locus-tag	class	description
FORC37_RS00010	COG0592	DNA-directed DNA polymerase activity
FORC37_RS00020	COG0187	DNA topoisomerase II activity
FORC37_RS00025	COG0071	Belongs to the small heat shock protein (HSP20) family
FORC37_RS00035	COG3977	Valine--pyruvate aminotransferase
FORC37_RS00045	COG0751	glycine-tRNA ligase activity
FORC37_RS00050	COG0752	glycyl-tRNA synthetase alpha subunit
FORC37_RS00055	COG2119	membrane
FORC37_RS00065	COG0425	Belongs to the sulfur carrier protein TusA family
FORC37_RS00080	COG0604	alcohol dehydrogenase
FORC37_RS00085	COG0183	Belongs to the thiolase family
FORC37_RS00095	COG1739	Uncharacterized protein family UPF0029
FORC37_RS00100	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FORC37_RS00105	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
FORC37_RS00140	COG2132	Multicopper oxidase
FORC37_RS00145	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FORC37_RS00150	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FORC37_RS00160	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FORC37_RS00170	COG2022	thiamine diphosphate biosynthetic process
FORC37_RS00180	COG0006	proline dipeptidase activity
FORC37_RS00180	COG0006	proline dipeptidase activity
FORC37_RS00220	COG0210	DNA helicase
FORC37_RS00225	COG1280	lysine exporter protein (LysE YggA)
FORC37_RS00235	COG2962	Rard protein
FORC37_RS00240	COG0514	ATP-dependent DNA helicase (RecQ)
FORC37_RS00250	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FORC37_RS00255	COG0248	Ppx GppA phosphatase
FORC37_RS00265	COG3118	belongs to the thioredoxin family
FORC37_RS00350	COG3335	DDE superfamily endonuclease
FORC37_RS00370	COG1322	Protein conserved in bacteria
FORC37_RS00375	COG2226	methyltransferase
FORC37_RS00380	COG3165	ubiquinone biosynthetic process from chorismate
FORC37_RS00390	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FORC37_RS00395	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FORC37_RS00400	COG0805	protein transport
FORC37_RS00405	COG0084	hydrolase, TatD family'
FORC37_RS00415	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FORC37_RS00415	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FORC37_RS00420	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FORC37_RS00450	COG5001	Diguanylate cyclase
FORC37_RS00450	COG3300	MHYT domain
FORC37_RS00460	COG3852	Histidine kinase
FORC37_RS00470	COG0174	glutamine synthetase
FORC37_RS00475	COG1217	gtp-binding protein TYPA
FORC37_RS00495	COG1295	ribonuclease BN
FORC37_RS00500	COG1490	D-aminoacyl-tRNA deacylase activity
FORC37_RS00505	COG0456	acetyltransferase
FORC37_RS00520	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FORC37_RS00525	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FORC37_RS00530	COG3031	protein transport across the cell outer membrane
FORC37_RS00540	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FORC37_RS00545	COG1459	type II secretion system
FORC37_RS00550	COG2165	general secretion pathway protein
FORC37_RS00555	COG2165	general secretion pathway protein
FORC37_RS00560	COG2165	general secretion pathway protein
FORC37_RS00565	COG4795	General secretion pathway protein
FORC37_RS00570	COG3156	type II secretion system protein K
FORC37_RS00575	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
FORC37_RS00580	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
FORC37_RS00590	COG1218	3'(2'),5'-bisphosphate nucleotidase
FORC37_RS00595	COG0494	nUDIX hydrolase
FORC37_RS00600	COG0316	Belongs to the HesB IscA family
FORC37_RS00600	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FORC37_RS00610	COG0596	Alpha beta hydrolase
FORC37_RS00620	COG3344	reverse transcriptase
FORC37_RS00625	COG2183	response to ionizing radiation
FORC37_RS00645	COG2233	PERMEase
FORC37_RS00650	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FORC37_RS00655	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FORC37_RS00660	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FORC37_RS00665	COG1758	RNA polymerase activity
FORC37_RS00670	COG0194	GDP metabolic process
FORC37_RS00685	COG0848	biopolymer transport protein
FORC37_RS00690	COG0811	peptide transport
FORC37_RS00695	COG0811	peptide transport
FORC37_RS00705	COG4206	TonB-dependent receptor
FORC37_RS00710	COG4174	ABC transporter (Permease)
FORC37_RS00715	COG4239	(ABC) transporter, permease
FORC37_RS00720	COG0747	negative chemotaxis
FORC37_RS00725	COG0444	Belongs to the ABC transporter superfamily
FORC37_RS00730	COG4608	Belongs to the ABC transporter superfamily
FORC37_RS00760	COG1561	YicC-like family, N-terminal region
FORC37_RS00765	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FORC37_RS00775	COG1560	Kdo2-lipid A biosynthetic process
FORC37_RS00780	COG1309	transcriptional regulator
FORC37_RS00795	COG2003	Belongs to the UPF0758 family
FORC37_RS00800	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FORC37_RS00805	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FORC37_RS00815	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FORC37_RS00825	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FORC37_RS00830	COG0859	PFAM glycosyl transferase family 9
FORC37_RS00835	COG0463	Glycosyl transferase, family 2
FORC37_RS00840	COG0859	PFAM glycosyl transferase family 9
FORC37_RS00845	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FORC37_RS00850	COG3642	lipopolysaccharide core region biosynthetic process
FORC37_RS00855	COG3083	sulfuric ester hydrolase activity
FORC37_RS00875	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FORC37_RS00880	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FORC37_RS00885	COG2089	acid synthase
FORC37_RS00905	COG1083	cytidylyl-transferase
FORC37_RS00910	COG1028	Short-chain dehydrogenase reductase Sdr
FORC37_RS00925	COG0318	PFAM AMP-dependent synthetase and ligase
FORC37_RS00955	COG1519	Transferase
FORC37_RS00960	COG0859	PFAM glycosyl transferase family 9
FORC37_RS00965	COG1560	Kdo2-lipid A biosynthetic process
FORC37_RS00975	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FORC37_RS01025	COG1596	polysaccharide export
FORC37_RS01045	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FORC37_RS01090	COG0438	transferase activity, transferring glycosyl groups
FORC37_RS01095	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FORC37_RS01105	COG2030	dehydratase
FORC37_RS01110	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FORC37_RS01120	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FORC37_RS01150	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FORC37_RS01165	COG3064	Membrane
FORC37_RS01190	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FORC37_RS01195	COG0088	Forms part of the polypeptide exit tunnel
FORC37_RS01200	COG0089	rRNA binding
FORC37_RS01205	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FORC37_RS01210	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FORC37_RS01220	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FORC37_RS01225	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FORC37_RS01230	COG0255	Belongs to the universal ribosomal protein uL29 family
FORC37_RS01235	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FORC37_RS01240	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FORC37_RS01245	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FORC37_RS01250	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FORC37_RS01255	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FORC37_RS01260	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FORC37_RS01265	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FORC37_RS01270	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FORC37_RS01275	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FORC37_RS01280	COG1841	ribosomal large subunit assembly
FORC37_RS01285	COG0200	Binds to the 23S rRNA
FORC37_RS01290	COG0201	protein transport
FORC37_RS01295	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FORC37_RS01300	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FORC37_RS01305	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FORC37_RS01310	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FORC37_RS01315	COG0202	RNA polymerase activity
FORC37_RS01320	COG0203	ribosomal protein L17
FORC37_RS01330	COG0545	Peptidyl-prolyl cis-trans isomerase
FORC37_RS01335	COG3266	domain, Protein
FORC37_RS01335	COG3061	Opacity-associated protein A
FORC37_RS01345	COG2153	protein acetylation
FORC37_RS01355	COG0737	Belongs to the 5'-nucleotidase family
FORC37_RS01360	COG1648	precorrin-2 dehydrogenase activity
FORC37_RS01360	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FORC37_RS01365	COG0175	sulfate reduction
FORC37_RS01370	COG2895	sulfate adenylyltransferase (ATP) activity
FORC37_RS01375	COG3273	potassium ion transport
FORC37_RS01375	COG0471	metal ion transport
FORC37_RS01380	COG0529	Catalyzes the synthesis of activated sulfate
FORC37_RS01400	COG1136	(ABC) transporter
FORC37_RS01400	COG0577	efflux transmembrane transporter activity
FORC37_RS01415	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
FORC37_RS01430	COG0729	surface antigen
FORC37_RS01435	COG2911	Protein conserved in bacteria
FORC37_RS01440	COG2105	PFAM AIG2 family protein
FORC37_RS01450	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FORC37_RS01455	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
FORC37_RS01460	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FORC37_RS01465	COG0163	prenyltransferase activity
FORC37_RS01470	COG4143	(ABC) transporter
FORC37_RS01475	COG1178	ABC-type Fe3 transport system permease component
FORC37_RS01480	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FORC37_RS01485	COG3028	Belongs to the UPF0307 family
FORC37_RS01490	COG0312	modulator of DNA gyrase
FORC37_RS01495	COG2239	Acts as a magnesium transporter
FORC37_RS01500	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC37_RS01505	COG1660	Displays ATPase and GTPase activities
FORC37_RS01510	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC37_RS01515	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FORC37_RS01525	COG1137	ATPase activity
FORC37_RS01530	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FORC37_RS01540	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FORC37_RS01545	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FORC37_RS01545	COG0517	IMP dehydrogenase activity
FORC37_RS01555	COG1127	ABC transporter
FORC37_RS01560	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FORC37_RS01565	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FORC37_RS01570	COG2854	intermembrane phospholipid transfer
FORC37_RS01580	COG5007	Belongs to the BolA IbaG family
FORC37_RS01590	COG0204	Acyl-transferase
FORC37_RS01595	COG0589	response to stress
FORC37_RS01605	COG2358	TRAP transporter, solute receptor (TAXI family
FORC37_RS01610	COG1438	arginine binding
FORC37_RS01615	COG0039	L-malate dehydrogenase activity
FORC37_RS01620	COG0142	geranyltranstransferase activity
FORC37_RS01625	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FORC37_RS01630	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FORC37_RS01640	COG2966	Psort location CytoplasmicMembrane, score
FORC37_RS01645	COG3610	response to peptide
FORC37_RS01660	COG2967	ApaG domain
FORC37_RS01665	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FORC37_RS01670	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FORC37_RS01695	COG0066	3-isopropylmalate dehydratase activity
FORC37_RS01705	COG0473	3-isopropylmalate dehydrogenase activity
FORC37_RS01710	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FORC37_RS01735	COG1022	Amp-dependent synthetase and ligase
FORC37_RS01740	COG0028	Belongs to the TPP enzyme family
FORC37_RS01745	COG0440	acetolactate synthase activity
FORC37_RS01750	COG3706	GGDEF domain
FORC37_RS01770	COG1349	DNA-binding transcription factor activity
FORC37_RS01775	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FORC37_RS01780	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FORC37_RS01795	COG3550	peptidyl-serine autophosphorylation
FORC37_RS01820	COG1610	YqeY-like protein
FORC37_RS01825	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FORC37_RS01830	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FORC37_RS01835	COG0596	Alpha beta hydrolase
FORC37_RS01845	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FORC37_RS01850	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FORC37_RS01855	COG1968	undecaprenyl-diphosphatase activity
FORC37_RS01860	COG0617	tRNA 3'-terminal CCA addition
FORC37_RS01865	COG3409	Peptidoglycan-binding domain 1 protein
FORC37_RS01865	COG3267	Type II secretory pathway component ExeA
FORC37_RS01870	COG4991	sh3 domain protein
FORC37_RS01875	COG0306	phosphate transporter
FORC37_RS01880	COG1392	Phosphate transport regulator
FORC37_RS01885	COG3025	triphosphatase activity
FORC37_RS01890	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FORC37_RS01900	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FORC37_RS01910	COG1538	Outer membrane efflux protein
FORC37_RS01915	COG0494	nUDIX hydrolase
FORC37_RS01920	COG3151	Protein conserved in bacteria
FORC37_RS01930	COG3150	esterase
FORC37_RS01945	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FORC37_RS01950	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FORC37_RS01955	COG3105	Protein conserved in bacteria
FORC37_RS01960	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FORC37_RS01970	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FORC37_RS01975	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FORC37_RS01980	COG0723	plastoquinol--plastocyanin reductase activity
FORC37_RS01985	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FORC37_RS01990	COG2857	Cytochrome c1
FORC37_RS01995	COG0625	glutathione transferase activity
FORC37_RS02000	COG2969	positive regulation of protein catabolic process
FORC37_RS02005	COG2823	Periplasmic or secreted lipoprotein
FORC37_RS02010	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FORC37_RS02015	COG0792	nuclease activity
FORC37_RS02020	COG3107	peptidoglycan biosynthetic process
FORC37_RS02025	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FORC37_RS02035	COG0275	rRNA processing
FORC37_RS02040	COG3116	cell division
FORC37_RS02045	COG0768	penicillin binding
FORC37_RS02055	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FORC37_RS02060	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FORC37_RS02070	COG0772	Belongs to the SEDS family
FORC37_RS02080	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FORC37_RS02085	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FORC37_RS02090	COG0849	cell division
FORC37_RS02095	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FORC37_RS02100	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
FORC37_RS02110	COG0653	protein targeting
FORC37_RS02115	COG0494	nUDIX hydrolase
FORC37_RS02125	COG0505	Belongs to the CarA family
FORC37_RS02130	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FORC37_RS02140	COG0730	response to heat
FORC37_RS02145	COG0583	DNA-binding transcription factor activity
FORC37_RS02150	COG2860	membrane
FORC37_RS02155	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FORC37_RS02165	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FORC37_RS02175	COG0493	'glutamate synthase
FORC37_RS02180	COG0069	glutamate synthase activity
FORC37_RS02180	COG0067	glutamate synthase
FORC37_RS02180	COG0070	glutamate synthase
FORC37_RS02190	COG0067	glutamate synthase
FORC37_RS02190	COG0069	glutamate synthase activity
FORC37_RS02190	COG0070	glutamate synthase
FORC37_RS02195	COG1242	4 iron, 4 sulfur cluster binding
FORC37_RS02200	COG3706	GGDEF domain
FORC37_RS02200	COG4251	negative regulation of phosphorylation
FORC37_RS02200	COG5001	Diguanylate cyclase
FORC37_RS02200	COG2203	Gaf domain
FORC37_RS02205	COG0784	Response regulator, receiver
FORC37_RS02205	COG2198	Histidine kinase
FORC37_RS02205	COG5002	protein histidine kinase activity
FORC37_RS02215	COG0745	RESPONSE REGULATOR receiver
FORC37_RS02225	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FORC37_RS02240	COG0083	homoserine kinase activity
