RS02615	COG0625	glutathione transferase activity
Vt282_RS02620	COG2969	positive regulation of protein catabolic process
Vt282_RS02625	COG2823	Periplasmic or secreted lipoprotein
Vt282_RS02630	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
Vt282_RS02635	COG0792	nuclease activity
Vt282_RS02640	COG3107	peptidoglycan biosynthetic process
Vt282_RS02645	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
Vt282_RS02660	COG3116	cell division
Vt282_RS02665	COG0768	penicillin binding
Vt282_RS02675	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
Vt282_RS02690	COG0772	Belongs to the SEDS family
Vt282_RS02705	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
Vt282_RS02710	COG0849	cell division
Vt282_RS02715	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
Vt282_RS02720	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
Vt282_RS02730	COG0653	protein targeting
Vt282_RS02735	COG0494	nUDIX hydrolase
Vt282_RS02745	COG0505	Belongs to the CarA family
Vt282_RS02750	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
Vt282_RS02755	COG0730	response to heat
Vt282_RS02760	COG0583	DNA-binding transcription factor activity
Vt282_RS02765	COG3397	chitin binding
Vt282_RS02775	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
Vt282_RS02780	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
Vt282_RS02795	COG2186	Transcriptional regulator
Vt282_RS02800	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Vt282_RS02805	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
Vt282_RS02815	COG0246	Mannitol dehydrogenase
Vt282_RS02820	COG1904	glucuronate isomerase
Vt282_RS02825	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Vt282_RS02830	COG0800	Aldolase
Vt282_RS02850	COG2731	YhcH YjgK YiaL family protein
Vt282_RS02855	COG0546	phosphoglycolate phosphatase activity
Vt282_RS02865	COG1115	amino acid carrier protein
Vt282_RS02870	COG3022	response to hydroperoxide
Vt282_RS02875	COG0084	hydrolase, TatD family'
Vt282_RS02880	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
Vt282_RS02890	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
Vt282_RS02895	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
Vt282_RS02900	COG0813	purine-nucleoside phosphorylase activity
Vt282_RS02910	COG0560	Phosphoserine phosphatase
Vt282_RS02925	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Vt282_RS02930	COG0583	DNA-binding transcription factor activity
Vt282_RS02935	COG1022	Amp-dependent synthetase and ligase
Vt282_RS02955	COG0534	Mate efflux family protein
Vt282_RS02970	COG0741	lytic transglycosylase activity
Vt282_RS02975	COG2171	N-acyltransferase activity
Vt282_RS02990	COG0450	alkyl hydroperoxide reductase
Vt282_RS02995	COG0583	DNA-binding transcription factor activity
Vt282_RS03000	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
Vt282_RS03010	COG0517	IMP dehydrogenase activity
Vt282_RS03015	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
Vt282_RS03020	COG0343	queuine tRNA-ribosyltransferase activity
Vt282_RS03025	COG1862	Preprotein translocase
Vt282_RS03030	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Vt282_RS03035	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Vt282_RS03045	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
Vt282_RS03055	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
Vt282_RS03070	COG0745	RESPONSE REGULATOR receiver
Vt282_RS03075	COG5002	protein histidine kinase activity
Vt282_RS03085	COG0248	Ppx GppA phosphatase
Vt282_RS03100	COG0581	inorganic phosphate transmembrane transporter activity
Vt282_RS03105	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
Vt282_RS03110	COG0704	Plays a role in the regulation of phosphate uptake
Vt282_RS03135	COG3142	Participates in the control of copper homeostasis
Vt282_RS03160	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Vt282_RS03165	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Vt282_RS03170	COG3141	response to X-ray
Vt282_RS03175	COG0583	DNA-binding transcription factor activity
Vt282_RS03185	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
Vt282_RS03190	COG1074	ATP-dependent DNA helicase activity
Vt282_RS03195	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
Vt282_RS03215	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
Vt282_RS03220	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
Vt282_RS03225	COG2166	iron-sulfur cluster assembly
Vt282_RS03230	COG0820	rRNA (adenine-C2-)-methyltransferase activity
Vt282_RS03240	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
Vt282_RS03245	COG0124	histidyl-tRNA synthetase
Vt282_RS03250	COG2976	Protein conserved in bacteria
Vt282_RS03255	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Vt282_RS03260	COG1160	GTP binding
Vt282_RS03280	COG0517	IMP dehydrogenase activity
Vt282_RS03280	COG0516	GMP reductase activity
Vt282_RS03285	COG0519	Catalyzes the synthesis of GMP from XMP
Vt282_RS03285	COG0518	GMP synthase (glutamine-hydrolyzing) activity
Vt282_RS03290	COG1584	GPR1 FUN34 yaaH family protein
Vt282_RS03295	COG1115	amino acid carrier protein
Vt282_RS03300	COG2873	o-acetylhomoserine
Vt282_RS03305	COG2354	Protein conserved in bacteria
Vt282_RS03310	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
Vt282_RS03350	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
Vt282_RS03355	COG1757	Na H antiporter
Vt282_RS03365	COG1979	alcohol dehydrogenase
Vt282_RS03375	COG1349	DNA-binding transcription factor activity
Vt282_RS03455	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
Vt282_RS03460	COG2867	negative regulation of translational initiation
Vt282_RS03465	COG2914	Belongs to the UPF0125 (RnfH) family
Vt282_RS03470	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Vt282_RS03475	COG0497	DNA recombination
Vt282_RS03480	COG0583	DNA-binding transcription factor activity
Vt282_RS03495	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
Vt282_RS03500	COG0443	Heat shock 70 kDa protein
Vt282_RS03505	COG0484	heat shock protein binding
Vt282_RS03535	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
Vt282_RS03540	COG1253	flavin adenine dinucleotide binding
Vt282_RS03550	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
Vt282_RS03580	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
Vt282_RS03585	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
Vt282_RS03590	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
Vt282_RS03595	COG1187	pseudouridine synthase activity
Vt282_RS03600	COG2840	Smr protein MutS2
Vt282_RS03620	COG3104	oligopeptide transport
Vt282_RS03625	COG0367	asparagine synthase
Vt282_RS03630	COG4651	solute:proton antiporter activity
Vt282_RS03630	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
Vt282_RS03640	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
Vt282_RS03645	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Vt282_RS03645	COG1263	PTS System
Vt282_RS03645	COG2190	(PTS) system
Vt282_RS03655	COG0735	belongs to the Fur family
Vt282_RS03680	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
Vt282_RS03685	COG0033	Phosphoglucomutase
Vt282_RS03695	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
Vt282_RS03710	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
Vt282_RS03715	COG1053	succinate dehydrogenase
Vt282_RS03725	COG0567	Dehydrogenase, E1 component
Vt282_RS03730	COG0508	dehydrogenase complex catalyzes the overall conversion of
Vt282_RS03765	COG3098	single-species biofilm formation
Vt282_RS03770	COG0564	pseudouridine synthase activity
Vt282_RS03775	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
Vt282_RS03780	COG0142	geranyltranstransferase activity
Vt282_RS03790	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
Vt282_RS03795	COG1360	Flagellar Motor Protein
Vt282_RS03800	COG0301	tRNA thio-modification
Vt282_RS03800	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Vt282_RS03805	COG0583	DNA-binding transcription factor activity
Vt282_RS03815	COG2363	Small membrane protein
Vt282_RS03830	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Vt282_RS03835	COG1611	Belongs to the LOG family
Vt282_RS03860	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
Vt282_RS03875	COG1876	peptidase activity
Vt282_RS03885	COG1393	Belongs to the ArsC family
Vt282_RS03905	COG2837	iron assimilation
Vt282_RS03915	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Vt282_RS03930	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
Vt282_RS03940	COG1516	flagellar protein fliS
Vt282_RS03950	COG4191	Histidine kinase
Vt282_RS03960	COG1677	Flagellar hook-basal body complex protein FliE
Vt282_RS03970	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Vt282_RS04010	COG3190	flagellar
Vt282_RS04020	COG1987	bacterial-type flagellum assembly
Vt282_RS04025	COG1684	flagellar biosynthetic protein fliR
Vt282_RS04035	COG0556	nucleotide-excision repair
Vt282_RS04040	COG2840	Smr protein MutS2
Vt282_RS04045	COG2890	protein-(glutamine-N5) methyltransferase activity
Vt282_RS04050	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
Vt282_RS04055	COG2860	membrane
Vt282_RS04060	COG3101	peptidyl-lysine hydroxylation
Vt282_RS04085	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Vt282_RS04090	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Vt282_RS04095	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
Vt282_RS04105	COG0101	tRNA pseudouridine synthase activity
Vt282_RS04110	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
Vt282_RS04115	COG0285	dihydrofolate synthase activity
Vt282_RS04125	COG1286	toxin biosynthetic process
Vt282_RS04130	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
Vt282_RS04135	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Vt282_RS04140	COG1121	(ABC) transporter
Vt282_RS04145	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
Vt282_RS04155	COG1918	ferrous iron import across plasma membrane
Vt282_RS04160	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
Vt282_RS04180	COG3102	Protein conserved in bacteria
Vt282_RS04185	COG1025	Belongs to the peptidase M16 family
Vt282_RS04220	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
Vt282_RS04225	COG0643	Histidine kinase
Vt282_RS04225	COG0784	Response regulator, receiver
Vt282_RS04225	COG2198	Histidine kinase
Vt282_RS04230	COG2201	protein-glutamate methylesterase activity
Vt282_RS04235	COG1192	Involved in chromosome partitioning
Vt282_RS04245	COG0835	chemotaxis
Vt282_RS04255	COG4133	protoheme IX ABC transporter activity
Vt282_RS04260	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Vt282_RS04265	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Vt282_RS04280	COG1138	Cytochrome C-type biogenesis protein
Vt282_RS04285	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Vt282_RS04320	COG1595	DNA-templated transcription, initiation
Vt282_RS04325	COG0183	Belongs to the thiolase family
Vt282_RS04330	COG1250	3-hydroxyacyl-CoA dehydrogenase
Vt282_RS04330	COG1024	Enoyl-CoA hydratase
Vt282_RS04335	COG3005	denitrification pathway
Vt282_RS04340	COG0243	molybdopterin cofactor binding
Vt282_RS04345	COG0133	tryptophan synthase activity
Vt282_RS04350	COG0778	Nitroreductase
Vt282_RS04355	COG0583	DNA-binding transcription factor activity
Vt282_RS04365	COG2832	Protein of unknown function (DUF454)
Vt282_RS04370	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
