locus-tag	class	description
GPY16_RS00010	ENOG4108RR8	protoporphyrinogen oxidase
GPY16_RS00015	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
GPY16_RS00020	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
GPY16_RS00025	ENOG4108DP9	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain
GPY16_RS00035	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
GPY16_RS00050	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
GPY16_RS00065	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
GPY16_RS00080	ENOG4105JKW	Valine--pyruvate aminotransferase
GPY16_RS00085	ENOG4105BZU	Histidine kinase
GPY16_RS00090	ENOG4108ZNX	Heat shock protein
GPY16_RS00095	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GPY16_RS00100	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
GPY16_RS00105	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
GPY16_RS00110	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
GPY16_RS00115	ENOG4105EAB	amino acid AbC transporter
GPY16_RS00120	ENOG4105E5Q	amino acid AbC transporter
GPY16_RS00125	ENOG4105CDA	abc transporter atp-binding protein
GPY16_RS00130	ENOG4105VG0	50S ribosomal protein l34
GPY16_RS00135	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
GPY16_RS00140	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
GPY16_RS00150	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
GPY16_RS00155	ENOG4105QTB	Flavodoxin
GPY16_RS00165	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
GPY16_RS00170	ENOG4107QJE	Chromosome Partitioning Protein
GPY16_RS00175	ENOG4105FA0	parb-like partition protein
GPY16_RS00180	ENOG410684E	atp synthase
GPY16_RS00185	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
GPY16_RS00190	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
GPY16_RS00195	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
GPY16_RS00200	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
GPY16_RS00205	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
GPY16_RS00210	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
GPY16_RS00215	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
GPY16_RS00220	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
GPY16_RS00225	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
GPY16_RS00230	ENOG4105EAD	ABC transporter
GPY16_RS00235	ENOG4105F87	Dehydratase
GPY16_RS00240	ENOG4105CZQ	inner membrane transport protein YdhC
GPY16_RS00245	ENOG4105F52	Transcriptional regulator
GPY16_RS00250	ENOG4105C7B	Threonine dehydratase
GPY16_RS00260	ENOG4105CM2	brancheD-chain amino acid aminotransferase
GPY16_RS00265	ENOG4105P3Y	Acetolactate synthase 2 regulatory subunit
GPY16_RS00275	ENOG4105C0P	Mg chelatase subunit ChlI
GPY16_RS00290	ENOG4105M03	Domain of unknown function (DUF955)
GPY16_RS00305	ENOG4106HNH	Acyl-transferase
GPY16_RS00310	ENOG4108Z33	Thiol disulfide Interchange Protein
GPY16_RS00315	ENOG4105E27	serine threonine protein kinase
GPY16_RS00325	ENOG4105PC1	Conserved Protein
GPY16_RS00330	ENOG4108N23	SpoOM-related protein
GPY16_RS00335	ENOG4108UT2	hemolysin iii
GPY16_RS00340	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
GPY16_RS00345	ENOG4105C1A	potassium transporter peripheral membrane
GPY16_RS00370	ENOG4105C79	DNA protecting protein DprA
GPY16_RS00375	ENOG4108RPN	Protein smg homolog
GPY16_RS00380	ENOG4108WI1	Dna topoisomerase
GPY16_RS00385	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
GPY16_RS00390	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
GPY16_RS00395	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
GPY16_RS00410	ENOG4105SG3	Protein of unknown function (DUF1488)
GPY16_RS00415	ENOG4108Z0R	Transferase
GPY16_RS00450	ENOG4105EMY	transcriptional regulator
GPY16_RS00455	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
GPY16_RS00460	ENOG4105W0Z	cytoplasmic protein
GPY16_RS00465	ENOG4105BZS	acriflavin resistance protein
GPY16_RS00470	ENOG410624X	efflux transporter, rnd family, mfp subunit
GPY16_RS00475	ENOG4105Y7M	Transcriptional regulator, TetR family
GPY16_RS00480	ENOG4105C4R	Atp-dependent dna helicase
GPY16_RS00485	ENOG4105MPD	Cytochrome
GPY16_RS00515	ENOG4108JQ6	ABC transporter
GPY16_RS00520	ENOG4107QSI	ABC, transporter
GPY16_RS00525	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
GPY16_RS00530	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
GPY16_RS00565	ENOG4108DT4	serine threonine protein kinase
GPY16_RS00575	ENOG4108VYJ	response regulator receiver protein
GPY16_RS00580	ENOG4105DIQ	Transcriptional regulator
GPY16_RS00590	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
GPY16_RS00595	ENOG4105C6Z	Gluconate
GPY16_RS00600	ENOG4108UHU	Aldolase
GPY16_RS00615	ENOG4105DC8	reductase
GPY16_RS00620	ENOG4105D6S	protein involved in catabolism of external DNA
GPY16_RS00625	ENOG4105DGW	oligopeptidase A
GPY16_RS00630	ENOG4108VVK	transcriptional Regulator, AsnC
GPY16_RS00635	ENOG4105BZU	Histidine kinase
GPY16_RS00650	ENOG4105EMK	carboxylate amino acid amine transporter
GPY16_RS00655	ENOG4108M6U	Universal stress protein A
GPY16_RS00660	ENOG41090A1	ferritin
GPY16_RS00665	ENOG4108V6B	universal stress protein B
GPY16_RS00670	ENOG4105CBX	hi0933 family
GPY16_RS00680	ENOG4105ECF	c-methyltransferase
GPY16_RS00685	ENOG41076E6	Uroporphyrinogen-III Synthase
GPY16_RS00695	ENOG4107T0K	Adenylate cyclase
GPY16_RS00700	ENOG4105XQ6	frataxin-like protein
GPY16_RS00710	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
GPY16_RS00715	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
GPY16_RS00725	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
GPY16_RS00730	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
GPY16_RS00735	ENOG4105BZU	Histidine kinase
GPY16_RS00740	ENOG4106IUH	DTW domain containing protein
GPY16_RS00755	ENOG4105DQF	Hydrolase
GPY16_RS00760	ENOG4108EUD	Lysophospholipase
GPY16_RS00765	ENOG410829K	Lysine exporter protein (Lyse ygga)
GPY16_RS00770	ENOG4105D58	Diguanylate phosphodiesterase
GPY16_RS00775	ENOG41082YX	Transcriptional regulator, arsr family
GPY16_RS00780	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
GPY16_RS00820	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
GPY16_RS00830	ENOG4106H78	methyltransferase
GPY16_RS00835	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
GPY16_RS00840	ENOG4105CAK	Cell division ATP-binding protein ftsE
GPY16_RS00845	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
GPY16_RS00850	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GPY16_RS00855	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
GPY16_RS00860	ENOG4105EBW	Rhomboid-type serine protease that catalyzes intramembrane proteolysis (By similarity)
GPY16_RS00865	ENOG4105X6C	Flagellar basal body-associated protein FliL
GPY16_RS00875	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
GPY16_RS00885	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
GPY16_RS00895	ENOG4105DX1	Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity)
GPY16_RS00920	ENOG4105JXR	Protein of unknown function (DUF3296)
GPY16_RS00935	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
GPY16_RS00945	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
GPY16_RS00950	ENOG410624X	efflux transporter, rnd family, mfp subunit
GPY16_RS00990	ENOG4108YGG	dna repair protein
GPY16_RS01010	ENOG4107QMH	DNA methylase
GPY16_RS01030	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
GPY16_RS01045	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
GPY16_RS01120	ENOG4105JIM	Phosphatidylserine synthase
GPY16_RS01135	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
GPY16_RS01140	ENOG4105CS9	pantothenic acid kinase
GPY16_RS01165	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
GPY16_RS01170	ENOG4105PM1	preprotein translocase subunit SecE
GPY16_RS01175	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
GPY16_RS01180	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
GPY16_RS01185	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
GPY16_RS01190	ENOG4108VZM	50s ribosomal protein L10
GPY16_RS01195	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
GPY16_RS01200	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
GPY16_RS01205	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
GPY16_RS01210	ENOG4108ZVW	Anti-RNA polymerase sigma 70 factor
GPY16_RS01215	ENOG4105E09	nadh pyrophosphatase
GPY16_RS01230	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
GPY16_RS01235	ENOG4108RG0	uracil-dna glycosylase
GPY16_RS01240	ENOG4105C5I	Dehydrogenase
GPY16_RS01245	ENOG4105R2J	Conserved Protein
GPY16_RS01265	ENOG4105C12	Phosphoribosylglycinamide synthetase
GPY16_RS01270	ENOG4105DC1	bifunctional purine biosynthesis protein purh
GPY16_RS01275	ENOG4105W1Y	Transcriptional regulator
GPY16_RS01280	ENOG4105C8Q	Methyl-accepting chemotaxis
GPY16_RS01290	ENOG4107R3N	Filamentation induced by cAMP protein fic
GPY16_RS01305	ENOG4105DZR	Type I site-specific deoxyribonuclease
GPY16_RS01315	ENOG4105CVR	type I restriction-modification system
GPY16_RS01335	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
GPY16_RS01385	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
GPY16_RS01390	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
GPY16_RS01400	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
GPY16_RS01405	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
GPY16_RS01410	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
GPY16_RS01430	ENOG4105D8G	Major Facilitator superfamily
GPY16_RS01435	ENOG4105BZU	Histidine kinase
GPY16_RS01450	ENOG4107QN1	sodium solute
GPY16_RS01460	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
GPY16_RS01475	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
GPY16_RS01480	ENOG4108IJ0	Aspartate ammonia-lyase
GPY16_RS01490	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
GPY16_RS01495	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
GPY16_RS01500	ENOG4105E0F	Histidine kinase
GPY16_RS01505	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
GPY16_RS01510	ENOG4108SPG	Periplasmic Protein
GPY16_RS01515	ENOG41076HS	cation diffusion facilitator family transporter
GPY16_RS01520	ENOG4105CTQ	phosphohexokinase
GPY16_RS01525	ENOG4107QI1	Mate efflux family protein
GPY16_RS01530	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
GPY16_RS01535	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
GPY16_RS01545	ENOG4105KT7	mgtC SapB transporter
GPY16_RS01550	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
GPY16_RS01555	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
GPY16_RS01575	ENOG4108WJH	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
GPY16_RS01590	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
GPY16_RS01600	ENOG41062JF	Transcriptional regulator
GPY16_RS01610	ENOG41063SB	peptidase
GPY16_RS01615	ENOG4105D7W	serine acetyltransferase
GPY16_RS01620	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
GPY16_RS01625	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
GPY16_RS01630	ENOG4107YZP	Rhodanese domain protein
GPY16_RS01650	ENOG4105C8P	)-transporter
GPY16_RS01655	ENOG4105DJ4	phosphatidylserine decarboxylase
GPY16_RS01660	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
GPY16_RS01665	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
GPY16_RS01725	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
GPY16_RS01730	ENOG4105K8N	protein family UPF0079, ATPase
GPY16_RS01735	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
GPY16_RS01745	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
GPY16_RS01750	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
GPY16_RS01755	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
GPY16_RS01760	ENOG4107QJR	hflk protein
GPY16_RS01765	ENOG4105EPW	hflc protein
GPY16_RS01780	ENOG4108UV7	flagellar protein motX
GPY16_RS01785	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
GPY16_RS01790	ENOG4105KPV	Transcriptional regulator
GPY16_RS01795	ENOG4107SYB	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
GPY16_RS01800	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
GPY16_RS01805	ENOG4105C2N	RNA methyltransferase TrmH family group 3
GPY16_RS01810	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
GPY16_RS01815	ENOG4105C31	Tryptophanyl-tRNA synthetase
GPY16_RS01845	ENOG4105C26	Dehydrogenase
GPY16_RS01855	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
GPY16_RS01860	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
GPY16_RS01865	ENOG4105YP7	UPF0270 protein
GPY16_RS01870	ENOG4105DNZ	Alpha Beta Hydrolase
GPY16_RS01880	ENOG4105C5H	ABC transporter
GPY16_RS01885	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
GPY16_RS01900	ENOG4108YZY	peptidylprolyl cis-trans isomerase
GPY16_RS01905	ENOG4105D44	asparaginase
GPY16_RS01910	ENOG41069P5	Protein slyX homolog
GPY16_RS01920	ENOG4108V1T	peptidylprolyl cis-trans isomerase
GPY16_RS01925	ENOG4105WWK	YheO domain protein
GPY16_RS01935	ENOG4108ZKU	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
GPY16_RS01945	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
GPY16_RS01950	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
GPY16_RS01960	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
GPY16_RS01965	ENOG4105W53	bacterioferritin-associated ferredoxin
GPY16_RS01970	ENOG4108UQY	Iron-storage protein
GPY16_RS01975	ENOG4105CMR	udp-glucose 4-epimerase
GPY16_RS01980	ENOG4105CP7	Triose-phosphate isomerase
GPY16_RS02005	ENOG4105CBT	Fructose-1,6-bisphosphatase
GPY16_RS02010	ENOG41065UX	Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA (By similarity)
GPY16_RS02015	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
GPY16_RS02020	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
GPY16_RS02025	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
GPY16_RS02030	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
GPY16_RS02040	ENOG4105ETE	Transcriptional regulator (LacI family
GPY16_RS02045	ENOG4105C25	Primosomal protein n'
GPY16_RS02050	ENOG4105VFB	Binds the 23S rRNA (By similarity)
GPY16_RS02055	ENOG4105C6K	Malic enzyme
GPY16_RS02060	ENOG4105GGQ	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity)
GPY16_RS02065	ENOG4105C28	cystathionine
GPY16_RS02070	ENOG4105CFH	Aspartokinase
GPY16_RS02075	ENOG4105SYT	Methylenetetrahydrofolate reductase
GPY16_RS02100	ENOG4105CAS	nag kinase
GPY16_RS02105	ENOG4105CDH	Citrulline--aspartate ligase
GPY16_RS02110	ENOG4105CH7	arginosuccinase
GPY16_RS02120	ENOG4105C5Q	Transcriptional regulator
GPY16_RS02125	ENOG4108JQC	penicillin-binding protein 1A
GPY16_RS02150	ENOG4105E4G	Type IV pilus
GPY16_RS02155	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
GPY16_RS02160	ENOG4105D49	3-dehydroquinate synthase
GPY16_RS02170	ENOG4105DFE	Dna adenine methylase
GPY16_RS02175	ENOG4105DJV	ribulose-phosphate 3-epimerase
GPY16_RS02180	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
GPY16_RS02185	ENOG4108VDV	Binds single-stranded DNA at the primosome assembly site (PAS) (By similarity)
GPY16_RS02190	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
GPY16_RS02195	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
GPY16_RS02205	ENOG4105CDU	Replicative dna helicase
GPY16_RS02220	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
GPY16_RS02225	ENOG4107QP8	phosphohexose isomerase
GPY16_RS02235	ENOG4105MYN	Zinc uptake regulation protein
GPY16_RS02240	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
GPY16_RS02260	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
GPY16_RS02270	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
GPY16_RS02350	ENOG4105BZU	Histidine kinase
GPY16_RS02355	ENOG4105EEQ	Na H antiporter
GPY16_RS02365	ENOG4105CFH	Aspartokinase
GPY16_RS02370	ENOG4105C5R	Aminotransferase
GPY16_RS02380	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
GPY16_RS02385	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
GPY16_RS02390	ENOG41086KC	Transcriptional regulator
GPY16_RS02395	ENOG4108UUM	single-stranded DNA-binding protein
GPY16_RS02400	ENOG41062P1	Diguanylate cyclase phosphodiesterase
GPY16_RS02420	ENOG4105E4G	Type IV pilus
GPY16_RS02435	ENOG4107QHF	type ii secretion system protein e
GPY16_RS02440	ENOG4105D7Q	type ii secretion system
GPY16_RS02450	ENOG4105X0D	Fimbrial protein
GPY16_RS02485	ENOG4105DFF	Rod shape-determining protein mreb
GPY16_RS02490	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
GPY16_RS02495	ENOG4105VQ7	Rod shape-determining protein MreD
GPY16_RS02500	ENOG4108Z03	MAF-like protein
GPY16_RS02505	ENOG4105C03	ribonuclease
GPY16_RS02510	ENOG4105QD6	exported protein
GPY16_RS02520	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
GPY16_RS02525	ENOG4108IAB	Phoh family
