locus-tag	class	description
EPB55_RS00010	COG1278	Cold shock
EPB55_RS00025	COG0584	glycerophosphoryl diester phosphodiesterase
EPB55_RS00030	COG1349	DNA-binding transcription factor activity
EPB55_RS00035	COG3842	ATPase activity
EPB55_RS00040	COG0395	ABC-type sugar transport system, permease component
EPB55_RS00045	COG1175	transmembrane transport
EPB55_RS00050	COG1653	transport
EPB55_RS00065	COG0730	response to heat
EPB55_RS00075	COG2197	response regulator
EPB55_RS00135	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EPB55_RS00140	COG0372	Belongs to the citrate synthase family
EPB55_RS00145	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EPB55_RS00150	COG2828	Protein conserved in bacteria
EPB55_RS00180	COG0561	phosphatase activity
EPB55_RS00185	COG0602	queuosine metabolic process
EPB55_RS00190	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EPB55_RS00195	COG3706	GGDEF domain
EPB55_RS00250	COG1254	Belongs to the acylphosphatase family
EPB55_RS00255	COG2920	part of a sulfur-relay system
EPB55_RS00265	COG0670	Belongs to the BI1 family
EPB55_RS00270	COG1126	abc transporter atp-binding protein
EPB55_RS00275	COG0765	amino acid transport
EPB55_RS00280	COG4597	amino acid ABC transporter
EPB55_RS00285	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EPB55_RS00295	COG0437	4 iron, 4 sulfur cluster binding
EPB55_RS00300	COG0348	domain, Protein
EPB55_RS00305	COG0204	Acyl-transferase
EPB55_RS00310	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
EPB55_RS00325	COG1115	amino acid carrier protein
EPB55_RS00350	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EPB55_RS00365	COG3290	protein histidine kinase activity
EPB55_RS00370	COG4565	transcriptional regulatory protein
EPB55_RS00375	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EPB55_RS00380	COG0363	glucosamine-6-phosphate deaminase activity
EPB55_RS00385	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EPB55_RS00420	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EPB55_RS00430	COG0438	transferase activity, transferring glycosyl groups
EPB55_RS00475	COG2204	response regulator
EPB55_RS00505	COG1366	Belongs to the anti-sigma-factor antagonist family
EPB55_RS00510	COG1793	dna ligase
EPB55_RS00525	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EPB55_RS00540	COG2996	Protein conserved in bacteria
EPB55_RS00545	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
EPB55_RS00545	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EPB55_RS00550	COG3008	intermembrane lipid transfer
EPB55_RS00555	COG2995	paraquat-inducible protein a
EPB55_RS00560	COG1132	(ABC) transporter
EPB55_RS00565	COG1956	GAF domain-containing protein
EPB55_RS00570	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
EPB55_RS00585	COG0308	aminopeptidase N
EPB55_RS00595	COG2902	Dehydrogenase
EPB55_RS00610	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EPB55_RS00610	COG0116	Belongs to the methyltransferase superfamily
EPB55_RS00620	COG0488	(ABC) transporter
EPB55_RS00635	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EPB55_RS00640	COG1067	ATP-dependent peptidase activity
EPB55_RS00645	COG3120	sequence-specific DNA binding
EPB55_RS00750	COG2205	protein histidine kinase activity
EPB55_RS00750	COG0784	Response regulator, receiver
EPB55_RS00765	COG3278	Belongs to the heme-copper respiratory oxidase family
EPB55_RS00780	COG2010	Cytochrome c
EPB55_RS00790	COG2217	Heavy metal translocating P-type atpase
EPB55_RS00805	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EPB55_RS00810	COG0589	response to stress
EPB55_RS00820	COG3385	transposase activity
EPB55_RS00830	COG2992	FlgJ-related protein
EPB55_RS00840	COG3842	ATPase activity
EPB55_RS00845	COG1176	ABC-type spermidine putrescine transport system, permease component I
EPB55_RS00850	COG1177	transmembrane transport
EPB55_RS00860	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EPB55_RS00870	COG0004	ammonium transporteR
EPB55_RS00905	COG0437	4 iron, 4 sulfur cluster binding
EPB55_RS00910	COG3383	formate dehydrogenase (NAD+) activity
EPB55_RS00910	COG0243	molybdopterin cofactor binding
EPB55_RS00940	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EPB55_RS00950	COG0488	(ABC) transporter
EPB55_RS00965	COG3852	Histidine kinase
EPB55_RS00970	COG2204	response regulator
EPB55_RS00980	COG4662	Binding-protein-dependent transport system inner membrane component
EPB55_RS00985	COG3842	ATPase activity
EPB55_RS00995	COG0303	'Molybdopterin
EPB55_RS01005	COG1940	carbohydrate kinase activity
EPB55_RS01010	COG3148	PFAM DTW domain containing protein
EPB55_RS01020	COG0840	transmembrane signaling receptor activity
EPB55_RS01025	COG0791	NLP P60 protein
EPB55_RS01035	COG3706	GGDEF domain
EPB55_RS01055	COG0307	riboflavin synthase, alpha
EPB55_RS01060	COG0534	Mate efflux family protein
EPB55_RS01115	COG4115	mRNA cleavage
EPB55_RS01120	COG2161	toxin-antitoxin pair type II binding
EPB55_RS01155	COG0384	phenazine biosynthesis protein PhzF
EPB55_RS01330	COG1011	Hydrolase
EPB55_RS01440	COG0251	oxidation-reduction process
EPB55_RS01465	COG0346	lactoylglutathione lyase activity
EPB55_RS01640	COG0582	viral genome integration into host DNA
EPB55_RS01730	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EPB55_RS01840	COG3738	Protein conserved in bacteria
EPB55_RS01985	COG3738	Protein conserved in bacteria
EPB55_RS02430	COG0625	glutathione transferase activity
EPB55_RS02480	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EPB55_RS02655	COG0456	acetyltransferase
EPB55_RS02710	COG0384	phenazine biosynthesis protein PhzF
EPB55_RS02725	COG0625	glutathione transferase activity
EPB55_RS02765	COG0384	phenazine biosynthesis protein PhzF
EPB55_RS02930	COG2026	Addiction module toxin, RelE StbE family
EPB55_RS02960	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EPB55_RS02995	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EPB55_RS03015	COG4326	sporulation control protein
EPB55_RS03025	COG1228	amidohydrolase
EPB55_RS03030	COG0010	Belongs to the arginase family
EPB55_RS03050	COG5640	endopeptidase activity
EPB55_RS03055	COG2020	methyltransferase activity
EPB55_RS03060	COG0277	FAD linked oxidase domain protein
EPB55_RS03060	COG0247	lactate metabolic process
EPB55_RS03075	COG2885	chlorophyll binding
EPB55_RS03090	COG0295	cytidine deaminase activity
EPB55_RS03095	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
EPB55_RS03100	COG0500	methyltransferase
EPB55_RS03110	COG0776	regulation of translation
EPB55_RS03130	COG0072	phenylalanine-tRNA ligase activity
EPB55_RS03130	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EPB55_RS03135	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EPB55_RS03200	COG1166	arginine decarboxylase activity
EPB55_RS03205	COG0010	Belongs to the arginase family
EPB55_RS03210	COG0840	transmembrane signaling receptor activity
EPB55_RS03225	COG2814	Major facilitator Superfamily
EPB55_RS03240	COG3279	Response regulator of the LytR AlgR family
EPB55_RS03250	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
EPB55_RS03275	COG1643	Atp-dependent helicase
EPB55_RS03285	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EPB55_RS03325	COG2894	cell division
EPB55_RS03335	COG4964	Belongs to the GSP D family
EPB55_RS03365	COG3713	MltA-interacting MipA family protein
EPB55_RS03385	COG3706	GGDEF domain
EPB55_RS03395	COG0443	Heat shock 70 kDa protein
EPB55_RS03400	COG0443	Heat shock 70 kDa protein
EPB55_RS03425	COG2165	general secretion pathway protein
EPB55_RS03440	COG0297	glycogen (starch) synthase activity
EPB55_RS03440	COG0438	transferase activity, transferring glycosyl groups
EPB55_RS03445	COG0438	transferase activity, transferring glycosyl groups
EPB55_RS03470	COG1596	polysaccharide export
EPB55_RS03485	COG1115	amino acid carrier protein
EPB55_RS03490	COG1132	(ABC) transporter
EPB55_RS03495	COG1132	(ABC) transporter
EPB55_RS03510	COG0783	Belongs to the Dps family
EPB55_RS03525	COG0814	amino acid
EPB55_RS03530	COG1597	lipid kinase activity
EPB55_RS03540	COG4667	esterase of the alpha-beta hydrolase superfamily
EPB55_RS03545	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
EPB55_RS03560	COG0583	DNA-binding transcription factor activity
EPB55_RS03565	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EPB55_RS03570	COG1328	CTP reductase activity
EPB55_RS03575	COG5001	Diguanylate cyclase
EPB55_RS03575	COG3300	MHYT domain
EPB55_RS03590	COG2199	diguanylate cyclase activity
EPB55_RS03590	COG2200	EAL domain
EPB55_RS03595	COG3706	GGDEF domain
EPB55_RS03605	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EPB55_RS03605	COG4191	Histidine kinase
EPB55_RS03610	COG0471	metal ion transport
EPB55_RS03625	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EPB55_RS03630	COG3283	Transcriptional regulator of aromatic amino acids metabolism
EPB55_RS03635	COG3768	UPF0283 membrane protein
EPB55_RS03640	COG3106	COG3106 Predicted ATPase
EPB55_RS03655	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EPB55_RS03660	COG0784	Response regulator, receiver
EPB55_RS03660	COG2205	protein histidine kinase activity
EPB55_RS03670	COG0494	nUDIX hydrolase
EPB55_RS03675	COG0814	amino acid
EPB55_RS03680	COG1760	l-serine dehydratase
EPB55_RS03685	COG2200	EAL domain
EPB55_RS03695	COG0720	synthase
EPB55_RS03700	COG0840	transmembrane signaling receptor activity
EPB55_RS03705	COG0017	Asparaginyl-tRNA synthetase
EPB55_RS03715	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EPB55_RS03730	COG3437	response regulator, receiver
EPB55_RS03730	COG2770	Histidine kinase
EPB55_RS03735	COG1448	Aminotransferase
EPB55_RS03755	COG0840	transmembrane signaling receptor activity
EPB55_RS03760	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EPB55_RS03765	COG1846	Transcriptional regulator
EPB55_RS03790	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
EPB55_RS03805	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EPB55_RS03810	COG3108	Peptidase M15
EPB55_RS03815	COG2989	Protein conserved in bacteria
EPB55_RS03845	COG2186	Transcriptional regulator
EPB55_RS03850	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EPB55_RS03860	COG3012	SEC-C Motif Domain Protein
EPB55_RS03860	COG3318	Belongs to the UPF0149 family
EPB55_RS03875	COG0366	Alpha amylase catalytic
EPB55_RS03885	COG4120	Belongs to the binding-protein-dependent transport system permease family
EPB55_RS03895	COG3092	negative regulation of chromosome organization
EPB55_RS03900	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EPB55_RS03905	COG0857	belongs to the CobB CobQ family
EPB55_RS03905	COG0280	phosphate acetyltransferase
EPB55_RS03915	COG0583	DNA-binding transcription factor activity
EPB55_RS03940	COG1032	radical SAM domain protein
EPB55_RS03960	COG2207	Transcriptional regulator
EPB55_RS03975	COG0861	Integral membrane protein TerC family
EPB55_RS03980	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EPB55_RS03985	COG0840	transmembrane signaling receptor activity
EPB55_RS03990	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EPB55_RS04005	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EPB55_RS04105	COG1609	Transcriptional regulator
EPB55_RS04105	COG2207	Transcriptional regulator
EPB55_RS04165	COG0840	transmembrane signaling receptor activity
EPB55_RS04200	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
EPB55_RS04225	COG2003	Belongs to the UPF0758 family
EPB55_RS04240	COG0328	RNA-DNA hybrid ribonuclease activity
EPB55_RS04280	COG0582	viral genome integration into host DNA
EPB55_RS04295	COG0784	Response regulator, receiver
EPB55_RS04295	COG2205	protein histidine kinase activity
EPB55_RS04305	COG0754	glutathionylspermidine amidase activity
EPB55_RS04315	COG3766	membrane
EPB55_RS04325	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EPB55_RS04330	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
EPB55_RS04335	COG2885	chlorophyll binding
EPB55_RS04340	COG0823	Involved in the tonB-independent uptake of proteins
EPB55_RS04355	COG0811	peptide transport
EPB55_RS04360	COG0824	Thioesterase
EPB55_RS04370	COG4890	Cyd operon protein YbgT
EPB55_RS04375	COG1294	oxidase, subunit
EPB55_RS04380	COG1271	oxidase subunit
EPB55_RS04385	COG2255	four-way junction helicase activity
EPB55_RS04390	COG0632	four-way junction helicase activity
EPB55_RS04395	COG0840	transmembrane signaling receptor activity
EPB55_RS04415	COG4106	trans-aconitate 2-methyltransferase activity
EPB55_RS04420	COG0500	methyltransferase
EPB55_RS04425	COG4067	protein conserved in archaea
EPB55_RS04425	COG0189	ligase activity
EPB55_RS04455	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
EPB55_RS04460	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
EPB55_RS04465	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
EPB55_RS04470	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EPB55_RS04475	COG1434	Gram-negative-bacterium-type cell wall biogenesis
EPB55_RS04480	COG0745	RESPONSE REGULATOR receiver
EPB55_RS04490	COG1609	Transcriptional regulator
EPB55_RS04495	COG3070	regulator of competence-specific genes
EPB55_RS04520	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EPB55_RS04525	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EPB55_RS04550	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
EPB55_RS04555	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EPB55_RS04560	COG0542	response to heat
EPB55_RS04565	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
EPB55_RS04570	COG1278	Cold shock
EPB55_RS04590	COG1199	ATP-dependent helicase activity
EPB55_RS04600	COG3923	Primosomal replication protein n
EPB55_RS04610	COG0840	transmembrane signaling receptor activity
EPB55_RS04615	COG0708	Exodeoxyribonuclease III
EPB55_RS04655	COG1882	Formate acetyltransferase
EPB55_RS04670	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EPB55_RS04680	COG3013	Belongs to the UPF0304 family
EPB55_RS04685	COG2766	serine protein kinase
EPB55_RS04690	COG2718	Belongs to the UPF0229 family
EPB55_RS04695	COG2719	SpoVR family
EPB55_RS04700	COG2199	diguanylate cyclase activity
EPB55_RS04705	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
EPB55_RS04710	COG2835	tetraacyldisaccharide 4'-kinase activity
EPB55_RS04715	COG1663	tetraacyldisaccharide 4'-kinase activity
EPB55_RS04725	COG2333	competence protein COMEC
EPB55_RS04725	COG0658	competence protein
EPB55_RS04735	COG4591	ABC-type transport system involved in lipoprotein release permease component
EPB55_RS04740	COG1136	(ABC) transporter
EPB55_RS04745	COG4591	ABC-type transport system involved in lipoprotein release permease component
EPB55_RS04755	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EPB55_RS04770	COG1252	NADH dehydrogenase
EPB55_RS04800	COG0537	adenosine 5'-monophosphoramidase activity
EPB55_RS04825	COG0617	tRNA 3'-terminal CCA addition
EPB55_RS04825	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EPB55_RS04825	COG0517	IMP dehydrogenase activity
EPB55_RS04830	COG3706	GGDEF domain
EPB55_RS04835	COG1982	Orn Lys Arg decarboxylase major
EPB55_RS04840	COG0531	amino acid
EPB55_RS04845	COG3710	Transcriptional regulator
EPB55_RS04865	COG2203	Gaf domain
EPB55_RS04865	COG2199	diguanylate cyclase activity
EPB55_RS04870	COG2239	Acts as a magnesium transporter
EPB55_RS04880	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EPB55_RS04885	COG2226	methyltransferase
EPB55_RS04900	COG1785	Belongs to the alkaline phosphatase family
EPB55_RS04910	COG0346	lactoylglutathione lyase activity
EPB55_RS04920	COG2983	Belongs to the UPF0260 family
EPB55_RS04935	COG0745	RESPONSE REGULATOR receiver
EPB55_RS04940	COG2205	protein histidine kinase activity
EPB55_RS04955	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EPB55_RS04960	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EPB55_RS04970	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EPB55_RS04975	COG2832	Protein of unknown function (DUF454)
