locus-tag	class	description
AL549_RS00035	COG3217	Mosc domain protein beta barrel domain protein
AL549_RS00035	COG0633	Ferredoxin
AL549_RS00035	COG3217	Mosc domain protein beta barrel domain protein
AL549_RS00035	COG0633	Ferredoxin
AL549_RS00040	COG0418	dihydroorotase activity
AL549_RS00050	COG2354	Protein conserved in bacteria
AL549_RS00080	COG3833	ABC-type maltose transport systems, permease component
AL549_RS00085	COG1175	transmembrane transport
AL549_RS00095	COG3842	ATPase activity
AL549_RS00100	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AL549_RS00110	COG1596	polysaccharide export
AL549_RS00115	COG3206	protein involved in exopolysaccharide biosynthesis
AL549_RS00115	COG0489	protein tyrosine kinase activity
AL549_RS00180	COG0714	Associated with various cellular activities
AL549_RS00200	COG2304	oxidoreductase activity
AL549_RS00210	COG3706	GGDEF domain
AL549_RS00210	COG4251	negative regulation of phosphorylation
AL549_RS00210	COG5001	Diguanylate cyclase
AL549_RS00210	COG2203	Gaf domain
AL549_RS00215	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AL549_RS00220	COG0581	inorganic phosphate transmembrane transporter activity
AL549_RS00225	COG0573	inorganic phosphate transmembrane transporter activity
AL549_RS00265	COG0513	Belongs to the DEAD box helicase family
AL549_RS00275	COG1376	ErfK ybiS ycfS ynhG family protein
AL549_RS00275	COG1388	LysM domain
AL549_RS00280	COG0415	Belongs to the DNA photolyase family
AL549_RS00285	COG0789	Transcriptional regulator
AL549_RS00290	COG3272	Protein of unknown function (DUF1722)
AL549_RS00295	COG0813	purine-nucleoside phosphorylase activity
AL549_RS00320	COG1566	PFAM secretion protein HlyD family protein
AL549_RS00325	COG4720	Psort location CytoplasmicMembrane, score
AL549_RS00345	COG0793	Belongs to the peptidase S41A family
AL549_RS00345	COG4946	Tricorn protease homolog
AL549_RS00350	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AL549_RS00375	COG0668	transmembrane transport
AL549_RS00405	COG2274	protein secretion by the type I secretion system
AL549_RS00415	COG3111	PFAM Bacterial OB fold (BOF) protein
AL549_RS00420	COG0784	Response regulator, receiver
AL549_RS00420	COG2205	protein histidine kinase activity
AL549_RS00440	COG2197	response regulator
AL549_RS00450	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
AL549_RS00480	COG3040	lipid binding
AL549_RS00540	COG3240	lipase activity
AL549_RS00555	COG2211	Major facilitator Superfamily
AL549_RS00565	COG0346	lactoylglutathione lyase activity
AL549_RS00580	COG0753	catalase activity
AL549_RS00600	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AL549_RS00610	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AL549_RS00625	COG0393	Putative heavy-metal-binding
AL549_RS00645	COG4771	TonB-dependent receptor
AL549_RS00650	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AL549_RS00655	COG0039	L-malate dehydrogenase activity
AL549_RS00740	COG0351	phosphomethylpyrimidine kinase
AL549_RS00745	COG0671	phosphoesterase, PA-phosphatase related
AL549_RS00760	COG0561	phosphatase activity
AL549_RS00770	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AL549_RS00775	COG0076	glutamate decarboxylase activity
AL549_RS00780	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AL549_RS00805	COG4221	oxidoreductase activity
AL549_RS00820	COG0745	RESPONSE REGULATOR receiver
AL549_RS00825	COG2205	protein histidine kinase activity
AL549_RS00830	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AL549_RS00835	COG2194	sulfuric ester hydrolase activity
AL549_RS00840	COG1368	sulfuric ester hydrolase activity
AL549_RS00870	COG3706	GGDEF domain
AL549_RS00880	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL549_RS00915	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AL549_RS00960	COG1301	dicarboxylic acid transport
AL549_RS00970	COG0137	argininosuccinate synthase activity
AL549_RS00990	COG1733	regulation of RNA biosynthetic process
AL549_RS00995	COG0583	DNA-binding transcription factor activity
AL549_RS01055	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AL549_RS01060	COG0583	DNA-binding transcription factor activity
AL549_RS01070	COG3383	formate dehydrogenase (NAD+) activity
AL549_RS01090	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL549_RS01100	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL549_RS01110	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL549_RS01115	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL549_RS01125	COG2207	Transcriptional regulator
AL549_RS01130	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL549_RS01130	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL549_RS01130	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL549_RS01135	COG1482	cell wall glycoprotein biosynthetic process
AL549_RS01195	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
AL549_RS01200	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AL549_RS01205	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AL549_RS01215	COG2211	Major facilitator Superfamily