GPY16_RS02535	ENOG4105D3G	Pseudouridine synthase
GPY16_RS02540	ENOG4105C5I	Dehydrogenase
GPY16_RS02545	ENOG4105KME	endoribonuclease L-psp
GPY16_RS02550	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
GPY16_RS02555	ENOG4105CXT	aspartate transcarbamylase
GPY16_RS02560	ENOG4105DBV	ornithine carbamoyltransferase
GPY16_RS02565	ENOG4105CEU	Arginine dihydrolase
GPY16_RS02580	ENOG4108MJ3	acetyltransferase
GPY16_RS02590	ENOG4108M3P	Membrane
GPY16_RS02600	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
GPY16_RS02605	ENOG4105MYG	DNA polymerase iii, chi subunit
GPY16_RS02610	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
GPY16_RS02615	ENOG4108M8S	permease YjgP YjgQ family protein
GPY16_RS02620	ENOG4108K5H	permease YjgP YjgQ family protein
GPY16_RS02640	ENOG4105VZJ	PTS System
GPY16_RS02650	ENOG4105VCP	PTS System
GPY16_RS02655	ENOG4105F8D	glycoside hydrolase family 4
GPY16_RS02665	ENOG4105DDV	Transcriptional regulator (LacI family
GPY16_RS02760	ENOG4105C8Q	Methyl-accepting chemotaxis
GPY16_RS02780	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
GPY16_RS02785	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
GPY16_RS02790	ENOG4105CEN	a g-specific adenine glycosylase
GPY16_RS02795	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
GPY16_RS02800	ENOG4105CSV	Glutaminase
GPY16_RS02805	ENOG4105CSA	Coproporphyrinogen iii oxidase
GPY16_RS02810	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
GPY16_RS02820	ENOG4105VZ9	UPF0235 protein
GPY16_RS02825	ENOG4108VIA	integral membrane protein
GPY16_RS02830	ENOG4105II7	pyrroline-5-carboxylate reductase
GPY16_RS02835	ENOG4105DFA	alanine racemase domain protein
GPY16_RS02840	ENOG4105CZX	twitching motility protein
GPY16_RS02845	ENOG4105CZX	twitching motility protein
GPY16_RS02850	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
GPY16_RS02855	ENOG4108UJU	UPF0301 protein
GPY16_RS02860	ENOG4105D7Z	glutathione synthase
GPY16_RS02865	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
GPY16_RS02875	ENOG4105RWS	endonuclease I
GPY16_RS02880	ENOG4105GPY	SprT protein
GPY16_RS02890	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
GPY16_RS02910	ENOG4105BZA	Phosphoglycerate kinase
GPY16_RS02915	ENOG4105D2N	Aldolase
GPY16_RS02920	ENOG4105D64	Mechanosensitive ion channel
GPY16_RS02925	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
GPY16_RS02930	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
GPY16_RS02940	ENOG4108JQ1	Dehydrogenase
GPY16_RS02945	ENOG4105E66	phosphoriboisomerase A
GPY16_RS02950	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
GPY16_RS02960	ENOG4107YUN	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
GPY16_RS02970	ENOG4105D0A	hydroxylase
GPY16_RS02975	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
GPY16_RS02995	ENOG4105Y75	tpr repeat protein
GPY16_RS03005	ENOG4108IYU	L-aspartate oxidase
GPY16_RS03010	ENOG4105EMN	RNA polymerase sigma factor
GPY16_RS03025	ENOG4105WMJ	Positive regulator of sigma E, RseC MucC
GPY16_RS03030	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
GPY16_RS03035	ENOG4105C3F	Signal peptidase i
GPY16_RS03040	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
GPY16_RS03045	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
GPY16_RS03055	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
GPY16_RS03075	ENOG4105BZU	Histidine kinase
GPY16_RS03080	ENOG4105BZU	Histidine kinase
GPY16_RS03090	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
GPY16_RS03095	ENOG4105DXN	mazG family
GPY16_RS03100	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
GPY16_RS03105	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
GPY16_RS03110	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
GPY16_RS03115	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
GPY16_RS03130	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
GPY16_RS03135	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
GPY16_RS03140	ENOG4108K5P	(LipO)protein
GPY16_RS03145	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GPY16_RS03155	ENOG4107TH8	cina domain protein
GPY16_RS03160	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
GPY16_RS03165	ENOG4105Y3E	Modulates RecA activity (By similarity)
GPY16_RS03175	ENOG4105CFH	Aspartokinase
GPY16_RS03180	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
GPY16_RS03230	ENOG4107QSA	Oxaloacetate decarboxylase
GPY16_RS03235	ENOG4105D9Q	decarboxylase (Beta subunit)
GPY16_RS03245	ENOG4105W39	Membrane
GPY16_RS03255	ENOG4105D9M	gamma-glutamylcysteine synthetase
GPY16_RS03265	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
GPY16_RS03270	ENOG4108JU6	CBS domain protein
GPY16_RS03275	ENOG4106KVJ	cytochrome C assembly protein
GPY16_RS03280	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GPY16_RS03285	ENOG4105K5M	30s ribosomal protein S16
GPY16_RS03290	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
GPY16_RS03295	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
GPY16_RS03300	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
GPY16_RS03310	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
GPY16_RS03320	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
GPY16_RS03325	ENOG4105D7Q	type ii secretion system
GPY16_RS03330	ENOG4107QHF	type ii secretion system protein e
GPY16_RS03335	ENOG4105X0D	Fimbrial protein
GPY16_RS03340	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
GPY16_RS03345	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
GPY16_RS03350	ENOG41073TP	transcriptional regulator
GPY16_RS03355	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
GPY16_RS03360	ENOG4107QSN	dihydrolipoamide acetyltransferase
GPY16_RS03365	ENOG4107QN2	dihydrolipoyl dehydrogenase
GPY16_RS03370	ENOG410630P	Transcriptional regulator
GPY16_RS03375	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
GPY16_RS03380	ENOG41077A9	carbonic anhydrase
GPY16_RS03385	ENOG4105CHH	sulfate transporter
GPY16_RS03390	ENOG4105DA5	(ABC) transporter
GPY16_RS03395	ENOG4105E3A	(ABC) transporter
GPY16_RS03400	ENOG4107R03	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
GPY16_RS03405	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
GPY16_RS03410	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GPY16_RS03415	ENOG4105DJ0	Poly(A) Polymerase
GPY16_RS03420	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
GPY16_RS03425	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GPY16_RS03435	ENOG4105CQ7	ATP-dependent helicase
GPY16_RS03440	ENOG4105BZ4	penicillin-binding protein
GPY16_RS03445	ENOG4105D78	K07001 NTE family protein
GPY16_RS03450	ENOG4107QIJ	Aconitate hydratase 2
GPY16_RS03455	ENOG4105BZW	Glycerate kinase
GPY16_RS03460	ENOG4107QQ0	gntp family
GPY16_RS03465	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
GPY16_RS03470	ENOG4105XTV	UPF0231 protein
GPY16_RS03475	ENOG4108YZA	Nitrogen regulatory protein pii
GPY16_RS03495	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
GPY16_RS03500	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
GPY16_RS03510	ENOG4105E2D	ec 3.2.1.52
GPY16_RS03515	ENOG4105RD7	BadF BadG BcrA BcrD
GPY16_RS03525	ENOG4108JQ7	(ABC) transporter
GPY16_RS03530	ENOG4105C3U	ABC transporter
GPY16_RS03535	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
GPY16_RS03545	ENOG4107QRA	Extracellular solute-binding protein, family 5
GPY16_RS03550	ENOG4105BZU	Histidine kinase
GPY16_RS03555	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
GPY16_RS03560	ENOG4105F4G	Membrane
GPY16_RS03565	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
GPY16_RS03570	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
GPY16_RS03585	ENOG4105DR5	peptidase
GPY16_RS03590	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
GPY16_RS03595	ENOG4105WD1	Membrane
GPY16_RS03600	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
GPY16_RS03605	ENOG4105FCK	Membrane
GPY16_RS03610	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
GPY16_RS03615	ENOG4105HBR	Rna-binding protein
GPY16_RS03620	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
GPY16_RS03625	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
GPY16_RS03630	ENOG4105EEI	dihydropteroate synthase
GPY16_RS03635	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
GPY16_RS03655	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
GPY16_RS03660	ENOG4105CHV	Transcription elongation factor NusA
GPY16_RS03665	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
GPY16_RS03670	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
GPY16_RS03675	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
GPY16_RS03680	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
GPY16_RS03695	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
GPY16_RS03700	ENOG4105RT1	May be involved in cell division (By similarity)
GPY16_RS03710	ENOG4105C3S	Mate efflux family protein
GPY16_RS03715	ENOG4106RZ4	Peptidase U32
GPY16_RS03720	ENOG4105CFP	Peptidase U32
GPY16_RS03725	ENOG4105BZU	Histidine kinase
GPY16_RS03730	ENOG4105XPQ	lipid carrier protein
GPY16_RS03735	ENOG4108YYD	acetyltransferase
GPY16_RS03745	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
GPY16_RS03750	ENOG4105BZU	Histidine kinase
GPY16_RS03755	ENOG4105BZU	Histidine kinase
GPY16_RS03760	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
GPY16_RS03770	ENOG4105EYA	deoxyribonuclease
GPY16_RS03775	ENOG4105D9N	nucleoside
GPY16_RS03785	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
GPY16_RS03790	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
GPY16_RS03795	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
GPY16_RS03805	ENOG4105EAC	phosphoserine phosphatase
GPY16_RS03820	ENOG4105BZU	Histidine kinase
GPY16_RS03840	ENOG4108IQE	Amp-dependent synthetase and ligase
GPY16_RS03925	ENOG4105FGV	Chromate
GPY16_RS03930	ENOG41064T2	transcriptional regulator, lysR family
GPY16_RS03940	ENOG4107WCA	isomerase
GPY16_RS03945	ENOG4105E5D	amino acid
GPY16_RS03950	ENOG4105E5D	amino acid
GPY16_RS03955	ENOG4105FK9	beta-D-galactosidase beta subunit
GPY16_RS03960	ENOG4105CNT	hydrolase family 2
GPY16_RS03970	ENOG4105CQ4	Transcriptional regulator
GPY16_RS03975	ENOG4105CMR	udp-glucose 4-epimerase
GPY16_RS03980	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
GPY16_RS03985	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
GPY16_RS03990	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
GPY16_RS03995	ENOG4105C8Q	Methyl-accepting chemotaxis
GPY16_RS04005	ENOG4108Y51	tRNA-binding protein
GPY16_RS04020	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
GPY16_RS04035	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
GPY16_RS04040	ENOG4105E98	transcriptional regulator DeoR family
GPY16_RS04045	ENOG4108HMR	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
GPY16_RS04050	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
GPY16_RS04055	ENOG4105EJ3	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity)
GPY16_RS04060	ENOG4105X2V	dna damage-inducible protein
GPY16_RS04065	ENOG4105EVZ	LysR family transcriptional regulator
GPY16_RS04075	ENOG4105E68	Sulfatase
GPY16_RS04080	ENOG4105DSY	exodeoxyribonuclease V, gamma
GPY16_RS04085	ENOG4107QKA	exodeoxyribonuclease V beta
GPY16_RS04090	ENOG4107QYX	exodeoxyribonuclease v alpha
GPY16_RS04100	ENOG4107QZM	n-acetylglutamate synthase
GPY16_RS04110	ENOG4105CA3	membrane-bound lytic murein transglycosylase
GPY16_RS04115	ENOG4105CUZ	uba thif-type nad fad binding protein
GPY16_RS04120	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
GPY16_RS04125	ENOG4105C9B	Cysteine desulfurase
GPY16_RS04130	ENOG4107S0N	DJ-1 family
GPY16_RS04135	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
GPY16_RS04150	ENOG4105K6V	RNA polymerase
GPY16_RS04160	ENOG4105EYM	Major Facilitator superfamily
GPY16_RS04165	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
GPY16_RS04175	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
GPY16_RS04180	ENOG4105M85	Bola protein
GPY16_RS04185	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
GPY16_RS04190	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
GPY16_RS04195	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
GPY16_RS04200	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
GPY16_RS04205	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
GPY16_RS04210	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
GPY16_RS04215	ENOG4105CJ2	(LipO)protein
GPY16_RS04225	ENOG4105BZU	Histidine kinase
GPY16_RS04230	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
GPY16_RS04235	ENOG4105C9U	ATP-dependent DNA helicase RecQ
GPY16_RS04250	ENOG4105C8J	)-transporter
GPY16_RS04260	ENOG4105W1I	UPF0253 protein
GPY16_RS04270	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
GPY16_RS04275	ENOG4108R96	Methyltransferase, YaeB family
GPY16_RS04290	ENOG4105CFC	Transporter
GPY16_RS04325	ENOG4105WP7	tRNA pseudouridine synthase C
GPY16_RS04330	ENOG4105DR9	pseudouridine synthase
GPY16_RS04335	ENOG4108T8E	UPF0325 protein
GPY16_RS04345	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
GPY16_RS04350	ENOG4105CE9	30S ribosomal protein S2
GPY16_RS04355	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
GPY16_RS04360	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
GPY16_RS04370	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
GPY16_RS04375	ENOG4105KNE	Phosphatidate cytidylyltransferase
GPY16_RS04380	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
GPY16_RS04385	ENOG4105DZP	Membrane-associated zinc metalloprotease
GPY16_RS04390	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GPY16_RS04395	ENOG4108RFI	Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity)
GPY16_RS04400	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
GPY16_RS04405	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
GPY16_RS04410	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
GPY16_RS04415	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
GPY16_RS04420	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
GPY16_RS04425	ENOG4105C0B	DNA polymerase III (alpha subunit)
GPY16_RS04430	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
GPY16_RS04435	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
GPY16_RS04440	ENOG4105N7H	Cytochrome
GPY16_RS04445	ENOG4108YZA	Nitrogen regulatory protein pii
GPY16_RS04460	ENOG4105E9H	Lytic Murein transglycosylase
GPY16_RS04470	ENOG4105D1A	Methyltransferase
GPY16_RS04475	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
GPY16_RS04480	ENOG4108JDX	DNA polymerase iii, epsilon subunit
GPY16_RS04490	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
GPY16_RS04530	ENOG4107QPN	acyl-Coa dehydrogenase
GPY16_RS04535	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
GPY16_RS04540	ENOG4105E7A	Glutamine amidotransferase
GPY16_RS04545	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
GPY16_RS04550	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
GPY16_RS04560	ENOG4105C2W	permease
GPY16_RS04575	ENOG4105CS1	NAD(P)H quinone oxidoreductase
GPY16_RS04580	ENOG4105K89	arsenate reductase
GPY16_RS04585	ENOG4105ERG	peptidase m48, ste24p
GPY16_RS04600	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GPY16_RS04605	ENOG4105RH4	Glycine cleavage system transcriptional repressor
GPY16_RS04615	ENOG4107EG0	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
GPY16_RS04630	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
GPY16_RS04635	ENOG4105KUZ	arsenate reductase
GPY16_RS04660	ENOG4105EZR	dyp-type peroxidase family protein
GPY16_RS04665	ENOG4105I03	Flagellin
GPY16_RS04670	ENOG4105I03	Flagellin
GPY16_RS04675	ENOG4105I03	Flagellin
GPY16_RS04680	ENOG41063QE	flagellar protein FlaG
GPY16_RS04685	ENOG4107BRV	flagellar capping protein
GPY16_RS04695	ENOG4105MQ3	flagellar protein FliS
GPY16_RS04700	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GPY16_RS04705	ENOG4105BZU	Histidine kinase
GPY16_RS04710	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GPY16_RS04715	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
GPY16_RS04720	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
GPY16_RS04725	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
GPY16_RS04735	ENOG4108JIR	Flagellum-specific ATP synthase
GPY16_RS04755	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
GPY16_RS04760	ENOG4105DD5	Flagellar motor switch protein
GPY16_RS04765	ENOG4105VTB	flagellar biosynthesis protein fliO
GPY16_RS04770	ENOG4105CN7	Flagellar biosynthetic protein FliP
GPY16_RS04775	ENOG4105VS8	Flagellar biosynthetic protein fliq
GPY16_RS04780	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
GPY16_RS04785	ENOG4105D00	flagellar biosynthetic protein flhB