FORC37_RS02245	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FORC37_RS02250	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
FORC37_RS02260	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FORC37_RS02275	COG1115	amino acid carrier protein
FORC37_RS02280	COG3022	response to hydroperoxide
FORC37_RS02285	COG0513	Belongs to the DEAD box helicase family
FORC37_RS02305	COG4974	Belongs to the 'phage' integrase family
FORC37_RS02310	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FORC37_RS02315	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FORC37_RS02325	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FORC37_RS02340	COG0667	Aldo Keto reductase
FORC37_RS02350	COG3066	DNA modification
FORC37_RS02355	COG0494	nUDIX hydrolase
FORC37_RS02365	COG0730	response to heat
FORC37_RS02385	COG1283	sodium-dependent phosphate transmembrane transporter activity
FORC37_RS02390	COG0583	DNA-binding transcription factor activity
FORC37_RS02395	COG0640	Transcriptional regulator
FORC37_RS02400	COG0268	Binds directly to 16S ribosomal RNA
FORC37_RS02405	COG0728	peptidoglycan biosynthetic process
FORC37_RS02410	COG0196	riboflavin kinase activity
FORC37_RS02415	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FORC37_RS02420	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FORC37_RS02425	COG1047	Peptidyl-prolyl cis-trans
FORC37_RS02430	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FORC37_RS02440	COG3275	phosphorelay sensor kinase activity
FORC37_RS02445	COG1966	Carbon starvation protein
FORC37_RS02465	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FORC37_RS02480	COG0287	Prephenate dehydrogenase
FORC37_RS02480	COG1605	Chorismate mutase
FORC37_RS02485	COG0739	heme binding
FORC37_RS02495	COG0488	(ABC) transporter
FORC37_RS02505	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
FORC37_RS02510	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
FORC37_RS02515	COG1605	Chorismate mutase
FORC37_RS02515	COG0077	Prephenate dehydratase
FORC37_RS02520	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FORC37_RS02525	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FORC37_RS02540	COG0542	response to heat
FORC37_RS02580	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FORC37_RS02585	COG0826	peptidase U32
FORC37_RS02595	COG0745	RESPONSE REGULATOR receiver
FORC37_RS02600	COG5002	protein histidine kinase activity
FORC37_RS02610	COG0248	Ppx GppA phosphatase
FORC37_RS02615	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FORC37_RS02620	COG0573	inorganic phosphate transmembrane transporter activity
FORC37_RS02625	COG0581	inorganic phosphate transmembrane transporter activity
FORC37_RS02630	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FORC37_RS02635	COG0704	Plays a role in the regulation of phosphate uptake
FORC37_RS02670	COG0450	alkyl hydroperoxide reductase
FORC37_RS02675	COG0583	DNA-binding transcription factor activity
FORC37_RS02680	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FORC37_RS02690	COG0517	IMP dehydrogenase activity
FORC37_RS02700	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FORC37_RS02705	COG0343	queuine tRNA-ribosyltransferase activity
FORC37_RS02710	COG1862	Preprotein translocase
FORC37_RS02715	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FORC37_RS02720	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FORC37_RS02735	COG0483	inositol monophosphate 1-phosphatase activity
FORC37_RS02740	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
FORC37_RS02745	COG1959	2 iron, 2 sulfur cluster binding
FORC37_RS02755	COG0822	iron-sulfur transferase activity
FORC37_RS02760	COG0316	Belongs to the HesB IscA family
FORC37_RS02770	COG0443	Heat shock 70 kDa protein
FORC37_RS02775	COG0633	Ferredoxin
FORC37_RS02780	COG2975	iron-sulfur cluster assembly
FORC37_RS02785	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FORC37_RS02790	COG0105	UTP biosynthetic process
FORC37_RS02805	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FORC37_RS02810	COG0124	histidyl-tRNA synthetase
FORC37_RS02815	COG2976	Protein conserved in bacteria
FORC37_RS02820	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FORC37_RS02835	COG2199	diguanylate cyclase activity
FORC37_RS02835	COG2203	Gaf domain
FORC37_RS02845	COG1570	exodeoxyribonuclease VII activity
FORC37_RS02850	COG0516	GMP reductase activity
FORC37_RS02850	COG0517	IMP dehydrogenase activity
FORC37_RS02855	COG0519	Catalyzes the synthesis of GMP from XMP
FORC37_RS02855	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FORC37_RS02865	COG1584	GPR1 FUN34 yaaH family protein
FORC37_RS02870	COG1115	amino acid carrier protein
FORC37_RS02880	COG0583	DNA-binding transcription factor activity
FORC37_RS02900	COG0009	L-threonylcarbamoyladenylate synthase
FORC37_RS02940	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FORC37_RS02945	COG2867	negative regulation of translational initiation
FORC37_RS02950	COG2914	Belongs to the UPF0125 (RnfH) family
FORC37_RS02955	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FORC37_RS02960	COG0497	DNA recombination
FORC37_RS02965	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FORC37_RS02970	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FORC37_RS03000	COG0443	Heat shock 70 kDa protein
FORC37_RS03005	COG0484	heat shock protein binding
FORC37_RS03010	COG3344	reverse transcriptase
FORC37_RS03040	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
FORC37_RS03045	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FORC37_RS03050	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FORC37_RS03055	COG0583	DNA-binding transcription factor activity
FORC37_RS03070	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FORC37_RS03100	COG2195	Cleaves the N-terminal amino acid of tripeptides
FORC37_RS03105	COG2252	PERMEase
FORC37_RS03110	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
FORC37_RS03115	COG1073	alpha beta
FORC37_RS03125	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FORC37_RS03135	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FORC37_RS03140	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FORC37_RS03140	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FORC37_RS03155	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FORC37_RS03160	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FORC37_RS03165	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FORC37_RS03170	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FORC37_RS03180	COG0142	geranyltranstransferase activity
FORC37_RS03185	COG1722	exodeoxyribonuclease VII activity
FORC37_RS03190	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FORC37_RS03205	COG0583	DNA-binding transcription factor activity
FORC37_RS03215	COG2363	Small membrane protein
FORC37_RS03230	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FORC37_RS03235	COG1611	Belongs to the LOG family
FORC37_RS03250	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FORC37_RS03250	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FORC37_RS03260	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
FORC37_RS03265	COG1464	Belongs to the NlpA lipoprotein family
FORC37_RS03270	COG2011	ABC-type metal ion transport system permease component
FORC37_RS03275	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FORC37_RS03280	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FORC37_RS03290	COG1263	PTS System
FORC37_RS03290	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC37_RS03295	COG0366	Alpha amylase catalytic
FORC37_RS03325	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FORC37_RS03335	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FORC37_RS03340	COG0321	lipoyl(octanoyl) transferase activity
FORC37_RS03345	COG2921	Belongs to the UPF0250 family
FORC37_RS03350	COG1686	Belongs to the peptidase S11 family
FORC37_RS03355	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FORC37_RS03360	COG0772	Belongs to the SEDS family
FORC37_RS03365	COG0768	penicillin binding
FORC37_RS03370	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FORC37_RS03375	COG0799	negative regulation of ribosome biogenesis
FORC37_RS03380	COG1466	dna polymerase III delta subunit
FORC37_RS03385	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
FORC37_RS03390	COG0495	leucyl-tRNA aminoacylation
FORC37_RS03395	COG2888	peptidyl-tyrosine sulfation
FORC37_RS03405	COG4535	Mg2 and Co2 transporter CorC
FORC37_RS03410	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FORC37_RS03415	COG1702	phosphate starvation-inducible protein PhoH
FORC37_RS03420	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FORC37_RS03425	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FORC37_RS03515	COG0193	aminoacyl-tRNA hydrolase activity
FORC37_RS03520	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FORC37_RS03525	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FORC37_RS03540	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FORC37_RS03545	COG2890	protein-(glutamine-N5) methyltransferase activity
FORC37_RS03555	COG2912	Transglutaminase-like superfamily
FORC37_RS03560	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FORC37_RS03575	COG1187	pseudouridine synthase activity
FORC37_RS03580	COG2840	Smr protein MutS2
FORC37_RS03600	COG3735	TraB family
FORC37_RS03615	COG2217	Heavy metal translocating P-type atpase
FORC37_RS03615	COG2608	mercury ion transmembrane transporter activity
FORC37_RS03675	COG0835	chemotaxis
FORC37_RS03675	COG0784	Response regulator, receiver
FORC37_RS03680	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FORC37_RS03685	COG1815	bacterial-type flagellum-dependent cell motility
FORC37_RS03700	COG1749	Flagellar hook protein flgE
FORC37_RS03705	COG4787	bacterial-type flagellum-dependent cell motility
FORC37_RS03720	COG1706	bacterial-type flagellum-dependent cell motility
FORC37_RS03725	COG3951	Flagellar rod assembly protein muramidase FlgJ
FORC37_RS03725	COG1705	Flagellar rod assembly protein muramidase FlgJ
FORC37_RS03735	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FORC37_RS03740	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FORC37_RS03750	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FORC37_RS03755	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FORC37_RS03760	COG2190	(PTS) system
FORC37_RS03765	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FORC37_RS03770	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC37_RS03775	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FORC37_RS03780	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
FORC37_RS03810	COG0330	HflC and HflK could
FORC37_RS03815	COG3118	belongs to the thioredoxin family
FORC37_RS03820	COG0300	oxidoreductase activity
FORC37_RS03825	COG1090	epimerase
FORC37_RS03850	COG0622	Phosphoesterase
FORC37_RS03870	COG3710	Transcriptional regulator
FORC37_RS03875	COG0326	Molecular chaperone. Has ATPase activity
FORC37_RS03885	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FORC37_RS03895	COG3104	oligopeptide transport
FORC37_RS03905	COG0367	asparagine synthase
FORC37_RS03910	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FORC37_RS03910	COG4651	solute:proton antiporter activity
FORC37_RS03915	COG1846	Transcriptional regulator
FORC37_RS03915	COG1940	carbohydrate kinase activity
FORC37_RS03920	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FORC37_RS03925	COG2190	(PTS) system
FORC37_RS03925	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC37_RS03925	COG1263	PTS System
FORC37_RS03930	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FORC37_RS03945	COG0716	FMN binding
FORC37_RS03955	COG0596	Alpha beta hydrolase
FORC37_RS03960	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
FORC37_RS03965	COG0033	Phosphoglucomutase
FORC37_RS03970	COG2964	Protein conserved in bacteria
FORC37_RS03975	COG0251	oxidation-reduction process
FORC37_RS03985	COG0446	pyridine nucleotide-disulphide oxidoreductase
FORC37_RS03995	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FORC37_RS04005	COG2009	succinate dehydrogenase
FORC37_RS04010	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FORC37_RS04015	COG1053	succinate dehydrogenase
FORC37_RS04025	COG0567	Dehydrogenase, E1 component
FORC37_RS04030	COG0508	dehydrogenase complex catalyzes the overall conversion of
FORC37_RS04045	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FORC37_RS04050	COG1121	(ABC) transporter
FORC37_RS04055	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
FORC37_RS04065	COG1918	ferrous iron import across plasma membrane
FORC37_RS04070	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FORC37_RS04090	COG3102	Protein conserved in bacteria
FORC37_RS04095	COG0788	formyltetrahydrofolate deformylase activity
FORC37_RS04105	COG1199	ATP-dependent helicase activity
FORC37_RS04110	COG1214	PFAM Peptidase M22, glycoprotease
FORC37_RS04125	COG0596	Alpha beta hydrolase
FORC37_RS04130	COG0318	PFAM AMP-dependent synthetase and ligase
FORC37_RS04135	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FORC37_RS04140	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FORC37_RS04145	COG2894	cell division
FORC37_RS04150	COG0850	regulation of cytokinetic process
FORC37_RS04160	COG2951	lytic endotransglycosylase activity
FORC37_RS04170	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FORC37_RS04180	COG0745	RESPONSE REGULATOR receiver
FORC37_RS04185	COG5002	protein histidine kinase activity
FORC37_RS04200	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FORC37_RS04385	COG3561	AntA/AntB antirepressor
FORC37_RS04445	COG1695	Transcriptional regulator
FORC37_RS04465	COG1028	Short-chain dehydrogenase reductase Sdr
FORC37_RS04475	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FORC37_RS04500	COG2986	histidine ammonia-lyase
FORC37_RS04505	COG1216	Glycosyl transferase, family 2
FORC37_RS04525	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FORC37_RS04530	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FORC37_RS04595	COG1175	transmembrane transport
FORC37_RS04605	COG3842	ATPase activity
FORC37_RS04610	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FORC37_RS04615	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FORC37_RS04620	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FORC37_RS04630	COG2204	response regulator
FORC37_RS04635	COG4191	Histidine kinase
FORC37_RS04640	COG0544	peptidyl-prolyl cis-trans isomerase activity
FORC37_RS04650	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FORC37_RS04655	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FORC37_RS04660	COG0776	regulation of translation
FORC37_RS04665	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FORC37_RS04670	COG1555	photosystem II stabilization
FORC37_RS04680	COG3148	PFAM DTW domain containing protein
FORC37_RS04685	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FORC37_RS04690	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
FORC37_RS04695	COG0436	Aminotransferase
FORC37_RS04700	COG1169	isochorismate synthase
FORC37_RS04715	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FORC37_RS04785	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FORC37_RS04800	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FORC37_RS04805	COG1522	sequence-specific DNA binding
FORC37_RS04815	COG1946	Acyl-CoA thioesterase
FORC37_RS04820	COG3126	Type III secretion system lipoprotein chaperone (YscW)
FORC37_RS04870	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FORC37_RS04885	COG3139	Protein of unknown function (DUF1315)
FORC37_RS04890	COG0252	asparaginase activity
FORC37_RS04895	COG0616	signal peptide processing
FORC37_RS04900	COG1902	pentaerythritol trinitrate reductase activity
FORC37_RS04900	COG0446	pyridine nucleotide-disulphide oxidoreductase
FORC37_RS04905	COG0778	Nitroreductase
FORC37_RS04910	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FORC37_RS04915	COG0123	including yeast histone deacetylase and acetoin utilization protein
FORC37_RS04920	COG0784	Response regulator, receiver
FORC37_RS04920	COG2205	protein histidine kinase activity