Vt282_RS04380	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
Vt282_RS04385	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
Vt282_RS04390	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
Vt282_RS04395	COG0251	oxidation-reduction process
Vt282_RS04410	COG2261	transglycosylase associated protein
Vt282_RS04415	COG2983	Belongs to the UPF0260 family
Vt282_RS04425	COG1294	oxidase, subunit
Vt282_RS04430	COG1271	oxidase subunit
Vt282_RS04445	COG1088	dTDP-glucose 4,6-dehydratase activity
Vt282_RS04460	COG0668	transmembrane transport
Vt282_RS04480	COG2226	methyltransferase
Vt282_RS04490	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
Vt282_RS04495	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Vt282_RS04505	COG3139	Protein of unknown function (DUF1315)
Vt282_RS04510	COG3012	SEC-C Motif Domain Protein
Vt282_RS04525	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Vt282_RS04530	COG0215	cysteine-tRNA ligase activity
Vt282_RS04535	COG1435	thymidine kinase activity
Vt282_RS04540	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
Vt282_RS04570	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
Vt282_RS04575	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
Vt282_RS04585	COG0596	Alpha beta hydrolase
Vt282_RS04600	COG3070	regulator of competence-specific genes
Vt282_RS04605	COG1609	Transcriptional regulator
Vt282_RS04615	COG0745	RESPONSE REGULATOR receiver
Vt282_RS04620	COG1434	Gram-negative-bacterium-type cell wall biogenesis
Vt282_RS04625	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Vt282_RS04630	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
Vt282_RS04635	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
Vt282_RS04640	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
Vt282_RS04660	COG0189	ligase activity
Vt282_RS04660	COG4067	protein conserved in archaea
Vt282_RS04670	COG4106	trans-aconitate 2-methyltransferase activity
Vt282_RS04675	COG1801	Protein of unknown function DUF72
Vt282_RS04680	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
Vt282_RS04690	COG2199	diguanylate cyclase activity
Vt282_RS04700	COG4232	protein-disulfide reductase activity
Vt282_RS04705	COG1187	pseudouridine synthase activity
Vt282_RS04715	COG1278	Cold shock
Vt282_RS04720	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
Vt282_RS04725	COG0542	response to heat
Vt282_RS04730	COG1434	Gram-negative-bacterium-type cell wall biogenesis
Vt282_RS04735	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Vt282_RS04755	COG2116	formate transmembrane transporter activity
Vt282_RS04760	COG0390	transport system, permease component
Vt282_RS04765	COG4459	periplasmic nitrate reductase
Vt282_RS04770	COG3005	denitrification pathway
Vt282_RS04775	COG0243	molybdopterin cofactor binding
Vt282_RS04785	COG0632	four-way junction helicase activity
Vt282_RS04790	COG2255	four-way junction helicase activity
Vt282_RS04795	COG1271	oxidase subunit
Vt282_RS04800	COG1294	oxidase, subunit
Vt282_RS04805	COG4890	Cyd operon protein YbgT
Vt282_RS04815	COG0824	Thioesterase
Vt282_RS04820	COG0811	peptide transport
Vt282_RS04840	COG2885	chlorophyll binding
Vt282_RS04845	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
Vt282_RS04850	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
Vt282_RS04875	COG2205	protein histidine kinase activity
Vt282_RS04875	COG0784	Response regulator, receiver
Vt282_RS04930	COG0402	S-adenosylhomocysteine deaminase activity
Vt282_RS04935	COG1522	sequence-specific DNA binding
Vt282_RS04940	COG3681	Belongs to the UPF0597 family
Vt282_RS04960	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Vt282_RS04965	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
Vt282_RS04975	COG0589	response to stress
Vt282_RS05005	COG0346	lactoylglutathione lyase activity
Vt282_RS05045	COG1741	Belongs to the pirin family
Vt282_RS05060	COG0437	4 iron, 4 sulfur cluster binding
Vt282_RS05065	COG3302	dmso reductase anchor subunit
Vt282_RS05080	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Vt282_RS05090	COG2205	protein histidine kinase activity
Vt282_RS05090	COG0784	Response regulator, receiver
Vt282_RS05115	COG5002	protein histidine kinase activity
Vt282_RS05115	COG3850	Histidine kinase
Vt282_RS05120	COG0745	RESPONSE REGULATOR receiver
Vt282_RS05125	COG0463	Glycosyl transferase, family 2
Vt282_RS05145	COG1960	acyl-CoA dehydrogenase activity
Vt282_RS05150	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
Vt282_RS05155	COG0708	Exodeoxyribonuclease III
Vt282_RS05165	COG3923	Primosomal replication protein n
Vt282_RS05175	COG1199	ATP-dependent helicase activity
Vt282_RS05200	COG0156	8-amino-7-oxononanoate synthase activity
Vt282_RS05205	COG2226	methyltransferase
Vt282_RS05210	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
Vt282_RS05225	COG1028	Short-chain dehydrogenase reductase Sdr
Vt282_RS05240	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
Vt282_RS05260	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
Vt282_RS05270	COG0482	sulfurtransferase activity
Vt282_RS05280	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Vt282_RS05285	COG2916	Histone family protein nucleoid-structuring protein H-NS
Vt282_RS05290	COG1757	Na H antiporter
Vt282_RS05295	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
Vt282_RS05300	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
Vt282_RS05305	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Vt282_RS05310	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
Vt282_RS05310	COG0131	Imidazoleglycerol-phosphate dehydratase
Vt282_RS05315	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
Vt282_RS05320	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
Vt282_RS05340	COG1227	inorganic diphosphatase activity
Vt282_RS05350	COG4172	Belongs to the ABC transporter superfamily
Vt282_RS05360	COG4171	peptide transport system, permease
Vt282_RS05375	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
Vt282_RS05380	COG1842	Phage shock protein A
Vt282_RS05395	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Vt282_RS05400	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Vt282_RS05410	COG2818	Glycosylase
Vt282_RS05415	COG0626	cystathionine gamma-synthase activity
Vt282_RS05430	COG0564	pseudouridine synthase activity
Vt282_RS05440	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
Vt282_RS05445	COG4136	ATPase activity
Vt282_RS05450	COG4135	transport system, permease component
Vt282_RS05455	COG4134	Bacterial extracellular solute-binding protein
Vt282_RS05465	COG3313	Fe-S protein
Vt282_RS05480	COG2350	Protein conserved in bacteria
Vt282_RS05485	COG1607	acyl-coa hydrolase
Vt282_RS05515	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
Vt282_RS05530	COG0417	DNA replication proofreading
Vt282_RS05540	COG2197	response regulator
Vt282_RS05545	COG0322	excinuclease ABC activity
Vt282_RS05575	COG2133	pyrroloquinoline quinone binding
Vt282_RS05590	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
Vt282_RS05595	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Vt282_RS05595	COG0072	phenylalanine-tRNA ligase activity
Vt282_RS05600	COG1263	PTS System
Vt282_RS05600	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Vt282_RS05610	COG1621	beta-fructofuranosidase activity
Vt282_RS05615	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Vt282_RS05635	COG0534	Mate efflux family protein
Vt282_RS05650	COG0110	maltose O-acetyltransferase activity
Vt282_RS05655	COG3394	polysaccharide catabolic process
Vt282_RS05670	COG0625	glutathione transferase activity
Vt282_RS05690	COG0583	DNA-binding transcription factor activity
Vt282_RS05695	COG2015	COG2015, Alkyl sulfatase and related hydrolases
Vt282_RS05730	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
Vt282_RS05760	COG1902	pentaerythritol trinitrate reductase activity
Vt282_RS05760	COG0446	pyridine nucleotide-disulphide oxidoreductase
Vt282_RS05770	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Vt282_RS05785	COG5413	integral membrane protein
Vt282_RS05790	COG4191	Histidine kinase
Vt282_RS05795	COG2204	response regulator
Vt282_RS05805	COG0659	secondary active sulfate transmembrane transporter activity
Vt282_RS05810	COG0318	PFAM AMP-dependent synthetase and ligase
Vt282_RS05825	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
Vt282_RS05845	COG4964	Belongs to the GSP D family
Vt282_RS05990	COG2942	2-epimerase
Vt282_RS06035	COG0582	viral genome integration into host DNA
Vt282_RS06050	COG0346	lactoylglutathione lyase activity
Vt282_RS06060	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
Vt282_RS06065	COG1280	lysine exporter protein (LysE YggA)
Vt282_RS06070	COG1115	amino acid carrier protein
Vt282_RS06105	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
Vt282_RS06115	COG1032	radical SAM domain protein
Vt282_RS06135	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
Vt282_RS06145	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
Vt282_RS06160	COG0076	glutamate decarboxylase activity
Vt282_RS06170	COG2431	L-lysine efflux transmembrane transporter activity
Vt282_RS06180	COG3070	regulator of competence-specific genes
Vt282_RS06200	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Vt282_RS06205	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Vt282_RS06220	COG2195	Cleaves the N-terminal amino acid of tripeptides
Vt282_RS06230	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
Vt282_RS06240	COG0625	glutathione transferase activity
Vt282_RS06275	COG0247	lactate metabolic process
Vt282_RS06275	COG0277	FAD linked oxidase domain protein
Vt282_RS06285	COG4160	amino acid transport
Vt282_RS06290	COG4215	(ABC) transporter
Vt282_RS06295	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Vt282_RS06310	COG4326	sporulation control protein
Vt282_RS06325	COG0500	methyltransferase
Vt282_RS06335	COG0471	metal ion transport
Vt282_RS06340	COG4191	Histidine kinase
Vt282_RS06340	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Vt282_RS06360	COG1346	cytolysis
Vt282_RS06365	COG1380	Effector of murein hydrolase LrgA
Vt282_RS06370	COG2925	Exonuclease
Vt282_RS06385	COG1278	Cold shock
Vt282_RS06400	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
Vt282_RS06410	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
Vt282_RS06435	COG4139	cobalamin transport
Vt282_RS06460	COG0583	DNA-binding transcription factor activity
Vt282_RS06465	COG1914	H( )-stimulated, divalent metal cation uptake system
Vt282_RS06480	COG1451	nucleotide metabolic process
Vt282_RS06490	COG3063	Type IV pilus biogenesis stability protein PilW
Vt282_RS06495	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
Vt282_RS06515	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Vt282_RS06525	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
Vt282_RS06540	COG0840	transmembrane signaling receptor activity
Vt282_RS06545	COG0602	queuosine metabolic process
Vt282_RS06550	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
Vt282_RS06565	COG2885	chlorophyll binding
Vt282_RS06585	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
Vt282_RS06590	COG0840	transmembrane signaling receptor activity
Vt282_RS06595	COG1254	Belongs to the acylphosphatase family
Vt282_RS06600	COG2920	part of a sulfur-relay system
Vt282_RS06605	COG0670	Belongs to the BI1 family
Vt282_RS06610	COG1126	abc transporter atp-binding protein
