locus-tag	class	description
GZI12_RS00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
GZI12_RS00010	ENOG4105EAB	amino acid AbC transporter
GZI12_RS00015	ENOG4105E5Q	amino acid AbC transporter
GZI12_RS00020	ENOG4105CDA	abc transporter atp-binding protein
GZI12_RS00040	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GZI12_RS00045	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
GZI12_RS00050	ENOG4105QTB	Flavodoxin
GZI12_RS00055	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
GZI12_RS00060	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
GZI12_RS00065	ENOG4107QJE	Chromosome Partitioning Protein
GZI12_RS00075	ENOG410684E	atp synthase
GZI12_RS00085	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
GZI12_RS00095	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
GZI12_RS00100	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
GZI12_RS00105	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
GZI12_RS00110	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
GZI12_RS00115	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
GZI12_RS00120	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
GZI12_RS00125	ENOG4105CZQ	inner membrane transport protein YdhC
GZI12_RS00130	ENOG4105F52	Transcriptional regulator
GZI12_RS00135	ENOG4105CHU	acetyl-coa acetyltransferase
GZI12_RS00140	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
GZI12_RS00145	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
GZI12_RS00150	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
GZI12_RS00155	ENOG4108RR8	protoporphyrinogen oxidase
GZI12_RS00265	ENOG4105WMR	Protein CrcB homolog
GZI12_RS00270	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
GZI12_RS00275	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
GZI12_RS00280	ENOG4105D06	uba thif-type nad fad binding protein
GZI12_RS00290	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
GZI12_RS00295	ENOG4105D41	biosynthesis protein thiH
GZI12_RS00300	ENOG4105DC7	peptidase M24
GZI12_RS00305	ENOG4105G2Y	Transcriptional regulator
GZI12_RS00320	ENOG4108VVK	transcriptional Regulator, AsnC
GZI12_RS00330	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
GZI12_RS00345	ENOG4108M6U	Universal stress protein A
GZI12_RS00350	ENOG41090A1	ferritin
GZI12_RS00355	ENOG4108V6B	universal stress protein B
GZI12_RS00360	ENOG4105CBX	hi0933 family
GZI12_RS00365	ENOG4105DIQ	Transcriptional regulator
GZI12_RS00370	ENOG4105C01	Dihydroxy-acid dehydratase
GZI12_RS00375	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
GZI12_RS00380	ENOG4105C6Z	Gluconate
GZI12_RS00385	ENOG4108UHU	Aldolase
GZI12_RS00395	ENOG4105CGY	Dna recombination protein
GZI12_RS00405	ENOG4105JC1	sterol-binding domain protein
GZI12_RS00410	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
GZI12_RS00415	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
GZI12_RS00420	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
GZI12_RS00425	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
GZI12_RS00430	ENOG4105F8V	Hydrolase, tatD family
GZI12_RS00435	ENOG4105D52	delta-aminolevulinic acid dehydratase
GZI12_RS00440	ENOG4105KD7	acetyltransferase
GZI12_RS00455	ENOG4106RE7	Cytochrome
GZI12_RS00465	ENOG4105ZR3	A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis (By similarity)
GZI12_RS00470	ENOG4105XCT	Protein of unknown function (DUF2489)
GZI12_RS00475	ENOG4105D4P	Coproporphyrinogen iii oxidase
GZI12_RS00480	ENOG4105EMY	transcriptional regulator
GZI12_RS00490	ENOG4105W0Z	cytoplasmic protein
GZI12_RS00495	ENOG4105BZS	acriflavin resistance protein
GZI12_RS00500	ENOG410624X	efflux transporter, rnd family, mfp subunit
GZI12_RS00505	ENOG4105Y7M	Transcriptional regulator, TetR family
GZI12_RS00510	ENOG4105C4R	Atp-dependent dna helicase
GZI12_RS00515	ENOG4105MPD	Cytochrome
GZI12_RS00550	ENOG4107QSI	ABC, transporter
GZI12_RS00555	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
GZI12_RS00560	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
GZI12_RS00565	ENOG4105DIJ	Phosphoethanolamine transferase
GZI12_RS00575	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
GZI12_RS00580	ENOG4105CW7	secretion protein, HlyD family
GZI12_RS00590	ENOG4105DC8	reductase
GZI12_RS00595	ENOG4105D6S	protein involved in catabolism of external DNA
GZI12_RS00600	ENOG4105DGW	oligopeptidase A
GZI12_RS00625	ENOG4105C4R	Atp-dependent dna helicase
GZI12_RS00630	ENOG4105CCF	Lysine exporter protein (Lyse ygga)
GZI12_RS00640	ENOG4105FR1	rard protein
GZI12_RS00645	ENOG4105C9U	ATP-dependent DNA helicase RecQ
GZI12_RS00655	ENOG4105EX9	Membrane
GZI12_RS00660	ENOG4105C9X	ppx gppa phosphatase
GZI12_RS00665	ENOG4105C1J	atp-dependent rna helicase
GZI12_RS00675	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
GZI12_RS00685	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
GZI12_RS00695	ENOG4107QK7	reductase
GZI12_RS00735	ENOG410601J	HemY protein
GZI12_RS00740	ENOG4105ECF	c-methyltransferase
GZI12_RS00745	ENOG41076E6	Uroporphyrinogen-III Synthase
GZI12_RS00750	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
GZI12_RS00755	ENOG4107T0K	Adenylate cyclase
GZI12_RS00760	ENOG4105XQ6	frataxin-like protein
GZI12_RS00770	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
GZI12_RS00785	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
GZI12_RS00790	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
GZI12_RS00810	ENOG4105DQF	Hydrolase
GZI12_RS00815	ENOG4105E8V	Alpha Beta Hydrolase Fold protein
GZI12_RS00820	ENOG410829K	Lysine exporter protein (Lyse ygga)
GZI12_RS00825	ENOG4105D58	Diguanylate phosphodiesterase
GZI12_RS00830	ENOG41082YX	Transcriptional regulator, arsr family
GZI12_RS00835	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
GZI12_RS00875	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
GZI12_RS00885	ENOG4106H78	methyltransferase
GZI12_RS00890	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
GZI12_RS00895	ENOG4105CAK	Cell division ATP-binding protein ftsE
GZI12_RS00900	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
GZI12_RS00905	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GZI12_RS00910	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
GZI12_RS00915	ENOG4105EBW	Rhomboid-type serine protease that catalyzes intramembrane proteolysis (By similarity)
GZI12_RS00920	ENOG4105X6C	Flagellar basal body-associated protein FliL
GZI12_RS00930	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
GZI12_RS00940	ENOG41080IJ	Diacylglycerol kinase
GZI12_RS00945	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
GZI12_RS00955	ENOG4107R73	Mate efflux family protein
GZI12_RS00990	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
GZI12_RS01050	ENOG4108RG0	uracil-dna glycosylase
GZI12_RS01055	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
GZI12_RS01060	ENOG4105R2J	Conserved Protein
GZI12_RS01080	ENOG4105C12	Phosphoribosylglycinamide synthetase
GZI12_RS01085	ENOG4105DC1	bifunctional purine biosynthesis protein purh
GZI12_RS01090	ENOG4105W1Y	Transcriptional regulator
GZI12_RS01095	ENOG4105BZU	Histidine kinase
GZI12_RS01100	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
GZI12_RS01105	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
GZI12_RS01115	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
GZI12_RS01120	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
GZI12_RS01125	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
GZI12_RS01130	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
GZI12_RS01145	ENOG4105D8G	Major Facilitator superfamily
GZI12_RS01150	ENOG4105BZU	Histidine kinase
GZI12_RS01160	ENOG4107QN1	sodium solute
GZI12_RS01170	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
GZI12_RS01190	ENOG4108IJ0	Aspartate ammonia-lyase
GZI12_RS01200	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
GZI12_RS01205	ENOG4105E0F	Histidine kinase
GZI12_RS01210	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
GZI12_RS01220	ENOG41076HS	cation diffusion facilitator family transporter
GZI12_RS01225	ENOG4105CTQ	phosphohexokinase
GZI12_RS01235	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
GZI12_RS01240	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
GZI12_RS01245	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
GZI12_RS01250	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
GZI12_RS01260	ENOG4105CP7	Triose-phosphate isomerase
GZI12_RS01300	ENOG4105PM1	preprotein translocase subunit SecE
GZI12_RS01305	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
GZI12_RS01310	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
GZI12_RS01315	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
GZI12_RS01320	ENOG4108VZM	50s ribosomal protein L10
GZI12_RS01325	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
GZI12_RS01330	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
GZI12_RS01335	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
GZI12_RS01340	ENOG4108ZVW	Anti-RNA polymerase sigma 70 factor
GZI12_RS01345	ENOG4105E09	nadh pyrophosphatase
GZI12_RS01350	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
GZI12_RS01355	ENOG41062JF	Transcriptional regulator
GZI12_RS01365	ENOG41063SB	peptidase
GZI12_RS01370	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
GZI12_RS01380	ENOG4107QWE	)-transporter
GZI12_RS01385	ENOG4105DJ4	phosphatidylserine decarboxylase
GZI12_RS01390	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
GZI12_RS01395	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
GZI12_RS01475	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
GZI12_RS01480	ENOG4105K8N	protein family UPF0079, ATPase
GZI12_RS01485	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
GZI12_RS01490	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
GZI12_RS01495	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
GZI12_RS01505	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
GZI12_RS01510	ENOG4107QJR	hflk protein
GZI12_RS01515	ENOG4105EPW	hflc protein
GZI12_RS01525	ENOG41069P5	Protein slyX homolog
GZI12_RS01535	ENOG4108V1T	peptidylprolyl cis-trans isomerase
GZI12_RS01540	ENOG4105WWK	YheO domain protein
GZI12_RS01550	ENOG4108ZKU	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
GZI12_RS01560	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
GZI12_RS01565	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
GZI12_RS01570	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
GZI12_RS01575	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
GZI12_RS01580	ENOG4105W53	bacterioferritin-associated ferredoxin
GZI12_RS01585	ENOG4108UQY	Iron-storage protein
GZI12_RS01595	ENOG4108VDV	Binds single-stranded DNA at the primosome assembly site (PAS) (By similarity)
GZI12_RS01600	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
GZI12_RS01605	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
GZI12_RS01615	ENOG4105CDU	Replicative dna helicase
GZI12_RS01620	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
GZI12_RS01625	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
GZI12_RS01630	ENOG4107QP8	phosphohexose isomerase
GZI12_RS01665	ENOG4108UUE	Transcriptional regulator
GZI12_RS01670	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
GZI12_RS01680	ENOG4105MA0	exported protein
GZI12_RS01685	ENOG41066HZ	AIG2-like family
GZI12_RS01700	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
GZI12_RS01705	ENOG4105DFU	Cell wall formation (By similarity)
GZI12_RS01710	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
GZI12_RS01715	ENOG4105DP9	ABC transporter
GZI12_RS01720	ENOG4106SMU	thiamine transporter membrane protein
GZI12_RS01725	ENOG4107T0D	ABC, transporter
GZI12_RS01730	ENOG4105N42	UPF0307 protein
GZI12_RS01735	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
GZI12_RS01740	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
GZI12_RS01750	ENOG4105D7Z	glutathione synthase
GZI12_RS01755	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
GZI12_RS01760	ENOG4105RWS	endonuclease I
GZI12_RS01765	ENOG4105GPY	SprT protein
GZI12_RS01785	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
GZI12_RS01795	ENOG4105D2N	Aldolase
GZI12_RS01800	ENOG4105D64	Mechanosensitive ion channel
GZI12_RS01805	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
GZI12_RS01810	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
GZI12_RS01815	ENOG4105MPN	Membrane
GZI12_RS01825	ENOG4105CA9	Pyruvate kinase
GZI12_RS01830	ENOG410804X	Transcriptional regulator
GZI12_RS01840	ENOG4105E61	Mannitol repressor protein
GZI12_RS01845	ENOG4107SQ3	mannitol-1-phosphate 5-dehydrogenase
GZI12_RS01850	ENOG4105CTS	PTS system mannitol-specific
GZI12_RS01865	ENOG4105C7N	Xanthine uracil vitamin C permease
GZI12_RS01880	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GZI12_RS01885	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
GZI12_RS01890	ENOG4105KTH	gatB Yqey
GZI12_RS01895	ENOG4105VCC	30S ribosomal protein S21
GZI12_RS01900	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
GZI12_RS01905	ENOG4105F2Z	3-oxoadipate enol-lactonase
GZI12_RS01910	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
GZI12_RS01915	ENOG4107ZVW	dihydroneopterin aldolase
GZI12_RS01920	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GZI12_RS01925	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
GZI12_RS01930	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
GZI12_RS01935	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
GZI12_RS01940	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
GZI12_RS01945	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
GZI12_RS01950	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
GZI12_RS01955	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
GZI12_RS01960	ENOG4108K5P	(LipO)protein
GZI12_RS01965	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GZI12_RS01970	ENOG4108JU6	CBS domain protein
GZI12_RS01975	ENOG4106KVJ	cytochrome C assembly protein
GZI12_RS01980	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GZI12_RS01990	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
GZI12_RS01995	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
GZI12_RS02000	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
GZI12_RS02005	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
GZI12_RS02010	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
GZI12_RS02015	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
GZI12_RS02020	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
GZI12_RS02025	ENOG4105D7Q	type ii secretion system
GZI12_RS02030	ENOG4107QHF	type ii secretion system protein e
GZI12_RS02035	ENOG4105KHS	type IV fimbrial pilin protein
GZI12_RS02040	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
GZI12_RS02050	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