EPB55_RS04985	COG0745	RESPONSE REGULATOR receiver
EPB55_RS04990	COG0583	DNA-binding transcription factor activity
EPB55_RS04995	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EPB55_RS05000	COG1286	toxin biosynthetic process
EPB55_RS05005	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
EPB55_RS05010	COG0285	dihydrofolate synthase activity
EPB55_RS05015	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EPB55_RS05020	COG0101	tRNA pseudouridine synthase activity
EPB55_RS05030	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EPB55_RS05040	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EPB55_RS05045	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
EPB55_RS05045	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EPB55_RS05055	COG3101	peptidyl-lysine hydroxylation
EPB55_RS05060	COG2860	membrane
EPB55_RS05065	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EPB55_RS05070	COG2890	protein-(glutamine-N5) methyltransferase activity
EPB55_RS05075	COG2840	Smr protein MutS2
EPB55_RS05080	COG2062	phosphohistidine phosphatase, SixA
EPB55_RS05085	COG1025	Belongs to the peptidase M16 family
EPB55_RS05090	COG1250	3-hydroxyacyl-CoA dehydrogenase
EPB55_RS05090	COG1024	Enoyl-CoA hydratase
EPB55_RS05095	COG0183	Belongs to the thiolase family
EPB55_RS05110	COG2067	long-chain fatty acid transport protein
EPB55_RS05120	COG2853	Lipoprotein
EPB55_RS05130	COG3088	subunit of a heme lyase
EPB55_RS05130	COG4235	cytochrome complex assembly
EPB55_RS05135	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EPB55_RS05140	COG1138	Cytochrome C-type biogenesis protein
EPB55_RS05145	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
EPB55_RS05150	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EPB55_RS05155	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EPB55_RS05160	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EPB55_RS05165	COG4133	protoheme IX ABC transporter activity
EPB55_RS05175	COG0835	chemotaxis
EPB55_RS05185	COG1192	Involved in chromosome partitioning
EPB55_RS05190	COG2201	protein-glutamate methylesterase activity
EPB55_RS05195	COG2198	Histidine kinase
EPB55_RS05195	COG0784	Response regulator, receiver
EPB55_RS05195	COG0643	Histidine kinase
EPB55_RS05200	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
EPB55_RS05235	COG1684	flagellar biosynthetic protein fliR
EPB55_RS05240	COG1987	bacterial-type flagellum assembly
EPB55_RS05290	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EPB55_RS05300	COG1677	Flagellar hook-basal body complex protein FliE
EPB55_RS05320	COG1516	flagellar protein fliS
EPB55_RS05330	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
EPB55_RS05335	COG1334	flagellar protein FlaG
EPB55_RS05340	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EPB55_RS05345	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EPB55_RS05350	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EPB55_RS05355	COG2837	iron assimilation
EPB55_RS05380	COG1393	Belongs to the ArsC family
EPB55_RS05400	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
EPB55_RS05405	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EPB55_RS05410	COG2716	regulation of RNA biosynthetic process
EPB55_RS05415	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EPB55_RS05430	COG4783	chaperone-mediated protein folding
EPB55_RS05435	COG1393	Belongs to the ArsC family
EPB55_RS05455	COG2233	PERMEase
EPB55_RS05460	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EPB55_RS05465	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EPB55_RS05470	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EPB55_RS05475	COG0121	glutamine amidotransferase
EPB55_RS05485	COG1960	acyl-CoA dehydrogenase activity
EPB55_RS05520	COG2249	NAD(P)H dehydrogenase (quinone) activity
EPB55_RS05535	COG0328	RNA-DNA hybrid ribonuclease activity
EPB55_RS05540	COG2226	methyltransferase
EPB55_RS05545	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EPB55_RS05550	COG0741	lytic transglycosylase activity
EPB55_RS05550	COG1388	LysM domain
EPB55_RS05560	COG3021	interspecies interaction between organisms
EPB55_RS05565	COG0347	Belongs to the P(II) protein family
EPB55_RS05580	COG0825	malonyl-CoA metabolic process
EPB55_RS05585	COG0587	DNA-directed DNA polymerase activity
EPB55_RS05590	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EPB55_RS05595	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EPB55_RS05600	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EPB55_RS05605	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EPB55_RS05610	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EPB55_RS05615	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
EPB55_RS05620	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EPB55_RS05625	COG0750	zinc metalloprotease
EPB55_RS05630	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
EPB55_RS05635	COG0575	Belongs to the CDS family
EPB55_RS05640	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EPB55_RS05645	COG0233	cytoplasmic translational termination
EPB55_RS05650	COG0528	UMP kinase activity
EPB55_RS05655	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EPB55_RS05660	COG0052	Belongs to the universal ribosomal protein uS2 family
EPB55_RS05665	COG0024	Methionine aminopeptidase
EPB55_RS05670	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
EPB55_RS05685	COG3098	single-species biofilm formation
EPB55_RS05725	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EPB55_RS05745	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
EPB55_RS05755	COG0254	rRNA binding
EPB55_RS05760	COG1720	tRNA m6t6A37 methyltransferase activity
EPB55_RS05785	COG0733	neurotransmitter:sodium symporter activity
EPB55_RS05800	COG0514	ATP-dependent DNA helicase (RecQ)
EPB55_RS05805	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EPB55_RS05820	COG1477	protein flavinylation
EPB55_RS05825	COG2871	sodium ion transport
EPB55_RS05830	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
EPB55_RS05840	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
EPB55_RS05845	COG1805	sodium ion transport
EPB55_RS05850	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
EPB55_RS05855	COG0271	Belongs to the BolA IbaG family
EPB55_RS05860	COG2813	Specifically methylates the guanine in position
EPB55_RS05875	COG2211	Major facilitator Superfamily
EPB55_RS05885	COG1595	DNA-templated transcription, initiation
EPB55_RS05900	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EPB55_RS05905	COG0693	protein deglycase activity
EPB55_RS05910	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EPB55_RS05915	COG2166	iron-sulfur cluster assembly
EPB55_RS05920	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EPB55_RS05925	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
EPB55_RS05945	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EPB55_RS05950	COG1074	ATP-dependent DNA helicase activity
EPB55_RS05960	COG3083	sulfuric ester hydrolase activity
EPB55_RS05975	COG3141	response to X-ray
EPB55_RS05980	COG2171	N-acyltransferase activity
EPB55_RS05985	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EPB55_RS05990	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EPB55_RS05995	COG1349	DNA-binding transcription factor activity
EPB55_RS06000	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EPB55_RS06015	COG0569	domain protein
EPB55_RS06015	COG0189	ligase activity
EPB55_RS06035	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EPB55_RS06045	COG0840	transmembrane signaling receptor activity
EPB55_RS06050	COG2211	Major facilitator Superfamily
EPB55_RS06060	COG1609	Transcriptional regulator
EPB55_RS06065	COG2017	converts alpha-aldose to the beta-anomer
EPB55_RS06080	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EPB55_RS06085	COG1609	Transcriptional regulator
EPB55_RS06095	COG3250	beta-galactosidase activity
EPB55_RS06100	COG2731	YhcH YjgK YiaL family protein
EPB55_RS06105	COG0531	amino acid
EPB55_RS06110	COG0531	amino acid
EPB55_RS06115	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
EPB55_RS06115	COG3408	Glycogen debranching enzyme
EPB55_RS06125	COG0583	DNA-binding transcription factor activity
EPB55_RS06130	COG2059	Chromate
EPB55_RS06180	COG4964	Belongs to the GSP D family
EPB55_RS06215	COG1022	Amp-dependent synthetase and ligase
EPB55_RS06225	COG0583	DNA-binding transcription factor activity
EPB55_RS06230	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EPB55_RS06250	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EPB55_RS06260	COG0560	Phosphoserine phosphatase
EPB55_RS06270	COG0813	purine-nucleoside phosphorylase activity
EPB55_RS06275	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EPB55_RS06280	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
EPB55_RS06285	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EPB55_RS06290	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EPB55_RS06295	COG0084	hydrolase, TatD family'
EPB55_RS06305	COG3706	GGDEF domain
EPB55_RS06315	COG0456	acetyltransferase
EPB55_RS06325	COG3153	acetyltransferase
EPB55_RS06330	COG3154	lipid carrier protein
EPB55_RS06340	COG0826	peptidase U32
EPB55_RS06345	COG0826	peptidase U32
EPB55_RS06350	COG0534	Mate efflux family protein
EPB55_RS06365	COG1185	polyribonucleotide nucleotidyltransferase activity
EPB55_RS06385	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EPB55_RS06390	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EPB55_RS06395	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EPB55_RS06405	COG0195	Participates in both transcription termination and antitermination
EPB55_RS06410	COG0779	Required for maturation of 30S ribosomal subunits
EPB55_RS06425	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EPB55_RS06430	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EPB55_RS06435	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EPB55_RS06440	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EPB55_RS06445	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
EPB55_RS06450	COG1534	Rna-binding protein
EPB55_RS06460	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
EPB55_RS06465	COG2027	D-alanyl-D-alanine carboxypeptidase
EPB55_RS06470	COG2832	Protein of unknown function (DUF454)
EPB55_RS06475	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EPB55_RS06480	COG0739	heme binding
EPB55_RS06505	COG0628	permease
EPB55_RS06515	COG2205	protein histidine kinase activity
EPB55_RS06515	COG0784	Response regulator, receiver
EPB55_RS06520	COG0747	negative chemotaxis
EPB55_RS06525	COG0601	transmembrane transport
EPB55_RS06530	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EPB55_RS06535	COG0444	Belongs to the ABC transporter superfamily
EPB55_RS06540	COG4608	Belongs to the ABC transporter superfamily
EPB55_RS06550	COG2971	BadF BadG BcrA BcrD
EPB55_RS06565	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EPB55_RS06570	COG3842	ATPase activity
EPB55_RS06580	COG1840	ABC-type Fe3 transport system, periplasmic component
EPB55_RS06585	COG0004	ammonium transporteR
EPB55_RS06590	COG0347	Belongs to the P(II) protein family
EPB55_RS06595	COG3112	Uncharacterised protein family (UPF0231)
EPB55_RS06600	COG3835	regulator
EPB55_RS06605	COG2610	gluconate transmembrane transporter activity
EPB55_RS06610	COG1929	Belongs to the glycerate kinase type-1 family
EPB55_RS06615	COG1049	propionate catabolic process, 2-methylcitrate cycle
EPB55_RS06620	COG1752	Esterase of the alpha-beta hydrolase superfamily
EPB55_RS06625	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EPB55_RS06630	COG1643	Atp-dependent helicase
EPB55_RS06635	COG1489	DNA binding
EPB55_RS06640	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EPB55_RS06645	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EPB55_RS06655	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EPB55_RS06660	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EPB55_RS06670	COG0842	Transport permease protein
EPB55_RS06675	COG1131	(ABC) transporter
EPB55_RS06680	COG0659	secondary active sulfate transmembrane transporter activity
EPB55_RS06685	COG0288	reversible hydration of carbon dioxide
EPB55_RS06700	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EPB55_RS06705	COG0508	dehydrogenase complex catalyzes the overall conversion of
EPB55_RS06710	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
EPB55_RS06715	COG2186	Transcriptional regulator
EPB55_RS06720	COG3023	N-Acetylmuramoyl-L-alanine amidase
EPB55_RS06735	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EPB55_RS06740	COG1459	type II secretion system
EPB55_RS06760	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
EPB55_RS06765	COG0335	large ribosomal subunit rRNA binding
EPB55_RS06770	COG0336	Belongs to the RNA methyltransferase TrmD family
EPB55_RS06775	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EPB55_RS06780	COG0228	four-way junction DNA binding
EPB55_RS06785	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EPB55_RS06790	COG4137	Cytochrome C assembly protein
EPB55_RS06795	COG4536	flavin adenine dinucleotide binding
EPB55_RS06800	COG1854	S-ribosylhomocysteine lyase activity
EPB55_RS06810	COG2918	glutathione biosynthetic process
EPB55_RS06815	COG0612	Peptidase, M16
EPB55_RS06820	COG1238	metal cluster binding
EPB55_RS06830	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
EPB55_RS06835	COG5016	pyruvate
EPB55_RS06835	COG0511	ligase activity, forming carbon-carbon bonds
EPB55_RS06840	COG3630	sodium ion export across plasma membrane
EPB55_RS06885	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
EPB55_RS06890	COG0527	aspartate kinase activity
EPB55_RS06895	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EPB55_RS06900	COG2137	regulation of response to DNA damage stimulus
EPB55_RS06905	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EPB55_RS06915	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EPB55_RS06920	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EPB55_RS06925	COG4942	peptidase
EPB55_RS06925	COG1388	LysM domain
EPB55_RS06930	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EPB55_RS06945	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
EPB55_RS06950	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EPB55_RS06955	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
EPB55_RS06960	COG0148	phosphopyruvate hydratase activity
EPB55_RS06965	COG0504	CTP synthase activity
EPB55_RS06970	COG3956	TIGRFAM MazG family protein
EPB55_RS06975	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EPB55_RS06980	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EPB55_RS06985	COG4999	Histidine kinase
EPB55_RS06985	COG3850	Histidine kinase
EPB55_RS06985	COG3437	response regulator, receiver
EPB55_RS06985	COG2205	protein histidine kinase activity
EPB55_RS07010	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
EPB55_RS07015	COG1381	Involved in DNA repair and RecF pathway recombination
EPB55_RS07020	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EPB55_RS07025	COG0571	ribonuclease III activity
EPB55_RS07035	COG0481	GTPase activity
EPB55_RS07040	COG3086	response to oxidative stress
EPB55_RS07055	COG1595	DNA-templated transcription, initiation
EPB55_RS07060	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EPB55_RS07090	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EPB55_RS07095	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EPB55_RS07100	COG3079	Belongs to the UPF0149 family
EPB55_RS07105	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
EPB55_RS07115	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EPB55_RS07125	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EPB55_RS07140	COG1279	arginine transmembrane transporter activity