AL549_RS01235	COG1129	ABC transporter
AL549_RS01245	COG1609	Transcriptional regulator
AL549_RS01270	COG0564	pseudouridine synthase activity
AL549_RS01305	COG1566	PFAM secretion protein HlyD family protein
AL549_RS01315	COG0534	Mate efflux family protein
AL549_RS01320	COG1472	Belongs to the glycosyl hydrolase 3 family
AL549_RS01330	COG4580	involved in the transport of maltose and maltodextrins
AL549_RS01345	COG1609	Transcriptional regulator
AL549_RS01355	COG4608	Belongs to the ABC transporter superfamily
AL549_RS01360	COG0444	Belongs to the ABC transporter superfamily
AL549_RS01365	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL549_RS01375	COG0747	negative chemotaxis
AL549_RS01385	COG1609	Transcriptional regulator
AL549_RS01390	COG3842	ATPase activity
AL549_RS01400	COG0395	ABC-type sugar transport system, permease component
AL549_RS01415	COG1609	Transcriptional regulator
AL549_RS01435	COG2199	diguanylate cyclase activity
AL549_RS01445	COG0642	Histidine kinase
AL549_RS01455	COG0583	DNA-binding transcription factor activity
AL549_RS01465	COG0612	Peptidase, M16
AL549_RS01470	COG1283	sodium-dependent phosphate transmembrane transporter activity
AL549_RS01475	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AL549_RS01480	COG0625	glutathione transferase activity
AL549_RS01485	COG1012	belongs to the aldehyde dehydrogenase family
AL549_RS01540	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AL549_RS01545	COG0840	transmembrane signaling receptor activity
AL549_RS01555	COG1640	4-alpha-glucanotransferase
AL549_RS01560	COG0058	SHG alpha-glucan phosphorylase activity
AL549_RS01565	COG2909	trisaccharide binding
AL549_RS01580	COG1999	signal sequence binding
AL549_RS01585	COG2847	Copper chaperone PCu(A)C
AL549_RS01590	COG1162	GTPase activity
AL549_RS01595	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
AL549_RS01605	COG0531	amino acid
AL549_RS01610	COG1982	Orn Lys Arg decarboxylase major
AL549_RS01665	COG3706	GGDEF domain
AL549_RS01670	COG5001	Diguanylate cyclase
AL549_RS01680	COG1741	Belongs to the pirin family
AL549_RS01685	COG3123	guanosine phosphorylase activity
AL549_RS01705	COG1309	transcriptional regulator
AL549_RS01730	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AL549_RS01735	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AL549_RS01740	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AL549_RS01760	COG0189	ligase activity
AL549_RS01775	COG0363	glucosamine-6-phosphate deaminase activity
AL549_RS01785	COG0786	glutamate:sodium symporter activity
AL549_RS01790	COG0786	glutamate:sodium symporter activity
AL549_RS01810	COG3275	phosphorelay sensor kinase activity
AL549_RS01825	COG4591	ABC-type transport system involved in lipoprotein release permease component
AL549_RS01830	COG1136	(ABC) transporter
AL549_RS01840	COG0583	DNA-binding transcription factor activity
AL549_RS01850	COG0217	transcriptional regulatory protein
AL549_RS01870	COG3385	transposase activity
AL549_RS01875	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AL549_RS01875	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
AL549_RS01885	COG0444	Belongs to the ABC transporter superfamily
AL549_RS01890	COG4608	Belongs to the ABC transporter superfamily
AL549_RS01915	COG1444	tRNA N-acetyltransferase activity
AL549_RS01925	COG0745	RESPONSE REGULATOR receiver
AL549_RS01940	COG0835	chemotaxis
AL549_RS01945	COG0840	transmembrane signaling receptor activity
AL549_RS01950	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AL549_RS01955	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
AL549_RS01960	COG2201	protein-glutamate methylesterase activity
AL549_RS01965	COG0840	transmembrane signaling receptor activity
AL549_RS02010	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AL549_RS02015	COG0583	DNA-binding transcription factor activity
AL549_RS02025	COG0406	alpha-ribazole phosphatase activity
AL549_RS02030	COG2200	EAL domain
AL549_RS02030	COG2203	Gaf domain
AL549_RS02030	COG2199	diguanylate cyclase activity
AL549_RS02040	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL549_RS02040	COG1263	PTS System
AL549_RS02045	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AL549_RS02050	COG1737	Transcriptional regulator
AL549_RS02055	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AL549_RS02055	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AL549_RS02065	COG0110	maltose O-acetyltransferase activity
AL549_RS02070	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AL549_RS02075	COG0459	protein refolding
AL549_RS02110	COG2204	response regulator
AL549_RS02120	COG0259	pyridoxamine-phosphate oxidase activity
AL549_RS02145	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AL549_RS02160	COG5492	domain, Protein
AL549_RS02165	COG3119	arylsulfatase activity
AL549_RS02170	COG3119	arylsulfatase activity
AL549_RS02175	COG0641	radical SAM
AL549_RS02180	COG3119	arylsulfatase activity
AL549_RS02190	COG0747	negative chemotaxis
AL549_RS02195	COG0601	transmembrane transport