GPY16_RS04790	ENOG4105D7B	Flagellar biosynthesis protein flha
GPY16_RS04795	ENOG4105FZW	flagellar biosynthesis regulator FlhF
GPY16_RS04800	ENOG4107R21	site-determining protein
GPY16_RS04805	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GPY16_RS04810	ENOG4108VYJ	response regulator receiver protein
GPY16_RS04815	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
GPY16_RS04820	ENOG4105CBS	Chea signal transduction histidine kinase
GPY16_RS04825	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
GPY16_RS04830	ENOG4107QJE	Chromosome Partitioning Protein
GPY16_RS04840	ENOG4108V3W	Chemotaxis protein, CheW
GPY16_RS04855	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
GPY16_RS04860	ENOG41060IM	Heme exporter protein
GPY16_RS04865	ENOG4105X3C	heme exporter protein
GPY16_RS04870	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
GPY16_RS04875	ENOG4105DA4	cytochrome c-type biogenesis protein
GPY16_RS04880	ENOG4107QX9	Thiol disulfide interChange protein
GPY16_RS04885	ENOG4105KWW	Biogenesis protein
GPY16_RS04890	ENOG4108M1T	Cytochrome c-type biogenesis protein
GPY16_RS04895	ENOG410903C	(LipO)protein
GPY16_RS04900	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
GPY16_RS04905	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
GPY16_RS04920	ENOG4105CHU	acetyl-coa acetyltransferase
GPY16_RS04925	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
GPY16_RS04930	ENOG4108JQM	Insulinase (Peptidase family M16)
GPY16_RS04935	ENOG4108BY2	phosphohistidine phosphatase
GPY16_RS04945	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
GPY16_RS04950	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
GPY16_RS04955	ENOG4105EN6	Membrane
GPY16_RS04965	ENOG4105MH2	YfcL protein
GPY16_RS04970	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
GPY16_RS04975	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
GPY16_RS04980	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
GPY16_RS04985	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
GPY16_RS04995	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
GPY16_RS05000	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
GPY16_RS05005	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
GPY16_RS05010	ENOG4108S3P	Sporulation domain protein
GPY16_RS05015	ENOG4105E96	Colicin v production protein
GPY16_RS05020	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
GPY16_RS05025	ENOG4105EJC	lysr family transcriptional regulator
GPY16_RS05030	ENOG4105I93	response regulator
GPY16_RS05040	ENOG4105WD1	Membrane
GPY16_RS05045	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
GPY16_RS05050	ENOG4107QMP	dna polymerase iii subunits gamma and tau
GPY16_RS05060	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
GPY16_RS05075	ENOG4105JJR	Histidine kinase
GPY16_RS05080	ENOG4107EXC	regulatoR
GPY16_RS05085	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
GPY16_RS05090	ENOG4105KRS	Proteinase inhibitor
GPY16_RS05105	ENOG4108UYE	Lactoylglutathione lyase
GPY16_RS05115	ENOG4105G6Z	alkaline phosphatase
GPY16_RS05130	ENOG4105DHI	Methyltransferase
GPY16_RS05135	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
GPY16_RS05145	ENOG4105CJW	magnesium transporter
GPY16_RS05150	ENOG4105BZU	Histidine kinase
GPY16_RS05160	ENOG4105C8Q	Methyl-accepting chemotaxis
GPY16_RS05165	ENOG4108M3R	transcriptional activator CadC
GPY16_RS05170	ENOG4105D5Q	Arginine ornithine antiporter
GPY16_RS05175	ENOG4105CXN	decarboxylase
GPY16_RS05180	ENOG4105BZU	Histidine kinase
GPY16_RS05190	ENOG4105C59	p-type ATPase
GPY16_RS05195	ENOG4107SXA	Phosphorylase
GPY16_RS05205	ENOG4108NVR	Methyl-accepting chemotaxis
GPY16_RS05210	ENOG4105K59	histidine triad (HIT) protein
GPY16_RS05235	ENOG4105D0Y	UPF0227 protein
GPY16_RS05240	ENOG4105CEP	NADH dehydrogenase
GPY16_RS05265	ENOG4105D60	lipoprotein releasing system transmembrane protein
GPY16_RS05270	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
GPY16_RS05275	ENOG4105D60	lipoprotein releasing system transmembrane protein
GPY16_RS05285	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
GPY16_RS05290	ENOG4105BZ1	(ABC) transporter
GPY16_RS05300	ENOG4105W49	UPF0434 protein
GPY16_RS05310	ENOG4108KHP	Diguanylate cyclase
GPY16_RS05315	ENOG4105ED1	spovr family
GPY16_RS05325	ENOG4105CYN	Serine protein kinase
GPY16_RS05330	ENOG4105XWI	UPF0304 protein
GPY16_RS05340	ENOG4105F1A	Pyruvate formate-lyase
GPY16_RS05345	ENOG4108NVR	Methyl-accepting chemotaxis
GPY16_RS05355	ENOG4105C6N	Formate acetyltransferase
GPY16_RS05370	ENOG4108JEH	abc transporter atp-binding protein
GPY16_RS05375	ENOG4105E89	ABC transporter
GPY16_RS05380	ENOG4105DSP	amino acid AbC transporter
GPY16_RS05395	ENOG4105CGK	Exodeoxyribonuclease III
GPY16_RS05400	ENOG4105C8Q	Methyl-accepting chemotaxis
GPY16_RS05405	ENOG4106428	Protein of unknown function (DUF2496)
GPY16_RS05410	ENOG4108URS	primosomal replication protein n''
GPY16_RS05415	ENOG4105EJ9	Membrane
GPY16_RS05420	ENOG4105DVT	helicase
GPY16_RS05425	ENOG4105ZU8	porin-like protein H
GPY16_RS05435	ENOG4108R99	pseudouridine synthase
GPY16_RS05445	ENOG4105VEQ	Cold shock protein
GPY16_RS05450	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
GPY16_RS05455	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
GPY16_RS05460	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
GPY16_RS05470	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
GPY16_RS05485	ENOG4105RKX	Protein of unknown function (DUF2498)
GPY16_RS05490	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
GPY16_RS05500	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
GPY16_RS05520	ENOG4105HP8	regulator of competence-specific genes
GPY16_RS05525	ENOG4105ETE	Transcriptional regulator (LacI family
GPY16_RS05530	ENOG4109039	Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity)
GPY16_RS05535	ENOG4106WF9	DNA-binding transcriptional regulator TorR
GPY16_RS05540	ENOG4107S90	membrAne
GPY16_RS05545	ENOG4106371	Methyltransferase
GPY16_RS05555	ENOG4105DAH	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity)
GPY16_RS05570	ENOG4107RGH	Aldehyde dehydrogenase
GPY16_RS05590	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
GPY16_RS05595	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
GPY16_RS05610	ENOG4105C9M	aspartyl-trna synthetase
GPY16_RS05615	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
GPY16_RS05620	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
GPY16_RS05630	ENOG4105C4M	(Ubiquinol oxidase) subunit I
GPY16_RS05635	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
GPY16_RS05650	ENOG4107YD3	Thioesterase
GPY16_RS05655	ENOG4105E02	MotA TolQ exbB proton channel
GPY16_RS05660	ENOG4105M8F	Biopolymer transport protein exbD tolR
GPY16_RS05675	ENOG4105KCK	Peptidoglycan-associated lipoprotein
GPY16_RS05680	ENOG4105UFD	tol-pal system protein YbgF
GPY16_RS05695	ENOG4105Z6B	inner membrane protein yjfl
GPY16_RS05705	ENOG4106032	Glutathionylspermidine synthase
GPY16_RS05720	ENOG4108RNS	Exports L-alanine (By similarity)
GPY16_RS05795	ENOG4105YGK	Pfam:UPF0157
GPY16_RS05810	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
GPY16_RS05815	ENOG4105JAB	phenazine biosynthesis protein, phzf family
GPY16_RS05820	ENOG4105C8Q	Methyl-accepting chemotaxis
GPY16_RS05825	ENOG4105C5I	Dehydrogenase
GPY16_RS05830	ENOG4105EE5	Membrane protein terC
GPY16_RS05845	ENOG4108R6W	Transcriptional regulator, ARAC family
GPY16_RS05860	ENOG4105BZU	Histidine kinase
GPY16_RS05870	ENOG4105BZU	Histidine kinase
GPY16_RS05875	ENOG4105BZU	Histidine kinase
GPY16_RS05890	ENOG4105DZ2	Transcriptional regulator
GPY16_RS05895	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
GPY16_RS05900	ENOG4108DNC	Involved in acetate metabolism (By similarity)
GPY16_RS05905	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
GPY16_RS05920	ENOG4105C7J	ABC transporter, permease
GPY16_RS05925	ENOG4108JJB	ABC transporter
GPY16_RS05930	ENOG4107R28	alpha amylase, catalytic region
GPY16_RS05940	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
GPY16_RS05945	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
GPY16_RS05950	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
GPY16_RS05960	ENOG4105C05	Multifunctional regulator of fatty acid metabolism (By similarity)
GPY16_RS05965	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
GPY16_RS05990	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
GPY16_RS05995	ENOG4105EAQ	(twin-arginine translocation) pathway signal
GPY16_RS06000	ENOG4105C5X	domain protein
GPY16_RS06015	ENOG4105CH5	extracellular solute-binding protein, family 7
GPY16_RS06025	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
GPY16_RS06040	ENOG41067TZ	transcriptional regulator, MarR family
GPY16_RS06045	ENOG4105C94	Transporter
GPY16_RS06050	ENOG4105C8Q	Methyl-accepting chemotaxis
GPY16_RS06070	ENOG4105CGF	Aromatic amino acid aminotransferase
GPY16_RS06075	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
GPY16_RS06090	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
GPY16_RS06100	ENOG4105C5S	asparaginyl-tRNA synthetase
GPY16_RS06105	ENOG4108NVR	Methyl-accepting chemotaxis
GPY16_RS06110	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
GPY16_RS06120	ENOG4105BZU	Histidine kinase
GPY16_RS06125	ENOG4105EJQ	L-serine dehydratase
GPY16_RS06130	ENOG4105C44	Serine transporter
GPY16_RS06135	ENOG4105P8F	nudix hydrolase
GPY16_RS06145	ENOG4105BZU	Histidine kinase
GPY16_RS06150	ENOG4105CRQ	synthase (Component I)
GPY16_RS06165	ENOG4105CM6	amino acid regulated cytosolic protein
GPY16_RS06175	ENOG4108JU8	Transcriptional regulator
GPY16_RS06180	ENOG4105D9U	N-acetyltransferase
GPY16_RS06195	ENOG4105C8P	)-transporter
GPY16_RS06200	ENOG4105BZU	Histidine kinase
GPY16_RS06210	ENOG4105BZU	Histidine kinase
GPY16_RS06215	ENOG4108KMM	Diguanylate cyclase
GPY16_RS06225	ENOG4105CPI	Metal Dependent Phosphohydrolase
GPY16_RS06230	ENOG4105BZU	Histidine kinase
GPY16_RS06235	ENOG4105G0K	glycine radical enzyme YjjI family
GPY16_RS06240	ENOG41076CZ	activating enzyme
GPY16_RS06260	ENOG4105DHT	Metal Dependent Phosphohydrolase
GPY16_RS06265	ENOG4108NRW	Phospholipase, patatin family
GPY16_RS06275	ENOG4105CBD	Diacylglycerol kinase
GPY16_RS06280	ENOG4105E0U	tyrosine-specific transport protein
GPY16_RS06285	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
GPY16_RS06290	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
GPY16_RS06295	ENOG4108RMU	ferritin dps family protein
GPY16_RS06310	ENOG4105BZ1	(ABC) transporter
GPY16_RS06320	ENOG4105BZG	amino acid carrier protein
GPY16_RS06335	ENOG4105DAY	polysaccharide export protein
GPY16_RS06365	ENOG4107RA4	Glycosyl transferase (Group 1
GPY16_RS06390	ENOG4105BZU	Histidine kinase
GPY16_RS06420	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
GPY16_RS06425	ENOG4105CFG	Acts as a chaperone (By similarity)
GPY16_RS06435	ENOG4106TD9	Diguanylate cyclase
GPY16_RS06455	ENOG4105GNX	MltA-interacting MipA family protein
GPY16_RS06495	ENOG4107QMS	site-determining protein
GPY16_RS06545	ENOG4105CQ7	ATP-dependent helicase
GPY16_RS06570	ENOG4107IFA	Lipase (EC 3.1.1.3)
GPY16_RS06580	ENOG4105E5M	Multidrug resistance protein D
GPY16_RS06585	ENOG4105CYW	agmatinase
GPY16_RS06590	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
GPY16_RS06650	ENOG4105BZU	Histidine kinase
GPY16_RS06655	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
GPY16_RS06665	ENOG4107RH7	Nicotinate phosphoribosyltransferase
GPY16_RS06680	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
GPY16_RS06690	ENOG4105FQ6	thiopurine methyltransferase
GPY16_RS06695	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
GPY16_RS06700	ENOG4107T42	This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis (By similarity)
GPY16_RS06715	ENOG4108ZG0	Ompa motb domain protein
GPY16_RS06730	ENOG4105CQB	FAD linked oxidase domain protein
GPY16_RS06750	ENOG4105C84	Histidine ammonia-lyase
GPY16_RS06760	ENOG41088SP	formiminoglutamate hydrolase
GPY16_RS06775	ENOG4108N23	SpoOM-related protein
GPY16_RS06785	ENOG4105C22	threonyL-tRNA synthetase
GPY16_RS06790	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
GPY16_RS06795	ENOG41082NX	50s ribosomal protein l35
GPY16_RS06800	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
GPY16_RS06905	ENOG41080E2	ribosomal-protein-alanine acetyltransferase
GPY16_RS07020	ENOG410829K	Lysine exporter protein (Lyse ygga)
GPY16_RS07070	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
GPY16_RS07165	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
GPY16_RS07175	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
GPY16_RS07225	ENOG4108V5Q	transglutaminase-like protein
GPY16_RS07280	ENOG4105KNA	-acetyltransferase
GPY16_RS07420	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
GPY16_RS07475	ENOG4108R6K	riboflavin synthase, subunit alpha
GPY16_RS07485	ENOG4105FGM	Fructosamine kinase
GPY16_RS07495	ENOG4105BZU	Histidine kinase
GPY16_RS07505	ENOG4107TT5	NLP P60 protein
GPY16_RS07510	ENOG4105C8Q	Methyl-accepting chemotaxis
GPY16_RS07520	ENOG4106IUH	DTW domain containing protein
GPY16_RS07525	ENOG4105EZX	Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P (By similarity)
GPY16_RS07535	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
GPY16_RS07545	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
GPY16_RS07550	ENOG4107A5B	Binding-protein-dependent transport systems, inner membrane component
GPY16_RS07560	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GPY16_RS07565	ENOG4105BZU	Histidine kinase
GPY16_RS07580	ENOG4105C5H	ABC transporter
GPY16_RS07585	ENOG4105C8Q	Methyl-accepting chemotaxis
GPY16_RS07590	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
GPY16_RS07620	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
GPY16_RS07625	ENOG4105QAX	Iron-sulfur
GPY16_RS07660	ENOG4107RUE	extracellular solute-binding protein family 1
GPY16_RS07665	ENOG4107RUE	extracellular solute-binding protein family 1
GPY16_RS07670	ENOG4105D38	putrescine abc transporter
GPY16_RS07675	ENOG4105F38	ABC transporter, permease
GPY16_RS07680	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
GPY16_RS07690	ENOG4108UR8	BAX protein
GPY16_RS07700	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
GPY16_RS07705	ENOG4105Q9Y	Universal stress protein
GPY16_RS07710	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
GPY16_RS07725	ENOG4105C59	p-type ATPase
GPY16_RS07735	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
GPY16_RS07750	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
GPY16_RS07765	ENOG4105BZU	Histidine kinase
GPY16_RS07790	ENOG4105DAN	ATP-dependent protease
GPY16_RS07795	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
GPY16_RS07810	ENOG4105C5H	ABC transporter
GPY16_RS07825	ENOG4108T7E	Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity)
GPY16_RS07830	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
GPY16_RS07835	ENOG4105C7I	Dehydrogenase
GPY16_RS07845	ENOG4105CD8	aminopeptidase N
GPY16_RS07855	ENOG4105CN1	protease
GPY16_RS07860	ENOG41073DY	may be a structural element that influences the osmotic activation of ProP at a post-translational level (By similarity)
GPY16_RS07865	ENOG4108ZGC	gaf domain protein
GPY16_RS07870	ENOG4105BZ1	(ABC) transporter
GPY16_RS07875	ENOG4105H2K	paraquat-inducible protein a
GPY16_RS07880	ENOG4105DY2	Paraquat-inducible protein b
GPY16_RS07885	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
GPY16_RS07890	ENOG4105QNR	S1 RNA binding domain protein
GPY16_RS07905	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
GPY16_RS07910	ENOG4108VPT	UPF0234 protein
GPY16_RS07915	ENOG4105BZU	Histidine kinase
GPY16_RS07925	ENOG4105WN5	stage II sporulation protein
GPY16_RS07935	ENOG4107V1M	polysaccharide export protein
GPY16_RS07950	ENOG4105BZU	Histidine kinase
GPY16_RS07955	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GPY16_RS08000	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
GPY16_RS08050	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
GPY16_RS08055	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
GPY16_RS08060	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
GPY16_RS08065	ENOG4106YYS	transcriptional regulatory protein
GPY16_RS08070	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
GPY16_RS08085	ENOG4107V40	secretion protein, HlyD family
GPY16_RS08110	ENOG4105BZG	amino acid carrier protein
GPY16_RS08120	ENOG4108NIW	Leucine export protein LeuE
GPY16_RS08125	ENOG4105CTD	carboxy-peptidase
GPY16_RS08140	ENOG4105C26	Dehydrogenase
GPY16_RS08145	ENOG4107THI	3,4-dihydroxyphenylacetate 2,3-dioxygenase
GPY16_RS08170	ENOG4105ERH	Fumarylacetoacetate hydrolase
GPY16_RS08195	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
