locus-tag	class	description
FORC54_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FORC54_RS00010	COG0592	DNA-directed DNA polymerase activity
FORC54_RS00020	COG0187	DNA topoisomerase II activity
FORC54_RS00025	COG0071	Belongs to the small heat shock protein (HSP20) family
FORC54_RS00035	COG3977	Valine--pyruvate aminotransferase
FORC54_RS00045	COG0751	glycine-tRNA ligase activity
FORC54_RS00050	COG0752	glycyl-tRNA synthetase alpha subunit
FORC54_RS00055	COG2119	membrane
FORC54_RS00065	COG0425	Belongs to the sulfur carrier protein TusA family
FORC54_RS00080	COG0604	alcohol dehydrogenase
FORC54_RS00085	COG0183	Belongs to the thiolase family
FORC54_RS00095	COG1739	Uncharacterized protein family UPF0029
FORC54_RS00100	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FORC54_RS00105	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
FORC54_RS00140	COG2132	Multicopper oxidase
FORC54_RS00145	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FORC54_RS00150	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FORC54_RS00155	COG0352	thiamine-phosphate diphosphorylase activity
FORC54_RS00160	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FORC54_RS00170	COG2022	thiamine diphosphate biosynthetic process
FORC54_RS00180	COG0006	proline dipeptidase activity
FORC54_RS00180	COG0006	proline dipeptidase activity
FORC54_RS00220	COG0210	DNA helicase
FORC54_RS00230	COG1280	lysine exporter protein (LysE YggA)
FORC54_RS00240	COG2962	Rard protein
FORC54_RS00245	COG0514	ATP-dependent DNA helicase (RecQ)
FORC54_RS00255	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FORC54_RS00260	COG0248	Ppx GppA phosphatase
FORC54_RS00270	COG3118	belongs to the thioredoxin family
FORC54_RS00350	COG3335	DDE superfamily endonuclease
FORC54_RS00370	COG1322	Protein conserved in bacteria
FORC54_RS00375	COG2226	methyltransferase
FORC54_RS00380	COG3165	ubiquinone biosynthetic process from chorismate
FORC54_RS00390	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FORC54_RS00395	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FORC54_RS00400	COG0805	protein transport
FORC54_RS00405	COG0084	hydrolase, TatD family'
FORC54_RS00415	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FORC54_RS00415	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FORC54_RS00420	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FORC54_RS00450	COG5001	Diguanylate cyclase
FORC54_RS00450	COG3300	MHYT domain
FORC54_RS00460	COG3852	Histidine kinase
FORC54_RS00470	COG0174	glutamine synthetase
FORC54_RS00480	COG1217	gtp-binding protein TYPA
FORC54_RS00495	COG1295	ribonuclease BN
FORC54_RS00500	COG1490	D-aminoacyl-tRNA deacylase activity
FORC54_RS00505	COG0456	acetyltransferase
FORC54_RS00520	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FORC54_RS00525	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FORC54_RS00530	COG3031	protein transport across the cell outer membrane
FORC54_RS00540	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FORC54_RS00545	COG1459	type II secretion system
FORC54_RS00550	COG2165	general secretion pathway protein
FORC54_RS00555	COG2165	general secretion pathway protein
FORC54_RS00560	COG2165	general secretion pathway protein
FORC54_RS00565	COG4795	General secretion pathway protein
FORC54_RS00570	COG3156	type II secretion system protein K
FORC54_RS00575	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
FORC54_RS00580	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
FORC54_RS00590	COG1218	3'(2'),5'-bisphosphate nucleotidase
FORC54_RS00595	COG0494	nUDIX hydrolase
FORC54_RS00600	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FORC54_RS00600	COG0316	Belongs to the HesB IscA family
FORC54_RS00610	COG0596	Alpha beta hydrolase
FORC54_RS00620	COG2183	response to ionizing radiation
FORC54_RS00630	COG4221	oxidoreductase activity
FORC54_RS00650	COG1129	ABC transporter
FORC54_RS00655	COG1172	Belongs to the binding-protein-dependent transport system permease family
FORC54_RS00660	COG1472	Belongs to the glycosyl hydrolase 3 family
FORC54_RS00675	COG2233	PERMEase
FORC54_RS00680	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FORC54_RS00685	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FORC54_RS00690	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FORC54_RS00695	COG1758	RNA polymerase activity
FORC54_RS00700	COG0194	GDP metabolic process
FORC54_RS00715	COG0848	biopolymer transport protein
FORC54_RS00720	COG0811	peptide transport
FORC54_RS00725	COG0811	peptide transport
FORC54_RS00735	COG4206	TonB-dependent receptor
FORC54_RS00740	COG4174	ABC transporter (Permease)
FORC54_RS00745	COG4239	(ABC) transporter, permease
FORC54_RS00750	COG0747	negative chemotaxis
FORC54_RS00755	COG0444	Belongs to the ABC transporter superfamily
FORC54_RS00760	COG4608	Belongs to the ABC transporter superfamily
FORC54_RS00790	COG1561	YicC-like family, N-terminal region
FORC54_RS00795	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FORC54_RS00805	COG1560	Kdo2-lipid A biosynthetic process
FORC54_RS00810	COG1309	transcriptional regulator
FORC54_RS00825	COG2003	Belongs to the UPF0758 family
FORC54_RS00830	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FORC54_RS00835	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FORC54_RS00845	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FORC54_RS00855	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FORC54_RS00860	COG0859	PFAM glycosyl transferase family 9
FORC54_RS00865	COG0463	Glycosyl transferase, family 2
FORC54_RS00870	COG0859	PFAM glycosyl transferase family 9
FORC54_RS00875	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FORC54_RS00880	COG3642	lipopolysaccharide core region biosynthetic process
FORC54_RS00905	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FORC54_RS00915	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FORC54_RS00920	COG0107	imidazoleglycerol-phosphate synthase activity
FORC54_RS00925	COG1083	cytidylyl-transferase
FORC54_RS00935	COG2089	acid synthase
FORC54_RS00950	COG0859	PFAM glycosyl transferase family 9
FORC54_RS00965	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FORC54_RS01000	COG1596	polysaccharide export
FORC54_RS01025	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FORC54_RS01045	COG0110	maltose O-acetyltransferase activity
FORC54_RS01050	COG0110	maltose O-acetyltransferase activity
FORC54_RS01070	COG0438	transferase activity, transferring glycosyl groups
FORC54_RS01085	COG1482	cell wall glycoprotein biosynthetic process
FORC54_RS01095	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FORC54_RS01100	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FORC54_RS01120	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FORC54_RS01145	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FORC54_RS01150	COG0088	Forms part of the polypeptide exit tunnel
FORC54_RS01155	COG0089	rRNA binding
FORC54_RS01160	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FORC54_RS01165	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FORC54_RS01175	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FORC54_RS01180	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FORC54_RS01185	COG0255	Belongs to the universal ribosomal protein uL29 family
FORC54_RS01190	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FORC54_RS01195	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FORC54_RS01200	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FORC54_RS01205	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FORC54_RS01210	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FORC54_RS01215	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FORC54_RS01220	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FORC54_RS01225	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FORC54_RS01230	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FORC54_RS01235	COG1841	ribosomal large subunit assembly
FORC54_RS01240	COG0200	Binds to the 23S rRNA
FORC54_RS01245	COG0201	protein transport
FORC54_RS01250	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FORC54_RS01255	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FORC54_RS01260	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FORC54_RS01265	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FORC54_RS01270	COG0202	RNA polymerase activity
FORC54_RS01275	COG0203	ribosomal protein L17
FORC54_RS01285	COG0545	Peptidyl-prolyl cis-trans isomerase
FORC54_RS01290	COG3266	domain, Protein
FORC54_RS01290	COG3061	Opacity-associated protein A
FORC54_RS01300	COG2153	protein acetylation
FORC54_RS01310	COG0737	Belongs to the 5'-nucleotidase family
FORC54_RS01315	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FORC54_RS01315	COG1648	precorrin-2 dehydrogenase activity
FORC54_RS01320	COG0175	sulfate reduction
FORC54_RS01325	COG2895	sulfate adenylyltransferase (ATP) activity
FORC54_RS01330	COG0471	metal ion transport
FORC54_RS01330	COG3273	potassium ion transport
FORC54_RS01335	COG0529	Catalyzes the synthesis of activated sulfate
FORC54_RS01355	COG1136	(ABC) transporter
FORC54_RS01355	COG0577	efflux transmembrane transporter activity
FORC54_RS01370	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
FORC54_RS01385	COG0729	surface antigen
FORC54_RS01390	COG2911	Protein conserved in bacteria
FORC54_RS01395	COG2105	PFAM AIG2 family protein
FORC54_RS01405	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FORC54_RS01410	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
FORC54_RS01415	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FORC54_RS01420	COG0163	prenyltransferase activity
FORC54_RS01425	COG4143	(ABC) transporter
FORC54_RS01430	COG1178	ABC-type Fe3 transport system permease component
FORC54_RS01435	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FORC54_RS01440	COG3028	Belongs to the UPF0307 family
FORC54_RS01445	COG0312	modulator of DNA gyrase
FORC54_RS01450	COG2239	Acts as a magnesium transporter
FORC54_RS01455	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC54_RS01460	COG1660	Displays ATPase and GTPase activities
FORC54_RS01465	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC54_RS01470	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FORC54_RS01480	COG1137	ATPase activity
FORC54_RS01485	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FORC54_RS01495	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FORC54_RS01500	COG0517	IMP dehydrogenase activity
FORC54_RS01500	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FORC54_RS01510	COG1127	ABC transporter
FORC54_RS01515	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FORC54_RS01520	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FORC54_RS01525	COG2854	intermembrane phospholipid transfer
FORC54_RS01535	COG5007	Belongs to the BolA IbaG family
FORC54_RS01545	COG0204	Acyl-transferase
FORC54_RS01550	COG0589	response to stress
FORC54_RS01560	COG2358	TRAP transporter, solute receptor (TAXI family
FORC54_RS01565	COG1438	arginine binding
FORC54_RS01570	COG0039	L-malate dehydrogenase activity
FORC54_RS01575	COG0142	geranyltranstransferase activity
FORC54_RS01580	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FORC54_RS01585	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FORC54_RS01595	COG2966	Psort location CytoplasmicMembrane, score
FORC54_RS01600	COG3610	response to peptide
FORC54_RS01615	COG2967	ApaG domain
FORC54_RS01620	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FORC54_RS01625	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FORC54_RS01650	COG0066	3-isopropylmalate dehydratase activity
FORC54_RS01660	COG0473	3-isopropylmalate dehydrogenase activity
FORC54_RS01665	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FORC54_RS01690	COG1022	Amp-dependent synthetase and ligase
FORC54_RS01695	COG0028	Belongs to the TPP enzyme family
FORC54_RS01700	COG0440	acetolactate synthase activity
FORC54_RS01705	COG3706	GGDEF domain
FORC54_RS01720	COG1349	DNA-binding transcription factor activity
FORC54_RS01725	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FORC54_RS01730	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FORC54_RS01745	COG3550	peptidyl-serine autophosphorylation
FORC54_RS01760	COG2207	Transcriptional regulator
FORC54_RS01830	COG1181	Belongs to the D-alanine--D-alanine ligase family
FORC54_RS01915	COG3547	Transposase (IS116 IS110 IS902 family)
FORC54_RS01920	COG2003	Belongs to the UPF0758 family
FORC54_RS01935	COG3339	Conserved Protein
FORC54_RS01985	COG0582	viral genome integration into host DNA
FORC54_RS02005	COG1610	YqeY-like protein
FORC54_RS02010	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FORC54_RS02015	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FORC54_RS02020	COG0596	Alpha beta hydrolase
FORC54_RS02030	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FORC54_RS02035	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FORC54_RS02040	COG1968	undecaprenyl-diphosphatase activity
FORC54_RS02045	COG0617	tRNA 3'-terminal CCA addition
FORC54_RS02050	COG3267	Type II secretory pathway component ExeA
FORC54_RS02050	COG3409	Peptidoglycan-binding domain 1 protein
FORC54_RS02055	COG4991	sh3 domain protein
FORC54_RS02060	COG0306	phosphate transporter
FORC54_RS02065	COG1392	Phosphate transport regulator
FORC54_RS02070	COG3025	triphosphatase activity
FORC54_RS02075	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FORC54_RS02085	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FORC54_RS02095	COG1538	Outer membrane efflux protein
FORC54_RS02100	COG0494	nUDIX hydrolase
FORC54_RS02105	COG3151	Protein conserved in bacteria
FORC54_RS02115	COG3150	esterase