AL549_RS02200	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL549_RS02225	COG0659	secondary active sulfate transmembrane transporter activity
AL549_RS02230	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AL549_RS02240	COG1028	Short-chain dehydrogenase reductase Sdr
AL549_RS02250	COG5426	von Willebrand factor, type A
AL549_RS02255	COG5492	domain, Protein
AL549_RS02260	COG1132	(ABC) transporter
AL549_RS02275	COG3623	hexulose-6-phosphate isomerase
AL549_RS02280	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
AL549_RS02285	COG0561	phosphatase activity
AL549_RS02315	COG1902	pentaerythritol trinitrate reductase activity
AL549_RS02320	COG2999	glutathione oxidoreductase activity
AL549_RS02325	COG1028	Short-chain dehydrogenase reductase Sdr
AL549_RS02340	COG0800	Aldolase
AL549_RS02345	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL549_RS02350	COG1904	glucuronate isomerase
AL549_RS02355	COG0246	Mannitol dehydrogenase
AL549_RS02365	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AL549_RS02375	COG2186	Transcriptional regulator
AL549_RS02385	COG0513	Belongs to the DEAD box helicase family
AL549_RS02390	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AL549_RS02395	COG1757	Na H antiporter
AL549_RS02405	COG1335	isochorismatase
AL549_RS02415	COG0697	spore germination
AL549_RS02425	COG2258	MOSC domain
AL549_RS02445	COG1486	melibiose metabolic process
AL549_RS02450	COG0583	DNA-binding transcription factor activity
AL549_RS02470	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AL549_RS02485	COG0840	transmembrane signaling receptor activity
AL549_RS02505	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AL549_RS02510	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AL549_RS02535	COG2015	COG2015, Alkyl sulfatase and related hydrolases
AL549_RS02550	COG2207	Transcriptional regulator
AL549_RS02555	COG0697	spore germination
AL549_RS02560	COG1349	DNA-binding transcription factor activity
AL549_RS02565	COG1349	DNA-binding transcription factor activity
AL549_RS02575	COG2222	sugar isomerase
AL549_RS02580	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL549_RS02590	COG3716	PTS system mannose fructose sorbose family IID component
AL549_RS02595	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL549_RS02610	COG0488	(ABC) transporter
AL549_RS02630	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AL549_RS02635	COG1120	ATPase activity
AL549_RS02665	COG1136	(ABC) transporter
AL549_RS02665	COG0577	efflux transmembrane transporter activity
AL549_RS02670	COG1136	(ABC) transporter
AL549_RS02670	COG0577	efflux transmembrane transporter activity
AL549_RS02675	COG2176	DNA-directed DNA polymerase activity
AL549_RS02695	COG3706	GGDEF domain
AL549_RS02730	COG2205	protein histidine kinase activity
AL549_RS02745	COG2015	COG2015, Alkyl sulfatase and related hydrolases
AL549_RS02775	COG0579	oxidoreductase
AL549_RS02785	COG3437	response regulator, receiver
AL549_RS02805	COG1357	PFAM Pentapeptide repeats (8 copies)
AL549_RS02815	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AL549_RS02850	COG0513	Belongs to the DEAD box helicase family
AL549_RS02870	COG0583	DNA-binding transcription factor activity
AL549_RS02880	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AL549_RS02910	COG2814	Major facilitator Superfamily
AL549_RS02930	COG0583	DNA-binding transcription factor activity
AL549_RS02950	COG1858	cytochrome C peroxidase
AL549_RS02975	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AL549_RS02980	COG0454	-acetyltransferase
AL549_RS03000	COG2205	protein histidine kinase activity
AL549_RS03025	COG3046	protein related to deoxyribodipyrimidine photolyase
AL549_RS03030	COG2207	Transcriptional regulator
AL549_RS03035	COG1881	PFAM PEBP family protein
AL549_RS03040	COG0494	nUDIX hydrolase
AL549_RS03070	COG0668	transmembrane transport
AL549_RS03090	COG3153	acetyltransferase
AL549_RS03090	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AL549_RS03120	COG1028	Short-chain dehydrogenase reductase Sdr
AL549_RS03130	COG1917	Cupin 2, conserved barrel domain protein
AL549_RS03150	COG0697	spore germination
AL549_RS03155	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL549_RS03160	COG0800	Aldolase
AL549_RS03190	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AL549_RS03195	COG0823	Involved in the tonB-independent uptake of proteins
AL549_RS03200	COG0366	Alpha amylase catalytic
AL549_RS03210	COG3366	ferrous iron transmembrane transporter activity
AL549_RS03215	COG0700	Nucleoside recognition
AL549_RS03220	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AL549_RS03255	COG0640	Transcriptional regulator
AL549_RS03260	COG0798	PFAM Bile acid sodium symporter
AL549_RS03280	COG2194	sulfuric ester hydrolase activity
AL549_RS03285	COG0583	DNA-binding transcription factor activity
AL549_RS03295	COG2015	COG2015, Alkyl sulfatase and related hydrolases
AL549_RS03320	COG0673	inositol 2-dehydrogenase activity
AL549_RS03325	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AL549_RS03330	COG2197	response regulator