EPB55_RS07145	COG0668	transmembrane transport
EPB55_RS07150	COG0191	fructose-bisphosphate aldolase activity
EPB55_RS07155	COG0126	phosphoglycerate kinase activity
EPB55_RS07170	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EPB55_RS07175	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EPB55_RS07190	COG2356	endonuclease I
EPB55_RS07200	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EPB55_RS07210	COG1678	Uncharacterized ACR, COG1678
EPB55_RS07215	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EPB55_RS07230	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EPB55_RS07235	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EPB55_RS07240	COG0762	integral membrane protein
EPB55_RS07255	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EPB55_RS07260	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EPB55_RS07270	COG2066	Belongs to the glutaminase family
EPB55_RS07275	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EPB55_RS07285	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
EPB55_RS07290	COG0741	lytic transglycosylase activity
EPB55_RS07400	COG3437	response regulator, receiver
EPB55_RS07410	COG1609	Transcriptional regulator
EPB55_RS07420	COG1486	melibiose metabolic process
EPB55_RS07425	COG1447	Phosphotransferase system cellobiose-specific component IIA
EPB55_RS07435	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EPB55_RS07440	COG0726	polysaccharide deacetylase
EPB55_RS07455	COG0795	lipopolysaccharide-transporting ATPase activity
EPB55_RS07460	COG0795	lipopolysaccharide-transporting ATPase activity
EPB55_RS07465	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EPB55_RS07470	COG2927	DNA polymerase III (CHI subunit)
EPB55_RS07475	COG0525	valine-tRNA ligase activity
EPB55_RS07485	COG0456	acetyltransferase
EPB55_RS07515	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
EPB55_RS07520	COG0251	oxidation-reduction process
EPB55_RS07525	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EPB55_RS07540	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EPB55_RS07545	COG0312	modulator of DNA gyrase
EPB55_RS07550	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EPB55_RS07555	COG3164	Protein of unknown function
EPB55_RS07565	COG0424	maF-like protein
EPB55_RS07570	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
EPB55_RS07575	COG1792	Involved in formation and maintenance of cell shape
EPB55_RS07580	COG1077	Cell shape determining protein MreB Mrl
EPB55_RS07615	COG2165	general secretion pathway protein
EPB55_RS07625	COG1459	type II secretion system
EPB55_RS07630	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EPB55_RS07640	COG3267	Type II secretory pathway component ExeA
EPB55_RS07640	COG3409	Peptidoglycan-binding domain 1 protein
EPB55_RS07665	COG2200	EAL domain
EPB55_RS07665	COG2199	diguanylate cyclase activity
EPB55_RS07685	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EPB55_RS07695	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EPB55_RS07700	COG0527	aspartate kinase activity
EPB55_RS07785	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EPB55_RS07815	COG0735	belongs to the Fur family
EPB55_RS07830	COG0432	Pfam Uncharacterised protein family UPF0047
EPB55_RS07840	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EPB55_RS07855	COG0359	binds to the 23S rRNA
EPB55_RS07865	COG2965	DNA replication, synthesis of RNA primer
EPB55_RS07870	COG0360	Binds together with S18 to 16S ribosomal RNA
EPB55_RS07875	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EPB55_RS07880	COG0338	D12 class N6 adenine-specific DNA methyltransferase
EPB55_RS07895	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EPB55_RS07925	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EPB55_RS07940	COG0165	Argininosuccinate lyase
EPB55_RS07940	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
EPB55_RS07945	COG0137	argininosuccinate synthase activity
EPB55_RS07955	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EPB55_RS07960	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EPB55_RS07965	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
EPB55_RS07975	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EPB55_RS07980	COG0460	homoserine dehydrogenase
EPB55_RS07980	COG0527	aspartate kinase activity
EPB55_RS07985	COG0626	cystathionine gamma-synthase activity
EPB55_RS07990	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
EPB55_RS07995	COG0281	malic enzyme
EPB55_RS08010	COG1609	Transcriptional regulator
EPB55_RS08020	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EPB55_RS08025	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EPB55_RS08030	COG1575	Belongs to the MenA family. Type 1 subfamily
EPB55_RS08040	COG3074	FtsZ-dependent cytokinesis
EPB55_RS08045	COG1494	fructose-1,6-bisphosphatase
EPB55_RS08070	COG0149	triose-phosphate isomerase activity
EPB55_RS08075	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EPB55_RS08085	COG2906	2 iron, 2 sulfur cluster binding
EPB55_RS08095	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EPB55_RS08100	COG0049	tRNA binding
EPB55_RS08105	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EPB55_RS08110	COG2168	tRNA wobble position uridine thiolation
EPB55_RS08125	COG2964	Protein conserved in bacteria
EPB55_RS08130	COG0545	Peptidyl-prolyl cis-trans isomerase
EPB55_RS08140	COG2900	Belongs to the SlyX family
EPB55_RS08150	COG1047	Peptidyl-prolyl cis-trans
EPB55_RS08165	COG2249	NAD(P)H dehydrogenase (quinone) activity
EPB55_RS08170	COG0488	(ABC) transporter
EPB55_RS08180	COG0429	hydrolase of the alpha beta-hydrolase fold
EPB55_RS08185	COG3089	Belongs to the UPF0270 family
EPB55_RS08190	COG3954	Phosphoribulokinase
EPB55_RS08195	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EPB55_RS08205	COG1012	belongs to the aldehyde dehydrogenase family
EPB55_RS08215	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EPB55_RS08245	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EPB55_RS08250	COG0557	exoribonuclease II activity
EPB55_RS08255	COG0402	S-adenosylhomocysteine deaminase activity
EPB55_RS08260	COG1959	2 iron, 2 sulfur cluster binding
EPB55_RS08270	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
EPB55_RS08275	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EPB55_RS08280	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
EPB55_RS08285	COG0330	HflC and HflK could
EPB55_RS08290	COG0330	HflC and HflK could
EPB55_RS08295	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EPB55_RS08300	COG1923	regulation of RNA biosynthetic process
EPB55_RS08315	COG0860	N-Acetylmuramoyl-L-alanine amidase
EPB55_RS08320	COG0802	atpase or kinase
EPB55_RS08325	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EPB55_RS08385	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
EPB55_RS08390	COG1162	GTPase activity
EPB55_RS08395	COG0688	phosphatidylethanolamine metabolic process
EPB55_RS08400	COG0471	metal ion transport
EPB55_RS08410	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EPB55_RS08420	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EPB55_RS08425	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
EPB55_RS08430	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EPB55_RS08435	COG1045	serine acetyltransferase
EPB55_RS08440	COG4942	peptidase
EPB55_RS08460	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
EPB55_RS08465	COG1053	succinate dehydrogenase
EPB55_RS08470	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EPB55_RS08475	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
EPB55_RS08480	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
EPB55_RS08490	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EPB55_RS08495	COG1509	lysine 2,3-aminomutase activity
EPB55_RS08500	COG1285	pathogenesis
EPB55_RS08510	COG0459	protein refolding
EPB55_RS08515	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EPB55_RS08520	COG0534	Mate efflux family protein
EPB55_RS08525	COG0205	6-phosphofructokinase activity
EPB55_RS08535	COG3678	ATP-independent chaperone mediated protein folding
EPB55_RS08540	COG0745	RESPONSE REGULATOR receiver
EPB55_RS08545	COG2205	protein histidine kinase activity
EPB55_RS08555	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EPB55_RS08565	COG1027	Aspartate ammonia-lyase
EPB55_RS08570	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EPB55_RS08575	COG4232	protein-disulfide reductase activity
EPB55_RS08585	COG2095	MarC family integral membrane protein
EPB55_RS08595	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EPB55_RS08610	COG2205	protein histidine kinase activity
EPB55_RS08610	COG2198	Histidine kinase
EPB55_RS08610	COG0784	Response regulator, receiver
EPB55_RS08615	COG2814	Major facilitator Superfamily
EPB55_RS08630	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EPB55_RS08635	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EPB55_RS08640	COG0511	ligase activity, forming carbon-carbon bonds
EPB55_RS08645	COG0439	Biotin carboxylase
EPB55_RS08660	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
EPB55_RS08665	COG0840	transmembrane signaling receptor activity
EPB55_RS08670	COG0789	Transcriptional regulator
EPB55_RS08680	COG0138	bifunctional purine biosynthesis protein purh
EPB55_RS08700	COG1253	flavin adenine dinucleotide binding
EPB55_RS08705	COG3068	Protein conserved in bacteria
EPB55_RS08710	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EPB55_RS08715	COG1573	uracil-dna glycosylase
EPB55_RS08720	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EPB55_RS08740	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
EPB55_RS08750	COG0085	RNA polymerase activity
EPB55_RS08755	COG0222	ribosome binding
EPB55_RS08760	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EPB55_RS08765	COG0081	regulation of translation
EPB55_RS08780	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EPB55_RS08785	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EPB55_RS08820	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EPB55_RS08830	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EPB55_RS08920	COG4206	TonB-dependent receptor
EPB55_RS08940	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EPB55_RS08950	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EPB55_RS08955	COG2937	Belongs to the GPAT DAPAT family
EPB55_RS08970	COG1580	Controls the rotational direction of flagella during chemotaxis
EPB55_RS08975	COG0705	Rhomboid family
EPB55_RS08980	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EPB55_RS08990	COG2177	Part of the ABC transporter FtsEX involved in
EPB55_RS08995	COG2884	Cell division ATP-binding protein ftsE
EPB55_RS09000	COG0552	protein localization to endoplasmic reticulum
EPB55_RS09005	COG0742	ribosomal rna small subunit methyltransferase
EPB55_RS09015	COG2095	MarC family integral membrane protein
EPB55_RS09060	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EPB55_RS09065	COG0640	Transcriptional regulator
EPB55_RS09070	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
EPB55_RS09075	COG1280	lysine exporter protein (LysE YggA)
EPB55_RS09080	COG2267	carboxylic ester hydrolase activity
EPB55_RS09085	COG0561	phosphatase activity
EPB55_RS09100	COG3148	PFAM DTW domain containing protein
EPB55_RS09105	COG2200	EAL domain
EPB55_RS09105	COG3287	FIST C domain
EPB55_RS09105	COG2199	diguanylate cyclase activity
EPB55_RS09110	COG1011	Hydrolase
EPB55_RS09115	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
EPB55_RS09125	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EPB55_RS09130	COG0019	diaminopimelate decarboxylase activity
EPB55_RS09140	COG1965	Belongs to the frataxin family
EPB55_RS09145	COG3072	Adenylate cyclase
EPB55_RS09150	COG0181	hydroxymethylbilane synthase activity
EPB55_RS09160	COG2959	enzyme of heme biosynthesis
EPB55_RS09170	COG2081	HI0933 family
EPB55_RS09180	COG1528	Iron-storage protein
EPB55_RS09185	COG0589	response to stress
EPB55_RS09205	COG5001	Diguanylate cyclase
EPB55_RS09205	COG5002	protein histidine kinase activity
EPB55_RS09210	COG1522	sequence-specific DNA binding
EPB55_RS09220	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
EPB55_RS09225	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EPB55_RS09245	COG0800	Aldolase
EPB55_RS09250	COG2610	gluconate transmembrane transporter activity
EPB55_RS09255	COG3265	gluconokinase activity
EPB55_RS09260	COG0129	dihydroxy-acid dehydratase activity
EPB55_RS09265	COG1609	Transcriptional regulator
EPB55_RS09270	COG0745	RESPONSE REGULATOR receiver
EPB55_RS09280	COG0515	serine threonine protein kinase
EPB55_RS09280	COG2815	serine threonine protein kinase
EPB55_RS09315	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EPB55_RS09320	COG0601	transmembrane transport
EPB55_RS09325	COG4166	transmembrane transport
EPB55_RS09330	COG4172	Belongs to the ABC transporter superfamily
EPB55_RS09370	COG1309	transcriptional regulator
EPB55_RS09375	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EPB55_RS09380	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EPB55_RS09385	COG2960	long-chain fatty acid transporting porin activity
EPB55_RS09390	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EPB55_RS09430	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EPB55_RS09440	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EPB55_RS09445	COG0408	coproporphyrinogen oxidase activity
EPB55_RS09450	COG0009	L-threonylcarbamoyladenylate synthase
EPB55_RS09455	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EPB55_RS09465	COG0551	DNA topoisomerase type I activity
EPB55_RS09470	COG2922	Belongs to the Smg family
EPB55_RS09475	COG0758	DNA mediated transformation
EPB55_RS09485	COG0242	peptide deformylase activity
EPB55_RS09490	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EPB55_RS09495	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EPB55_RS09495	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EPB55_RS09500	COG0569	domain protein
EPB55_RS09505	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EPB55_RS09510	COG1272	protein, Hemolysin III
EPB55_RS09515	COG4326	sporulation control protein
EPB55_RS09520	COG3084	Protein conserved in bacteria
EPB55_RS09530	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EPB55_RS09535	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EPB55_RS09540	COG0204	Acyl-transferase
EPB55_RS09550	COG0606	chelatase, subunit chli
EPB55_RS09560	COG3978	acetolactate synthase activity
EPB55_RS09565	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EPB55_RS09580	COG0583	DNA-binding transcription factor activity
EPB55_RS09585	COG2814	Major facilitator Superfamily
EPB55_RS09595	COG0765	amino acid transport
EPB55_RS09605	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EPB55_RS09615	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EPB55_RS09620	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EPB55_RS09625	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EPB55_RS09630	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EPB55_RS09640	COG0356	it plays a direct role in the translocation of protons across the membrane
EPB55_RS09645	COG3312	ion transport
EPB55_RS09650	COG1475	DNA binding
EPB55_RS09655	COG1192	Involved in chromosome partitioning
EPB55_RS09660	COG0357	Ribosomal RNA small subunit methyltransferase G
EPB55_RS09665	COG0445	tRNA wobble uridine modification
EPB55_RS09670	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EPB55_RS09675	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EPB55_RS09680	COG0706	membrane insertase activity
EPB55_RS09690	COG0594	ribonuclease P activity
EPB55_RS09695	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EPB55_RS09700	COG1126	abc transporter atp-binding protein