FORC37_RS04930	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FORC37_RS04935	COG2731	YhcH YjgK YiaL family protein
FORC37_RS04940	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FORC37_RS04945	COG0569	domain protein
FORC37_RS04975	COG3083	sulfuric ester hydrolase activity
FORC37_RS04980	COG3082	Protein of unknown function (DUF1414)
FORC37_RS04985	COG3081	Nucleoid-associated protein
FORC37_RS05000	COG1757	Na H antiporter
FORC37_RS05005	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FORC37_RS05015	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FORC37_RS05020	COG2095	MarC family integral membrane protein
FORC37_RS05025	COG1012	belongs to the aldehyde dehydrogenase family
FORC37_RS05025	COG1454	alcohol dehydrogenase
FORC37_RS05030	COG1028	Short-chain dehydrogenase reductase Sdr
FORC37_RS05045	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FORC37_RS05055	COG2056	Na+-H+ antiporter family
FORC37_RS05060	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FORC37_RS05065	COG2885	chlorophyll binding
FORC37_RS05075	COG0346	lactoylglutathione lyase activity
FORC37_RS05080	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FORC37_RS05085	COG4660	Part of a membrane complex involved in electron transport
FORC37_RS05090	COG4659	FMN binding
FORC37_RS05095	COG4658	electron transport chain
FORC37_RS05100	COG4656	Part of a membrane complex involved in electron transport
FORC37_RS05105	COG2878	Part of a membrane complex involved in electron transport
FORC37_RS05110	COG4657	Part of a membrane complex involved in electron transport
FORC37_RS05125	COG0556	nucleotide-excision repair
FORC37_RS05130	COG2204	response regulator
FORC37_RS05135	COG2198	Histidine kinase
FORC37_RS05140	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FORC37_RS05150	COG0521	Mo-molybdopterin cofactor biosynthetic process
FORC37_RS05155	COG0315	cyclic pyranopterin monophosphate synthase activity
FORC37_RS05160	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FORC37_RS05165	COG0314	molybdopterin synthase activity
FORC37_RS05175	COG0601	transmembrane transport
FORC37_RS05180	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FORC37_RS05185	COG0444	Belongs to the ABC transporter superfamily
FORC37_RS05195	COG0435	Glutathione S-transferase
FORC37_RS05205	COG2350	Protein conserved in bacteria
FORC37_RS05225	COG1301	dicarboxylic acid transport
FORC37_RS05235	COG0133	tryptophan synthase activity
FORC37_RS05240	COG0135	phosphoribosylanthranilate isomerase activity
FORC37_RS05240	COG0134	indole-3-glycerol-phosphate synthase activity
FORC37_RS05245	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FORC37_RS05250	COG0512	Glutamine amidotransferase of anthranilate synthase
FORC37_RS05255	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FORC37_RS05265	COG0613	PHP domain protein
FORC37_RS05270	COG0009	L-threonylcarbamoyladenylate synthase
FORC37_RS05290	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FORC37_RS05300	COG5001	Diguanylate cyclase
FORC37_RS05305	COG0417	DNA replication proofreading
FORC37_RS05310	COG2197	response regulator
FORC37_RS05315	COG0322	excinuclease ABC activity
FORC37_RS05385	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FORC37_RS05390	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FORC37_RS05395	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FORC37_RS05420	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
FORC37_RS05425	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
FORC37_RS05430	COG0437	4 iron, 4 sulfur cluster binding
FORC37_RS05435	COG3301	Polysulphide reductase, NrfD
FORC37_RS05440	COG1138	Cytochrome C-type biogenesis protein
FORC37_RS05450	COG3088	subunit of a heme lyase
FORC37_RS05465	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FORC37_RS05465	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FORC37_RS05470	COG0489	protein tyrosine kinase activity
FORC37_RS05475	COG0572	uridine kinase
FORC37_RS05485	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
FORC37_RS05490	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FORC37_RS05495	COG0659	secondary active sulfate transmembrane transporter activity
FORC37_RS05500	COG1530	ribonuclease E activity
FORC37_RS05510	COG0424	maF-like protein
FORC37_RS05515	COG1399	metal-binding, possibly nucleic acid-binding protein
FORC37_RS05520	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FORC37_RS05525	COG0416	fatty acid biosynthetic process
FORC37_RS05530	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FORC37_RS05545	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FORC37_RS05560	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FORC37_RS05565	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FORC37_RS05575	COG0084	hydrolase, TatD family'
FORC37_RS05580	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC37_RS05580	COG1263	PTS System
FORC37_RS05595	COG0733	neurotransmitter:sodium symporter activity
FORC37_RS05605	COG4667	esterase of the alpha-beta hydrolase superfamily
FORC37_RS05610	COG0469	pyruvate kinase activity
FORC37_RS05615	COG1940	carbohydrate kinase activity
FORC37_RS05620	COG0784	Response regulator, receiver
FORC37_RS05620	COG0835	chemotaxis
FORC37_RS05625	COG0587	DNA-directed DNA polymerase activity
FORC37_RS05640	COG1028	Short-chain dehydrogenase reductase Sdr
FORC37_RS05645	COG0616	signal peptide processing
FORC37_RS05655	COG0539	negative regulation of cytoplasmic translation
FORC37_RS05665	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
FORC37_RS05670	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
FORC37_RS05675	COG0284	orotidine-5'-phosphate decarboxylase activity
FORC37_RS05680	COG4174	ABC transporter (Permease)
FORC37_RS05685	COG4239	(ABC) transporter, permease
FORC37_RS05690	COG4166	transmembrane transport
FORC37_RS05695	COG0444	Belongs to the ABC transporter superfamily
FORC37_RS05700	COG4608	Belongs to the ABC transporter superfamily
FORC37_RS05725	COG0583	DNA-binding transcription factor activity
FORC37_RS05735	COG0686	Belongs to the AlaDH PNT family
FORC37_RS05750	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FORC37_RS05755	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FORC37_RS05770	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FORC37_RS05785	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FORC37_RS05795	COG0501	Belongs to the peptidase M48B family
FORC37_RS05805	COG1028	Short-chain dehydrogenase reductase Sdr
FORC37_RS05820	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FORC37_RS05840	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FORC37_RS05845	COG2915	High frequency lysogenization protein hflD homolog
FORC37_RS05850	COG0482	sulfurtransferase activity
FORC37_RS05860	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FORC37_RS05865	COG2916	Histone family protein nucleoid-structuring protein H-NS
FORC37_RS05870	COG1757	Na H antiporter
FORC37_RS05875	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FORC37_RS05880	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FORC37_RS05885	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FORC37_RS05890	COG0131	Imidazoleglycerol-phosphate dehydratase
FORC37_RS05890	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FORC37_RS05895	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FORC37_RS05900	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FORC37_RS05915	COG3012	SEC-C Motif Domain Protein
FORC37_RS05920	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FORC37_RS05925	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FORC37_RS05930	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FORC37_RS05940	COG1435	thymidine kinase activity
FORC37_RS05950	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FORC37_RS05955	COG0583	DNA-binding transcription factor activity
FORC37_RS05975	COG2116	formate transmembrane transporter activity
FORC37_RS05980	COG0390	transport system, permease component
FORC37_RS05985	COG4459	periplasmic nitrate reductase
FORC37_RS05990	COG3005	denitrification pathway
FORC37_RS05995	COG0243	molybdopterin cofactor binding
FORC37_RS06025	COG1227	inorganic diphosphatase activity
FORC37_RS06040	COG4172	Belongs to the ABC transporter superfamily
FORC37_RS06065	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
FORC37_RS06070	COG1842	Phage shock protein A
FORC37_RS06080	COG1983	PspC domain protein
FORC37_RS06100	COG2818	Glycosylase
FORC37_RS06105	COG0626	cystathionine gamma-synthase activity
FORC37_RS06115	COG0733	neurotransmitter:sodium symporter activity
FORC37_RS06125	COG0564	pseudouridine synthase activity
FORC37_RS06135	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FORC37_RS06140	COG1151	hydroxylamine reductase activity
FORC37_RS06145	COG3604	Transcriptional regulator
FORC37_RS06150	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FORC37_RS06155	COG4136	ATPase activity
FORC37_RS06160	COG4135	transport system, permease component
FORC37_RS06165	COG4134	Bacterial extracellular solute-binding protein
FORC37_RS06175	COG3313	Fe-S protein
FORC37_RS06205	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FORC37_RS06210	COG2205	protein histidine kinase activity
FORC37_RS06225	COG1061	Type III restriction enzyme res subunit
FORC37_RS06235	COG2814	Major facilitator Superfamily
FORC37_RS06245	COG0702	epimerase
FORC37_RS06250	COG1136	(ABC) transporter
FORC37_RS06265	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FORC37_RS06280	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FORC37_RS06285	COG2985	domain, Protein
FORC37_RS06285	COG3273	potassium ion transport
FORC37_RS06290	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FORC37_RS06295	COG1979	alcohol dehydrogenase
FORC37_RS06300	COG1737	Transcriptional regulator
FORC37_RS06305	COG0076	glutamate decarboxylase activity
FORC37_RS06315	COG2431	L-lysine efflux transmembrane transporter activity
FORC37_RS06325	COG3070	regulator of competence-specific genes
FORC37_RS06340	COG5002	protein histidine kinase activity
FORC37_RS06340	COG5002	protein histidine kinase activity
FORC37_RS06355	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FORC37_RS06360	COG4988	ABC transporter
FORC37_RS06365	COG0492	ferredoxin-NADP+ reductase activity
FORC37_RS06375	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FORC37_RS06390	COG0471	metal ion transport
FORC37_RS06395	COG2949	membrane
FORC37_RS06400	COG0281	malic enzyme
FORC37_RS06405	COG1643	Atp-dependent helicase
FORC37_RS06420	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FORC37_RS06430	COG1346	cytolysis
FORC37_RS06435	COG1380	Effector of murein hydrolase LrgA
FORC37_RS06440	COG2925	Exonuclease
FORC37_RS06460	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FORC37_RS06490	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
FORC37_RS06525	COG1451	nucleotide metabolic process
FORC37_RS06540	COG3063	Type IV pilus biogenesis stability protein PilW
FORC37_RS06545	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FORC37_RS06550	COG0737	Belongs to the 5'-nucleotidase family
FORC37_RS06555	COG2195	Cleaves the N-terminal amino acid of tripeptides
FORC37_RS06565	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
FORC37_RS06575	COG0625	glutathione transferase activity
FORC37_RS06615	COG1278	Cold shock
FORC37_RS06625	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FORC37_RS06630	COG0584	glycerophosphoryl diester phosphodiesterase
FORC37_RS06635	COG1349	DNA-binding transcription factor activity
FORC37_RS06640	COG3842	ATPase activity
FORC37_RS06645	COG0395	ABC-type sugar transport system, permease component
FORC37_RS06650	COG1175	transmembrane transport
FORC37_RS06655	COG1653	transport
FORC37_RS06665	COG0840	transmembrane signaling receptor activity
FORC37_RS06670	COG0730	response to heat
FORC37_RS06680	COG2197	response regulator
FORC37_RS06725	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FORC37_RS06730	COG0372	Belongs to the citrate synthase family
FORC37_RS06735	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FORC37_RS06740	COG2828	Protein conserved in bacteria
FORC37_RS06780	COG0561	phosphatase activity
FORC37_RS06785	COG0602	queuosine metabolic process
FORC37_RS06790	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FORC37_RS06795	COG3706	GGDEF domain
FORC37_RS06820	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FORC37_RS06830	COG1254	Belongs to the acylphosphatase family
FORC37_RS06835	COG2920	part of a sulfur-relay system
FORC37_RS06840	COG0670	Belongs to the BI1 family
FORC37_RS06845	COG1126	abc transporter atp-binding protein
FORC37_RS06850	COG0765	amino acid transport
FORC37_RS06855	COG4597	amino acid ABC transporter
FORC37_RS06860	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC37_RS06870	COG0437	4 iron, 4 sulfur cluster binding
FORC37_RS06875	COG0348	domain, Protein
FORC37_RS06880	COG0204	Acyl-transferase
FORC37_RS06885	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
FORC37_RS06900	COG1115	amino acid carrier protein
FORC37_RS06930	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FORC37_RS06945	COG3290	protein histidine kinase activity
FORC37_RS06950	COG4565	transcriptional regulatory protein
FORC37_RS06955	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FORC37_RS06960	COG0363	glucosamine-6-phosphate deaminase activity
FORC37_RS06965	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FORC37_RS07000	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FORC37_RS07010	COG0438	transferase activity, transferring glycosyl groups
FORC37_RS07055	COG2204	response regulator
FORC37_RS07085	COG1366	Belongs to the anti-sigma-factor antagonist family
FORC37_RS07090	COG1793	dna ligase
FORC37_RS07095	COG3706	GGDEF domain
FORC37_RS07105	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FORC37_RS07120	COG2996	Protein conserved in bacteria
FORC37_RS07125	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
FORC37_RS07125	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FORC37_RS07130	COG3008	intermembrane lipid transfer
FORC37_RS07135	COG2995	paraquat-inducible protein a
FORC37_RS07140	COG1132	(ABC) transporter
FORC37_RS07145	COG1956	GAF domain-containing protein
FORC37_RS07150	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
FORC37_RS07165	COG0308	aminopeptidase N
FORC37_RS07175	COG2902	Dehydrogenase
FORC37_RS07190	COG0116	Belongs to the methyltransferase superfamily
FORC37_RS07190	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FORC37_RS07200	COG0488	(ABC) transporter
FORC37_RS07215	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FORC37_RS07220	COG1067	ATP-dependent peptidase activity
FORC37_RS07225	COG3120	sequence-specific DNA binding
FORC37_RS07245	COG0784	Response regulator, receiver
FORC37_RS07245	COG2205	protein histidine kinase activity
FORC37_RS07260	COG3278	Belongs to the heme-copper respiratory oxidase family
FORC37_RS07275	COG2010	Cytochrome c
FORC37_RS07285	COG2217	Heavy metal translocating P-type atpase
FORC37_RS07300	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FORC37_RS07305	COG0589	response to stress
FORC37_RS07320	COG2992	FlgJ-related protein
FORC37_RS07330	COG3842	ATPase activity
FORC37_RS07335	COG1176	ABC-type spermidine putrescine transport system, permease component I
FORC37_RS07340	COG1177	transmembrane transport
FORC37_RS07350	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FORC37_RS07355	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FORC37_RS07360	COG0004	ammonium transporteR
FORC37_RS07390	COG0437	4 iron, 4 sulfur cluster binding
FORC37_RS07395	COG0243	molybdopterin cofactor binding
FORC37_RS07395	COG3383	formate dehydrogenase (NAD+) activity
FORC37_RS07425	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FORC37_RS07435	COG0488	(ABC) transporter
FORC37_RS07450	COG3852	Histidine kinase
FORC37_RS07455	COG2204	response regulator
FORC37_RS07465	COG4662	Binding-protein-dependent transport system inner membrane component
FORC37_RS07470	COG3842	ATPase activity
FORC37_RS07475	COG0746	molybdenum cofactor guanylyltransferase activity
FORC37_RS07480	COG0303	'Molybdopterin