AL549_RS03335	COG0384	phenazine biosynthesis protein PhzF
AL549_RS03350	COG1879	ABC-type sugar transport system periplasmic component
AL549_RS03360	COG3284	Transcriptional regulator
AL549_RS03365	COG1012	belongs to the aldehyde dehydrogenase family
AL549_RS03375	COG1253	flavin adenine dinucleotide binding
AL549_RS03400	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL549_RS03405	COG1609	Transcriptional regulator
AL549_RS03425	COG0488	(ABC) transporter
AL549_RS03430	COG0814	amino acid
AL549_RS03435	COG3033	Beta-eliminating lyase
AL549_RS03445	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL549_RS03470	COG0189	ligase activity
AL549_RS03470	COG4067	protein conserved in archaea
AL549_RS03475	COG0189	ligase activity
AL549_RS03490	COG4774	siderophore transport
AL549_RS03490	COG1629	transport
AL549_RS03495	COG4607	ABC-type enterochelin transport system periplasmic component
AL549_RS03505	COG1021	2,3-dihydroxybenzoate-AMP ligase
AL549_RS03525	COG1021	2,3-dihydroxybenzoate-AMP ligase
AL549_RS03530	COG1169	isochorismate synthase
AL549_RS03535	COG1028	Short-chain dehydrogenase reductase Sdr
AL549_RS03540	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AL549_RS03555	COG2977	Belongs to the P-Pant transferase superfamily
AL549_RS03570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL549_RS03575	COG0840	transmembrane signaling receptor activity
AL549_RS03585	COG2755	lipolytic protein G-D-S-L family
AL549_RS03590	COG5001	Diguanylate cyclase
AL549_RS03590	COG5002	protein histidine kinase activity
AL549_RS03605	COG4160	amino acid transport
AL549_RS03610	COG4215	(ABC) transporter
AL549_RS03615	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL549_RS03620	COG1126	abc transporter atp-binding protein
AL549_RS03625	COG3015	lipoprotein NlpE involved in copper resistance
AL549_RS03640	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AL549_RS03680	COG2814	Major facilitator Superfamily
AL549_RS03705	COG1139	Iron-sulfur cluster binding protein
AL549_RS03715	COG1620	l-lactate permease
AL549_RS03720	COG0583	DNA-binding transcription factor activity
AL549_RS03725	COG1505	serine-type exopeptidase activity
AL549_RS03730	COG4172	Belongs to the ABC transporter superfamily
AL549_RS03745	COG0402	S-adenosylhomocysteine deaminase activity
AL549_RS03750	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AL549_RS03760	COG2239	Acts as a magnesium transporter
AL549_RS03785	COG0745	RESPONSE REGULATOR receiver
AL549_RS03790	COG2205	protein histidine kinase activity
AL549_RS03805	COG0121	glutamine amidotransferase
AL549_RS03810	COG0531	amino acid
AL549_RS03820	COG1522	sequence-specific DNA binding
AL549_RS03840	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AL549_RS03845	COG0583	DNA-binding transcription factor activity
AL549_RS03870	COG0784	Response regulator, receiver
AL549_RS03870	COG2205	protein histidine kinase activity
AL549_RS03870	COG5002	protein histidine kinase activity
AL549_RS03875	COG0534	Mate efflux family protein
AL549_RS03880	COG2926	Belongs to the UPF0265 family
AL549_RS03895	COG2827	Endonuclease containing a URI domain
AL549_RS03905	COG1879	ABC-type sugar transport system periplasmic component
AL549_RS03950	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AL549_RS03955	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AL549_RS03965	COG0183	Belongs to the thiolase family
AL549_RS03985	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AL549_RS03990	COG1940	carbohydrate kinase activity
AL549_RS03995	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
AL549_RS04000	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AL549_RS04005	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AL549_RS04010	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AL549_RS04015	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL549_RS04020	COG1737	Transcriptional regulator
AL549_RS04025	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
AL549_RS04035	COG3005	denitrification pathway
AL549_RS04045	COG0243	molybdopterin cofactor binding
AL549_RS04055	COG3850	Histidine kinase
AL549_RS04060	COG2197	response regulator
AL549_RS04080	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AL549_RS04080	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AL549_RS04090	COG0516	GMP reductase activity
AL549_RS04140	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AL549_RS04155	COG3568	Endonuclease Exonuclease Phosphatase
AL549_RS04180	COG0513	Belongs to the DEAD box helicase family
AL549_RS04190	COG2514	catechol 2,3-dioxygenase activity
AL549_RS04195	COG1846	Transcriptional regulator
AL549_RS04225	COG0842	Transport permease protein
AL549_RS04230	COG1131	(ABC) transporter
AL549_RS04240	COG0837	glucose binding
AL549_RS04240	COG1737	Transcriptional regulator
AL549_RS04250	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
AL549_RS04260	COG4145	pantothenate transmembrane transporter activity
AL549_RS04275	COG0251	oxidation-reduction process
AL549_RS04280	COG3706	GGDEF domain
AL549_RS04280	COG5001	Diguanylate cyclase