GZI12_RS02060	ENOG4105CFH	Aspartokinase
GZI12_RS02065	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
GZI12_RS02120	ENOG4107QSA	Oxaloacetate decarboxylase
GZI12_RS02125	ENOG4105D9Q	decarboxylase (Beta subunit)
GZI12_RS02135	ENOG4105W39	Membrane
GZI12_RS02145	ENOG4105D9M	gamma-glutamylcysteine synthetase
GZI12_RS02155	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
GZI12_RS02170	ENOG4105CK1	PTS System
GZI12_RS02180	ENOG4105VZJ	PTS System
GZI12_RS02185	ENOG4105VCP	PTS System
GZI12_RS02195	ENOG4105C28	cystathionine
GZI12_RS02200	ENOG4105CK2	sodium dicarboxylate symporter
GZI12_RS02215	ENOG4105F8D	glycoside hydrolase family 4
GZI12_RS02220	ENOG4105CI1	PTS System
GZI12_RS02225	ENOG4105FDP	GntR family transcriptional regulator
GZI12_RS02270	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
GZI12_RS02275	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
GZI12_RS02300	ENOG4108IQE	Amp-dependent synthetase and ligase
GZI12_RS02305	ENOG4105C7K	acetolactate synthase
GZI12_RS02310	ENOG4108ZP8	Acetolactate synthase small subunit
GZI12_RS02315	ENOG4108JQ1	Dehydrogenase
GZI12_RS02320	ENOG4105E66	phosphoriboisomerase A
GZI12_RS02325	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
GZI12_RS02345	ENOG4105D0A	hydroxylase
GZI12_RS02350	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
GZI12_RS02370	ENOG4105Y75	tpr repeat protein
GZI12_RS02380	ENOG4108IYU	L-aspartate oxidase
GZI12_RS02385	ENOG4105EMN	RNA polymerase sigma factor
GZI12_RS02395	ENOG4105VQK	sigma E regulatory protein, MucB RseB
GZI12_RS02400	ENOG4105WMJ	Positive regulator of sigma E, RseC MucC
GZI12_RS02405	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
GZI12_RS02410	ENOG4105C3F	Signal peptidase i
GZI12_RS02415	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
GZI12_RS02430	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
GZI12_RS02440	ENOG4105BZU	Histidine kinase
GZI12_RS02445	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
GZI12_RS02450	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
GZI12_RS02455	ENOG4105DXN	mazG family
GZI12_RS02470	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
GZI12_RS02485	ENOG4106MWK	domain protein
GZI12_RS02490	ENOG4105CJ3	phosphate transporter
GZI12_RS02495	ENOG4107IX6	phosphate transport regulator
GZI12_RS02500	ENOG4105I7R	Adenylate cyclase
GZI12_RS02510	ENOG4108NVR	Methyl-accepting chemotaxis
GZI12_RS02515	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
GZI12_RS02525	ENOG41065U4	response regulator
GZI12_RS02535	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
GZI12_RS02555	ENOG4105D98	threonine synthase
GZI12_RS02560	ENOG4105EN6	Membrane
GZI12_RS02565	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
GZI12_RS02570	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
GZI12_RS02600	ENOG4105C3S	Mate efflux family protein
GZI12_RS02610	ENOG4105CGH	5'-nucleotidase
GZI12_RS02625	ENOG4105BZU	Histidine kinase
GZI12_RS02635	ENOG4108YYD	acetyltransferase
GZI12_RS02645	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
GZI12_RS02650	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
GZI12_RS02655	ENOG4105C1J	atp-dependent rna helicase
GZI12_RS02660	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
GZI12_RS02665	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
GZI12_RS02675	ENOG4105CRK	lysyL-tRNA synthetase
GZI12_RS02680	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GZI12_RS02700	ENOG4105N5T	Radical SAM Protein
GZI12_RS02710	ENOG4105BZU	Histidine kinase
GZI12_RS02735	ENOG4105IRT	Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair (By similarity)
GZI12_RS02740	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
GZI12_RS02745	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
GZI12_RS02750	ENOG4105HF0	Membrane
GZI12_RS02755	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
GZI12_RS02760	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
GZI12_RS02770	ENOG41063Z6	transcriptional regulator, lysR family
GZI12_RS02775	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
GZI12_RS02780	ENOG4105CJR	Integral membrane protein (MviN
GZI12_RS02785	ENOG4105DTN	riboflavin biosynthesis protein ribF
GZI12_RS02795	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
GZI12_RS02800	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
GZI12_RS02805	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
GZI12_RS02820	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
GZI12_RS02830	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
GZI12_RS02850	ENOG4105C5H	ABC transporter
GZI12_RS02855	ENOG4107SC1	transglycosylase
GZI12_RS02865	ENOG4108K16	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
GZI12_RS02885	ENOG4108WPH	sigma 54 modulation protein ribosomal protein S30EA
GZI12_RS02900	ENOG4105C34	Pseudouridine synthase
GZI12_RS02905	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
GZI12_RS02910	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
GZI12_RS02955	ENOG4105ECY	inositol monophosphatase
GZI12_RS02960	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
GZI12_RS02965	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
GZI12_RS02970	ENOG4105C3J	Cysteine desulfurase
GZI12_RS02975	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
GZI12_RS02980	ENOG4108Z4V	iron-sulfur cluster assembly
GZI12_RS02985	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
GZI12_RS02990	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
GZI12_RS02995	ENOG4108ZIT	Ferredoxin, 2FE-2S
GZI12_RS03000	ENOG4105WVQ	Fe-S assembly protein IscX
GZI12_RS03005	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
GZI12_RS03015	ENOG4105C9B	Cysteine desulfurase
GZI12_RS03020	ENOG4107S0N	DJ-1 family
GZI12_RS03025	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
GZI12_RS03040	ENOG4105K6V	RNA polymerase
GZI12_RS03055	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
GZI12_RS03065	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
GZI12_RS03070	ENOG4105M85	Bola protein
GZI12_RS03075	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
GZI12_RS03080	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
GZI12_RS03085	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
GZI12_RS03090	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
GZI12_RS03095	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
GZI12_RS03100	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
GZI12_RS03105	ENOG4105CJ2	(LipO)protein
GZI12_RS03120	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
GZI12_RS03135	ENOG4105C8J	)-transporter
GZI12_RS03155	ENOG4105CIN	aminoacyl-histidine dipeptidase
GZI12_RS03160	ENOG4105C7N	Xanthine uracil vitamin C permease
GZI12_RS03165	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
GZI12_RS03170	ENOG4108DJV	Fermentation respiration switch protein
GZI12_RS03180	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
GZI12_RS03190	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
GZI12_RS03195	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
GZI12_RS03210	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
GZI12_RS03220	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
GZI12_RS03225	ENOG4108ZAI	phosphatidylglycerophosphatase a
GZI12_RS03230	ENOG4108T8E	UPF0325 protein
GZI12_RS03235	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
GZI12_RS03240	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
GZI12_RS03245	ENOG4105CE9	30S ribosomal protein S2
GZI12_RS03250	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
GZI12_RS03255	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
GZI12_RS03260	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
GZI12_RS03265	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
GZI12_RS03270	ENOG4105KNE	Phosphatidate cytidylyltransferase
GZI12_RS03275	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
GZI12_RS03280	ENOG4105DZP	Membrane-associated zinc metalloprotease
GZI12_RS03290	ENOG4108RFI	Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity)
GZI12_RS03295	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
GZI12_RS03300	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
GZI12_RS03305	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
GZI12_RS03310	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
GZI12_RS03315	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
GZI12_RS03320	ENOG4105C0B	DNA polymerase III (alpha subunit)
GZI12_RS03325	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
GZI12_RS03335	ENOG4108YZA	Nitrogen regulatory protein pii
GZI12_RS03340	ENOG4107NA1	Endonuclease Exonuclease phosphatase
GZI12_RS03350	ENOG4105E9H	Lytic Murein transglycosylase
GZI12_RS03355	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
GZI12_RS03360	ENOG4105D1A	Methyltransferase
GZI12_RS03370	ENOG4107RZZ	dna polymerase iii epsilon subunit
GZI12_RS03380	ENOG4107QPN	acyl-Coa dehydrogenase
GZI12_RS03385	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
GZI12_RS03390	ENOG4105E7A	Glutamine amidotransferase
GZI12_RS03395	ENOG4108HM4	ABC transporter
GZI12_RS03400	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
GZI12_RS03405	ENOG4108R96	Methyltransferase, YaeB family
GZI12_RS03415	ENOG4105D01	(LipO)protein
GZI12_RS03425	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
GZI12_RS03430	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
GZI12_RS03445	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
GZI12_RS03455	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
GZI12_RS03460	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
GZI12_RS03470	ENOG4105DZ1	carboxypeptidase
GZI12_RS03475	ENOG4105K6T	rare lipoprotein A
GZI12_RS03480	ENOG4105CNI	cell division protein FtsW
GZI12_RS03485	ENOG4105CJN	penicillin-binding protein
GZI12_RS03490	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
GZI12_RS03495	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
GZI12_RS03500	ENOG4105DJF	DNA polymerase III, delta' subunit
GZI12_RS03505	ENOG4108U2H	Rare lipoprotein B
GZI12_RS03510	ENOG4105C8T	Leucyl-tRNA synthetase
GZI12_RS03515	ENOG4107PAI	alpha helical protein
GZI12_RS03520	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
GZI12_RS03525	ENOG4108JU5	Magnesium and cobalt efflux protein
GZI12_RS03530	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
GZI12_RS03535	ENOG4105C9A	Phoh family
GZI12_RS03540	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
GZI12_RS03545	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
GZI12_RS03550	ENOG4105C5Y	PTS System
GZI12_RS03555	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
GZI12_RS03560	ENOG4105KZ7	phosphocarrier protein hpr
GZI12_RS03565	ENOG4105C6T	cysteine synthase
GZI12_RS03575	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
GZI12_RS03580	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
GZI12_RS03595	ENOG4105G5H	Membrane
GZI12_RS03600	ENOG4107QX8	SPFH domain, Band 7 family protein
GZI12_RS03605	ENOG4107QR8	Thioredoxin
GZI12_RS03610	ENOG4105E1F	short-chain dehydrogenase reductase
GZI12_RS03615	ENOG4105ECP	epimerase
GZI12_RS03640	ENOG4108RE9	Phosphodiesterase
GZI12_RS03660	ENOG4108DQ1	activator toxR
GZI12_RS03665	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
GZI12_RS03670	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
GZI12_RS03675	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
GZI12_RS03685	ENOG4105C59	p-type ATPase
GZI12_RS03690	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
GZI12_RS03740	ENOG4107R88	Chemotaxis protein (CheV)
GZI12_RS03745	ENOG4105BZU	Histidine kinase
GZI12_RS03750	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
GZI12_RS03755	ENOG4108ZC9	flagellar basal-body rod protein flgc
GZI12_RS03760	ENOG4105W00	Flagellar hook capping protein
GZI12_RS03765	ENOG4105BZE	flagellar hook protein, FlgE
GZI12_RS03770	ENOG4108KPB	Flagellar basal-body rod protein FlgF
GZI12_RS03775	ENOG4105CGA	flagellar basal-body rod protein FlgG
GZI12_RS03780	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
GZI12_RS03785	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
GZI12_RS03790	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
GZI12_RS03800	ENOG4105DTJ	flagellar hook-associated protein
GZI12_RS03805	ENOG4105I03	Flagellin
GZI12_RS03810	ENOG4105I03	Flagellin
GZI12_RS03945	ENOG4105C3G	gtp-binding protein
GZI12_RS03950	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
GZI12_RS03955	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
GZI12_RS03960	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
GZI12_RS03970	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
GZI12_RS03980	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
GZI12_RS03985	ENOG4108YY7	Invasion gene expression up-regulator SirB
GZI12_RS03995	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
GZI12_RS04000	ENOG4105CGH	5'-nucleotidase
GZI12_RS04005	ENOG4108Z66	YbaK ebsC protein
GZI12_RS04010	ENOG4105C2W	permease
GZI12_RS04025	ENOG4105CS1	NAD(P)H quinone oxidoreductase
GZI12_RS04030	ENOG4105K89	arsenate reductase
GZI12_RS04035	ENOG4105ERG	peptidase m48, ste24p
GZI12_RS04050	ENOG4105C8Q	Methyl-accepting chemotaxis
GZI12_RS04055	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GZI12_RS04060	ENOG4105RH4	Glycine cleavage system transcriptional repressor
GZI12_RS04070	ENOG4107EG0	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
GZI12_RS04075	ENOG4105D3Y	Na H antiporter
GZI12_RS04080	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
GZI12_RS04085	ENOG4105EIY	sodium-type flagellar protein motY
GZI12_RS04095	ENOG4108UYE	Lactoylglutathione lyase
GZI12_RS04100	ENOG4105CSM	endonuclease III
GZI12_RS04115	ENOG4105D6A	Electron transport complex
GZI12_RS04125	ENOG4108R3D	Electron transport complex
GZI12_RS04135	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
GZI12_RS04145	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
GZI12_RS04150	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GZI12_RS04160	ENOG4105CHW	UPF0052 protein
GZI12_RS04165	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
GZI12_RS04170	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
GZI12_RS04180	ENOG4105M00	molybdopterin converting factor, subunit 1
GZI12_RS04185	ENOG4108ZAF	Molybdopterin
GZI12_RS04205	ENOG4107SXA	Phosphorylase
GZI12_RS04225	ENOG4105D1F	ATP-binding protein
GZI12_RS04230	ENOG4105DBI	uridine monophosphokinase
GZI12_RS04235	ENOG4108GAE	asmA family
GZI12_RS04240	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
GZI12_RS04250	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
GZI12_RS04255	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
GZI12_RS04260	ENOG4107Z0K	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
GZI12_RS04270	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