FORC37_RS07490	COG1940	carbohydrate kinase activity
FORC37_RS07495	COG3148	PFAM DTW domain containing protein
FORC37_RS07505	COG0840	transmembrane signaling receptor activity
FORC37_RS07510	COG0791	NLP P60 protein
FORC37_RS07520	COG3706	GGDEF domain
FORC37_RS07540	COG0307	riboflavin synthase, alpha
FORC37_RS07545	COG0534	Mate efflux family protein
FORC37_RS07685	COG4628	conserved protein (DUF2132)
FORC37_RS07865	COG0454	-acetyltransferase
FORC37_RS08040	COG0454	-acetyltransferase
FORC37_RS08615	COG1028	Short-chain dehydrogenase reductase Sdr
FORC37_RS08770	COG0346	lactoylglutathione lyase activity
FORC37_RS09060	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FORC37_RS09180	COG3772	lysozyme
FORC37_RS09255	COG0582	viral genome integration into host DNA
FORC37_RS09265	COG4326	sporulation control protein
FORC37_RS09275	COG1228	amidohydrolase
FORC37_RS09285	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FORC37_RS09290	COG2986	histidine ammonia-lyase
FORC37_RS09300	COG5640	endopeptidase activity
FORC37_RS09305	COG2020	methyltransferase activity
FORC37_RS09310	COG0277	FAD linked oxidase domain protein
FORC37_RS09310	COG0247	lactate metabolic process
FORC37_RS09325	COG2885	chlorophyll binding
FORC37_RS09340	COG0295	cytidine deaminase activity
FORC37_RS09345	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
FORC37_RS09350	COG0500	methyltransferase
FORC37_RS09360	COG0776	regulation of translation
FORC37_RS09380	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FORC37_RS09380	COG0072	phenylalanine-tRNA ligase activity
FORC37_RS09385	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FORC37_RS09450	COG1166	arginine decarboxylase activity
FORC37_RS09455	COG0010	Belongs to the arginase family
FORC37_RS09460	COG2814	Major facilitator Superfamily
FORC37_RS09465	COG5380	lipid catabolic process
FORC37_RS09470	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
FORC37_RS09495	COG1643	Atp-dependent helicase
FORC37_RS09505	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FORC37_RS09545	COG2894	cell division
FORC37_RS09555	COG4964	Belongs to the GSP D family
FORC37_RS09585	COG3713	MltA-interacting MipA family protein
FORC37_RS09605	COG3706	GGDEF domain
FORC37_RS09615	COG0443	Heat shock 70 kDa protein
FORC37_RS09620	COG0443	Heat shock 70 kDa protein
FORC37_RS09660	COG2165	general secretion pathway protein
FORC37_RS09675	COG0438	transferase activity, transferring glycosyl groups
FORC37_RS09675	COG0297	glycogen (starch) synthase activity
FORC37_RS09705	COG1596	polysaccharide export
FORC37_RS09715	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FORC37_RS09720	COG1115	amino acid carrier protein
FORC37_RS09725	COG1132	(ABC) transporter
FORC37_RS09730	COG1132	(ABC) transporter
FORC37_RS09745	COG0783	Belongs to the Dps family
FORC37_RS09760	COG0814	amino acid
FORC37_RS09765	COG1597	lipid kinase activity
FORC37_RS09775	COG4667	esterase of the alpha-beta hydrolase superfamily
FORC37_RS09785	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FORC37_RS09800	COG0583	DNA-binding transcription factor activity
FORC37_RS09805	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FORC37_RS09810	COG1328	CTP reductase activity
FORC37_RS09815	COG5001	Diguanylate cyclase
FORC37_RS09815	COG3300	MHYT domain
FORC37_RS09830	COG2200	EAL domain
FORC37_RS09830	COG2199	diguanylate cyclase activity
FORC37_RS09835	COG3706	GGDEF domain
FORC37_RS09845	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC37_RS09845	COG4191	Histidine kinase
FORC37_RS09850	COG0471	metal ion transport
FORC37_RS09865	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC37_RS09870	COG3283	Transcriptional regulator of aromatic amino acids metabolism
FORC37_RS09875	COG3768	UPF0283 membrane protein
FORC37_RS09880	COG3106	COG3106 Predicted ATPase
FORC37_RS09895	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FORC37_RS09900	COG0784	Response regulator, receiver
FORC37_RS09900	COG2205	protein histidine kinase activity
FORC37_RS09910	COG0494	nUDIX hydrolase
FORC37_RS09915	COG0814	amino acid
FORC37_RS09920	COG1760	l-serine dehydratase
FORC37_RS09925	COG2200	EAL domain
FORC37_RS09935	COG0720	synthase
FORC37_RS09945	COG0017	Asparaginyl-tRNA synthetase
FORC37_RS09960	COG2770	Histidine kinase
FORC37_RS09960	COG3437	response regulator, receiver
FORC37_RS09965	COG1448	Aminotransferase
FORC37_RS09985	COG0840	transmembrane signaling receptor activity
FORC37_RS09990	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FORC37_RS09995	COG1846	Transcriptional regulator
FORC37_RS10020	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FORC37_RS10040	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FORC37_RS10045	COG3108	Peptidase M15
FORC37_RS10050	COG2989	Protein conserved in bacteria
FORC37_RS10080	COG2186	Transcriptional regulator
FORC37_RS10085	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FORC37_RS10095	COG0653	protein targeting
FORC37_RS10110	COG0366	Alpha amylase catalytic
FORC37_RS10120	COG4120	Belongs to the binding-protein-dependent transport system permease family
FORC37_RS10130	COG3092	negative regulation of chromosome organization
FORC37_RS10135	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FORC37_RS10140	COG0857	belongs to the CobB CobQ family
FORC37_RS10140	COG0280	phosphate acetyltransferase
FORC37_RS10145	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FORC37_RS10150	COG0583	DNA-binding transcription factor activity
FORC37_RS10175	COG1032	radical SAM domain protein
FORC37_RS10195	COG2207	Transcriptional regulator
FORC37_RS10215	COG0861	Integral membrane protein TerC family
FORC37_RS10220	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FORC37_RS10225	COG0840	transmembrane signaling receptor activity
FORC37_RS10235	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FORC37_RS10250	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FORC37_RS10315	COG0784	Response regulator, receiver
FORC37_RS10315	COG2205	protein histidine kinase activity
FORC37_RS10325	COG0754	glutathionylspermidine amidase activity
FORC37_RS10335	COG3766	membrane
FORC37_RS10345	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FORC37_RS10350	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
FORC37_RS10355	COG2885	chlorophyll binding
FORC37_RS10360	COG0823	Involved in the tonB-independent uptake of proteins
FORC37_RS10375	COG0811	peptide transport
FORC37_RS10380	COG0824	Thioesterase
FORC37_RS10390	COG4890	Cyd operon protein YbgT
FORC37_RS10395	COG1294	oxidase, subunit
FORC37_RS10400	COG1271	oxidase subunit
FORC37_RS10405	COG2255	four-way junction helicase activity
FORC37_RS10410	COG0632	four-way junction helicase activity
FORC37_RS10430	COG4106	trans-aconitate 2-methyltransferase activity
FORC37_RS10435	COG0500	methyltransferase
FORC37_RS10440	COG4067	protein conserved in archaea
FORC37_RS10440	COG0189	ligase activity
FORC37_RS10470	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FORC37_RS10475	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
FORC37_RS10480	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
FORC37_RS10485	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FORC37_RS10490	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FORC37_RS10495	COG0745	RESPONSE REGULATOR receiver
FORC37_RS10505	COG1609	Transcriptional regulator
FORC37_RS10510	COG3070	regulator of competence-specific genes
FORC37_RS10535	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FORC37_RS10545	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FORC37_RS10555	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FORC37_RS10570	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FORC37_RS10575	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FORC37_RS10580	COG0542	response to heat
FORC37_RS10585	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FORC37_RS10590	COG1278	Cold shock
FORC37_RS10610	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FORC37_RS10615	COG1199	ATP-dependent helicase activity
FORC37_RS10625	COG3923	Primosomal replication protein n
FORC37_RS10635	COG0840	transmembrane signaling receptor activity
FORC37_RS10640	COG0708	Exodeoxyribonuclease III
FORC37_RS10680	COG1882	Formate acetyltransferase
FORC37_RS10695	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FORC37_RS10705	COG3013	Belongs to the UPF0304 family
FORC37_RS10710	COG2766	serine protein kinase
FORC37_RS10715	COG2718	Belongs to the UPF0229 family
FORC37_RS10720	COG2719	SpoVR family
FORC37_RS10725	COG2199	diguanylate cyclase activity
FORC37_RS10730	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FORC37_RS10735	COG2835	tetraacyldisaccharide 4'-kinase activity
FORC37_RS10740	COG1663	tetraacyldisaccharide 4'-kinase activity
FORC37_RS10750	COG0658	competence protein
FORC37_RS10750	COG2333	competence protein COMEC
FORC37_RS10760	COG4591	ABC-type transport system involved in lipoprotein release permease component
FORC37_RS10765	COG1136	(ABC) transporter
FORC37_RS10770	COG4591	ABC-type transport system involved in lipoprotein release permease component
FORC37_RS10780	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FORC37_RS10795	COG1252	NADH dehydrogenase
FORC37_RS10825	COG0537	adenosine 5'-monophosphoramidase activity
FORC37_RS10850	COG0617	tRNA 3'-terminal CCA addition
FORC37_RS10850	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FORC37_RS10850	COG0517	IMP dehydrogenase activity
FORC37_RS10855	COG3706	GGDEF domain
FORC37_RS10860	COG1982	Orn Lys Arg decarboxylase major
FORC37_RS10865	COG0531	amino acid
FORC37_RS10870	COG3710	Transcriptional regulator
FORC37_RS10885	COG2199	diguanylate cyclase activity
FORC37_RS10885	COG2203	Gaf domain
FORC37_RS10890	COG2239	Acts as a magnesium transporter
FORC37_RS10900	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FORC37_RS10905	COG2226	methyltransferase
FORC37_RS10920	COG1785	Belongs to the alkaline phosphatase family
FORC37_RS10930	COG0346	lactoylglutathione lyase activity
FORC37_RS10940	COG2983	Belongs to the UPF0260 family
FORC37_RS10955	COG0745	RESPONSE REGULATOR receiver
FORC37_RS10960	COG2205	protein histidine kinase activity
FORC37_RS10975	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FORC37_RS10980	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FORC37_RS10990	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FORC37_RS10995	COG2832	Protein of unknown function (DUF454)
FORC37_RS11005	COG0745	RESPONSE REGULATOR receiver
FORC37_RS11010	COG0583	DNA-binding transcription factor activity
FORC37_RS11015	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FORC37_RS11020	COG1286	toxin biosynthetic process
FORC37_RS11025	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
FORC37_RS11030	COG0285	dihydrofolate synthase activity
FORC37_RS11035	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FORC37_RS11040	COG0101	tRNA pseudouridine synthase activity
FORC37_RS11050	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FORC37_RS11060	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FORC37_RS11075	COG3101	peptidyl-lysine hydroxylation
FORC37_RS11080	COG2860	membrane
FORC37_RS11090	COG2890	protein-(glutamine-N5) methyltransferase activity
FORC37_RS11095	COG2840	Smr protein MutS2
FORC37_RS11100	COG2062	phosphohistidine phosphatase, SixA
FORC37_RS11110	COG1025	Belongs to the peptidase M16 family
FORC37_RS11135	COG2067	long-chain fatty acid transport protein
FORC37_RS11140	COG2067	long-chain fatty acid transport protein
FORC37_RS11145	COG2853	Lipoprotein
FORC37_RS11155	COG3088	subunit of a heme lyase
FORC37_RS11155	COG4235	cytochrome complex assembly
FORC37_RS11160	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FORC37_RS11165	COG1138	Cytochrome C-type biogenesis protein
FORC37_RS11170	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
FORC37_RS11175	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FORC37_RS11180	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FORC37_RS11185	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FORC37_RS11190	COG4133	protoheme IX ABC transporter activity
FORC37_RS11200	COG0835	chemotaxis
FORC37_RS11210	COG1192	Involved in chromosome partitioning
FORC37_RS11220	COG2198	Histidine kinase
FORC37_RS11220	COG0784	Response regulator, receiver
FORC37_RS11220	COG0643	Histidine kinase
FORC37_RS11225	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
FORC37_RS11260	COG1684	flagellar biosynthetic protein fliR
FORC37_RS11265	COG1987	bacterial-type flagellum assembly
FORC37_RS11315	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FORC37_RS11325	COG1677	Flagellar hook-basal body complex protein FliE
FORC37_RS11345	COG1516	flagellar protein fliS
FORC37_RS11355	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FORC37_RS11360	COG1334	flagellar protein FlaG
FORC37_RS11365	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FORC37_RS11370	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FORC37_RS11375	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FORC37_RS11380	COG2837	iron assimilation
FORC37_RS11405	COG1393	Belongs to the ArsC family
FORC37_RS11425	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
FORC37_RS11430	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FORC37_RS11435	COG2716	regulation of RNA biosynthetic process
FORC37_RS11440	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FORC37_RS11455	COG4783	chaperone-mediated protein folding
FORC37_RS11460	COG1393	Belongs to the ArsC family
FORC37_RS11480	COG2233	PERMEase
FORC37_RS11485	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FORC37_RS11490	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FORC37_RS11495	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FORC37_RS11500	COG0121	glutamine amidotransferase
FORC37_RS11510	COG1960	acyl-CoA dehydrogenase activity
FORC37_RS11540	COG2249	NAD(P)H dehydrogenase (quinone) activity
FORC37_RS11555	COG0328	RNA-DNA hybrid ribonuclease activity
FORC37_RS11560	COG2226	methyltransferase
FORC37_RS11565	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FORC37_RS11570	COG1388	LysM domain
FORC37_RS11570	COG0741	lytic transglycosylase activity
FORC37_RS11580	COG3021	interspecies interaction between organisms
FORC37_RS11585	COG0347	Belongs to the P(II) protein family
FORC37_RS11600	COG0825	malonyl-CoA metabolic process
FORC37_RS11605	COG0587	DNA-directed DNA polymerase activity
FORC37_RS11610	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FORC37_RS11615	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FORC37_RS11620	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FORC37_RS11625	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FORC37_RS11635	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
FORC37_RS11640	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FORC37_RS11645	COG0750	zinc metalloprotease
FORC37_RS11655	COG0575	Belongs to the CDS family
FORC37_RS11660	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FORC37_RS11665	COG0233	cytoplasmic translational termination
FORC37_RS11670	COG0528	UMP kinase activity
FORC37_RS11675	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FORC37_RS11680	COG0052	Belongs to the universal ribosomal protein uS2 family
FORC37_RS11685	COG0024	Methionine aminopeptidase
FORC37_RS11690	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FORC37_RS11705	COG3098	single-species biofilm formation
FORC37_RS11735	COG1671	Belongs to the UPF0178 family
FORC37_RS11740	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
FORC37_RS11750	COG0254	rRNA binding
FORC37_RS11755	COG1720	tRNA m6t6A37 methyltransferase activity
FORC37_RS11780	COG0733	neurotransmitter:sodium symporter activity
FORC37_RS11795	COG0514	ATP-dependent DNA helicase (RecQ)
FORC37_RS11800	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FORC37_RS11815	COG1477	protein flavinylation
FORC37_RS11820	COG2871	sodium ion transport
FORC37_RS11825	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FORC37_RS11835	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FORC37_RS11840	COG1805	sodium ion transport