GPY16_RS08200	ENOG4108V8F	Transcriptional regulator, MarR family
GPY16_RS08205	ENOG4107UWN	reductase
GPY16_RS08260	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
GPY16_RS08265	ENOG4105GXZ	Ferredoxin-type protein NapH
GPY16_RS08270	ENOG4108BGM	Quinol dehydrogenase periplasmic component
GPY16_RS08280	ENOG4107QXX	ABC transporter
GPY16_RS08285	ENOG4105EZ7	amino acid ABC transporter
GPY16_RS08290	ENOG4105DRP	amino acid AbC transporter
GPY16_RS08295	ENOG4105CDA	abc transporter atp-binding protein
GPY16_RS08300	ENOG4108MN8	Membrane
GPY16_RS08305	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
GPY16_RS08315	ENOG4105C8Q	Methyl-accepting chemotaxis
GPY16_RS08345	ENOG4105BZU	Histidine kinase
GPY16_RS08355	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
GPY16_RS08360	ENOG410667J	hydrolase
GPY16_RS08365	ENOG4105C8Q	Methyl-accepting chemotaxis
GPY16_RS08385	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
GPY16_RS08390	ENOG4105C7F	AcnD-accessory protein PrpF
GPY16_RS08395	ENOG4108I0Z	Aconitate hydratase
GPY16_RS08400	ENOG4105BZN	citrate synthase
GPY16_RS08405	ENOG4105CR4	methylisocitrate lyase
GPY16_RS08435	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
GPY16_RS08470	ENOG4107SCJ	type I restriction enzyme EcoKI subunit R
GPY16_RS08560	ENOG4105WH1	Two component transcriptional regulator luxr family
GPY16_RS08575	ENOG4105C8Q	Methyl-accepting chemotaxis
GPY16_RS08595	ENOG4105EX2	Binding-protein-dependent transport systems, inner membrane component
GPY16_RS08605	ENOG4105E98	transcriptional regulator DeoR family
GPY16_RS08610	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
GPY16_RS08625	ENOG4105VEQ	Cold shock protein
GPY16_RS08630	ENOG4105BZU	Histidine kinase
GPY16_RS08665	ENOG4108RXX	maleylacetoacetate isomerase
GPY16_RS08675	ENOG4105F1J	Homogentisate 1,2-dioxygenase
GPY16_RS08680	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
GPY16_RS08685	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
GPY16_RS08690	ENOG4105CGH	5'-nucleotidase
GPY16_RS08700	ENOG41090FY	type IV pilus biogenesis stability protein PilW
GPY16_RS08710	ENOG4105EBA	Specifically methylates the adenine in position 1618 of 23S rRNA (By similarity)
GPY16_RS08715	ENOG4108VKG	metal-dependent hydrolase
GPY16_RS08725	ENOG4105DUM	transcriptional regulator, lysR family
GPY16_RS08730	ENOG4107QF7	multi-drug
GPY16_RS08750	ENOG4108IU2	vtamin B12-transporter permease
GPY16_RS08755	ENOG4107UI5	Transforms N(2)-succinylglutamate into succinate and glutamate (By similarity)
GPY16_RS08770	ENOG4108YZT	Adenosylcobinamide kinase
GPY16_RS08775	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
GPY16_RS08790	ENOG4105CJB	Exodeoxyribonuclease I
GPY16_RS08800	ENOG41067MG	lrgb family
GPY16_RS08810	ENOG4105C8V	SAICAR synthetase
GPY16_RS08825	ENOG4105CQ7	ATP-dependent helicase
GPY16_RS08835	ENOG4107GZ4	SanA protein
GPY16_RS08840	ENOG4105C8P	)-transporter
GPY16_RS08845	ENOG4105BZU	Histidine kinase
GPY16_RS08865	ENOG4105C3M	thioredoxin reductase
GPY16_RS08870	ENOG4108JJ9	ABC, transporter
GPY16_RS08875	ENOG4108JJ8	(ABC) transporter
GPY16_RS08880	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
GPY16_RS08890	ENOG4105BZU	Histidine kinase
GPY16_RS08890	ENOG4105BZU	Histidine kinase
GPY16_RS08915	ENOG4105DWU	Membrane
GPY16_RS08925	ENOG4105DY8	decarboxylase
GPY16_RS08930	ENOG4106KNT	transcriptional regulator
GPY16_RS08935	ENOG4107QW4	alcohol dehydrogenase
GPY16_RS08940	ENOG41090BQ	Glutaredoxin
GPY16_RS08955	ENOG4107QPN	acyl-Coa dehydrogenase
GPY16_RS08965	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
GPY16_RS08980	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
GPY16_RS08985	ENOG4105CGD	Nad-dependent epimerase dehydratase
GPY16_RS08995	ENOG4105C2C	drug resistance transporter, Bcr CflA
GPY16_RS09000	ENOG4105I08	Pseudouridine synthase
GPY16_RS09005	ENOG4105CFI	type iii restriction protein res subunit
GPY16_RS09015	ENOG4105ETX	regulatoR
GPY16_RS09020	ENOG4105JJR	Histidine kinase
GPY16_RS09025	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
GPY16_RS09040	ENOG4105BZU	Histidine kinase
GPY16_RS09050	ENOG4105XZD	Fe-S protein
GPY16_RS09060	ENOG4105VNH	ABC transporter solute-binding protein
GPY16_RS09065	ENOG4105CXZ	ABC transporter, permease
GPY16_RS09070	ENOG4108VGW	abc transporter atp-binding protein
GPY16_RS09075	ENOG4108T9J	Cdp-alcohol phosphatidyltransferase
GPY16_RS09080	ENOG4108JUA	Transcriptional regulator
GPY16_RS09090	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
GPY16_RS09100	ENOG4108W1A	pseudouridine synthase
GPY16_RS09110	ENOG4105C8J	)-transporter
GPY16_RS09120	ENOG4105C28	cystathionine
GPY16_RS09125	ENOG4108R3E	Dna-3-methyladenine glycosylase i
GPY16_RS09145	ENOG4105FM1	phage shock protein C
GPY16_RS09150	ENOG4105YYT	phage shock protein B
GPY16_RS09155	ENOG41087YS	Phage shock protein A
GPY16_RS09160	ENOG4105E51	psp operon transcriptional activator
GPY16_RS09165	ENOG4108J59	Extracellular solute-binding protein, family 5
GPY16_RS09170	ENOG4108I5W	peptide transport system, permease protein
GPY16_RS09175	ENOG4108EU3	peptide transport system, permease
GPY16_RS09180	ENOG4108JQ3	Peptide ABC transporter ATP-binding protein
GPY16_RS09185	ENOG4108JQ2	peptide transport system atp-binding protein
GPY16_RS09200	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
GPY16_RS09250	ENOG4105TMB	Formate nitrite transporter
GPY16_RS09270	ENOG4107NQ8	LysR family Transcriptional regulator
GPY16_RS09275	ENOG4108535	NAD dependent epimerase/dehydratase family
GPY16_RS09290	ENOG4105C8N	cysteinyl-tRNA synthetase
GPY16_RS09295	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
GPY16_RS09305	ENOG4105D58	Diguanylate phosphodiesterase
GPY16_RS09315	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
GPY16_RS09320	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
GPY16_RS09350	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
GPY16_RS09355	ENOG4107S6Z	Na H antiporter
GPY16_RS09360	ENOG4108SAU	DNA-binding protein H-ns
GPY16_RS09365	ENOG4107RE1	Inosine-guanosine kinase
GPY16_RS09380	ENOG41075W9	High frequency lysogenization protein HflD homolog
GPY16_RS09385	ENOG4107QTF	adenylosuccinate lyase
GPY16_RS09405	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
GPY16_RS09420	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
GPY16_RS09435	ENOG4105EWW	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
GPY16_RS09445	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
GPY16_RS09450	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
GPY16_RS09460	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
GPY16_RS09465	ENOG4105D1H	recombination factor protein RarA
GPY16_RS09470	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
GPY16_RS09475	ENOG4105CNU	cell division protein FtsK
GPY16_RS09480	ENOG4105EW9	transcriptional regulator AsnC family
GPY16_RS09485	ENOG4105DCF	alanine dehydrogenase
GPY16_RS09495	ENOG4107R11	Transcriptional regulator
GPY16_RS09505	ENOG4105FR9	TRNA-(Ms 2 io 6 A)-hydroxylase
GPY16_RS09520	ENOG4108JQ7	(ABC) transporter
GPY16_RS09535	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
GPY16_RS09540	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
GPY16_RS09550	ENOG4105CFV	Tetratricopeptide repeat protein
GPY16_RS09555	ENOG4105Q4A	inner membrane protein yciS
GPY16_RS09560	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
GPY16_RS09565	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
GPY16_RS09570	ENOG4105CAT	Cytidine monophosphate kinase
GPY16_RS09575	ENOG4105ERU	peptidase
GPY16_RS09580	ENOG4105UBK	short-chain dehydrogenase reductase
GPY16_RS09600	ENOG4107R88	Chemotaxis protein (CheV)
GPY16_RS09605	ENOG4105DAG	ROK family
GPY16_RS09610	ENOG4105CA9	Pyruvate kinase
GPY16_RS09615	ENOG4108NRW	Phospholipase, patatin family
GPY16_RS09630	ENOG4105C8J	)-transporter
GPY16_RS09645	ENOG4105CI1	PTS System
GPY16_RS09655	ENOG4107QRG	dna polymerase iii
GPY16_RS09660	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
GPY16_RS09665	ENOG4105HHA	aminodeoxychorismate lyase
GPY16_RS09675	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
GPY16_RS09680	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
GPY16_RS09685	ENOG4105CHR	reductase
GPY16_RS09690	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
GPY16_RS09700	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
GPY16_RS09705	ENOG4105VGS	50s ribosomal protein l32
GPY16_RS09710	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
GPY16_RS09715	ENOG4108UHJ	MAF-like protein
GPY16_RS09720	ENOG4105EI2	Pseudouridine synthase
GPY16_RS09725	ENOG4105C03	ribonuclease
GPY16_RS09730	ENOG4105CHH	sulfate transporter
GPY16_RS09740	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
GPY16_RS09750	ENOG4105DBI	uridine monophosphokinase
GPY16_RS09755	ENOG4105D1F	ATP-binding protein
GPY16_RS09775	ENOG4107QX9	Thiol disulfide interChange protein
GPY16_RS09780	ENOG4105DA4	cytochrome c-type biogenesis protein
GPY16_RS09785	ENOG4105DVI	reductase, NrfD
GPY16_RS09790	ENOG4105D3S	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
GPY16_RS09795	ENOG4105JJ8	Cytochrome c nitrite reductase, pentaheme subunit
GPY16_RS09800	ENOG4105EAU	Plays a role in nitrite reduction (By similarity)
GPY16_RS09815	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GPY16_RS09820	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
GPY16_RS09825	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
GPY16_RS09830	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
GPY16_RS09855	ENOG4105D3D	Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine (By similarity)
GPY16_RS09900	ENOG4105WH1	Two component transcriptional regulator luxr family
GPY16_RS09905	ENOG4105CQ2	DNA polymerase
GPY16_RS09920	ENOG4105FUQ	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
GPY16_RS09925	ENOG4108W5H	UPF0263 protein
GPY16_RS09930	ENOG4105FE9	pseudouridine synthase
GPY16_RS09940	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
GPY16_RS09945	ENOG4105DB7	PHP domain protein
GPY16_RS09955	ENOG4105CRQ	synthase (Component I)
GPY16_RS09960	ENOG4105DDQ	anthranilate synthase
GPY16_RS09970	ENOG4105DK0	Indole-3-glycerol phosphate synthase
GPY16_RS09975	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
GPY16_RS09980	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
GPY16_RS09985	ENOG4105CK2	sodium dicarboxylate symporter
GPY16_RS09995	ENOG4107835	probably involved in intracellular septation (By similarity)
GPY16_RS10000	ENOG4105NAU	thioesterase Superfamily protein
GPY16_RS10005	ENOG4105K9H	YciI-like protein
GPY16_RS10015	ENOG4105CHF	Glutathione S-transferase
GPY16_RS10020	ENOG4108JQ7	(ABC) transporter
GPY16_RS10025	ENOG4105C3U	ABC transporter
GPY16_RS10030	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
GPY16_RS10035	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
GPY16_RS10040	ENOG4107QSI	ABC, transporter
GPY16_RS10045	ENOG4108ZAF	Molybdopterin
GPY16_RS10050	ENOG4105M00	molybdopterin converting factor, subunit 1
GPY16_RS10060	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
GPY16_RS10065	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
GPY16_RS10070	ENOG4105CHW	UPF0052 protein
GPY16_RS10080	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GPY16_RS10085	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
GPY16_RS10095	ENOG4105DGN	Electron transport complex
GPY16_RS10100	ENOG4108R3D	Electron transport complex
GPY16_RS10110	ENOG4105D6A	Electron transport complex
GPY16_RS10120	ENOG4105DZB	Electron transport complex
GPY16_RS10125	ENOG4105CSM	endonuclease III
GPY16_RS10130	ENOG4108UYE	Lactoylglutathione lyase
GPY16_RS10135	ENOG4106WH9	Protein of unknown function (DUF2753)
GPY16_RS10140	ENOG4105EIY	sodium-type flagellar protein motY
GPY16_RS10150	ENOG4105D3Y	Na H antiporter
GPY16_RS10160	ENOG4105M2J	Glutaredoxin
GPY16_RS10165	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
GPY16_RS10175	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
GPY16_RS10180	ENOG4108EKI	Dehydrogenase
GPY16_RS10185	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
GPY16_RS10190	ENOG4105EYW	Ion transport protein
GPY16_RS10200	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
GPY16_RS10205	ENOG4105DFD	Na H antiporter
GPY16_RS10230	ENOG4105E68	Sulfatase
GPY16_RS10255	ENOG4105EYG	tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site (By similarity)
GPY16_RS10320	ENOG4107ZYR	domain protein
GPY16_RS10330	ENOG4105XEP	YhcH YjgK YiaL family protein
GPY16_RS10340	ENOG4105BZU	Histidine kinase
GPY16_RS10345	ENOG4105BZU	Histidine kinase
GPY16_RS10350	ENOG4105DGU	Histone deacetylase
GPY16_RS10355	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
GPY16_RS10360	ENOG41069NU	Nitroreductase
GPY16_RS10365	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
GPY16_RS10370	ENOG4105D07	Signal peptide peptidase, SppA
GPY16_RS10375	ENOG4105HDK	L-asparaginase
GPY16_RS10380	ENOG4105VUT	cytoplasmic protein
GPY16_RS10390	ENOG4105E0X	reductase
GPY16_RS10395	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
GPY16_RS10400	ENOG4105DSB	aldose 1-epimerase
GPY16_RS10405	ENOG4105C8Q	Methyl-accepting chemotaxis
GPY16_RS10445	ENOG4108MNP	Glycoprotein polysaccharide metabolism
GPY16_RS10450	ENOG4105C29	acyl-CoA thioesterase
GPY16_RS10460	ENOG4108XM1	transcriptional regulator AsnC family
GPY16_RS10465	ENOG4105C6T	cysteine synthase
GPY16_RS10480	ENOG4105BZS	acriflavin resistance protein
GPY16_RS10535	ENOG4105HMI	Membrane
GPY16_RS10540	ENOG4105CEY	Amp-dependent synthetase and ligase
GPY16_RS10545	ENOG4105DNI	Converts SHCHC to OSB (By similarity)
GPY16_RS10550	ENOG4108IPT	Naphthoate synthase
GPY16_RS10560	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
GPY16_RS10565	ENOG4105E4F	Isochorismate synthase
GPY16_RS10570	ENOG4105CHM	Aminotransferase
GPY16_RS10580	ENOG4105DK2	UPF0207 protein
GPY16_RS10710	ENOG410890F	Dynamin family
GPY16_RS10750	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
GPY16_RS10755	ENOG4106IUH	DTW domain containing protein
GPY16_RS10765	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
GPY16_RS10770	ENOG4105EIN	peptidylprolyl cis-trans isomerase
GPY16_RS10775	ENOG4105K70	DNA-binding protein
GPY16_RS10780	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
GPY16_RS10785	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
GPY16_RS10790	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
GPY16_RS10815	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
GPY16_RS10820	ENOG410835K	Tripartite ATP-Independent Periplasmic transporter DctQ
GPY16_RS10825	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
GPY16_RS10830	ENOG4108IJ9	(ABC) transporter
GPY16_RS10840	ENOG4105EQ7	Binding-protein-dependent transport systems, inner membrane component
GPY16_RS10850	ENOG4105E0F	Histidine kinase
GPY16_RS10855	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
GPY16_RS10860	ENOG4105CNG	UPF0061 protein
GPY16_RS10865	ENOG4105C8Q	Methyl-accepting chemotaxis
GPY16_RS10900	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
GPY16_RS10925	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
GPY16_RS10930	ENOG4105C84	Histidine ammonia-lyase
GPY16_RS10955	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
GPY16_RS10965	ENOG4105C2D	reductase
GPY16_RS10970	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
GPY16_RS10980	ENOG4105GR3	Histidine kinase
GPY16_RS10985	ENOG4105ETX	regulatoR
GPY16_RS10995	ENOG4105D9N	nucleoside
GPY16_RS11005	ENOG4105CVE	Lytic murein transglycosylase
GPY16_RS11010	ENOG4105VNG	YcgL domain-containing protein
GPY16_RS11015	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
GPY16_RS11020	ENOG4107QMS	site-determining protein
GPY16_RS11025	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
GPY16_RS11030	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
GPY16_RS11035	ENOG4105CEY	Amp-dependent synthetase and ligase
GPY16_RS11040	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
GPY16_RS11055	ENOG41072GX	Peptidase M22 Glycoprotease
GPY16_RS11060	ENOG4105DVT	helicase
GPY16_RS11070	ENOG4105CIY	formyltetrahydrofolate deformylase
GPY16_RS11075	ENOG4106ZCM	YecM protein
GPY16_RS11080	ENOG4105C75	arginyL-tRNA synthetase
GPY16_RS11095	ENOG4105CE1	Ferrous iron transport protein b
GPY16_RS11100	ENOG4105XFK	Ferrous iron transport protein A
GPY16_RS11110	ENOG4105NXV	High-affinity zinc uptake system protein
GPY16_RS11115	ENOG4105FDK	ABC transporter
GPY16_RS11120	ENOG4105FAV	ABC, transporter
GPY16_RS11125	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
GPY16_RS11130	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