AL549_RS04280	COG2203	Gaf domain
AL549_RS04280	COG4251	negative regulation of phosphorylation
AL549_RS04285	COG0583	DNA-binding transcription factor activity
AL549_RS04290	COG2814	Major facilitator Superfamily
AL549_RS04305	COG0697	spore germination
AL549_RS04320	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AL549_RS04330	COG1764	response to oxidative stress
AL549_RS04335	COG1846	Transcriptional regulator
AL549_RS04360	COG1280	lysine exporter protein (LysE YggA)
AL549_RS04370	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AL549_RS04375	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AL549_RS04380	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AL549_RS04385	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
AL549_RS04410	COG1612	heme a metabolic process
AL549_RS04415	COG0109	protoheme IX farnesyltransferase activity
AL549_RS04420	COG2885	chlorophyll binding
AL549_RS04425	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AL549_RS04430	COG0840	transmembrane signaling receptor activity
AL549_RS04470	COG2897	thiosulfate sulfurtransferase activity
AL549_RS04475	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AL549_RS04480	COG0303	'Molybdopterin
AL549_RS04485	COG0302	gtp cyclohydrolase
AL549_RS04490	COG1914	H( )-stimulated, divalent metal cation uptake system
AL549_RS04500	COG0038	chloride channel
AL549_RS04520	COG4989	oxidoreductase activity
AL549_RS04530	COG2195	Cleaves the N-terminal amino acid of tripeptides
AL549_RS04550	COG0840	transmembrane signaling receptor activity
AL549_RS04555	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AL549_RS04560	COG0545	Peptidyl-prolyl cis-trans isomerase
AL549_RS04590	COG1278	Cold shock
AL549_RS04595	COG3036	rescue of stalled ribosome
AL549_RS04605	COG2203	Gaf domain
AL549_RS04605	COG2199	diguanylate cyclase activity
AL549_RS04615	COG1482	cell wall glycoprotein biosynthetic process
AL549_RS04620	COG2271	Major facilitator Superfamily
AL549_RS04625	COG3851	Histidine kinase
AL549_RS04630	COG2197	response regulator
AL549_RS04650	COG2130	NADP-dependent
AL549_RS04655	COG1309	transcriptional regulator
AL549_RS04670	COG1278	Cold shock
AL549_RS04675	COG3634	alkyl hydroperoxide reductase activity
AL549_RS04695	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AL549_RS04700	COG1960	acyl-CoA dehydrogenase activity
AL549_RS04710	COG0183	Belongs to the thiolase family
AL549_RS04720	COG1960	acyl-CoA dehydrogenase activity
AL549_RS04725	COG1024	Enoyl-CoA hydratase
AL549_RS04730	COG1024	Enoyl-CoA hydratase
AL549_RS04740	COG1028	Short-chain dehydrogenase reductase Sdr
AL549_RS04780	COG2994	toxin metabolic process
AL549_RS04785	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
AL549_RS04785	COG1073	alpha beta
AL549_RS04785	COG3064	Membrane
AL549_RS04840	COG0784	Response regulator, receiver
AL549_RS04840	COG3437	response regulator, receiver
AL549_RS04845	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL549_RS04845	COG4191	Histidine kinase
AL549_RS04855	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
AL549_RS04880	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AL549_RS04885	COG3186	Phenylalanine-4-hydroxylase
AL549_RS04890	COG2154	pterin-4-alpha-carbinolamine dehydratase
AL549_RS04910	COG3530	Putative quorum-sensing-regulated virulence factor
AL549_RS04930	COG2815	serine threonine protein kinase
AL549_RS04930	COG0515	serine threonine protein kinase
AL549_RS04965	COG0631	protein serine/threonine phosphatase activity
AL549_RS05055	COG3209	COG3209 Rhs family protein
AL549_RS05095	COG0501	Belongs to the peptidase M48B family
AL549_RS05100	COG1704	LemA family
AL549_RS05105	COG3069	C4-dicarboxylate transmembrane transporter activity
AL549_RS05115	COG0312	modulator of DNA gyrase
AL549_RS05120	COG0312	modulator of DNA gyrase
AL549_RS05125	COG0584	glycerophosphoryl diester phosphodiesterase
AL549_RS05130	COG2271	Major facilitator Superfamily
AL549_RS05145	COG0840	transmembrane signaling receptor activity
AL549_RS05150	COG0840	transmembrane signaling receptor activity
AL549_RS05155	COG0366	Alpha amylase catalytic
AL549_RS05160	COG0456	acetyltransferase
AL549_RS05165	COG0243	molybdopterin cofactor binding
AL549_RS05170	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AL549_RS05170	COG1648	precorrin-2 dehydrogenase activity
AL549_RS05185	COG3707	response regulator
AL549_RS05190	COG1116	anion transmembrane transporter activity
AL549_RS05190	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AL549_RS05195	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL549_RS05200	COG1116	anion transmembrane transporter activity
AL549_RS05205	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AL549_RS05205	COG2146	nitrite reductase [NAD(P)H] activity
AL549_RS05220	COG2199	diguanylate cyclase activity
AL549_RS05230	COG0523	cobalamin synthesis protein
AL549_RS05240	COG0513	Belongs to the DEAD box helicase family
AL549_RS05245	COG0010	Belongs to the arginase family
AL549_RS05255	COG5001	Diguanylate cyclase