FORC37_RS11845	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FORC37_RS11850	COG0271	Belongs to the BolA IbaG family
FORC37_RS11855	COG2813	Specifically methylates the guanine in position
FORC37_RS11865	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FORC37_RS11870	COG2211	Major facilitator Superfamily
FORC37_RS11880	COG1595	DNA-templated transcription, initiation
FORC37_RS11890	COG3248	Nucleoside-binding outer membrane protein
FORC37_RS11895	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FORC37_RS11900	COG0693	protein deglycase activity
FORC37_RS11905	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FORC37_RS11915	COG2166	iron-sulfur cluster assembly
FORC37_RS11920	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FORC37_RS11925	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FORC37_RS11945	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FORC37_RS11950	COG1074	ATP-dependent DNA helicase activity
FORC37_RS11955	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FORC37_RS11960	COG3083	sulfuric ester hydrolase activity
FORC37_RS11975	COG3141	response to X-ray
FORC37_RS11985	COG2171	N-acyltransferase activity
FORC37_RS11990	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FORC37_RS11995	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FORC37_RS12000	COG1349	DNA-binding transcription factor activity
FORC37_RS12005	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FORC37_RS12020	COG0189	ligase activity
FORC37_RS12020	COG0569	domain protein
FORC37_RS12035	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FORC37_RS12045	COG0840	transmembrane signaling receptor activity
FORC37_RS12050	COG2211	Major facilitator Superfamily
FORC37_RS12065	COG2017	converts alpha-aldose to the beta-anomer
FORC37_RS12075	COG1085	galactose-1-phosphate uridylyltransferase
FORC37_RS12080	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FORC37_RS12085	COG1609	Transcriptional regulator
FORC37_RS12095	COG3250	beta-galactosidase activity
FORC37_RS12100	COG2731	YhcH YjgK YiaL family protein
FORC37_RS12105	COG0531	amino acid
FORC37_RS12110	COG0531	amino acid
FORC37_RS12115	COG3408	Glycogen debranching enzyme
FORC37_RS12115	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
FORC37_RS12125	COG0583	DNA-binding transcription factor activity
FORC37_RS12130	COG2059	Chromate
FORC37_RS12180	COG4964	Belongs to the GSP D family
FORC37_RS12215	COG1022	Amp-dependent synthetase and ligase
FORC37_RS12220	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FORC37_RS12240	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FORC37_RS12250	COG0560	Phosphoserine phosphatase
FORC37_RS12260	COG0813	purine-nucleoside phosphorylase activity
FORC37_RS12265	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FORC37_RS12270	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FORC37_RS12275	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FORC37_RS12280	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FORC37_RS12285	COG0084	hydrolase, TatD family'
FORC37_RS12295	COG3706	GGDEF domain
FORC37_RS12305	COG0456	acetyltransferase
FORC37_RS12315	COG3153	acetyltransferase
FORC37_RS12320	COG3154	lipid carrier protein
FORC37_RS12330	COG0826	peptidase U32
FORC37_RS12335	COG0826	peptidase U32
FORC37_RS12340	COG0534	Mate efflux family protein
FORC37_RS12355	COG1185	polyribonucleotide nucleotidyltransferase activity
FORC37_RS12380	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FORC37_RS12385	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FORC37_RS12390	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FORC37_RS12400	COG0195	Participates in both transcription termination and antitermination
FORC37_RS12405	COG0779	Required for maturation of 30S ribosomal subunits
FORC37_RS12420	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FORC37_RS12425	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FORC37_RS12430	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FORC37_RS12435	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FORC37_RS12440	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FORC37_RS12445	COG1534	Rna-binding protein
FORC37_RS12465	COG2027	D-alanyl-D-alanine carboxypeptidase
FORC37_RS12470	COG2832	Protein of unknown function (DUF454)
FORC37_RS12475	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FORC37_RS12480	COG0739	heme binding
FORC37_RS12505	COG0628	permease
FORC37_RS12515	COG2205	protein histidine kinase activity
FORC37_RS12515	COG0784	Response regulator, receiver
FORC37_RS12520	COG0747	negative chemotaxis
FORC37_RS12525	COG0601	transmembrane transport
FORC37_RS12530	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FORC37_RS12535	COG0444	Belongs to the ABC transporter superfamily
FORC37_RS12540	COG4608	Belongs to the ABC transporter superfamily
FORC37_RS12550	COG2971	BadF BadG BcrA BcrD
FORC37_RS12565	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FORC37_RS12570	COG3842	ATPase activity
FORC37_RS12580	COG1840	ABC-type Fe3 transport system, periplasmic component
FORC37_RS12585	COG0004	ammonium transporteR
FORC37_RS12590	COG0347	Belongs to the P(II) protein family
FORC37_RS12595	COG3112	Uncharacterised protein family (UPF0231)
FORC37_RS12600	COG3835	regulator
FORC37_RS12605	COG2610	gluconate transmembrane transporter activity
FORC37_RS12610	COG1929	Belongs to the glycerate kinase type-1 family
FORC37_RS12615	COG1049	propionate catabolic process, 2-methylcitrate cycle
FORC37_RS12620	COG1752	Esterase of the alpha-beta hydrolase superfamily
FORC37_RS12625	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FORC37_RS12630	COG1643	Atp-dependent helicase
FORC37_RS12635	COG1489	DNA binding
FORC37_RS12640	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FORC37_RS12645	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FORC37_RS12655	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FORC37_RS12660	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FORC37_RS12670	COG0842	Transport permease protein
FORC37_RS12675	COG1131	(ABC) transporter
FORC37_RS12680	COG0659	secondary active sulfate transmembrane transporter activity
FORC37_RS12685	COG0288	reversible hydration of carbon dioxide
FORC37_RS12700	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FORC37_RS12705	COG0508	dehydrogenase complex catalyzes the overall conversion of
FORC37_RS12710	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FORC37_RS12715	COG2186	Transcriptional regulator
FORC37_RS12720	COG3023	N-Acetylmuramoyl-L-alanine amidase
FORC37_RS12735	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FORC37_RS12740	COG1459	type II secretion system
FORC37_RS12750	COG0237	dephospho-CoA kinase activity
FORC37_RS12760	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FORC37_RS12765	COG0335	large ribosomal subunit rRNA binding
FORC37_RS12770	COG0336	Belongs to the RNA methyltransferase TrmD family
FORC37_RS12775	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FORC37_RS12780	COG0228	four-way junction DNA binding
FORC37_RS12785	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FORC37_RS12790	COG4137	Cytochrome C assembly protein
FORC37_RS12795	COG4536	flavin adenine dinucleotide binding
FORC37_RS12800	COG1854	S-ribosylhomocysteine lyase activity
FORC37_RS12815	COG0612	Peptidase, M16
FORC37_RS12820	COG1238	metal cluster binding
FORC37_RS12830	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
FORC37_RS12835	COG5016	pyruvate
FORC37_RS12835	COG0511	ligase activity, forming carbon-carbon bonds
FORC37_RS12840	COG3630	sodium ion export across plasma membrane
FORC37_RS12885	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
FORC37_RS12890	COG0527	aspartate kinase activity
FORC37_RS12895	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FORC37_RS12905	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FORC37_RS12915	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FORC37_RS12920	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FORC37_RS12925	COG1388	LysM domain
FORC37_RS12925	COG4942	peptidase
FORC37_RS12930	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FORC37_RS12940	COG0585	pseudouridine synthase activity
FORC37_RS12945	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FORC37_RS12955	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
FORC37_RS12965	COG3344	reverse transcriptase
FORC37_RS12975	COG0504	CTP synthase activity
FORC37_RS12980	COG3956	TIGRFAM MazG family protein
FORC37_RS12985	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FORC37_RS12990	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FORC37_RS12995	COG3437	response regulator, receiver
FORC37_RS12995	COG2205	protein histidine kinase activity
FORC37_RS12995	COG3850	Histidine kinase
FORC37_RS12995	COG4999	Histidine kinase
FORC37_RS13015	COG0736	holo-[acyl-carrier-protein] synthase activity
FORC37_RS13020	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FORC37_RS13025	COG1381	Involved in DNA repair and RecF pathway recombination
FORC37_RS13030	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FORC37_RS13045	COG0481	GTPase activity
FORC37_RS13050	COG3086	response to oxidative stress
FORC37_RS13065	COG1595	DNA-templated transcription, initiation
FORC37_RS13070	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FORC37_RS13085	COG0354	folic acid binding
FORC37_RS13100	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FORC37_RS13105	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FORC37_RS13110	COG3079	Belongs to the UPF0149 family
FORC37_RS13115	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
FORC37_RS13125	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FORC37_RS13135	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FORC37_RS13150	COG1279	arginine transmembrane transporter activity
FORC37_RS13155	COG0668	transmembrane transport
FORC37_RS13160	COG0191	fructose-bisphosphate aldolase activity
FORC37_RS13165	COG0126	phosphoglycerate kinase activity
FORC37_RS13170	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FORC37_RS13180	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FORC37_RS13185	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FORC37_RS13200	COG2356	endonuclease I
FORC37_RS13210	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FORC37_RS13220	COG1678	Uncharacterized ACR, COG1678
FORC37_RS13225	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FORC37_RS13240	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FORC37_RS13245	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FORC37_RS13250	COG0762	integral membrane protein
FORC37_RS13265	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FORC37_RS13270	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FORC37_RS13275	COG2066	Belongs to the glutaminase family
FORC37_RS13280	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FORC37_RS13290	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
FORC37_RS13295	COG0741	lytic transglycosylase activity
FORC37_RS13415	COG1609	Transcriptional regulator
FORC37_RS13420	COG3394	polysaccharide catabolic process
FORC37_RS13425	COG1486	melibiose metabolic process
FORC37_RS13430	COG1447	Phosphotransferase system cellobiose-specific component IIA
FORC37_RS13440	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FORC37_RS13445	COG0726	polysaccharide deacetylase
FORC37_RS13460	COG0795	lipopolysaccharide-transporting ATPase activity
FORC37_RS13465	COG0795	lipopolysaccharide-transporting ATPase activity
FORC37_RS13470	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FORC37_RS13475	COG2927	DNA polymerase III (CHI subunit)
FORC37_RS13480	COG0525	valine-tRNA ligase activity
FORC37_RS13490	COG4269	membrane
FORC37_RS13500	COG0456	acetyltransferase
FORC37_RS13535	COG0251	oxidation-reduction process
FORC37_RS13540	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FORC37_RS13550	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FORC37_RS13555	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FORC37_RS13560	COG0312	modulator of DNA gyrase
FORC37_RS13565	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FORC37_RS13570	COG3164	Protein of unknown function
FORC37_RS13580	COG0424	maF-like protein
FORC37_RS13585	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FORC37_RS13590	COG1792	Involved in formation and maintenance of cell shape
FORC37_RS13595	COG1077	Cell shape determining protein MreB Mrl
FORC37_RS13630	COG2165	general secretion pathway protein
FORC37_RS13640	COG1459	type II secretion system
FORC37_RS13645	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FORC37_RS13655	COG3409	Peptidoglycan-binding domain 1 protein
FORC37_RS13655	COG3267	Type II secretory pathway component ExeA
FORC37_RS13680	COG2199	diguanylate cyclase activity
FORC37_RS13680	COG2200	EAL domain
FORC37_RS13700	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FORC37_RS13710	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FORC37_RS13715	COG0527	aspartate kinase activity
FORC37_RS13720	COG1410	methionine synthase
FORC37_RS13720	COG0646	methionine synthase
FORC37_RS13730	COG3706	GGDEF domain
FORC37_RS13815	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FORC37_RS13845	COG0735	belongs to the Fur family
FORC37_RS13860	COG0432	Pfam Uncharacterised protein family UPF0047
FORC37_RS13870	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FORC37_RS13885	COG0359	binds to the 23S rRNA
FORC37_RS13895	COG2965	DNA replication, synthesis of RNA primer
FORC37_RS13900	COG0360	Binds together with S18 to 16S ribosomal RNA
FORC37_RS13905	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FORC37_RS13910	COG0338	D12 class N6 adenine-specific DNA methyltransferase
FORC37_RS13920	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FORC37_RS13925	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FORC37_RS13955	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FORC37_RS13970	COG0165	Argininosuccinate lyase
FORC37_RS13970	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FORC37_RS13975	COG0137	argininosuccinate synthase activity
FORC37_RS13985	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FORC37_RS13990	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FORC37_RS13995	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FORC37_RS14005	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FORC37_RS14010	COG0460	homoserine dehydrogenase
FORC37_RS14010	COG0527	aspartate kinase activity
FORC37_RS14015	COG0626	cystathionine gamma-synthase activity
FORC37_RS14020	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
FORC37_RS14025	COG0281	malic enzyme
FORC37_RS14035	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FORC37_RS14040	COG1609	Transcriptional regulator
FORC37_RS14050	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FORC37_RS14055	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FORC37_RS14060	COG1575	Belongs to the MenA family. Type 1 subfamily
FORC37_RS14070	COG3074	FtsZ-dependent cytokinesis
FORC37_RS14080	COG1494	fructose-1,6-bisphosphatase
FORC37_RS14105	COG0149	triose-phosphate isomerase activity
FORC37_RS14110	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FORC37_RS14120	COG2906	2 iron, 2 sulfur cluster binding
FORC37_RS14130	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FORC37_RS14135	COG0049	tRNA binding
FORC37_RS14140	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FORC37_RS14155	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
FORC37_RS14160	COG2964	Protein conserved in bacteria
FORC37_RS14165	COG0545	Peptidyl-prolyl cis-trans isomerase
FORC37_RS14175	COG2900	Belongs to the SlyX family
FORC37_RS14185	COG1047	Peptidyl-prolyl cis-trans
FORC37_RS14200	COG2249	NAD(P)H dehydrogenase (quinone) activity
FORC37_RS14205	COG0488	(ABC) transporter
FORC37_RS14215	COG0429	hydrolase of the alpha beta-hydrolase fold
FORC37_RS14220	COG3089	Belongs to the UPF0270 family
FORC37_RS14225	COG3954	Phosphoribulokinase
FORC37_RS14230	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FORC37_RS14240	COG1012	belongs to the aldehyde dehydrogenase family