GPY16_RS11135	ENOG4105C7S	Dehydrogenase
GPY16_RS11140	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
GPY16_RS11145	ENOG4105E33	succinate dehydrogenase
GPY16_RS11150	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
GPY16_RS11155	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
GPY16_RS11160	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
GPY16_RS11165	ENOG4105BZN	citrate synthase
GPY16_RS11170	ENOG4107QNR	UPF0135 protein
GPY16_RS11180	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
GPY16_RS11185	ENOG4107R6U	sodium dicarboxylate symporter
GPY16_RS11195	ENOG4105WWK	YheO domain protein
GPY16_RS11200	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
GPY16_RS11205	ENOG4107CDU	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity)
GPY16_RS11210	ENOG4105EV9	Alpha Beta Hydrolase
GPY16_RS11220	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
GPY16_RS11230	ENOG41090R7	Ferric uptake
GPY16_RS11240	ENOG4105CI1	PTS System
GPY16_RS11245	ENOG4105CE4	GlcNAc 6-P deacetylase
GPY16_RS11250	ENOG4105E2R	ROK family
GPY16_RS11255	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
GPY16_RS11260	ENOG4105CAQ	asparagine synthetase
GPY16_RS11270	ENOG4105DUX	Transporter
GPY16_RS11275	ENOG4105C8Q	Methyl-accepting chemotaxis
GPY16_RS11285	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
GPY16_RS11295	ENOG4108DQ1	activator toxR
GPY16_RS11315	ENOG4108RE9	Phosphodiesterase
GPY16_RS11340	ENOG4105ECP	epimerase
GPY16_RS11345	ENOG4105E1F	short-chain dehydrogenase reductase
GPY16_RS11355	ENOG4107QR8	Thioredoxin
GPY16_RS11360	ENOG4107QX8	SPFH domain, Band 7 family protein
GPY16_RS11375	ENOG41081QG	Porin Gram-negative type
GPY16_RS11380	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
GPY16_RS11385	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
GPY16_RS11390	ENOG4105EXN	Sulfate transport protein CysZ
GPY16_RS11395	ENOG4105C6T	cysteine synthase
GPY16_RS11400	ENOG4105KZ7	phosphocarrier protein hpr
GPY16_RS11405	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
GPY16_RS11410	ENOG4105C5Y	PTS System
GPY16_RS11420	ENOG4105I03	Flagellin
GPY16_RS11425	ENOG4105I03	Flagellin
GPY16_RS11430	ENOG4105DTJ	flagellar hook-associated protein
GPY16_RS11440	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
GPY16_RS11445	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
GPY16_RS11450	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
GPY16_RS11455	ENOG4105CGA	flagellar basal-body rod protein FlgG
GPY16_RS11460	ENOG4108KPB	Flagellar basal-body rod protein FlgF
GPY16_RS11465	ENOG4105BZE	flagellar hook protein, FlgE
GPY16_RS11470	ENOG4105W00	Flagellar hook capping protein
GPY16_RS11475	ENOG4108ZC9	flagellar basal-body rod protein flgc
GPY16_RS11480	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
GPY16_RS11485	ENOG4105BZU	Histidine kinase
GPY16_RS11490	ENOG4107R88	Chemotaxis protein (CheV)
GPY16_RS11535	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
GPY16_RS11545	ENOG41081QG	Porin Gram-negative type
GPY16_RS11550	ENOG4105C59	p-type ATPase
GPY16_RS11560	ENOG4105E2D	ec 3.2.1.52
GPY16_RS11565	ENOG4105MBR	gumn family
GPY16_RS11580	ENOG4108DG9	Smr protein MutS2
GPY16_RS11585	ENOG4105FE9	pseudouridine synthase
GPY16_RS11595	ENOG4105CGH	5'-nucleotidase
GPY16_RS11600	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
GPY16_RS11605	ENOG41063JG	Transcriptional regulator
GPY16_RS11610	ENOG4108YY7	Invasion gene expression up-regulator SirB
GPY16_RS11615	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
GPY16_RS11620	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
GPY16_RS11625	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
GPY16_RS11630	ENOG4105C1U	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
GPY16_RS11640	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
GPY16_RS11645	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
GPY16_RS11650	ENOG4105C3G	gtp-binding protein
GPY16_RS11730	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
GPY16_RS11740	ENOG4105C9A	Phoh family
GPY16_RS11750	ENOG4108JU5	Magnesium and cobalt efflux protein
GPY16_RS11755	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
GPY16_RS11760	ENOG4107PAI	alpha helical protein
GPY16_RS11770	ENOG4108U2H	Rare lipoprotein B
GPY16_RS11775	ENOG4105DJF	DNA polymerase III, delta' subunit
GPY16_RS11780	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
GPY16_RS11785	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
GPY16_RS11790	ENOG4105CJN	penicillin-binding protein
GPY16_RS11795	ENOG4105CNI	cell division protein FtsW
GPY16_RS11800	ENOG4105K6T	rare lipoprotein A
GPY16_RS11805	ENOG4105DZ1	carboxypeptidase
GPY16_RS11810	ENOG4108Z43	UPF0250 protein
GPY16_RS11820	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
GPY16_RS11830	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
GPY16_RS11860	ENOG4105CG3	alpha amylase, catalytic region
GPY16_RS11865	ENOG4105C5Y	PTS System
GPY16_RS11870	ENOG4105D4X	repressor
GPY16_RS11875	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
GPY16_RS11885	ENOG4108UMI	ABC transporter, permease
GPY16_RS11890	ENOG4105D01	(LipO)protein
GPY16_RS11895	ENOG4105EXF	Zn-ribbon-containing, possibly nucleic-acid-binding protein
GPY16_RS11900	ENOG4108T6E	Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function (By similarity)
GPY16_RS11915	ENOG4105BZU	Histidine kinase
GPY16_RS11920	ENOG4105EWT	decarboxylase family
GPY16_RS11935	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
GPY16_RS11940	ENOG4105M08	Membrane
GPY16_RS11950	ENOG4105ETT	transcriptional Regulator, LysR family
GPY16_RS11955	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
GPY16_RS11960	ENOG4106VK6	Flagellar motor protein
GPY16_RS11965	ENOG4105E14	MotA TolQ exbB proton channel
GPY16_RS11970	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
GPY16_RS11975	ENOG4105CTB	Polyprenyl synthetase
GPY16_RS11980	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
GPY16_RS11985	ENOG4108ZAI	phosphatidylglycerophosphatase a
GPY16_RS11990	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
GPY16_RS11995	ENOG4107YIM	Involved in the transcription termination process (By similarity)
GPY16_RS12000	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
GPY16_RS12015	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
GPY16_RS12025	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
GPY16_RS12030	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
GPY16_RS12035	ENOG4108UVK	Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32 (By similarity)
GPY16_RS12045	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
GPY16_RS12050	ENOG4105C7N	Xanthine uracil vitamin C permease
GPY16_RS12055	ENOG4105CIN	aminoacyl-histidine dipeptidase
GPY16_RS12080	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
GPY16_RS12085	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
GPY16_RS12095	ENOG4108Z6B	deaminase
GPY16_RS12100	ENOG4105CC0	LysR family Transcriptional regulator
GPY16_RS12110	ENOG4105C4W	S-formylglutathione hydrolase
GPY16_RS12115	ENOG4105CFC	Transporter
GPY16_RS12145	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
GPY16_RS12150	ENOG4105CFG	Acts as a chaperone (By similarity)
GPY16_RS12190	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
GPY16_RS12195	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
GPY16_RS12200	ENOG4105VDB	UPF0125 protein
GPY16_RS12205	ENOG4108Z1B	Cyclase dehydrase
GPY16_RS12210	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
GPY16_RS12250	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
GPY16_RS12270	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
GPY16_RS12275	ENOG4105BZG	amino acid carrier protein
GPY16_RS12280	ENOG4106HK8	GPR1 FUN34 yaaH family protein
GPY16_RS12295	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
GPY16_RS12310	ENOG410620I	Diguanylate cyclase
GPY16_RS12320	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
GPY16_RS12325	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
GPY16_RS12330	ENOG4105N21	Membrane
GPY16_RS12335	ENOG4105CUT	histidyl-tRNA synthetase
GPY16_RS12340	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
GPY16_RS12345	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
GPY16_RS12350	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
GPY16_RS12355	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
GPY16_RS12360	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
GPY16_RS12365	ENOG4105WVQ	Fe-S assembly protein IscX
GPY16_RS12370	ENOG4108ZIT	Ferredoxin, 2FE-2S
GPY16_RS12380	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
GPY16_RS12385	ENOG4108Z4V	iron-sulfur cluster assembly
GPY16_RS12390	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
GPY16_RS12395	ENOG4105C3J	Cysteine desulfurase
GPY16_RS12400	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
GPY16_RS12405	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
GPY16_RS12410	ENOG4105ECY	inositol monophosphatase
GPY16_RS12415	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
GPY16_RS12420	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
GPY16_RS12425	ENOG4105VIE	preprotein translocase, subunit YajC
GPY16_RS12430	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
GPY16_RS12445	ENOG4105W87	Cbs domain
GPY16_RS12450	ENOG4108I9X	Isocitrate lyase
GPY16_RS12455	ENOG4107QP3	malate synthase g
GPY16_RS12460	ENOG4105C5Q	Transcriptional regulator
GPY16_RS12465	ENOG4105D3R	alkyl hydroperoxide reductase
GPY16_RS12470	ENOG4106N3A	copper homeostasis protein cutc
GPY16_RS12475	ENOG4105CSR	polyphosphate kinase 2
GPY16_RS12485	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
GPY16_RS12490	ENOG4105E2Z	phosphate ABC transporter (Permease
GPY16_RS12495	ENOG4105C8U	phosphate abc transporter
GPY16_RS12505	ENOG4105C9X	ppx gppa phosphatase
GPY16_RS12515	ENOG4105BZU	Histidine kinase
GPY16_RS12520	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
GPY16_RS12525	ENOG4105DH7	May be involved in recombination (By similarity)
GPY16_RS12530	ENOG4105CFP	Peptidase U32
GPY16_RS12535	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
GPY16_RS12575	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
GPY16_RS12580	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
GPY16_RS12585	ENOG4105C34	Pseudouridine synthase
GPY16_RS12590	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GPY16_RS12595	ENOG4108WPH	sigma 54 modulation protein ribosomal protein S30EA
GPY16_RS12610	ENOG4105R9M	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity)
GPY16_RS12615	ENOG4107SC1	transglycosylase
GPY16_RS12620	ENOG4105C5H	ABC transporter
GPY16_RS12630	ENOG4105DR5	peptidase
GPY16_RS12635	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
GPY16_RS12640	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
GPY16_RS12645	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
GPY16_RS12675	ENOG4108HRK	Histidine kinase
GPY16_RS12680	ENOG4108NEV	two component transcriptional regulator, LytTR family
GPY16_RS12685	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
GPY16_RS12690	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
GPY16_RS12695	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
GPY16_RS12705	ENOG4105DTN	riboflavin biosynthesis protein ribF
GPY16_RS12710	ENOG4105CJR	Integral membrane protein (MviN
GPY16_RS12715	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
GPY16_RS12720	ENOG41080HT	Transcriptional regulator, arsr family
GPY16_RS12725	ENOG41063Z6	transcriptional regulator, lysR family
GPY16_RS12745	ENOG4108HE4	integrase family
GPY16_RS12765	ENOG4105C7H	Helicase, RecD TraA family
GPY16_RS12775	ENOG4105EFX	secretion protein, HlyD family
GPY16_RS12800	ENOG4105CAF	HipA N-terminal domain protein
GPY16_RS12825	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
GPY16_RS12835	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
GPY16_RS12840	ENOG4105HF0	Membrane
GPY16_RS12845	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
GPY16_RS12850	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
GPY16_RS12855	ENOG4105IRT	Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair (By similarity)
GPY16_RS12865	ENOG4105CPC	Aldo Keto reductase
GPY16_RS12890	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
GPY16_RS12895	ENOG4105T95	Thiol disulfide interChange protein
GPY16_RS12900	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
GPY16_RS12905	ENOG41071R3	Low-potential electron donor to a number of redox enzymes (By similarity)
GPY16_RS12910	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
GPY16_RS12915	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
GPY16_RS12920	ENOG4105C1J	atp-dependent rna helicase
GPY16_RS12930	ENOG4105BZG	amino acid carrier protein
GPY16_RS12945	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
GPY16_RS12950	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
GPY16_RS12955	ENOG4108VKA	Acts as a radical domain for damaged PFL and possibly other radical proteins (By similarity)
GPY16_RS12960	ENOG4105D98	threonine synthase
GPY16_RS12965	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
GPY16_RS12980	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
GPY16_RS12995	ENOG41065U4	response regulator
GPY16_RS13005	ENOG4105BZU	Histidine kinase
GPY16_RS13015	ENOG4105N5T	Radical SAM Protein
GPY16_RS13030	ENOG4105CBC	glutamate synthase
GPY16_RS13035	ENOG4105BZ8	glutamate synthase
GPY16_RS13050	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
GPY16_RS13055	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
GPY16_RS13060	ENOG4105EN6	Membrane
GPY16_RS13065	ENOG4105VP0	transcriptional regulator, lysR family
GPY16_RS13070	ENOG4105EJ9	Membrane
GPY16_RS13080	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
GPY16_RS13090	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
GPY16_RS13095	ENOG4105M6F	mutator MutT protein
GPY16_RS13110	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
GPY16_RS13115	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
GPY16_RS13120	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
GPY16_RS13125	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
GPY16_RS13135	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
GPY16_RS13145	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
GPY16_RS13155	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
GPY16_RS13160	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
GPY16_RS13165	ENOG4105CJN	penicillin-binding protein
GPY16_RS13170	ENOG41063Y6	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
GPY16_RS13175	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
GPY16_RS13185	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
GPY16_RS13195	ENOG41082RQ	UPF0102 protein
GPY16_RS13200	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
GPY16_RS13205	ENOG4105W4M	Transport-associated protein
GPY16_RS13210	ENOG4105KB2	stringent starvation protein b
GPY16_RS13215	ENOG4107MKT	Stringent starvation protein a
GPY16_RS13220	ENOG4105EIX	cytochrome c1
GPY16_RS13225	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
GPY16_RS13230	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
GPY16_RS13235	ENOG4108UJD	30S ribosomal protein S9
GPY16_RS13240	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
GPY16_RS13250	ENOG4105D6Z	AFG1 family ATPase
GPY16_RS13255	ENOG4108W2Q	Cytochrome d ubiquinol oxidase subunit III
GPY16_RS13260	ENOG4105C0H	protease
GPY16_RS13265	ENOG4105C0H	protease
GPY16_RS13270	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GPY16_RS13275	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GPY16_RS13280	ENOG4105IPS	esterase
GPY16_RS13285	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
GPY16_RS13290	ENOG4108SX3	cytoplasmic protein
GPY16_RS13295	ENOG41087AY	ADP-Ribose pyrophosphatase
GPY16_RS13300	ENOG4105DFG	type I secretion outer membrane protein
GPY16_RS13305	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
GPY16_RS13325	ENOG4105I7R	Adenylate cyclase
GPY16_RS13330	ENOG4107IX6	phosphate transport regulator
GPY16_RS13335	ENOG4105CJ3	phosphate transporter
GPY16_RS13340	ENOG4106MWK	domain protein
GPY16_RS13355	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
GPY16_RS13360	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GPY16_RS13365	ENOG4107ZVW	dihydroneopterin aldolase
GPY16_RS13370	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
GPY16_RS13375	ENOG4108WC5	Alpha Beta Hydrolase Fold protein
GPY16_RS13380	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
GPY16_RS13385	ENOG4105VCC	30S ribosomal protein S21
GPY16_RS13390	ENOG4105KTH	gatB Yqey