FORC54_RS02130	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FORC54_RS02135	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FORC54_RS02140	COG3105	Protein conserved in bacteria
FORC54_RS02145	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FORC54_RS02155	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FORC54_RS02160	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FORC54_RS02165	COG0723	plastoquinol--plastocyanin reductase activity
FORC54_RS02170	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FORC54_RS02175	COG2857	Cytochrome c1
FORC54_RS02180	COG0625	glutathione transferase activity
FORC54_RS02185	COG2969	positive regulation of protein catabolic process
FORC54_RS02190	COG2823	Periplasmic or secreted lipoprotein
FORC54_RS02195	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FORC54_RS02200	COG0792	nuclease activity
FORC54_RS02205	COG3107	peptidoglycan biosynthetic process
FORC54_RS02210	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FORC54_RS02220	COG0275	rRNA processing
FORC54_RS02225	COG3116	cell division
FORC54_RS02230	COG0768	penicillin binding
FORC54_RS02240	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FORC54_RS02245	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FORC54_RS02250	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FORC54_RS02255	COG0772	Belongs to the SEDS family
FORC54_RS02265	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FORC54_RS02270	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FORC54_RS02275	COG0849	cell division
FORC54_RS02280	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FORC54_RS02285	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
FORC54_RS02295	COG0653	protein targeting
FORC54_RS02300	COG0494	nUDIX hydrolase
FORC54_RS02310	COG0505	Belongs to the CarA family
FORC54_RS02315	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FORC54_RS02330	COG0730	response to heat
FORC54_RS02335	COG0583	DNA-binding transcription factor activity
FORC54_RS02340	COG2860	membrane
FORC54_RS02345	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FORC54_RS02355	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FORC54_RS02365	COG0493	'glutamate synthase
FORC54_RS02370	COG0067	glutamate synthase
FORC54_RS02370	COG0070	glutamate synthase
FORC54_RS02370	COG0069	glutamate synthase activity
FORC54_RS02380	COG0070	glutamate synthase
FORC54_RS02380	COG0069	glutamate synthase activity
FORC54_RS02380	COG0067	glutamate synthase
FORC54_RS02385	COG1242	4 iron, 4 sulfur cluster binding
FORC54_RS02390	COG5001	Diguanylate cyclase
FORC54_RS02390	COG2203	Gaf domain
FORC54_RS02390	COG4251	negative regulation of phosphorylation
FORC54_RS02390	COG3706	GGDEF domain
FORC54_RS02395	COG5002	protein histidine kinase activity
FORC54_RS02395	COG0784	Response regulator, receiver
FORC54_RS02395	COG2198	Histidine kinase
FORC54_RS02405	COG0745	RESPONSE REGULATOR receiver
FORC54_RS02420	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FORC54_RS02435	COG0083	homoserine kinase activity
FORC54_RS02440	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FORC54_RS02445	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
FORC54_RS02455	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FORC54_RS02470	COG1115	amino acid carrier protein
FORC54_RS02475	COG3022	response to hydroperoxide
FORC54_RS02480	COG0513	Belongs to the DEAD box helicase family
FORC54_RS02500	COG4974	Belongs to the 'phage' integrase family
FORC54_RS02505	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FORC54_RS02510	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FORC54_RS02520	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FORC54_RS02545	COG3066	DNA modification
FORC54_RS02560	COG0730	response to heat
FORC54_RS02580	COG1283	sodium-dependent phosphate transmembrane transporter activity
FORC54_RS02585	COG0583	DNA-binding transcription factor activity
FORC54_RS02590	COG0640	Transcriptional regulator
FORC54_RS02595	COG0268	Binds directly to 16S ribosomal RNA
FORC54_RS02600	COG0728	peptidoglycan biosynthetic process
FORC54_RS02605	COG0196	riboflavin kinase activity
FORC54_RS02610	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FORC54_RS02615	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FORC54_RS02625	COG1047	Peptidyl-prolyl cis-trans
FORC54_RS02630	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FORC54_RS02640	COG3275	phosphorelay sensor kinase activity
FORC54_RS02645	COG1966	Carbon starvation protein
FORC54_RS02665	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FORC54_RS02680	COG0287	Prephenate dehydrogenase
FORC54_RS02680	COG1605	Chorismate mutase
FORC54_RS02685	COG0739	heme binding
FORC54_RS02695	COG0488	(ABC) transporter
FORC54_RS02705	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
FORC54_RS02710	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
FORC54_RS02715	COG0077	Prephenate dehydratase
FORC54_RS02715	COG1605	Chorismate mutase
FORC54_RS02720	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FORC54_RS02725	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FORC54_RS02740	COG0542	response to heat
FORC54_RS02780	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FORC54_RS02785	COG0826	peptidase U32
FORC54_RS02795	COG0745	RESPONSE REGULATOR receiver
FORC54_RS02800	COG5002	protein histidine kinase activity
FORC54_RS02810	COG0248	Ppx GppA phosphatase
FORC54_RS02815	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FORC54_RS02825	COG0581	inorganic phosphate transmembrane transporter activity
FORC54_RS02830	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FORC54_RS02835	COG0704	Plays a role in the regulation of phosphate uptake
FORC54_RS02850	COG0450	alkyl hydroperoxide reductase
FORC54_RS02855	COG0583	DNA-binding transcription factor activity
FORC54_RS02860	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FORC54_RS02870	COG0517	IMP dehydrogenase activity
FORC54_RS02880	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FORC54_RS02885	COG0343	queuine tRNA-ribosyltransferase activity
FORC54_RS02890	COG1862	Preprotein translocase
FORC54_RS02895	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FORC54_RS02900	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FORC54_RS02915	COG0483	inositol monophosphate 1-phosphatase activity
FORC54_RS02920	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
FORC54_RS02925	COG1959	2 iron, 2 sulfur cluster binding
FORC54_RS02935	COG0822	iron-sulfur transferase activity
FORC54_RS02940	COG0316	Belongs to the HesB IscA family
FORC54_RS02950	COG0443	Heat shock 70 kDa protein
FORC54_RS02955	COG0633	Ferredoxin
FORC54_RS02960	COG2975	iron-sulfur cluster assembly
FORC54_RS02965	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FORC54_RS02970	COG0105	UTP biosynthetic process
FORC54_RS02985	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FORC54_RS02990	COG0124	histidyl-tRNA synthetase
FORC54_RS02995	COG2976	Protein conserved in bacteria
FORC54_RS03000	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FORC54_RS03015	COG2199	diguanylate cyclase activity
FORC54_RS03015	COG2203	Gaf domain
FORC54_RS03025	COG1570	exodeoxyribonuclease VII activity
FORC54_RS03030	COG0517	IMP dehydrogenase activity
FORC54_RS03030	COG0516	GMP reductase activity
FORC54_RS03035	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FORC54_RS03035	COG0519	Catalyzes the synthesis of GMP from XMP
FORC54_RS03045	COG1584	GPR1 FUN34 yaaH family protein
FORC54_RS03050	COG1115	amino acid carrier protein
FORC54_RS03060	COG0583	DNA-binding transcription factor activity
FORC54_RS03080	COG0009	L-threonylcarbamoyladenylate synthase
FORC54_RS03175	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FORC54_RS03180	COG2867	negative regulation of translational initiation
FORC54_RS03185	COG2914	Belongs to the UPF0125 (RnfH) family
FORC54_RS03190	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FORC54_RS03195	COG0497	DNA recombination
FORC54_RS03200	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FORC54_RS03205	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FORC54_RS03220	COG3344	reverse transcriptase
FORC54_RS03245	COG0443	Heat shock 70 kDa protein
FORC54_RS03250	COG0484	heat shock protein binding
FORC54_RS03280	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
FORC54_RS03285	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FORC54_RS03290	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FORC54_RS03295	COG0583	DNA-binding transcription factor activity
FORC54_RS03310	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FORC54_RS03340	COG2195	Cleaves the N-terminal amino acid of tripeptides
FORC54_RS03345	COG2252	PERMEase
FORC54_RS03350	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
FORC54_RS03355	COG1073	alpha beta
FORC54_RS03365	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FORC54_RS03375	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FORC54_RS03380	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FORC54_RS03380	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FORC54_RS03395	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FORC54_RS03400	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FORC54_RS03405	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FORC54_RS03410	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FORC54_RS03420	COG3344	reverse transcriptase
FORC54_RS03430	COG0142	geranyltranstransferase activity
FORC54_RS03435	COG1722	exodeoxyribonuclease VII activity
FORC54_RS03440	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FORC54_RS03455	COG0583	DNA-binding transcription factor activity
FORC54_RS03465	COG2363	Small membrane protein
FORC54_RS03480	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FORC54_RS03485	COG1611	Belongs to the LOG family
FORC54_RS03500	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FORC54_RS03500	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FORC54_RS03510	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
FORC54_RS03515	COG1464	Belongs to the NlpA lipoprotein family
FORC54_RS03520	COG2011	ABC-type metal ion transport system permease component
FORC54_RS03525	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FORC54_RS03530	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FORC54_RS03540	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC54_RS03540	COG1263	PTS System
FORC54_RS03545	COG0366	Alpha amylase catalytic
FORC54_RS03590	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FORC54_RS03600	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FORC54_RS03605	COG0321	lipoyl(octanoyl) transferase activity
FORC54_RS03610	COG2921	Belongs to the UPF0250 family
FORC54_RS03615	COG1686	Belongs to the peptidase S11 family
FORC54_RS03620	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FORC54_RS03625	COG0772	Belongs to the SEDS family
FORC54_RS03630	COG0768	penicillin binding
FORC54_RS03635	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FORC54_RS03640	COG0799	negative regulation of ribosome biogenesis
FORC54_RS03645	COG1466	dna polymerase III delta subunit
FORC54_RS03650	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
FORC54_RS03655	COG0495	leucyl-tRNA aminoacylation
FORC54_RS03660	COG2888	peptidyl-tyrosine sulfation
FORC54_RS03670	COG4535	Mg2 and Co2 transporter CorC
FORC54_RS03675	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FORC54_RS03680	COG1702	phosphate starvation-inducible protein PhoH
FORC54_RS03685	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FORC54_RS03690	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FORC54_RS03700	COG3344	reverse transcriptase
FORC54_RS03790	COG0193	aminoacyl-tRNA hydrolase activity
FORC54_RS03795	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FORC54_RS03800	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FORC54_RS03815	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FORC54_RS03820	COG2890	protein-(glutamine-N5) methyltransferase activity
FORC54_RS03830	COG2912	Transglutaminase-like superfamily
FORC54_RS03835	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FORC54_RS03850	COG1187	pseudouridine synthase activity
FORC54_RS03855	COG2840	Smr protein MutS2
FORC54_RS03870	COG3735	TraB family
FORC54_RS03885	COG2217	Heavy metal translocating P-type atpase
FORC54_RS03885	COG2608	mercury ion transmembrane transporter activity
FORC54_RS03945	COG0835	chemotaxis
FORC54_RS03945	COG0784	Response regulator, receiver
FORC54_RS03950	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FORC54_RS03955	COG1815	bacterial-type flagellum-dependent cell motility
FORC54_RS03970	COG1749	Flagellar hook protein flgE
FORC54_RS03975	COG4787	bacterial-type flagellum-dependent cell motility
FORC54_RS03990	COG1706	bacterial-type flagellum-dependent cell motility
FORC54_RS03995	COG3951	Flagellar rod assembly protein muramidase FlgJ
FORC54_RS03995	COG1705	Flagellar rod assembly protein muramidase FlgJ
FORC54_RS04005	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FORC54_RS04010	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FORC54_RS04015	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FORC54_RS04020	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FORC54_RS04025	COG2190	(PTS) system
FORC54_RS04030	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FORC54_RS04035	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC54_RS04040	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FORC54_RS04045	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
FORC54_RS04075	COG0330	HflC and HflK could
FORC54_RS04080	COG3118	belongs to the thioredoxin family