Vt282_RS06615	COG0765	amino acid transport
Vt282_RS06620	COG4597	amino acid ABC transporter
Vt282_RS06625	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Vt282_RS06630	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Vt282_RS06630	COG1648	precorrin-2 dehydrogenase activity
Vt282_RS06635	COG1666	GTP binding
Vt282_RS06640	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
Vt282_RS06670	COG2995	paraquat-inducible protein a
Vt282_RS06680	COG1956	GAF domain-containing protein
Vt282_RS06685	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
Vt282_RS06700	COG0308	aminopeptidase N
Vt282_RS06725	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
Vt282_RS06725	COG0116	Belongs to the methyltransferase superfamily
Vt282_RS06750	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Vt282_RS06820	COG3278	Belongs to the heme-copper respiratory oxidase family
Vt282_RS06835	COG2010	Cytochrome c
Vt282_RS06845	COG2217	Heavy metal translocating P-type atpase
Vt282_RS06865	COG0589	response to stress
Vt282_RS06890	COG3842	ATPase activity
Vt282_RS06900	COG1177	transmembrane transport
Vt282_RS06905	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
Vt282_RS06915	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
Vt282_RS06930	COG0437	4 iron, 4 sulfur cluster binding
Vt282_RS06965	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
Vt282_RS06975	COG0488	(ABC) transporter
Vt282_RS07010	COG4662	Binding-protein-dependent transport system inner membrane component
Vt282_RS07020	COG0746	molybdenum cofactor guanylyltransferase activity
Vt282_RS07025	COG0303	'Molybdopterin
Vt282_RS07035	COG1940	carbohydrate kinase activity
Vt282_RS07050	COG1028	Short-chain dehydrogenase reductase Sdr
Vt282_RS07060	COG0791	NLP P60 protein
Vt282_RS07080	COG0307	riboflavin synthase, alpha
Vt282_RS07085	COG0534	Mate efflux family protein
Vt282_RS07125	COG3976	FMN-binding domain protein
Vt282_RS07125	COG1053	succinate dehydrogenase
Vt282_RS07140	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
Vt282_RS07150	COG1737	Transcriptional regulator
Vt282_RS07155	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Vt282_RS07160	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Vt282_RS07165	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
Vt282_RS07170	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Vt282_RS07180	COG1940	carbohydrate kinase activity
Vt282_RS07185	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
Vt282_RS07245	COG0110	maltose O-acetyltransferase activity
Vt282_RS07260	COG0297	glycogen (starch) synthase activity
Vt282_RS07270	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Vt282_RS07275	COG4178	(ABC) transporter
Vt282_RS07280	COG4178	(ABC) transporter
Vt282_RS07285	COG0612	Peptidase, M16
Vt282_RS07335	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
Vt282_RS07340	COG1366	Belongs to the anti-sigma-factor antagonist family
Vt282_RS07345	COG2208	phosphoserine phosphatase activity
Vt282_RS07360	COG0666	response to abiotic stimulus
Vt282_RS07370	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Vt282_RS07400	COG1126	abc transporter atp-binding protein
Vt282_RS07405	COG0765	amino acid transport
Vt282_RS07410	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Vt282_RS07415	COG0765	amino acid transport
Vt282_RS07425	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
Vt282_RS07430	COG0848	biopolymer transport protein
Vt282_RS07435	COG0811	peptide transport
Vt282_RS07440	COG0811	peptide transport
Vt282_RS07450	COG4774	siderophore transport
Vt282_RS07455	COG2205	protein histidine kinase activity
Vt282_RS07460	COG0745	RESPONSE REGULATOR receiver
Vt282_RS07475	COG0584	glycerophosphoryl diester phosphodiesterase
Vt282_RS07485	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
Vt282_RS07500	COG0583	DNA-binding transcription factor activity
Vt282_RS07525	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
Vt282_RS07530	COG1328	CTP reductase activity
Vt282_RS07555	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Vt282_RS07560	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Vt282_RS07605	COG0019	diaminopimelate decarboxylase activity
Vt282_RS07615	COG0076	glutamate decarboxylase activity
Vt282_RS07625	COG2885	chlorophyll binding
Vt282_RS07645	COG1136	(ABC) transporter
Vt282_RS07650	COG0534	Mate efflux family protein
Vt282_RS07655	COG0702	epimerase
Vt282_RS07660	COG0667	Aldo Keto reductase
Vt282_RS07680	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
Vt282_RS07685	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Vt282_RS07695	COG0678	peroxiredoxin activity
Vt282_RS07695	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
Vt282_RS07710	COG0583	DNA-binding transcription factor activity
Vt282_RS07715	COG2814	Major facilitator Superfamily
Vt282_RS07735	COG1061	Type III restriction enzyme res subunit
Vt282_RS07750	COG2205	protein histidine kinase activity
Vt282_RS07755	COG3706	GGDEF domain
Vt282_RS07760	COG2814	Major facilitator Superfamily
Vt282_RS07800	COG3300	MHYT domain
Vt282_RS07800	COG5001	Diguanylate cyclase
Vt282_RS07805	COG0415	Belongs to the DNA photolyase family
Vt282_RS07810	COG0783	Belongs to the Dps family
Vt282_RS07835	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
Vt282_RS07850	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Vt282_RS07855	COG3108	Peptidase M15
Vt282_RS07885	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Vt282_RS07900	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Vt282_RS07910	COG3768	UPF0283 membrane protein
Vt282_RS07915	COG3106	COG3106 Predicted ATPase
Vt282_RS07945	COG0494	nUDIX hydrolase
Vt282_RS07950	COG0814	amino acid
Vt282_RS07955	COG1760	l-serine dehydratase
Vt282_RS07965	COG0720	synthase
Vt282_RS07975	COG0017	Asparaginyl-tRNA synthetase
Vt282_RS07985	COG1448	Aminotransferase
Vt282_RS07995	COG1643	Atp-dependent helicase
Vt282_RS08000	COG0281	malic enzyme
Vt282_RS08010	COG2949	membrane
Vt282_RS08035	COG0492	ferredoxin-NADP+ reductase activity
Vt282_RS08045	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
Vt282_RS08050	COG0006	proline dipeptidase activity
Vt282_RS08055	COG1522	sequence-specific DNA binding
Vt282_RS08060	COG1012	belongs to the aldehyde dehydrogenase family
Vt282_RS08065	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
Vt282_RS08070	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Vt282_RS08080	COG0513	Belongs to the DEAD box helicase family
Vt282_RS08090	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Vt282_RS08095	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
Vt282_RS08100	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
Vt282_RS08110	COG3706	GGDEF domain
Vt282_RS08120	COG3437	response regulator, receiver
Vt282_RS08130	COG1187	pseudouridine synthase activity
Vt282_RS08135	COG0009	L-threonylcarbamoyladenylate synthase
Vt282_RS08140	COG0613	PHP domain protein
Vt282_RS08150	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
Vt282_RS08155	COG0512	Glutamine amidotransferase of anthranilate synthase
Vt282_RS08160	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Vt282_RS08170	COG0133	tryptophan synthase activity
Vt282_RS08175	COG0159	tryptophan synthase activity
Vt282_RS08180	COG1301	dicarboxylic acid transport
Vt282_RS08195	COG4589	Belongs to the CDS family
Vt282_RS08210	COG1643	Atp-dependent helicase
Vt282_RS08235	COG0840	transmembrane signaling receptor activity
Vt282_RS08255	COG0443	Heat shock 70 kDa protein
Vt282_RS08270	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
Vt282_RS08290	COG1136	(ABC) transporter
Vt282_RS08310	COG3275	phosphorelay sensor kinase activity
Vt282_RS08330	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Vt282_RS08345	COG1882	Formate acetyltransferase
Vt282_RS08355	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
Vt282_RS08360	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
Vt282_RS08375	COG2766	serine protein kinase
Vt282_RS08380	COG2718	Belongs to the UPF0229 family
Vt282_RS08385	COG2719	SpoVR family
Vt282_RS08390	COG2197	response regulator
Vt282_RS08400	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
Vt282_RS08410	COG0243	molybdopterin cofactor binding
Vt282_RS08420	COG3005	denitrification pathway
Vt282_RS08430	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
Vt282_RS08445	COG1132	(ABC) transporter
Vt282_RS08450	COG0658	competence protein
Vt282_RS08450	COG2333	competence protein COMEC
Vt282_RS08460	COG4591	ABC-type transport system involved in lipoprotein release permease component
Vt282_RS08465	COG1136	(ABC) transporter
Vt282_RS08470	COG4591	ABC-type transport system involved in lipoprotein release permease component
Vt282_RS08480	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
Vt282_RS08495	COG1252	NADH dehydrogenase
Vt282_RS08500	COG3150	esterase
Vt282_RS08525	COG0537	adenosine 5'-monophosphoramidase activity
Vt282_RS08530	COG0840	transmembrane signaling receptor activity
Vt282_RS08540	COG3604	Transcriptional regulator
Vt282_RS08545	COG1151	hydroxylamine reductase activity
Vt282_RS08550	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Vt282_RS08555	COG2186	Transcriptional regulator
Vt282_RS08560	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
Vt282_RS08570	COG1674	ftsk spoiiie
Vt282_RS08575	COG1522	sequence-specific DNA binding
Vt282_RS08580	COG0686	Belongs to the AlaDH PNT family
Vt282_RS08585	COG3092	negative regulation of chromosome organization
Vt282_RS08595	COG0857	belongs to the CobB CobQ family
Vt282_RS08595	COG0280	phosphate acetyltransferase
Vt282_RS08625	COG0435	Glutathione S-transferase
Vt282_RS08635	COG0444	Belongs to the ABC transporter superfamily
Vt282_RS08640	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Vt282_RS08645	COG0601	transmembrane transport
Vt282_RS08655	COG4221	oxidoreductase activity
Vt282_RS08660	COG0583	DNA-binding transcription factor activity
Vt282_RS08665	COG2205	protein histidine kinase activity
Vt282_RS08665	COG0784	Response regulator, receiver
Vt282_RS08675	COG2204	response regulator
Vt282_RS08680	COG3064	Membrane
Vt282_RS08685	COG1418	mRNA catabolic process
Vt282_RS08710	COG3300	MHYT domain
Vt282_RS08710	COG5001	Diguanylate cyclase
Vt282_RS08730	COG1946	Acyl-CoA thioesterase
Vt282_RS08760	COG2855	membrane
Vt282_RS08775	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
Vt282_RS08780	COG2267	carboxylic ester hydrolase activity
Vt282_RS08785	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
Vt282_RS08790	COG1169	isochorismate synthase
Vt282_RS08795	COG0436	Aminotransferase
Vt282_RS08820	COG0232	Belongs to the dGTPase family. Type 2 subfamily
Vt282_RS08825	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
Vt282_RS08840	COG1349	DNA-binding transcription factor activity
Vt282_RS08845	COG1349	DNA-binding transcription factor activity
Vt282_RS08855	COG2222	sugar isomerase
Vt282_RS08860	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Vt282_RS08870	COG3716	PTS system mannose fructose sorbose family IID component
Vt282_RS08875	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
Vt282_RS08895	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
Vt282_RS08905	COG0616	signal peptide processing
Vt282_RS08910	COG1028	Short-chain dehydrogenase reductase Sdr
Vt282_RS08930	COG0835	chemotaxis
Vt282_RS08930	COG0784	Response regulator, receiver