GPY16_RS13395	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
GPY16_RS13400	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GPY16_RS13430	ENOG4105CH5	extracellular solute-binding protein, family 7
GPY16_RS13435	ENOG4105CTS	PTS system mannitol-specific
GPY16_RS13440	ENOG4107SQ3	mannitol-1-phosphate 5-dehydrogenase
GPY16_RS13445	ENOG4105E61	Mannitol repressor protein
GPY16_RS13450	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
GPY16_RS13455	ENOG410804X	Transcriptional regulator
GPY16_RS13460	ENOG4105CA9	Pyruvate kinase
GPY16_RS13470	ENOG4105BZU	Histidine kinase
GPY16_RS13475	ENOG4108ZP8	Acetolactate synthase small subunit
GPY16_RS13480	ENOG4105C7K	acetolactate synthase
GPY16_RS13485	ENOG4108IQE	Amp-dependent synthetase and ligase
GPY16_RS13490	ENOG41064T2	transcriptional regulator, lysR family
GPY16_RS13510	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
GPY16_RS13520	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
GPY16_RS13535	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
GPY16_RS13540	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
GPY16_RS13545	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
GPY16_RS13555	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
GPY16_RS13560	ENOG4105NWN	ApaG protein
GPY16_RS13565	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
GPY16_RS13575	ENOG4107XM3	UPF0442 protein
GPY16_RS13585	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GPY16_RS13590	ENOG4105K46	50S ribosomal protein l27
GPY16_RS13595	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
GPY16_RS13600	ENOG4105EAH	synthase
GPY16_RS13610	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
GPY16_RS13625	ENOG41081QV	Universal stress protein
GPY16_RS13630	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
GPY16_RS13635	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
GPY16_RS13640	ENOG4105VFK	BolA family
GPY16_RS13650	ENOG4105E3I	toluene tolerance
GPY16_RS13655	ENOG4107PE3	Mammalian cell entry related domain protein
GPY16_RS13660	ENOG4105CY3	ABC transporter, permease
GPY16_RS13665	ENOG4105DHJ	ABC, transporter
GPY16_RS13675	ENOG4105C2X	Arabinose 5-phosphate isomerase
GPY16_RS13690	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
GPY16_RS13695	ENOG4108IUZ	ABC transporter
GPY16_RS13700	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GPY16_RS13705	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
GPY16_RS13710	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
GPY16_RS13720	ENOG41080Z8	PHOSPHOCARRIER protein
GPY16_RS13725	ENOG4105CJW	magnesium transporter
GPY16_RS13740	ENOG4107T0D	ABC, transporter
GPY16_RS13745	ENOG4106SMU	thiamine transporter membrane protein
GPY16_RS13750	ENOG4105DP9	ABC transporter
GPY16_RS13755	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
GPY16_RS13760	ENOG4105DFU	Cell wall formation (By similarity)
GPY16_RS13765	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
GPY16_RS13770	ENOG4105F0N	pyrophosphate phospho-hydrolase
GPY16_RS13780	ENOG41066HZ	AIG2-like family
GPY16_RS13785	ENOG4105MA0	exported protein
GPY16_RS13790	ENOG4105CFU	surface antigen
GPY16_RS13795	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
GPY16_RS13805	ENOG4108UUE	Transcriptional regulator
GPY16_RS13820	ENOG4108EE5	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
GPY16_RS13840	ENOG4107UCJ	Catalyzes the synthesis of activated sulfate (By similarity)
GPY16_RS13855	ENOG4105C11	sulfate adenylyltransferase), subunit 2
GPY16_RS13860	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
GPY16_RS13865	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
GPY16_RS13875	ENOG4107YB6	acetyltransferase, (GNAT) family
GPY16_RS13885	ENOG4108UBT	opacity-associated protein
GPY16_RS13890	ENOG4108V1T	peptidylprolyl cis-trans isomerase
GPY16_RS13900	ENOG4108ZT0	50S ribosomal protein l17
GPY16_RS13905	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
GPY16_RS13910	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
GPY16_RS13915	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
GPY16_RS13920	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GPY16_RS13930	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
GPY16_RS13935	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
GPY16_RS13940	ENOG4105VPB	50S ribosomal protein L30
GPY16_RS13945	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
GPY16_RS13950	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
GPY16_RS13955	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
GPY16_RS13960	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
GPY16_RS13965	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
GPY16_RS13970	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GPY16_RS13975	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
GPY16_RS13980	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
GPY16_RS13985	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
GPY16_RS13990	ENOG41083MP	50s ribosomal protein l29
GPY16_RS13995	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
GPY16_RS14000	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
GPY16_RS14005	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
GPY16_RS14010	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
GPY16_RS14015	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GPY16_RS14020	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
GPY16_RS14025	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
GPY16_RS14035	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
GPY16_RS14040	ENOG4105F88	accessory colonization factor AcfD
GPY16_RS14065	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
GPY16_RS14075	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
GPY16_RS14080	ENOG4108Z7G	MaoC domain protein dehydratase
GPY16_RS14085	ENOG4107WZ3	Transferase
GPY16_RS14090	ENOG4105D3Q	Sugar transferase
GPY16_RS14095	ENOG4105CGN	Glycosyl transferase (Group 1
GPY16_RS14100	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
GPY16_RS14140	ENOG4107QQG	Dehydrogenase
GPY16_RS14145	ENOG4105D75	Capsular exopolysaccharide family
GPY16_RS14160	ENOG4105DAY	polysaccharide export protein
GPY16_RS14170	ENOG4108Y9B	(LipO)protein
GPY16_RS14180	ENOG4105E3R	(LipO)protein
GPY16_RS14185	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
GPY16_RS14190	ENOG4105NWR	lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase
GPY16_RS14195	ENOG4105XA0	heptosyltransferase ii
GPY16_RS14200	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
GPY16_RS14220	ENOG4105F0R	Cytidylyltransferase
GPY16_RS14225	ENOG4107V9E	glucose-1-phosphate thymidylyltransferase
GPY16_RS14240	ENOG4107SE4	UDP-N-acetylglucosamine 2-epimerase
GPY16_RS14245	ENOG4105D2T	synthase
GPY16_RS14255	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
GPY16_RS14270	ENOG4105E68	Sulfatase
GPY16_RS14280	ENOG41080IJ	Diacylglycerol kinase
GPY16_RS14285	ENOG4105DKP	glycosyl transferase, family 9
GPY16_RS14290	ENOG4106WTF	Glycosyl transferase, family 2
GPY16_RS14295	ENOG4105M5K	heptosyltransferase
GPY16_RS14300	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
GPY16_RS14310	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
GPY16_RS14320	ENOG4105W0E	50S ribosomal protein L33
GPY16_RS14325	ENOG4105KDC	50s ribosomal protein l28
GPY16_RS14335	ENOG4105C8Q	Methyl-accepting chemotaxis
GPY16_RS14340	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
GPY16_RS14345	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
GPY16_RS14350	ENOG4105D1S	lipid A biosynthesis
GPY16_RS14355	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
GPY16_RS14360	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
GPY16_RS14365	ENOG4105DSJ	YicC domain protein
GPY16_RS14370	ENOG4105DWP	Membrane
GPY16_RS14385	ENOG4108JQ7	(ABC) transporter
GPY16_RS14395	ENOG4107QRA	Extracellular solute-binding protein, family 5
GPY16_RS14400	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
GPY16_RS14405	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
GPY16_RS14410	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
GPY16_RS14430	ENOG4109015	Biopolymer transport protein exbD tolR
GPY16_RS14445	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
GPY16_RS14450	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
GPY16_RS14455	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
GPY16_RS14460	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
GPY16_RS14465	ENOG4105CB5	ATP-dependent DNA helicase recG
GPY16_RS14470	ENOG4105C2W	permease
GPY16_RS14475	ENOG4105E0F	Histidine kinase
GPY16_RS14480	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
GPY16_RS14485	ENOG4105D17	glycoside hydrolase, family 3 domain protein
GPY16_RS14490	ENOG4105CNN	ABC, transporter
GPY16_RS14495	ENOG4105C2J	ABC transporter
GPY16_RS14510	ENOG4108Z6Z	Transcriptional regulator
GPY16_RS14515	ENOG4105EMU	Dehydrogenase
GPY16_RS14520	ENOG4108RRZ	Transcription elongation factor GreB
GPY16_RS14525	ENOG4105BZM	domain protein
GPY16_RS14545	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
GPY16_RS14550	ENOG4107RK2	ADP-ribose diphosphatase NudE
GPY16_RS14555	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
GPY16_RS14560	ENOG4105PIC	general secretion pathway protein N
GPY16_RS14565	ENOG4105U1E	general secretion pathway protein M
GPY16_RS14570	ENOG4108BY5	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins (By similarity)
GPY16_RS14575	ENOG4108RTD	type II secretion system protein K
GPY16_RS14580	ENOG4108WWZ	General secretion pathway protein J
GPY16_RS14585	ENOG4105X5Z	General secretion pathway protein I
GPY16_RS14590	ENOG4105VWV	general secretion pathway protein h
GPY16_RS14595	ENOG4108VAU	general secretion pathway protein G
GPY16_RS14600	ENOG4105D7Q	type ii secretion system
GPY16_RS14605	ENOG4107QHF	type ii secretion system protein e
GPY16_RS14615	ENOG4108XKW	General secretion pathway protein C
GPY16_RS14620	ENOG4105VEJ	Heat shock protein
GPY16_RS14625	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
GPY16_RS14630	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
GPY16_RS14640	ENOG4105SUU	thioesterase domain
GPY16_RS14645	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
GPY16_RS14670	ENOG4105C5F	glutamine synthetase
GPY16_RS14680	ENOG4105CUX	Signal transduction histidine kinase
GPY16_RS14685	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GPY16_RS14690	ENOG4105BZU	Histidine kinase
GPY16_RS14695	ENOG4105D4P	Coproporphyrinogen iii oxidase
GPY16_RS14700	ENOG4105XCT	Protein of unknown function (DUF2489)
GPY16_RS14705	ENOG4105ZR3	A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis (By similarity)
GPY16_RS14715	ENOG4106RE7	Cytochrome
GPY16_RS14725	ENOG4105C2M	dna polymerase I
GPY16_RS14730	ENOG4105D52	delta-aminolevulinic acid dehydratase
GPY16_RS14735	ENOG4105F8V	Hydrolase, tatD family
GPY16_RS14740	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
GPY16_RS14745	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
GPY16_RS14755	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
GPY16_RS14760	ENOG4105JC1	sterol-binding domain protein
GPY16_RS14765	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
GPY16_RS14770	ENOG4105CGY	Dna recombination protein
GPY16_RS14845	ENOG4107QK7	reductase
GPY16_RS14855	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
GPY16_RS14865	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
GPY16_RS14870	ENOG4105K63	Thioredoxin
GPY16_RS14875	ENOG4105C1J	atp-dependent rna helicase
GPY16_RS14880	ENOG4105C9X	ppx gppa phosphatase
GPY16_RS14885	ENOG4105EX9	Membrane
GPY16_RS14895	ENOG4105C9U	ATP-dependent DNA helicase RecQ
GPY16_RS14900	ENOG4105FR1	rard protein
GPY16_RS14920	ENOG4105C4R	Atp-dependent dna helicase
GPY16_RS14930	ENOG4105E18	UPF0276 protein
GPY16_RS14950	ENOG4105C2C	drug resistance transporter, Bcr CflA
GPY16_RS14960	ENOG4105DC7	peptidase M24
GPY16_RS14960	ENOG4105DC7	peptidase M24
GPY16_RS14965	ENOG4105D41	biosynthesis protein thiH
GPY16_RS14970	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
GPY16_RS14980	ENOG4105D06	uba thif-type nad fad binding protein
GPY16_RS14990	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
GPY16_RS14995	ENOG4105WMR	Protein CrcB homolog
GPY16_RS15000	ENOG4107R16	Multicopper oxidase
GPY16_RS15060	ENOG4105QNF	Outer membrane lipoprotein
GPY16_RS15100	ENOG4108Q9V	regulatoR
GPY16_RS15105	ENOG4105BZU	Histidine kinase
GPY16_RS15110	ENOG4108Q9V	regulatoR
GPY16_RS15115	ENOG4105BZU	Histidine kinase
GPY16_RS15120	ENOG4105BZU	Histidine kinase
GPY16_RS15125	ENOG4105H4F	exported protein
GPY16_RS15135	ENOG4108JJA	ABC, transporter
GPY16_RS15140	ENOG4107QZV	Type I secretion membrane fusion protein
GPY16_RS15145	ENOG4105DFG	type I secretion outer membrane protein
GPY16_RS15165	ENOG4105D64	Mechanosensitive ion channel
GPY16_RS15175	ENOG4108NVR	Methyl-accepting chemotaxis
GPY16_RS15180	ENOG4105YE1	PilZ domain
GPY16_RS15190	ENOG4108MK9	spermidine N(1)-acetyltransferase
GPY16_RS15195	ENOG4107RE3	peptidase, S41
GPY16_RS15220	ENOG4105EFX	secretion protein, HlyD family
GPY16_RS15225	ENOG4105KK7	inner membrane protein YiaW
GPY16_RS15230	ENOG4106TD9	Diguanylate cyclase
GPY16_RS15245	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
GPY16_RS15250	ENOG4107SEY	Conserved Protein
GPY16_RS15255	ENOG4108XDN	Transcriptional regulator
GPY16_RS15260	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
GPY16_RS15265	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
GPY16_RS15275	ENOG4105C1J	atp-dependent rna helicase
GPY16_RS15305	ENOG4105C8Q	Methyl-accepting chemotaxis
GPY16_RS15315	ENOG4107S17	Phosphate-binding protein
GPY16_RS15320	ENOG4105C8U	phosphate abc transporter
GPY16_RS15325	ENOG4105E2Z	phosphate ABC transporter (Permease
GPY16_RS15345	ENOG4107QVM	von Willebrand factor, type A
GPY16_RS15365	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
GPY16_RS15370	ENOG4105C8Q	Methyl-accepting chemotaxis
GPY16_RS15380	ENOG41086KC	Transcriptional regulator
GPY16_RS15385	ENOG41086KC	Transcriptional regulator
GPY16_RS15395	ENOG4108JJ6	Type I secretion system ATPase
GPY16_RS15400	ENOG4107QZV	Type I secretion membrane fusion protein
GPY16_RS15430	ENOG4105D75	Capsular exopolysaccharide family
GPY16_RS15445	ENOG4105D3Q	Sugar transferase
GPY16_RS15450	ENOG4108IJ9	(ABC) transporter
GPY16_RS15455	ENOG4107FKK	extracellular solute-binding protein family 1
GPY16_RS15460	ENOG4105D56	permease protein
GPY16_RS15465	ENOG4105EG2	ABC transporter, permease
GPY16_RS15495	ENOG4105CKW	Inner membrane protein yedI
GPY16_RS15510	ENOG4105QVC	MOSC domain-containing protein
GPY16_RS15510	ENOG4105QVC	MOSC domain-containing protein
GPY16_RS15565	ENOG4105EHG	Permease protein
GPY16_RS15575	ENOG4106GFD	transport protein
GPY16_RS15580	ENOG41090AP	transport protein
GPY16_RS15585	ENOG4105WQ5	TonB family
GPY16_RS15590	ENOG4105D4P	Coproporphyrinogen iii oxidase
GPY16_RS15595	ENOG41090JE	Utilization Protein
GPY16_RS15600	ENOG4105PYN	Pyridoxamine 5-phosphate oxidase-related
GPY16_RS15610	ENOG4107R88	Chemotaxis protein (CheV)
GPY16_RS15615	ENOG4105KQ5	peptidylprolyl cis-trans isomerase
GPY16_RS15620	ENOG4108M6U	Universal stress protein A
GPY16_RS15630	ENOG4105C8Q	Methyl-accepting chemotaxis
GPY16_RS15635	ENOG4105C8Q	Methyl-accepting chemotaxis
GPY16_RS15650	ENOG4105DWD	nucleoside recognition domain protein
GPY16_RS15670	ENOG4105DR5	peptidase
GPY16_RS15675	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
GPY16_RS15680	ENOG4105IH7	synthase
GPY16_RS15690	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
GPY16_RS15715	ENOG4105D9N	nucleoside
GPY16_RS15730	ENOG4105BZU	Histidine kinase
GPY16_RS15735	ENOG4108N3W	hemolysin secretion protein
GPY16_RS15750	ENOG4106TD9	Diguanylate cyclase
GPY16_RS15755	ENOG4105E0X	reductase
GPY16_RS15760	ENOG4108UKZ	OsmC family
GPY16_RS15765	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
GPY16_RS15780	ENOG4105JQN	Transcriptional regulator
GPY16_RS15785	ENOG4105PAD	Hydrolase
GPY16_RS15800	ENOG4108NVR	Methyl-accepting chemotaxis
GPY16_RS15810	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
GPY16_RS15815	ENOG410874W	AraC family transcriptional regulator
GPY16_RS15820	ENOG4108KAZ	Involved in phosphonate degradation (By similarity)
GPY16_RS15825	ENOG4108JPW	Aminotransferase
GPY16_RS15830	ENOG4107STF	Involved in phosphonate degradation (By similarity)
GPY16_RS15845	ENOG4107RCV	ABC transporter, permease
GPY16_RS15860	ENOG4105CJP	fad dependent oxidoreductase
GPY16_RS15865	ENOG4105ETT	transcriptional Regulator, LysR family
GPY16_RS15875	ENOG4105DUX	Transporter
GPY16_RS15880	ENOG4105EJQ	L-serine dehydratase