FORC54_RS04090	COG0300	oxidoreductase activity
FORC54_RS04095	COG1090	epimerase
FORC54_RS04120	COG0622	Phosphoesterase
FORC54_RS04140	COG3710	Transcriptional regulator
FORC54_RS04145	COG0326	Molecular chaperone. Has ATPase activity
FORC54_RS04155	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FORC54_RS04165	COG3104	oligopeptide transport
FORC54_RS04175	COG0367	asparagine synthase
FORC54_RS04180	COG4651	solute:proton antiporter activity
FORC54_RS04180	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FORC54_RS04185	COG1846	Transcriptional regulator
FORC54_RS04185	COG1940	carbohydrate kinase activity
FORC54_RS04190	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FORC54_RS04195	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC54_RS04195	COG1263	PTS System
FORC54_RS04195	COG2190	(PTS) system
FORC54_RS04200	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FORC54_RS04215	COG0716	FMN binding
FORC54_RS04225	COG0596	Alpha beta hydrolase
FORC54_RS04230	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
FORC54_RS04235	COG0033	Phosphoglucomutase
FORC54_RS04240	COG2964	Protein conserved in bacteria
FORC54_RS04245	COG0251	oxidation-reduction process
FORC54_RS04255	COG0446	pyridine nucleotide-disulphide oxidoreductase
FORC54_RS04265	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FORC54_RS04275	COG2009	succinate dehydrogenase
FORC54_RS04280	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FORC54_RS04285	COG1053	succinate dehydrogenase
FORC54_RS04295	COG0567	Dehydrogenase, E1 component
FORC54_RS04300	COG0508	dehydrogenase complex catalyzes the overall conversion of
FORC54_RS04315	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FORC54_RS04320	COG1121	(ABC) transporter
FORC54_RS04325	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
FORC54_RS04335	COG1918	ferrous iron import across plasma membrane
FORC54_RS04340	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FORC54_RS04365	COG3102	Protein conserved in bacteria
FORC54_RS04370	COG0788	formyltetrahydrofolate deformylase activity
FORC54_RS04380	COG1199	ATP-dependent helicase activity
FORC54_RS04385	COG1214	PFAM Peptidase M22, glycoprotease
FORC54_RS04400	COG0596	Alpha beta hydrolase
FORC54_RS04405	COG0318	PFAM AMP-dependent synthetase and ligase
FORC54_RS04410	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FORC54_RS04415	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FORC54_RS04420	COG2894	cell division
FORC54_RS04425	COG0850	regulation of cytokinetic process
FORC54_RS04435	COG2951	lytic endotransglycosylase activity
FORC54_RS04445	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FORC54_RS04460	COG5002	protein histidine kinase activity
FORC54_RS04475	COG1028	Short-chain dehydrogenase reductase Sdr
FORC54_RS04485	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FORC54_RS04510	COG2986	histidine ammonia-lyase
FORC54_RS04515	COG1216	Glycosyl transferase, family 2
FORC54_RS04535	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FORC54_RS04540	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FORC54_RS04605	COG1175	transmembrane transport
FORC54_RS04615	COG3842	ATPase activity
FORC54_RS04625	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FORC54_RS04630	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FORC54_RS04635	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FORC54_RS04645	COG2204	response regulator
FORC54_RS04650	COG4191	Histidine kinase
FORC54_RS04665	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FORC54_RS04670	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FORC54_RS04675	COG0776	regulation of translation
FORC54_RS04680	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FORC54_RS04685	COG1555	photosystem II stabilization
FORC54_RS04695	COG3148	PFAM DTW domain containing protein
FORC54_RS04700	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FORC54_RS04705	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
FORC54_RS04710	COG0436	Aminotransferase
FORC54_RS04715	COG1169	isochorismate synthase
FORC54_RS04725	COG0596	Alpha beta hydrolase
FORC54_RS04730	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FORC54_RS04740	COG0318	PFAM AMP-dependent synthetase and ligase
FORC54_RS04800	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FORC54_RS04815	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FORC54_RS04820	COG1522	sequence-specific DNA binding
FORC54_RS04830	COG1946	Acyl-CoA thioesterase
FORC54_RS04835	COG3126	Type III secretion system lipoprotein chaperone (YscW)
FORC54_RS04870	COG0330	HflC and HflK could
FORC54_RS04910	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FORC54_RS04925	COG3139	Protein of unknown function (DUF1315)
FORC54_RS04930	COG0252	asparaginase activity
FORC54_RS04935	COG0616	signal peptide processing
FORC54_RS04940	COG1902	pentaerythritol trinitrate reductase activity
FORC54_RS04940	COG0446	pyridine nucleotide-disulphide oxidoreductase
FORC54_RS04945	COG0778	Nitroreductase
FORC54_RS04950	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FORC54_RS04955	COG0123	including yeast histone deacetylase and acetoin utilization protein
FORC54_RS04960	COG2205	protein histidine kinase activity
FORC54_RS04960	COG0784	Response regulator, receiver
FORC54_RS04975	COG2731	YhcH YjgK YiaL family protein
FORC54_RS04980	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FORC54_RS04985	COG0569	domain protein
FORC54_RS04995	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FORC54_RS04995	COG0784	Response regulator, receiver
FORC54_RS05020	COG3083	sulfuric ester hydrolase activity
FORC54_RS05025	COG3082	Protein of unknown function (DUF1414)
FORC54_RS05030	COG3081	Nucleoid-associated protein
FORC54_RS05045	COG1757	Na H antiporter
FORC54_RS05050	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FORC54_RS05060	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FORC54_RS05065	COG2095	MarC family integral membrane protein
FORC54_RS05070	COG1012	belongs to the aldehyde dehydrogenase family
FORC54_RS05070	COG1454	alcohol dehydrogenase
FORC54_RS05075	COG1028	Short-chain dehydrogenase reductase Sdr
FORC54_RS05090	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FORC54_RS05100	COG2056	Na+-H+ antiporter family
FORC54_RS05105	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FORC54_RS05110	COG2885	chlorophyll binding
FORC54_RS05120	COG0346	lactoylglutathione lyase activity
FORC54_RS05125	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FORC54_RS05130	COG4660	Part of a membrane complex involved in electron transport
FORC54_RS05135	COG4659	FMN binding
FORC54_RS05140	COG4658	electron transport chain
FORC54_RS05145	COG4656	Part of a membrane complex involved in electron transport
FORC54_RS05150	COG2878	Part of a membrane complex involved in electron transport
FORC54_RS05155	COG4657	Part of a membrane complex involved in electron transport
FORC54_RS05170	COG0556	nucleotide-excision repair
FORC54_RS05175	COG2204	response regulator
FORC54_RS05180	COG2198	Histidine kinase
FORC54_RS05185	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FORC54_RS05195	COG0521	Mo-molybdopterin cofactor biosynthetic process
FORC54_RS05200	COG0315	cyclic pyranopterin monophosphate synthase activity
FORC54_RS05205	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FORC54_RS05210	COG0314	molybdopterin synthase activity
FORC54_RS05225	COG0601	transmembrane transport
FORC54_RS05230	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FORC54_RS05235	COG0444	Belongs to the ABC transporter superfamily
FORC54_RS05245	COG0435	Glutathione S-transferase
FORC54_RS05255	COG2350	Protein conserved in bacteria
FORC54_RS05275	COG1301	dicarboxylic acid transport
FORC54_RS05285	COG0133	tryptophan synthase activity
FORC54_RS05290	COG0134	indole-3-glycerol-phosphate synthase activity
FORC54_RS05290	COG0135	phosphoribosylanthranilate isomerase activity
FORC54_RS05295	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FORC54_RS05300	COG0512	Glutamine amidotransferase of anthranilate synthase
FORC54_RS05305	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FORC54_RS05315	COG0613	PHP domain protein
FORC54_RS05320	COG0009	L-threonylcarbamoyladenylate synthase
FORC54_RS05340	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FORC54_RS05350	COG5001	Diguanylate cyclase
FORC54_RS05355	COG0417	DNA replication proofreading
FORC54_RS05360	COG2197	response regulator
FORC54_RS05365	COG0322	excinuclease ABC activity
FORC54_RS05430	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FORC54_RS05435	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FORC54_RS05440	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FORC54_RS05465	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
FORC54_RS05470	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
FORC54_RS05475	COG0437	4 iron, 4 sulfur cluster binding
FORC54_RS05480	COG3301	Polysulphide reductase, NrfD
FORC54_RS05485	COG1138	Cytochrome C-type biogenesis protein
FORC54_RS05495	COG3088	subunit of a heme lyase
FORC54_RS05495	COG4235	cytochrome complex assembly
FORC54_RS05505	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FORC54_RS05505	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FORC54_RS05510	COG0489	protein tyrosine kinase activity
FORC54_RS05515	COG0572	uridine kinase
FORC54_RS05525	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
FORC54_RS05530	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FORC54_RS05535	COG0659	secondary active sulfate transmembrane transporter activity
FORC54_RS05540	COG1530	ribonuclease E activity
FORC54_RS05550	COG0424	maF-like protein
FORC54_RS05555	COG1399	metal-binding, possibly nucleic acid-binding protein
FORC54_RS05560	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FORC54_RS05565	COG0416	fatty acid biosynthetic process
FORC54_RS05570	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FORC54_RS05585	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FORC54_RS05600	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FORC54_RS05605	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FORC54_RS05615	COG0084	hydrolase, TatD family'
FORC54_RS05620	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC54_RS05620	COG1263	PTS System
FORC54_RS05630	COG0733	neurotransmitter:sodium symporter activity
FORC54_RS05645	COG4667	esterase of the alpha-beta hydrolase superfamily
FORC54_RS05650	COG0469	pyruvate kinase activity
FORC54_RS05655	COG1940	carbohydrate kinase activity
FORC54_RS05660	COG0784	Response regulator, receiver
FORC54_RS05660	COG0835	chemotaxis
FORC54_RS05665	COG0587	DNA-directed DNA polymerase activity
FORC54_RS05680	COG1028	Short-chain dehydrogenase reductase Sdr
FORC54_RS05685	COG0616	signal peptide processing
FORC54_RS05695	COG0539	negative regulation of cytoplasmic translation
FORC54_RS05705	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
FORC54_RS05710	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
FORC54_RS05715	COG0284	orotidine-5'-phosphate decarboxylase activity
FORC54_RS05720	COG4174	ABC transporter (Permease)
FORC54_RS05725	COG4239	(ABC) transporter, permease
FORC54_RS05730	COG4166	transmembrane transport
FORC54_RS05735	COG0444	Belongs to the ABC transporter superfamily
FORC54_RS05740	COG4608	Belongs to the ABC transporter superfamily
FORC54_RS05765	COG0583	DNA-binding transcription factor activity
FORC54_RS05775	COG0686	Belongs to the AlaDH PNT family
FORC54_RS05790	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FORC54_RS05795	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FORC54_RS05810	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FORC54_RS05825	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FORC54_RS05830	COG0501	Belongs to the peptidase M48B family
FORC54_RS05840	COG1028	Short-chain dehydrogenase reductase Sdr
FORC54_RS05855	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FORC54_RS05875	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FORC54_RS05880	COG2915	High frequency lysogenization protein hflD homolog
FORC54_RS05885	COG0482	sulfurtransferase activity
FORC54_RS05895	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FORC54_RS05900	COG2916	Histone family protein nucleoid-structuring protein H-NS
FORC54_RS05905	COG1757	Na H antiporter
FORC54_RS05910	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FORC54_RS05915	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FORC54_RS05920	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FORC54_RS05925	COG0131	Imidazoleglycerol-phosphate dehydratase
FORC54_RS05925	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FORC54_RS05930	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FORC54_RS05935	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FORC54_RS05950	COG3012	SEC-C Motif Domain Protein
FORC54_RS05955	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FORC54_RS05960	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FORC54_RS05965	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FORC54_RS05975	COG1435	thymidine kinase activity
FORC54_RS05985	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FORC54_RS05990	COG0583	DNA-binding transcription factor activity
FORC54_RS06015	COG2116	formate transmembrane transporter activity
FORC54_RS06020	COG0390	transport system, permease component
FORC54_RS06025	COG4459	periplasmic nitrate reductase
FORC54_RS06030	COG3005	denitrification pathway
FORC54_RS06035	COG0243	molybdopterin cofactor binding
FORC54_RS06065	COG1227	inorganic diphosphatase activity
FORC54_RS06080	COG4172	Belongs to the ABC transporter superfamily
FORC54_RS06105	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