Vt282_RS08935	COG1940	carbohydrate kinase activity
Vt282_RS08940	COG4667	esterase of the alpha-beta hydrolase superfamily
Vt282_RS08955	COG0733	neurotransmitter:sodium symporter activity
Vt282_RS08970	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Vt282_RS08970	COG1263	PTS System
Vt282_RS08975	COG0084	hydrolase, TatD family'
Vt282_RS08980	COG0470	DNA polymerase III
Vt282_RS08985	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
Vt282_RS08990	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
Vt282_RS08995	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Vt282_RS09020	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Vt282_RS09030	COG0333	Belongs to the bacterial ribosomal protein bL32 family
Vt282_RS09035	COG1399	metal-binding, possibly nucleic acid-binding protein
Vt282_RS09040	COG0424	maF-like protein
Vt282_RS09045	COG0564	pseudouridine synthase activity
Vt282_RS09050	COG1530	ribonuclease E activity
Vt282_RS09055	COG0659	secondary active sulfate transmembrane transporter activity
Vt282_RS09070	COG0318	PFAM AMP-dependent synthetase and ligase
Vt282_RS09075	COG0596	Alpha beta hydrolase
Vt282_RS09090	COG1214	PFAM Peptidase M22, glycoprotease
Vt282_RS09095	COG1199	ATP-dependent helicase activity
Vt282_RS09105	COG0788	formyltetrahydrofolate deformylase activity
Vt282_RS09115	COG1902	pentaerythritol trinitrate reductase activity
Vt282_RS09115	COG0446	pyridine nucleotide-disulphide oxidoreductase
Vt282_RS09120	COG0616	signal peptide processing
Vt282_RS09125	COG0252	asparaginase activity
Vt282_RS09130	COG3047	cAMP biosynthetic process
Vt282_RS09145	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
Vt282_RS09150	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
Vt282_RS09155	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
Vt282_RS09160	COG3012	SEC-C Motif Domain Protein
Vt282_RS09160	COG3318	Belongs to the UPF0149 family
Vt282_RS09170	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
Vt282_RS09195	COG0583	DNA-binding transcription factor activity
Vt282_RS09215	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
Vt282_RS09220	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
Vt282_RS09230	COG0539	negative regulation of cytoplasmic translation
Vt282_RS09235	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
Vt282_RS09240	COG1555	photosystem II stabilization
Vt282_RS09245	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Vt282_RS09250	COG0776	regulation of translation
Vt282_RS09260	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
Vt282_RS09270	COG0544	peptidyl-prolyl cis-trans isomerase activity
Vt282_RS09275	COG4771	TonB-dependent receptor
Vt282_RS09280	COG0748	coenzyme F420 binding
Vt282_RS09285	COG3721	Heme iron utilization protein
Vt282_RS09295	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
Vt282_RS09300	COG0811	peptide transport
Vt282_RS09305	COG0848	biopolymer transport protein
Vt282_RS09315	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Vt282_RS09340	COG0625	glutathione transferase activity
Vt282_RS09350	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
Vt282_RS09385	COG2195	Cleaves the N-terminal amino acid of tripeptides
Vt282_RS09415	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
Vt282_RS09425	COG0583	DNA-binding transcription factor activity
Vt282_RS09430	COG2951	lytic endotransglycosylase activity
Vt282_RS09435	COG3100	YcgL domain-containing protein
Vt282_RS09440	COG0850	regulation of cytokinetic process
Vt282_RS09445	COG2894	cell division
Vt282_RS09450	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
Vt282_RS09455	COG1012	belongs to the aldehyde dehydrogenase family
Vt282_RS09455	COG1454	alcohol dehydrogenase
Vt282_RS09460	COG2095	MarC family integral membrane protein
Vt282_RS09465	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Vt282_RS09470	COG2186	Transcriptional regulator
Vt282_RS09475	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
Vt282_RS09480	COG1757	Na H antiporter
Vt282_RS09495	COG3082	Protein of unknown function (DUF1414)
Vt282_RS09500	COG3083	sulfuric ester hydrolase activity
Vt282_RS09520	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Vt282_RS09520	COG1648	precorrin-2 dehydrogenase activity
Vt282_RS09535	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Vt282_RS09540	COG4948	Mandelate Racemase Muconate Lactonizing
Vt282_RS09550	COG2721	sulfolactate sulfo-lyase activity
Vt282_RS09560	COG2186	Transcriptional regulator
Vt282_RS09565	COG5001	Diguanylate cyclase
Vt282_RS09570	COG0123	including yeast histone deacetylase and acetoin utilization protein
Vt282_RS09585	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
Vt282_RS09605	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Vt282_RS09610	COG0355	proton-transporting ATP synthase activity, rotational mechanism
Vt282_RS09620	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
Vt282_RS09630	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Vt282_RS09645	COG0356	it plays a direct role in the translocation of protons across the membrane
Vt282_RS09655	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
Vt282_RS09660	COG2982	Protein involved in outer membrane biogenesis
Vt282_RS09665	COG0572	uridine kinase
Vt282_RS09670	COG0489	protein tyrosine kinase activity
Vt282_RS09675	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Vt282_RS09675	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Vt282_RS09705	COG0617	tRNA 3'-terminal CCA addition
Vt282_RS09705	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
Vt282_RS09705	COG0517	IMP dehydrogenase activity
Vt282_RS09710	COG0314	molybdopterin synthase activity
Vt282_RS09715	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
Vt282_RS09720	COG0315	cyclic pyranopterin monophosphate synthase activity
Vt282_RS09725	COG0521	Mo-molybdopterin cofactor biosynthetic process
Vt282_RS09730	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Vt282_RS09735	COG0391	Required for morphogenesis under gluconeogenic growth conditions
Vt282_RS09740	COG2198	Histidine kinase
Vt282_RS09745	COG2204	response regulator
Vt282_RS09750	COG0556	nucleotide-excision repair
Vt282_RS09760	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
Vt282_RS09765	COG4657	Part of a membrane complex involved in electron transport
Vt282_RS09770	COG2878	Part of a membrane complex involved in electron transport
Vt282_RS09775	COG4656	Part of a membrane complex involved in electron transport
Vt282_RS09785	COG4659	FMN binding
Vt282_RS09790	COG4660	Part of a membrane complex involved in electron transport
Vt282_RS09795	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Vt282_RS09800	COG0346	lactoylglutathione lyase activity
Vt282_RS09820	COG2056	Na+-H+ antiporter family
Vt282_RS09830	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Vt282_RS09835	COG2716	regulation of RNA biosynthetic process
Vt282_RS09840	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Vt282_RS09860	COG4783	chaperone-mediated protein folding
Vt282_RS09865	COG1393	Belongs to the ArsC family
Vt282_RS09890	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
Vt282_RS09900	COG2877	3-deoxy-8-phosphooctulonate synthase activity
Vt282_RS09905	COG2912	Transglutaminase-like superfamily
Vt282_RS09910	COG3094	Invasion gene expression up-regulator, SirB
Vt282_RS09915	COG2890	protein-(glutamine-N5) methyltransferase activity
Vt282_RS09920	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
Vt282_RS09925	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
Vt282_RS09930	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
Vt282_RS09940	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
Vt282_RS09945	COG0193	aminoacyl-tRNA hydrolase activity
Vt282_RS10095	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Vt282_RS10105	COG1705	Flagellar rod assembly protein muramidase FlgJ
Vt282_RS10105	COG3951	Flagellar rod assembly protein muramidase FlgJ
Vt282_RS10115	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
Vt282_RS10125	COG4787	bacterial-type flagellum-dependent cell motility
Vt282_RS10130	COG1749	Flagellar hook protein flgE
Vt282_RS10145	COG1815	bacterial-type flagellum-dependent cell motility
Vt282_RS10150	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
Vt282_RS10155	COG0784	Response regulator, receiver
Vt282_RS10155	COG0835	chemotaxis
Vt282_RS10165	COG2747	anti-sigma28 factor FlgM
Vt282_RS10205	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Vt282_RS10210	COG2217	Heavy metal translocating P-type atpase
Vt282_RS10210	COG2608	mercury ion transmembrane transporter activity
Vt282_RS10230	COG0326	Molecular chaperone. Has ATPase activity
Vt282_RS10235	COG3710	Transcriptional regulator
Vt282_RS10255	COG0622	Phosphoesterase
Vt282_RS10280	COG1090	epimerase
Vt282_RS10285	COG0300	oxidoreductase activity
Vt282_RS10290	COG3118	belongs to the thioredoxin family
Vt282_RS10295	COG0330	HflC and HflK could
Vt282_RS10300	COG1585	Membrane protein implicated in regulation of membrane protease activity
Vt282_RS10320	COG3115	cell septum assembly
Vt282_RS10330	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
Vt282_RS10335	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
Vt282_RS10340	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Vt282_RS10345	COG2190	(PTS) system
Vt282_RS10350	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Vt282_RS10355	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Vt282_RS10360	COG1702	phosphate starvation-inducible protein PhoH
Vt282_RS10365	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
Vt282_RS10370	COG4535	Mg2 and Co2 transporter CorC
Vt282_RS10375	COG0815	Transfers the fatty acyl group on membrane lipoproteins
Vt282_RS10385	COG0495	leucyl-tRNA aminoacylation
Vt282_RS10390	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
Vt282_RS10395	COG1466	dna polymerase III delta subunit
Vt282_RS10400	COG0799	negative regulation of ribosome biogenesis
Vt282_RS10410	COG0768	penicillin binding
Vt282_RS10415	COG0772	Belongs to the SEDS family
Vt282_RS10420	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
Vt282_RS10425	COG1686	Belongs to the peptidase S11 family
Vt282_RS10430	COG2921	Belongs to the UPF0250 family
Vt282_RS10440	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
Vt282_RS10450	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
Vt282_RS10465	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
Vt282_RS10480	COG1464	Belongs to the NlpA lipoprotein family
Vt282_RS10505	COG0121	glutamine amidotransferase
Vt282_RS10510	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
Vt282_RS10515	COG1960	acyl-CoA dehydrogenase activity
Vt282_RS10525	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
Vt282_RS10530	COG0328	RNA-DNA hybrid ribonuclease activity
Vt282_RS10535	COG2226	methyltransferase
Vt282_RS10545	COG1388	LysM domain
Vt282_RS10545	COG0741	lytic transglycosylase activity
Vt282_RS10555	COG3021	interspecies interaction between organisms
Vt282_RS10560	COG0347	Belongs to the P(II) protein family
Vt282_RS10565	COG0037	tRNA processing
Vt282_RS10570	COG0825	malonyl-CoA metabolic process
Vt282_RS10575	COG0587	DNA-directed DNA polymerase activity