AL549_RS05255	COG2203	Gaf domain
AL549_RS05255	COG4251	negative regulation of phosphorylation
AL549_RS05255	COG3706	GGDEF domain
AL549_RS05265	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AL549_RS05295	COG0840	transmembrane signaling receptor activity
AL549_RS05300	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AL549_RS05335	COG0811	peptide transport
AL549_RS05340	COG0811	peptide transport
AL549_RS05345	COG0848	biopolymer transport protein
AL549_RS05360	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AL549_RS05380	COG0534	Mate efflux family protein
AL549_RS05390	COG0477	Major facilitator Superfamily
AL549_RS05395	COG3118	belongs to the thioredoxin family
AL549_RS05400	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AL549_RS05455	COG1328	CTP reductase activity
AL549_RS05460	COG0602	queuosine metabolic process
AL549_RS05465	COG0840	transmembrane signaling receptor activity
AL549_RS05475	COG4067	protein conserved in archaea
AL549_RS05475	COG0189	ligase activity
AL549_RS05480	COG3385	transposase activity
AL549_RS05500	COG0725	ABC transporter, periplasmic molybdate-binding protein
AL549_RS05505	COG4149	molybdate abc transporter
AL549_RS05515	COG0697	spore germination
AL549_RS05520	COG1846	Transcriptional regulator
AL549_RS05530	COG2199	diguanylate cyclase activity
AL549_RS05540	COG3706	GGDEF domain
AL549_RS05555	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AL549_RS05560	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AL549_RS05570	COG0745	RESPONSE REGULATOR receiver
AL549_RS05590	COG0023	Translation Initiation Factor
AL549_RS05600	COG1181	Belongs to the D-alanine--D-alanine ligase family
AL549_RS05610	COG0045	succinate-CoA ligase (ADP-forming) activity
AL549_RS05610	COG1042	CoA-binding domain protein
AL549_RS05610	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AL549_RS05615	COG0583	DNA-binding transcription factor activity
AL549_RS05625	COG5002	protein histidine kinase activity
AL549_RS05625	COG5001	Diguanylate cyclase
AL549_RS05625	COG3447	MASE1 domain protein
AL549_RS05635	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AL549_RS05640	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AL549_RS05645	COG1984	allophanate hydrolase subunit 2
AL549_RS05650	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AL549_RS05650	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL549_RS05655	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AL549_RS05660	COG4181	ATPase activity
AL549_RS05670	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AL549_RS05675	COG1716	ATPase activity
AL549_RS05675	COG5001	Diguanylate cyclase
AL549_RS05690	COG0484	heat shock protein binding
AL549_RS05710	COG0583	DNA-binding transcription factor activity
AL549_RS05715	COG0366	Alpha amylase catalytic
AL549_RS05725	COG4533	DNA binding
AL549_RS05735	COG2050	protein possibly involved in aromatic compounds catabolism
AL549_RS05750	COG2067	long-chain fatty acid transport protein
AL549_RS05755	COG2267	carboxylic ester hydrolase activity
AL549_RS05785	COG0861	Integral membrane protein TerC family
AL549_RS05790	COG0737	Belongs to the 5'-nucleotidase family
AL549_RS05795	COG3593	DNA synthesis involved in DNA repair
AL549_RS05805	COG0583	DNA-binding transcription factor activity
AL549_RS05810	COG2116	formate transmembrane transporter activity
AL549_RS05815	COG2353	YceI-like domain
AL549_RS05820	COG3038	cytochrome b561
AL549_RS05835	COG0513	Belongs to the DEAD box helicase family
AL549_RS05850	COG0546	phosphoglycolate phosphatase activity
AL549_RS05855	COG0784	Response regulator, receiver
AL549_RS05855	COG3437	response regulator, receiver
AL549_RS05870	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL549_RS05890	COG2207	Transcriptional regulator
AL549_RS05895	COG1979	alcohol dehydrogenase
AL549_RS05905	COG4191	Histidine kinase
AL549_RS05915	COG2271	Major facilitator Superfamily
AL549_RS05920	COG0469	pyruvate kinase activity
AL549_RS05945	COG1609	Transcriptional regulator
AL549_RS05950	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL549_RS05950	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL549_RS05955	COG1105	Belongs to the carbohydrate kinase PfkB family
AL549_RS05960	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL549_RS05960	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
AL549_RS05960	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL549_RS06005	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AL549_RS06010	COG0509	glycine decarboxylation via glycine cleavage system
AL549_RS06015	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AL549_RS06015	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AL549_RS06035	COG1132	(ABC) transporter
AL549_RS06045	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AL549_RS06075	COG2814	Major facilitator Superfamily
AL549_RS06105	COG0641	radical SAM
AL549_RS06115	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
AL549_RS06150	COG0714	Associated with various cellular activities
AL549_RS06155	COG0641	radical SAM