FORC54_RS06110	COG1842	Phage shock protein A
FORC54_RS06120	COG1983	PspC domain protein
FORC54_RS06140	COG2818	Glycosylase
FORC54_RS06145	COG0626	cystathionine gamma-synthase activity
FORC54_RS06155	COG0733	neurotransmitter:sodium symporter activity
FORC54_RS06165	COG0564	pseudouridine synthase activity
FORC54_RS06175	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FORC54_RS06180	COG1151	hydroxylamine reductase activity
FORC54_RS06185	COG3604	Transcriptional regulator
FORC54_RS06190	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FORC54_RS06195	COG4136	ATPase activity
FORC54_RS06200	COG4135	transport system, permease component
FORC54_RS06205	COG4134	Bacterial extracellular solute-binding protein
FORC54_RS06215	COG3313	Fe-S protein
FORC54_RS06260	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FORC54_RS06265	COG2205	protein histidine kinase activity
FORC54_RS06280	COG1061	Type III restriction enzyme res subunit
FORC54_RS06290	COG2814	Major facilitator Superfamily
FORC54_RS06300	COG0702	epimerase
FORC54_RS06305	COG1136	(ABC) transporter
FORC54_RS06320	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FORC54_RS06335	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FORC54_RS06340	COG2985	domain, Protein
FORC54_RS06340	COG3273	potassium ion transport
FORC54_RS06345	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FORC54_RS06350	COG1979	alcohol dehydrogenase
FORC54_RS06360	COG3344	reverse transcriptase
FORC54_RS06365	COG1737	Transcriptional regulator
FORC54_RS06370	COG0076	glutamate decarboxylase activity
FORC54_RS06380	COG2431	L-lysine efflux transmembrane transporter activity
FORC54_RS06390	COG3070	regulator of competence-specific genes
FORC54_RS06405	COG5002	protein histidine kinase activity
FORC54_RS06405	COG5002	protein histidine kinase activity
FORC54_RS06420	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FORC54_RS06425	COG4988	ABC transporter
FORC54_RS06430	COG0492	ferredoxin-NADP+ reductase activity
FORC54_RS06440	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FORC54_RS06455	COG0471	metal ion transport
FORC54_RS06460	COG2949	membrane
FORC54_RS06465	COG0281	malic enzyme
FORC54_RS06470	COG1643	Atp-dependent helicase
FORC54_RS06485	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FORC54_RS06495	COG1346	cytolysis
FORC54_RS06500	COG1380	Effector of murein hydrolase LrgA
FORC54_RS06505	COG2925	Exonuclease
FORC54_RS06520	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FORC54_RS06550	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
FORC54_RS06590	COG3063	Type IV pilus biogenesis stability protein PilW
FORC54_RS06595	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FORC54_RS06600	COG0737	Belongs to the 5'-nucleotidase family
FORC54_RS06605	COG2195	Cleaves the N-terminal amino acid of tripeptides
FORC54_RS06615	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
FORC54_RS06625	COG0625	glutathione transferase activity
FORC54_RS06665	COG1278	Cold shock
FORC54_RS06675	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FORC54_RS06680	COG0584	glycerophosphoryl diester phosphodiesterase
FORC54_RS06685	COG1349	DNA-binding transcription factor activity
FORC54_RS06690	COG3842	ATPase activity
FORC54_RS06695	COG0395	ABC-type sugar transport system, permease component
FORC54_RS06700	COG1175	transmembrane transport
FORC54_RS06720	COG0730	response to heat
FORC54_RS06730	COG2197	response regulator
FORC54_RS06770	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FORC54_RS06780	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FORC54_RS06785	COG0372	Belongs to the citrate synthase family
FORC54_RS06790	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FORC54_RS06795	COG2828	Protein conserved in bacteria
FORC54_RS06825	COG0561	phosphatase activity
FORC54_RS06830	COG0602	queuosine metabolic process
FORC54_RS06835	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FORC54_RS06840	COG3706	GGDEF domain
FORC54_RS06865	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FORC54_RS06880	COG2920	part of a sulfur-relay system
FORC54_RS06885	COG0670	Belongs to the BI1 family
FORC54_RS06890	COG1126	abc transporter atp-binding protein
FORC54_RS06895	COG0765	amino acid transport
FORC54_RS06900	COG4597	amino acid ABC transporter
FORC54_RS06905	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC54_RS06915	COG0437	4 iron, 4 sulfur cluster binding
FORC54_RS06920	COG0348	domain, Protein
FORC54_RS06925	COG0204	Acyl-transferase
FORC54_RS06985	COG1846	Transcriptional regulator
FORC54_RS07005	COG3971	2-oxopent-4-enoate hydratase activity
FORC54_RS07040	COG3384	dioxygenase
FORC54_RS07045	COG1012	belongs to the aldehyde dehydrogenase family
FORC54_RS07055	COG1960	acyl-CoA dehydrogenase activity
FORC54_RS07060	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
FORC54_RS07075	COG1115	amino acid carrier protein
FORC54_RS07100	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FORC54_RS07115	COG3290	protein histidine kinase activity
FORC54_RS07120	COG4565	transcriptional regulatory protein
FORC54_RS07125	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FORC54_RS07130	COG0363	glucosamine-6-phosphate deaminase activity
FORC54_RS07135	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FORC54_RS07170	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FORC54_RS07180	COG0438	transferase activity, transferring glycosyl groups
FORC54_RS07215	COG0438	transferase activity, transferring glycosyl groups
FORC54_RS07225	COG2204	response regulator
FORC54_RS07255	COG1366	Belongs to the anti-sigma-factor antagonist family
FORC54_RS07260	COG1793	dna ligase
FORC54_RS07265	COG3706	GGDEF domain
FORC54_RS07275	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FORC54_RS07290	COG2996	Protein conserved in bacteria
FORC54_RS07295	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
FORC54_RS07295	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FORC54_RS07300	COG3008	intermembrane lipid transfer
FORC54_RS07305	COG2995	paraquat-inducible protein a
FORC54_RS07310	COG1132	(ABC) transporter
FORC54_RS07315	COG1956	GAF domain-containing protein
FORC54_RS07320	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
FORC54_RS07335	COG0308	aminopeptidase N
FORC54_RS07345	COG2902	Dehydrogenase
FORC54_RS07360	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FORC54_RS07360	COG0116	Belongs to the methyltransferase superfamily
FORC54_RS07370	COG0488	(ABC) transporter
FORC54_RS07385	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FORC54_RS07390	COG1067	ATP-dependent peptidase activity
FORC54_RS07395	COG3120	sequence-specific DNA binding
FORC54_RS07420	COG2801	Transposase and inactivated derivatives
FORC54_RS07475	COG0784	Response regulator, receiver
FORC54_RS07475	COG2205	protein histidine kinase activity
FORC54_RS07490	COG3278	Belongs to the heme-copper respiratory oxidase family
FORC54_RS07505	COG2010	Cytochrome c
FORC54_RS07515	COG2217	Heavy metal translocating P-type atpase
FORC54_RS07530	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FORC54_RS07535	COG0589	response to stress
FORC54_RS07550	COG2992	FlgJ-related protein
FORC54_RS07560	COG3842	ATPase activity
FORC54_RS07565	COG1176	ABC-type spermidine putrescine transport system, permease component I
FORC54_RS07570	COG1177	transmembrane transport
FORC54_RS07580	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FORC54_RS07585	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FORC54_RS07590	COG0004	ammonium transporteR
FORC54_RS07615	COG0437	4 iron, 4 sulfur cluster binding
FORC54_RS07620	COG3383	formate dehydrogenase (NAD+) activity
FORC54_RS07620	COG0243	molybdopterin cofactor binding
FORC54_RS07650	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FORC54_RS07660	COG0488	(ABC) transporter
FORC54_RS07675	COG3852	Histidine kinase
FORC54_RS07680	COG2204	response regulator
FORC54_RS07690	COG4662	Binding-protein-dependent transport system inner membrane component
FORC54_RS07695	COG3842	ATPase activity
FORC54_RS07700	COG0746	molybdenum cofactor guanylyltransferase activity
FORC54_RS07715	COG1940	carbohydrate kinase activity
FORC54_RS07720	COG3148	PFAM DTW domain containing protein
FORC54_RS07730	COG0840	transmembrane signaling receptor activity
FORC54_RS07735	COG0791	NLP P60 protein
FORC54_RS07745	COG3706	GGDEF domain
FORC54_RS07765	COG0307	riboflavin synthase, alpha
FORC54_RS07770	COG0534	Mate efflux family protein
FORC54_RS07910	COG2801	Transposase and inactivated derivatives
FORC54_RS08485	COG0456	acetyltransferase
FORC54_RS08525	COG0456	acetyltransferase
FORC54_RS08525	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FORC54_RS08580	COG4628	conserved protein (DUF2132)
FORC54_RS08645	COG4115	mRNA cleavage
FORC54_RS08650	COG2161	toxin-antitoxin pair type II binding
FORC54_RS08825	COG1028	Short-chain dehydrogenase reductase Sdr
FORC54_RS08920	COG0384	phenazine biosynthesis protein PhzF
FORC54_RS09500	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC54_RS09520	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC54_RS09785	COG4628	conserved protein (DUF2132)
FORC54_RS09980	COG4628	conserved protein (DUF2132)
FORC54_RS10100	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FORC54_RS10120	COG4326	sporulation control protein
FORC54_RS10130	COG1228	amidohydrolase
FORC54_RS10140	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FORC54_RS10145	COG2986	histidine ammonia-lyase
FORC54_RS10155	COG5640	endopeptidase activity
FORC54_RS10160	COG2020	methyltransferase activity
FORC54_RS10165	COG0247	lactate metabolic process
FORC54_RS10165	COG0277	FAD linked oxidase domain protein
FORC54_RS10180	COG2885	chlorophyll binding
FORC54_RS10195	COG0295	cytidine deaminase activity
FORC54_RS10200	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
FORC54_RS10205	COG0500	methyltransferase
FORC54_RS10215	COG0776	regulation of translation
FORC54_RS10240	COG0072	phenylalanine-tRNA ligase activity
FORC54_RS10240	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FORC54_RS10245	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FORC54_RS10310	COG1166	arginine decarboxylase activity
FORC54_RS10315	COG0010	Belongs to the arginase family
FORC54_RS10320	COG2814	Major facilitator Superfamily
FORC54_RS10325	COG5380	lipid catabolic process
FORC54_RS10330	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
FORC54_RS10355	COG1643	Atp-dependent helicase
FORC54_RS10370	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FORC54_RS10410	COG2894	cell division
FORC54_RS10420	COG4964	Belongs to the GSP D family
FORC54_RS10470	COG3706	GGDEF domain
FORC54_RS10480	COG0443	Heat shock 70 kDa protein
FORC54_RS10485	COG0443	Heat shock 70 kDa protein
FORC54_RS10525	COG2165	general secretion pathway protein
FORC54_RS10540	COG0297	glycogen (starch) synthase activity
FORC54_RS10540	COG0438	transferase activity, transferring glycosyl groups
FORC54_RS10545	COG0438	transferase activity, transferring glycosyl groups
FORC54_RS10570	COG1596	polysaccharide export
FORC54_RS10580	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FORC54_RS10585	COG1115	amino acid carrier protein
FORC54_RS10590	COG1132	(ABC) transporter
FORC54_RS10595	COG1132	(ABC) transporter
FORC54_RS10610	COG0783	Belongs to the Dps family
FORC54_RS10625	COG0814	amino acid
FORC54_RS10630	COG1597	lipid kinase activity
FORC54_RS10640	COG4667	esterase of the alpha-beta hydrolase superfamily
FORC54_RS10650	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FORC54_RS10665	COG0583	DNA-binding transcription factor activity
FORC54_RS10670	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FORC54_RS10675	COG1328	CTP reductase activity
FORC54_RS10680	COG3300	MHYT domain
FORC54_RS10680	COG5001	Diguanylate cyclase
FORC54_RS10695	COG2199	diguanylate cyclase activity
FORC54_RS10695	COG2200	EAL domain
FORC54_RS10700	COG3706	GGDEF domain
FORC54_RS10710	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC54_RS10710	COG4191	Histidine kinase
FORC54_RS10715	COG0471	metal ion transport
FORC54_RS10730	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC54_RS10735	COG3283	Transcriptional regulator of aromatic amino acids metabolism
FORC54_RS10740	COG3768	UPF0283 membrane protein
FORC54_RS10745	COG3106	COG3106 Predicted ATPase
FORC54_RS10765	COG0784	Response regulator, receiver
FORC54_RS10765	COG2205	protein histidine kinase activity
FORC54_RS10775	COG0494	nUDIX hydrolase
FORC54_RS10780	COG0814	amino acid
FORC54_RS10785	COG1760	l-serine dehydratase
FORC54_RS10790	COG2200	EAL domain
FORC54_RS10800	COG0720	synthase
FORC54_RS10810	COG0017	Asparaginyl-tRNA synthetase
FORC54_RS10825	COG2770	Histidine kinase
FORC54_RS10825	COG3437	response regulator, receiver
FORC54_RS10830	COG1448	Aminotransferase
FORC54_RS10850	COG0840	transmembrane signaling receptor activity
FORC54_RS10855	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FORC54_RS10860	COG1846	Transcriptional regulator
FORC54_RS10885	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FORC54_RS10900	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FORC54_RS10905	COG3108	Peptidase M15
FORC54_RS10910	COG2989	Protein conserved in bacteria
FORC54_RS10940	COG2186	Transcriptional regulator
FORC54_RS10945	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FORC54_RS10955	COG0653	protein targeting
FORC54_RS10970	COG0366	Alpha amylase catalytic
FORC54_RS10980	COG4120	Belongs to the binding-protein-dependent transport system permease family
FORC54_RS10990	COG3092	negative regulation of chromosome organization
FORC54_RS10995	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FORC54_RS11000	COG0280	phosphate acetyltransferase