Vt282_RS10585	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Vt282_RS10595	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Vt282_RS10600	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Vt282_RS10605	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
Vt282_RS10620	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
Vt282_RS10625	COG0575	Belongs to the CDS family
Vt282_RS10630	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
Vt282_RS10640	COG0528	UMP kinase activity
Vt282_RS10645	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
Vt282_RS10655	COG0024	Methionine aminopeptidase
Vt282_RS10660	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
Vt282_RS10670	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
Vt282_RS10680	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Vt282_RS10700	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Vt282_RS10700	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Vt282_RS10710	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
Vt282_RS10730	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
Vt282_RS10735	COG2252	PERMEase
Vt282_RS10740	COG2195	Cleaves the N-terminal amino acid of tripeptides
Vt282_RS10745	COG4067	protein conserved in archaea
Vt282_RS10745	COG0189	ligase activity
Vt282_RS10750	COG0189	ligase activity
Vt282_RS10760	COG0733	neurotransmitter:sodium symporter activity
Vt282_RS10785	COG2991	Protein conserved in bacteria
Vt282_RS10790	COG1477	protein flavinylation
Vt282_RS10795	COG2871	sodium ion transport
Vt282_RS10815	COG1805	sodium ion transport
Vt282_RS10820	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
Vt282_RS10825	COG0271	Belongs to the BolA IbaG family
Vt282_RS10840	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Vt282_RS10855	COG1595	DNA-templated transcription, initiation
Vt282_RS10870	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
Vt282_RS10875	COG0693	protein deglycase activity
Vt282_RS10880	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Vt282_RS10885	COG0105	UTP biosynthetic process
Vt282_RS10895	COG2975	iron-sulfur cluster assembly
Vt282_RS10900	COG0633	Ferredoxin
Vt282_RS10905	COG0443	Heat shock 70 kDa protein
Vt282_RS10915	COG0316	Belongs to the HesB IscA family
Vt282_RS10920	COG0822	iron-sulfur transferase activity
Vt282_RS10925	COG1104	cysteine desulfurase activity
Vt282_RS10935	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
Vt282_RS10940	COG0483	inositol monophosphate 1-phosphatase activity
Vt282_RS10995	COG0564	pseudouridine synthase activity
Vt282_RS11000	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Vt282_RS11005	COG0741	lytic transglycosylase activity
Vt282_RS11010	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
Vt282_RS11015	COG1605	Chorismate mutase
Vt282_RS11015	COG0077	Prephenate dehydratase
Vt282_RS11025	COG5001	Diguanylate cyclase
Vt282_RS11030	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
Vt282_RS11035	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
Vt282_RS11045	COG0488	(ABC) transporter
Vt282_RS11055	COG0739	heme binding
Vt282_RS11060	COG0287	Prephenate dehydrogenase
Vt282_RS11060	COG1605	Chorismate mutase
Vt282_RS11075	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
Vt282_RS11085	COG0612	Peptidase, M16
Vt282_RS11090	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
Vt282_RS11095	COG1047	Peptidyl-prolyl cis-trans
Vt282_RS11110	COG0196	riboflavin kinase activity
Vt282_RS11115	COG0728	peptidoglycan biosynthetic process
Vt282_RS11120	COG0268	Binds directly to 16S ribosomal RNA
Vt282_RS11125	COG0583	DNA-binding transcription factor activity
Vt282_RS11130	COG1283	sodium-dependent phosphate transmembrane transporter activity
Vt282_RS11135	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
Vt282_RS11145	COG0730	response to heat
Vt282_RS11155	COG0494	nUDIX hydrolase
Vt282_RS11160	COG3066	DNA modification
Vt282_RS11170	COG0667	Aldo Keto reductase
Vt282_RS11185	COG2198	Histidine kinase
Vt282_RS11185	COG5002	protein histidine kinase activity
Vt282_RS11185	COG0784	Response regulator, receiver
Vt282_RS11195	COG1242	4 iron, 4 sulfur cluster binding
Vt282_RS11200	COG0069	glutamate synthase activity
Vt282_RS11200	COG0070	glutamate synthase
Vt282_RS11200	COG0067	glutamate synthase
Vt282_RS11235	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
Vt282_RS11240	COG0513	Belongs to the DEAD box helicase family
Vt282_RS11245	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
Vt282_RS11250	COG0456	acetyltransferase
Vt282_RS11260	COG3153	acetyltransferase
Vt282_RS11265	COG3154	lipid carrier protein
Vt282_RS11275	COG0826	peptidase U32
Vt282_RS11280	COG0826	peptidase U32
Vt282_RS11285	COG0737	Belongs to the 5'-nucleotidase family
Vt282_RS11295	COG0534	Mate efflux family protein
Vt282_RS11310	COG1185	polyribonucleotide nucleotidyltransferase activity
Vt282_RS11315	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
Vt282_RS11320	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
Vt282_RS11330	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Vt282_RS11335	COG2860	membrane
Vt282_RS11340	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
Vt282_RS11345	COG0083	homoserine kinase activity
Vt282_RS11360	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
Vt282_RS11370	COG0745	RESPONSE REGULATOR receiver
Vt282_RS11380	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
Vt282_RS11390	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
Vt282_RS11395	COG3025	triphosphatase activity
Vt282_RS11400	COG1392	Phosphate transport regulator
Vt282_RS11405	COG0306	phosphate transporter
Vt282_RS11410	COG4991	sh3 domain protein
Vt282_RS11420	COG3267	Type II secretory pathway component ExeA
Vt282_RS11420	COG3409	Peptidoglycan-binding domain 1 protein
Vt282_RS11425	COG0617	tRNA 3'-terminal CCA addition
Vt282_RS11430	COG0148	phosphopyruvate hydratase activity
Vt282_RS11435	COG0504	CTP synthase activity
Vt282_RS11440	COG3956	TIGRFAM MazG family protein
Vt282_RS11445	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
Vt282_RS11465	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
Vt282_RS11470	COG1381	Involved in DNA repair and RecF pathway recombination
Vt282_RS11475	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
Vt282_RS11490	COG0481	GTPase activity
Vt282_RS11495	COG3086	response to oxidative stress
Vt282_RS11500	COG3026	antisigma factor binding
Vt282_RS11510	COG1595	DNA-templated transcription, initiation
Vt282_RS11515	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
Vt282_RS11525	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
Vt282_RS11545	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Vt282_RS11550	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Vt282_RS11570	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
Vt282_RS11575	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
Vt282_RS11580	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Vt282_RS11590	COG0028	Belongs to the TPP enzyme family
Vt282_RS11595	COG1022	Amp-dependent synthetase and ligase
Vt282_RS11610	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Vt282_RS11615	COG0473	3-isopropylmalate dehydrogenase activity
Vt282_RS11665	COG2188	Transcriptional regulator
Vt282_RS11675	COG1486	melibiose metabolic process
Vt282_RS11690	COG1301	dicarboxylic acid transport
Vt282_RS11705	COG1447	Phosphotransferase system cellobiose-specific component IIA
Vt282_RS11710	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
Vt282_RS11715	COG1446	asparaginase
Vt282_RS11720	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
Vt282_RS11735	COG1854	S-ribosylhomocysteine lyase activity
Vt282_RS11750	COG0612	Peptidase, M16
Vt282_RS11755	COG1238	metal cluster binding
Vt282_RS11760	COG1063	alcohol dehydrogenase
Vt282_RS11765	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
Vt282_RS11770	COG5016	pyruvate
Vt282_RS11770	COG0511	ligase activity, forming carbon-carbon bonds
Vt282_RS11820	COG0527	aspartate kinase activity
Vt282_RS11825	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
Vt282_RS11830	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
Vt282_RS11835	COG1546	Belongs to the CinA family
Vt282_RS11840	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
Vt282_RS11860	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Vt282_RS11865	COG1459	type II secretion system
Vt282_RS11875	COG0237	dephospho-CoA kinase activity
Vt282_RS11880	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
Vt282_RS11885	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
Vt282_RS11890	COG0335	large ribosomal subunit rRNA binding
Vt282_RS11905	COG0228	four-way junction DNA binding
Vt282_RS11910	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
Vt282_RS11915	COG4137	Cytochrome C assembly protein
Vt282_RS11920	COG4536	flavin adenine dinucleotide binding
Vt282_RS11925	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Vt282_RS11940	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
Vt282_RS11945	COG0585	pseudouridine synthase activity
Vt282_RS11955	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
Vt282_RS11960	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
Vt282_RS11970	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
Vt282_RS11975	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
Vt282_RS11980	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
Vt282_RS11985	COG0596	Alpha beta hydrolase
Vt282_RS11990	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
Vt282_RS11995	COG0828	Belongs to the bacterial ribosomal protein bS21 family
Vt282_RS12000	COG1610	YqeY-like protein
Vt282_RS12005	COG0358	DNA primase activity
Vt282_RS12020	COG3706	GGDEF domain
Vt282_RS12025	COG2252	PERMEase
Vt282_RS12040	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
Vt282_RS12045	COG1349	DNA-binding transcription factor activity
Vt282_RS12050	COG0469	pyruvate kinase activity
Vt282_RS12065	COG0583	DNA-binding transcription factor activity
Vt282_RS12070	COG1279	arginine transmembrane transporter activity
Vt282_RS12075	COG0668	transmembrane transport
Vt282_RS12085	COG0126	phosphoglycerate kinase activity
Vt282_RS12090	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
Vt282_RS12095	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
Vt282_RS12100	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
Vt282_RS12110	COG3091	SprT-like family
Vt282_RS12115	COG2356	endonuclease I
Vt282_RS12120	COG1385	rRNA (uridine-N3-)-methyltransferase activity
Vt282_RS12125	COG0189	ligase activity
Vt282_RS12130	COG1678	Uncharacterized ACR, COG1678
Vt282_RS12135	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
Vt282_RS12140	COG0312	modulator of DNA gyrase
Vt282_RS12145	COG3028	Belongs to the UPF0307 family
Vt282_RS12150	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
Vt282_RS12155	COG1178	ABC-type Fe3 transport system permease component
Vt282_RS12160	COG4143	(ABC) transporter
Vt282_RS12165	COG0163	prenyltransferase activity
Vt282_RS12170	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
Vt282_RS12180	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
Vt282_RS12190	COG2105	PFAM AIG2 family protein
Vt282_RS12195	COG2911	Protein conserved in bacteria
Vt282_RS12200	COG0729	surface antigen
Vt282_RS12205	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Vt282_RS12210	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