FORC37_RS14250	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FORC37_RS14270	COG0180	Tryptophanyl-tRNA synthetase
FORC37_RS14275	COG0546	phosphoglycolate phosphatase activity
FORC37_RS14280	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FORC37_RS14285	COG0557	exoribonuclease II activity
FORC37_RS14290	COG0402	S-adenosylhomocysteine deaminase activity
FORC37_RS14295	COG1959	2 iron, 2 sulfur cluster binding
FORC37_RS14305	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
FORC37_RS14310	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FORC37_RS14315	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
FORC37_RS14320	COG0330	HflC and HflK could
FORC37_RS14325	COG0330	HflC and HflK could
FORC37_RS14330	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FORC37_RS14335	COG1923	regulation of RNA biosynthetic process
FORC37_RS14345	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FORC37_RS14350	COG0860	N-Acetylmuramoyl-L-alanine amidase
FORC37_RS14355	COG0802	atpase or kinase
FORC37_RS14360	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FORC37_RS14420	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FORC37_RS14425	COG1162	GTPase activity
FORC37_RS14430	COG0688	phosphatidylethanolamine metabolic process
FORC37_RS14435	COG0471	metal ion transport
FORC37_RS14445	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FORC37_RS14455	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FORC37_RS14460	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FORC37_RS14465	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FORC37_RS14470	COG1045	serine acetyltransferase
FORC37_RS14475	COG4942	peptidase
FORC37_RS14495	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
FORC37_RS14500	COG1053	succinate dehydrogenase
FORC37_RS14505	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FORC37_RS14510	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
FORC37_RS14515	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
FORC37_RS14530	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FORC37_RS14535	COG1509	lysine 2,3-aminomutase activity
FORC37_RS14540	COG1285	pathogenesis
FORC37_RS14550	COG0459	protein refolding
FORC37_RS14555	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FORC37_RS14560	COG0534	Mate efflux family protein
FORC37_RS14565	COG0205	6-phosphofructokinase activity
FORC37_RS14575	COG3678	ATP-independent chaperone mediated protein folding
FORC37_RS14580	COG0745	RESPONSE REGULATOR receiver
FORC37_RS14585	COG2205	protein histidine kinase activity
FORC37_RS14590	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FORC37_RS14595	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FORC37_RS14605	COG1027	Aspartate ammonia-lyase
FORC37_RS14610	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FORC37_RS14615	COG4232	protein-disulfide reductase activity
FORC37_RS14625	COG2095	MarC family integral membrane protein
FORC37_RS14635	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FORC37_RS14650	COG2205	protein histidine kinase activity
FORC37_RS14650	COG0784	Response regulator, receiver
FORC37_RS14650	COG2198	Histidine kinase
FORC37_RS14655	COG2814	Major facilitator Superfamily
FORC37_RS14670	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FORC37_RS14675	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FORC37_RS14680	COG0511	ligase activity, forming carbon-carbon bonds
FORC37_RS14685	COG0439	Biotin carboxylase
FORC37_RS14690	COG2264	protein methyltransferase activity
FORC37_RS14700	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FORC37_RS14705	COG0840	transmembrane signaling receptor activity
FORC37_RS14710	COG0789	Transcriptional regulator
FORC37_RS14720	COG0138	bifunctional purine biosynthesis protein purh
FORC37_RS14740	COG1253	flavin adenine dinucleotide binding
FORC37_RS14745	COG3068	Protein conserved in bacteria
FORC37_RS14755	COG1573	uracil-dna glycosylase
FORC37_RS14760	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FORC37_RS14780	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
FORC37_RS14785	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FORC37_RS14790	COG0085	RNA polymerase activity
FORC37_RS14795	COG0222	ribosome binding
FORC37_RS14800	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FORC37_RS14805	COG0081	regulation of translation
FORC37_RS14820	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FORC37_RS14825	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FORC37_RS14860	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FORC37_RS14870	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FORC37_RS14955	COG4206	TonB-dependent receptor
FORC37_RS15015	COG3339	Conserved Protein
FORC37_RS15030	COG2003	Belongs to the UPF0758 family
FORC37_RS15080	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FORC37_RS15090	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FORC37_RS15100	COG2937	Belongs to the GPAT DAPAT family
FORC37_RS15110	COG3161	chorismate lyase activity
FORC37_RS15115	COG1580	Controls the rotational direction of flagella during chemotaxis
FORC37_RS15125	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FORC37_RS15135	COG2177	Part of the ABC transporter FtsEX involved in
FORC37_RS15140	COG2884	Cell division ATP-binding protein ftsE
FORC37_RS15145	COG0552	protein localization to endoplasmic reticulum
FORC37_RS15150	COG0742	ribosomal rna small subunit methyltransferase
FORC37_RS15160	COG2095	MarC family integral membrane protein
FORC37_RS15205	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FORC37_RS15210	COG0640	Transcriptional regulator
FORC37_RS15215	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FORC37_RS15220	COG1280	lysine exporter protein (LysE YggA)
FORC37_RS15225	COG2267	carboxylic ester hydrolase activity
FORC37_RS15230	COG0561	phosphatase activity
FORC37_RS15245	COG3148	PFAM DTW domain containing protein
FORC37_RS15250	COG2199	diguanylate cyclase activity
FORC37_RS15250	COG3287	FIST C domain
FORC37_RS15250	COG2200	EAL domain
FORC37_RS15255	COG1011	Hydrolase
FORC37_RS15260	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FORC37_RS15270	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FORC37_RS15275	COG0019	diaminopimelate decarboxylase activity
FORC37_RS15285	COG1965	Belongs to the frataxin family
FORC37_RS15290	COG3072	Adenylate cyclase
FORC37_RS15295	COG0181	hydroxymethylbilane synthase activity
FORC37_RS15305	COG2959	enzyme of heme biosynthesis
FORC37_RS15315	COG2081	HI0933 family
FORC37_RS15325	COG1528	Iron-storage protein
FORC37_RS15330	COG0589	response to stress
FORC37_RS15345	COG0742	ribosomal rna small subunit methyltransferase
FORC37_RS15350	COG5002	protein histidine kinase activity
FORC37_RS15350	COG5001	Diguanylate cyclase
FORC37_RS15355	COG1522	sequence-specific DNA binding
FORC37_RS15365	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FORC37_RS15370	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FORC37_RS15385	COG0800	Aldolase
FORC37_RS15390	COG2610	gluconate transmembrane transporter activity
FORC37_RS15395	COG3265	gluconokinase activity
FORC37_RS15400	COG0129	dihydroxy-acid dehydratase activity
FORC37_RS15405	COG1609	Transcriptional regulator
FORC37_RS15410	COG0745	RESPONSE REGULATOR receiver
FORC37_RS15420	COG0515	serine threonine protein kinase
FORC37_RS15420	COG2815	serine threonine protein kinase
FORC37_RS15455	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FORC37_RS15460	COG0601	transmembrane transport
FORC37_RS15465	COG4166	transmembrane transport
FORC37_RS15470	COG4172	Belongs to the ABC transporter superfamily
FORC37_RS15510	COG1309	transcriptional regulator
FORC37_RS15515	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FORC37_RS15520	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FORC37_RS15525	COG2960	long-chain fatty acid transporting porin activity
FORC37_RS15530	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FORC37_RS15580	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FORC37_RS15590	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FORC37_RS15595	COG0408	coproporphyrinogen oxidase activity
FORC37_RS15600	COG0009	L-threonylcarbamoyladenylate synthase
FORC37_RS15605	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FORC37_RS15615	COG0551	DNA topoisomerase type I activity
FORC37_RS15620	COG2922	Belongs to the Smg family
FORC37_RS15625	COG0758	DNA mediated transformation
FORC37_RS15635	COG0242	peptide deformylase activity
FORC37_RS15640	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FORC37_RS15645	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FORC37_RS15645	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FORC37_RS15650	COG0569	domain protein
FORC37_RS15655	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FORC37_RS15660	COG1272	protein, Hemolysin III
FORC37_RS15665	COG4326	sporulation control protein
FORC37_RS15675	COG3084	Protein conserved in bacteria
FORC37_RS15685	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FORC37_RS15690	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FORC37_RS15695	COG0204	Acyl-transferase
FORC37_RS15705	COG0606	chelatase, subunit chli
FORC37_RS15715	COG3978	acetolactate synthase activity
FORC37_RS15720	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FORC37_RS15725	COG0129	dihydroxy-acid dehydratase activity
FORC37_RS15735	COG0583	DNA-binding transcription factor activity
FORC37_RS15740	COG2814	Major facilitator Superfamily
FORC37_RS15750	COG0765	amino acid transport
FORC37_RS15760	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FORC37_RS15765	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FORC37_RS15770	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FORC37_RS15775	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FORC37_RS15780	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FORC37_RS15785	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FORC37_RS15795	COG0356	it plays a direct role in the translocation of protons across the membrane
FORC37_RS15800	COG3312	ion transport
FORC37_RS15805	COG1475	DNA binding
FORC37_RS15810	COG1192	Involved in chromosome partitioning
FORC37_RS15815	COG0357	Ribosomal RNA small subunit methyltransferase G
FORC37_RS15820	COG0445	tRNA wobble uridine modification
FORC37_RS15830	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FORC37_RS15840	COG0706	membrane insertase activity
FORC37_RS15850	COG0594	ribonuclease P activity
FORC37_RS15855	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FORC37_RS15860	COG1126	abc transporter atp-binding protein
FORC37_RS15890	COG4608	Belongs to the ABC transporter superfamily
FORC37_RS15895	COG0444	Belongs to the ABC transporter superfamily
FORC37_RS15905	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
FORC37_RS15905	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FORC37_RS15925	COG0217	transcriptional regulatory protein
FORC37_RS15935	COG0583	DNA-binding transcription factor activity
FORC37_RS15945	COG1136	(ABC) transporter
FORC37_RS15950	COG4591	ABC-type transport system involved in lipoprotein release permease component
FORC37_RS15965	COG3275	phosphorelay sensor kinase activity
FORC37_RS15990	COG0786	glutamate:sodium symporter activity
FORC37_RS15995	COG0786	glutamate:sodium symporter activity
FORC37_RS16005	COG0363	glucosamine-6-phosphate deaminase activity
FORC37_RS16020	COG0189	ligase activity
FORC37_RS16040	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FORC37_RS16045	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FORC37_RS16055	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FORC37_RS16070	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FORC37_RS16080	COG1309	transcriptional regulator
FORC37_RS16100	COG3123	guanosine phosphorylase activity
FORC37_RS16110	COG1741	Belongs to the pirin family
FORC37_RS16120	COG5001	Diguanylate cyclase
FORC37_RS16125	COG3706	GGDEF domain
FORC37_RS16135	COG4580	involved in the transport of maltose and maltodextrins
FORC37_RS16180	COG1982	Orn Lys Arg decarboxylase major
FORC37_RS16185	COG0531	amino acid
FORC37_RS16190	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
FORC37_RS16220	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FORC37_RS16225	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
FORC37_RS16230	COG1162	GTPase activity
FORC37_RS16235	COG2847	Copper chaperone PCu(A)C
FORC37_RS16240	COG1999	signal sequence binding
FORC37_RS16265	COG2909	trisaccharide binding
FORC37_RS16270	COG0058	SHG alpha-glucan phosphorylase activity
FORC37_RS16275	COG1640	4-alpha-glucanotransferase
FORC37_RS16290	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FORC37_RS16350	COG1012	belongs to the aldehyde dehydrogenase family
FORC37_RS16355	COG0625	glutathione transferase activity
FORC37_RS16360	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FORC37_RS16365	COG1283	sodium-dependent phosphate transmembrane transporter activity
FORC37_RS16370	COG0612	Peptidase, M16
FORC37_RS16380	COG0583	DNA-binding transcription factor activity
FORC37_RS16385	COG0583	DNA-binding transcription factor activity
FORC37_RS16395	COG0387	Pfam Sodium calcium exchanger
FORC37_RS16400	COG0586	Pfam SNARE associated Golgi protein
FORC37_RS16410	COG0642	Histidine kinase
FORC37_RS16420	COG2199	diguanylate cyclase activity
FORC37_RS16445	COG1609	Transcriptional regulator
FORC37_RS16460	COG0395	ABC-type sugar transport system, permease component
FORC37_RS16465	COG2723	6-phospho-beta-galactosidase activity
FORC37_RS16470	COG3842	ATPase activity
FORC37_RS16475	COG1609	Transcriptional regulator
FORC37_RS16485	COG0747	negative chemotaxis
FORC37_RS16495	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FORC37_RS16500	COG0444	Belongs to the ABC transporter superfamily
FORC37_RS16505	COG4608	Belongs to the ABC transporter superfamily
FORC37_RS16515	COG1609	Transcriptional regulator
FORC37_RS16530	COG4580	involved in the transport of maltose and maltodextrins
FORC37_RS16545	COG1472	Belongs to the glycosyl hydrolase 3 family
FORC37_RS16550	COG0534	Mate efflux family protein
FORC37_RS16560	COG1566	PFAM secretion protein HlyD family protein
FORC37_RS16595	COG0564	pseudouridine synthase activity
FORC37_RS16620	COG1609	Transcriptional regulator
FORC37_RS16650	COG4580	involved in the transport of maltose and maltodextrins
FORC37_RS16665	COG2211	Major facilitator Superfamily
FORC37_RS16675	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FORC37_RS16680	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FORC37_RS16685	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
FORC37_RS16695	COG3708	Transcriptional regulator
FORC37_RS16695	COG2207	Transcriptional regulator
FORC37_RS16750	COG1482	cell wall glycoprotein biosynthetic process
FORC37_RS16755	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC37_RS16755	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FORC37_RS16755	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FORC37_RS16760	COG2207	Transcriptional regulator
FORC37_RS16770	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FORC37_RS16775	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FORC37_RS16785	COG3537	Alpha-1,2-mannosidase
FORC37_RS16790	COG3537	Alpha-1,2-mannosidase
FORC37_RS16800	COG3537	Alpha-1,2-mannosidase
FORC37_RS16805	COG3537	Alpha-1,2-mannosidase
FORC37_RS16810	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FORC37_RS16820	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
FORC37_RS16855	COG3383	formate dehydrogenase (NAD+) activity
FORC37_RS16865	COG0583	DNA-binding transcription factor activity
FORC37_RS16870	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FORC37_RS16875	COG0583	DNA-binding transcription factor activity
FORC37_RS16890	COG0768	penicillin binding
FORC37_RS16905	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
FORC37_RS16925	COG0583	DNA-binding transcription factor activity
FORC37_RS16940	COG0137	argininosuccinate synthase activity
FORC37_RS16950	COG1301	dicarboxylic acid transport
FORC37_RS17000	COG2175	clavaminate synthase activity
FORC37_RS17030	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FORC37_RS17040	COG3706	GGDEF domain