FORC54_RS11000	COG0857	belongs to the CobB CobQ family
FORC54_RS11010	COG0583	DNA-binding transcription factor activity
FORC54_RS11035	COG1032	radical SAM domain protein
FORC54_RS11055	COG2207	Transcriptional regulator
FORC54_RS11080	COG0861	Integral membrane protein TerC family
FORC54_RS11085	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FORC54_RS11090	COG0840	transmembrane signaling receptor activity
FORC54_RS11095	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FORC54_RS11110	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FORC54_RS11180	COG1715	Restriction endonuclease
FORC54_RS11210	COG2205	protein histidine kinase activity
FORC54_RS11210	COG0784	Response regulator, receiver
FORC54_RS11225	COG0754	glutathionylspermidine amidase activity
FORC54_RS11235	COG3766	membrane
FORC54_RS11245	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FORC54_RS11250	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
FORC54_RS11255	COG2885	chlorophyll binding
FORC54_RS11260	COG0823	Involved in the tonB-independent uptake of proteins
FORC54_RS11275	COG0811	peptide transport
FORC54_RS11280	COG0824	Thioesterase
FORC54_RS11290	COG4890	Cyd operon protein YbgT
FORC54_RS11295	COG1294	oxidase, subunit
FORC54_RS11300	COG1271	oxidase subunit
FORC54_RS11305	COG2255	four-way junction helicase activity
FORC54_RS11310	COG0632	four-way junction helicase activity
FORC54_RS11330	COG4106	trans-aconitate 2-methyltransferase activity
FORC54_RS11335	COG0500	methyltransferase
FORC54_RS11340	COG0189	ligase activity
FORC54_RS11340	COG4067	protein conserved in archaea
FORC54_RS11355	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FORC54_RS11360	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
FORC54_RS11365	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
FORC54_RS11370	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FORC54_RS11375	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FORC54_RS11380	COG0745	RESPONSE REGULATOR receiver
FORC54_RS11390	COG1609	Transcriptional regulator
FORC54_RS11395	COG3070	regulator of competence-specific genes
FORC54_RS11420	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FORC54_RS11430	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FORC54_RS11440	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FORC54_RS11455	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FORC54_RS11460	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FORC54_RS11465	COG0542	response to heat
FORC54_RS11470	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FORC54_RS11475	COG1278	Cold shock
FORC54_RS11495	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FORC54_RS11500	COG1199	ATP-dependent helicase activity
FORC54_RS11510	COG3923	Primosomal replication protein n
FORC54_RS11520	COG0840	transmembrane signaling receptor activity
FORC54_RS11565	COG1882	Formate acetyltransferase
FORC54_RS11580	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FORC54_RS11590	COG3013	Belongs to the UPF0304 family
FORC54_RS11595	COG2766	serine protein kinase
FORC54_RS11600	COG2718	Belongs to the UPF0229 family
FORC54_RS11605	COG2719	SpoVR family
FORC54_RS11610	COG2199	diguanylate cyclase activity
FORC54_RS11615	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FORC54_RS11620	COG2835	tetraacyldisaccharide 4'-kinase activity
FORC54_RS11625	COG1663	tetraacyldisaccharide 4'-kinase activity
FORC54_RS11635	COG2333	competence protein COMEC
FORC54_RS11635	COG0658	competence protein
FORC54_RS11645	COG4591	ABC-type transport system involved in lipoprotein release permease component
FORC54_RS11650	COG1136	(ABC) transporter
FORC54_RS11655	COG4591	ABC-type transport system involved in lipoprotein release permease component
FORC54_RS11665	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FORC54_RS11680	COG1252	NADH dehydrogenase
FORC54_RS11710	COG0537	adenosine 5'-monophosphoramidase activity
FORC54_RS11735	COG0617	tRNA 3'-terminal CCA addition
FORC54_RS11735	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FORC54_RS11735	COG0517	IMP dehydrogenase activity
FORC54_RS11740	COG3706	GGDEF domain
FORC54_RS11745	COG1982	Orn Lys Arg decarboxylase major
FORC54_RS11750	COG0531	amino acid
FORC54_RS11760	COG3710	Transcriptional regulator
FORC54_RS11770	COG2239	Acts as a magnesium transporter
FORC54_RS11780	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FORC54_RS11785	COG2226	methyltransferase
FORC54_RS11800	COG1785	Belongs to the alkaline phosphatase family
FORC54_RS11810	COG0346	lactoylglutathione lyase activity
FORC54_RS11820	COG2983	Belongs to the UPF0260 family
FORC54_RS11835	COG0745	RESPONSE REGULATOR receiver
FORC54_RS11840	COG2205	protein histidine kinase activity
FORC54_RS11855	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FORC54_RS11860	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FORC54_RS11870	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FORC54_RS11875	COG2832	Protein of unknown function (DUF454)
FORC54_RS11885	COG0745	RESPONSE REGULATOR receiver
FORC54_RS11890	COG0583	DNA-binding transcription factor activity
FORC54_RS11895	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FORC54_RS11900	COG1286	toxin biosynthetic process
FORC54_RS11905	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
FORC54_RS11910	COG0285	dihydrofolate synthase activity
FORC54_RS11915	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FORC54_RS11920	COG0101	tRNA pseudouridine synthase activity
FORC54_RS11930	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FORC54_RS11940	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FORC54_RS11955	COG3101	peptidyl-lysine hydroxylation
FORC54_RS11960	COG2860	membrane
FORC54_RS11970	COG2890	protein-(glutamine-N5) methyltransferase activity
FORC54_RS11975	COG2840	Smr protein MutS2
FORC54_RS11980	COG2062	phosphohistidine phosphatase, SixA
FORC54_RS11990	COG1025	Belongs to the peptidase M16 family
FORC54_RS12015	COG2067	long-chain fatty acid transport protein
FORC54_RS12020	COG2067	long-chain fatty acid transport protein
FORC54_RS12025	COG2853	Lipoprotein
FORC54_RS12035	COG4235	cytochrome complex assembly
FORC54_RS12035	COG3088	subunit of a heme lyase
FORC54_RS12040	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FORC54_RS12045	COG1138	Cytochrome C-type biogenesis protein
FORC54_RS12050	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
FORC54_RS12055	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FORC54_RS12060	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FORC54_RS12065	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FORC54_RS12070	COG4133	protoheme IX ABC transporter activity
FORC54_RS12080	COG0835	chemotaxis
FORC54_RS12090	COG1192	Involved in chromosome partitioning
FORC54_RS12100	COG0643	Histidine kinase
FORC54_RS12100	COG2198	Histidine kinase
FORC54_RS12100	COG0784	Response regulator, receiver
FORC54_RS12105	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
FORC54_RS12140	COG1684	flagellar biosynthetic protein fliR
FORC54_RS12145	COG1987	bacterial-type flagellum assembly
FORC54_RS12195	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FORC54_RS12205	COG1677	Flagellar hook-basal body complex protein FliE
FORC54_RS12225	COG1516	flagellar protein fliS
FORC54_RS12235	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FORC54_RS12240	COG1334	flagellar protein FlaG
FORC54_RS12245	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FORC54_RS12250	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FORC54_RS12255	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FORC54_RS12260	COG2837	iron assimilation
FORC54_RS12285	COG1393	Belongs to the ArsC family
FORC54_RS12305	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
FORC54_RS12310	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FORC54_RS12315	COG2716	regulation of RNA biosynthetic process
FORC54_RS12320	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FORC54_RS12335	COG4783	chaperone-mediated protein folding
FORC54_RS12340	COG1393	Belongs to the ArsC family
FORC54_RS12360	COG2233	PERMEase
FORC54_RS12365	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FORC54_RS12370	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FORC54_RS12375	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FORC54_RS12380	COG0121	glutamine amidotransferase
FORC54_RS12390	COG1960	acyl-CoA dehydrogenase activity
FORC54_RS12415	COG2249	NAD(P)H dehydrogenase (quinone) activity
FORC54_RS12430	COG0328	RNA-DNA hybrid ribonuclease activity
FORC54_RS12435	COG2226	methyltransferase
FORC54_RS12440	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FORC54_RS12445	COG1388	LysM domain
FORC54_RS12445	COG0741	lytic transglycosylase activity
FORC54_RS12455	COG3021	interspecies interaction between organisms
FORC54_RS12460	COG0347	Belongs to the P(II) protein family
FORC54_RS12475	COG0825	malonyl-CoA metabolic process
FORC54_RS12480	COG0587	DNA-directed DNA polymerase activity
FORC54_RS12485	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FORC54_RS12490	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FORC54_RS12495	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FORC54_RS12500	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FORC54_RS12510	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
FORC54_RS12515	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FORC54_RS12520	COG0750	zinc metalloprotease
FORC54_RS12530	COG0575	Belongs to the CDS family
FORC54_RS12535	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FORC54_RS12540	COG0233	cytoplasmic translational termination
FORC54_RS12545	COG0528	UMP kinase activity
FORC54_RS12550	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FORC54_RS12555	COG0052	Belongs to the universal ribosomal protein uS2 family
FORC54_RS12560	COG0024	Methionine aminopeptidase
FORC54_RS12565	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FORC54_RS12580	COG3098	single-species biofilm formation
FORC54_RS12610	COG1671	Belongs to the UPF0178 family
FORC54_RS12615	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
FORC54_RS12625	COG0254	rRNA binding
FORC54_RS12630	COG1720	tRNA m6t6A37 methyltransferase activity
FORC54_RS12655	COG0733	neurotransmitter:sodium symporter activity
FORC54_RS12670	COG0514	ATP-dependent DNA helicase (RecQ)
FORC54_RS12675	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FORC54_RS12690	COG1477	protein flavinylation
FORC54_RS12695	COG2871	sodium ion transport
FORC54_RS12700	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FORC54_RS12710	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FORC54_RS12715	COG1805	sodium ion transport
FORC54_RS12720	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FORC54_RS12725	COG0271	Belongs to the BolA IbaG family
FORC54_RS12730	COG2813	Specifically methylates the guanine in position
FORC54_RS12745	COG2211	Major facilitator Superfamily
FORC54_RS12755	COG1595	DNA-templated transcription, initiation
FORC54_RS12770	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FORC54_RS12775	COG0693	protein deglycase activity
FORC54_RS12780	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FORC54_RS12790	COG2166	iron-sulfur cluster assembly
FORC54_RS12795	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FORC54_RS12800	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FORC54_RS12820	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FORC54_RS12825	COG1074	ATP-dependent DNA helicase activity
FORC54_RS12830	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FORC54_RS12835	COG3083	sulfuric ester hydrolase activity
FORC54_RS12850	COG3141	response to X-ray
FORC54_RS12855	COG2171	N-acyltransferase activity
FORC54_RS12860	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FORC54_RS12865	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FORC54_RS12870	COG1349	DNA-binding transcription factor activity
FORC54_RS12875	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FORC54_RS12890	COG0189	ligase activity
FORC54_RS12890	COG0569	domain protein
FORC54_RS12905	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FORC54_RS12915	COG0840	transmembrane signaling receptor activity
FORC54_RS12920	COG2017	converts alpha-aldose to the beta-anomer
FORC54_RS12935	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FORC54_RS12940	COG1609	Transcriptional regulator
FORC54_RS12950	COG3250	beta-galactosidase activity
FORC54_RS12955	COG2731	YhcH YjgK YiaL family protein
FORC54_RS12960	COG0531	amino acid
FORC54_RS12965	COG0531	amino acid
FORC54_RS12975	COG3408	Glycogen debranching enzyme
FORC54_RS12975	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
FORC54_RS12990	COG2059	Chromate
FORC54_RS13040	COG4964	Belongs to the GSP D family
FORC54_RS13075	COG1022	Amp-dependent synthetase and ligase
FORC54_RS13080	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FORC54_RS13100	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FORC54_RS13110	COG0560	Phosphoserine phosphatase
FORC54_RS13120	COG0813	purine-nucleoside phosphorylase activity
FORC54_RS13125	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FORC54_RS13130	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FORC54_RS13135	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FORC54_RS13140	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FORC54_RS13145	COG0084	hydrolase, TatD family'
FORC54_RS13155	COG3706	GGDEF domain
FORC54_RS13165	COG0456	acetyltransferase
FORC54_RS13175	COG3153	acetyltransferase
FORC54_RS13180	COG3154	lipid carrier protein
FORC54_RS13190	COG0826	peptidase U32
FORC54_RS13195	COG0826	peptidase U32