GPY16_RS15900	ENOG4105DZ1	carboxypeptidase
GPY16_RS15930	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
GPY16_RS15945	ENOG4108IJ7	Glycine betaine
GPY16_RS15950	ENOG4108KBJ	Inner membrane protein YkgB
GPY16_RS15965	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
GPY16_RS15985	ENOG4107R5Y	anaerobic glycerol-3-phosphate dehydrogenase, subunit A
GPY16_RS15995	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
GPY16_RS16010	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
GPY16_RS16025	ENOG4105C0A	alcohol dehydrogenase
GPY16_RS16030	ENOG4105R8A	Heat shock protein
GPY16_RS16035	ENOG4105K8Z	Phage shock protein
GPY16_RS16060	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
GPY16_RS16065	ENOG4105BZS	acriflavin resistance protein
GPY16_RS16070	ENOG4107PU6	Membrane
GPY16_RS16095	ENOG4105C44	Serine transporter
GPY16_RS16100	ENOG4105MEW	serine threonine protein phosphatase
GPY16_RS16110	ENOG4105C8Q	Methyl-accepting chemotaxis
GPY16_RS16120	ENOG4108M1A	Chitin-binding protein
GPY16_RS16125	ENOG4105FR1	rard protein
GPY16_RS16135	ENOG41060QA	UPF0267 protein
GPY16_RS16140	ENOG4106CKV	Pap2 superfamily protein
GPY16_RS16150	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
GPY16_RS16155	ENOG4107RGH	Aldehyde dehydrogenase
GPY16_RS16160	ENOG4106RE7	Cytochrome
GPY16_RS16165	ENOG4105C5W	Aldolase
GPY16_RS16175	ENOG4107R4Q	Functions as an ATPase. May play a role in metal insertion (metal-chelatase) or as a chaperone (By similarity)
GPY16_RS16180	ENOG4105EV2	VWA domain protein interacting with AAA ATPase
GPY16_RS16185	ENOG4105MSB	protein, conserved in bacteria
GPY16_RS16200	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
GPY16_RS16210	ENOG4105CNN	ABC, transporter
GPY16_RS16215	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
GPY16_RS16220	ENOG4108RVA	ribokinase
GPY16_RS16225	ENOG4105ETE	Transcriptional regulator (LacI family
GPY16_RS16235	ENOG4107R88	Chemotaxis protein (CheV)
GPY16_RS16245	ENOG41080E2	ribosomal-protein-alanine acetyltransferase
GPY16_RS16250	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
GPY16_RS16260	ENOG4107RFY	SbcCD D subunit
GPY16_RS16265	ENOG4105EYH	Exonuclease
GPY16_RS16380	ENOG4107QPK	)-transporter
GPY16_RS16385	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
GPY16_RS16390	ENOG4106YYS	transcriptional regulatory protein
GPY16_RS16395	ENOG4108UW5	maltose o-acetyltransferase
GPY16_RS16415	ENOG4105DHS	permease protein
GPY16_RS16420	ENOG4105CM4	permease protein
GPY16_RS16425	ENOG4108IPW	abc transporter atp-binding protein
GPY16_RS16430	ENOG4108Z6Z	Transcriptional regulator
GPY16_RS16460	ENOG4105EM2	membrane
GPY16_RS16470	ENOG4108Z5K	methylglyoxal synthase
GPY16_RS16475	ENOG4108SV3	Tmao reductase system periplasmic protein tort
GPY16_RS16480	ENOG4105BZU	Histidine kinase
GPY16_RS16500	ENOG4105E6M	Sulphatase-modifying factor protein
GPY16_RS16505	ENOG4105CUW	cytochrome C-TYPE protein
GPY16_RS16530	ENOG4105C1J	atp-dependent rna helicase
GPY16_RS16555	ENOG4105BZU	Histidine kinase
GPY16_RS16565	ENOG4107S17	Phosphate-binding protein
GPY16_RS16585	ENOG4105C1J	atp-dependent rna helicase
GPY16_RS16590	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
GPY16_RS16595	ENOG4105ENH	Sulfatase
GPY16_RS16600	ENOG41064T2	transcriptional regulator, lysR family
GPY16_RS16605	ENOG4105ENH	Sulfatase
GPY16_RS16610	ENOG4105C4X	radical SAM domain protein
GPY16_RS16615	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
GPY16_RS16645	ENOG41064T2	transcriptional regulator, lysR family
GPY16_RS16660	ENOG4105C4X	radical SAM domain protein
GPY16_RS16670	ENOG4105F2V	VRR-NUC domain-containing protein
GPY16_RS16690	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
GPY16_RS16745	ENOG4105BZ1	(ABC) transporter
GPY16_RS16760	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
GPY16_RS16810	ENOG4105DM4	PTS System
GPY16_RS16815	ENOG4105DE4	1-phosphofructokinase
GPY16_RS16820	ENOG4105DTZ	bifunctional PTS system fructose-specific transporter subunit IIA HPr protein
GPY16_RS16825	ENOG4107B7Y	DNA-binding transcriptional regulator FruR
GPY16_RS16850	ENOG4105CA9	Pyruvate kinase
GPY16_RS16855	ENOG4105CXY	transporter
GPY16_RS16860	ENOG4106JDA	Phosphoglycerate transport regulatory protein PGTC
GPY16_RS16870	ENOG4107TXD	phosphoglycerate transport system transcriptional regulatory protein pgta
GPY16_RS16875	ENOG4108I6A	alcohol dehydrogenase
GPY16_RS16880	ENOG4105CF7	AraC family transcriptional regulator
GPY16_RS16895	ENOG4105CKU	formyltetrahydrofolate synthetase
GPY16_RS16900	ENOG4107RE1	Inosine-guanosine kinase
GPY16_RS16915	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
GPY16_RS16920	ENOG4107XGZ	Hydrolase
GPY16_RS16925	ENOG4108NVR	Methyl-accepting chemotaxis
GPY16_RS16930	ENOG4108ZYK	Acyl carrier protein phosphodiesterase
GPY16_RS16935	ENOG4105C1J	atp-dependent rna helicase
GPY16_RS16950	ENOG4105DS1	cytochrome b561
GPY16_RS16955	ENOG4108YYC	ycei family
GPY16_RS16965	ENOG4105DUM	transcriptional regulator, lysR family
GPY16_RS16970	ENOG4108UQ5	membrane protein YcdZ
GPY16_RS16975	ENOG4105CPB	ATP-dependent endonuclease of the OLD family
GPY16_RS16980	ENOG4105CGH	5'-nucleotidase
GPY16_RS16995	ENOG4108I0N	Transporter, RarD family, DMT superfamily protein
GPY16_RS17015	ENOG4108M0H	Extracellular lipase
GPY16_RS17020	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
GPY16_RS17035	ENOG4105KA0	thioesterase Superfamily protein
GPY16_RS17045	ENOG4105KNR	Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity)
GPY16_RS17055	ENOG4105CG3	alpha amylase, catalytic region
GPY16_RS17060	ENOG4105C5Q	Transcriptional regulator
GPY16_RS17080	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
GPY16_RS17110	ENOG4108I0Y	(ABC) transporter
GPY16_RS17115	ENOG4105CV6	ABC transporter, permease
GPY16_RS17120	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
GPY16_RS17125	ENOG4107R7A	Allophanate hydrolase subunit 2
GPY16_RS17130	ENOG4105P4J	Allophanate hydrolase, subunit 1
GPY16_RS17145	ENOG4105BZU	Histidine kinase
GPY16_RS17155	ENOG4105CWB	LysR family transcriptional Regulator
GPY16_RS17160	ENOG4105CD5	CoA-binding domain protein
GPY16_RS17180	ENOG4108ZJT	translation initiation factor, Sui1
GPY16_RS17200	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
GPY16_RS17210	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
GPY16_RS17215	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
GPY16_RS17230	ENOG4105BZU	Histidine kinase
GPY16_RS17240	ENOG4108KXV	response regulator
GPY16_RS17250	ENOG4108ZT1	Transcriptional regulator
GPY16_RS17255	ENOG4108KTG	Membrane protein, drug metabolite transporter
GPY16_RS17260	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
GPY16_RS17265	ENOG4105E0C	molybdate abc transporter
GPY16_RS17270	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
GPY16_RS17275	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
GPY16_RS17290	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
GPY16_RS17295	ENOG4105CGF	Aromatic amino acid aminotransferase
GPY16_RS17300	ENOG4108N3W	hemolysin secretion protein
GPY16_RS17305	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
GPY16_RS17310	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
GPY16_RS17370	ENOG4105K63	Thioredoxin
GPY16_RS17380	ENOG4105ECQ	AraC Family Transcriptional Regulator
GPY16_RS17385	ENOG4107QI1	Mate efflux family protein
GPY16_RS17390	ENOG4105VXR	cytoplasmic protein
GPY16_RS17400	ENOG4105C8Q	Methyl-accepting chemotaxis
GPY16_RS17405	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
GPY16_RS17420	ENOG4109015	Biopolymer transport protein exbD tolR
GPY16_RS17460	ENOG4105WZK	nitrite reductase NADPH small subunit
GPY16_RS17465	ENOG4107QZF	nitrite reductase NADPH large subunit
GPY16_RS17470	ENOG4108NVR	Methyl-accepting chemotaxis
GPY16_RS17495	ENOG4105BZU	Histidine kinase
GPY16_RS17500	ENOG4105BZU	Histidine kinase
GPY16_RS17505	ENOG4107Z5C	methylesterase
GPY16_RS17520	ENOG41088SP	formiminoglutamate hydrolase
GPY16_RS17525	ENOG4105C1J	atp-dependent rna helicase
GPY16_RS17535	ENOG4105CKI	cobalamin synthesis protein
GPY16_RS17545	ENOG4105BZU	Histidine kinase
GPY16_RS17560	ENOG4107QZF	nitrite reductase NADPH large subunit
GPY16_RS17565	ENOG4105D7T	ABC transporter
GPY16_RS17570	ENOG4105DG7	nitrate ABC transporter
GPY16_RS17595	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
GPY16_RS17615	ENOG4105C8Q	Methyl-accepting chemotaxis
GPY16_RS17620	ENOG4105C8Q	Methyl-accepting chemotaxis
GPY16_RS17635	ENOG4105CXY	transporter
GPY16_RS17640	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
GPY16_RS17655	ENOG4108VAU	general secretion pathway protein G
GPY16_RS17660	ENOG4105CEE	C4-dicarboxylate transporter
GPY16_RS17665	ENOG4108V0P	LemA family
GPY16_RS17670	ENOG4105D0M	Protease HtpX homolog
GPY16_RS17715	ENOG4107TV1	YD repeat protein
GPY16_RS17740	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
GPY16_RS17785	ENOG4108ZF3	Phosphatase
GPY16_RS17800	ENOG4106VK6	Flagellar motor protein
GPY16_RS17820	ENOG4105D9P	serine threonine protein kinase
GPY16_RS17840	ENOG4105VRT	cytoplasmic protein
GPY16_RS17855	ENOG4105BZU	Histidine kinase
GPY16_RS17860	ENOG41090A4	Pterin carbinolamine dehydratase
GPY16_RS17865	ENOG4105MIR	Phenylalanine 4-monooxygenase
GPY16_RS17870	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
GPY16_RS17875	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
GPY16_RS17880	ENOG4105EGI	Transcriptional regulator
GPY16_RS17895	ENOG4108556	Isoprenoid biosynthesis protein with amidotransferase-like domain
GPY16_RS17905	ENOG4105BZU	Histidine kinase
GPY16_RS17910	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
GPY16_RS17920	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
GPY16_RS17930	ENOG4105CPP	Dehydrogenase, E1 component
GPY16_RS17935	ENOG4107QSN	dihydrolipoamide acetyltransferase
GPY16_RS17940	ENOG4105C10	Electron transfer flavoprotein
GPY16_RS17945	ENOG4105BZJ	Electron transfer flavoprotein
GPY16_RS17950	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
GPY16_RS17955	ENOG4108NVR	Methyl-accepting chemotaxis
GPY16_RS17960	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
GPY16_RS17965	ENOG4105EUK	rtx toxin RtxA
GPY16_RS17970	ENOG4108RC6	RTX toxin
GPY16_RS18015	ENOG4105CHR	reductase
GPY16_RS18020	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
GPY16_RS18025	ENOG4105E39	Enoyl-CoA hydratase
GPY16_RS18030	ENOG4105E39	Enoyl-CoA hydratase
GPY16_RS18040	ENOG4105C26	Dehydrogenase
GPY16_RS18045	ENOG4105CHU	acetyl-coa acetyltransferase
GPY16_RS18050	ENOG4107SWG	transcriptional regulator MERR family
GPY16_RS18055	ENOG4105C1G	acyl-Coa dehydrogenase
GPY16_RS18060	ENOG4107QX3	carboxylase
GPY16_RS18065	ENOG4108IPT	Naphthoate synthase
GPY16_RS18070	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
GPY16_RS18075	ENOG4105D3R	alkyl hydroperoxide reductase
GPY16_RS18080	ENOG4108JU3	Alkyl hydroperoxide reductase
GPY16_RS18085	ENOG4105VEQ	Cold shock protein
GPY16_RS18100	ENOG4108WUH	Transcriptional regulator, TetR family
GPY16_RS18105	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
GPY16_RS18120	ENOG4108YAB	Invasion protein
GPY16_RS18130	ENOG4105CXY	transporter
GPY16_RS18135	ENOG4108KX4	response regulator
GPY16_RS18140	ENOG4105BZU	Histidine kinase
GPY16_RS18145	ENOG4105CXY	transporter
GPY16_RS18150	ENOG4105EIP	mannose-6-phosphate isomerase
GPY16_RS18160	ENOG4105BZU	Histidine kinase
GPY16_RS18175	ENOG4105VEQ	Cold shock protein
GPY16_RS18205	ENOG4108V1T	peptidylprolyl cis-trans isomerase
GPY16_RS18210	ENOG4107VXZ	Hydrolase
GPY16_RS18215	ENOG4108N3W	hemolysin secretion protein
GPY16_RS18230	ENOG4107YWA	deoxycytidylate deaminase
GPY16_RS18245	ENOG4107RGM	aldo keto reductase
GPY16_RS18260	ENOG4105CMQ	Chloride channel
GPY16_RS18270	ENOG4105C5A	transporter
GPY16_RS18275	ENOG4105EUJ	GTP cyclohydrolase i
GPY16_RS18280	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
GPY16_RS18285	ENOG4105D06	uba thif-type nad fad binding protein
GPY16_RS18295	ENOG4105KHC	sulfurtransferase
GPY16_RS18300	ENOG4105BZU	Histidine kinase
GPY16_RS18320	ENOG4105CV1	Transketolase (EC 2.2.1.1)
GPY16_RS18330	ENOG4105BZU	Histidine kinase
GPY16_RS18335	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
GPY16_RS18340	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
GPY16_RS18355	ENOG4107TQK	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
GPY16_RS18375	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
GPY16_RS18380	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
GPY16_RS18385	ENOG4105BZ9	Cytochrome C oxidase, subunit I
GPY16_RS18430	ENOG4105K56	Transcriptional regulator
GPY16_RS18435	ENOG4108ZHJ	Organic hydroperoxide resistance protein
GPY16_RS18445	ENOG4105N2G	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GPY16_RS18455	ENOG4105BZU	Histidine kinase
GPY16_RS18460	ENOG4108SXK	Transporter Drug Metabolite Exporter family
GPY16_RS18465	ENOG4105VW4	glutaredoxin 3
GPY16_RS18475	ENOG4105E5M	Multidrug resistance protein D
GPY16_RS18480	ENOG4105CR8	Transcriptional regulator
GPY16_RS18490	ENOG4105M4H	endoribonuclease L-psp
GPY16_RS18500	ENOG4105E2D	ec 3.2.1.52
GPY16_RS18505	ENOG4108IA2	Sodium pantothenate symporter
GPY16_RS18525	ENOG4105CHC	glucokinase (EC 2.7.1.2)
GPY16_RS18535	ENOG4105CJ1	ABC, transporter
GPY16_RS18540	ENOG4107QWP	ABC-2 type transporter
GPY16_RS18545	ENOG4105EP9	oxidoreductase
GPY16_RS18565	ENOG410834F	Transcriptional regulator
GPY16_RS18580	ENOG4105C1J	atp-dependent rna helicase
GPY16_RS18625	ENOG4105NXH	GreA GreB family elongation factor
GPY16_RS18660	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
GPY16_RS18670	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
GPY16_RS18690	ENOG4105WH1	Two component transcriptional regulator luxr family
GPY16_RS18695	ENOG4105BZU	Histidine kinase
GPY16_RS18730	ENOG4108MX5	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses (By similarity)
GPY16_RS18740	ENOG4105QEK	Transcriptional regulator
GPY16_RS18750	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
GPY16_RS18755	ENOG41069H7	transport system small permease component
GPY16_RS18760	ENOG4108ERU	trap dicarboxylate transporter subunit DctP
GPY16_RS18765	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
GPY16_RS18775	ENOG4105CE4	GlcNAc 6-P deacetylase
GPY16_RS18785	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
GPY16_RS18795	ENOG4105CHU	acetyl-coa acetyltransferase
GPY16_RS18805	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
GPY16_RS18810	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
GPY16_RS18830	ENOG4105EW9	transcriptional regulator AsnC family
GPY16_RS18845	ENOG4105BZU	Histidine kinase
GPY16_RS18850	ENOG4108QGH	periplasmic
GPY16_RS18860	ENOG41082IR	Excinuclease ABC C subunit domain protein
GPY16_RS18875	ENOG41090HJ	UPF0265 protein
GPY16_RS18885	ENOG4105BZU	Histidine kinase
GPY16_RS18910	ENOG4105DUM	transcriptional regulator, lysR family
GPY16_RS18915	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
GPY16_RS18935	ENOG4105EW9	transcriptional regulator AsnC family
GPY16_RS18940	ENOG4105DVH	amino acid
GPY16_RS18960	ENOG4105E0F	Histidine kinase
GPY16_RS18965	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
GPY16_RS18990	ENOG4105CJW	magnesium transporter
GPY16_RS18995	ENOG41063ZK	Transcriptional Regulator AraC Family
GPY16_RS19000	ENOG4105DQW	permease for cytosine purines, uracil, thiamine, allantoin
GPY16_RS19005	ENOG4105DZC	cytosine deaminase
GPY16_RS19010	ENOG4105DAN	ATP-dependent protease
GPY16_RS19020	ENOG4108JQ5	ABC transporter
GPY16_RS19030	ENOG4105CC0	LysR family Transcriptional regulator
GPY16_RS19035	ENOG4105DAA	L-lactate
GPY16_RS19045	ENOG4107QR9	Iron-sulfur cluster binding protein
GPY16_RS19050	ENOG4108ZZK	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity)
GPY16_RS19070	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
GPY16_RS19110	ENOG4105CK1	PTS System
GPY16_RS19125	ENOG4107EII	Lipoprotein involved with copper homeostasis and adhesion
GPY16_RS19130	ENOG4105E5Z	arginine transporter ATP-binding subunit
GPY16_RS19135	ENOG4106PMH	Extracellular solute-binding protein family 3
GPY16_RS19140	ENOG4105GBT	ABC transporter
GPY16_RS19145	ENOG4105DMR	ABC, transporter
GPY16_RS19160	ENOG4105BZU	Histidine kinase
GPY16_RS19165	ENOG4108PC0	lipolytic protein G-D-S-L family
GPY16_RS19175	ENOG4108N3W	hemolysin secretion protein
GPY16_RS19180	ENOG4105E89	ABC transporter
GPY16_RS19195	ENOG4108TSE	Transferase
GPY16_RS19215	ENOG4105X17	23-dihydro-2,3-dihydroxybenzoate dehydrogenase
GPY16_RS19220	ENOG4105E4F	Isochorismate synthase
GPY16_RS19225	ENOG4108IQC	2,3-dihydroxybenzoate-AMP ligase
GPY16_RS19230	ENOG4105Q26	Siderophore-interacting protein