AL549_RS06160	COG3119	arylsulfatase activity
AL549_RS06170	COG3119	arylsulfatase activity
AL549_RS06175	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AL549_RS06180	COG0513	Belongs to the DEAD box helicase family
AL549_RS06185	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
AL549_RS06200	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AL549_RS06225	COG5001	Diguanylate cyclase
AL549_RS06225	COG1716	ATPase activity
AL549_RS06230	COG0784	Response regulator, receiver
AL549_RS06230	COG2205	protein histidine kinase activity
AL549_RS06235	COG0513	Belongs to the DEAD box helicase family
AL549_RS06260	COG3005	denitrification pathway
AL549_RS06265	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AL549_RS06290	COG1879	ABC-type sugar transport system periplasmic component
AL549_RS06295	COG1803	Methylglyoxal synthase
AL549_RS06300	COG0210	DNA helicase
AL549_RS06305	COG1289	transmembrane transporter activity
AL549_RS06335	COG0789	Transcriptional regulator
AL549_RS06340	COG4604	ABC transporter, ATP-binding protein
AL549_RS06345	COG4605	iron ion homeostasis
AL549_RS06350	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL549_RS06365	COG0110	maltose O-acetyltransferase activity
AL549_RS06375	COG3290	protein histidine kinase activity
AL549_RS06380	COG0471	metal ion transport
AL549_RS06465	COG4964	Belongs to the GSP D family
AL549_RS06485	COG0583	DNA-binding transcription factor activity
AL549_RS06495	COG0419	ATPase involved in DNA repair
AL549_RS06500	COG0420	3'-5' exonuclease activity
AL549_RS06515	COG0456	acetyltransferase
AL549_RS06525	COG0784	Response regulator, receiver
AL549_RS06525	COG0835	chemotaxis
AL549_RS06530	COG1609	Transcriptional regulator
AL549_RS06535	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL549_RS06540	COG1879	ABC-type sugar transport system periplasmic component
AL549_RS06545	COG1172	Belongs to the binding-protein-dependent transport system permease family
AL549_RS06550	COG1129	ABC transporter
AL549_RS06555	COG1869	D-ribose catabolic process
AL549_RS06570	COG2315	Protein conserved in bacteria
AL549_RS06575	COG2425	protein containing a von Willebrand factor type A (vWA) domain
AL549_RS06590	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
AL549_RS06605	COG1288	antiporter activity
AL549_RS06615	COG0671	phosphoesterase, PA-phosphatase related
AL549_RS06630	COG2962	Rard protein
AL549_RS06655	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AL549_RS06660	COG0814	amino acid
AL549_RS06685	COG3174	membrane
AL549_RS06690	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL549_RS06720	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AL549_RS06725	COG0443	Heat shock 70 kDa protein
AL549_RS06730	COG1454	alcohol dehydrogenase
AL549_RS06740	COG2133	pyrroloquinoline quinone binding
AL549_RS06745	COG1619	proteins homologs of microcin C7 resistance protein MccF
AL549_RS06760	COG0247	lactate metabolic process
AL549_RS06770	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AL549_RS06790	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AL549_RS06800	COG3059	membrane
AL549_RS06805	COG4175	Glycine betaine
AL549_RS06825	COG1012	belongs to the aldehyde dehydrogenase family
AL549_RS06830	COG1309	transcriptional regulator
AL549_RS06850	COG1686	Belongs to the peptidase S11 family
AL549_RS06870	COG1760	l-serine dehydratase
AL549_RS06875	COG3104	oligopeptide transport
AL549_RS06885	COG0583	DNA-binding transcription factor activity
AL549_RS06890	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL549_RS06910	COG3842	ATPase activity
AL549_RS06920	COG1840	ABC-type Fe3 transport system, periplasmic component
AL549_RS06925	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AL549_RS06930	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AL549_RS06935	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AL549_RS06940	COG2207	Transcriptional regulator
AL549_RS06940	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AL549_RS06945	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL549_RS06970	COG1011	Hydrolase
AL549_RS06995	COG1765	OsmC-like protein
AL549_RS07000	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AL549_RS07000	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AL549_RS07005	COG3706	GGDEF domain
AL549_RS07020	COG0840	transmembrane signaling receptor activity
AL549_RS07040	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AL549_RS07065	COG2084	Dehydrogenase
AL549_RS07075	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AL549_RS07085	COG0739	heme binding
AL549_RS07100	COG3314	Sporulation integral membrane protein YlbJ
AL549_RS07115	COG0840	transmembrane signaling receptor activity
AL549_RS07125	COG0366	Alpha amylase catalytic
AL549_RS07130	COG0589	response to stress
AL549_RS07135	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AL549_RS07140	COG0835	chemotaxis
AL549_RS07140	COG0784	Response regulator, receiver
AL549_RS07150	COG0748	coenzyme F420 binding
AL549_RS07155	COG3721	Heme iron utilization protein