FORC54_RS13200	COG0534	Mate efflux family protein
FORC54_RS13215	COG1185	polyribonucleotide nucleotidyltransferase activity
FORC54_RS13235	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FORC54_RS13240	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FORC54_RS13245	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FORC54_RS13255	COG0195	Participates in both transcription termination and antitermination
FORC54_RS13260	COG0779	Required for maturation of 30S ribosomal subunits
FORC54_RS13275	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FORC54_RS13280	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FORC54_RS13285	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FORC54_RS13290	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FORC54_RS13295	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FORC54_RS13300	COG1534	Rna-binding protein
FORC54_RS13325	COG2027	D-alanyl-D-alanine carboxypeptidase
FORC54_RS13330	COG2832	Protein of unknown function (DUF454)
FORC54_RS13335	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FORC54_RS13340	COG0739	heme binding
FORC54_RS13365	COG0628	permease
FORC54_RS13375	COG2205	protein histidine kinase activity
FORC54_RS13375	COG0784	Response regulator, receiver
FORC54_RS13385	COG0601	transmembrane transport
FORC54_RS13390	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FORC54_RS13395	COG0444	Belongs to the ABC transporter superfamily
FORC54_RS13400	COG4608	Belongs to the ABC transporter superfamily
FORC54_RS13410	COG2971	BadF BadG BcrA BcrD
FORC54_RS13425	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FORC54_RS13430	COG3842	ATPase activity
FORC54_RS13440	COG1840	ABC-type Fe3 transport system, periplasmic component
FORC54_RS13445	COG0004	ammonium transporteR
FORC54_RS13450	COG0347	Belongs to the P(II) protein family
FORC54_RS13455	COG3112	Uncharacterised protein family (UPF0231)
FORC54_RS13460	COG3835	regulator
FORC54_RS13465	COG2610	gluconate transmembrane transporter activity
FORC54_RS13470	COG1929	Belongs to the glycerate kinase type-1 family
FORC54_RS13475	COG1049	propionate catabolic process, 2-methylcitrate cycle
FORC54_RS13480	COG1752	Esterase of the alpha-beta hydrolase superfamily
FORC54_RS13485	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FORC54_RS13490	COG1643	Atp-dependent helicase
FORC54_RS13495	COG1489	DNA binding
FORC54_RS13500	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FORC54_RS13505	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FORC54_RS13515	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FORC54_RS13520	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FORC54_RS13530	COG0842	Transport permease protein
FORC54_RS13535	COG1131	(ABC) transporter
FORC54_RS13540	COG0659	secondary active sulfate transmembrane transporter activity
FORC54_RS13545	COG0288	reversible hydration of carbon dioxide
FORC54_RS13560	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FORC54_RS13565	COG0508	dehydrogenase complex catalyzes the overall conversion of
FORC54_RS13570	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FORC54_RS13575	COG2186	Transcriptional regulator
FORC54_RS13580	COG3023	N-Acetylmuramoyl-L-alanine amidase
FORC54_RS13595	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FORC54_RS13600	COG1459	type II secretion system
FORC54_RS13610	COG0237	dephospho-CoA kinase activity
FORC54_RS13620	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FORC54_RS13625	COG0335	large ribosomal subunit rRNA binding
FORC54_RS13630	COG0336	Belongs to the RNA methyltransferase TrmD family
FORC54_RS13635	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FORC54_RS13640	COG0228	four-way junction DNA binding
FORC54_RS13645	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FORC54_RS13650	COG4137	Cytochrome C assembly protein
FORC54_RS13655	COG4536	flavin adenine dinucleotide binding
FORC54_RS13660	COG1854	S-ribosylhomocysteine lyase activity
FORC54_RS13675	COG0612	Peptidase, M16
FORC54_RS13680	COG1238	metal cluster binding
FORC54_RS13690	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
FORC54_RS13695	COG5016	pyruvate
FORC54_RS13695	COG0511	ligase activity, forming carbon-carbon bonds
FORC54_RS13700	COG3630	sodium ion export across plasma membrane
FORC54_RS13745	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
FORC54_RS13750	COG0527	aspartate kinase activity
FORC54_RS13755	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FORC54_RS13765	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FORC54_RS13775	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FORC54_RS13780	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FORC54_RS13785	COG1388	LysM domain
FORC54_RS13785	COG4942	peptidase
FORC54_RS13790	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FORC54_RS13800	COG0585	pseudouridine synthase activity
FORC54_RS13805	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FORC54_RS13815	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
FORC54_RS13830	COG0504	CTP synthase activity
FORC54_RS13835	COG3956	TIGRFAM MazG family protein
FORC54_RS13840	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FORC54_RS13845	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FORC54_RS13850	COG4999	Histidine kinase
FORC54_RS13850	COG3850	Histidine kinase
FORC54_RS13850	COG3437	response regulator, receiver
FORC54_RS13850	COG2205	protein histidine kinase activity
FORC54_RS13870	COG0736	holo-[acyl-carrier-protein] synthase activity
FORC54_RS13875	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FORC54_RS13880	COG1381	Involved in DNA repair and RecF pathway recombination
FORC54_RS13885	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FORC54_RS13900	COG0481	GTPase activity
FORC54_RS13905	COG3086	response to oxidative stress
FORC54_RS13920	COG1595	DNA-templated transcription, initiation
FORC54_RS13925	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FORC54_RS13940	COG0354	folic acid binding
FORC54_RS13955	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FORC54_RS13960	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FORC54_RS13965	COG3079	Belongs to the UPF0149 family
FORC54_RS13970	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
FORC54_RS13980	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FORC54_RS13990	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FORC54_RS14005	COG1279	arginine transmembrane transporter activity
FORC54_RS14010	COG0668	transmembrane transport
FORC54_RS14015	COG0191	fructose-bisphosphate aldolase activity
FORC54_RS14020	COG0126	phosphoglycerate kinase activity
FORC54_RS14025	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FORC54_RS14040	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FORC54_RS14055	COG2356	endonuclease I
FORC54_RS14060	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FORC54_RS14070	COG1678	Uncharacterized ACR, COG1678
FORC54_RS14075	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FORC54_RS14090	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FORC54_RS14095	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FORC54_RS14100	COG0762	integral membrane protein
FORC54_RS14115	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FORC54_RS14120	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FORC54_RS14125	COG2066	Belongs to the glutaminase family
FORC54_RS14130	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FORC54_RS14140	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
FORC54_RS14145	COG0741	lytic transglycosylase activity
FORC54_RS14265	COG1609	Transcriptional regulator
FORC54_RS14270	COG3394	polysaccharide catabolic process
FORC54_RS14275	COG1486	melibiose metabolic process
FORC54_RS14280	COG1447	Phosphotransferase system cellobiose-specific component IIA
FORC54_RS14290	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FORC54_RS14295	COG0726	polysaccharide deacetylase
FORC54_RS14310	COG0795	lipopolysaccharide-transporting ATPase activity
FORC54_RS14315	COG0795	lipopolysaccharide-transporting ATPase activity
FORC54_RS14320	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FORC54_RS14325	COG2927	DNA polymerase III (CHI subunit)
FORC54_RS14330	COG0525	valine-tRNA ligase activity
FORC54_RS14340	COG4269	membrane
FORC54_RS14350	COG0456	acetyltransferase
FORC54_RS14385	COG0251	oxidation-reduction process
FORC54_RS14390	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FORC54_RS14400	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FORC54_RS14405	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FORC54_RS14410	COG0312	modulator of DNA gyrase
FORC54_RS14415	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FORC54_RS14420	COG3164	Protein of unknown function
FORC54_RS14430	COG0424	maF-like protein
FORC54_RS14435	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FORC54_RS14440	COG1792	Involved in formation and maintenance of cell shape
FORC54_RS14445	COG1077	Cell shape determining protein MreB Mrl
FORC54_RS14475	COG2165	general secretion pathway protein
FORC54_RS14480	COG2165	general secretion pathway protein
FORC54_RS14490	COG1459	type II secretion system
FORC54_RS14495	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FORC54_RS14505	COG3409	Peptidoglycan-binding domain 1 protein
FORC54_RS14505	COG3267	Type II secretory pathway component ExeA
FORC54_RS14530	COG2200	EAL domain
FORC54_RS14530	COG2199	diguanylate cyclase activity
FORC54_RS14550	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FORC54_RS14560	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FORC54_RS14570	COG0527	aspartate kinase activity
FORC54_RS14575	COG0646	methionine synthase
FORC54_RS14575	COG1410	methionine synthase
FORC54_RS14670	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FORC54_RS14700	COG0735	belongs to the Fur family
FORC54_RS14715	COG0432	Pfam Uncharacterised protein family UPF0047
FORC54_RS14725	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FORC54_RS14740	COG0359	binds to the 23S rRNA
FORC54_RS14750	COG2965	DNA replication, synthesis of RNA primer
FORC54_RS14755	COG0360	Binds together with S18 to 16S ribosomal RNA
FORC54_RS14760	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FORC54_RS14765	COG0338	D12 class N6 adenine-specific DNA methyltransferase
FORC54_RS14775	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FORC54_RS14780	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FORC54_RS14810	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FORC54_RS14825	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FORC54_RS14825	COG0165	Argininosuccinate lyase
FORC54_RS14830	COG0137	argininosuccinate synthase activity
FORC54_RS14840	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FORC54_RS14845	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FORC54_RS14850	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FORC54_RS14860	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FORC54_RS14865	COG0527	aspartate kinase activity
FORC54_RS14865	COG0460	homoserine dehydrogenase
FORC54_RS14870	COG0626	cystathionine gamma-synthase activity
FORC54_RS14875	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
FORC54_RS14880	COG0281	malic enzyme
FORC54_RS14890	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FORC54_RS14895	COG1609	Transcriptional regulator
FORC54_RS14905	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FORC54_RS14910	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FORC54_RS14915	COG1575	Belongs to the MenA family. Type 1 subfamily
FORC54_RS14925	COG3074	FtsZ-dependent cytokinesis
FORC54_RS14935	COG1494	fructose-1,6-bisphosphatase
FORC54_RS14960	COG0149	triose-phosphate isomerase activity
FORC54_RS14965	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FORC54_RS14975	COG2906	2 iron, 2 sulfur cluster binding
FORC54_RS14985	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FORC54_RS14990	COG0049	tRNA binding
FORC54_RS14995	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FORC54_RS15010	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
FORC54_RS15015	COG2964	Protein conserved in bacteria
FORC54_RS15020	COG0545	Peptidyl-prolyl cis-trans isomerase
FORC54_RS15030	COG2900	Belongs to the SlyX family
FORC54_RS15040	COG1047	Peptidyl-prolyl cis-trans
FORC54_RS15055	COG2249	NAD(P)H dehydrogenase (quinone) activity
FORC54_RS15060	COG0488	(ABC) transporter
FORC54_RS15070	COG0429	hydrolase of the alpha beta-hydrolase fold
FORC54_RS15075	COG3089	Belongs to the UPF0270 family
FORC54_RS15080	COG3954	Phosphoribulokinase
FORC54_RS15085	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FORC54_RS15095	COG1012	belongs to the aldehyde dehydrogenase family
FORC54_RS15105	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FORC54_RS15125	COG0180	Tryptophanyl-tRNA synthetase
FORC54_RS15130	COG0546	phosphoglycolate phosphatase activity
FORC54_RS15135	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FORC54_RS15140	COG0557	exoribonuclease II activity
FORC54_RS15145	COG0402	S-adenosylhomocysteine deaminase activity
FORC54_RS15150	COG1959	2 iron, 2 sulfur cluster binding
FORC54_RS15160	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
FORC54_RS15165	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FORC54_RS15170	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
FORC54_RS15175	COG0330	HflC and HflK could
FORC54_RS15180	COG0330	HflC and HflK could
FORC54_RS15185	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FORC54_RS15190	COG1923	regulation of RNA biosynthetic process
FORC54_RS15200	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FORC54_RS15205	COG0860	N-Acetylmuramoyl-L-alanine amidase