GPY16_RS19235	ENOG4105WQI	isochorismatase
GPY16_RS19245	ENOG4108IQC	2,3-dihydroxybenzoate-AMP ligase
GPY16_RS19260	ENOG4107RBR	Receptor
GPY16_RS19270	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
GPY16_RS19275	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
GPY16_RS19300	ENOG4108IJF	Heavy metal efflux pump, CzcA
GPY16_RS19315	ENOG4105C0F	tryptophanase EC 4.1.99.1
GPY16_RS19320	ENOG4105CIC	tryptophan-specific transport protein
GPY16_RS19325	ENOG4105C5H	ABC transporter
GPY16_RS19340	ENOG4105ETE	Transcriptional regulator (LacI family
GPY16_RS19345	ENOG4108X7Y	Mannitol-specific cryptic phosphotransferase enzyme iia
GPY16_RS19370	ENOG4105C37	(CBS) domain
GPY16_RS19375	ENOG4105C26	Dehydrogenase
GPY16_RS19380	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
GPY16_RS19385	ENOG4105BZU	Histidine kinase
GPY16_RS19390	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
GPY16_RS19395	ENOG4108RXX	maleylacetoacetate isomerase
GPY16_RS19400	ENOG4105EGI	Transcriptional regulator
GPY16_RS19405	ENOG4107TIF	Phenazine biosynthesis protein, PhzF family
GPY16_RS19410	ENOG4108S01	response regulator
GPY16_RS19420	ENOG4105D9R	oxidoreductase
GPY16_RS19445	ENOG4105EUZ	Beta-lactamase domain protein
GPY16_RS19455	ENOG4107F9Y	LysR family transcriptional regulator
GPY16_RS19465	ENOG4105DUM	transcriptional regulator, lysR family
GPY16_RS19480	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
GPY16_RS19490	ENOG4105Y49	secretion protein, HlyD family
GPY16_RS19510	ENOG4105DIJ	Phosphoethanolamine transferase
GPY16_RS19560	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
GPY16_RS19565	ENOG4108P2H	Inner membrane protein YjiG
GPY16_RS19570	ENOG41074DU	domain protein
GPY16_RS19580	ENOG4107T9C	Alpha amylase catalytic region
GPY16_RS19585	ENOG4105CAZ	oligogalacturonide lyase
GPY16_RS19590	ENOG4107QN1	sodium solute
GPY16_RS19600	ENOG4108QGT	oligogalacturonate-specific porin
GPY16_RS19605	ENOG4105CK7	Sodium proline symporter
GPY16_RS19620	ENOG4108UHU	Aldolase
GPY16_RS19625	ENOG4107SS6	2-dehydro-3-deoxygluconokinase
GPY16_RS19640	ENOG4108ESY	Metal dependent phosphohydrolase
GPY16_RS19650	ENOG4105M5J	Cupin 2, conserved barrel domain protein
GPY16_RS19655	ENOG4105P66	Membrane
GPY16_RS19660	ENOG4105CHR	reductase
GPY16_RS19690	ENOG4105DGM	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
GPY16_RS19705	ENOG4105D64	Mechanosensitive ion channel
GPY16_RS19730	ENOG4105BZU	Histidine kinase
GPY16_RS19735	ENOG4105M6F	mutator MutT protein
GPY16_RS19740	ENOG4108V1U	phospholipid-binding protein
GPY16_RS19745	ENOG4108UQN	AraC family transcriptional regulator
GPY16_RS19750	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
GPY16_RS19755	ENOG4108Z4X	TRANSCRIPTIONal
GPY16_RS19765	ENOG4105CI1	PTS System
GPY16_RS19770	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
GPY16_RS19775	ENOG4105GR3	Histidine kinase
GPY16_RS19785	ENOG4107TSX	ABC branched chain amino acid family transporter periplasmic ligand binding protein
GPY16_RS19795	ENOG4105I4A	GCN5-related N-acetyltransferase
GPY16_RS19800	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
GPY16_RS19815	ENOG4105VYW	UPF0251 protein
GPY16_RS19825	ENOG4105CA0	peroxidase
GPY16_RS19830	ENOG4105RA2	Membrane
GPY16_RS19840	ENOG41075H3	AraC family transcriptional regulator
GPY16_RS19845	ENOG4105E5M	Multidrug resistance protein D
GPY16_RS19865	ENOG4108Q67	UPF0319 protein
GPY16_RS19875	ENOG4105DP0	ferredoxin-NADP reductase
GPY16_RS19885	ENOG4108PZW	LysR family Transcriptional regulator
GPY16_RS19895	ENOG4108RCM	Nitroreductase
GPY16_RS19910	ENOG4105C1J	atp-dependent rna helicase
GPY16_RS19945	ENOG4108M3J	Dehydrogenase
GPY16_RS19955	ENOG4107W31	Pentapeptide repeat protein
GPY16_RS19965	ENOG4108NVR	Methyl-accepting chemotaxis
GPY16_RS19970	ENOG4105BZU	Histidine kinase
GPY16_RS19975	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
GPY16_RS19985	ENOG4105D5U	fad dependent oxidoreductase
GPY16_RS20000	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GPY16_RS20005	ENOG4105CQZ	Histidine kinase
GPY16_RS20015	ENOG4105EUZ	Beta-lactamase domain protein
GPY16_RS20030	ENOG4105GR3	Histidine kinase
GPY16_RS20035	ENOG4105JQN	Transcriptional regulator
GPY16_RS20040	ENOG4105J12	Multidrug resistance protein mdtN
GPY16_RS20050	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
GPY16_RS20065	ENOG4106TD9	Diguanylate cyclase
GPY16_RS20075	ENOG4105N14	lysine exporter protein LysE YggA
GPY16_RS20090	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
GPY16_RS20095	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
GPY16_RS20100	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
GPY16_RS20130	ENOG4105E0A	ABC, transporter
GPY16_RS20135	ENOG4108HUF	Transporter
GPY16_RS20140	ENOG4105S6R	Iron-hydroxamate transporter permease subunit
GPY16_RS20155	ENOG4105D2N	Aldolase
GPY16_RS20160	ENOG4105CE4	GlcNAc 6-P deacetylase
GPY16_RS20165	ENOG4108YTN	IIa component
GPY16_RS20170	ENOG4105F3R	pts system mannose fructose sorbose family iid
GPY16_RS20180	ENOG4108RG5	PTS system N-acetylgalactosamine-specific transporter subunit IIB
GPY16_RS20185	ENOG4105E70	isomerase
GPY16_RS20190	ENOG4105C6Q	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
GPY16_RS20195	ENOG410804X	Transcriptional regulator
GPY16_RS20200	ENOG4105E98	transcriptional regulator DeoR family
GPY16_RS20205	ENOG4108RNG	Permease of the drug metabolite transporter
GPY16_RS20225	ENOG4105BZU	Histidine kinase
GPY16_RS20230	ENOG4105BZU	Histidine kinase
GPY16_RS20235	ENOG4105BZU	Histidine kinase
GPY16_RS20240	ENOG4105BZU	Histidine kinase
GPY16_RS20245	ENOG41064T2	transcriptional regulator, lysR family
GPY16_RS20250	ENOG4105EUZ	Beta-lactamase domain protein
GPY16_RS20275	ENOG4105E0X	reductase
GPY16_RS20280	ENOG4107U7B	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
GPY16_RS20300	ENOG4105C8Q	Methyl-accepting chemotaxis
GPY16_RS20315	ENOG4105VW4	glutaredoxin 3
GPY16_RS20335	ENOG4105ETT	transcriptional Regulator, LysR family
GPY16_RS20340	ENOG4105F8D	glycoside hydrolase family 4
GPY16_RS20360	ENOG4108RPX	mosc domain containing protein
GPY16_RS20375	ENOG41063TF	transcriptional regulator (AraC
GPY16_RS20380	ENOG4108W2Y	isochorismatase
GPY16_RS20385	ENOG4105C1J	atp-dependent rna helicase
GPY16_RS20390	ENOG4105CHZ	Catalyzes the dehydration of D-mannonate (By similarity)
GPY16_RS20395	ENOG4105C6F	GntR Family Transcriptional Regulator
GPY16_RS20400	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
GPY16_RS20405	ENOG4105XDZ	Tripartite ATP-independent periplasmic transporter
GPY16_RS20410	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
GPY16_RS20415	ENOG4105DEI	Mannitol dehydrogenase
GPY16_RS20420	ENOG4105D2H	Uronic isomerase
GPY16_RS20425	ENOG4107SS6	2-dehydro-3-deoxygluconokinase
GPY16_RS20430	ENOG4108UHU	Aldolase
GPY16_RS20435	ENOG4105P66	Membrane
GPY16_RS20445	ENOG4105CHR	reductase
GPY16_RS20450	ENOG4105F27	Major Facilitator
GPY16_RS20460	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
GPY16_RS20480	ENOG4105N0V	mono-oxygenase ydhR
GPY16_RS20485	ENOG4105CR8	Transcriptional regulator
GPY16_RS20525	ENOG4108K4B	hydrolase
GPY16_RS20535	ENOG41064BZ	L-xylulose 5-phosphate 3-epimerase
GPY16_RS20550	ENOG4105BZ1	(ABC) transporter
GPY16_RS20555	ENOG4106AM8	polysaccharide lyase family 8
GPY16_RS20560	ENOG4105CT8	Phosphorylase
GPY16_RS20570	ENOG4105CHR	reductase
GPY16_RS20575	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
GPY16_RS20580	ENOG4105CMR	udp-glucose 4-epimerase
GPY16_RS20585	ENOG4105CHH	sulfate transporter
GPY16_RS20605	ENOG4108NVR	Methyl-accepting chemotaxis
GPY16_RS20610	ENOG4108JQ6	ABC transporter
GPY16_RS20615	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
GPY16_RS20635	ENOG4105CBG	Sulfatase
GPY16_RS20640	ENOG4105C4X	radical SAM domain protein
GPY16_RS20645	ENOG4105CBG	Sulfatase
GPY16_RS20650	ENOG41061MV	Arylsulfatase
GPY16_RS20655	ENOG4106AM8	polysaccharide lyase family 8
GPY16_RS20665	ENOG4105EW9	transcriptional regulator AsnC family
GPY16_RS20675	ENOG4105CK7	Sodium proline symporter
GPY16_RS20685	ENOG4105C26	Dehydrogenase
GPY16_RS20700	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
GPY16_RS20705	ENOG4105CQZ	Histidine kinase
GPY16_RS20715	ENOG4107QZV	Type I secretion membrane fusion protein
GPY16_RS20730	ENOG4108JJA	ABC, transporter
GPY16_RS20740	ENOG4105CEE	C4-dicarboxylate transporter
GPY16_RS20745	ENOG4105DYB	Isoaspartyl dipeptidase
GPY16_RS20760	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
GPY16_RS20765	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
GPY16_RS20775	ENOG4108UW5	maltose o-acetyltransferase
GPY16_RS20795	ENOG4108PSC	Represses the expression of the murPQ operon involved in the uptake and degradation of N-acetylmuramic acid (MurNAc). Binds to two adjacent inverted repeats within the operator region. MurNAc 6-phosphate, the substrate of MurQ, is the specific inducer that weakens binding of MurR to the operator (By similarity)
GPY16_RS20800	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GPY16_RS20805	ENOG4108EKE	The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in N-acetylmuramic acid (MurNAc) transport, yielding cytoplasmic MurNAc-6-P. Is also able to take up anhydro-N-acetylmuramic acid (anhMurNAc), but cannot phosphorylate the carbon 6, probably because of the 1,6-anhydro ring (By similarity)
GPY16_RS20820	ENOG4105CVJ	phosphoglycerate mutase
GPY16_RS20825	ENOG4105KXC	Collagenase
GPY16_RS20840	ENOG4107WZZ	SMC domain protein
GPY16_RS20865	ENOG4105BZU	Histidine kinase
GPY16_RS20875	ENOG4105C8Q	Methyl-accepting chemotaxis
GPY16_RS20890	ENOG4105BZU	Histidine kinase
GPY16_RS20895	ENOG4105C8Q	Methyl-accepting chemotaxis
GPY16_RS20900	ENOG4108V3W	Chemotaxis protein, CheW
GPY16_RS20905	ENOG4108V3W	Chemotaxis protein, CheW
GPY16_RS20910	ENOG4105CBS	Chea signal transduction histidine kinase
GPY16_RS20915	ENOG4108VYJ	response regulator receiver protein
GPY16_RS20925	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
GPY16_RS20950	ENOG4108JQ7	(ABC) transporter
GPY16_RS20975	ENOG4105BZU	Histidine kinase
GPY16_RS21000	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
GPY16_RS21005	ENOG4105D60	lipoprotein releasing system transmembrane protein
GPY16_RS21020	ENOG4108HRK	Histidine kinase
GPY16_RS21025	ENOG4108VAC	response regulator
GPY16_RS21030	ENOG4105C8Q	Methyl-accepting chemotaxis
GPY16_RS21040	ENOG4105D6U	Sodium Glutamate Symporter
GPY16_RS21045	ENOG4105D6U	Sodium Glutamate Symporter
GPY16_RS21055	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
GPY16_RS21090	ENOG4105D03	DNA-3-methyladenine glycosylase II
GPY16_RS21095	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
GPY16_RS21115	ENOG4105DN9	Na H antiporter
GPY16_RS21125	ENOG4108IG5	Transcriptional regulator
GPY16_RS21145	ENOG4105NBK	UPF0345 protein
GPY16_RS21150	ENOG4105EUB	pirin domain protein
GPY16_RS21160	ENOG4108K0B	C-di-gmp phosphodiesterase
GPY16_RS21190	ENOG4105BZU	Histidine kinase
GPY16_RS21200	ENOG4108KDD	Involved in the transport of maltose and maltodextrins (By similarity)
GPY16_RS21205	ENOG4107W52	maltose operon periplasmic protein
GPY16_RS21215	ENOG4107FKK	extracellular solute-binding protein family 1
GPY16_RS21245	ENOG4105CXN	decarboxylase
GPY16_RS21250	ENOG4105D5Q	Arginine ornithine antiporter
GPY16_RS21255	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
GPY16_RS21270	ENOG41080T7	secreted protein
GPY16_RS21300	ENOG41061ZR	Transcriptional regulator
GPY16_RS21305	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
GPY16_RS21310	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
GPY16_RS21330	ENOG4105EW9	transcriptional regulator AsnC family
GPY16_RS21340	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
GPY16_RS21360	ENOG41083B3	HAD-superfamily subfamily IB hydrolase
GPY16_RS21365	ENOG4105C8Q	Methyl-accepting chemotaxis
GPY16_RS21380	ENOG4105C26	Dehydrogenase
GPY16_RS21385	ENOG4105CYM	Glutathione S-transferase
GPY16_RS21390	ENOG4105DHT	Metal Dependent Phosphohydrolase
GPY16_RS21400	ENOG4107RAN	Peptidase, M16
GPY16_RS21410	ENOG4105DUM	transcriptional regulator, lysR family
GPY16_RS21420	ENOG4105DHQ	Histidine kinase
GPY16_RS21425	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
GPY16_RS21450	ENOG4105BZU	Histidine kinase
GPY16_RS21465	ENOG41060NJ	transcriptional regulator
GPY16_RS21480	ENOG4105DRS	transport system, permease
GPY16_RS21495	ENOG4105ETE	Transcriptional regulator (LacI family
GPY16_RS21505	ENOG4105DEF	Extracellular solute-binding protein, family 5
GPY16_RS21515	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
GPY16_RS21520	ENOG4105C3U	ABC transporter
GPY16_RS21525	ENOG4108JQ7	(ABC) transporter
GPY16_RS21535	ENOG41060NJ	transcriptional regulator
GPY16_RS21550	ENOG4108KDD	Involved in the transport of maltose and maltodextrins (By similarity)
GPY16_RS21555	ENOG4105ECQ	AraC Family Transcriptional Regulator
GPY16_RS21565	ENOG4105UQX	Mate efflux family protein
GPY16_RS21575	ENOG4105EFX	secretion protein, HlyD family
GPY16_RS21600	ENOG4105D3G	Pseudouridine synthase
GPY16_RS21605	ENOG4105BZU	Histidine kinase
GPY16_RS21625	ENOG41060NJ	transcriptional regulator
GPY16_RS21630	ENOG4107SDZ	Galactoside transport system permease protein mglC
GPY16_RS21655	ENOG4105CT4	transporter
GPY16_RS21665	ENOG4108Z4U	Ferredoxin
GPY16_RS21670	ENOG4105DZ0	fad dependent oxidoreductase
GPY16_RS21675	ENOG4105FDP	GntR family transcriptional regulator
GPY16_RS21680	ENOG4105DM4	PTS System
GPY16_RS21685	ENOG4105C8I	hydrolase, family 38
GPY16_RS21690	ENOG4105BZW	Glycerate kinase
GPY16_RS21695	ENOG4105EIP	mannose-6-phosphate isomerase
GPY16_RS21705	ENOG4105HFT	AraC family transcriptional regulator
GPY16_RS21750	ENOG4105EIP	mannose-6-phosphate isomerase
GPY16_RS21760	ENOG4106R3P	AraC family transcriptional regulator
GPY16_RS21770	ENOG4108YRF	PTS System
GPY16_RS21775	ENOG4105DM4	PTS System
GPY16_RS21780	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
GPY16_RS21790	ENOG4105DM4	PTS System
GPY16_RS21795	ENOG4105DM4	PTS System
GPY16_RS21810	ENOG4108IEG	Formate dehydrogenase Alpha subunit
GPY16_RS21820	ENOG4107P2S	Transcriptional regulator
GPY16_RS21825	ENOG4105CI1	PTS System
GPY16_RS21830	ENOG4105C87	Aminotransferase class I and II
GPY16_RS21835	ENOG4105EIP	mannose-6-phosphate isomerase
GPY16_RS21840	ENOG4107U5R	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
GPY16_RS21845	ENOG4105DUM	transcriptional regulator, lysR family
GPY16_RS21850	ENOG4105KXC	Collagenase
GPY16_RS21875	ENOG4106Z1T	Nicotinamide Mononucleotide Transporter
GPY16_RS21880	ENOG4108I5U	Uridine phosphorylase
GPY16_RS21895	ENOG4105ETT	transcriptional Regulator, LysR family
GPY16_RS21900	ENOG4107Z6X	Transcriptional regulator
GPY16_RS21920	ENOG4105CDH	Citrulline--aspartate ligase
GPY16_RS21925	ENOG4105EXG	Transcriptional regulator
GPY16_RS21930	ENOG4105CK2	sodium dicarboxylate symporter
GPY16_RS21960	ENOG4105EXG	Transcriptional regulator
GPY16_RS21980	ENOG4105E2B	Taurine dioxygenase
GPY16_RS22010	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
GPY16_RS22020	ENOG4105BZU	Histidine kinase
GPY16_RS22035	ENOG4108K8S	endonuclease I
GPY16_RS22050	ENOG4105E0M	Sulfatase
GPY16_RS22055	ENOG4105DIJ	Phosphoethanolamine transferase
GPY16_RS22060	ENOG41080IJ	Diacylglycerol kinase
GPY16_RS22065	ENOG4105JJR	Histidine kinase
GPY16_RS22070	ENOG4107EXC	regulatoR
GPY16_RS22080	ENOG4105JQN	Transcriptional regulator
GPY16_RS22085	ENOG4105EMU	Dehydrogenase
GPY16_RS22090	ENOG4105EXG	Transcriptional regulator
GPY16_RS22110	ENOG4108Z33	Thiol disulfide Interchange Protein
GPY16_RS22115	ENOG4107SJ9	decarboxylase
GPY16_RS22120	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
GPY16_RS22130	ENOG410667J	hydrolase
GPY16_RS22155	ENOG4108TEM	pseudouridine methyltransferase
GPY16_RS22205	ENOG4108YYI	Protein of unknown function (DUF2810)
GPY16_RS22215	ENOG4105S8Q	sugar efflux transporter
GPY16_RS22230	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
GPY16_RS22235	ENOG4107RUE	extracellular solute-binding protein family 1
GPY16_RS22240	ENOG4105D05	Receptor
GPY16_RS22250	ENOG4105BZU	Histidine kinase
GPY16_RS22275	ENOG4105DHT	Metal Dependent Phosphohydrolase
GPY16_RS22295	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
GPY16_RS22320	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
GPY16_RS22325	ENOG4105EXG	Transcriptional regulator
GPY16_RS22330	ENOG4105E5W	Transporter
GPY16_RS22340	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
GPY16_RS22345	ENOG4105KUU	lipolytic protein G-D-S-L family
GPY16_RS22350	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
GPY16_RS22355	ENOG4105CPQ	Dehydrogenase