EPB55_RS09720	COG0592	DNA-directed DNA polymerase activity
EPB55_RS09730	COG0187	DNA topoisomerase II activity
EPB55_RS09735	COG0071	Belongs to the small heat shock protein (HSP20) family
EPB55_RS09745	COG3977	Valine--pyruvate aminotransferase
EPB55_RS09760	COG0752	glycyl-tRNA synthetase alpha subunit
EPB55_RS09765	COG2119	membrane
EPB55_RS09775	COG0425	Belongs to the sulfur carrier protein TusA family
EPB55_RS09790	COG0604	alcohol dehydrogenase
EPB55_RS09795	COG0183	Belongs to the thiolase family
EPB55_RS09805	COG1739	Uncharacterized protein family UPF0029
EPB55_RS09810	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EPB55_RS09855	COG2132	Multicopper oxidase
EPB55_RS09860	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EPB55_RS09865	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EPB55_RS09870	COG0352	thiamine-phosphate diphosphorylase activity
EPB55_RS09875	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EPB55_RS09885	COG2022	thiamine diphosphate biosynthetic process
EPB55_RS09895	COG0006	proline dipeptidase activity
EPB55_RS09895	COG0006	proline dipeptidase activity
EPB55_RS09935	COG0210	DNA helicase
EPB55_RS09945	COG1280	lysine exporter protein (LysE YggA)
EPB55_RS09955	COG2962	Rard protein
EPB55_RS09960	COG0514	ATP-dependent DNA helicase (RecQ)
EPB55_RS09970	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EPB55_RS09975	COG0248	Ppx GppA phosphatase
EPB55_RS09985	COG3118	belongs to the thioredoxin family
EPB55_RS10085	COG3335	DDE superfamily endonuclease
EPB55_RS10100	COG1322	Protein conserved in bacteria
EPB55_RS10105	COG2226	methyltransferase
EPB55_RS10110	COG3165	ubiquinone biosynthetic process from chorismate
EPB55_RS10120	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EPB55_RS10125	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EPB55_RS10130	COG0805	protein transport
EPB55_RS10135	COG0084	hydrolase, TatD family'
EPB55_RS10145	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EPB55_RS10145	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EPB55_RS10165	COG3078	GTPase activator activity
EPB55_RS10180	COG5001	Diguanylate cyclase
EPB55_RS10180	COG3300	MHYT domain
EPB55_RS10185	COG2204	response regulator
EPB55_RS10190	COG3852	Histidine kinase
EPB55_RS10205	COG1217	gtp-binding protein TYPA
EPB55_RS10220	COG1295	ribonuclease BN
EPB55_RS10225	COG1490	D-aminoacyl-tRNA deacylase activity
EPB55_RS10230	COG0456	acetyltransferase
EPB55_RS10245	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EPB55_RS10250	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EPB55_RS10255	COG3031	protein transport across the cell outer membrane
EPB55_RS10265	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EPB55_RS10270	COG1459	type II secretion system
EPB55_RS10275	COG2165	general secretion pathway protein
EPB55_RS10280	COG2165	general secretion pathway protein
EPB55_RS10285	COG2165	general secretion pathway protein
EPB55_RS10290	COG4795	General secretion pathway protein
EPB55_RS10295	COG3156	type II secretion system protein K
EPB55_RS10300	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
EPB55_RS10305	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
EPB55_RS10315	COG1218	3'(2'),5'-bisphosphate nucleotidase
EPB55_RS10320	COG0494	nUDIX hydrolase
EPB55_RS10325	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EPB55_RS10325	COG0316	Belongs to the HesB IscA family
EPB55_RS10330	COG1040	competence protein
EPB55_RS10335	COG0596	Alpha beta hydrolase
EPB55_RS10345	COG2183	response to ionizing radiation
EPB55_RS10350	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EPB55_RS10365	COG2233	PERMEase
EPB55_RS10370	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EPB55_RS10375	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EPB55_RS10380	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EPB55_RS10385	COG1758	RNA polymerase activity
EPB55_RS10390	COG0194	GDP metabolic process
EPB55_RS10405	COG0848	biopolymer transport protein
EPB55_RS10410	COG0811	peptide transport
EPB55_RS10415	COG0811	peptide transport
EPB55_RS10425	COG4206	TonB-dependent receptor
EPB55_RS10430	COG4174	ABC transporter (Permease)
EPB55_RS10435	COG4239	(ABC) transporter, permease
EPB55_RS10440	COG0747	negative chemotaxis
EPB55_RS10445	COG0444	Belongs to the ABC transporter superfamily
EPB55_RS10450	COG4608	Belongs to the ABC transporter superfamily
EPB55_RS10470	COG1561	YicC-like family, N-terminal region
EPB55_RS10475	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EPB55_RS10485	COG1560	Kdo2-lipid A biosynthetic process
EPB55_RS10490	COG1309	transcriptional regulator
EPB55_RS10505	COG2003	Belongs to the UPF0758 family
EPB55_RS10510	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EPB55_RS10515	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EPB55_RS10535	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EPB55_RS10540	COG0859	PFAM glycosyl transferase family 9
EPB55_RS10545	COG0463	Glycosyl transferase, family 2
EPB55_RS10550	COG0859	PFAM glycosyl transferase family 9
EPB55_RS10555	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EPB55_RS10560	COG3642	lipopolysaccharide core region biosynthetic process
EPB55_RS10565	COG3083	sulfuric ester hydrolase activity
EPB55_RS10580	COG1086	Polysaccharide biosynthesis protein
EPB55_RS10585	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EPB55_RS10595	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EPB55_RS10600	COG0107	imidazoleglycerol-phosphate synthase activity
EPB55_RS10605	COG1083	cytidylyl-transferase
EPB55_RS10615	COG2089	acid synthase
EPB55_RS10625	COG1519	Transferase
EPB55_RS10630	COG0859	PFAM glycosyl transferase family 9
EPB55_RS10645	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EPB55_RS10665	COG1596	polysaccharide export
EPB55_RS10685	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EPB55_RS10715	COG0438	transferase activity, transferring glycosyl groups
EPB55_RS10725	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EPB55_RS10745	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
EPB55_RS10760	COG0088	Forms part of the polypeptide exit tunnel
EPB55_RS10765	COG0089	rRNA binding
EPB55_RS10770	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EPB55_RS10775	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EPB55_RS10785	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EPB55_RS10790	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EPB55_RS10795	COG0255	Belongs to the universal ribosomal protein uL29 family
EPB55_RS10800	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EPB55_RS10805	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EPB55_RS10810	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EPB55_RS10815	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EPB55_RS10820	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EPB55_RS10825	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EPB55_RS10830	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EPB55_RS10835	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EPB55_RS10840	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EPB55_RS10845	COG1841	ribosomal large subunit assembly
EPB55_RS10850	COG0200	Binds to the 23S rRNA
EPB55_RS10855	COG0201	protein transport
EPB55_RS10860	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EPB55_RS10865	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EPB55_RS10870	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EPB55_RS10875	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EPB55_RS10880	COG0202	RNA polymerase activity
EPB55_RS10885	COG0203	ribosomal protein L17
EPB55_RS10895	COG0545	Peptidyl-prolyl cis-trans isomerase
EPB55_RS10900	COG3061	Opacity-associated protein A
EPB55_RS10900	COG3266	domain, Protein
EPB55_RS10910	COG2153	protein acetylation
EPB55_RS10920	COG0737	Belongs to the 5'-nucleotidase family
EPB55_RS10925	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EPB55_RS10925	COG1648	precorrin-2 dehydrogenase activity
EPB55_RS10930	COG0175	sulfate reduction
EPB55_RS10935	COG2895	sulfate adenylyltransferase (ATP) activity
EPB55_RS10940	COG0471	metal ion transport
EPB55_RS10940	COG3273	potassium ion transport
EPB55_RS10945	COG0529	Catalyzes the synthesis of activated sulfate
EPB55_RS10965	COG0577	efflux transmembrane transporter activity
EPB55_RS10965	COG1136	(ABC) transporter
EPB55_RS10980	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
EPB55_RS10995	COG0729	surface antigen
EPB55_RS11000	COG2911	Protein conserved in bacteria
EPB55_RS11005	COG2105	PFAM AIG2 family protein
EPB55_RS11015	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EPB55_RS11020	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
EPB55_RS11025	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EPB55_RS11030	COG0163	prenyltransferase activity
EPB55_RS11035	COG4143	(ABC) transporter
EPB55_RS11045	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
EPB55_RS11050	COG3028	Belongs to the UPF0307 family
EPB55_RS11055	COG0312	modulator of DNA gyrase
EPB55_RS11060	COG2239	Acts as a magnesium transporter
EPB55_RS11065	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EPB55_RS11070	COG1660	Displays ATPase and GTPase activities
EPB55_RS11075	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EPB55_RS11080	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EPB55_RS11090	COG1137	ATPase activity
EPB55_RS11095	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
EPB55_RS11105	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
EPB55_RS11110	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
EPB55_RS11110	COG0517	IMP dehydrogenase activity
EPB55_RS11120	COG1127	ABC transporter
EPB55_RS11125	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EPB55_RS11130	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EPB55_RS11135	COG2854	intermembrane phospholipid transfer
EPB55_RS11145	COG5007	Belongs to the BolA IbaG family
EPB55_RS11150	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EPB55_RS11155	COG0204	Acyl-transferase
EPB55_RS11160	COG0589	response to stress
EPB55_RS11170	COG2358	TRAP transporter, solute receptor (TAXI family
EPB55_RS11175	COG1438	arginine binding
EPB55_RS11180	COG0039	L-malate dehydrogenase activity
EPB55_RS11185	COG0142	geranyltranstransferase activity
EPB55_RS11190	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EPB55_RS11195	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EPB55_RS11205	COG2966	Psort location CytoplasmicMembrane, score
EPB55_RS11210	COG3610	response to peptide
EPB55_RS11225	COG2967	ApaG domain
EPB55_RS11230	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EPB55_RS11235	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EPB55_RS11240	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EPB55_RS11245	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
EPB55_RS11270	COG0473	3-isopropylmalate dehydrogenase activity
EPB55_RS11275	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EPB55_RS11300	COG1022	Amp-dependent synthetase and ligase
EPB55_RS11305	COG0028	Belongs to the TPP enzyme family
EPB55_RS11310	COG0440	acetolactate synthase activity
EPB55_RS11315	COG3706	GGDEF domain
EPB55_RS11330	COG1349	DNA-binding transcription factor activity
EPB55_RS11335	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EPB55_RS11340	COG3722	fumarate hydratase activity
EPB55_RS11350	COG2213	PTS system mannitol-specific
EPB55_RS11350	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EPB55_RS11355	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
EPB55_RS11385	COG1610	YqeY-like protein
EPB55_RS11390	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EPB55_RS11395	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EPB55_RS11400	COG0596	Alpha beta hydrolase
EPB55_RS11410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EPB55_RS11415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EPB55_RS11425	COG0617	tRNA 3'-terminal CCA addition
EPB55_RS11430	COG3267	Type II secretory pathway component ExeA
EPB55_RS11430	COG3409	Peptidoglycan-binding domain 1 protein
EPB55_RS11435	COG4991	sh3 domain protein
EPB55_RS11440	COG0306	phosphate transporter
EPB55_RS11445	COG1392	Phosphate transport regulator
EPB55_RS11450	COG3025	triphosphatase activity
EPB55_RS11455	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EPB55_RS11465	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
EPB55_RS11475	COG1538	Outer membrane efflux protein
EPB55_RS11480	COG0494	nUDIX hydrolase
EPB55_RS11485	COG3151	Protein conserved in bacteria
EPB55_RS11495	COG3150	esterase
EPB55_RS11510	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EPB55_RS11515	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EPB55_RS11520	COG3105	Protein conserved in bacteria
EPB55_RS11525	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
EPB55_RS11535	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EPB55_RS11540	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EPB55_RS11545	COG0723	plastoquinol--plastocyanin reductase activity
EPB55_RS11550	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EPB55_RS11555	COG2857	Cytochrome c1
EPB55_RS11560	COG0625	glutathione transferase activity
EPB55_RS11565	COG2969	positive regulation of protein catabolic process
EPB55_RS11570	COG2823	Periplasmic or secreted lipoprotein
EPB55_RS11575	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
EPB55_RS11580	COG0792	nuclease activity
EPB55_RS11585	COG3107	peptidoglycan biosynthetic process
EPB55_RS11590	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EPB55_RS11600	COG0275	rRNA processing
EPB55_RS11605	COG3116	cell division
EPB55_RS11610	COG0768	penicillin binding
EPB55_RS11620	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EPB55_RS11630	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EPB55_RS11635	COG0772	Belongs to the SEDS family
EPB55_RS11645	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EPB55_RS11650	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EPB55_RS11655	COG0849	cell division
EPB55_RS11660	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EPB55_RS11665	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
EPB55_RS11675	COG0653	protein targeting
EPB55_RS11680	COG0494	nUDIX hydrolase
EPB55_RS11690	COG0505	Belongs to the CarA family
EPB55_RS11695	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EPB55_RS11705	COG0730	response to heat
EPB55_RS11710	COG0583	DNA-binding transcription factor activity
EPB55_RS11715	COG2860	membrane
EPB55_RS11720	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EPB55_RS11730	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EPB55_RS11740	COG0493	'glutamate synthase
EPB55_RS11745	COG0069	glutamate synthase activity
EPB55_RS11745	COG0070	glutamate synthase
EPB55_RS11745	COG0067	glutamate synthase
EPB55_RS11755	COG0070	glutamate synthase
EPB55_RS11755	COG0067	glutamate synthase
EPB55_RS11755	COG0069	glutamate synthase activity
EPB55_RS11760	COG1242	4 iron, 4 sulfur cluster binding
EPB55_RS11765	COG5001	Diguanylate cyclase
EPB55_RS11765	COG4251	negative regulation of phosphorylation
EPB55_RS11765	COG3706	GGDEF domain
EPB55_RS11765	COG2203	Gaf domain
EPB55_RS11770	COG0784	Response regulator, receiver
EPB55_RS11770	COG2198	Histidine kinase
EPB55_RS11770	COG5002	protein histidine kinase activity
EPB55_RS11780	COG0745	RESPONSE REGULATOR receiver
EPB55_RS11795	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EPB55_RS11810	COG0083	homoserine kinase activity
EPB55_RS11815	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EPB55_RS11820	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