FORC54_RS15210	COG0802	atpase or kinase
FORC54_RS15215	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FORC54_RS15275	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FORC54_RS15280	COG1162	GTPase activity
FORC54_RS15285	COG0688	phosphatidylethanolamine metabolic process
FORC54_RS15290	COG0471	metal ion transport
FORC54_RS15300	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FORC54_RS15310	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FORC54_RS15315	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FORC54_RS15320	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FORC54_RS15325	COG1045	serine acetyltransferase
FORC54_RS15330	COG4942	peptidase
FORC54_RS15350	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
FORC54_RS15355	COG1053	succinate dehydrogenase
FORC54_RS15360	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FORC54_RS15365	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
FORC54_RS15370	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
FORC54_RS15385	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FORC54_RS15390	COG1509	lysine 2,3-aminomutase activity
FORC54_RS15395	COG1285	pathogenesis
FORC54_RS15405	COG0459	protein refolding
FORC54_RS15410	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FORC54_RS15415	COG0534	Mate efflux family protein
FORC54_RS15420	COG0205	6-phosphofructokinase activity
FORC54_RS15430	COG3678	ATP-independent chaperone mediated protein folding
FORC54_RS15435	COG0745	RESPONSE REGULATOR receiver
FORC54_RS15440	COG2205	protein histidine kinase activity
FORC54_RS15445	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FORC54_RS15450	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FORC54_RS15460	COG1027	Aspartate ammonia-lyase
FORC54_RS15465	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FORC54_RS15470	COG4232	protein-disulfide reductase activity
FORC54_RS15480	COG2095	MarC family integral membrane protein
FORC54_RS15490	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FORC54_RS15505	COG0784	Response regulator, receiver
FORC54_RS15505	COG2198	Histidine kinase
FORC54_RS15505	COG2205	protein histidine kinase activity
FORC54_RS15510	COG2814	Major facilitator Superfamily
FORC54_RS15525	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FORC54_RS15530	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FORC54_RS15535	COG0511	ligase activity, forming carbon-carbon bonds
FORC54_RS15540	COG0439	Biotin carboxylase
FORC54_RS15545	COG2264	protein methyltransferase activity
FORC54_RS15555	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FORC54_RS15560	COG0840	transmembrane signaling receptor activity
FORC54_RS15565	COG0789	Transcriptional regulator
FORC54_RS15575	COG0138	bifunctional purine biosynthesis protein purh
FORC54_RS15595	COG1253	flavin adenine dinucleotide binding
FORC54_RS15600	COG3068	Protein conserved in bacteria
FORC54_RS15605	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FORC54_RS15610	COG1573	uracil-dna glycosylase
FORC54_RS15620	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FORC54_RS15640	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
FORC54_RS15645	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FORC54_RS15650	COG0085	RNA polymerase activity
FORC54_RS15655	COG0222	ribosome binding
FORC54_RS15660	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FORC54_RS15665	COG0081	regulation of translation
FORC54_RS15680	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FORC54_RS15685	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FORC54_RS15720	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FORC54_RS15730	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FORC54_RS15815	COG4206	TonB-dependent receptor
FORC54_RS15840	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FORC54_RS15845	COG0328	RNA-DNA hybrid ribonuclease activity
FORC54_RS15855	COG2003	Belongs to the UPF0758 family
FORC54_RS15905	COG0328	RNA-DNA hybrid ribonuclease activity
FORC54_RS15950	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FORC54_RS15960	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FORC54_RS15970	COG2937	Belongs to the GPAT DAPAT family
FORC54_RS15980	COG3161	chorismate lyase activity
FORC54_RS15985	COG1580	Controls the rotational direction of flagella during chemotaxis
FORC54_RS15990	COG0705	Rhomboid family
FORC54_RS15995	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FORC54_RS16005	COG2177	Part of the ABC transporter FtsEX involved in
FORC54_RS16010	COG2884	Cell division ATP-binding protein ftsE
FORC54_RS16015	COG0552	protein localization to endoplasmic reticulum
FORC54_RS16020	COG0742	ribosomal rna small subunit methyltransferase
FORC54_RS16030	COG2095	MarC family integral membrane protein
FORC54_RS16075	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FORC54_RS16080	COG0640	Transcriptional regulator
FORC54_RS16085	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FORC54_RS16090	COG1280	lysine exporter protein (LysE YggA)
FORC54_RS16095	COG2267	carboxylic ester hydrolase activity
FORC54_RS16100	COG0561	phosphatase activity
FORC54_RS16115	COG3148	PFAM DTW domain containing protein
FORC54_RS16120	COG3287	FIST C domain
FORC54_RS16120	COG2199	diguanylate cyclase activity
FORC54_RS16120	COG2200	EAL domain
FORC54_RS16125	COG1011	Hydrolase
FORC54_RS16130	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FORC54_RS16140	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FORC54_RS16145	COG0019	diaminopimelate decarboxylase activity
FORC54_RS16155	COG1965	Belongs to the frataxin family
FORC54_RS16165	COG0181	hydroxymethylbilane synthase activity
FORC54_RS16175	COG2959	enzyme of heme biosynthesis
FORC54_RS16185	COG2081	HI0933 family
FORC54_RS16195	COG1528	Iron-storage protein
FORC54_RS16200	COG0589	response to stress
FORC54_RS16215	COG0742	ribosomal rna small subunit methyltransferase
FORC54_RS16220	COG5002	protein histidine kinase activity
FORC54_RS16220	COG5001	Diguanylate cyclase
FORC54_RS16225	COG1522	sequence-specific DNA binding
FORC54_RS16235	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FORC54_RS16240	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FORC54_RS16245	COG0800	Aldolase
FORC54_RS16250	COG2610	gluconate transmembrane transporter activity
FORC54_RS16255	COG3265	gluconokinase activity
FORC54_RS16260	COG0129	dihydroxy-acid dehydratase activity
FORC54_RS16265	COG1609	Transcriptional regulator
FORC54_RS16270	COG0745	RESPONSE REGULATOR receiver
FORC54_RS16280	COG0515	serine threonine protein kinase
FORC54_RS16280	COG2815	serine threonine protein kinase
FORC54_RS16315	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FORC54_RS16320	COG0601	transmembrane transport
FORC54_RS16325	COG4166	transmembrane transport
FORC54_RS16330	COG4172	Belongs to the ABC transporter superfamily
FORC54_RS16370	COG1309	transcriptional regulator
FORC54_RS16375	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FORC54_RS16380	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FORC54_RS16385	COG2960	long-chain fatty acid transporting porin activity
FORC54_RS16390	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FORC54_RS16440	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FORC54_RS16450	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FORC54_RS16455	COG0408	coproporphyrinogen oxidase activity
FORC54_RS16460	COG0009	L-threonylcarbamoyladenylate synthase
FORC54_RS16465	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FORC54_RS16475	COG0551	DNA topoisomerase type I activity
FORC54_RS16480	COG2922	Belongs to the Smg family
FORC54_RS16485	COG0758	DNA mediated transformation
FORC54_RS16495	COG0242	peptide deformylase activity
FORC54_RS16500	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FORC54_RS16505	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FORC54_RS16505	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FORC54_RS16510	COG0569	domain protein
FORC54_RS16515	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FORC54_RS16520	COG1272	protein, Hemolysin III
FORC54_RS16525	COG4326	sporulation control protein
FORC54_RS16530	COG3084	Protein conserved in bacteria
FORC54_RS16540	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FORC54_RS16545	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FORC54_RS16550	COG0204	Acyl-transferase
FORC54_RS16560	COG0606	chelatase, subunit chli
FORC54_RS16570	COG3978	acetolactate synthase activity
FORC54_RS16575	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FORC54_RS16580	COG0129	dihydroxy-acid dehydratase activity
FORC54_RS16590	COG0583	DNA-binding transcription factor activity
FORC54_RS16595	COG2814	Major facilitator Superfamily
FORC54_RS16605	COG0765	amino acid transport
FORC54_RS16615	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FORC54_RS16620	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FORC54_RS16625	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FORC54_RS16630	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FORC54_RS16635	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FORC54_RS16640	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FORC54_RS16650	COG0356	it plays a direct role in the translocation of protons across the membrane
FORC54_RS16655	COG3312	ion transport
FORC54_RS16660	COG1475	DNA binding
FORC54_RS16665	COG1192	Involved in chromosome partitioning
FORC54_RS16670	COG0357	Ribosomal RNA small subunit methyltransferase G
FORC54_RS16675	COG0445	tRNA wobble uridine modification
FORC54_RS16685	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FORC54_RS16695	COG0706	membrane insertase activity
FORC54_RS16705	COG0594	ribonuclease P activity
FORC54_RS16710	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FORC54_RS16715	COG1126	abc transporter atp-binding protein
FORC54_RS16740	COG4608	Belongs to the ABC transporter superfamily
FORC54_RS16745	COG0444	Belongs to the ABC transporter superfamily
FORC54_RS16755	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FORC54_RS16755	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
FORC54_RS16775	COG0217	transcriptional regulatory protein
FORC54_RS16790	COG1136	(ABC) transporter
FORC54_RS16795	COG4591	ABC-type transport system involved in lipoprotein release permease component
FORC54_RS16810	COG3275	phosphorelay sensor kinase activity
FORC54_RS16835	COG0786	glutamate:sodium symporter activity
FORC54_RS16840	COG0786	glutamate:sodium symporter activity
FORC54_RS16850	COG0363	glucosamine-6-phosphate deaminase activity
FORC54_RS16880	COG3344	reverse transcriptase
FORC54_RS16890	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FORC54_RS16895	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FORC54_RS16900	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FORC54_RS16920	COG1309	transcriptional regulator
FORC54_RS16940	COG3123	guanosine phosphorylase activity
FORC54_RS16950	COG1741	Belongs to the pirin family
FORC54_RS16960	COG5001	Diguanylate cyclase
FORC54_RS16965	COG3706	GGDEF domain
FORC54_RS17030	COG1982	Orn Lys Arg decarboxylase major
FORC54_RS17035	COG0531	amino acid
FORC54_RS17070	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FORC54_RS17075	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
FORC54_RS17080	COG1162	GTPase activity
FORC54_RS17085	COG2847	Copper chaperone PCu(A)C
FORC54_RS17090	COG1999	signal sequence binding
FORC54_RS17115	COG2909	trisaccharide binding
FORC54_RS17120	COG0058	SHG alpha-glucan phosphorylase activity
FORC54_RS17125	COG1640	4-alpha-glucanotransferase
FORC54_RS17130	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FORC54_RS17135	COG0840	transmembrane signaling receptor activity
FORC54_RS17140	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FORC54_RS17165	COG2184	nucleotidyltransferase activity
FORC54_RS17185	COG1012	belongs to the aldehyde dehydrogenase family
FORC54_RS17190	COG0625	glutathione transferase activity
FORC54_RS17195	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FORC54_RS17200	COG1283	sodium-dependent phosphate transmembrane transporter activity
FORC54_RS17205	COG0612	Peptidase, M16
FORC54_RS17215	COG0583	DNA-binding transcription factor activity
FORC54_RS17225	COG0642	Histidine kinase
FORC54_RS17235	COG2199	diguanylate cyclase activity
FORC54_RS17260	COG1609	Transcriptional regulator
FORC54_RS17275	COG0395	ABC-type sugar transport system, permease component
FORC54_RS17280	COG2723	6-phospho-beta-galactosidase activity
FORC54_RS17290	COG1609	Transcriptional regulator
FORC54_RS17300	COG0747	negative chemotaxis
FORC54_RS17310	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FORC54_RS17315	COG0444	Belongs to the ABC transporter superfamily
FORC54_RS17320	COG4608	Belongs to the ABC transporter superfamily
FORC54_RS17330	COG1609	Transcriptional regulator
FORC54_RS17345	COG4580	involved in the transport of maltose and maltodextrins
FORC54_RS17360	COG1472	Belongs to the glycosyl hydrolase 3 family
FORC54_RS17365	COG0534	Mate efflux family protein
FORC54_RS17375	COG1566	PFAM secretion protein HlyD family protein
FORC54_RS17400	COG0564	pseudouridine synthase activity
FORC54_RS17425	COG1609	Transcriptional regulator
FORC54_RS17435	COG1129	ABC transporter
FORC54_RS17460	COG2211	Major facilitator Superfamily
FORC54_RS17465	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FORC54_RS17470	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FORC54_RS17475	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
FORC54_RS17480	COG2188	Transcriptional regulator