FORC37_RS17055	COG2356	endonuclease I
FORC37_RS17070	COG1368	sulfuric ester hydrolase activity
FORC37_RS17075	COG2194	sulfuric ester hydrolase activity
FORC37_RS17080	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FORC37_RS17085	COG2205	protein histidine kinase activity
FORC37_RS17090	COG0745	RESPONSE REGULATOR receiver
FORC37_RS17105	COG4221	oxidoreductase activity
FORC37_RS17130	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FORC37_RS17135	COG0076	glutamate decarboxylase activity
FORC37_RS17140	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FORC37_RS17150	COG0561	phosphatase activity
FORC37_RS17165	COG0671	phosphoesterase, PA-phosphatase related
FORC37_RS17170	COG0351	phosphomethylpyrimidine kinase
FORC37_RS17235	COG2814	Major facilitator Superfamily
FORC37_RS17250	COG0039	L-malate dehydrogenase activity
FORC37_RS17255	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FORC37_RS17260	COG4771	TonB-dependent receptor
FORC37_RS17280	COG0393	Putative heavy-metal-binding
FORC37_RS17295	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FORC37_RS17325	COG0753	catalase activity
FORC37_RS17345	COG0346	lactoylglutathione lyase activity
FORC37_RS17355	COG2211	Major facilitator Superfamily
FORC37_RS17370	COG3240	lipase activity
FORC37_RS17440	COG3040	lipid binding
FORC37_RS17475	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
FORC37_RS17485	COG2197	response regulator
FORC37_RS17495	COG2197	response regulator
FORC37_RS17505	COG2205	protein histidine kinase activity
FORC37_RS17505	COG0784	Response regulator, receiver
FORC37_RS17510	COG3111	PFAM Bacterial OB fold (BOF) protein
FORC37_RS17520	COG2274	protein secretion by the type I secretion system
FORC37_RS17550	COG0668	transmembrane transport
FORC37_RS17575	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC37_RS17580	COG4946	Tricorn protease homolog
FORC37_RS17580	COG0793	Belongs to the peptidase S41A family
FORC37_RS17595	COG1122	ATPase activity
FORC37_RS17600	COG4720	Psort location CytoplasmicMembrane, score
FORC37_RS17605	COG1566	PFAM secretion protein HlyD family protein
FORC37_RS17630	COG0813	purine-nucleoside phosphorylase activity
FORC37_RS17635	COG3272	Protein of unknown function (DUF1722)
FORC37_RS17640	COG0789	Transcriptional regulator
FORC37_RS17645	COG0415	Belongs to the DNA photolyase family
FORC37_RS17650	COG1388	LysM domain
FORC37_RS17650	COG1376	ErfK ybiS ycfS ynhG family protein
FORC37_RS17660	COG0513	Belongs to the DEAD box helicase family
FORC37_RS17705	COG0573	inorganic phosphate transmembrane transporter activity
FORC37_RS17710	COG0581	inorganic phosphate transmembrane transporter activity
FORC37_RS17715	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FORC37_RS17720	COG5001	Diguanylate cyclase
FORC37_RS17720	COG3706	GGDEF domain
FORC37_RS17720	COG2203	Gaf domain
FORC37_RS17720	COG4251	negative regulation of phosphorylation
FORC37_RS17730	COG2304	oxidoreductase activity
FORC37_RS17750	COG0714	Associated with various cellular activities
FORC37_RS17820	COG1596	polysaccharide export
FORC37_RS17830	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FORC37_RS17835	COG3842	ATPase activity
FORC37_RS17850	COG1175	transmembrane transport
FORC37_RS17855	COG3833	ABC-type maltose transport systems, permease component
FORC37_RS17885	COG2354	Protein conserved in bacteria
FORC37_RS17900	COG3217	Mosc domain protein beta barrel domain protein
FORC37_RS17900	COG0633	Ferredoxin
FORC37_RS17900	COG3217	Mosc domain protein beta barrel domain protein
FORC37_RS17900	COG0633	Ferredoxin
FORC37_RS17905	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FORC37_RS17950	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FORC37_RS17955	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC37_RS17965	COG0848	biopolymer transport protein
FORC37_RS17970	COG0811	peptide transport
FORC37_RS17975	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
FORC37_RS17985	COG3721	Heme iron utilization protein
FORC37_RS17990	COG0748	coenzyme F420 binding
FORC37_RS18000	COG0784	Response regulator, receiver
FORC37_RS18000	COG0835	chemotaxis
FORC37_RS18005	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FORC37_RS18010	COG0589	response to stress
FORC37_RS18015	COG0366	Alpha amylase catalytic
FORC37_RS18025	COG0840	transmembrane signaling receptor activity
FORC37_RS18040	COG3314	Sporulation integral membrane protein YlbJ
FORC37_RS18060	COG0739	heme binding
FORC37_RS18065	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FORC37_RS18080	COG2084	Dehydrogenase
FORC37_RS18105	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FORC37_RS18125	COG0840	transmembrane signaling receptor activity
FORC37_RS18140	COG3706	GGDEF domain
FORC37_RS18145	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FORC37_RS18145	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FORC37_RS18150	COG1765	OsmC-like protein
FORC37_RS18175	COG1011	Hydrolase
FORC37_RS18190	COG0840	transmembrane signaling receptor activity
FORC37_RS18200	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FORC37_RS18215	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FORC37_RS18225	COG1840	ABC-type Fe3 transport system, periplasmic component
FORC37_RS18235	COG3842	ATPase activity
FORC37_RS18255	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FORC37_RS18260	COG0583	DNA-binding transcription factor activity
FORC37_RS18270	COG3104	oligopeptide transport
FORC37_RS18275	COG1760	l-serine dehydratase
FORC37_RS18295	COG1686	Belongs to the peptidase S11 family
FORC37_RS18340	COG4175	Glycine betaine
FORC37_RS18345	COG3059	membrane
FORC37_RS18355	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FORC37_RS18375	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FORC37_RS18385	COG0247	lactate metabolic process
FORC37_RS18390	COG0546	phosphoglycolate phosphatase activity
FORC37_RS18400	COG1619	proteins homologs of microcin C7 resistance protein MccF
FORC37_RS18405	COG2133	pyrroloquinoline quinone binding
FORC37_RS18415	COG1454	alcohol dehydrogenase
FORC37_RS18420	COG0443	Heat shock 70 kDa protein
FORC37_RS18425	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FORC37_RS18455	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FORC37_RS18460	COG3174	membrane
FORC37_RS18485	COG0814	amino acid
FORC37_RS18490	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FORC37_RS18515	COG2962	Rard protein
FORC37_RS18530	COG0671	phosphoesterase, PA-phosphatase related
FORC37_RS18540	COG1288	antiporter activity
FORC37_RS18555	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
FORC37_RS18570	COG2425	protein containing a von Willebrand factor type A (vWA) domain
FORC37_RS18575	COG2315	Protein conserved in bacteria
FORC37_RS18590	COG1869	D-ribose catabolic process
FORC37_RS18600	COG1172	Belongs to the binding-protein-dependent transport system permease family
FORC37_RS18605	COG1879	ABC-type sugar transport system periplasmic component
FORC37_RS18610	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FORC37_RS18615	COG1609	Transcriptional regulator
FORC37_RS18625	COG0835	chemotaxis
FORC37_RS18625	COG0784	Response regulator, receiver
FORC37_RS18635	COG0456	acetyltransferase
FORC37_RS18650	COG1366	Belongs to the anti-sigma-factor antagonist family
FORC37_RS18660	COG2172	sigma factor antagonist activity
FORC37_RS18675	COG3437	response regulator, receiver
FORC37_RS18680	COG0420	3'-5' exonuclease activity
FORC37_RS18685	COG0419	ATPase involved in DNA repair
FORC37_RS18695	COG0583	DNA-binding transcription factor activity
FORC37_RS18715	COG4964	Belongs to the GSP D family
FORC37_RS18800	COG0471	metal ion transport
FORC37_RS18805	COG3290	protein histidine kinase activity
FORC37_RS18815	COG0110	maltose O-acetyltransferase activity
FORC37_RS18835	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC37_RS18840	COG4605	iron ion homeostasis
FORC37_RS18845	COG4604	ABC transporter, ATP-binding protein
FORC37_RS18850	COG0789	Transcriptional regulator
FORC37_RS18880	COG1289	transmembrane transporter activity
FORC37_RS18885	COG0210	DNA helicase
FORC37_RS18890	COG1803	Methylglyoxal synthase
FORC37_RS18895	COG1879	ABC-type sugar transport system periplasmic component
FORC37_RS18900	COG0784	Response regulator, receiver
FORC37_RS18900	COG2198	Histidine kinase
FORC37_RS18900	COG2205	protein histidine kinase activity
FORC37_RS18920	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FORC37_RS18925	COG3005	denitrification pathway
FORC37_RS18950	COG0513	Belongs to the DEAD box helicase family
FORC37_RS18960	COG1716	ATPase activity
FORC37_RS18960	COG5001	Diguanylate cyclase
FORC37_RS18985	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FORC37_RS19000	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
FORC37_RS19005	COG0513	Belongs to the DEAD box helicase family
FORC37_RS19010	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FORC37_RS19015	COG3119	arylsulfatase activity
FORC37_RS19025	COG3119	arylsulfatase activity
FORC37_RS19030	COG0641	radical SAM
FORC37_RS19035	COG0714	Associated with various cellular activities
FORC37_RS19070	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
FORC37_RS19080	COG0641	radical SAM
FORC37_RS19110	COG2814	Major facilitator Superfamily
FORC37_RS19140	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FORC37_RS19150	COG1132	(ABC) transporter
FORC37_RS19175	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FORC37_RS19175	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FORC37_RS19180	COG0509	glycine decarboxylation via glycine cleavage system
FORC37_RS19185	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FORC37_RS19230	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FORC37_RS19230	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FORC37_RS19230	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
FORC37_RS19235	COG1105	Belongs to the carbohydrate kinase PfkB family
FORC37_RS19240	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC37_RS19240	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC37_RS19245	COG1609	Transcriptional regulator
FORC37_RS19270	COG0469	pyruvate kinase activity
FORC37_RS19275	COG2271	Major facilitator Superfamily
FORC37_RS19285	COG4191	Histidine kinase
FORC37_RS19295	COG1979	alcohol dehydrogenase
FORC37_RS19300	COG2207	Transcriptional regulator
FORC37_RS19310	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FORC37_RS19315	COG2759	Belongs to the formate--tetrahydrofolate ligase family
FORC37_RS19320	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FORC37_RS19335	COG0784	Response regulator, receiver
FORC37_RS19335	COG3437	response regulator, receiver
FORC37_RS19340	COG0546	phosphoglycolate phosphatase activity
FORC37_RS19360	COG0513	Belongs to the DEAD box helicase family
FORC37_RS19375	COG3038	cytochrome b561
FORC37_RS19380	COG2353	YceI-like domain
FORC37_RS19385	COG2116	formate transmembrane transporter activity
FORC37_RS19390	COG0583	DNA-binding transcription factor activity
FORC37_RS19400	COG3593	DNA synthesis involved in DNA repair
FORC37_RS19405	COG0737	Belongs to the 5'-nucleotidase family
FORC37_RS19410	COG0861	Integral membrane protein TerC family
FORC37_RS19440	COG2267	carboxylic ester hydrolase activity
FORC37_RS19445	COG2067	long-chain fatty acid transport protein
FORC37_RS19460	COG2050	protein possibly involved in aromatic compounds catabolism
FORC37_RS19470	COG4533	DNA binding
FORC37_RS19480	COG0366	Alpha amylase catalytic
FORC37_RS19485	COG0583	DNA-binding transcription factor activity
FORC37_RS19505	COG0484	heat shock protein binding
FORC37_RS19520	COG5001	Diguanylate cyclase
FORC37_RS19520	COG1716	ATPase activity
FORC37_RS19525	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FORC37_RS19535	COG4181	ATPase activity
FORC37_RS19540	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FORC37_RS19545	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FORC37_RS19545	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FORC37_RS19550	COG1984	allophanate hydrolase subunit 2
FORC37_RS19555	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FORC37_RS19570	COG3447	MASE1 domain protein
FORC37_RS19570	COG5002	protein histidine kinase activity
FORC37_RS19570	COG5001	Diguanylate cyclase
FORC37_RS19580	COG0583	DNA-binding transcription factor activity
FORC37_RS19585	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC37_RS19585	COG1042	CoA-binding domain protein
FORC37_RS19585	COG0045	succinate-CoA ligase (ADP-forming) activity
FORC37_RS19595	COG1181	Belongs to the D-alanine--D-alanine ligase family
FORC37_RS19605	COG0023	Translation Initiation Factor
FORC37_RS19680	COG3140	Belongs to the UPF0181 family
FORC37_RS19695	COG0745	RESPONSE REGULATOR receiver
FORC37_RS19705	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FORC37_RS19710	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FORC37_RS19735	COG2199	diguanylate cyclase activity
FORC37_RS19745	COG1846	Transcriptional regulator
FORC37_RS19750	COG0697	spore germination
FORC37_RS19760	COG4149	molybdate abc transporter
FORC37_RS19765	COG0725	ABC transporter, periplasmic molybdate-binding protein
FORC37_RS19785	COG0189	ligase activity
FORC37_RS19785	COG4067	protein conserved in archaea
FORC37_RS19795	COG0840	transmembrane signaling receptor activity
FORC37_RS19800	COG0602	queuosine metabolic process
FORC37_RS19805	COG1328	CTP reductase activity
FORC37_RS19860	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FORC37_RS19865	COG3118	belongs to the thioredoxin family
FORC37_RS19870	COG0477	Major facilitator Superfamily
FORC37_RS19880	COG0534	Mate efflux family protein
FORC37_RS19900	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FORC37_RS19915	COG0848	biopolymer transport protein
FORC37_RS19920	COG0811	peptide transport
FORC37_RS19925	COG0811	peptide transport
FORC37_RS19960	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FORC37_RS19965	COG0840	transmembrane signaling receptor activity
FORC37_RS19995	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FORC37_RS20005	COG2203	Gaf domain
FORC37_RS20005	COG3706	GGDEF domain
FORC37_RS20005	COG5001	Diguanylate cyclase
FORC37_RS20005	COG4251	negative regulation of phosphorylation
FORC37_RS20015	COG0010	Belongs to the arginase family
FORC37_RS20020	COG0513	Belongs to the DEAD box helicase family
FORC37_RS20030	COG0523	cobalamin synthesis protein
FORC37_RS20040	COG2199	diguanylate cyclase activity
FORC37_RS20055	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FORC37_RS20055	COG2146	nitrite reductase [NAD(P)H] activity
FORC37_RS20060	COG1116	anion transmembrane transporter activity
FORC37_RS20065	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FORC37_RS20070	COG1116	anion transmembrane transporter activity
FORC37_RS20070	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FORC37_RS20075	COG3707	response regulator
FORC37_RS20090	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FORC37_RS20090	COG1648	precorrin-2 dehydrogenase activity
FORC37_RS20100	COG0456	acetyltransferase
FORC37_RS20105	COG0366	Alpha amylase catalytic
FORC37_RS20110	COG0840	transmembrane signaling receptor activity
FORC37_RS20115	COG0840	transmembrane signaling receptor activity
FORC37_RS20135	COG2271	Major facilitator Superfamily
FORC37_RS20140	COG0584	glycerophosphoryl diester phosphodiesterase
FORC37_RS20145	COG0312	modulator of DNA gyrase
FORC37_RS20150	COG0312	modulator of DNA gyrase
FORC37_RS20160	COG3069	C4-dicarboxylate transmembrane transporter activity
FORC37_RS20165	COG1704	LemA family
FORC37_RS20170	COG0501	Belongs to the peptidase M48B family
FORC37_RS20185	COG3209	COG3209 Rhs family protein
FORC37_RS20265	COG0631	protein serine/threonine phosphatase activity
FORC37_RS20300	COG0515	serine threonine protein kinase
FORC37_RS20300	COG2815	serine threonine protein kinase
FORC37_RS20320	COG3530	Putative quorum-sensing-regulated virulence factor
FORC37_RS20340	COG2154	pterin-4-alpha-carbinolamine dehydratase
FORC37_RS20345	COG3186	Phenylalanine-4-hydroxylase