GZI12_RS04275	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
GZI12_RS04280	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
GZI12_RS04285	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
GZI12_RS04305	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
GZI12_RS04310	ENOG4105M2J	Glutaredoxin
GZI12_RS04315	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
GZI12_RS04325	ENOG4105DGU	Histone deacetylase
GZI12_RS04330	ENOG4105BZU	Histidine kinase
GZI12_RS04335	ENOG41073TP	transcriptional regulator
GZI12_RS04345	ENOG4105CTX	dehydratase
GZI12_RS04355	ENOG4105CXK	mandelate racemase muconate lactonizing
GZI12_RS04360	ENOG4107QZF	nitrite reductase NADPH large subunit
GZI12_RS04365	ENOG4105WZK	nitrite reductase NADPH small subunit
GZI12_RS04375	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
GZI12_RS04410	ENOG4106V8H	Nucleoid-associated protein
GZI12_RS04420	ENOG4105DFD	Na H antiporter
GZI12_RS04425	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
GZI12_RS04430	ENOG41073TP	transcriptional regulator
GZI12_RS04435	ENOG4105EYW	Ion transport protein
GZI12_RS04440	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
GZI12_RS04445	ENOG4105C0A	alcohol dehydrogenase
GZI12_RS04455	ENOG4107QMS	site-determining protein
GZI12_RS04470	ENOG4105CVE	Lytic murein transglycosylase
GZI12_RS04475	ENOG4105EJC	lysr family transcriptional regulator
GZI12_RS04480	ENOG4105D9N	nucleoside
GZI12_RS04485	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
GZI12_RS04510	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
GZI12_RS04545	ENOG4105D50	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity)
GZI12_RS04550	ENOG4105R8A	Heat shock protein
GZI12_RS04555	ENOG4105CYM	Glutathione S-transferase
GZI12_RS04565	ENOG4105CNG	UPF0061 protein
GZI12_RS04575	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
GZI12_RS04580	ENOG4105EHG	Permease protein
GZI12_RS04590	ENOG4106GFD	transport protein
GZI12_RS04595	ENOG41090AP	transport protein
GZI12_RS04600	ENOG4105WQ5	TonB family
GZI12_RS04605	ENOG4105D4P	Coproporphyrinogen iii oxidase
GZI12_RS04610	ENOG41090JE	Utilization Protein
GZI12_RS04615	ENOG4105PYN	Pyridoxamine 5-phosphate oxidase-related
GZI12_RS04620	ENOG4105D05	Receptor
GZI12_RS04625	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
GZI12_RS04630	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
GZI12_RS04635	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
GZI12_RS04645	ENOG4105K70	DNA-binding protein
GZI12_RS04655	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
GZI12_RS04660	ENOG4105CAT	Cytidine monophosphate kinase
GZI12_RS04665	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
GZI12_RS04670	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
GZI12_RS04675	ENOG4105Q4A	inner membrane protein yciS
GZI12_RS04680	ENOG4105CFV	Tetratricopeptide repeat protein
GZI12_RS04685	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
GZI12_RS04690	ENOG4105FR9	TRNA-(Ms 2 io 6 A)-hydroxylase
GZI12_RS04700	ENOG4107R11	Transcriptional regulator
GZI12_RS04715	ENOG4105C7J	ABC transporter, permease
GZI12_RS04720	ENOG4108JJB	ABC transporter
GZI12_RS04725	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
GZI12_RS04735	ENOG4106RHG	Yeca family
GZI12_RS04740	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
GZI12_RS04745	ENOG4105D1H	recombination factor protein RarA
GZI12_RS04750	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
GZI12_RS04765	ENOG4105EIF	outer membrane protein W
GZI12_RS04770	ENOG4105HDK	L-asparaginase
GZI12_RS04775	ENOG4105D07	Signal peptide peptidase, SppA
GZI12_RS04780	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
GZI12_RS04790	ENOG4105CIY	formyltetrahydrofolate deformylase
GZI12_RS04800	ENOG4105DVT	helicase
GZI12_RS04805	ENOG41072GX	Peptidase M22 Glycoprotease
GZI12_RS04820	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
GZI12_RS04825	ENOG4105CEY	Amp-dependent synthetase and ligase
GZI12_RS04830	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
GZI12_RS04835	ENOG4105C1J	atp-dependent rna helicase
GZI12_RS04840	ENOG4105CHH	sulfate transporter
GZI12_RS04845	ENOG4105C03	ribonuclease
GZI12_RS04850	ENOG4105EI2	Pseudouridine synthase
GZI12_RS04860	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
GZI12_RS04870	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
GZI12_RS04875	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
GZI12_RS04880	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
GZI12_RS04885	ENOG4105CHR	reductase
GZI12_RS04890	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
GZI12_RS04895	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
GZI12_RS04900	ENOG4105YAZ	4-amino-4-deoxychorismate lyase
GZI12_RS04905	ENOG4105HHA	aminodeoxychorismate lyase
GZI12_RS04910	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
GZI12_RS04915	ENOG4107QRG	dna polymerase iii
GZI12_RS04920	ENOG4105F8V	Hydrolase, tatD family
GZI12_RS04925	ENOG4105CI1	PTS System
GZI12_RS04955	ENOG4108NRW	Phospholipase, patatin family
GZI12_RS04970	ENOG4105C0B	DNA polymerase III (alpha subunit)
GZI12_RS04985	ENOG4105UBK	short-chain dehydrogenase reductase
GZI12_RS04990	ENOG4105ERU	peptidase
GZI12_RS05010	ENOG4105D2N	Aldolase
GZI12_RS05015	ENOG4105CE4	GlcNAc 6-P deacetylase
GZI12_RS05020	ENOG4108YTN	IIa component
GZI12_RS05025	ENOG4105F3R	pts system mannose fructose sorbose family iid
GZI12_RS05035	ENOG4108RG5	PTS system N-acetylgalactosamine-specific transporter subunit IIB
GZI12_RS05040	ENOG4105E70	isomerase
GZI12_RS05045	ENOG4105C6Q	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
GZI12_RS05050	ENOG4105E98	transcriptional regulator DeoR family
GZI12_RS05060	ENOG4105E98	transcriptional regulator DeoR family
GZI12_RS05075	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
GZI12_RS05080	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
GZI12_RS05095	ENOG4105JQN	Transcriptional regulator
GZI12_RS05100	ENOG4105DK2	UPF0207 protein
GZI12_RS05105	ENOG4105CHM	Aminotransferase
GZI12_RS05110	ENOG4105E4F	Isochorismate synthase
GZI12_RS05115	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
GZI12_RS05120	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
GZI12_RS05125	ENOG4108IPT	Naphthoate synthase
GZI12_RS05135	ENOG4105CEY	Amp-dependent synthetase and ligase
GZI12_RS05140	ENOG4105HMI	Membrane
GZI12_RS05145	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
GZI12_RS05170	ENOG4105C29	acyl-CoA thioesterase
GZI12_RS05190	ENOG4105BZU	Histidine kinase
GZI12_RS05215	ENOG4105EST	Metal Dependent Phosphohydrolase
GZI12_RS05220	ENOG4105F88	accessory colonization factor AcfD
GZI12_RS05235	ENOG4105BZU	Histidine kinase
GZI12_RS05240	ENOG4105CBN	LysR family transcriptional regulator
GZI12_RS05245	ENOG4105EMU	Dehydrogenase
GZI12_RS05250	ENOG4107QSI	ABC, transporter
GZI12_RS05255	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
GZI12_RS05260	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
GZI12_RS05265	ENOG4105C3U	ABC transporter
GZI12_RS05270	ENOG4108JQ7	(ABC) transporter
GZI12_RS05275	ENOG4105CHF	Glutathione S-transferase
GZI12_RS05285	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
GZI12_RS05290	ENOG4105BZS	acriflavin resistance protein
GZI12_RS05300	ENOG4107PU6	Membrane
GZI12_RS05305	ENOG4108DNC	Involved in acetate metabolism (By similarity)
GZI12_RS05310	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
GZI12_RS05320	ENOG4105DCF	alanine dehydrogenase
GZI12_RS05330	ENOG4105CNU	cell division protein FtsK
GZI12_RS05335	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
GZI12_RS05345	ENOG4105C05	Multifunctional regulator of fatty acid metabolism (By similarity)
GZI12_RS05350	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
GZI12_RS05355	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
GZI12_RS05360	ENOG4108JUA	Transcriptional regulator
GZI12_RS05370	ENOG4105C8Q	Methyl-accepting chemotaxis
GZI12_RS05375	ENOG4105K59	histidine triad (HIT) protein
GZI12_RS05400	ENOG4105D0Y	UPF0227 protein
GZI12_RS05405	ENOG4105CEP	NADH dehydrogenase
GZI12_RS05420	ENOG4108JA2	transcriptioN-repair coupling factor
GZI12_RS05430	ENOG4105D60	lipoprotein releasing system transmembrane protein
GZI12_RS05435	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
GZI12_RS05440	ENOG4105D60	lipoprotein releasing system transmembrane protein
GZI12_RS05450	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
GZI12_RS05455	ENOG4105BZ1	(ABC) transporter
GZI12_RS05460	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
GZI12_RS05465	ENOG4105W49	UPF0434 protein
GZI12_RS05470	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
GZI12_RS05490	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
GZI12_RS05500	ENOG4108ZNS	ferredoxin-type protein NapF
GZI12_RS05510	ENOG4105WH1	Two component transcriptional regulator luxr family
GZI12_RS05515	ENOG4105ED1	spovr family
GZI12_RS05520	ENOG4106AKX	UPF0229 protein
GZI12_RS05525	ENOG4105CYN	Serine protein kinase
GZI12_RS05535	ENOG4105XWI	UPF0304 protein
GZI12_RS05550	ENOG4105F1A	Pyruvate formate-lyase
GZI12_RS05560	ENOG4105C6N	Formate acetyltransferase
GZI12_RS05570	ENOG4108JEH	abc transporter atp-binding protein
GZI12_RS05575	ENOG4106TNF	Periplasmic binding protein
GZI12_RS05580	ENOG4105DSP	amino acid AbC transporter
GZI12_RS05585	ENOG4106YG3	ABC transporter
GZI12_RS05590	ENOG4108VAC	response regulator
GZI12_RS05595	ENOG4108HRK	Histidine kinase
GZI12_RS05610	ENOG4105D60	lipoprotein releasing system transmembrane protein
GZI12_RS05615	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
GZI12_RS05635	ENOG4108Z33	Thiol disulfide Interchange Protein
GZI12_RS05645	ENOG4105CFG	Acts as a chaperone (By similarity)
GZI12_RS05650	ENOG4105CFG	Acts as a chaperone (By similarity)
GZI12_RS05660	ENOG4105BZU	Histidine kinase
GZI12_RS05670	ENOG4108N3W	hemolysin secretion protein
GZI12_RS05695	ENOG4105CQ7	ATP-dependent helicase
GZI12_RS05710	ENOG4108HPI	phosphatidate Cytidylyltransferase
GZI12_RS05725	ENOG4105CK2	sodium dicarboxylate symporter
GZI12_RS05730	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
GZI12_RS05735	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
GZI12_RS05740	ENOG4105DK0	Indole-3-glycerol phosphate synthase
GZI12_RS05745	ENOG4108I0Q	anthranilate phosphoribosyltransferase
GZI12_RS05750	ENOG4105DDQ	anthranilate synthase
GZI12_RS05755	ENOG4105CRQ	synthase (Component I)
GZI12_RS05765	ENOG4105DB7	PHP domain protein
GZI12_RS05770	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
GZI12_RS05775	ENOG4105FE9	pseudouridine synthase
GZI12_RS05785	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
GZI12_RS05790	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
GZI12_RS05795	ENOG4105BZU	Histidine kinase
GZI12_RS05805	ENOG4105DZ0	fad dependent oxidoreductase
GZI12_RS05810	ENOG4108Z4U	Ferredoxin
GZI12_RS05815	ENOG4108RWN	rrna methyltransferase
GZI12_RS05835	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
GZI12_RS05840	ENOG4105C8Y	Acetylornithine aminotransferase
GZI12_RS05845	ENOG4105C26	Dehydrogenase
GZI12_RS05850	ENOG4108RYR	transcriptional regulator AsnC family
GZI12_RS05855	ENOG4105ENR	peptidase, M24
GZI12_RS05860	ENOG4108JJ8	(ABC) transporter
GZI12_RS05865	ENOG4108JJ9	ABC, transporter
GZI12_RS05870	ENOG4105C3M	thioredoxin reductase
GZI12_RS05880	ENOG4105C9B	Cysteine desulfurase
GZI12_RS05895	ENOG4107GZ4	SanA protein
GZI12_RS05905	ENOG4107R1I	NAD-dependent malic enzyme
GZI12_RS05920	ENOG4105CGF	Aromatic amino acid aminotransferase
GZI12_RS05930	ENOG4105C5S	asparaginyl-tRNA synthetase
GZI12_RS05935	ENOG4105C8Q	Methyl-accepting chemotaxis
GZI12_RS05940	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
GZI12_RS05950	ENOG4105EJQ	L-serine dehydratase
GZI12_RS05955	ENOG4105C44	Serine transporter
GZI12_RS05960	ENOG4105P8F	nudix hydrolase
GZI12_RS05970	ENOG4105BZU	Histidine kinase
GZI12_RS05990	ENOG4105CM6	amino acid regulated cytosolic protein
GZI12_RS05995	ENOG4106K28	UPF0283 membrane protein
GZI12_RS06000	ENOG4108JU8	Transcriptional regulator
GZI12_RS06005	ENOG4105D9U	N-acetyltransferase
GZI12_RS06020	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
GZI12_RS06050	ENOG4105EAQ	(twin-arginine translocation) pathway signal
GZI12_RS06055	ENOG4105C5X	domain protein
GZI12_RS06070	ENOG4105CH5	extracellular solute-binding protein, family 7
GZI12_RS06080	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
GZI12_RS06095	ENOG4108RMU	ferritin dps family protein
GZI12_RS06100	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
GZI12_RS06125	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
GZI12_RS06145	ENOG4105S8Q	sugar efflux transporter
GZI12_RS06150	ENOG4106TD9	Diguanylate cyclase
GZI12_RS06155	ENOG4105EB3	Histidine kinase
GZI12_RS06170	ENOG4105CFI	type iii restriction protein res subunit
GZI12_RS06175	ENOG4105I08	Pseudouridine synthase
GZI12_RS06180	ENOG4105C2C	drug resistance transporter, Bcr CflA
GZI12_RS06190	ENOG4105F27	Major Facilitator
GZI12_RS06195	ENOG410642W	LysR family Transcriptional regulator
GZI12_RS06210	ENOG4105EHV	domain protein
GZI12_RS06230	ENOG4105D9U	N-acetyltransferase
GZI12_RS06235	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
GZI12_RS06250	ENOG4105DWP	Membrane
GZI12_RS06255	ENOG4105CPC	Aldo Keto reductase
GZI12_RS06260	ENOG4105CGD	Nad-dependent epimerase dehydratase
GZI12_RS06265	ENOG4105UQX	Mate efflux family protein
GZI12_RS06270	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
GZI12_RS06285	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
GZI12_RS06290	ENOG4105KCK	Peptidoglycan-associated lipoprotein
GZI12_RS06310	ENOG4105D3D	Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine (By similarity)
GZI12_RS06350	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
GZI12_RS06355	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
GZI12_RS06365	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GZI12_RS06370	ENOG410829K	Lysine exporter protein (Lyse ygga)
GZI12_RS06385	ENOG4105G0K	glycine radical enzyme YjjI family
GZI12_RS06390	ENOG41076CZ	activating enzyme
GZI12_RS06415	ENOG41064T2	transcriptional regulator, lysR family
GZI12_RS06430	ENOG4105C8V	SAICAR synthetase
GZI12_RS06440	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
GZI12_RS06455	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
GZI12_RS06460	ENOG4105JJR	Histidine kinase
GZI12_RS06465	ENOG4105E0K	tonB-dependent siderophore receptor
GZI12_RS06485	ENOG4109015	Biopolymer transport protein exbD tolR
GZI12_RS06500	ENOG4105DRP	amino acid AbC transporter
GZI12_RS06505	ENOG4106TNF	Periplasmic binding protein
GZI12_RS06510	ENOG4105E5Q	amino acid AbC transporter
GZI12_RS06515	ENOG4105CDA	abc transporter atp-binding protein
GZI12_RS06570	ENOG4108MJI	response regulator
GZI12_RS06575	ENOG4105WN5	stage II sporulation protein