Vt282_RS12225	COG1136	(ABC) transporter
Vt282_RS12230	COG0577	efflux transmembrane transporter activity
Vt282_RS12230	COG1136	(ABC) transporter
Vt282_RS12250	COG0432	Pfam Uncharacterised protein family UPF0047
Vt282_RS12255	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
Vt282_RS12280	COG2965	DNA replication, synthesis of RNA primer
Vt282_RS12295	COG2906	2 iron, 2 sulfur cluster binding
Vt282_RS12305	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Vt282_RS12310	COG0049	tRNA binding
Vt282_RS12325	COG2923	Belongs to the DsrF TusC family
Vt282_RS12330	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
Vt282_RS12335	COG2964	Protein conserved in bacteria
Vt282_RS12340	COG0545	Peptidyl-prolyl cis-trans isomerase
Vt282_RS12355	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
Vt282_RS12360	COG0330	HflC and HflK could
Vt282_RS12365	COG0330	HflC and HflK could
Vt282_RS12370	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
Vt282_RS12375	COG1923	regulation of RNA biosynthetic process
Vt282_RS12385	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
Vt282_RS12395	COG0802	atpase or kinase
Vt282_RS12400	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
Vt282_RS12470	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
Vt282_RS12475	COG1162	GTPase activity
Vt282_RS12480	COG0688	phosphatidylethanolamine metabolic process
Vt282_RS12485	COG0490	domain, Protein
Vt282_RS12485	COG0471	metal ion transport
Vt282_RS12495	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
Vt282_RS12500	COG4942	peptidase
Vt282_RS12525	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
Vt282_RS12530	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
Vt282_RS12535	COG0085	RNA polymerase activity
Vt282_RS12545	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
Vt282_RS12550	COG0081	regulation of translation
Vt282_RS12560	COG0250	Participates in transcription elongation, termination and antitermination
Vt282_RS12565	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
Vt282_RS12600	COG1072	(Pantothenic acid kinase))
Vt282_RS12610	COG0149	triose-phosphate isomerase activity
Vt282_RS12615	COG0534	Mate efflux family protein
Vt282_RS12620	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
Vt282_RS12625	COG1575	Belongs to the MenA family. Type 1 subfamily
Vt282_RS12635	COG1509	lysine 2,3-aminomutase activity
Vt282_RS12650	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
Vt282_RS12660	COG0745	RESPONSE REGULATOR receiver
Vt282_RS12665	COG2205	protein histidine kinase activity
Vt282_RS12670	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
Vt282_RS12680	COG1027	Aspartate ammonia-lyase
Vt282_RS12685	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
Vt282_RS12690	COG4232	protein-disulfide reductase activity
Vt282_RS12700	COG2095	MarC family integral membrane protein
Vt282_RS12720	COG2198	Histidine kinase
Vt282_RS12720	COG0784	Response regulator, receiver
Vt282_RS12720	COG2205	protein histidine kinase activity
Vt282_RS12725	COG2814	Major facilitator Superfamily
Vt282_RS12740	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Vt282_RS12745	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
Vt282_RS12750	COG0511	ligase activity, forming carbon-carbon bonds
Vt282_RS12755	COG0439	Biotin carboxylase
Vt282_RS12760	COG2264	protein methyltransferase activity
Vt282_RS12770	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
Vt282_RS12775	COG3706	GGDEF domain
Vt282_RS12780	COG0789	Transcriptional regulator
Vt282_RS12785	COG0138	bifunctional purine biosynthesis protein purh
Vt282_RS12790	COG0151	Belongs to the GarS family
Vt282_RS12805	COG1253	flavin adenine dinucleotide binding
Vt282_RS12815	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Vt282_RS12820	COG1573	uracil-dna glycosylase
Vt282_RS12885	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
Vt282_RS12895	COG4206	TonB-dependent receptor
Vt282_RS12900	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
Vt282_RS12915	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Vt282_RS12920	COG0534	Mate efflux family protein
Vt282_RS12930	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
Vt282_RS12935	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
Vt282_RS12940	COG2937	Belongs to the GPAT DAPAT family
Vt282_RS12950	COG3161	chorismate lyase activity
Vt282_RS12955	COG1580	Controls the rotational direction of flagella during chemotaxis
Vt282_RS12960	COG0705	Rhomboid family
Vt282_RS12965	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Vt282_RS12975	COG2177	Part of the ABC transporter FtsEX involved in
Vt282_RS12980	COG2884	Cell division ATP-binding protein ftsE
Vt282_RS12985	COG0552	protein localization to endoplasmic reticulum
Vt282_RS12990	COG0742	ribosomal rna small subunit methyltransferase
Vt282_RS13000	COG2095	MarC family integral membrane protein
Vt282_RS13040	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
Vt282_RS13045	COG0640	Transcriptional regulator
Vt282_RS13050	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
Vt282_RS13055	COG1280	lysine exporter protein (LysE YggA)
Vt282_RS13060	COG2267	carboxylic ester hydrolase activity
Vt282_RS13065	COG0561	phosphatase activity
Vt282_RS13085	COG1011	Hydrolase
Vt282_RS13090	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
Vt282_RS13100	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
Vt282_RS13105	COG0019	diaminopimelate decarboxylase activity
Vt282_RS13130	COG1587	Uroporphyrinogen-III synthase
Vt282_RS13135	COG2959	enzyme of heme biosynthesis
Vt282_RS13140	COG3071	HemY protein
Vt282_RS13185	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
Vt282_RS13200	COG3118	belongs to the thioredoxin family
Vt282_RS13210	COG0248	Ppx GppA phosphatase
Vt282_RS13215	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
Vt282_RS13225	COG0514	ATP-dependent DNA helicase (RecQ)
Vt282_RS13230	COG2962	Rard protein
Vt282_RS13240	COG1280	lysine exporter protein (LysE YggA)
Vt282_RS13245	COG0210	DNA helicase
Vt282_RS13270	COG0339	signal peptide processing
Vt282_RS13275	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
Vt282_RS13280	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Vt282_RS13290	COG1566	PFAM secretion protein HlyD family protein
Vt282_RS13360	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Vt282_RS13365	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Vt282_RS13370	COG2960	long-chain fatty acid transporting porin activity
Vt282_RS13375	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
Vt282_RS13380	COG0583	DNA-binding transcription factor activity
Vt282_RS13415	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Vt282_RS13415	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Vt282_RS13430	COG0084	hydrolase, TatD family'
Vt282_RS13435	COG0805	protein transport
Vt282_RS13440	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Vt282_RS13450	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
Vt282_RS13460	COG2226	methyltransferase
Vt282_RS13465	COG1322	Protein conserved in bacteria
Vt282_RS13475	COG0800	Aldolase
Vt282_RS13480	COG2610	gluconate transmembrane transporter activity
Vt282_RS13485	COG3265	gluconokinase activity
Vt282_RS13490	COG0129	dihydroxy-acid dehydratase activity
Vt282_RS13495	COG1609	Transcriptional regulator
Vt282_RS13500	COG2081	HI0933 family
Vt282_RS13510	COG1528	Iron-storage protein
Vt282_RS13515	COG0589	response to stress
Vt282_RS13530	COG0742	ribosomal rna small subunit methyltransferase
Vt282_RS13535	COG5002	protein histidine kinase activity
Vt282_RS13535	COG5001	Diguanylate cyclase
Vt282_RS13540	COG1522	sequence-specific DNA binding
Vt282_RS13560	COG0006	proline dipeptidase activity
Vt282_RS13565	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
Vt282_RS13580	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
Vt282_RS13585	COG0352	thiamine-phosphate diphosphorylase activity
Vt282_RS13590	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
Vt282_RS13695	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
Vt282_RS13710	COG0183	Belongs to the thiolase family
Vt282_RS13715	COG0583	DNA-binding transcription factor activity
Vt282_RS13720	COG2814	Major facilitator Superfamily
Vt282_RS13730	COG0355	proton-transporting ATP synthase activity, rotational mechanism
Vt282_RS13735	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
Vt282_RS13740	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
Vt282_RS13745	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
Vt282_RS13750	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Vt282_RS13755	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
Vt282_RS13770	COG3312	ion transport
Vt282_RS13775	COG1475	DNA binding
Vt282_RS13780	COG1192	Involved in chromosome partitioning
Vt282_RS13790	COG0445	tRNA wobble uridine modification
Vt282_RS13800	COG0352	thiamine-phosphate diphosphorylase activity
Vt282_RS13805	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
Vt282_RS13810	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
Vt282_RS13815	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Vt282_RS13820	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Vt282_RS13825	COG1116	anion transmembrane transporter activity
Vt282_RS13830	COG0351	phosphomethylpyrimidine kinase
Vt282_RS13840	COG4608	Belongs to the ABC transporter superfamily
Vt282_RS13845	COG0444	Belongs to the ABC transporter superfamily
Vt282_RS13860	COG0217	transcriptional regulatory protein
Vt282_RS13870	COG1566	PFAM secretion protein HlyD family protein
Vt282_RS13880	COG3383	formate dehydrogenase (NAD+) activity
Vt282_RS13935	COG1012	belongs to the aldehyde dehydrogenase family
Vt282_RS13940	COG0814	amino acid
Vt282_RS13945	COG0753	catalase activity
Vt282_RS13970	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
Vt282_RS13975	COG0372	Belongs to the citrate synthase family
Vt282_RS13985	COG2828	Protein conserved in bacteria
Vt282_RS13995	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Vt282_RS14010	COG0583	DNA-binding transcription factor activity
Vt282_RS14035	COG1349	DNA-binding transcription factor activity
Vt282_RS14050	COG0561	phosphatase activity
Vt282_RS14095	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
Vt282_RS14105	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Vt282_RS14105	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Vt282_RS14105	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
Vt282_RS14110	COG1105	Belongs to the carbohydrate kinase PfkB family
Vt282_RS14115	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
Vt282_RS14115	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
Vt282_RS14120	COG1609	Transcriptional regulator
Vt282_RS14130	COG0583	DNA-binding transcription factor activity
Vt282_RS14150	COG1858	cytochrome C peroxidase
Vt282_RS14165	COG2723	6-phospho-beta-galactosidase activity
Vt282_RS14185	COG2909	trisaccharide binding
Vt282_RS14190	COG0058	SHG alpha-glucan phosphorylase activity
Vt282_RS14195	COG1640	4-alpha-glucanotransferase
Vt282_RS14200	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
Vt282_RS14205	COG3788	relative of glutathione S-transferase, MAPEG superfamily
Vt282_RS14230	COG0596	Alpha beta hydrolase
Vt282_RS14235	COG0471	metal ion transport
Vt282_RS14245	COG0010	Belongs to the arginase family