AL549_RS07165	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
AL549_RS07170	COG0811	peptide transport
AL549_RS07175	COG0848	biopolymer transport protein
AL549_RS07185	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL549_RS07190	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AL549_RS07690	COG2205	protein histidine kinase activity
AL549_RS07690	COG0784	Response regulator, receiver
AL549_RS08550	COG1609	Transcriptional regulator
AL549_RS08755	COG3842	ATPase activity
AL549_RS08775	COG2723	6-phospho-beta-galactosidase activity
AL549_RS08910	COG0625	glutathione transferase activity
AL549_RS09455	COG0840	transmembrane signaling receptor activity
AL549_RS10645	COG0784	Response regulator, receiver
AL549_RS10645	COG2205	protein histidine kinase activity
AL549_RS10810	COG0823	Involved in the tonB-independent uptake of proteins
AL549_RS11085	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL549_RS11195	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AL549_RS11315	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AL549_RS11755	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AL549_RS11755	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AL549_RS11895	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AL549_RS12000	COG2771	luxR family
AL549_RS12000	COG2200	EAL domain
AL549_RS12310	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
AL549_RS12310	COG3064	Membrane
AL549_RS12310	COG1073	alpha beta
AL549_RS12330	COG1073	alpha beta
AL549_RS12330	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
AL549_RS12330	COG3064	Membrane
AL549_RS12690	COG0501	Belongs to the peptidase M48B family
AL549_RS12740	COG2271	Major facilitator Superfamily
AL549_RS13185	COG0446	pyridine nucleotide-disulphide oxidoreductase
AL549_RS13755	COG0513	Belongs to the DEAD box helicase family
AL549_RS13805	COG3437	response regulator, receiver
AL549_RS13805	COG0784	Response regulator, receiver
AL549_RS13945	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL549_RS13945	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL549_RS13945	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
AL549_RS13950	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL549_RS13950	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL549_RS13950	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
AL549_RS14575	COG1172	Belongs to the binding-protein-dependent transport system permease family
AL549_RS14955	COG2207	Transcriptional regulator
AL549_RS14955	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AL549_RS15205	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AL549_RS15415	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AL549_RS15435	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AL549_RS15455	COG0070	glutamate synthase
AL549_RS15455	COG0067	glutamate synthase
AL549_RS15455	COG0069	glutamate synthase activity
AL549_RS15590	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AL549_RS15745	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AL549_RS16065	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AL549_RS16090	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AL549_RS16145	COG0517	IMP dehydrogenase activity
AL549_RS16145	COG0516	GMP reductase activity
AL549_RS16265	COG0497	DNA recombination
AL549_RS16750	COG2912	Transglutaminase-like superfamily
AL549_RS16850	COG3385	transposase activity
AL549_RS17065	COG1940	carbohydrate kinase activity
AL549_RS17065	COG1846	Transcriptional regulator
AL549_RS17070	COG1940	carbohydrate kinase activity
AL549_RS17070	COG1846	Transcriptional regulator
AL549_RS17325	COG2986	histidine ammonia-lyase
AL549_RS17405	COG1653	transport
AL549_RS18055	COG4657	Part of a membrane complex involved in electron transport
AL549_RS18340	COG1138	Cytochrome C-type biogenesis protein
AL549_RS18385	COG1530	ribonuclease E activity
AL549_RS18395	COG1530	ribonuclease E activity
AL549_RS18465	COG0733	neurotransmitter:sodium symporter activity
AL549_RS19125	COG0733	neurotransmitter:sodium symporter activity
AL549_RS19170	COG3604	Transcriptional regulator
AL549_RS19290	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AL549_RS19315	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AL549_RS19345	COG0076	glutamate decarboxylase activity
AL549_RS19385	COG4191	Histidine kinase
AL549_RS19440	COG0471	metal ion transport
AL549_RS19480	COG1643	Atp-dependent helicase
AL549_RS20435	COG2902	Dehydrogenase
AL549_RS20465	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AL549_RS20465	COG0116	Belongs to the methyltransferase superfamily
AL549_RS20625	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AL549_RS20725	COG0840	transmembrane signaling receptor activity
AL549_RS20735	COG0488	(ABC) transporter
AL549_RS21935	COG2986	histidine ammonia-lyase
AL549_RS21970	COG0277	FAD linked oxidase domain protein
AL549_RS21970	COG0247	lactate metabolic process
AL549_RS22025	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AL549_RS22175	COG1643	Atp-dependent helicase
AL549_RS22180	COG1643	Atp-dependent helicase