EPB55_RS11830	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EPB55_RS11845	COG1115	amino acid carrier protein
EPB55_RS11850	COG3022	response to hydroperoxide
EPB55_RS11855	COG0513	Belongs to the DEAD box helicase family
EPB55_RS11860	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EPB55_RS11875	COG4974	Belongs to the 'phage' integrase family
EPB55_RS11880	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EPB55_RS11885	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EPB55_RS11895	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EPB55_RS11910	COG0667	Aldo Keto reductase
EPB55_RS11920	COG3066	DNA modification
EPB55_RS11925	COG0494	nUDIX hydrolase
EPB55_RS11935	COG0730	response to heat
EPB55_RS11955	COG1283	sodium-dependent phosphate transmembrane transporter activity
EPB55_RS11960	COG0583	DNA-binding transcription factor activity
EPB55_RS11965	COG0640	Transcriptional regulator
EPB55_RS11970	COG0268	Binds directly to 16S ribosomal RNA
EPB55_RS11975	COG0728	peptidoglycan biosynthetic process
EPB55_RS11980	COG0196	riboflavin kinase activity
EPB55_RS11985	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EPB55_RS11990	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EPB55_RS11995	COG1047	Peptidyl-prolyl cis-trans
EPB55_RS12000	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EPB55_RS12010	COG3275	phosphorelay sensor kinase activity
EPB55_RS12015	COG1966	Carbon starvation protein
EPB55_RS12035	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
EPB55_RS12050	COG1605	Chorismate mutase
EPB55_RS12050	COG0287	Prephenate dehydrogenase
EPB55_RS12055	COG0739	heme binding
EPB55_RS12065	COG0488	(ABC) transporter
EPB55_RS12075	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
EPB55_RS12085	COG1605	Chorismate mutase
EPB55_RS12085	COG0077	Prephenate dehydratase
EPB55_RS12090	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EPB55_RS12100	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EPB55_RS12115	COG0542	response to heat
EPB55_RS12155	COG3385	transposase activity
EPB55_RS12160	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EPB55_RS12165	COG0826	peptidase U32
EPB55_RS12175	COG0745	RESPONSE REGULATOR receiver
EPB55_RS12180	COG5002	protein histidine kinase activity
EPB55_RS12190	COG0248	Ppx GppA phosphatase
EPB55_RS12200	COG0573	inorganic phosphate transmembrane transporter activity
EPB55_RS12205	COG0581	inorganic phosphate transmembrane transporter activity
EPB55_RS12210	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EPB55_RS12215	COG0704	Plays a role in the regulation of phosphate uptake
EPB55_RS12240	COG0450	alkyl hydroperoxide reductase
EPB55_RS12245	COG0583	DNA-binding transcription factor activity
EPB55_RS12250	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EPB55_RS12260	COG0517	IMP dehydrogenase activity
EPB55_RS12270	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EPB55_RS12275	COG0343	queuine tRNA-ribosyltransferase activity
EPB55_RS12280	COG1862	Preprotein translocase
EPB55_RS12285	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EPB55_RS12290	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EPB55_RS12305	COG0483	inositol monophosphate 1-phosphatase activity
EPB55_RS12310	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
EPB55_RS12315	COG1959	2 iron, 2 sulfur cluster binding
EPB55_RS12325	COG0822	iron-sulfur transferase activity
EPB55_RS12330	COG0316	Belongs to the HesB IscA family
EPB55_RS12340	COG0443	Heat shock 70 kDa protein
EPB55_RS12345	COG0633	Ferredoxin
EPB55_RS12350	COG2975	iron-sulfur cluster assembly
EPB55_RS12355	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EPB55_RS12360	COG0105	UTP biosynthetic process
EPB55_RS12375	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EPB55_RS12380	COG0124	histidyl-tRNA synthetase
EPB55_RS12385	COG2976	Protein conserved in bacteria
EPB55_RS12390	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EPB55_RS12405	COG2199	diguanylate cyclase activity
EPB55_RS12405	COG2203	Gaf domain
EPB55_RS12420	COG0517	IMP dehydrogenase activity
EPB55_RS12420	COG0516	GMP reductase activity
EPB55_RS12425	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EPB55_RS12425	COG0519	Catalyzes the synthesis of GMP from XMP
EPB55_RS12435	COG1584	GPR1 FUN34 yaaH family protein
EPB55_RS12440	COG1115	amino acid carrier protein
EPB55_RS12445	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EPB55_RS12450	COG0583	DNA-binding transcription factor activity
EPB55_RS12465	COG3385	transposase activity
EPB55_RS12475	COG0009	L-threonylcarbamoyladenylate synthase
EPB55_RS12515	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EPB55_RS12520	COG2867	negative regulation of translational initiation
EPB55_RS12525	COG2914	Belongs to the UPF0125 (RnfH) family
EPB55_RS12530	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EPB55_RS12535	COG0497	DNA recombination
EPB55_RS12540	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EPB55_RS12545	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EPB55_RS12575	COG0443	Heat shock 70 kDa protein
EPB55_RS12580	COG0484	heat shock protein binding
EPB55_RS12590	COG4969	Belongs to the N-Me-Phe pilin family
EPB55_RS12610	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
EPB55_RS12615	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
EPB55_RS12620	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
EPB55_RS12625	COG0583	DNA-binding transcription factor activity
EPB55_RS12640	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
EPB55_RS12645	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EPB55_RS12645	COG0047	phosphoribosylformylglycinamidine synthase activity
EPB55_RS12670	COG2195	Cleaves the N-terminal amino acid of tripeptides
EPB55_RS12675	COG2252	PERMEase
EPB55_RS12680	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
EPB55_RS12685	COG1073	alpha beta
EPB55_RS12695	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EPB55_RS12705	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EPB55_RS12710	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EPB55_RS12710	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EPB55_RS12725	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
EPB55_RS12730	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EPB55_RS12735	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EPB55_RS12740	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EPB55_RS12745	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EPB55_RS12750	COG0142	geranyltranstransferase activity
EPB55_RS12755	COG1722	exodeoxyribonuclease VII activity
EPB55_RS12760	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EPB55_RS12775	COG0583	DNA-binding transcription factor activity
EPB55_RS12785	COG2363	Small membrane protein
EPB55_RS12800	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EPB55_RS12805	COG1611	Belongs to the LOG family
EPB55_RS12830	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
EPB55_RS12835	COG1464	Belongs to the NlpA lipoprotein family
EPB55_RS12840	COG2011	ABC-type metal ion transport system permease component
EPB55_RS12850	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EPB55_RS12860	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EPB55_RS12860	COG1263	PTS System
EPB55_RS12865	COG0366	Alpha amylase catalytic
EPB55_RS12875	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EPB55_RS12885	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EPB55_RS12890	COG0321	lipoyl(octanoyl) transferase activity
EPB55_RS12895	COG2921	Belongs to the UPF0250 family
EPB55_RS12900	COG1686	Belongs to the peptidase S11 family
EPB55_RS12905	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EPB55_RS12910	COG0772	Belongs to the SEDS family
EPB55_RS12915	COG0768	penicillin binding
EPB55_RS12920	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EPB55_RS12925	COG0799	negative regulation of ribosome biogenesis
EPB55_RS12930	COG1466	dna polymerase III delta subunit
EPB55_RS12935	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
EPB55_RS12945	COG2888	peptidyl-tyrosine sulfation
EPB55_RS12950	COG0815	Transfers the fatty acyl group on membrane lipoproteins
EPB55_RS12955	COG4535	Mg2 and Co2 transporter CorC
EPB55_RS12960	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EPB55_RS12965	COG1702	phosphate starvation-inducible protein PhoH
EPB55_RS12975	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EPB55_RS13060	COG0193	aminoacyl-tRNA hydrolase activity
EPB55_RS13065	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EPB55_RS13070	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EPB55_RS13080	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EPB55_RS13085	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EPB55_RS13090	COG2890	protein-(glutamine-N5) methyltransferase activity
EPB55_RS13100	COG2912	Transglutaminase-like superfamily
EPB55_RS13105	COG2877	3-deoxy-8-phosphooctulonate synthase activity
EPB55_RS13120	COG1187	pseudouridine synthase activity
EPB55_RS13125	COG2840	Smr protein MutS2
EPB55_RS13140	COG3735	TraB family
EPB55_RS13155	COG2608	mercury ion transmembrane transporter activity
EPB55_RS13155	COG2217	Heavy metal translocating P-type atpase
EPB55_RS13215	COG0784	Response regulator, receiver
EPB55_RS13215	COG0835	chemotaxis
EPB55_RS13220	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EPB55_RS13225	COG1815	bacterial-type flagellum-dependent cell motility
EPB55_RS13240	COG1749	Flagellar hook protein flgE
EPB55_RS13245	COG4787	bacterial-type flagellum-dependent cell motility
EPB55_RS13255	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
EPB55_RS13260	COG1706	bacterial-type flagellum-dependent cell motility
EPB55_RS13265	COG3951	Flagellar rod assembly protein muramidase FlgJ
EPB55_RS13265	COG1705	Flagellar rod assembly protein muramidase FlgJ
EPB55_RS13275	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EPB55_RS13280	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EPB55_RS13290	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EPB55_RS13295	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EPB55_RS13300	COG2190	(PTS) system
EPB55_RS13305	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EPB55_RS13310	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EPB55_RS13315	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EPB55_RS13320	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
EPB55_RS13325	COG3115	cell septum assembly
EPB55_RS13355	COG3118	belongs to the thioredoxin family
EPB55_RS13365	COG0300	oxidoreductase activity
EPB55_RS13370	COG1090	epimerase
EPB55_RS13395	COG0622	Phosphoesterase
EPB55_RS13415	COG3710	Transcriptional regulator
EPB55_RS13420	COG0326	Molecular chaperone. Has ATPase activity
EPB55_RS13430	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EPB55_RS13440	COG3104	oligopeptide transport
EPB55_RS13450	COG0367	asparagine synthase
EPB55_RS13455	COG4651	solute:proton antiporter activity
EPB55_RS13455	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EPB55_RS13460	COG1940	carbohydrate kinase activity
EPB55_RS13460	COG1846	Transcriptional regulator
EPB55_RS13465	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EPB55_RS13470	COG1263	PTS System
EPB55_RS13470	COG2190	(PTS) system
EPB55_RS13470	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EPB55_RS13475	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EPB55_RS13490	COG0716	FMN binding
EPB55_RS13500	COG0596	Alpha beta hydrolase
EPB55_RS13505	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
EPB55_RS13510	COG0033	Phosphoglucomutase
EPB55_RS13515	COG2964	Protein conserved in bacteria
EPB55_RS13520	COG0251	oxidation-reduction process
EPB55_RS13530	COG0446	pyridine nucleotide-disulphide oxidoreductase
EPB55_RS13540	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EPB55_RS13550	COG2009	succinate dehydrogenase
EPB55_RS13555	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
EPB55_RS13560	COG1053	succinate dehydrogenase
EPB55_RS13570	COG0567	Dehydrogenase, E1 component
EPB55_RS13575	COG0508	dehydrogenase complex catalyzes the overall conversion of
EPB55_RS13590	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EPB55_RS13595	COG1121	(ABC) transporter
EPB55_RS13600	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
EPB55_RS13610	COG1918	ferrous iron import across plasma membrane
EPB55_RS13635	COG3102	Protein conserved in bacteria
EPB55_RS13640	COG0788	formyltetrahydrofolate deformylase activity
EPB55_RS13650	COG1199	ATP-dependent helicase activity
EPB55_RS13655	COG1214	PFAM Peptidase M22, glycoprotease
EPB55_RS13670	COG0596	Alpha beta hydrolase
EPB55_RS13675	COG0318	PFAM AMP-dependent synthetase and ligase
EPB55_RS13680	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
EPB55_RS13685	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
EPB55_RS13690	COG2894	cell division
EPB55_RS13695	COG0850	regulation of cytokinetic process
EPB55_RS13705	COG2951	lytic endotransglycosylase activity
EPB55_RS13715	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EPB55_RS13725	COG0745	RESPONSE REGULATOR receiver
EPB55_RS13730	COG5002	protein histidine kinase activity
EPB55_RS13745	COG1028	Short-chain dehydrogenase reductase Sdr
EPB55_RS13755	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EPB55_RS13780	COG2986	histidine ammonia-lyase
EPB55_RS13785	COG1216	Glycosyl transferase, family 2
EPB55_RS13795	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EPB55_RS13805	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EPB55_RS13810	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EPB55_RS13870	COG1175	transmembrane transport
EPB55_RS13880	COG3842	ATPase activity
EPB55_RS13885	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EPB55_RS13890	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
EPB55_RS13895	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
EPB55_RS13905	COG2204	response regulator
EPB55_RS13910	COG4191	Histidine kinase
EPB55_RS13925	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EPB55_RS13930	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EPB55_RS13935	COG0776	regulation of translation
EPB55_RS13940	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EPB55_RS13945	COG1555	photosystem II stabilization
EPB55_RS13960	COG0232	Belongs to the dGTPase family. Type 2 subfamily
EPB55_RS13965	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
EPB55_RS13970	COG0436	Aminotransferase
EPB55_RS13975	COG1169	isochorismate synthase
EPB55_RS13990	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EPB55_RS14050	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EPB55_RS14055	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EPB55_RS14105	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EPB55_RS14110	COG1522	sequence-specific DNA binding
EPB55_RS14120	COG1946	Acyl-CoA thioesterase
EPB55_RS14125	COG3126	Type III secretion system lipoprotein chaperone (YscW)
EPB55_RS14195	COG0732	type I restriction modification DNA specificity domain
EPB55_RS14200	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EPB55_RS14300	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EPB55_RS14315	COG3139	Protein of unknown function (DUF1315)
EPB55_RS14320	COG0252	asparaginase activity
EPB55_RS14325	COG0616	signal peptide processing
EPB55_RS14330	COG1902	pentaerythritol trinitrate reductase activity
EPB55_RS14330	COG0446	pyridine nucleotide-disulphide oxidoreductase
EPB55_RS14335	COG0778	Nitroreductase
EPB55_RS14340	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EPB55_RS14345	COG0123	including yeast histone deacetylase and acetoin utilization protein
EPB55_RS14350	COG2205	protein histidine kinase activity
EPB55_RS14350	COG0784	Response regulator, receiver