Vt282_RS14250	COG1166	arginine decarboxylase activity
Vt282_RS14265	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
Vt282_RS14270	COG1882	Formate acetyltransferase
Vt282_RS14280	COG2169	Transcriptional regulator
Vt282_RS14295	COG0513	Belongs to the DEAD box helicase family
Vt282_RS14305	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
Vt282_RS14310	COG3366	ferrous iron transmembrane transporter activity
Vt282_RS14315	COG0700	Nucleoside recognition
Vt282_RS14325	COG3339	Conserved Protein
Vt282_RS14330	COG1301	dicarboxylic acid transport
Vt282_RS14345	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Vt282_RS14365	COG0363	glucosamine-6-phosphate deaminase activity
Vt282_RS14375	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
Vt282_RS14380	COG1162	GTPase activity
Vt282_RS14390	COG1999	signal sequence binding
Vt282_RS14400	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
Vt282_RS14425	COG0259	pyridoxamine-phosphate oxidase activity
Vt282_RS14435	COG1262	PFAM Formylglycine-generating sulfatase enzyme
Vt282_RS14460	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Vt282_RS14470	COG1132	(ABC) transporter
Vt282_RS14490	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Vt282_RS14505	COG1122	ATPase activity
Vt282_RS14510	COG4720	Psort location CytoplasmicMembrane, score
Vt282_RS14515	COG1566	PFAM secretion protein HlyD family protein
Vt282_RS14525	COG3706	GGDEF domain
Vt282_RS14540	COG0813	purine-nucleoside phosphorylase activity
Vt282_RS14545	COG3272	Protein of unknown function (DUF1722)
Vt282_RS14550	COG0789	Transcriptional regulator
Vt282_RS14555	COG0415	Belongs to the DNA photolyase family
Vt282_RS14560	COG1388	LysM domain
Vt282_RS14560	COG1376	ErfK ybiS ycfS ynhG family protein
Vt282_RS14570	COG0842	Transport permease protein
Vt282_RS14575	COG1131	(ABC) transporter
Vt282_RS14585	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Vt282_RS14590	COG2084	Dehydrogenase
Vt282_RS14600	COG0513	Belongs to the DEAD box helicase family
Vt282_RS14605	COG4948	Mandelate Racemase Muconate Lactonizing
Vt282_RS14615	COG3976	FMN-binding domain protein
Vt282_RS14615	COG1053	succinate dehydrogenase
Vt282_RS14620	COG1802	Transcriptional regulator
Vt282_RS14665	COG1869	D-ribose catabolic process
Vt282_RS14670	COG0738	Major facilitator superfamily
Vt282_RS14680	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Vt282_RS14685	COG1609	Transcriptional regulator
Vt282_RS14695	COG0513	Belongs to the DEAD box helicase family
Vt282_RS14700	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
Vt282_RS14730	COG0402	S-adenosylhomocysteine deaminase activity
Vt282_RS14735	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
Vt282_RS14740	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
Vt282_RS14750	COG0633	Ferredoxin
Vt282_RS14750	COG3217	Mosc domain protein beta barrel domain protein
Vt282_RS14750	COG0633	Ferredoxin
Vt282_RS14750	COG3217	Mosc domain protein beta barrel domain protein
Vt282_RS14795	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
Vt282_RS14815	COG0667	Aldo Keto reductase
Vt282_RS14825	COG2188	Transcriptional regulator
Vt282_RS14830	COG1263	PTS System
Vt282_RS14830	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Vt282_RS14835	COG2226	methyltransferase
Vt282_RS14880	COG1914	H( )-stimulated, divalent metal cation uptake system
Vt282_RS14885	COG4667	esterase of the alpha-beta hydrolase superfamily
Vt282_RS14925	COG2204	response regulator
Vt282_RS14935	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
Vt282_RS14935	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
Vt282_RS14940	COG0516	GMP reductase activity
Vt282_RS14960	COG1979	alcohol dehydrogenase
Vt282_RS15125	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
Vt282_RS15130	COG0583	DNA-binding transcription factor activity
Vt282_RS15145	COG1486	melibiose metabolic process
Vt282_RS15150	COG1447	Phosphotransferase system cellobiose-specific component IIA
Vt282_RS15155	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
Vt282_RS15230	COG1979	alcohol dehydrogenase
Vt282_RS15265	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
Vt282_RS15285	COG0179	Fumarylacetoacetate (FAA) hydrolase
Vt282_RS15315	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Vt282_RS15325	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
Vt282_RS15330	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
Vt282_RS15345	COG3346	SURF1 family
Vt282_RS15355	COG1612	heme a metabolic process
Vt282_RS15360	COG0109	protoheme IX farnesyltransferase activity
Vt282_RS15370	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
Vt282_RS15375	COG4989	oxidoreductase activity
Vt282_RS15380	COG5001	Diguanylate cyclase
Vt282_RS15380	COG4251	negative regulation of phosphorylation
Vt282_RS15380	COG3706	GGDEF domain
Vt282_RS15380	COG2203	Gaf domain
Vt282_RS15390	COG1309	transcriptional regulator
Vt282_RS15400	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
Vt282_RS15445	COG0583	DNA-binding transcription factor activity
Vt282_RS15460	COG1757	Na H antiporter
Vt282_RS15480	COG5001	Diguanylate cyclase
Vt282_RS15480	COG1716	ATPase activity
Vt282_RS15485	COG0402	S-adenosylhomocysteine deaminase activity
Vt282_RS15495	COG0243	molybdopterin cofactor binding
Vt282_RS15500	COG0437	4 iron, 4 sulfur cluster binding
Vt282_RS15505	COG3302	dmso reductase anchor subunit
Vt282_RS15510	COG3381	protein complex oligomerization
Vt282_RS15520	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
Vt282_RS15525	COG0298	carbon dioxide binding
Vt282_RS15545	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
Vt282_RS15550	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
Vt282_RS15555	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
Vt282_RS15560	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
Vt282_RS15570	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
Vt282_RS15580	COG0601	transmembrane transport
Vt282_RS15585	COG4171	peptide transport system, permease
Vt282_RS15590	COG0444	Belongs to the ABC transporter superfamily
Vt282_RS15595	COG1124	(ABC) transporter
Vt282_RS15600	COG3118	belongs to the thioredoxin family
Vt282_RS15610	COG1278	Cold shock
Vt282_RS15630	COG2814	Major facilitator Superfamily
Vt282_RS15645	COG0668	transmembrane transport
Vt282_RS15650	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
Vt282_RS15655	COG0405	Gamma-glutamyltransferase
Vt282_RS15665	COG1794	racemase activity, acting on amino acids and derivatives
Vt282_RS15710	COG0673	inositol 2-dehydrogenase activity
Vt282_RS15715	COG1765	OsmC-like protein
Vt282_RS15725	COG3706	GGDEF domain
Vt282_RS15760	COG0714	Associated with various cellular activities
Vt282_RS15815	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Vt282_RS15830	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
Vt282_RS15830	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Vt282_RS15830	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Vt282_RS15835	COG2207	Transcriptional regulator
Vt282_RS15845	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Vt282_RS15860	COG0573	inorganic phosphate transmembrane transporter activity
Vt282_RS15865	COG0581	inorganic phosphate transmembrane transporter activity
Vt282_RS15870	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
Vt282_RS15890	COG0384	phenazine biosynthesis protein PhzF
Vt282_RS15900	COG0156	8-amino-7-oxononanoate synthase activity
Vt282_RS16010	COG0653	protein targeting
Vt282_RS16030	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
Vt282_RS16035	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Vt282_RS16040	COG0583	DNA-binding transcription factor activity
Vt282_RS16045	COG1840	ABC-type Fe3 transport system, periplasmic component
Vt282_RS16080	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Vt282_RS16085	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
Vt282_RS16090	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Vt282_RS16105	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Vt282_RS16105	COG1263	PTS System
Vt282_RS16110	COG0456	acetyltransferase
Vt282_RS16115	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
Vt282_RS16120	COG0662	Cupin 2, conserved barrel domain protein
Vt282_RS16125	COG0527	aspartate kinase activity
Vt282_RS16130	COG1288	antiporter activity
Vt282_RS16140	COG0330	HflC and HflK could
Vt282_RS16215	COG2897	thiosulfate sulfurtransferase activity
Vt282_RS16230	COG0302	gtp cyclohydrolase
Vt282_RS16235	COG0513	Belongs to the DEAD box helicase family
Vt282_RS16240	COG0277	FAD linked oxidase domain protein
Vt282_RS16270	COG2814	Major facilitator Superfamily
Vt282_RS16280	COG1846	Transcriptional regulator
Vt282_RS16285	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
Vt282_RS16295	COG0814	amino acid
Vt282_RS16305	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
Vt282_RS16310	COG0513	Belongs to the DEAD box helicase family
Vt282_RS16340	COG3040	lipid binding
Vt282_RS16350	COG0446	pyridine nucleotide-disulphide oxidoreductase
Vt282_RS16375	COG1328	CTP reductase activity
Vt282_RS16380	COG0602	queuosine metabolic process
Vt282_RS16395	COG0189	ligase activity
Vt282_RS16395	COG4067	protein conserved in archaea
Vt282_RS16410	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
Vt282_RS16410	COG2885	chlorophyll binding
Vt282_RS16440	COG2827	Endonuclease containing a URI domain
Vt282_RS16445	COG1879	ABC-type sugar transport system periplasmic component
Vt282_RS16460	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
Vt282_RS16465	COG1289	transmembrane transporter activity
Vt282_RS16470	COG0210	DNA helicase
Vt282_RS16485	COG2198	Histidine kinase
Vt282_RS16485	COG0784	Response regulator, receiver
Vt282_RS16485	COG2205	protein histidine kinase activity
Vt282_RS16495	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
Vt282_RS16515	COG1492	cobalamin metabolic process
Vt282_RS16520	COG0725	ABC transporter, periplasmic molybdate-binding protein
Vt282_RS16525	COG4149	molybdate abc transporter
Vt282_RS16540	COG4251	negative regulation of phosphorylation
Vt282_RS16540	COG5001	Diguanylate cyclase
Vt282_RS16540	COG2203	Gaf domain
Vt282_RS16540	COG3706	GGDEF domain
Vt282_RS16545	COG3706	GGDEF domain
Vt282_RS16565	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
Vt282_RS16590	COG3140	Belongs to the UPF0181 family
Vt282_RS16605	COG0023	Translation Initiation Factor
Vt282_RS16620	COG1181	Belongs to the D-alanine--D-alanine ligase family
Vt282_RS16630	COG0045	succinate-CoA ligase (ADP-forming) activity
Vt282_RS16630	COG1042	CoA-binding domain protein
Vt282_RS16630	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Vt282_RS16635	COG0583	DNA-binding transcription factor activity
Vt282_RS16645	COG4533	DNA binding
Vt282_RS16655	COG2050	protein possibly involved in aromatic compounds catabolism
Vt282_RS16670	COG2824	Alkylphosphonate utilization operon protein PhnA
Vt282_RS16685	COG0861	Integral membrane protein TerC family
Vt282_RS16690	COG0737	Belongs to the 5'-nucleotidase family
Vt282_RS16700	COG0583	DNA-binding transcription factor activity
Vt282_RS16705	COG2116	formate transmembrane transporter activity
Vt282_RS16710	COG2353	YceI-like domain
Vt282_RS16715	COG3038	cytochrome b561
Vt282_RS16730	COG3069	C4-dicarboxylate transmembrane transporter activity