GZI12_RS06635	ENOG4107RAN	Peptidase, M16
GZI12_RS06645	ENOG4105CQ0	ABC transporter
GZI12_RS06660	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
GZI12_RS06675	ENOG4105EVB	acetyltransferase
GZI12_RS06705	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GZI12_RS06735	ENOG4105CE4	GlcNAc 6-P deacetylase
GZI12_RS06740	ENOG41061DF	Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P (By similarity)
GZI12_RS06750	ENOG4108ERU	trap dicarboxylate transporter subunit DctP
GZI12_RS06760	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
GZI12_RS06770	ENOG4106KNT	transcriptional regulator
GZI12_RS06775	ENOG4108MX5	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses (By similarity)
GZI12_RS06780	ENOG4108MX5	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses (By similarity)
GZI12_RS06805	ENOG4107EFR	Flavocytochrome c
GZI12_RS06850	ENOG4108R6K	riboflavin synthase, subunit alpha
GZI12_RS06875	ENOG4105C8Q	Methyl-accepting chemotaxis
GZI12_RS06880	ENOG4105CHR	reductase
GZI12_RS06890	ENOG4106IUH	DTW domain containing protein
GZI12_RS06905	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
GZI12_RS06910	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
GZI12_RS06920	ENOG4107A5B	Binding-protein-dependent transport systems, inner membrane component
GZI12_RS06930	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GZI12_RS06935	ENOG4105BZU	Histidine kinase
GZI12_RS06940	ENOG4108MA4	Peptidase M66
GZI12_RS06955	ENOG4105C5H	ABC transporter
GZI12_RS06960	ENOG4105C8Q	Methyl-accepting chemotaxis
GZI12_RS07000	ENOG4105QAX	Iron-sulfur
GZI12_RS07015	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
GZI12_RS07025	ENOG4107RUE	extracellular solute-binding protein family 1
GZI12_RS07040	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
GZI12_RS07060	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
GZI12_RS07065	ENOG4105Q9Y	Universal stress protein
GZI12_RS07070	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
GZI12_RS07085	ENOG4105C59	p-type ATPase
GZI12_RS07095	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
GZI12_RS07110	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
GZI12_RS07195	ENOG4105DAN	ATP-dependent protease
GZI12_RS07200	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
GZI12_RS07235	ENOG4108T7E	Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity)
GZI12_RS07245	ENOG4105C7I	Dehydrogenase
GZI12_RS07270	ENOG41073DY	may be a structural element that influences the osmotic activation of ProP at a post-translational level (By similarity)
GZI12_RS07275	ENOG4108ZGC	gaf domain protein
GZI12_RS07280	ENOG4105BZ1	(ABC) transporter
GZI12_RS07295	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
GZI12_RS07315	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
GZI12_RS07325	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
GZI12_RS07330	ENOG4107QXX	ABC transporter
GZI12_RS07335	ENOG4105EZ7	amino acid ABC transporter
GZI12_RS07340	ENOG4105DRP	amino acid AbC transporter
GZI12_RS07345	ENOG4105CDA	abc transporter atp-binding protein
GZI12_RS07350	ENOG4108MN8	Membrane
GZI12_RS07355	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
GZI12_RS07360	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
GZI12_RS07365	ENOG4105C8Q	Methyl-accepting chemotaxis
GZI12_RS07400	ENOG4105KCK	Peptidoglycan-associated lipoprotein
GZI12_RS07415	ENOG4105BZU	Histidine kinase
GZI12_RS07425	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
GZI12_RS07430	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
GZI12_RS07435	ENOG4105C8Q	Methyl-accepting chemotaxis
GZI12_RS07460	ENOG4107KET	secretion protein, HlyD family
GZI12_RS07480	ENOG4105CVG	Homoserine O-transsuccinylase
GZI12_RS07485	ENOG41090FY	type IV pilus biogenesis stability protein PilW
GZI12_RS07490	ENOG4105EBA	Specifically methylates the adenine in position 1618 of 23S rRNA (By similarity)
GZI12_RS07510	ENOG4105C5A	transporter
GZI12_RS07515	ENOG4106NZI	LysR family Transcriptional regulator
GZI12_RS07535	ENOG41080WI	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system (By similarity)
GZI12_RS07540	ENOG4108IU2	vtamin B12-transporter permease
GZI12_RS07545	ENOG4107UI5	Transforms N(2)-succinylglutamate into succinate and glutamate (By similarity)
GZI12_RS07565	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
GZI12_RS07570	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
GZI12_RS07575	ENOG4107RT4	flavin reductase domain protein
GZI12_RS07590	ENOG4105VEQ	Cold shock protein
GZI12_RS07605	ENOG4105CJB	Exodeoxyribonuclease I
GZI12_RS07610	ENOG4105VAW	lrga family
GZI12_RS07625	ENOG4105CPI	Metal Dependent Phosphohydrolase
GZI12_RS07635	ENOG4105BZU	Histidine kinase
GZI12_RS07640	ENOG4105C8P	)-transporter
GZI12_RS07645	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
GZI12_RS07650	ENOG4105FQ6	thiopurine methyltransferase
GZI12_RS07665	ENOG4108N23	SpoOM-related protein
GZI12_RS07680	ENOG4106PMH	Extracellular solute-binding protein family 3
GZI12_RS07690	ENOG4105DMR	ABC, transporter
GZI12_RS07715	ENOG4105CDV	Ompa motb domain protein
GZI12_RS07735	ENOG4108RXX	maleylacetoacetate isomerase
GZI12_RS07745	ENOG4105F1J	Homogentisate 1,2-dioxygenase
GZI12_RS07750	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
GZI12_RS07755	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
GZI12_RS07770	ENOG4105EP1	Efflux transporter rnd family, mfp subunit
GZI12_RS07775	ENOG4108IJF	Heavy metal efflux pump, CzcA
GZI12_RS07805	ENOG4105DWU	Membrane
GZI12_RS07815	ENOG4105DY8	decarboxylase
GZI12_RS07820	ENOG4106KNT	transcriptional regulator
GZI12_RS07830	ENOG41090BQ	Glutaredoxin
GZI12_RS07835	ENOG4105D0C	transport protein
GZI12_RS07840	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
GZI12_RS07845	ENOG4105DZ2	Transcriptional regulator
GZI12_RS07860	ENOG4105CCT	upf0313 protein
GZI12_RS07905	ENOG4105BZG	amino acid carrier protein
GZI12_RS07920	ENOG4107RX3	Mg2 transporter protein cora family protein
GZI12_RS07925	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
GZI12_RS07990	ENOG4105DAS	pts system
GZI12_RS07995	ENOG4105ETZ	PTS System
GZI12_RS08000	ENOG4105F3R	pts system mannose fructose sorbose family iid
GZI12_RS08010	ENOG4108Y83	glucose-6-phosphate isomerase
GZI12_RS08085	ENOG4108QUJ	UPF0174 protein YaaW
GZI12_RS08190	ENOG4105D9N	nucleoside
GZI12_RS08205	ENOG4105CEY	Amp-dependent synthetase and ligase
GZI12_RS08220	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GZI12_RS08225	ENOG4105BZU	Histidine kinase
GZI12_RS08245	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
GZI12_RS08255	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
GZI12_RS08290	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
GZI12_RS08335	ENOG4105DQS	Transcriptional regulator
GZI12_RS08355	ENOG4108K3A	Glutathione S-transferase
GZI12_RS08370	ENOG410901P	UPF0249 protein
GZI12_RS08375	ENOG4108UW5	maltose o-acetyltransferase
GZI12_RS08380	ENOG4108YYQ	gCN5-related N-acetyltransferase
GZI12_RS08390	ENOG4107QI1	Mate efflux family protein
GZI12_RS08405	ENOG4105WBN	Transcriptional regulator (LacI family
GZI12_RS08410	ENOG4105D7K	pfkb domain protein
GZI12_RS08415	ENOG4107R3K	hydrolase
GZI12_RS08425	ENOG4105C5Y	PTS System
GZI12_RS08430	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
GZI12_RS08435	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
GZI12_RS08480	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
GZI12_RS08485	ENOG4105WH1	Two component transcriptional regulator luxr family
GZI12_RS08495	ENOG4105CQ2	DNA polymerase
GZI12_RS08500	ENOG4105CK1	PTS System
GZI12_RS08510	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
GZI12_RS08515	ENOG4108W5H	UPF0263 protein
GZI12_RS08520	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
GZI12_RS08525	ENOG4105BZU	Histidine kinase
GZI12_RS08530	ENOG4105BZU	Histidine kinase
GZI12_RS08545	ENOG4105NAU	thioesterase Superfamily protein
GZI12_RS08550	ENOG4105K9H	YciI-like protein
GZI12_RS08565	ENOG4105XZD	Fe-S protein
GZI12_RS08575	ENOG4105VNH	ABC transporter solute-binding protein
GZI12_RS08580	ENOG4105CXZ	ABC transporter, permease
GZI12_RS08585	ENOG4108VGW	abc transporter atp-binding protein
GZI12_RS08590	ENOG4108T9J	Cdp-alcohol phosphatidyltransferase
GZI12_RS08600	ENOG4108W1A	pseudouridine synthase
GZI12_RS08615	ENOG4105C28	cystathionine
GZI12_RS08620	ENOG4108R3E	Dna-3-methyladenine glycosylase i
GZI12_RS08635	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
GZI12_RS08645	ENOG4105YYT	phage shock protein B
GZI12_RS08650	ENOG41087YS	Phage shock protein A
GZI12_RS08655	ENOG4105E51	psp operon transcriptional activator
GZI12_RS08660	ENOG4108J59	Extracellular solute-binding protein, family 5
GZI12_RS08665	ENOG4108EKA	peptide transport system, permease
GZI12_RS08670	ENOG4108EU3	peptide transport system, permease
GZI12_RS08675	ENOG4108JQ3	Peptide ABC transporter ATP-binding protein
GZI12_RS08680	ENOG4108JQ2	peptide transport system atp-binding protein
GZI12_RS08690	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
GZI12_RS08700	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
GZI12_RS08705	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
GZI12_RS08725	ENOG4105CIH	Imidazole acetol-phosphate transaminase
GZI12_RS08730	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
GZI12_RS08735	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
GZI12_RS08740	ENOG4107S6Z	Na H antiporter
GZI12_RS08750	ENOG4107RE1	Inosine-guanosine kinase
GZI12_RS08765	ENOG41075W9	High frequency lysogenization protein HflD homolog
GZI12_RS08770	ENOG4107QTF	adenylosuccinate lyase
GZI12_RS08790	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
GZI12_RS08805	ENOG4105DTD	Dehydrogenase
GZI12_RS08815	ENOG4105D0M	Protease HtpX homolog
GZI12_RS08820	ENOG4105EWW	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
GZI12_RS08825	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
GZI12_RS08830	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
GZI12_RS08835	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
GZI12_RS08840	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
GZI12_RS08865	ENOG4108URS	primosomal replication protein n''
GZI12_RS08870	ENOG4106428	Protein of unknown function (DUF2496)
GZI12_RS08875	ENOG4105CGK	Exodeoxyribonuclease III
GZI12_RS08880	ENOG4105RKW	reductase (By
GZI12_RS08885	ENOG4107QPN	acyl-Coa dehydrogenase
GZI12_RS08890	ENOG41067SE	Tetr family transcriptional regulator
GZI12_RS08910	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
GZI12_RS08915	ENOG41062D9	Histidine kinase
GZI12_RS08930	ENOG4108I0N	Transporter, RarD family, DMT superfamily protein
GZI12_RS08935	ENOG4105CA0	peroxidase
GZI12_RS08950	ENOG4107RZC	phospholipase d
GZI12_RS08965	ENOG4107KGK	dmso reductase anchor subunit
GZI12_RS08970	ENOG4105QAX	Iron-sulfur
GZI12_RS08985	ENOG4105C2I	pirin domain protein
GZI12_RS09025	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
GZI12_RS09050	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
GZI12_RS09070	ENOG4107RUE	extracellular solute-binding protein family 1
GZI12_RS09075	ENOG4105CJP	fad dependent oxidoreductase
GZI12_RS09095	ENOG4105C44	Serine transporter
GZI12_RS09100	ENOG4105CEM	UPF0597 protein
GZI12_RS09105	ENOG4108XM1	transcriptional regulator AsnC family
GZI12_RS09110	ENOG4107SYB	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
GZI12_RS09170	ENOG4108RNS	Exports L-alanine (By similarity)
GZI12_RS09205	ENOG4105UFD	tol-pal system protein YbgF
GZI12_RS09210	ENOG4105KCK	Peptidoglycan-associated lipoprotein
GZI12_RS09215	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
GZI12_RS09225	ENOG4105M8F	Biopolymer transport protein exbD tolR
GZI12_RS09230	ENOG4105E02	MotA TolQ exbB proton channel
GZI12_RS09235	ENOG4107YD3	Thioesterase
GZI12_RS09250	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
GZI12_RS09255	ENOG4105C4M	(Ubiquinol oxidase) subunit I
GZI12_RS09260	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
GZI12_RS09270	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
GZI12_RS09275	ENOG4108J2R	molybdopterin oxidoreductase
GZI12_RS09295	ENOG4105TMB	Formate nitrite transporter
GZI12_RS09320	ENOG4107SRH	Nad-dependent epimerase dehydratase
GZI12_RS09325	ENOG4107DB1	DUF218 domain
GZI12_RS09330	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
GZI12_RS09335	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
GZI12_RS09340	ENOG4105VEQ	Cold shock protein
GZI12_RS09350	ENOG4108R99	pseudouridine synthase
GZI12_RS09355	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
GZI12_RS09365	ENOG4108KHP	Diguanylate cyclase
GZI12_RS09380	ENOG41081XQ	Conserved Protein
GZI12_RS09385	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
GZI12_RS09395	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
GZI12_RS09415	ENOG4105DUC	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division (By similarity)
GZI12_RS09420	ENOG4105DAH	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity)
GZI12_RS09425	ENOG4105GHU	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity (By similarity)
GZI12_RS09430	ENOG4106371	Methyltransferase
GZI12_RS09435	ENOG4107S90	membrAne
GZI12_RS09440	ENOG4106WF9	DNA-binding transcriptional regulator TorR
GZI12_RS09450	ENOG4105ETE	Transcriptional regulator (LacI family
GZI12_RS09455	ENOG4105HP8	regulator of competence-specific genes
GZI12_RS09470	ENOG4105F2Z	3-oxoadipate enol-lactonase
GZI12_RS09475	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
GZI12_RS09485	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
GZI12_RS09490	ENOG4105RKX	Protein of unknown function (DUF2498)
GZI12_RS09515	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
GZI12_RS09530	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
GZI12_RS09535	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
GZI12_RS09540	ENOG4105D58	Diguanylate phosphodiesterase
GZI12_RS09550	ENOG4105VUT	cytoplasmic protein
GZI12_RS09560	ENOG4105E0X	reductase
GZI12_RS09565	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
GZI12_RS09570	ENOG4105DSB	aldose 1-epimerase
GZI12_RS09575	ENOG4105DHI	Methyltransferase
GZI12_RS09590	ENOG4105C94	Transporter
GZI12_RS09625	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
GZI12_RS09630	ENOG4105C4M	(Ubiquinol oxidase) subunit I
GZI12_RS09635	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
GZI12_RS09645	ENOG4108ZZ3	UPF0260 protein
GZI12_RS09650	ENOG4105Y3U	Transglycosylase-associated protein
GZI12_RS09655	ENOG4105KRS	Proteinase inhibitor
GZI12_RS09665	ENOG4105KME	endoribonuclease L-psp
GZI12_RS09670	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
GZI12_RS09680	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
GZI12_RS09685	ENOG4107QMP	dna polymerase iii subunits gamma and tau