EPB55_RS14360	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EPB55_RS14365	COG2731	YhcH YjgK YiaL family protein
EPB55_RS14370	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EPB55_RS14375	COG0569	domain protein
EPB55_RS14385	COG3083	sulfuric ester hydrolase activity
EPB55_RS14390	COG3082	Protein of unknown function (DUF1414)
EPB55_RS14395	COG3081	Nucleoid-associated protein
EPB55_RS14410	COG1757	Na H antiporter
EPB55_RS14415	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EPB55_RS14425	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EPB55_RS14430	COG2095	MarC family integral membrane protein
EPB55_RS14435	COG1454	alcohol dehydrogenase
EPB55_RS14435	COG1012	belongs to the aldehyde dehydrogenase family
EPB55_RS14440	COG1028	Short-chain dehydrogenase reductase Sdr
EPB55_RS14455	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EPB55_RS14465	COG2056	Na+-H+ antiporter family
EPB55_RS14470	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EPB55_RS14475	COG2885	chlorophyll binding
EPB55_RS14485	COG0346	lactoylglutathione lyase activity
EPB55_RS14490	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EPB55_RS14495	COG4660	Part of a membrane complex involved in electron transport
EPB55_RS14500	COG4659	FMN binding
EPB55_RS14510	COG4656	Part of a membrane complex involved in electron transport
EPB55_RS14515	COG2878	Part of a membrane complex involved in electron transport
EPB55_RS14520	COG4657	Part of a membrane complex involved in electron transport
EPB55_RS14535	COG0556	nucleotide-excision repair
EPB55_RS14540	COG2204	response regulator
EPB55_RS14545	COG2198	Histidine kinase
EPB55_RS14550	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EPB55_RS14560	COG0521	Mo-molybdopterin cofactor biosynthetic process
EPB55_RS14570	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EPB55_RS14575	COG0314	molybdopterin synthase activity
EPB55_RS14585	COG0601	transmembrane transport
EPB55_RS14590	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EPB55_RS14595	COG0444	Belongs to the ABC transporter superfamily
EPB55_RS14605	COG0435	Glutathione S-transferase
EPB55_RS14615	COG2350	Protein conserved in bacteria
EPB55_RS14635	COG1301	dicarboxylic acid transport
EPB55_RS14645	COG0133	tryptophan synthase activity
EPB55_RS14650	COG0135	phosphoribosylanthranilate isomerase activity
EPB55_RS14650	COG0134	indole-3-glycerol-phosphate synthase activity
EPB55_RS14655	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EPB55_RS14660	COG0512	Glutamine amidotransferase of anthranilate synthase
EPB55_RS14665	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EPB55_RS14675	COG0613	PHP domain protein
EPB55_RS14680	COG0009	L-threonylcarbamoyladenylate synthase
EPB55_RS14700	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EPB55_RS14710	COG5001	Diguanylate cyclase
EPB55_RS14715	COG0417	DNA replication proofreading
EPB55_RS14720	COG2197	response regulator
EPB55_RS14790	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EPB55_RS14795	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EPB55_RS14800	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EPB55_RS14820	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
EPB55_RS14825	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
EPB55_RS14830	COG0437	4 iron, 4 sulfur cluster binding
EPB55_RS14835	COG3301	Polysulphide reductase, NrfD
EPB55_RS14840	COG1138	Cytochrome C-type biogenesis protein
EPB55_RS14845	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EPB55_RS14850	COG4235	cytochrome complex assembly
EPB55_RS14850	COG3088	subunit of a heme lyase
EPB55_RS14860	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EPB55_RS14860	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EPB55_RS14865	COG0489	protein tyrosine kinase activity
EPB55_RS14870	COG0572	uridine kinase
EPB55_RS14880	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
EPB55_RS14885	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EPB55_RS14890	COG0659	secondary active sulfate transmembrane transporter activity
EPB55_RS14895	COG1530	ribonuclease E activity
EPB55_RS14905	COG0424	maF-like protein
EPB55_RS14910	COG1399	metal-binding, possibly nucleic acid-binding protein
EPB55_RS14915	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EPB55_RS14920	COG0416	fatty acid biosynthetic process
EPB55_RS14925	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EPB55_RS14940	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EPB55_RS14955	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EPB55_RS14960	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EPB55_RS14970	COG0084	hydrolase, TatD family'
EPB55_RS14975	COG1263	PTS System
EPB55_RS14975	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EPB55_RS14990	COG0733	neurotransmitter:sodium symporter activity
EPB55_RS15005	COG4667	esterase of the alpha-beta hydrolase superfamily
EPB55_RS15010	COG0469	pyruvate kinase activity
EPB55_RS15015	COG1940	carbohydrate kinase activity
EPB55_RS15020	COG0784	Response regulator, receiver
EPB55_RS15020	COG0835	chemotaxis
EPB55_RS15040	COG1028	Short-chain dehydrogenase reductase Sdr
EPB55_RS15045	COG0616	signal peptide processing
EPB55_RS15055	COG0539	negative regulation of cytoplasmic translation
EPB55_RS15065	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
EPB55_RS15070	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
EPB55_RS15075	COG0284	orotidine-5'-phosphate decarboxylase activity
EPB55_RS15080	COG4174	ABC transporter (Permease)
EPB55_RS15085	COG4239	(ABC) transporter, permease
EPB55_RS15090	COG4166	transmembrane transport
EPB55_RS15095	COG0444	Belongs to the ABC transporter superfamily
EPB55_RS15100	COG4608	Belongs to the ABC transporter superfamily
EPB55_RS15145	COG0583	DNA-binding transcription factor activity
EPB55_RS15155	COG0686	Belongs to the AlaDH PNT family
EPB55_RS15170	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EPB55_RS15175	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EPB55_RS15190	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EPB55_RS15205	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
EPB55_RS15210	COG0501	Belongs to the peptidase M48B family
EPB55_RS15220	COG1028	Short-chain dehydrogenase reductase Sdr
EPB55_RS15255	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EPB55_RS15260	COG2915	High frequency lysogenization protein hflD homolog
EPB55_RS15275	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EPB55_RS15280	COG2916	Histone family protein nucleoid-structuring protein H-NS
EPB55_RS15285	COG1757	Na H antiporter
EPB55_RS15290	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EPB55_RS15295	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EPB55_RS15300	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EPB55_RS15305	COG0131	Imidazoleglycerol-phosphate dehydratase
EPB55_RS15305	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EPB55_RS15310	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EPB55_RS15315	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EPB55_RS15320	COG0107	imidazoleglycerol-phosphate synthase activity
EPB55_RS15330	COG3012	SEC-C Motif Domain Protein
EPB55_RS15335	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
EPB55_RS15340	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EPB55_RS15345	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EPB55_RS15350	COG0215	cysteine-tRNA ligase activity
EPB55_RS15355	COG1435	thymidine kinase activity
EPB55_RS15365	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EPB55_RS15370	COG0583	DNA-binding transcription factor activity
EPB55_RS15390	COG2116	formate transmembrane transporter activity
EPB55_RS15395	COG0390	transport system, permease component
EPB55_RS15400	COG4459	periplasmic nitrate reductase
EPB55_RS15405	COG3005	denitrification pathway
EPB55_RS15410	COG0243	molybdopterin cofactor binding
EPB55_RS15440	COG1227	inorganic diphosphatase activity
EPB55_RS15455	COG4172	Belongs to the ABC transporter superfamily
EPB55_RS15480	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EPB55_RS15485	COG1842	Phage shock protein A
EPB55_RS15495	COG1983	PspC domain protein
EPB55_RS15515	COG2818	Glycosylase
EPB55_RS15520	COG0626	cystathionine gamma-synthase activity
EPB55_RS15530	COG0733	neurotransmitter:sodium symporter activity
EPB55_RS15540	COG0564	pseudouridine synthase activity
EPB55_RS15550	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EPB55_RS15555	COG1151	hydroxylamine reductase activity
EPB55_RS15560	COG3604	Transcriptional regulator
EPB55_RS15565	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EPB55_RS15570	COG4136	ATPase activity
EPB55_RS15575	COG4135	transport system, permease component
EPB55_RS15580	COG4134	Bacterial extracellular solute-binding protein
EPB55_RS15590	COG3313	Fe-S protein
EPB55_RS15615	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EPB55_RS15620	COG2205	protein histidine kinase activity
EPB55_RS15635	COG1061	Type III restriction enzyme res subunit
EPB55_RS15645	COG2814	Major facilitator Superfamily
EPB55_RS15660	COG0702	epimerase
EPB55_RS15665	COG1136	(ABC) transporter
EPB55_RS15680	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EPB55_RS15700	COG3273	potassium ion transport
EPB55_RS15700	COG2985	domain, Protein
EPB55_RS15705	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EPB55_RS15710	COG1979	alcohol dehydrogenase
EPB55_RS15715	COG1737	Transcriptional regulator
EPB55_RS15720	COG0076	glutamate decarboxylase activity
EPB55_RS15730	COG2431	L-lysine efflux transmembrane transporter activity
EPB55_RS15740	COG3070	regulator of competence-specific genes
EPB55_RS15755	COG5002	protein histidine kinase activity
EPB55_RS15755	COG5002	protein histidine kinase activity
EPB55_RS15770	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EPB55_RS15775	COG4988	ABC transporter
EPB55_RS15780	COG0492	ferredoxin-NADP+ reductase activity
EPB55_RS15790	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EPB55_RS15805	COG3385	transposase activity
EPB55_RS15810	COG0471	metal ion transport
EPB55_RS15815	COG2949	membrane
EPB55_RS15820	COG0281	malic enzyme
EPB55_RS15825	COG1643	Atp-dependent helicase
EPB55_RS15840	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EPB55_RS15850	COG1346	cytolysis
EPB55_RS15855	COG1380	Effector of murein hydrolase LrgA
EPB55_RS15875	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
EPB55_RS15895	COG2988	succinylglutamate desuccinylase activity
EPB55_RS15905	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
EPB55_RS15925	COG0583	DNA-binding transcription factor activity
EPB55_RS15935	COG1451	nucleotide metabolic process
EPB55_RS15950	COG3063	Type IV pilus biogenesis stability protein PilW
EPB55_RS15960	COG0737	Belongs to the 5'-nucleotidase family
EPB55_RS15965	COG2195	Cleaves the N-terminal amino acid of tripeptides
EPB55_RS15975	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
EPB55_RS15985	COG0625	glutathione transferase activity
EPB55_RS16035	COG0121	glutamine amidotransferase
EPB55_RS16040	COG0531	amino acid
EPB55_RS16050	COG1522	sequence-specific DNA binding
EPB55_RS16070	COG2963	transposase activity
EPB55_RS16075	COG2801	Transposase and inactivated derivatives
EPB55_RS16080	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EPB55_RS16085	COG0583	DNA-binding transcription factor activity
EPB55_RS16110	COG5002	protein histidine kinase activity
EPB55_RS16110	COG2205	protein histidine kinase activity
EPB55_RS16110	COG0784	Response regulator, receiver
EPB55_RS16115	COG0534	Mate efflux family protein
EPB55_RS16120	COG2926	Belongs to the UPF0265 family
EPB55_RS16130	COG3132	Protein of unknown function, DUF480
EPB55_RS16135	COG2827	Endonuclease containing a URI domain
EPB55_RS16145	COG1879	ABC-type sugar transport system periplasmic component
EPB55_RS16185	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EPB55_RS16190	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EPB55_RS16200	COG0183	Belongs to the thiolase family
EPB55_RS16225	COG3005	denitrification pathway
EPB55_RS16235	COG0243	molybdopterin cofactor binding
EPB55_RS16245	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EPB55_RS16250	COG3850	Histidine kinase
EPB55_RS16255	COG2197	response regulator
EPB55_RS16275	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EPB55_RS16275	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EPB55_RS16285	COG0516	GMP reductase activity
EPB55_RS16300	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EPB55_RS16315	COG3568	Endonuclease Exonuclease Phosphatase
EPB55_RS16340	COG0513	Belongs to the DEAD box helicase family
EPB55_RS16355	COG1846	Transcriptional regulator
EPB55_RS16380	COG0842	Transport permease protein
EPB55_RS16385	COG1131	(ABC) transporter
EPB55_RS16395	COG1737	Transcriptional regulator
EPB55_RS16395	COG0837	glucose binding
EPB55_RS16405	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
EPB55_RS16415	COG4145	pantothenate transmembrane transporter activity
EPB55_RS16430	COG0251	oxidation-reduction process
EPB55_RS16435	COG2203	Gaf domain
EPB55_RS16435	COG3706	GGDEF domain
EPB55_RS16435	COG4251	negative regulation of phosphorylation
EPB55_RS16435	COG5001	Diguanylate cyclase
EPB55_RS16440	COG0583	DNA-binding transcription factor activity
EPB55_RS16445	COG2814	Major facilitator Superfamily
EPB55_RS16460	COG0697	spore germination
EPB55_RS16475	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EPB55_RS16485	COG1764	response to oxidative stress
EPB55_RS16490	COG1846	Transcriptional regulator
EPB55_RS16515	COG1280	lysine exporter protein (LysE YggA)
EPB55_RS16525	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EPB55_RS16530	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EPB55_RS16535	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EPB55_RS16540	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
EPB55_RS16565	COG1612	heme a metabolic process
EPB55_RS16570	COG0109	protoheme IX farnesyltransferase activity
EPB55_RS16575	COG2885	chlorophyll binding
EPB55_RS16580	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EPB55_RS16585	COG0840	transmembrane signaling receptor activity
EPB55_RS16600	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EPB55_RS16605	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EPB55_RS16625	COG2897	thiosulfate sulfurtransferase activity
EPB55_RS16635	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EPB55_RS16640	COG0303	'Molybdopterin
EPB55_RS16645	COG0302	gtp cyclohydrolase
EPB55_RS16650	COG1914	H( )-stimulated, divalent metal cation uptake system
EPB55_RS16660	COG0038	chloride channel
EPB55_RS16680	COG4989	oxidoreductase activity
EPB55_RS16690	COG2195	Cleaves the N-terminal amino acid of tripeptides
EPB55_RS16710	COG0840	transmembrane signaling receptor activity
EPB55_RS16715	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EPB55_RS16720	COG0545	Peptidyl-prolyl cis-trans isomerase
EPB55_RS16725	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EPB55_RS16750	COG1278	Cold shock
EPB55_RS16755	COG3036	rescue of stalled ribosome
EPB55_RS16765	COG2199	diguanylate cyclase activity
EPB55_RS16765	COG2203	Gaf domain
EPB55_RS16775	COG1482	cell wall glycoprotein biosynthetic process
EPB55_RS16780	COG2271	Major facilitator Superfamily
EPB55_RS16785	COG3851	Histidine kinase
EPB55_RS16790	COG2197	response regulator
EPB55_RS16810	COG2130	NADP-dependent
EPB55_RS16815	COG1309	transcriptional regulator
EPB55_RS16830	COG1278	Cold shock
EPB55_RS16855	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EPB55_RS16860	COG1960	acyl-CoA dehydrogenase activity
EPB55_RS16870	COG0183	Belongs to the thiolase family
EPB55_RS16880	COG1960	acyl-CoA dehydrogenase activity