Vt282_RS16740	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
Vt282_RS16750	COG1984	allophanate hydrolase subunit 2
Vt282_RS16765	COG4181	ATPase activity
Vt282_RS16775	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
Vt282_RS16790	COG0484	heat shock protein binding
Vt282_RS16805	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Vt282_RS16820	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Vt282_RS16865	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Vt282_RS16995	COG0463	Glycosyl transferase, family 2
Vt282_RS17360	COG0701	Predicted permease
Vt282_RS17365	COG2985	domain, Protein
Vt282_RS17385	COG2304	oxidoreductase activity
Vt282_RS17400	COG0714	Associated with various cellular activities
Vt282_RS17405	COG3063	Type IV pilus biogenesis stability protein PilW
Vt282_RS17415	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
Vt282_RS17420	COG2814	Major facilitator Superfamily
Vt282_RS17435	COG2759	Belongs to the formate--tetrahydrofolate ligase family
Vt282_RS17440	COG2264	protein methyltransferase activity
Vt282_RS17445	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Vt282_RS17445	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Vt282_RS17465	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
Vt282_RS17470	COG0363	glucosamine-6-phosphate deaminase activity
Vt282_RS17475	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
Vt282_RS17485	COG2095	MarC family integral membrane protein
Vt282_RS17490	COG3300	MHYT domain
Vt282_RS17490	COG5001	Diguanylate cyclase
Vt282_RS17495	COG3122	Protein conserved in bacteria
Vt282_RS17500	COG0513	Belongs to the DEAD box helicase family
Vt282_RS17535	COG0318	PFAM AMP-dependent synthetase and ligase
Vt282_RS17545	COG0739	heme binding
Vt282_RS17550	COG0523	cobalamin synthesis protein
Vt282_RS17555	COG0583	DNA-binding transcription factor activity
Vt282_RS17565	COG1139	Iron-sulfur cluster binding protein
Vt282_RS17570	COG0247	lactate metabolic process
Vt282_RS17575	COG1620	l-lactate permease
Vt282_RS17580	COG4628	conserved protein (DUF2132)
Vt282_RS17585	COG0488	(ABC) transporter
Vt282_RS17590	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
Vt282_RS17595	COG0789	Transcriptional regulator
Vt282_RS17600	COG4604	ABC transporter, ATP-binding protein
Vt282_RS17605	COG4605	iron ion homeostasis
Vt282_RS17610	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Vt282_RS17625	COG4172	Belongs to the ABC transporter superfamily
Vt282_RS17630	COG4239	(ABC) transporter, permease
Vt282_RS17635	COG4174	ABC transporter (Permease)
Vt282_RS17640	COG4166	transmembrane transport
Vt282_RS17655	COG1067	ATP-dependent peptidase activity
Vt282_RS17675	COG0798	PFAM Bile acid sodium symporter
Vt282_RS17700	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
Vt282_RS17715	COG0840	transmembrane signaling receptor activity
Vt282_RS17725	COG1280	lysine exporter protein (LysE YggA)
Vt282_RS17770	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
Vt282_RS17805	COG0523	cobalamin synthesis protein
Vt282_RS17825	COG0419	ATPase involved in DNA repair
Vt282_RS17830	COG0420	3'-5' exonuclease activity
Vt282_RS17835	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Vt282_RS17865	COG2995	paraquat-inducible protein a
Vt282_RS17885	COG2502	aspartate--ammonia ligase
Vt282_RS17910	COG0697	spore germination
Vt282_RS17915	COG2425	protein containing a von Willebrand factor type A (vWA) domain
Vt282_RS17930	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
Vt282_RS17940	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
Vt282_RS17950	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
Vt282_RS17985	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Vt282_RS17990	COG0835	chemotaxis
Vt282_RS17990	COG0784	Response regulator, receiver
Vt282_RS17995	COG3706	GGDEF domain
Vt282_RS18010	COG1760	l-serine dehydratase
Vt282_RS18015	COG3104	oligopeptide transport
Vt282_RS18035	COG2199	diguanylate cyclase activity
Vt282_RS18035	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
Vt282_RS18040	COG1011	Hydrolase
Vt282_RS18085	COG3119	arylsulfatase activity
Vt282_RS18090	COG0641	radical SAM
Vt282_RS18125	COG3530	Putative quorum-sensing-regulated virulence factor
Vt282_RS18140	COG1686	Belongs to the peptidase S11 family
Vt282_RS18150	COG1278	Cold shock
Vt282_RS18165	COG2205	protein histidine kinase activity
Vt282_RS18170	COG0745	RESPONSE REGULATOR receiver
Vt282_RS18175	COG0471	metal ion transport
Vt282_RS18180	COG1017	nitric oxide dioxygenase activity
Vt282_RS18180	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Vt282_RS18185	COG3604	Transcriptional regulator
Vt282_RS18195	COG0546	phosphoglycolate phosphatase activity
Vt282_RS18200	COG2249	NAD(P)H dehydrogenase (quinone) activity
Vt282_RS18215	COG0697	spore germination
Vt282_RS18235	COG5001	Diguanylate cyclase
Vt282_RS18245	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
Vt282_RS18270	COG0509	glycine decarboxylation via glycine cleavage system
Vt282_RS18310	COG3706	GGDEF domain
Vt282_RS18340	COG2814	Major facilitator Superfamily
Vt282_RS18345	COG0772	Belongs to the SEDS family
Vt282_RS18355	COG0346	lactoylglutathione lyase activity
Vt282_RS18360	COG1902	pentaerythritol trinitrate reductase activity
Vt282_RS18365	COG1881	PFAM PEBP family protein
Vt282_RS18385	COG2233	PERMEase
Vt282_RS18390	COG0402	S-adenosylhomocysteine deaminase activity
Vt282_RS18475	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
Vt282_RS18485	COG0668	transmembrane transport
Vt282_RS18500	COG0384	phenazine biosynthesis protein PhzF
Vt282_RS18510	COG4628	conserved protein (DUF2132)
Vt282_RS18520	COG0291	Belongs to the bacterial ribosomal protein bL35 family
Vt282_RS18530	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
Vt282_RS18535	COG0800	Aldolase
Vt282_RS18545	COG1028	Short-chain dehydrogenase reductase Sdr
Vt282_RS18550	COG1414	Transcriptional regulator
Vt282_RS18570	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
Vt282_RS18575	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
Vt282_RS18575	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Vt282_RS18580	COG3716	PTS system mannose fructose sorbose family IID component
Vt282_RS18585	COG3715	PTS system
Vt282_RS18590	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Vt282_RS18625	COG1595	DNA-templated transcription, initiation
Vt282_RS18650	COG0583	DNA-binding transcription factor activity
Vt282_RS18655	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
Vt282_RS18670	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Vt282_RS18675	COG1349	DNA-binding transcription factor activity
Vt282_RS18685	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Vt282_RS18690	COG0738	Major facilitator superfamily
Vt282_RS18725	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
Vt282_RS18735	COG2207	Transcriptional regulator
Vt282_RS18735	COG1917	Cupin 2, conserved barrel domain protein
Vt282_RS18745	COG2249	NAD(P)H dehydrogenase (quinone) activity
Vt282_RS18750	COG0583	DNA-binding transcription factor activity
Vt282_RS18770	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
Vt282_RS18775	COG1263	PTS System
Vt282_RS18775	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Vt282_RS18790	COG2909	trisaccharide binding
Vt282_RS18795	COG0058	SHG alpha-glucan phosphorylase activity
Vt282_RS18800	COG1640	4-alpha-glucanotransferase
Vt282_RS18805	COG0366	Alpha amylase catalytic
Vt282_RS18810	COG0840	transmembrane signaling receptor activity
Vt282_RS18820	COG3842	ATPase activity
Vt282_RS18830	COG1175	transmembrane transport
Vt282_RS18835	COG3833	ABC-type maltose transport systems, permease component
Vt282_RS18850	COG0589	response to stress
Vt282_RS18875	COG2249	NAD(P)H dehydrogenase (quinone) activity
Vt282_RS18880	COG0583	DNA-binding transcription factor activity
Vt282_RS18885	COG0529	Catalyzes the synthesis of activated sulfate
Vt282_RS18895	COG0789	Transcriptional regulator
Vt282_RS18950	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Vt282_RS18955	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Vt282_RS18970	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Vt282_RS18970	COG0574	Belongs to the PEP-utilizing enzyme family
Vt282_RS19040	COG0583	DNA-binding transcription factor activity
Vt282_RS19070	COG0672	)-iron permease
Vt282_RS19080	COG2837	iron assimilation
Vt282_RS19085	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
Vt282_RS19095	COG2807	transmembrane transport
Vt282_RS19100	COG2207	Transcriptional regulator
Vt282_RS19150	COG0737	Belongs to the 5'-nucleotidase family
Vt282_RS19180	COG1280	lysine exporter protein (LysE YggA)
Vt282_RS19210	COG0786	glutamate:sodium symporter activity
Vt282_RS19255	COG1024	Enoyl-CoA hydratase
Vt282_RS19260	COG0583	DNA-binding transcription factor activity
Vt282_RS19275	COG1301	dicarboxylic acid transport
Vt282_RS19280	COG1252	NADH dehydrogenase
Vt282_RS19300	COG1028	Short-chain dehydrogenase reductase Sdr
Vt282_RS19325	COG1263	PTS System
Vt282_RS19325	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Vt282_RS19330	COG0583	DNA-binding transcription factor activity
Vt282_RS19335	COG0583	DNA-binding transcription factor activity
Vt282_RS19350	COG0531	amino acid
Vt282_RS19370	COG4176	ABC-type proline glycine betaine transport system permease component
Vt282_RS19375	COG3448	diguanylate cyclase activity
Vt282_RS19375	COG4175	Glycine betaine
Vt282_RS19405	COG1253	flavin adenine dinucleotide binding
Vt282_RS19425	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Vt282_RS19430	COG1349	DNA-binding transcription factor activity
Vt282_RS19450	COG0667	Aldo Keto reductase
Vt282_RS19455	COG0738	Major facilitator superfamily
Vt282_RS19505	COG0531	amino acid
Vt282_RS19510	COG0531	amino acid
Vt282_RS19540	COG0383	alpha-mannosidase activity
Vt282_RS19545	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Vt282_RS19545	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Vt282_RS19545	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
Vt282_RS19550	COG2188	Transcriptional regulator
Vt282_RS19575	COG2190	(PTS) system
Vt282_RS19575	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Vt282_RS19575	COG1263	PTS System
Vt282_RS19580	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Vt282_RS19610	COG1882	Formate acetyltransferase
Vt282_RS19625	COG3059	membrane
Vt282_RS19645	COG0745	RESPONSE REGULATOR receiver
Vt282_RS19660	COG0745	RESPONSE REGULATOR receiver
Vt282_RS19685	COG3153	acetyltransferase
Vt282_RS19690	COG3811	Belongs to the UPF0386 family
Vt282_RS19695	COG0583	DNA-binding transcription factor activity
Vt282_RS19740	COG2814	Major facilitator Superfamily
Vt282_RS19745	COG2207	Transcriptional regulator
Vt282_RS19760	COG1501	Belongs to the glycosyl hydrolase 31 family
Vt282_RS19765	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Vt282_RS19775	COG0583	DNA-binding transcription factor activity
Vt282_RS19780	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Vt282_RS19790	COG1342	Belongs to the UPF0251 family
Vt282_RS19805	COG2176	DNA-directed DNA polymerase activity
Vt282_RS19820	COG0583	DNA-binding transcription factor activity
Vt282_RS19845	COG1511	domain protein
Vt282_RS19845	COG3264	Mechanosensitive ion channel
Vt282_RS19850	COG0604	alcohol dehydrogenase
Vt282_RS19865	COG1444	tRNA N-acetyltransferase activity