GZI12_RS09690	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
GZI12_RS09695	ENOG4105WD1	Membrane
GZI12_RS09700	ENOG4105I93	response regulator
GZI12_RS09705	ENOG4105EJC	lysr family transcriptional regulator
GZI12_RS09710	ENOG41069NU	Nitroreductase
GZI12_RS09715	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
GZI12_RS09720	ENOG4107QY8	reductase
GZI12_RS09725	ENOG4105CUW	cytochrome C-TYPE protein
GZI12_RS09730	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
GZI12_RS09735	ENOG4105CHU	acetyl-coa acetyltransferase
GZI12_RS09740	ENOG4105EMN	RNA polymerase sigma factor
GZI12_RS09750	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
GZI12_RS09755	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
GZI12_RS09760	ENOG410903C	(LipO)protein
GZI12_RS09770	ENOG4108M1T	Cytochrome c-type biogenesis protein
GZI12_RS09775	ENOG4107QX9	Thiol disulfide interChange protein
GZI12_RS09780	ENOG4105DA4	cytochrome c-type biogenesis protein
GZI12_RS09785	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
GZI12_RS09795	ENOG41060IM	Heme exporter protein
GZI12_RS09800	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
GZI12_RS09805	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
GZI12_RS09815	ENOG4108V3W	Chemotaxis protein, CheW
GZI12_RS09825	ENOG4107QJE	Chromosome Partitioning Protein
GZI12_RS09840	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
GZI12_RS09845	ENOG4108VYJ	response regulator receiver protein
GZI12_RS09850	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GZI12_RS09860	ENOG4105FZW	flagellar biosynthesis regulator FlhF
GZI12_RS09865	ENOG4105D7B	Flagellar biosynthesis protein flha
GZI12_RS09870	ENOG4108BY2	phosphohistidine phosphatase
GZI12_RS09875	ENOG4107VK2	coenzyme PQQ biosynthesis protein PqqF
GZI12_RS09880	ENOG4106ZCM	YecM protein
GZI12_RS09885	ENOG4105C75	arginyL-tRNA synthetase
GZI12_RS09900	ENOG4105CE1	Ferrous iron transport protein b
GZI12_RS09905	ENOG4105XFK	Ferrous iron transport protein A
GZI12_RS09915	ENOG4105NXV	High-affinity zinc uptake system protein
GZI12_RS09920	ENOG4105FDK	ABC transporter
GZI12_RS09925	ENOG4105FAV	ABC, transporter
GZI12_RS09930	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
GZI12_RS09935	ENOG4105E96	Colicin v production protein
GZI12_RS09940	ENOG4108S3P	Sporulation domain protein
GZI12_RS09945	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
GZI12_RS09965	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
GZI12_RS09970	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
GZI12_RS09975	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
GZI12_RS09980	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
GZI12_RS09985	ENOG4105MH2	YfcL protein
GZI12_RS10005	ENOG4105EN6	Membrane
GZI12_RS10015	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
GZI12_RS10020	ENOG4108DG9	Smr protein MutS2
GZI12_RS10025	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
GZI12_RS10030	ENOG4105D00	flagellar biosynthetic protein flhB
GZI12_RS10035	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
GZI12_RS10040	ENOG4105VS8	Flagellar biosynthetic protein fliq
GZI12_RS10045	ENOG4105CN7	Flagellar biosynthetic protein FliP
GZI12_RS10050	ENOG4105K0P	flagellar biosynthesis protein
GZI12_RS10055	ENOG4105DD5	Flagellar motor switch protein
GZI12_RS10060	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
GZI12_RS10080	ENOG4108JIR	Flagellum-specific ATP synthase
GZI12_RS10090	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
GZI12_RS10095	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
GZI12_RS10100	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
GZI12_RS10110	ENOG4105BZU	Histidine kinase
GZI12_RS10120	ENOG4105MQ3	flagellar protein FliS
GZI12_RS10130	ENOG4107BRV	flagellar capping protein
GZI12_RS10135	ENOG41063QE	flagellar protein FlaG
GZI12_RS10140	ENOG4105I03	Flagellin
GZI12_RS10145	ENOG4105I03	Flagellin
GZI12_RS10150	ENOG4105I03	Flagellin
GZI12_RS10155	ENOG4105EZR	dyp-type peroxidase family protein
GZI12_RS10160	ENOG4105QZU	Inner membrane protein YfeZ
GZI12_RS10175	ENOG4105KUZ	arsenate reductase
GZI12_RS10200	ENOG4105EXF	Zn-ribbon-containing, possibly nucleic-acid-binding protein
GZI12_RS10205	ENOG4108T6E	Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function (By similarity)
GZI12_RS10210	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
GZI12_RS10220	ENOG4105BZU	Histidine kinase
GZI12_RS10225	ENOG4105EWT	decarboxylase family
GZI12_RS10230	ENOG4105CIQ	May have a role in processing of nucleic acids. It is probably not an exonuclease
GZI12_RS10240	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
GZI12_RS10245	ENOG4105M08	Membrane
GZI12_RS10255	ENOG4105ETT	transcriptional Regulator, LysR family
GZI12_RS10265	ENOG4107XSU	flagellar motor protein motb
GZI12_RS10270	ENOG4105E14	MotA TolQ exbB proton channel
GZI12_RS10275	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
GZI12_RS10280	ENOG4105CTB	Polyprenyl synthetase
GZI12_RS10290	ENOG4105DR9	pseudouridine synthase
GZI12_RS10295	ENOG4105DR9	pseudouridine synthase
GZI12_RS10320	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
GZI12_RS10330	ENOG4105C7S	Dehydrogenase
GZI12_RS10335	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
GZI12_RS10340	ENOG4105E33	succinate dehydrogenase
GZI12_RS10345	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
GZI12_RS10350	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
GZI12_RS10355	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
GZI12_RS10360	ENOG4105BZN	citrate synthase
GZI12_RS10365	ENOG4107QNR	UPF0135 protein
GZI12_RS10375	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
GZI12_RS10380	ENOG4107CDU	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity)
GZI12_RS10385	ENOG4105EV9	Alpha Beta Hydrolase
GZI12_RS10395	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
GZI12_RS10405	ENOG41090R7	Ferric uptake
GZI12_RS10410	ENOG4105CX6	glutaminyL-tRNA synthetase
GZI12_RS10415	ENOG4105CI1	PTS System
GZI12_RS10420	ENOG4105CE4	GlcNAc 6-P deacetylase
GZI12_RS10425	ENOG4105E2R	ROK family
GZI12_RS10435	ENOG4105CAQ	asparagine synthetase
GZI12_RS10440	ENOG4105DUX	Transporter
GZI12_RS10460	ENOG4108DG9	Smr protein MutS2
GZI12_RS10465	ENOG4105FE9	pseudouridine synthase
GZI12_RS10470	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
GZI12_RS10475	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
GZI12_RS10480	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
GZI12_RS10505	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
GZI12_RS10510	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
GZI12_RS10515	ENOG4108Z6B	deaminase
GZI12_RS10525	ENOG4105CFC	Transporter
GZI12_RS10555	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
GZI12_RS10560	ENOG4105CFG	Acts as a chaperone (By similarity)
GZI12_RS10570	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
GZI12_RS10580	ENOG4108KB2	LysR family Transcriptional regulator
GZI12_RS10585	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
GZI12_RS10590	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
GZI12_RS10595	ENOG4105VDB	UPF0125 protein
GZI12_RS10600	ENOG4108Z1B	Cyclase dehydrase
GZI12_RS10605	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
GZI12_RS10615	ENOG4105DFP	Integrase
GZI12_RS10645	ENOG4105CVR	type I restriction-modification system
GZI12_RS10675	ENOG4105E98	transcriptional regulator DeoR family
GZI12_RS10685	ENOG4107QW4	alcohol dehydrogenase
GZI12_RS10695	ENOG4107S6Z	Na H antiporter
GZI12_RS10700	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
GZI12_RS10730	ENOG4105DGM	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
GZI12_RS10735	ENOG4105CY0	Metallo-Beta-Lactamase
GZI12_RS10740	ENOG4105CKW	Inner membrane protein yedI
GZI12_RS10745	ENOG4108IQK	o-acetylhomoserine
GZI12_RS10750	ENOG4105BZG	amino acid carrier protein
GZI12_RS10755	ENOG4106HK8	GPR1 FUN34 yaaH family protein
GZI12_RS10760	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
GZI12_RS10765	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
GZI12_RS10770	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
GZI12_RS10785	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
GZI12_RS10790	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
GZI12_RS10795	ENOG4105N21	Membrane
GZI12_RS10820	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
GZI12_RS10825	ENOG4105CUZ	uba thif-type nad fad binding protein
GZI12_RS10830	ENOG4105CA3	membrane-bound lytic murein transglycosylase
GZI12_RS10850	ENOG4107QYX	exodeoxyribonuclease v alpha
GZI12_RS10855	ENOG4107QKA	exodeoxyribonuclease V beta
GZI12_RS10860	ENOG4105DSY	exodeoxyribonuclease V, gamma
GZI12_RS10870	ENOG4105DUM	transcriptional regulator, lysR family
GZI12_RS10875	ENOG4105X2V	dna damage-inducible protein
GZI12_RS10880	ENOG4105BZS	acriflavin resistance protein
GZI12_RS10885	ENOG410624X	efflux transporter, rnd family, mfp subunit
GZI12_RS10910	ENOG4106N3A	copper homeostasis protein cutc
GZI12_RS10940	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
GZI12_RS10945	ENOG4105E2Z	phosphate ABC transporter (Permease
GZI12_RS10950	ENOG4105C8U	phosphate abc transporter
GZI12_RS10955	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
GZI12_RS10960	ENOG4105C9X	ppx gppa phosphatase
GZI12_RS10965	ENOG4105DJH	phosphate
GZI12_RS10970	ENOG4105BZU	Histidine kinase
GZI12_RS10975	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
GZI12_RS10985	ENOG4105CFP	Peptidase U32
GZI12_RS10990	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
GZI12_RS11000	ENOG4105HPZ	Involved in the removal of murein from the sacculus. May also facilitate integration of nascent murein strands into the sacculus by cleaving the peptide bonds between neighboring strands in mature murein (By similarity)
GZI12_RS11010	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
GZI12_RS11015	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
GZI12_RS11020	ENOG4105VIE	preprotein translocase, subunit YajC
GZI12_RS11030	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
GZI12_RS11035	ENOG4105W87	Cbs domain
GZI12_RS11040	ENOG4108I9X	Isocitrate lyase
GZI12_RS11050	ENOG4105C5Q	Transcriptional regulator
GZI12_RS11055	ENOG4105D3R	alkyl hydroperoxide reductase
GZI12_RS11070	ENOG4105EJ3	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity)
GZI12_RS11075	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
GZI12_RS11090	ENOG4105UQX	Mate efflux family protein
GZI12_RS11110	ENOG4108IQE	Amp-dependent synthetase and ligase
GZI12_RS11115	ENOG4105ETT	transcriptional Regulator, LysR family
GZI12_RS11120	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
GZI12_RS11125	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
GZI12_RS11145	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
GZI12_RS11160	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
GZI12_RS11165	ENOG4105D9N	nucleoside
GZI12_RS11170	ENOG4105EYA	deoxyribonuclease
GZI12_RS11175	ENOG4105D1Q	UPF0246 protein
GZI12_RS11180	ENOG4105BZG	amino acid carrier protein
GZI12_RS11190	ENOG4107XGZ	Hydrolase
GZI12_RS11195	ENOG4105XEP	YhcH YjgK YiaL family protein
GZI12_RS11205	ENOG4105P66	Membrane
GZI12_RS11215	ENOG4108UHU	Aldolase
GZI12_RS11220	ENOG4107SS6	2-dehydro-3-deoxygluconokinase
GZI12_RS11230	ENOG4105DEI	Mannitol dehydrogenase
GZI12_RS11235	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
GZI12_RS11240	ENOG4105XDZ	Tripartite ATP-independent periplasmic transporter
GZI12_RS11245	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
GZI12_RS11250	ENOG4105C6F	GntR Family Transcriptional Regulator
GZI12_RS11255	ENOG4105CHZ	Catalyzes the dehydration of D-mannonate (By similarity)
GZI12_RS11265	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
GZI12_RS11270	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
GZI12_RS11275	ENOG4108VKA	Acts as a radical domain for damaged PFL and possibly other radical proteins (By similarity)
GZI12_RS11280	ENOG4108M1A	Chitin-binding protein
GZI12_RS11285	ENOG4105VP0	transcriptional regulator, lysR family
GZI12_RS11290	ENOG4105EJ9	Membrane
GZI12_RS11295	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
GZI12_RS11300	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
GZI12_RS11305	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
GZI12_RS11315	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
GZI12_RS11325	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
GZI12_RS11330	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
GZI12_RS11335	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
GZI12_RS11340	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
GZI12_RS11345	ENOG4105DFU	Cell wall formation (By similarity)
GZI12_RS11350	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
GZI12_RS11360	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
GZI12_RS11370	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
GZI12_RS11375	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
GZI12_RS11380	ENOG4105CJN	penicillin-binding protein
GZI12_RS11385	ENOG41063Y6	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
GZI12_RS11390	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
GZI12_RS11400	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
GZI12_RS11415	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
GZI12_RS11420	ENOG4105W4M	Transport-associated protein
GZI12_RS11425	ENOG4105KB2	stringent starvation protein b
GZI12_RS11430	ENOG4107MKT	Stringent starvation protein a
GZI12_RS11435	ENOG4105EIX	cytochrome c1
GZI12_RS11440	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
GZI12_RS11445	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
GZI12_RS11450	ENOG4108UJD	30S ribosomal protein S9
GZI12_RS11455	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
GZI12_RS11460	ENOG4105D6Z	AFG1 family ATPase
GZI12_RS11465	ENOG4108W2Q	Cytochrome d ubiquinol oxidase subunit III
GZI12_RS11470	ENOG4105C0H	protease
GZI12_RS11480	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GZI12_RS11485	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GZI12_RS11490	ENOG4105IPS	esterase
GZI12_RS11495	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
GZI12_RS11500	ENOG4108SX3	cytoplasmic protein
GZI12_RS11505	ENOG41087AY	ADP-Ribose pyrophosphatase
GZI12_RS11510	ENOG4105DFG	type I secretion outer membrane protein
GZI12_RS11515	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
GZI12_RS11520	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
GZI12_RS11525	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
GZI12_RS11530	ENOG4105CHV	Transcription elongation factor NusA
GZI12_RS11535	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
GZI12_RS11550	ENOG4105NTZ	Preprotein translocase subunit SecG
GZI12_RS11555	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