FORC37_RS20350	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FORC37_RS20375	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
FORC37_RS20385	COG4191	Histidine kinase
FORC37_RS20385	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC37_RS20390	COG3437	response regulator, receiver
FORC37_RS20390	COG0784	Response regulator, receiver
FORC37_RS20445	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
FORC37_RS20445	COG3064	Membrane
FORC37_RS20445	COG1073	alpha beta
FORC37_RS20450	COG2994	toxin metabolic process
FORC37_RS20475	COG1028	Short-chain dehydrogenase reductase Sdr
FORC37_RS20485	COG1024	Enoyl-CoA hydratase
FORC37_RS20490	COG1024	Enoyl-CoA hydratase
FORC37_RS20495	COG1960	acyl-CoA dehydrogenase activity
FORC37_RS20505	COG0183	Belongs to the thiolase family
FORC37_RS20515	COG1960	acyl-CoA dehydrogenase activity
FORC37_RS20520	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FORC37_RS20545	COG1278	Cold shock
FORC37_RS20560	COG1309	transcriptional regulator
FORC37_RS20565	COG2130	NADP-dependent
FORC37_RS20585	COG2197	response regulator
FORC37_RS20590	COG3851	Histidine kinase
FORC37_RS20595	COG2271	Major facilitator Superfamily
FORC37_RS20600	COG1482	cell wall glycoprotein biosynthetic process
FORC37_RS20610	COG2199	diguanylate cyclase activity
FORC37_RS20610	COG2203	Gaf domain
FORC37_RS20620	COG3036	rescue of stalled ribosome
FORC37_RS20625	COG1278	Cold shock
FORC37_RS20655	COG0545	Peptidyl-prolyl cis-trans isomerase
FORC37_RS20660	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FORC37_RS20665	COG0840	transmembrane signaling receptor activity
FORC37_RS20685	COG2195	Cleaves the N-terminal amino acid of tripeptides
FORC37_RS20695	COG4989	oxidoreductase activity
FORC37_RS20720	COG0038	chloride channel
FORC37_RS20730	COG1914	H( )-stimulated, divalent metal cation uptake system
FORC37_RS20735	COG0302	gtp cyclohydrolase
FORC37_RS20740	COG0303	'Molybdopterin
FORC37_RS20745	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FORC37_RS20755	COG2897	thiosulfate sulfurtransferase activity
FORC37_RS20775	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FORC37_RS20795	COG0840	transmembrane signaling receptor activity
FORC37_RS20800	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FORC37_RS20805	COG2885	chlorophyll binding
FORC37_RS20810	COG0109	protoheme IX farnesyltransferase activity
FORC37_RS20815	COG1612	heme a metabolic process
FORC37_RS20840	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
FORC37_RS20845	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FORC37_RS20850	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FORC37_RS20855	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FORC37_RS20865	COG1280	lysine exporter protein (LysE YggA)
FORC37_RS20890	COG1846	Transcriptional regulator
FORC37_RS20895	COG1764	response to oxidative stress
FORC37_RS20905	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FORC37_RS20915	COG3300	MHYT domain
FORC37_RS20915	COG5001	Diguanylate cyclase
FORC37_RS20920	COG0697	spore germination
FORC37_RS20940	COG2814	Major facilitator Superfamily
FORC37_RS20945	COG0583	DNA-binding transcription factor activity
FORC37_RS20950	COG4251	negative regulation of phosphorylation
FORC37_RS20950	COG2203	Gaf domain
FORC37_RS20950	COG5001	Diguanylate cyclase
FORC37_RS20950	COG3706	GGDEF domain
FORC37_RS20955	COG0251	oxidation-reduction process
FORC37_RS20970	COG4145	pantothenate transmembrane transporter activity
FORC37_RS20980	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
FORC37_RS20990	COG1737	Transcriptional regulator
FORC37_RS20990	COG0837	glucose binding
FORC37_RS21000	COG1131	(ABC) transporter
FORC37_RS21005	COG0842	Transport permease protein
FORC37_RS21035	COG1846	Transcriptional regulator
FORC37_RS21050	COG0513	Belongs to the DEAD box helicase family
FORC37_RS21075	COG3568	Endonuclease Exonuclease Phosphatase
FORC37_RS21090	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FORC37_RS21140	COG0516	GMP reductase activity
FORC37_RS21265	COG4974	Belongs to the 'phage' integrase family
FORC37_RS21300	COG0741	lytic transglycosylase activity
FORC37_RS21330	COG0330	HflC and HflK could
FORC37_RS21350	COG3457	Alanine racemase
FORC37_RS21375	COG3604	Transcriptional regulator
FORC37_RS21385	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FORC37_RS21395	COG4208	sulfate ABC transporter
FORC37_RS21420	COG0628	permease
FORC37_RS21455	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FORC37_RS21465	COG1566	PFAM secretion protein HlyD family protein
FORC37_RS21505	COG0516	GMP reductase activity
FORC37_RS21515	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FORC37_RS21515	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FORC37_RS21535	COG2197	response regulator
FORC37_RS21540	COG3850	Histidine kinase
FORC37_RS21545	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FORC37_RS21555	COG0243	molybdopterin cofactor binding
FORC37_RS21565	COG3005	denitrification pathway
FORC37_RS21575	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
FORC37_RS21580	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
FORC37_RS21585	COG1737	Transcriptional regulator
FORC37_RS21590	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FORC37_RS21595	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FORC37_RS21600	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FORC37_RS21605	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FORC37_RS21610	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
FORC37_RS21615	COG1940	carbohydrate kinase activity
FORC37_RS21620	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FORC37_RS21640	COG0183	Belongs to the thiolase family
FORC37_RS21650	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FORC37_RS21655	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FORC37_RS21715	COG2827	Endonuclease containing a URI domain
FORC37_RS21720	COG3132	Protein of unknown function, DUF480
FORC37_RS21730	COG2926	Belongs to the UPF0265 family
FORC37_RS21740	COG0534	Mate efflux family protein
FORC37_RS21745	COG0784	Response regulator, receiver
FORC37_RS21745	COG2205	protein histidine kinase activity
FORC37_RS21745	COG5002	protein histidine kinase activity
FORC37_RS21770	COG0583	DNA-binding transcription factor activity
FORC37_RS21775	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FORC37_RS21795	COG1522	sequence-specific DNA binding
FORC37_RS21805	COG0531	amino acid
FORC37_RS21810	COG0121	glutamine amidotransferase
FORC37_RS21825	COG2205	protein histidine kinase activity
FORC37_RS21830	COG0745	RESPONSE REGULATOR receiver
FORC37_RS21855	COG2239	Acts as a magnesium transporter
FORC37_RS21865	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FORC37_RS21870	COG0402	S-adenosylhomocysteine deaminase activity
FORC37_RS21875	COG1067	ATP-dependent peptidase activity
FORC37_RS21885	COG4172	Belongs to the ABC transporter superfamily
FORC37_RS21890	COG1505	serine-type exopeptidase activity
FORC37_RS21895	COG0583	DNA-binding transcription factor activity
FORC37_RS21900	COG1620	l-lactate permease
FORC37_RS21910	COG1139	Iron-sulfur cluster binding protein
FORC37_RS21940	COG2814	Major facilitator Superfamily
FORC37_RS21980	COG5001	Diguanylate cyclase
FORC37_RS21995	COG3015	lipoprotein NlpE involved in copper resistance
FORC37_RS22000	COG1126	abc transporter atp-binding protein
FORC37_RS22005	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC37_RS22010	COG4215	(ABC) transporter
FORC37_RS22015	COG4160	amino acid transport
FORC37_RS22030	COG5002	protein histidine kinase activity
FORC37_RS22030	COG5001	Diguanylate cyclase
FORC37_RS22035	COG2755	lipolytic protein G-D-S-L family
FORC37_RS22045	COG0840	transmembrane signaling receptor activity
FORC37_RS22050	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC37_RS22065	COG2977	Belongs to the P-Pant transferase superfamily
FORC37_RS22080	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FORC37_RS22085	COG1028	Short-chain dehydrogenase reductase Sdr
FORC37_RS22090	COG1169	isochorismate synthase
FORC37_RS22095	COG1021	2,3-dihydroxybenzoate-AMP ligase
FORC37_RS22115	COG1021	2,3-dihydroxybenzoate-AMP ligase
FORC37_RS22125	COG4607	ABC-type enterochelin transport system periplasmic component
FORC37_RS22130	COG1629	transport
FORC37_RS22130	COG4774	siderophore transport
FORC37_RS22140	COG0189	ligase activity
FORC37_RS22145	COG4067	protein conserved in archaea
FORC37_RS22145	COG0189	ligase activity
FORC37_RS22170	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FORC37_RS22180	COG5002	protein histidine kinase activity
FORC37_RS22185	COG0745	RESPONSE REGULATOR receiver
FORC37_RS22205	COG3033	Beta-eliminating lyase
FORC37_RS22210	COG0814	amino acid
FORC37_RS22215	COG0488	(ABC) transporter
FORC37_RS22230	COG1609	Transcriptional regulator
FORC37_RS22235	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC37_RS22260	COG1253	flavin adenine dinucleotide binding
FORC37_RS22270	COG1012	belongs to the aldehyde dehydrogenase family
FORC37_RS22275	COG3284	Transcriptional regulator
FORC37_RS22285	COG1879	ABC-type sugar transport system periplasmic component
FORC37_RS22290	COG0625	glutathione transferase activity
FORC37_RS22300	COG0384	phenazine biosynthesis protein PhzF
FORC37_RS22305	COG2197	response regulator
FORC37_RS22315	COG0673	inositol 2-dehydrogenase activity
FORC37_RS22340	COG2015	COG2015, Alkyl sulfatase and related hydrolases
FORC37_RS22350	COG0583	DNA-binding transcription factor activity
FORC37_RS22355	COG2194	sulfuric ester hydrolase activity
FORC37_RS22375	COG0798	PFAM Bile acid sodium symporter
FORC37_RS22380	COG0640	Transcriptional regulator
FORC37_RS22395	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FORC37_RS22400	COG0700	Nucleoside recognition
FORC37_RS22405	COG3366	ferrous iron transmembrane transporter activity
FORC37_RS22415	COG0366	Alpha amylase catalytic
FORC37_RS22425	COG0800	Aldolase
FORC37_RS22430	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FORC37_RS22435	COG0697	spore germination
FORC37_RS22455	COG1917	Cupin 2, conserved barrel domain protein
FORC37_RS22465	COG1028	Short-chain dehydrogenase reductase Sdr
FORC37_RS22495	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FORC37_RS22495	COG3153	acetyltransferase
FORC37_RS22515	COG0668	transmembrane transport
FORC37_RS22550	COG0494	nUDIX hydrolase
FORC37_RS22555	COG1881	PFAM PEBP family protein
FORC37_RS22560	COG2207	Transcriptional regulator
FORC37_RS22565	COG3046	protein related to deoxyribodipyrimidine photolyase
FORC37_RS22595	COG0454	-acetyltransferase
FORC37_RS22605	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FORC37_RS22630	COG1858	cytochrome C peroxidase
FORC37_RS22650	COG2814	Major facilitator Superfamily
FORC37_RS22670	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
FORC37_RS22680	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FORC37_RS22690	COG0583	DNA-binding transcription factor activity
FORC37_RS22710	COG0513	Belongs to the DEAD box helicase family
FORC37_RS22745	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FORC37_RS22755	COG1357	PFAM Pentapeptide repeats (8 copies)
FORC37_RS22775	COG3437	response regulator, receiver
FORC37_RS22785	COG0579	oxidoreductase
FORC37_RS22815	COG2015	COG2015, Alkyl sulfatase and related hydrolases
FORC37_RS22830	COG2205	protein histidine kinase activity
FORC37_RS22865	COG3706	GGDEF domain
FORC37_RS22880	COG2176	DNA-directed DNA polymerase activity
FORC37_RS22885	COG1136	(ABC) transporter
FORC37_RS22885	COG0577	efflux transmembrane transporter activity
FORC37_RS22890	COG0577	efflux transmembrane transporter activity
FORC37_RS22890	COG1136	(ABC) transporter
FORC37_RS22925	COG1120	ATPase activity
FORC37_RS22930	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FORC37_RS22950	COG0488	(ABC) transporter
FORC37_RS22965	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC37_RS22970	COG3716	PTS system mannose fructose sorbose family IID component
FORC37_RS22980	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC37_RS22985	COG2222	sugar isomerase
FORC37_RS22995	COG1349	DNA-binding transcription factor activity
FORC37_RS23005	COG1349	DNA-binding transcription factor activity
FORC37_RS23010	COG0697	spore germination
FORC37_RS23015	COG2207	Transcriptional regulator
FORC37_RS23030	COG2015	COG2015, Alkyl sulfatase and related hydrolases
FORC37_RS23055	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FORC37_RS23060	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FORC37_RS23080	COG0840	transmembrane signaling receptor activity
FORC37_RS23095	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FORC37_RS23115	COG0583	DNA-binding transcription factor activity
FORC37_RS23120	COG1486	melibiose metabolic process
FORC37_RS23140	COG2258	MOSC domain
FORC37_RS23150	COG0463	Glycosyl transferase, family 2
FORC37_RS23165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FORC37_RS23200	COG0513	Belongs to the DEAD box helicase family
FORC37_RS23210	COG2186	Transcriptional regulator
FORC37_RS23220	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FORC37_RS23230	COG0246	Mannitol dehydrogenase
FORC37_RS23235	COG1904	glucuronate isomerase
FORC37_RS23240	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FORC37_RS23245	COG0800	Aldolase
FORC37_RS23260	COG1028	Short-chain dehydrogenase reductase Sdr
FORC37_RS23265	COG2999	glutathione oxidoreductase activity
FORC37_RS23270	COG1902	pentaerythritol trinitrate reductase activity
FORC37_RS23300	COG0561	phosphatase activity
FORC37_RS23305	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
FORC37_RS23310	COG3623	hexulose-6-phosphate isomerase
FORC37_RS23325	COG1132	(ABC) transporter
FORC37_RS23330	COG5492	domain, Protein
FORC37_RS23335	COG5426	von Willebrand factor, type A
FORC37_RS23345	COG1028	Short-chain dehydrogenase reductase Sdr
FORC37_RS23355	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FORC37_RS23360	COG0659	secondary active sulfate transmembrane transporter activity
FORC37_RS23390	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FORC37_RS23395	COG0601	transmembrane transport
FORC37_RS23405	COG0747	negative chemotaxis
FORC37_RS23415	COG3119	arylsulfatase activity
FORC37_RS23420	COG0641	radical SAM
FORC37_RS23425	COG3119	arylsulfatase activity
FORC37_RS23430	COG3119	arylsulfatase activity
FORC37_RS23435	COG5492	domain, Protein
FORC37_RS23460	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FORC37_RS23490	COG0259	pyridoxamine-phosphate oxidase activity
FORC37_RS23500	COG2204	response regulator
FORC37_RS23530	COG3069	C4-dicarboxylate transmembrane transporter activity
FORC37_RS23535	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FORC37_RS23550	COG0459	protein refolding
FORC37_RS23555	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FORC37_RS23560	COG0110	maltose O-acetyltransferase activity
FORC37_RS23575	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FORC37_RS23575	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FORC37_RS23580	COG1737	Transcriptional regulator
FORC37_RS23590	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FORC37_RS23595	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC37_RS23595	COG1263	PTS System
FORC37_RS23605	COG5001	Diguanylate cyclase
FORC37_RS23605	COG2203	Gaf domain
FORC37_RS23605	COG3706	GGDEF domain
FORC37_RS23605	COG4251	negative regulation of phosphorylation
FORC37_RS23610	COG0406	alpha-ribazole phosphatase activity
FORC37_RS23625	COG2814	Major facilitator Superfamily
FORC37_RS23675	COG0840	transmembrane signaling receptor activity
FORC37_RS23680	COG2201	protein-glutamate methylesterase activity
FORC37_RS23685	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
FORC37_RS23690	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FORC37_RS23695	COG0840	transmembrane signaling receptor activity
FORC37_RS23700	COG0835	chemotaxis
FORC37_RS23715	COG0745	RESPONSE REGULATOR receiver
FORC37_RS23725	COG1444	tRNA N-acetyltransferase activity
FORC37_RS23790	COG0454	-acetyltransferase
FORC37_RS23965	COG4628	conserved protein (DUF2132)
FORC37_RS24100	COG0454	-acetyltransferase