EPB55_RS16885	COG1024	Enoyl-CoA hydratase
EPB55_RS16890	COG1024	Enoyl-CoA hydratase
EPB55_RS16900	COG1028	Short-chain dehydrogenase reductase Sdr
EPB55_RS16925	COG2994	toxin metabolic process
EPB55_RS16930	COG1073	alpha beta
EPB55_RS16930	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
EPB55_RS16930	COG3064	Membrane
EPB55_RS16985	COG3437	response regulator, receiver
EPB55_RS16985	COG0784	Response regulator, receiver
EPB55_RS16990	COG4191	Histidine kinase
EPB55_RS16990	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EPB55_RS17000	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
EPB55_RS17025	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EPB55_RS17030	COG3186	Phenylalanine-4-hydroxylase
EPB55_RS17035	COG2154	pterin-4-alpha-carbinolamine dehydratase
EPB55_RS17055	COG3530	Putative quorum-sensing-regulated virulence factor
EPB55_RS17075	COG0515	serine threonine protein kinase
EPB55_RS17075	COG2815	serine threonine protein kinase
EPB55_RS17110	COG0631	protein serine/threonine phosphatase activity
EPB55_RS17270	COG0501	Belongs to the peptidase M48B family
EPB55_RS17275	COG1704	LemA family
EPB55_RS17280	COG3069	C4-dicarboxylate transmembrane transporter activity
EPB55_RS17290	COG0312	modulator of DNA gyrase
EPB55_RS17295	COG0312	modulator of DNA gyrase
EPB55_RS17300	COG0584	glycerophosphoryl diester phosphodiesterase
EPB55_RS17305	COG2271	Major facilitator Superfamily
EPB55_RS17320	COG0840	transmembrane signaling receptor activity
EPB55_RS17325	COG0840	transmembrane signaling receptor activity
EPB55_RS17330	COG0366	Alpha amylase catalytic
EPB55_RS17335	COG1214	PFAM Peptidase M22, glycoprotease
EPB55_RS17335	COG0456	acetyltransferase
EPB55_RS17340	COG0243	molybdopterin cofactor binding
EPB55_RS17345	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EPB55_RS17345	COG1648	precorrin-2 dehydrogenase activity
EPB55_RS17360	COG3707	response regulator
EPB55_RS17365	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EPB55_RS17365	COG1116	anion transmembrane transporter activity
EPB55_RS17370	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EPB55_RS17375	COG1116	anion transmembrane transporter activity
EPB55_RS17405	COG0523	cobalamin synthesis protein
EPB55_RS17415	COG0513	Belongs to the DEAD box helicase family
EPB55_RS17420	COG0010	Belongs to the arginase family
EPB55_RS17430	COG2203	Gaf domain
EPB55_RS17430	COG4251	negative regulation of phosphorylation
EPB55_RS17430	COG5001	Diguanylate cyclase
EPB55_RS17430	COG3706	GGDEF domain
EPB55_RS17440	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EPB55_RS17475	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EPB55_RS17510	COG0811	peptide transport
EPB55_RS17515	COG0811	peptide transport
EPB55_RS17520	COG0848	biopolymer transport protein
EPB55_RS17535	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EPB55_RS17555	COG0534	Mate efflux family protein
EPB55_RS17565	COG0477	Major facilitator Superfamily
EPB55_RS17570	COG3118	belongs to the thioredoxin family
EPB55_RS17575	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EPB55_RS17630	COG1328	CTP reductase activity
EPB55_RS17635	COG0602	queuosine metabolic process
EPB55_RS17640	COG0840	transmembrane signaling receptor activity
EPB55_RS17650	COG0189	ligase activity
EPB55_RS17650	COG4067	protein conserved in archaea
EPB55_RS17670	COG0725	ABC transporter, periplasmic molybdate-binding protein
EPB55_RS17675	COG4149	molybdate abc transporter
EPB55_RS17685	COG0697	spore germination
EPB55_RS17690	COG1846	Transcriptional regulator
EPB55_RS17700	COG2199	diguanylate cyclase activity
EPB55_RS17725	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
EPB55_RS17730	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
EPB55_RS17740	COG0745	RESPONSE REGULATOR receiver
EPB55_RS17755	COG3140	Belongs to the UPF0181 family
EPB55_RS17845	COG0023	Translation Initiation Factor
EPB55_RS17865	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EPB55_RS17865	COG1042	CoA-binding domain protein
EPB55_RS17865	COG0045	succinate-CoA ligase (ADP-forming) activity
EPB55_RS17870	COG0583	DNA-binding transcription factor activity
EPB55_RS17875	COG4771	TonB-dependent receptor
EPB55_RS17875	COG1629	transport
EPB55_RS17880	COG3447	MASE1 domain protein
EPB55_RS17880	COG5002	protein histidine kinase activity
EPB55_RS17880	COG5001	Diguanylate cyclase
EPB55_RS17890	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
EPB55_RS17895	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EPB55_RS17900	COG1984	allophanate hydrolase subunit 2
EPB55_RS17905	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
EPB55_RS17905	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EPB55_RS17910	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
EPB55_RS17915	COG4181	ATPase activity
EPB55_RS17925	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EPB55_RS17930	COG5001	Diguanylate cyclase
EPB55_RS17930	COG1716	ATPase activity
EPB55_RS17945	COG0484	heat shock protein binding
EPB55_RS17965	COG0583	DNA-binding transcription factor activity
EPB55_RS17970	COG0366	Alpha amylase catalytic
EPB55_RS17980	COG4533	DNA binding
EPB55_RS17990	COG2050	protein possibly involved in aromatic compounds catabolism
EPB55_RS18005	COG2067	long-chain fatty acid transport protein
EPB55_RS18010	COG2267	carboxylic ester hydrolase activity
EPB55_RS18040	COG0861	Integral membrane protein TerC family
EPB55_RS18045	COG0737	Belongs to the 5'-nucleotidase family
EPB55_RS18050	COG3593	DNA synthesis involved in DNA repair
EPB55_RS18060	COG0583	DNA-binding transcription factor activity
EPB55_RS18065	COG2116	formate transmembrane transporter activity
EPB55_RS18070	COG3385	transposase activity
EPB55_RS18075	COG2353	YceI-like domain
EPB55_RS18080	COG3038	cytochrome b561
EPB55_RS18095	COG0513	Belongs to the DEAD box helicase family
EPB55_RS18110	COG0546	phosphoglycolate phosphatase activity
EPB55_RS18115	COG0784	Response regulator, receiver
EPB55_RS18115	COG3437	response regulator, receiver
EPB55_RS18130	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EPB55_RS18135	COG2759	Belongs to the formate--tetrahydrofolate ligase family
EPB55_RS18140	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EPB55_RS18150	COG2207	Transcriptional regulator
EPB55_RS18155	COG1979	alcohol dehydrogenase
EPB55_RS18165	COG4191	Histidine kinase
EPB55_RS18175	COG2271	Major facilitator Superfamily
EPB55_RS18180	COG0469	pyruvate kinase activity
EPB55_RS18205	COG1609	Transcriptional regulator
EPB55_RS18210	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EPB55_RS18210	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EPB55_RS18215	COG1105	Belongs to the carbohydrate kinase PfkB family
EPB55_RS18220	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EPB55_RS18220	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EPB55_RS18220	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
EPB55_RS18265	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EPB55_RS18270	COG0509	glycine decarboxylation via glycine cleavage system
EPB55_RS18285	COG1132	(ABC) transporter
EPB55_RS18295	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EPB55_RS18295	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EPB55_RS18325	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EPB55_RS18330	COG0583	DNA-binding transcription factor activity
EPB55_RS18350	COG2814	Major facilitator Superfamily
EPB55_RS18355	COG3385	transposase activity
EPB55_RS18385	COG0641	radical SAM
EPB55_RS18395	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
EPB55_RS18430	COG0714	Associated with various cellular activities
EPB55_RS18435	COG0641	radical SAM
EPB55_RS18440	COG3119	arylsulfatase activity
EPB55_RS18450	COG3119	arylsulfatase activity
EPB55_RS18455	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EPB55_RS18460	COG0513	Belongs to the DEAD box helicase family
EPB55_RS18465	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
EPB55_RS18480	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EPB55_RS18505	COG5001	Diguanylate cyclase
EPB55_RS18505	COG1716	ATPase activity
EPB55_RS18515	COG0513	Belongs to the DEAD box helicase family
EPB55_RS18540	COG3005	denitrification pathway
EPB55_RS18545	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EPB55_RS18570	COG1879	ABC-type sugar transport system periplasmic component
EPB55_RS18575	COG1803	Methylglyoxal synthase
EPB55_RS18580	COG0210	DNA helicase
EPB55_RS18585	COG1289	transmembrane transporter activity
EPB55_RS18615	COG0789	Transcriptional regulator
EPB55_RS18620	COG4604	ABC transporter, ATP-binding protein
EPB55_RS18625	COG4605	iron ion homeostasis
EPB55_RS18630	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EPB55_RS18650	COG0110	maltose O-acetyltransferase activity
EPB55_RS18660	COG3290	protein histidine kinase activity
EPB55_RS18665	COG0471	metal ion transport
EPB55_RS18750	COG4964	Belongs to the GSP D family
EPB55_RS18770	COG0583	DNA-binding transcription factor activity
EPB55_RS18780	COG0419	ATPase involved in DNA repair
EPB55_RS18785	COG0420	3'-5' exonuclease activity
EPB55_RS18790	COG3437	response regulator, receiver
EPB55_RS18805	COG2172	sigma factor antagonist activity
EPB55_RS18815	COG1366	Belongs to the anti-sigma-factor antagonist family
EPB55_RS18830	COG0456	acetyltransferase
EPB55_RS18840	COG0835	chemotaxis
EPB55_RS18840	COG0784	Response regulator, receiver
EPB55_RS18850	COG1609	Transcriptional regulator
EPB55_RS18855	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EPB55_RS18860	COG1879	ABC-type sugar transport system periplasmic component
EPB55_RS18865	COG1172	Belongs to the binding-protein-dependent transport system permease family
EPB55_RS18875	COG1869	D-ribose catabolic process
EPB55_RS18890	COG2315	Protein conserved in bacteria
EPB55_RS18895	COG2425	protein containing a von Willebrand factor type A (vWA) domain
EPB55_RS18910	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
EPB55_RS18925	COG1288	antiporter activity
EPB55_RS18935	COG0671	phosphoesterase, PA-phosphatase related
EPB55_RS18940	COG3097	Belongs to the UPF0267 family
EPB55_RS18950	COG2962	Rard protein
EPB55_RS18975	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EPB55_RS18980	COG0814	amino acid
EPB55_RS19005	COG3174	membrane
EPB55_RS19010	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EPB55_RS19040	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EPB55_RS19045	COG0443	Heat shock 70 kDa protein
EPB55_RS19050	COG1454	alcohol dehydrogenase
EPB55_RS19060	COG2133	pyrroloquinoline quinone binding
EPB55_RS19065	COG1619	proteins homologs of microcin C7 resistance protein MccF
EPB55_RS19075	COG0546	phosphoglycolate phosphatase activity
EPB55_RS19080	COG0247	lactate metabolic process
EPB55_RS19090	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EPB55_RS19110	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EPB55_RS19120	COG3059	membrane
EPB55_RS19125	COG4175	Glycine betaine
EPB55_RS19145	COG1012	belongs to the aldehyde dehydrogenase family
EPB55_RS19150	COG1309	transcriptional regulator
EPB55_RS19170	COG1686	Belongs to the peptidase S11 family
EPB55_RS19190	COG1760	l-serine dehydratase
EPB55_RS19195	COG3104	oligopeptide transport
EPB55_RS19205	COG0583	DNA-binding transcription factor activity
EPB55_RS19210	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EPB55_RS19230	COG3842	ATPase activity
EPB55_RS19235	COG1840	ABC-type Fe3 transport system, periplasmic component
EPB55_RS19240	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EPB55_RS19245	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EPB55_RS19250	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EPB55_RS19255	COG2207	Transcriptional regulator
EPB55_RS19255	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EPB55_RS19260	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EPB55_RS19285	COG1011	Hydrolase
EPB55_RS19310	COG1765	OsmC-like protein
EPB55_RS19315	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EPB55_RS19315	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EPB55_RS19320	COG3706	GGDEF domain
EPB55_RS19335	COG0840	transmembrane signaling receptor activity
EPB55_RS19355	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EPB55_RS19380	COG2084	Dehydrogenase
EPB55_RS19395	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EPB55_RS19400	COG0739	heme binding
EPB55_RS19435	COG0840	transmembrane signaling receptor activity
EPB55_RS19445	COG0366	Alpha amylase catalytic
EPB55_RS19450	COG0589	response to stress
EPB55_RS19455	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EPB55_RS19460	COG0784	Response regulator, receiver
EPB55_RS19460	COG0835	chemotaxis
EPB55_RS19470	COG0748	coenzyme F420 binding
EPB55_RS19475	COG3721	Heme iron utilization protein
EPB55_RS19485	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
EPB55_RS19490	COG0811	peptide transport
EPB55_RS19495	COG0848	biopolymer transport protein
EPB55_RS19505	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EPB55_RS19510	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
EPB55_RS19555	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EPB55_RS19560	COG3217	Mosc domain protein beta barrel domain protein
EPB55_RS19560	COG3217	Mosc domain protein beta barrel domain protein
EPB55_RS19560	COG0633	Ferredoxin
EPB55_RS19560	COG0633	Ferredoxin
EPB55_RS19565	COG0418	dihydroorotase activity
EPB55_RS19575	COG2354	Protein conserved in bacteria
EPB55_RS19605	COG3833	ABC-type maltose transport systems, permease component
EPB55_RS19610	COG1175	transmembrane transport
EPB55_RS19620	COG3842	ATPase activity
EPB55_RS19625	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EPB55_RS19635	COG1596	polysaccharide export
EPB55_RS19705	COG0714	Associated with various cellular activities
EPB55_RS19725	COG2304	oxidoreductase activity
EPB55_RS19735	COG3706	GGDEF domain
EPB55_RS19735	COG2203	Gaf domain
EPB55_RS19735	COG4251	negative regulation of phosphorylation
EPB55_RS19735	COG5001	Diguanylate cyclase
EPB55_RS19740	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EPB55_RS19745	COG0581	inorganic phosphate transmembrane transporter activity
EPB55_RS19750	COG0573	inorganic phosphate transmembrane transporter activity
EPB55_RS19795	COG0513	Belongs to the DEAD box helicase family
EPB55_RS19805	COG1376	ErfK ybiS ycfS ynhG family protein
EPB55_RS19805	COG1388	LysM domain
EPB55_RS19810	COG0415	Belongs to the DNA photolyase family
EPB55_RS19815	COG0789	Transcriptional regulator
EPB55_RS19820	COG3272	Protein of unknown function (DUF1722)
EPB55_RS19825	COG0813	purine-nucleoside phosphorylase activity
EPB55_RS19850	COG1566	PFAM secretion protein HlyD family protein
EPB55_RS19855	COG4720	Psort location CytoplasmicMembrane, score
EPB55_RS19860	COG1122	ATPase activity
EPB55_RS19875	COG4946	Tricorn protease homolog
EPB55_RS19875	COG0793	Belongs to the peptidase S41A family
EPB55_RS19880	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EPB55_RS19905	COG0668	transmembrane transport
EPB55_RS19925	COG1538	Outer membrane efflux protein
EPB55_RS19935	COG2274	protein secretion by the type I secretion system
EPB55_RS19945	COG3111	PFAM Bacterial OB fold (BOF) protein
EPB55_RS19950	COG2205	protein histidine kinase activity
EPB55_RS19950	COG0784	Response regulator, receiver
EPB55_RS19970	COG2197	response regulator
EPB55_RS19980	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
EPB55_RS20005	COG3040	lipid binding
EPB55_RS20065	COG3240	lipase activity
EPB55_RS20080	COG2211	Major facilitator Superfamily
EPB55_RS20090	COG0346	lactoylglutathione lyase activity
EPB55_RS20105	COG0753	catalase activity
EPB55_RS20125	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EPB55_RS20135	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