GZI12_RS11560	ENOG4105EEI	dihydropteroate synthase
GZI12_RS11565	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
GZI12_RS11570	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
GZI12_RS11580	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
GZI12_RS11585	ENOG4107QE9	Inherit from COG: Membrane
GZI12_RS11590	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
GZI12_RS11600	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
GZI12_RS11605	ENOG4105DR5	peptidase
GZI12_RS11620	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
GZI12_RS11625	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
GZI12_RS11630	ENOG4105IPI	Membrane
GZI12_RS11635	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
GZI12_RS11645	ENOG4107QRA	Extracellular solute-binding protein, family 5
GZI12_RS11655	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
GZI12_RS11660	ENOG4105C3U	ABC transporter
GZI12_RS11665	ENOG4108JQ7	(ABC) transporter
GZI12_RS11675	ENOG4105RD7	BadF BadG BcrA BcrD
GZI12_RS11680	ENOG4105E2D	ec 3.2.1.52
GZI12_RS11690	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
GZI12_RS11695	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
GZI12_RS11700	ENOG4108I5D	sulfate abc transporter
GZI12_RS11715	ENOG4108YZA	Nitrogen regulatory protein pii
GZI12_RS11720	ENOG4105XTV	UPF0231 protein
GZI12_RS11725	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
GZI12_RS11730	ENOG4105BZW	Glycerate kinase
GZI12_RS11735	ENOG4107QIJ	Aconitate hydratase 2
GZI12_RS11740	ENOG4105D78	K07001 NTE family protein
GZI12_RS11745	ENOG4105BZ4	penicillin-binding protein
GZI12_RS11750	ENOG4105CQ7	ATP-dependent helicase
GZI12_RS11755	ENOG4105PW4	Sugar fermentation stimulation protein homolog
GZI12_RS11765	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
GZI12_RS11770	ENOG4105DJ0	Poly(A) Polymerase
GZI12_RS11775	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GZI12_RS11780	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
GZI12_RS11785	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
GZI12_RS11790	ENOG4105E3A	(ABC) transporter
GZI12_RS11795	ENOG4105DA5	(ABC) transporter
GZI12_RS11805	ENOG41077A9	carbonic anhydrase
GZI12_RS11810	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
GZI12_RS11815	ENOG410630P	Transcriptional regulator
GZI12_RS11820	ENOG4107QN2	dihydrolipoyl dehydrogenase
GZI12_RS11825	ENOG4107QSN	dihydrolipoamide acetyltransferase
GZI12_RS11830	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
GZI12_RS11835	ENOG41073TP	transcriptional regulator
GZI12_RS11840	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
GZI12_RS11845	ENOG4105T95	Thiol disulfide interChange protein
GZI12_RS11855	ENOG41071R3	Low-potential electron donor to a number of redox enzymes (By similarity)
GZI12_RS11865	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
GZI12_RS11870	ENOG4108K5H	permease YjgP YjgQ family protein
GZI12_RS11875	ENOG4108M8S	permease YjgP YjgQ family protein
GZI12_RS11880	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
GZI12_RS11885	ENOG4105MYG	DNA polymerase iii, chi subunit
GZI12_RS11895	ENOG4105C5I	Dehydrogenase
GZI12_RS11900	ENOG4105D3G	Pseudouridine synthase
GZI12_RS11905	ENOG4105K3M	)-transporter
GZI12_RS11910	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
GZI12_RS11915	ENOG4108IAB	Phoh family
GZI12_RS11920	ENOG4105DBV	ornithine carbamoyltransferase
GZI12_RS11925	ENOG4105CXT	aspartate transcarbamylase
GZI12_RS11930	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
GZI12_RS11935	ENOG4105KME	endoribonuclease L-psp
GZI12_RS11940	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
GZI12_RS11945	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
GZI12_RS11955	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
GZI12_RS11965	ENOG4105NWN	ApaG protein
GZI12_RS11970	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
GZI12_RS11980	ENOG4107XM3	UPF0442 protein
GZI12_RS11985	ENOG4105DWK	Membrane
GZI12_RS11990	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GZI12_RS12000	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
GZI12_RS12005	ENOG4105EAH	synthase
GZI12_RS12015	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
GZI12_RS12020	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
GZI12_RS12025	ENOG4105H1G	trap transporter solute receptor taxi family
GZI12_RS12060	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
GZI12_RS12085	ENOG4105VQ7	Rod shape-determining protein MreD
GZI12_RS12200	ENOG41062P1	Diguanylate cyclase phosphodiesterase
GZI12_RS12205	ENOG4108UUM	single-stranded DNA-binding protein
GZI12_RS12215	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
GZI12_RS12220	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
GZI12_RS12230	ENOG4105C5R	Aminotransferase
GZI12_RS12235	ENOG4105CFH	Aspartokinase
GZI12_RS12240	ENOG4105CZX	twitching motility protein
GZI12_RS12245	ENOG4105CZX	twitching motility protein
GZI12_RS12250	ENOG4105DFA	alanine racemase domain protein
GZI12_RS12255	ENOG4105II7	pyrroline-5-carboxylate reductase
GZI12_RS12260	ENOG4108VIA	integral membrane protein
GZI12_RS12265	ENOG4105VZ9	UPF0235 protein
GZI12_RS12275	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
GZI12_RS12280	ENOG4105CSA	Coproporphyrinogen iii oxidase
GZI12_RS12285	ENOG4105CSV	Glutaminase
GZI12_RS12290	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
GZI12_RS12295	ENOG4105CEN	a g-specific adenine glycosylase
GZI12_RS12300	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
GZI12_RS12305	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
GZI12_RS12360	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
GZI12_RS12365	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
GZI12_RS12370	ENOG4105VFK	BolA family
GZI12_RS12380	ENOG4105E3I	toluene tolerance
GZI12_RS12385	ENOG4107PE3	Mammalian cell entry related domain protein
GZI12_RS12390	ENOG4105CY3	ABC transporter, permease
GZI12_RS12395	ENOG4105DHJ	ABC, transporter
GZI12_RS12405	ENOG4105C2X	Arabinose 5-phosphate isomerase
GZI12_RS12410	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
GZI12_RS12420	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
GZI12_RS12425	ENOG4108IUZ	ABC transporter
GZI12_RS12430	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GZI12_RS12435	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
GZI12_RS12440	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
GZI12_RS12445	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
GZI12_RS12450	ENOG41080Z8	PHOSPHOCARRIER protein
GZI12_RS12455	ENOG4105CJW	magnesium transporter
GZI12_RS12550	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
GZI12_RS12560	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
GZI12_RS12700	ENOG4105MYN	Zinc uptake regulation protein
GZI12_RS12710	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
GZI12_RS12720	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
GZI12_RS12725	ENOG4105C11	sulfate adenylyltransferase), subunit 2
GZI12_RS12730	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
GZI12_RS12735	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
GZI12_RS12745	ENOG4107YB6	acetyltransferase, (GNAT) family
GZI12_RS12750	ENOG4105DFI	Membrane
GZI12_RS12755	ENOG4108UBT	opacity-associated protein
GZI12_RS12760	ENOG4108V1T	peptidylprolyl cis-trans isomerase
GZI12_RS12770	ENOG4108ZT0	50S ribosomal protein l17
GZI12_RS12775	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
GZI12_RS12780	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
GZI12_RS12785	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
GZI12_RS12800	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
GZI12_RS12805	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
GZI12_RS12810	ENOG4105VPB	50S ribosomal protein L30
GZI12_RS12815	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
GZI12_RS12825	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
GZI12_RS12830	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
GZI12_RS12835	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
GZI12_RS12840	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GZI12_RS12845	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
GZI12_RS12850	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
GZI12_RS12855	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
GZI12_RS12860	ENOG41083MP	50s ribosomal protein l29
GZI12_RS12865	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
GZI12_RS12870	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
GZI12_RS12875	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
GZI12_RS12885	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GZI12_RS12890	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
GZI12_RS12895	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
GZI12_RS12900	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
GZI12_RS12905	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
GZI12_RS12910	ENOG4105C2N	RNA methyltransferase TrmH family group 3
GZI12_RS12915	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
GZI12_RS12920	ENOG4107SYB	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
GZI12_RS12925	ENOG4108UV7	flagellar protein motX
GZI12_RS12930	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
GZI12_RS12935	ENOG4108YZY	peptidylprolyl cis-trans isomerase
GZI12_RS12950	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
GZI12_RS12955	ENOG4105C5H	ABC transporter
GZI12_RS12965	ENOG4105DNZ	Alpha Beta Hydrolase
GZI12_RS12970	ENOG4105YP7	UPF0270 protein
GZI12_RS12980	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
GZI12_RS12990	ENOG4105C26	Dehydrogenase
GZI12_RS13005	ENOG4105DDQ	anthranilate synthase
GZI12_RS13020	ENOG4105DJV	ribulose-phosphate 3-epimerase
GZI12_RS13025	ENOG4105DFE	Dna adenine methylase
GZI12_RS13035	ENOG4105D49	3-dehydroquinate synthase
GZI12_RS13040	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
GZI12_RS13045	ENOG4105E4G	Type IV pilus
GZI12_RS13070	ENOG4108JQC	penicillin-binding protein 1A
GZI12_RS13080	ENOG4105EHV	domain protein
GZI12_RS13090	ENOG4108JU3	Alkyl hydroperoxide reductase
GZI12_RS13095	ENOG4105D3R	alkyl hydroperoxide reductase
GZI12_RS13105	ENOG4105CDH	Citrulline--aspartate ligase
GZI12_RS13110	ENOG4105CAS	nag kinase
GZI12_RS13115	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
GZI12_RS13120	ENOG4105CWC	Acetylornithine deacetylase
GZI12_RS13125	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
GZI12_RS13130	ENOG4105U3E	Transcriptional regulator
GZI12_RS13135	ENOG4105D7W	serine acetyltransferase
GZI12_RS13140	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
GZI12_RS13145	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
GZI12_RS13150	ENOG4107YZP	Rhodanese domain protein
GZI12_RS13180	ENOG4105E33	succinate dehydrogenase
GZI12_RS13185	ENOG4108WJH	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
GZI12_RS13190	ENOG4108VP9	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
GZI12_RS13200	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
GZI12_RS13210	ENOG4105CMR	udp-glucose 4-epimerase
GZI12_RS13220	ENOG4105ETE	Transcriptional regulator (LacI family
GZI12_RS13225	ENOG4105C25	Primosomal protein n'
GZI12_RS13230	ENOG4105VFB	Binds the 23S rRNA (By similarity)
GZI12_RS13235	ENOG4105C6K	Malic enzyme
GZI12_RS13245	ENOG4105C28	cystathionine
GZI12_RS13250	ENOG4105CFH	Aspartokinase
GZI12_RS13255	ENOG4105SYT	Methylenetetrahydrofolate reductase
GZI12_RS13260	ENOG41065UX	Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA (By similarity)
GZI12_RS13265	ENOG4105CBT	Fructose-1,6-bisphosphatase
GZI12_RS13280	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
GZI12_RS13295	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
GZI12_RS13370	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
GZI12_RS13380	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
GZI12_RS13385	ENOG4105FAW	cDP-glucose 4,6-dehydratase
GZI12_RS13390	ENOG4105EJZ	Glucose-1-phosphate cytidylyltransferase
GZI12_RS13420	ENOG4105F0R	Cytidylyltransferase
GZI12_RS13445	ENOG4107SE4	UDP-N-acetylglucosamine 2-epimerase
GZI12_RS13450	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
GZI12_RS13460	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
GZI12_RS13470	ENOG4105NWR	lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase
GZI12_RS13480	ENOG4108RT4	succinoglycan biosynthesis
GZI12_RS13485	ENOG4106WTF	Glycosyl transferase, family 2
GZI12_RS13495	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
GZI12_RS13500	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
GZI12_RS13505	ENOG4105DKP	glycosyl transferase, family 9
GZI12_RS13510	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
GZI12_RS13530	ENOG4108I6E	Sulfatase
GZI12_RS13540	ENOG4105KDC	50s ribosomal protein l28
GZI12_RS13545	ENOG4105W5Q	DNA repair protein (RadC
GZI12_RS13550	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
GZI12_RS13555	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
GZI12_RS13560	ENOG4105D1S	lipid A biosynthesis
GZI12_RS13565	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
GZI12_RS13575	ENOG4105DSJ	YicC domain protein
GZI12_RS13585	ENOG4105C7N	Xanthine uracil vitamin C permease
GZI12_RS13600	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
GZI12_RS13605	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
GZI12_RS13610	ENOG4105CB5	ATP-dependent DNA helicase recG
GZI12_RS13615	ENOG4105E2D	ec 3.2.1.52
GZI12_RS13620	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
GZI12_RS13625	ENOG4107RK2	ADP-ribose diphosphatase NudE
GZI12_RS13635	ENOG4105MJ2	Competence protein
GZI12_RS13640	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
GZI12_RS13650	ENOG4105BZM	domain protein
GZI12_RS13655	ENOG4108RRZ	Transcription elongation factor GreB
GZI12_RS13665	ENOG4105E0F	Histidine kinase
GZI12_RS13675	ENOG4105U1E	general secretion pathway protein M
GZI12_RS13680	ENOG4108BY5	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins (By similarity)
GZI12_RS13685	ENOG4108RTD	type II secretion system protein K
GZI12_RS13690	ENOG4108WWZ	General secretion pathway protein J
GZI12_RS13695	ENOG4105X5Z	General secretion pathway protein I
GZI12_RS13705	ENOG4108VAU	general secretion pathway protein G
GZI12_RS13710	ENOG4105D7Q	type ii secretion system
GZI12_RS13715	ENOG4107QHF	type ii secretion system protein e
GZI12_RS13725	ENOG4108XKW	General secretion pathway protein C
GZI12_RS13730	ENOG4105VEJ	Heat shock protein
GZI12_RS13735	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
GZI12_RS13740	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
GZI12_RS13750	ENOG4105SUU	thioesterase domain
GZI12_RS13760	ENOG4107S2Z	UPF0761 membrane protein
GZI12_RS13770	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
GZI12_RS13775	ENOG4105CI3	gtp-binding protein typa
GZI12_RS13780	ENOG4105C5F	glutamine synthetase
GZI12_RS13790	ENOG4105CUX	Signal transduction histidine kinase
GZI12_RS13795	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GZI12_RS13800	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
GZI12_RS13875	ENOG4108Z0R	Transferase
GZI12_RS13880	ENOG4105SG3	Protein of unknown function (DUF1488)
GZI12_RS13885	ENOG4105E2X	shikimate dehydrogenase
GZI12_RS13890	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
GZI12_RS13895	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
GZI12_RS13900	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
GZI12_RS13910	ENOG4108WI1	Dna topoisomerase
GZI12_RS13915	ENOG4108RPN	Protein smg homolog
GZI12_RS13920	ENOG4105C79	DNA protecting protein DprA
GZI12_RS13925	ENOG4108WZM	domain protein
GZI12_RS13930	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
GZI12_RS13935	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
GZI12_RS13940	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
GZI12_RS13945	ENOG4105C1A	potassium transporter peripheral membrane
GZI12_RS13950	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
GZI12_RS13955	ENOG4108UT2	hemolysin iii
GZI12_RS13960	ENOG4108N23	SpoOM-related protein
GZI12_RS13965	ENOG4105PC1	Conserved Protein
GZI12_RS13975	ENOG4105E27	serine threonine protein kinase
GZI12_RS13980	ENOG4108Z33	Thiol disulfide Interchange Protein
GZI12_RS13985	ENOG4106HNH	Acyl-transferase
GZI12_RS13995	ENOG4105C0P	Mg chelatase subunit ChlI
GZI12_RS14005	ENOG4105P3Y	Acetolactate synthase 2 regulatory subunit
GZI12_RS14010	ENOG4105CM2	brancheD-chain amino acid aminotransferase
GZI12_RS14020	ENOG4105C7B	Threonine dehydratase
GZI12_RS14025	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
GZI12_RS14035	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
GZI12_RS14065	ENOG4105JKW	Valine--pyruvate aminotransferase
GZI12_RS14070	ENOG4108ZNX	Heat shock protein
GZI12_RS14075	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GZI12_RS14080	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
GZI12_RS14085	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
GZI12_RS14100	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
GZI12_RS14105	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
GZI12_RS14110	ENOG4105ETU	transcriptional activator (TenA
GZI12_RS14115	ENOG4107Z6I	Thiamine biosynthesis protein
GZI12_RS14120	ENOG4105Y36	Binding-protein-dependent transport systems, inner membrane component
GZI12_RS14125	ENOG4108YI8	ABC transporter
GZI12_RS14130	ENOG4105DWF	phosphomethylpyrimidine kinase
GZI12_RS14140	ENOG4108JQ7	(ABC) transporter
GZI12_RS14160	ENOG4105CDY	transcriptional regulatory protein
GZI12_RS14170	ENOG4105Y49	secretion protein, HlyD family
GZI12_RS14180	ENOG4108IEG	Formate dehydrogenase Alpha subunit
GZI12_RS14190	ENOG4105C8Q	Methyl-accepting chemotaxis
GZI12_RS14200	ENOG4108YYI	Protein of unknown function (DUF2810)
GZI12_RS14205	ENOG41086KC	Transcriptional regulator
GZI12_RS14235	ENOG4105C26	Dehydrogenase
GZI12_RS14240	ENOG4105E0U	tyrosine-specific transport protein
GZI12_RS14245	ENOG4105CH6	catalase
GZI12_RS14255	ENOG4105N0V	mono-oxygenase ydhR
GZI12_RS14270	ENOG4105CR4	methylisocitrate lyase
GZI12_RS14275	ENOG4105BZN	citrate synthase
GZI12_RS14280	ENOG4108I0Z	Aconitate hydratase
GZI12_RS14285	ENOG4105C7F	AcnD-accessory protein PrpF
GZI12_RS14290	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
GZI12_RS14295	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
GZI12_RS14300	ENOG4105BZS	acriflavin resistance protein
GZI12_RS14310	ENOG4105EJC	lysr family transcriptional regulator
GZI12_RS14340	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
GZI12_RS14345	ENOG4105P66	Membrane
GZI12_RS14350	ENOG410667J	hydrolase
GZI12_RS14395	ENOG4107SSZ	Phosphatase
GZI12_RS14405	ENOG4105DM4	PTS System
GZI12_RS14410	ENOG4105DE4	1-phosphofructokinase
GZI12_RS14415	ENOG4105DTZ	bifunctional PTS system fructose-specific transporter subunit IIA HPr protein
GZI12_RS14420	ENOG4107B7Y	DNA-binding transcriptional regulator FruR
GZI12_RS14430	ENOG4105GZI	Transcriptional regulator
GZI12_RS14435	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
GZI12_RS14450	ENOG4105CA0	peroxidase
GZI12_RS14460	ENOG4107RF4	Phosphodiesterase
GZI12_RS14465	ENOG4105CS2	ec 3.2.1.21
GZI12_RS14485	ENOG41061ZR	Transcriptional regulator
GZI12_RS14490	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
GZI12_RS14495	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
GZI12_RS14500	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
GZI12_RS14505	ENOG4105WJG	Glutathione
GZI12_RS14530	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
GZI12_RS14535	ENOG4105C8P	)-transporter
GZI12_RS14545	ENOG4105CYW	agmatinase
GZI12_RS14550	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
GZI12_RS14565	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
GZI12_RS14570	ENOG4105C6N	Formate acetyltransferase
GZI12_RS14595	ENOG4105C1J	atp-dependent rna helicase
GZI12_RS14605	ENOG4105DN9	Na H antiporter
GZI12_RS14610	ENOG41074DU	domain protein
GZI12_RS14615	ENOG4108P2H	Inner membrane protein YjiG
GZI12_RS14630	ENOG4105CK2	sodium dicarboxylate symporter
GZI12_RS14635	ENOG4108UPT	UPF0178 protein
GZI12_RS14640	ENOG4108YZN	class I peptide chain release factor
GZI12_RS14645	ENOG4105DP0	ferredoxin-NADP reductase
GZI12_RS14655	ENOG4105RA2	Membrane
GZI12_RS14660	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
GZI12_RS14670	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
GZI12_RS14675	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
GZI12_RS14695	ENOG4108Q67	UPF0319 protein
GZI12_RS14700	ENOG4108JJA	ABC, transporter
GZI12_RS14715	ENOG4107QZV	Type I secretion membrane fusion protein
GZI12_RS14730	ENOG4105E6M	Sulphatase-modifying factor protein
GZI12_RS14745	ENOG4105C26	Dehydrogenase
GZI12_RS14755	ENOG4105CK7	Sodium proline symporter
GZI12_RS14765	ENOG4105BZ1	(ABC) transporter
GZI12_RS14775	ENOG4105YE1	PilZ domain
GZI12_RS14785	ENOG4108MK9	spermidine N(1)-acetyltransferase
GZI12_RS14800	ENOG4108JJB	ABC transporter
GZI12_RS14810	ENOG4105EFX	secretion protein, HlyD family
GZI12_RS14815	ENOG4105KK7	inner membrane protein YiaW
GZI12_RS14820	ENOG4106TD9	Diguanylate cyclase
GZI12_RS14840	ENOG4107SEY	Conserved Protein
GZI12_RS14845	ENOG4108XDN	Transcriptional regulator
GZI12_RS14850	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
GZI12_RS14855	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
GZI12_RS14865	ENOG4107QWP	ABC-2 type transporter
GZI12_RS14870	ENOG4105CJ1	ABC, transporter
GZI12_RS14880	ENOG4107YBY	Hydrolase
GZI12_RS14885	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
GZI12_RS14895	ENOG4105C1J	atp-dependent rna helicase
GZI12_RS14900	ENOG4105CXK	mandelate racemase muconate lactonizing
GZI12_RS14910	ENOG4107EFR	Flavocytochrome c
GZI12_RS14915	ENOG4108WYP	Transcriptional regulator
GZI12_RS14920	ENOG4105DWD	nucleoside recognition domain protein
GZI12_RS14960	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
GZI12_RS14965	ENOG4105EDR	glucose galactose transporter
GZI12_RS14975	ENOG4108RVA	ribokinase
GZI12_RS14980	ENOG4105ETE	Transcriptional regulator (LacI family
GZI12_RS14990	ENOG4105C1J	atp-dependent rna helicase
GZI12_RS15020	ENOG4107YWA	deoxycytidylate deaminase
GZI12_RS15025	ENOG4105DZC	cytosine deaminase
GZI12_RS15040	ENOG4108RS6	transposase
GZI12_RS15045	ENOG4105EKE	dihydroorotase
GZI12_RS15070	ENOG4105BZU	Histidine kinase
GZI12_RS15105	ENOG4107QWR	cellulase (EC 3.2.1.4)
GZI12_RS15110	ENOG4105BZU	Histidine kinase
GZI12_RS15125	ENOG4108FN7	Aldo keto reductase
GZI12_RS15140	ENOG4105FDP	GntR family transcriptional regulator
GZI12_RS15145	ENOG4105CI1	PTS System
GZI12_RS15195	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
GZI12_RS15200	ENOG4108NRW	Phospholipase, patatin family
GZI12_RS15250	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
GZI12_RS15255	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
GZI12_RS15265	ENOG4105CK7	Sodium proline symporter
GZI12_RS15270	ENOG4107QW4	alcohol dehydrogenase
GZI12_RS15275	ENOG4105DFI	Membrane
GZI12_RS15280	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
GZI12_RS15290	ENOG4107EJG	GntR family transcriptional regulator
GZI12_RS15295	ENOG4105CHR	reductase
GZI12_RS15325	ENOG4105DZ2	Transcriptional regulator
GZI12_RS15330	ENOG4107RJ1	sodium solute
GZI12_RS15345	ENOG4105EY3	heparinase II III family protein
GZI12_RS15350	ENOG4105EY3	heparinase II III family protein
GZI12_RS15355	ENOG4105M5J	Cupin 2, conserved barrel domain protein
GZI12_RS15360	ENOG4107SS6	2-dehydro-3-deoxygluconokinase
GZI12_RS15365	ENOG4108UHU	Aldolase
GZI12_RS15370	ENOG4105CK7	Sodium proline symporter
GZI12_RS15395	ENOG4108ESY	Metal dependent phosphohydrolase
GZI12_RS15420	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
GZI12_RS15430	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
GZI12_RS15435	ENOG4105ETE	Transcriptional regulator (LacI family
GZI12_RS15440	ENOG4105F8D	glycoside hydrolase family 4
GZI12_RS15445	ENOG4105VCP	PTS System
GZI12_RS15450	ENOG4105CK1	PTS System
GZI12_RS15460	ENOG4105C8Q	Methyl-accepting chemotaxis
GZI12_RS15470	ENOG4105EMF	GntR family transcriptional regulator
GZI12_RS15480	ENOG4108RTU	Aldolase
GZI12_RS15495	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
GZI12_RS15500	ENOG4105CXK	mandelate racemase muconate lactonizing
GZI12_RS15505	ENOG4105C01	Dihydroxy-acid dehydratase
GZI12_RS15520	ENOG4108I6A	alcohol dehydrogenase
GZI12_RS15525	ENOG4108RU0	short-chain dehydrogenase reductase
GZI12_RS15555	ENOG4105C94	Transporter
GZI12_RS15560	ENOG4105BZU	Histidine kinase
GZI12_RS15575	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
GZI12_RS15595	ENOG4105CCF	Lysine exporter protein (Lyse ygga)
GZI12_RS15620	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
GZI12_RS15635	ENOG4108R6F	Surfeit locus 1 family protein
GZI12_RS15645	ENOG4107SGF	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
GZI12_RS15650	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
GZI12_RS15665	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
GZI12_RS15670	ENOG4107RGM	aldo keto reductase
GZI12_RS15685	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
GZI12_RS15755	ENOG4105CR8	Transcriptional regulator
GZI12_RS15765	ENOG4105DKW	ABC transporter
GZI12_RS15770	ENOG4107S6Z	Na H antiporter
GZI12_RS15800	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
GZI12_RS15810	ENOG4107QY8	reductase
GZI12_RS15815	ENOG4105QAX	Iron-sulfur
GZI12_RS15820	ENOG4107KGK	dmso reductase anchor subunit
GZI12_RS15825	ENOG4108NEM	leader-binding protein dmsD
GZI12_RS15835	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
GZI12_RS15840	ENOG4105WRB	Hydrogenase assembly chaperone hypC hupF
GZI12_RS15845	ENOG4105CQS	hydrogenase expression formation protein HypD
GZI12_RS15850	ENOG4105C45	hydrogenase expression formation protein (HypE)
GZI12_RS15855	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
GZI12_RS15860	ENOG4105E3S	small subunit
GZI12_RS15865	ENOG4105DPX	Hydrogenase, large subunit
GZI12_RS15870	ENOG4105X7T	Ni Fe-hydrogenase, b-type cytochrome subunit
GZI12_RS15875	ENOG4108USZ	hydrogenase
GZI12_RS15900	ENOG4108EU3	peptide transport system, permease
GZI12_RS15905	ENOG4108RZA	ABC transporter
GZI12_RS15910	ENOG4105EFJ	Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity)
GZI12_RS15925	ENOG4105VEQ	Cold shock protein
GZI12_RS16015	ENOG4105DVH	amino acid
GZI12_RS16030	ENOG4105EE0	oxidoreductase
GZI12_RS16035	ENOG4108UKZ	OsmC family
GZI12_RS16045	ENOG4105BZU	Histidine kinase
GZI12_RS16060	ENOG4107QVM	von Willebrand factor, type A
GZI12_RS16075	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
GZI12_RS16085	ENOG4105D5U	fad dependent oxidoreductase
GZI12_RS16125	ENOG4108XW0	May be a transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype. It can also activate genes such as sodA, zwf and micF
GZI12_RS16130	ENOG4105DM4	PTS System
GZI12_RS16140	ENOG4105EIP	mannose-6-phosphate isomerase
GZI12_RS16145	ENOG4105DM4	PTS System
GZI12_RS16150	ENOG4106R3P	AraC family transcriptional regulator
GZI12_RS16160	ENOG4108YRF	PTS System
GZI12_RS16165	ENOG4105DM4	PTS System
GZI12_RS16175	ENOG4105C8U	phosphate abc transporter
GZI12_RS16180	ENOG4105E2Z	phosphate ABC transporter (Permease
GZI12_RS16205	ENOG4107TIF	Phenazine biosynthesis protein, PhzF family
GZI12_RS16210	ENOG4105EXG	Transcriptional regulator
GZI12_RS16215	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
GZI12_RS16220	ENOG4105CPQ	Dehydrogenase
GZI12_RS16295	ENOG4108Z24	l-2,4-diaminobutyric acid acetyltransferase
GZI12_RS16325	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
GZI12_RS16335	ENOG4108KAZ	Involved in phosphonate degradation (By similarity)
GZI12_RS16340	ENOG4108JPW	Aminotransferase
GZI12_RS16345	ENOG4107STF	Involved in phosphonate degradation (By similarity)
GZI12_RS16350	ENOG4105CJP	fad dependent oxidoreductase
GZI12_RS16355	ENOG4105ETT	transcriptional Regulator, LysR family
GZI12_RS16370	ENOG4107RCV	ABC transporter, permease
GZI12_RS16395	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
GZI12_RS16400	ENOG4108K1J	Transporter DctQ
GZI12_RS16405	ENOG4108KJ1	Trap dicarboxylate transporter, dctp subunit
GZI12_RS16420	ENOG4105CI1	PTS System
GZI12_RS16435	ENOG4108JPW	Aminotransferase
GZI12_RS16440	ENOG4108Z6K	Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant (By similarity)
GZI12_RS16445	ENOG4105CZK	Aspartate kinase
GZI12_RS16450	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
GZI12_RS16460	ENOG4107QX8	SPFH domain, Band 7 family protein
GZI12_RS16520	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
GZI12_RS16540	ENOG4105D06	uba thif-type nad fad binding protein
GZI12_RS16545	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
GZI12_RS16555	ENOG4105C1J	atp-dependent rna helicase
GZI12_RS16560	ENOG4105CXG	d-lactate dehydrogenase
GZI12_RS16570	ENOG4105K5X	acetyltransferase
GZI12_RS16590	ENOG4105E5M	Multidrug resistance protein D
GZI12_RS16600	ENOG41067TZ	transcriptional regulator, MarR family
GZI12_RS16605	ENOG4105C94	Transporter
GZI12_RS16615	ENOG4105E0U	tyrosine-specific transport protein
GZI12_RS16620	ENOG4108ZYK	Acyl carrier protein phosphodiesterase
GZI12_RS16625	ENOG4105C1J	atp-dependent rna helicase
GZI12_RS16640	ENOG4105CHU	acetyl-coa acetyltransferase
GZI12_RS16650	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
GZI12_RS16655	ENOG4105QNF	Outer membrane lipoprotein
GZI12_RS16675	ENOG41080HT	Transcriptional regulator, arsr family
GZI12_RS16695	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
GZI12_RS16700	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
GZI12_RS16710	ENOG4105CGF	Aromatic amino acid aminotransferase