EPB55_RS20150	COG0393	Putative heavy-metal-binding
EPB55_RS20170	COG4771	TonB-dependent receptor
EPB55_RS20175	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EPB55_RS20180	COG0039	L-malate dehydrogenase activity
EPB55_RS20195	COG2814	Major facilitator Superfamily
EPB55_RS20270	COG0351	phosphomethylpyrimidine kinase
EPB55_RS20275	COG0671	phosphoesterase, PA-phosphatase related
EPB55_RS20290	COG0561	phosphatase activity
EPB55_RS20300	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EPB55_RS20310	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EPB55_RS20335	COG4221	oxidoreductase activity
EPB55_RS20350	COG0745	RESPONSE REGULATOR receiver
EPB55_RS20355	COG2205	protein histidine kinase activity
EPB55_RS20360	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EPB55_RS20365	COG2194	sulfuric ester hydrolase activity
EPB55_RS20370	COG1368	sulfuric ester hydrolase activity
EPB55_RS20385	COG2356	endonuclease I
EPB55_RS20400	COG3706	GGDEF domain
EPB55_RS20410	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EPB55_RS20445	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EPB55_RS20490	COG1301	dicarboxylic acid transport
EPB55_RS20500	COG0137	argininosuccinate synthase activity
EPB55_RS20515	COG0583	DNA-binding transcription factor activity
EPB55_RS20570	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EPB55_RS20575	COG1482	cell wall glycoprotein biosynthetic process
EPB55_RS20580	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EPB55_RS20585	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EPB55_RS20585	COG1263	PTS System
EPB55_RS20590	COG1609	Transcriptional regulator
EPB55_RS20600	COG3383	formate dehydrogenase (NAD+) activity
EPB55_RS20620	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EPB55_RS20645	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EPB55_RS20655	COG2207	Transcriptional regulator
EPB55_RS20660	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EPB55_RS20660	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EPB55_RS20660	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EPB55_RS20665	COG1482	cell wall glycoprotein biosynthetic process
EPB55_RS20730	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
EPB55_RS20735	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
EPB55_RS20740	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EPB55_RS20745	COG2211	Major facilitator Superfamily
EPB55_RS20765	COG1129	ABC transporter
EPB55_RS20775	COG1609	Transcriptional regulator
EPB55_RS20800	COG0564	pseudouridine synthase activity
EPB55_RS20835	COG1566	PFAM secretion protein HlyD family protein
EPB55_RS20845	COG0534	Mate efflux family protein
EPB55_RS20850	COG1472	Belongs to the glycosyl hydrolase 3 family
EPB55_RS20860	COG4580	involved in the transport of maltose and maltodextrins
EPB55_RS20875	COG1609	Transcriptional regulator
EPB55_RS20885	COG4608	Belongs to the ABC transporter superfamily
EPB55_RS20890	COG0444	Belongs to the ABC transporter superfamily
EPB55_RS20895	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EPB55_RS20905	COG0747	negative chemotaxis
EPB55_RS20915	COG1609	Transcriptional regulator
EPB55_RS20920	COG3842	ATPase activity
EPB55_RS20930	COG0395	ABC-type sugar transport system, permease component
EPB55_RS20945	COG1609	Transcriptional regulator
EPB55_RS20960	COG2199	diguanylate cyclase activity
EPB55_RS20975	COG1028	Short-chain dehydrogenase reductase Sdr
EPB55_RS20990	COG0642	Histidine kinase
EPB55_RS21000	COG0586	Pfam SNARE associated Golgi protein
EPB55_RS21005	COG0387	Pfam Sodium calcium exchanger
EPB55_RS21015	COG0583	DNA-binding transcription factor activity
EPB55_RS21020	COG0583	DNA-binding transcription factor activity
EPB55_RS21030	COG0612	Peptidase, M16
EPB55_RS21035	COG1283	sodium-dependent phosphate transmembrane transporter activity
EPB55_RS21040	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
EPB55_RS21045	COG0625	glutathione transferase activity
EPB55_RS21050	COG1012	belongs to the aldehyde dehydrogenase family
EPB55_RS21110	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EPB55_RS21115	COG0840	transmembrane signaling receptor activity
EPB55_RS21125	COG1640	4-alpha-glucanotransferase
EPB55_RS21130	COG0058	SHG alpha-glucan phosphorylase activity
EPB55_RS21135	COG2909	trisaccharide binding
EPB55_RS21150	COG1999	signal sequence binding
EPB55_RS21155	COG2847	Copper chaperone PCu(A)C
EPB55_RS21160	COG1162	GTPase activity
EPB55_RS21165	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
EPB55_RS21170	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
EPB55_RS21175	COG0531	amino acid
EPB55_RS21180	COG1982	Orn Lys Arg decarboxylase major
EPB55_RS21235	COG3706	GGDEF domain
EPB55_RS21240	COG5001	Diguanylate cyclase
EPB55_RS21250	COG1741	Belongs to the pirin family
EPB55_RS21255	COG3123	guanosine phosphorylase activity
EPB55_RS21275	COG1309	transcriptional regulator
EPB55_RS21300	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EPB55_RS21305	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EPB55_RS21310	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EPB55_RS21330	COG0189	ligase activity
EPB55_RS21345	COG0363	glucosamine-6-phosphate deaminase activity
EPB55_RS21355	COG0786	glutamate:sodium symporter activity
EPB55_RS21360	COG0786	glutamate:sodium symporter activity
EPB55_RS21380	COG3275	phosphorelay sensor kinase activity
EPB55_RS21395	COG4591	ABC-type transport system involved in lipoprotein release permease component
EPB55_RS21400	COG1136	(ABC) transporter
EPB55_RS21410	COG0583	DNA-binding transcription factor activity
EPB55_RS21420	COG0217	transcriptional regulatory protein
EPB55_RS21450	COG0444	Belongs to the ABC transporter superfamily
EPB55_RS21455	COG4608	Belongs to the ABC transporter superfamily
EPB55_RS21480	COG1444	tRNA N-acetyltransferase activity
EPB55_RS21490	COG0745	RESPONSE REGULATOR receiver
EPB55_RS21505	COG0835	chemotaxis
EPB55_RS21510	COG0840	transmembrane signaling receptor activity
EPB55_RS21515	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EPB55_RS21525	COG2201	protein-glutamate methylesterase activity
EPB55_RS21530	COG0840	transmembrane signaling receptor activity
EPB55_RS21575	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EPB55_RS21590	COG0406	alpha-ribazole phosphatase activity
EPB55_RS21595	COG2203	Gaf domain
EPB55_RS21595	COG2200	EAL domain
EPB55_RS21595	COG2199	diguanylate cyclase activity
EPB55_RS21605	COG1263	PTS System
EPB55_RS21605	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EPB55_RS21610	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EPB55_RS21620	COG1737	Transcriptional regulator
EPB55_RS21625	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EPB55_RS21625	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EPB55_RS21640	COG0110	maltose O-acetyltransferase activity
EPB55_RS21645	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EPB55_RS21650	COG0459	protein refolding
EPB55_RS21665	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EPB55_RS21670	COG3069	C4-dicarboxylate transmembrane transporter activity
EPB55_RS21700	COG2204	response regulator
EPB55_RS21710	COG0259	pyridoxamine-phosphate oxidase activity
EPB55_RS21735	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EPB55_RS21755	COG5492	domain, Protein
EPB55_RS21760	COG3119	arylsulfatase activity
EPB55_RS21765	COG3119	arylsulfatase activity
EPB55_RS21770	COG0641	radical SAM
EPB55_RS21775	COG3119	arylsulfatase activity
EPB55_RS21785	COG0747	negative chemotaxis
EPB55_RS21790	COG0601	transmembrane transport
EPB55_RS21795	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EPB55_RS21820	COG0659	secondary active sulfate transmembrane transporter activity
EPB55_RS21825	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EPB55_RS21835	COG1028	Short-chain dehydrogenase reductase Sdr
EPB55_RS21845	COG5426	von Willebrand factor, type A
EPB55_RS21850	COG5492	domain, Protein
EPB55_RS21855	COG1132	(ABC) transporter
EPB55_RS21870	COG3623	hexulose-6-phosphate isomerase
EPB55_RS21875	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
EPB55_RS21880	COG0561	phosphatase activity
EPB55_RS21910	COG1902	pentaerythritol trinitrate reductase activity
EPB55_RS21930	COG0800	Aldolase
EPB55_RS21935	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EPB55_RS21940	COG1904	glucuronate isomerase
EPB55_RS21945	COG0246	Mannitol dehydrogenase
EPB55_RS21955	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
EPB55_RS21965	COG2186	Transcriptional regulator
EPB55_RS21975	COG0513	Belongs to the DEAD box helicase family
EPB55_RS21990	COG1335	isochorismatase
EPB55_RS21995	COG2207	Transcriptional regulator
EPB55_RS21995	COG1917	Cupin 2, conserved barrel domain protein
EPB55_RS22000	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EPB55_RS22005	COG0129	dihydroxy-acid dehydratase activity
EPB55_RS22010	COG4948	Mandelate Racemase Muconate Lactonizing
EPB55_RS22015	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
EPB55_RS22015	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
EPB55_RS22025	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EPB55_RS22030	COG0800	Aldolase
EPB55_RS22035	COG3734	2-keto-3-deoxy-galactonokinase
EPB55_RS22040	COG2186	Transcriptional regulator
EPB55_RS22045	COG2258	MOSC domain
EPB55_RS22065	COG1486	melibiose metabolic process
EPB55_RS22070	COG0583	DNA-binding transcription factor activity
EPB55_RS22090	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EPB55_RS22105	COG0840	transmembrane signaling receptor activity
EPB55_RS22125	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EPB55_RS22130	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EPB55_RS22155	COG2015	COG2015, Alkyl sulfatase and related hydrolases
EPB55_RS22170	COG2207	Transcriptional regulator
EPB55_RS22175	COG0697	spore germination
EPB55_RS22180	COG1349	DNA-binding transcription factor activity
EPB55_RS22185	COG1349	DNA-binding transcription factor activity
EPB55_RS22195	COG2222	sugar isomerase
EPB55_RS22200	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EPB55_RS22210	COG3716	PTS system mannose fructose sorbose family IID component
EPB55_RS22215	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
EPB55_RS22230	COG0488	(ABC) transporter
EPB55_RS22250	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EPB55_RS22255	COG1120	ATPase activity
EPB55_RS22285	COG1136	(ABC) transporter
EPB55_RS22285	COG0577	efflux transmembrane transporter activity
EPB55_RS22290	COG0577	efflux transmembrane transporter activity
EPB55_RS22290	COG1136	(ABC) transporter
EPB55_RS22295	COG2176	DNA-directed DNA polymerase activity
EPB55_RS22345	COG3706	GGDEF domain
EPB55_RS22380	COG2205	protein histidine kinase activity
EPB55_RS22395	COG2015	COG2015, Alkyl sulfatase and related hydrolases
EPB55_RS22425	COG0579	oxidoreductase
EPB55_RS22435	COG3437	response regulator, receiver
EPB55_RS22455	COG1357	PFAM Pentapeptide repeats (8 copies)
EPB55_RS22465	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EPB55_RS22500	COG0513	Belongs to the DEAD box helicase family
EPB55_RS22520	COG0583	DNA-binding transcription factor activity
EPB55_RS22530	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EPB55_RS22560	COG2814	Major facilitator Superfamily
EPB55_RS22580	COG1858	cytochrome C peroxidase
EPB55_RS22615	COG0454	-acetyltransferase
EPB55_RS22640	COG3046	protein related to deoxyribodipyrimidine photolyase
EPB55_RS22645	COG2207	Transcriptional regulator
EPB55_RS22650	COG1881	PFAM PEBP family protein
EPB55_RS22655	COG0494	nUDIX hydrolase
EPB55_RS22685	COG0668	transmembrane transport
EPB55_RS22705	COG3153	acetyltransferase
EPB55_RS22705	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EPB55_RS22745	COG1028	Short-chain dehydrogenase reductase Sdr
EPB55_RS22755	COG1917	Cupin 2, conserved barrel domain protein
EPB55_RS22770	COG0697	spore germination
EPB55_RS22775	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EPB55_RS22780	COG0800	Aldolase
EPB55_RS22810	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EPB55_RS22815	COG0823	Involved in the tonB-independent uptake of proteins
EPB55_RS22820	COG0366	Alpha amylase catalytic
EPB55_RS22830	COG3366	ferrous iron transmembrane transporter activity
EPB55_RS22835	COG0700	Nucleoside recognition
EPB55_RS22840	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EPB55_RS22855	COG0583	DNA-binding transcription factor activity
EPB55_RS22875	COG0640	Transcriptional regulator
EPB55_RS22880	COG0798	PFAM Bile acid sodium symporter
EPB55_RS22900	COG2194	sulfuric ester hydrolase activity
EPB55_RS22920	COG1566	PFAM secretion protein HlyD family protein
EPB55_RS22930	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EPB55_RS22935	COG2203	Gaf domain
EPB55_RS22935	COG5001	Diguanylate cyclase
EPB55_RS22935	COG3706	GGDEF domain
EPB55_RS22935	COG4251	negative regulation of phosphorylation
EPB55_RS22950	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
EPB55_RS22955	COG0583	DNA-binding transcription factor activity
EPB55_RS22965	COG0583	DNA-binding transcription factor activity
EPB55_RS22975	COG2015	COG2015, Alkyl sulfatase and related hydrolases
EPB55_RS23000	COG0673	inositol 2-dehydrogenase activity
EPB55_RS23005	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EPB55_RS23010	COG2197	response regulator
EPB55_RS23025	COG0625	glutathione transferase activity
EPB55_RS23030	COG1879	ABC-type sugar transport system periplasmic component
EPB55_RS23040	COG3284	Transcriptional regulator
EPB55_RS23045	COG1012	belongs to the aldehyde dehydrogenase family
EPB55_RS23055	COG1253	flavin adenine dinucleotide binding
EPB55_RS23080	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EPB55_RS23085	COG1609	Transcriptional regulator
EPB55_RS23100	COG0488	(ABC) transporter
EPB55_RS23105	COG0814	amino acid
EPB55_RS23110	COG3033	Beta-eliminating lyase
EPB55_RS23125	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EPB55_RS23155	COG0189	ligase activity
EPB55_RS23165	COG4774	siderophore transport
EPB55_RS23165	COG1629	transport
EPB55_RS23170	COG4607	ABC-type enterochelin transport system periplasmic component
EPB55_RS23180	COG1021	2,3-dihydroxybenzoate-AMP ligase
EPB55_RS23200	COG1021	2,3-dihydroxybenzoate-AMP ligase
EPB55_RS23205	COG1169	isochorismate synthase
EPB55_RS23210	COG1028	Short-chain dehydrogenase reductase Sdr
EPB55_RS23215	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EPB55_RS23245	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EPB55_RS23250	COG0840	transmembrane signaling receptor activity
EPB55_RS23260	COG2755	lipolytic protein G-D-S-L family
EPB55_RS23265	COG5001	Diguanylate cyclase
EPB55_RS23265	COG5002	protein histidine kinase activity
EPB55_RS23280	COG4160	amino acid transport
EPB55_RS23285	COG4215	(ABC) transporter
EPB55_RS23290	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EPB55_RS23295	COG1126	abc transporter atp-binding protein
EPB55_RS23300	COG3015	lipoprotein NlpE involved in copper resistance
EPB55_RS23315	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EPB55_RS23355	COG2814	Major facilitator Superfamily
EPB55_RS23380	COG1139	Iron-sulfur cluster binding protein
EPB55_RS23390	COG1620	l-lactate permease
EPB55_RS23395	COG0583	DNA-binding transcription factor activity
EPB55_RS23400	COG1505	serine-type exopeptidase activity
EPB55_RS23405	COG4172	Belongs to the ABC transporter superfamily
EPB55_RS23415	COG1067	ATP-dependent peptidase activity
EPB55_RS23420	COG0402	S-adenosylhomocysteine deaminase activity
EPB55_RS23425	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
EPB55_RS23435	COG2239	Acts as a magnesium transporter
EPB55_RS23460	COG0745	RESPONSE REGULATOR receiver