GZI12_RS16715	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
GZI12_RS16720	ENOG4108V1T	peptidylprolyl cis-trans isomerase
GZI12_RS16745	ENOG41090HJ	UPF0265 protein
GZI12_RS16755	ENOG4108YXG	UPF0502 protein
GZI12_RS16760	ENOG41082IR	Excinuclease ABC C subunit domain protein
GZI12_RS16770	ENOG4105BZU	Histidine kinase
GZI12_RS16780	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
GZI12_RS16785	ENOG4105EM2	membrane
GZI12_RS16790	ENOG41088T4	Helicase IV
GZI12_RS16805	ENOG4105BZU	Histidine kinase
GZI12_RS16815	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
GZI12_RS16835	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
GZI12_RS16840	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
GZI12_RS16845	ENOG4105E0C	molybdate abc transporter
GZI12_RS16865	ENOG4105BZU	Histidine kinase
GZI12_RS16880	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
GZI12_RS16885	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
GZI12_RS16895	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
GZI12_RS16925	ENOG4108ZJT	translation initiation factor, Sui1
GZI12_RS16940	ENOG4105CPF	Cell wall formation (By similarity)
GZI12_RS16950	ENOG4105CD5	CoA-binding domain protein
GZI12_RS16955	ENOG4105CWB	LysR family transcriptional Regulator
GZI12_RS16965	ENOG4105KNR	Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity)
GZI12_RS16975	ENOG4105KA0	thioesterase Superfamily protein
GZI12_RS16990	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
GZI12_RS17005	ENOG4105DU1	integral membrane protein, terc
GZI12_RS17010	ENOG4105CGH	5'-nucleotidase
GZI12_RS17020	ENOG4105DUM	transcriptional regulator, lysR family
GZI12_RS17025	ENOG4105TMB	Formate nitrite transporter
GZI12_RS17050	ENOG4105CEE	C4-dicarboxylate transporter
GZI12_RS17055	ENOG4105BZU	Histidine kinase
GZI12_RS17060	ENOG4105E7W	lamb ycsf family protein
GZI12_RS17070	ENOG4107R7A	Allophanate hydrolase subunit 2
GZI12_RS17080	ENOG4105CV6	ABC transporter, permease
GZI12_RS17085	ENOG4108I0Y	(ABC) transporter
GZI12_RS17095	ENOG4105RKW	reductase (By
GZI12_RS17100	ENOG4105BZU	Histidine kinase
GZI12_RS17125	ENOG4107UB3	HAD-superfamily hydrolase subfamily IA variant 3
GZI12_RS17140	ENOG4107RE1	Inosine-guanosine kinase
GZI12_RS17180	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
GZI12_RS17185	ENOG4105C2D	reductase
GZI12_RS17195	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
GZI12_RS17220	ENOG4105C84	Histidine ammonia-lyase
GZI12_RS17225	ENOG4107QJZ	Glycosyl transferase, family 2
GZI12_RS17280	ENOG4105M6F	mutator MutT protein
GZI12_RS17325	ENOG4107QQG	Dehydrogenase
GZI12_RS17415	ENOG4105DFG	type I secretion outer membrane protein
GZI12_RS17430	ENOG4105F2V	VRR-NUC domain-containing protein
GZI12_RS17435	ENOG4108M4U	conserved membrane protein
GZI12_RS17460	ENOG4107QVM	von Willebrand factor, type A
GZI12_RS17475	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
GZI12_RS17480	ENOG4108PPB	Seems to be required for the assembly of the photosystem I complex (By similarity)
GZI12_RS17485	ENOG4105ENH	Sulfatase
GZI12_RS17490	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
GZI12_RS17510	ENOG4105CKU	formyltetrahydrofolate synthetase
GZI12_RS17515	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
GZI12_RS17540	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
GZI12_RS17550	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
GZI12_RS17560	ENOG41081FY	multiple antibiotic resistance (MarC)-related
GZI12_RS17565	ENOG4105BZU	Histidine kinase
GZI12_RS17575	ENOG4105C1J	atp-dependent rna helicase
GZI12_RS17585	ENOG4105N1F	Hnh endonuclease
GZI12_RS17590	ENOG4105CEY	Amp-dependent synthetase and ligase
GZI12_RS17600	ENOG4105DR5	peptidase
GZI12_RS17605	ENOG4105CKI	cobalamin synthesis protein
GZI12_RS17610	ENOG4105CC0	LysR family Transcriptional regulator
GZI12_RS17615	ENOG4108ZZK	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity)
GZI12_RS17620	ENOG4107QR9	Iron-sulfur cluster binding protein
GZI12_RS17625	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
GZI12_RS17630	ENOG4105DAA	L-lactate
GZI12_RS17635	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
GZI12_RS17645	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
GZI12_RS17655	ENOG4108IPW	abc transporter atp-binding protein
GZI12_RS17660	ENOG4105CM4	permease protein
GZI12_RS17665	ENOG4105DHS	permease protein
GZI12_RS17680	ENOG4108JQ5	ABC transporter
GZI12_RS17685	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
GZI12_RS17690	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
GZI12_RS17755	ENOG4105D9N	nucleoside
GZI12_RS17780	ENOG4105CCF	Lysine exporter protein (Lyse ygga)
GZI12_RS17820	ENOG4105EQR	Transposase IS116 IS110 IS902
GZI12_RS17835	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
GZI12_RS17850	ENOG4105BZC	d-serine deaminase
GZI12_RS17870	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
GZI12_RS17875	ENOG4105CKI	cobalamin synthesis protein
GZI12_RS17890	ENOG4108MGY	Histidine kinase
GZI12_RS17895	ENOG4105EYH	Exonuclease
GZI12_RS17900	ENOG4107RFY	SbcCD D subunit
GZI12_RS17905	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
GZI12_RS17915	ENOG4105VXR	cytoplasmic protein
GZI12_RS17930	ENOG4105DY2	Paraquat-inducible protein b
GZI12_RS17935	ENOG4105F1S	paraquat-inducible protein a
GZI12_RS17950	ENOG4108NVR	Methyl-accepting chemotaxis
GZI12_RS17990	ENOG4108KTG	Membrane protein, drug metabolite transporter
GZI12_RS17995	ENOG4105EV2	VWA domain protein interacting with AAA ATPase
GZI12_RS18010	ENOG4105C5W	Aldolase
GZI12_RS18015	ENOG4106RE7	Cytochrome
GZI12_RS18020	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
GZI12_RS18030	ENOG4105NAE	bifunctional deaminase-reductase domain protein
GZI12_RS18065	ENOG4105KQ5	peptidylprolyl cis-trans isomerase
GZI12_RS18075	ENOG4106TD9	Diguanylate cyclase
GZI12_RS18090	ENOG4105EJQ	L-serine dehydratase
GZI12_RS18095	ENOG4105DUX	Transporter
GZI12_RS18120	ENOG4105PAD	Hydrolase
GZI12_RS18135	ENOG4105MIR	Phenylalanine 4-monooxygenase
GZI12_RS18145	ENOG4105EGI	Transcriptional regulator
GZI12_RS18165	ENOG4105CBG	Sulfatase
GZI12_RS18170	ENOG4105C4X	radical SAM domain protein
GZI12_RS18175	ENOG4105C1J	atp-dependent rna helicase
GZI12_RS18190	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
GZI12_RS18205	ENOG4105VRT	cytoplasmic protein
GZI12_RS18220	ENOG4105DZ1	carboxypeptidase
GZI12_RS18230	ENOG4105VEQ	Cold shock protein
GZI12_RS18250	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
GZI12_RS18255	ENOG4105C8P	)-transporter
GZI12_RS18260	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
GZI12_RS18265	ENOG4108JUA	Transcriptional regulator
GZI12_RS18280	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
GZI12_RS18285	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
GZI12_RS18295	ENOG4108SXK	Transporter Drug Metabolite Exporter family
GZI12_RS18300	ENOG4105VW4	glutaredoxin 3
GZI12_RS18325	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
GZI12_RS18330	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
GZI12_RS18340	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
GZI12_RS18350	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
GZI12_RS18355	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GZI12_RS18380	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
GZI12_RS18390	ENOG4105BZU	Histidine kinase
GZI12_RS18425	ENOG4105E5M	Multidrug resistance protein D
GZI12_RS18430	ENOG4105CNI	cell division protein FtsW
GZI12_RS18440	ENOG4108UYE	Lactoylglutathione lyase
GZI12_RS18445	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
GZI12_RS18450	ENOG4108V1U	phospholipid-binding protein
GZI12_RS18455	ENOG4108ZX5	transcriptional regulator
GZI12_RS18475	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
GZI12_RS18515	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
GZI12_RS18535	ENOG4105BZU	Histidine kinase
GZI12_RS18560	ENOG4105NBK	UPF0345 protein
GZI12_RS18565	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
GZI12_RS18575	ENOG4105D64	Mechanosensitive ion channel
GZI12_RS18590	ENOG4108S58	Phenazine biosynthesis protein PhzF
GZI12_RS18600	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
GZI12_RS18605	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
GZI12_RS18610	ENOG41082NX	50s ribosomal protein l35
GZI12_RS18615	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
GZI12_RS18620	ENOG4105C22	threonyL-tRNA synthetase
GZI12_RS18625	ENOG4108UHU	Aldolase
GZI12_RS18635	ENOG4105CHR	reductase
GZI12_RS18640	ENOG4105J4Q	Transcriptional regulator
GZI12_RS18665	ENOG4105DAS	pts system
GZI12_RS18670	ENOG4105F3R	pts system mannose fructose sorbose family iid
GZI12_RS18675	ENOG4105ETZ	PTS System
GZI12_RS18695	ENOG4106AM8	polysaccharide lyase family 8
GZI12_RS18730	ENOG4105FCK	Membrane
GZI12_RS18740	ENOG4105CC0	LysR family Transcriptional regulator
GZI12_RS18760	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
GZI12_RS18770	ENOG4107FB0	transcriptional regulator DeoR family
GZI12_RS18780	ENOG4108RVA	ribokinase
GZI12_RS18785	ENOG4105EDR	glucose galactose transporter
GZI12_RS18820	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
GZI12_RS18830	ENOG4108MCI	Transcriptional regulator, ARAC family
GZI12_RS18840	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
GZI12_RS18845	ENOG410642W	LysR family Transcriptional regulator
GZI12_RS18865	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GZI12_RS18870	ENOG4105C5Y	PTS System
GZI12_RS18880	ENOG4105D3G	Pseudouridine synthase
GZI12_RS18885	ENOG41061ZR	Transcriptional regulator
GZI12_RS18890	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
GZI12_RS18895	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
GZI12_RS18900	ENOG4107T9C	Alpha amylase catalytic region
GZI12_RS18905	ENOG4108N3W	hemolysin secretion protein
GZI12_RS18910	ENOG4105BZU	Histidine kinase
GZI12_RS18925	ENOG4105D56	permease protein
GZI12_RS18935	ENOG4108KDD	Involved in the transport of maltose and maltodextrins (By similarity)
GZI12_RS18940	ENOG4107W52	maltose operon periplasmic protein
GZI12_RS18945	ENOG4105Q9Y	Universal stress protein
GZI12_RS18960	ENOG4105V0I	UPF0267 protein
GZI12_RS18970	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
GZI12_RS18975	ENOG4105W8I	Transcriptional regulator
GZI12_RS18980	ENOG4107UCJ	Catalyzes the synthesis of activated sulfate (By similarity)
GZI12_RS18990	ENOG4108Z4X	TRANSCRIPTIONal
GZI12_RS19045	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
GZI12_RS19050	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
GZI12_RS19055	ENOG4107RGH	Aldehyde dehydrogenase
GZI12_RS19060	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
GZI12_RS19065	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
GZI12_RS19070	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
GZI12_RS19075	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
GZI12_RS19085	ENOG4105DRS	transport system, permease
GZI12_RS19100	ENOG4107KJX	Transcriptional regulator
GZI12_RS19105	ENOG4107T40	Inherit from COG: Glycosyltransferase 36
GZI12_RS19135	ENOG4105HEI	LysR family (Transcriptional regulator
GZI12_RS19165	ENOG4105EKT	)-iron permease
GZI12_RS19175	ENOG4105DBE	peroxidase
GZI12_RS19180	ENOG4105F0N	pyrophosphate phospho-hydrolase
GZI12_RS19190	ENOG4105DJ2	Major Facilitator Superfamily
GZI12_RS19195	ENOG4105R1U	AraC Family Transcriptional Regulator
GZI12_RS19225	ENOG4105W3H	MtN3 and saliva related transmembrane protein
GZI12_RS19230	ENOG4105F8D	glycoside hydrolase family 4
GZI12_RS19235	ENOG4105CI1	PTS System
GZI12_RS19240	ENOG4105FDP	GntR family transcriptional regulator
GZI12_RS19250	ENOG4105CGH	5'-nucleotidase
GZI12_RS19280	ENOG4108NIW	Leucine export protein LeuE
GZI12_RS19305	ENOG4105D6U	Sodium Glutamate Symporter
GZI12_RS19320	ENOG4105CI1	PTS System
GZI12_RS19340	ENOG4105HEI	LysR family (Transcriptional regulator
GZI12_RS19350	ENOG4105CK2	sodium dicarboxylate symporter
GZI12_RS19355	ENOG4105CEP	NADH dehydrogenase
GZI12_RS19375	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
GZI12_RS19400	ENOG4105C5Y	PTS System
GZI12_RS19405	ENOG4105EJC	lysr family transcriptional regulator
GZI12_RS19410	ENOG4105HEI	LysR family (Transcriptional regulator
GZI12_RS19420	ENOG4105CXN	decarboxylase
GZI12_RS19425	ENOG4105D5Q	Arginine ornithine antiporter
GZI12_RS19445	ENOG4108HQS	Glycine betaine
GZI12_RS19450	ENOG4108IJ7	Glycine betaine
GZI12_RS19460	ENOG4105JGI	Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes (By similarity)
GZI12_RS19485	ENOG4105C37	(CBS) domain
GZI12_RS19500	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
GZI12_RS19510	ENOG4107FB0	transcriptional regulator DeoR family
GZI12_RS19520	ENOG4105CMG	Carbohydrate kinase
GZI12_RS19525	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
GZI12_RS19530	ENOG4108FN7	Aldo keto reductase
GZI12_RS19535	ENOG4105EDR	glucose galactose transporter
GZI12_RS19560	ENOG4105BZG	amino acid carrier protein
GZI12_RS19565	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
GZI12_RS19580	ENOG4105E5D	amino acid
GZI12_RS19605	ENOG4105EIP	mannose-6-phosphate isomerase
GZI12_RS19610	ENOG4105C8I	hydrolase, family 38
GZI12_RS19615	ENOG4105DM4	PTS System
GZI12_RS19620	ENOG4105FDP	GntR family transcriptional regulator
GZI12_RS19640	ENOG4107QKS	N-acylglucosamine 2-epimerase
GZI12_RS19645	ENOG4105CI1	PTS System
GZI12_RS19650	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
GZI12_RS19655	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
GZI12_RS19670	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
GZI12_RS19675	ENOG4105F1A	Pyruvate formate-lyase
GZI12_RS19690	ENOG4105HDD	phospholipase
GZI12_RS19705	ENOG4105G2Y	Transcriptional regulator
GZI12_RS19715	ENOG4105ETX	regulatoR
GZI12_RS19730	ENOG4105ETX	regulatoR
GZI12_RS19755	ENOG41080VW	acetyltransferase
GZI12_RS19760	ENOG4105YCT	UPF0386 protein
GZI12_RS19765	ENOG4105CR8	Transcriptional regulator
GZI12_RS19810	ENOG4105C2C	drug resistance transporter, Bcr CflA
GZI12_RS19815	ENOG4105R1U	AraC Family Transcriptional Regulator
GZI12_RS19830	ENOG4105CJQ	hydrolase, family 31
GZI12_RS19835	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
GZI12_RS19845	ENOG41080UQ	Transcriptional regulator
GZI12_RS19850	ENOG4108MGF	sugar kinase
GZI12_RS19860	ENOG4105VYW	UPF0251 protein
GZI12_RS19875	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
GZI12_RS19890	ENOG4105DUM	transcriptional regulator, lysR family
GZI12_RS19925	ENOG4105EGS	Mechanosensitive ion channel
GZI12_RS19945	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
GZI12_RS19950	ENOG4106RMF	ParB family
GZI12_RS20005	ENOG4108VAU	general secretion pathway protein G
GZI12_RS20075	ENOG4108Z03	MAF-like protein
GZI12_RS20080	ENOG4108Z03	MAF-like protein
GZI12_RS20140	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)