FORC54_RS17485	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FORC54_RS17485	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FORC54_RS17485	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC54_RS17490	COG0383	alpha-mannosidase activity
FORC54_RS17495	COG1929	Belongs to the glycerate kinase type-1 family
FORC54_RS17500	COG1482	cell wall glycoprotein biosynthetic process
FORC54_RS17540	COG1482	cell wall glycoprotein biosynthetic process
FORC54_RS17545	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC54_RS17545	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FORC54_RS17545	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FORC54_RS17550	COG2207	Transcriptional regulator
FORC54_RS17560	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FORC54_RS17565	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FORC54_RS17575	COG3537	Alpha-1,2-mannosidase
FORC54_RS17580	COG3537	Alpha-1,2-mannosidase
FORC54_RS17585	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FORC54_RS17590	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FORC54_RS17590	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FORC54_RS17590	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC54_RS17605	COG3383	formate dehydrogenase (NAD+) activity
FORC54_RS17615	COG1609	Transcriptional regulator
FORC54_RS17620	COG1263	PTS System
FORC54_RS17620	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC54_RS17625	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FORC54_RS17630	COG1482	cell wall glycoprotein biosynthetic process
FORC54_RS17635	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FORC54_RS17640	COG0583	DNA-binding transcription factor activity
FORC54_RS17665	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
FORC54_RS17685	COG0583	DNA-binding transcription factor activity
FORC54_RS17700	COG0137	argininosuccinate synthase activity
FORC54_RS17710	COG1301	dicarboxylic acid transport
FORC54_RS17755	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FORC54_RS17760	COG2175	clavaminate synthase activity
FORC54_RS17795	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FORC54_RS17805	COG3706	GGDEF domain
FORC54_RS17820	COG2356	endonuclease I
FORC54_RS17835	COG1368	sulfuric ester hydrolase activity
FORC54_RS17840	COG2194	sulfuric ester hydrolase activity
FORC54_RS17845	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FORC54_RS17850	COG2205	protein histidine kinase activity
FORC54_RS17855	COG0745	RESPONSE REGULATOR receiver
FORC54_RS17875	COG4221	oxidoreductase activity
FORC54_RS17900	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FORC54_RS17905	COG0076	glutamate decarboxylase activity
FORC54_RS17910	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FORC54_RS17920	COG0561	phosphatase activity
FORC54_RS17935	COG0671	phosphoesterase, PA-phosphatase related
FORC54_RS17940	COG0351	phosphomethylpyrimidine kinase
FORC54_RS18010	COG2814	Major facilitator Superfamily
FORC54_RS18025	COG0039	L-malate dehydrogenase activity
FORC54_RS18030	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FORC54_RS18035	COG4771	TonB-dependent receptor
FORC54_RS18055	COG0393	Putative heavy-metal-binding
FORC54_RS18070	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FORC54_RS18080	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FORC54_RS18100	COG0753	catalase activity
FORC54_RS18120	COG0346	lactoylglutathione lyase activity
FORC54_RS18130	COG2211	Major facilitator Superfamily
FORC54_RS18145	COG3240	lipase activity
FORC54_RS18200	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FORC54_RS18210	COG3646	Phage regulatory protein
FORC54_RS18215	COG0582	viral genome integration into host DNA
FORC54_RS18280	COG4626	Terminase
FORC54_RS18280	COG1802	Transcriptional regulator
FORC54_RS18305	COG1403	HNH endonuclease
FORC54_RS18315	COG0037	tRNA processing
FORC54_RS18350	COG3772	lysozyme
FORC54_RS18380	COG1030	water channel activity
FORC54_RS18470	COG1063	alcohol dehydrogenase
FORC54_RS18525	COG3040	lipid binding
FORC54_RS18565	COG3111	PFAM Bacterial OB fold (BOF) protein
FORC54_RS18575	COG2274	protein secretion by the type I secretion system
FORC54_RS18585	COG1538	Outer membrane efflux protein
FORC54_RS18605	COG0668	transmembrane transport
FORC54_RS18630	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC54_RS18635	COG0793	Belongs to the peptidase S41A family
FORC54_RS18635	COG4946	Tricorn protease homolog
FORC54_RS18650	COG1122	ATPase activity
FORC54_RS18655	COG4720	Psort location CytoplasmicMembrane, score
FORC54_RS18660	COG1566	PFAM secretion protein HlyD family protein
FORC54_RS18685	COG0813	purine-nucleoside phosphorylase activity
FORC54_RS18690	COG3272	Protein of unknown function (DUF1722)
FORC54_RS18695	COG0789	Transcriptional regulator
FORC54_RS18700	COG0415	Belongs to the DNA photolyase family
FORC54_RS18705	COG1376	ErfK ybiS ycfS ynhG family protein
FORC54_RS18705	COG1388	LysM domain
FORC54_RS18715	COG0513	Belongs to the DEAD box helicase family
FORC54_RS18755	COG0573	inorganic phosphate transmembrane transporter activity
FORC54_RS18760	COG0581	inorganic phosphate transmembrane transporter activity
FORC54_RS18765	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FORC54_RS18770	COG5001	Diguanylate cyclase
FORC54_RS18770	COG3706	GGDEF domain
FORC54_RS18770	COG4251	negative regulation of phosphorylation
FORC54_RS18770	COG2203	Gaf domain
FORC54_RS18780	COG2304	oxidoreductase activity
FORC54_RS18800	COG0714	Associated with various cellular activities
FORC54_RS18870	COG1596	polysaccharide export
FORC54_RS18880	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FORC54_RS18885	COG3842	ATPase activity
FORC54_RS18900	COG1175	transmembrane transport
FORC54_RS18905	COG3833	ABC-type maltose transport systems, permease component
FORC54_RS18935	COG2354	Protein conserved in bacteria
FORC54_RS18945	COG0418	dihydroorotase activity
FORC54_RS18950	COG3217	Mosc domain protein beta barrel domain protein
FORC54_RS18950	COG0633	Ferredoxin
FORC54_RS18950	COG0633	Ferredoxin
FORC54_RS18950	COG3217	Mosc domain protein beta barrel domain protein
FORC54_RS18955	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FORC54_RS19000	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FORC54_RS19005	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC54_RS19015	COG0848	biopolymer transport protein
FORC54_RS19020	COG0811	peptide transport
FORC54_RS19025	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
FORC54_RS19035	COG3721	Heme iron utilization protein
FORC54_RS19040	COG0748	coenzyme F420 binding
FORC54_RS19050	COG0835	chemotaxis
FORC54_RS19050	COG0784	Response regulator, receiver
FORC54_RS19055	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FORC54_RS19060	COG0589	response to stress
FORC54_RS19065	COG0366	Alpha amylase catalytic
FORC54_RS19075	COG0840	transmembrane signaling receptor activity
FORC54_RS19090	COG3314	Sporulation integral membrane protein YlbJ
FORC54_RS19110	COG0739	heme binding
FORC54_RS19115	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FORC54_RS19130	COG2084	Dehydrogenase
FORC54_RS19155	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FORC54_RS19175	COG0840	transmembrane signaling receptor activity
FORC54_RS19190	COG3706	GGDEF domain
FORC54_RS19195	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FORC54_RS19195	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FORC54_RS19200	COG1765	OsmC-like protein
FORC54_RS19225	COG1011	Hydrolase
FORC54_RS19250	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FORC54_RS19255	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FORC54_RS19255	COG2207	Transcriptional regulator
FORC54_RS19265	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FORC54_RS19270	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FORC54_RS19275	COG1840	ABC-type Fe3 transport system, periplasmic component
FORC54_RS19280	COG3842	ATPase activity
FORC54_RS19305	COG0583	DNA-binding transcription factor activity
FORC54_RS19315	COG3104	oligopeptide transport
FORC54_RS19320	COG1760	l-serine dehydratase
FORC54_RS19340	COG1686	Belongs to the peptidase S11 family
FORC54_RS19360	COG1309	transcriptional regulator
FORC54_RS19365	COG1012	belongs to the aldehyde dehydrogenase family
FORC54_RS19385	COG4175	Glycine betaine
FORC54_RS19390	COG3059	membrane
FORC54_RS19400	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FORC54_RS19420	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FORC54_RS19425	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
FORC54_RS19430	COG0247	lactate metabolic process
FORC54_RS19445	COG1619	proteins homologs of microcin C7 resistance protein MccF
FORC54_RS19450	COG2133	pyrroloquinoline quinone binding
FORC54_RS19460	COG1454	alcohol dehydrogenase
FORC54_RS19465	COG0443	Heat shock 70 kDa protein
FORC54_RS19470	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FORC54_RS19500	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FORC54_RS19505	COG3174	membrane
FORC54_RS19530	COG0814	amino acid
FORC54_RS19535	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FORC54_RS19560	COG2962	Rard protein
FORC54_RS19575	COG0671	phosphoesterase, PA-phosphatase related
FORC54_RS19585	COG1288	antiporter activity
FORC54_RS19600	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
FORC54_RS19615	COG2425	protein containing a von Willebrand factor type A (vWA) domain
FORC54_RS19620	COG2315	Protein conserved in bacteria
FORC54_RS19635	COG1869	D-ribose catabolic process
FORC54_RS19640	COG1129	ABC transporter
FORC54_RS19645	COG1172	Belongs to the binding-protein-dependent transport system permease family
FORC54_RS19650	COG1879	ABC-type sugar transport system periplasmic component
FORC54_RS19655	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FORC54_RS19660	COG1609	Transcriptional regulator
FORC54_RS19670	COG0784	Response regulator, receiver
FORC54_RS19670	COG0835	chemotaxis
FORC54_RS19680	COG0456	acetyltransferase
FORC54_RS19710	COG0420	3'-5' exonuclease activity
FORC54_RS19715	COG0419	ATPase involved in DNA repair
FORC54_RS19725	COG0583	DNA-binding transcription factor activity
FORC54_RS19745	COG4964	Belongs to the GSP D family
FORC54_RS19845	COG0110	maltose O-acetyltransferase activity
FORC54_RS19865	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC54_RS19870	COG4605	iron ion homeostasis
FORC54_RS19875	COG4604	ABC transporter, ATP-binding protein
FORC54_RS19880	COG0789	Transcriptional regulator
FORC54_RS19910	COG1289	transmembrane transporter activity
FORC54_RS19915	COG0210	DNA helicase
FORC54_RS19920	COG1803	Methylglyoxal synthase
FORC54_RS19925	COG1879	ABC-type sugar transport system periplasmic component
FORC54_RS19955	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FORC54_RS19960	COG3005	denitrification pathway
FORC54_RS19985	COG0513	Belongs to the DEAD box helicase family
FORC54_RS19995	COG5001	Diguanylate cyclase
FORC54_RS19995	COG1716	ATPase activity
FORC54_RS20020	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FORC54_RS20035	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
FORC54_RS20040	COG0513	Belongs to the DEAD box helicase family
FORC54_RS20045	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FORC54_RS20050	COG3119	arylsulfatase activity
FORC54_RS20070	COG0714	Associated with various cellular activities
FORC54_RS20105	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
FORC54_RS20115	COG0641	radical SAM
FORC54_RS20145	COG2814	Major facilitator Superfamily
FORC54_RS20190	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FORC54_RS20200	COG1132	(ABC) transporter
FORC54_RS20260	COG0464	growth
FORC54_RS20265	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FORC54_RS20265	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FORC54_RS20270	COG0509	glycine decarboxylation via glycine cleavage system
FORC54_RS20275	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FORC54_RS20320	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
FORC54_RS20320	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FORC54_RS20320	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FORC54_RS20325	COG1105	Belongs to the carbohydrate kinase PfkB family
FORC54_RS20330	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC54_RS20330	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC54_RS20335	COG1609	Transcriptional regulator
FORC54_RS20360	COG0469	pyruvate kinase activity
FORC54_RS20365	COG2271	Major facilitator Superfamily
FORC54_RS20375	COG4191	Histidine kinase
FORC54_RS20385	COG1979	alcohol dehydrogenase
FORC54_RS20390	COG2207	Transcriptional regulator
FORC54_RS20400	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FORC54_RS20405	COG2759	Belongs to the formate--tetrahydrofolate ligase family
FORC54_RS20410	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FORC54_RS20425	COG3437	response regulator, receiver
FORC54_RS20425	COG0784	Response regulator, receiver
FORC54_RS20430	COG0546	phosphoglycolate phosphatase activity
FORC54_RS20450	COG0513	Belongs to the DEAD box helicase family
FORC54_RS20465	COG3038	cytochrome b561
FORC54_RS20470	COG2353	YceI-like domain
FORC54_RS20475	COG2116	formate transmembrane transporter activity
FORC54_RS20480	COG0583	DNA-binding transcription factor activity
FORC54_RS20490	COG3593	DNA synthesis involved in DNA repair
FORC54_RS20495	COG0737	Belongs to the 5'-nucleotidase family
FORC54_RS20500	COG0861	Integral membrane protein TerC family
FORC54_RS20530	COG2267	carboxylic ester hydrolase activity
FORC54_RS20535	COG2067	long-chain fatty acid transport protein
FORC54_RS20550	COG2050	protein possibly involved in aromatic compounds catabolism
FORC54_RS20560	COG4533	DNA binding
FORC54_RS20570	COG0366	Alpha amylase catalytic
FORC54_RS20575	COG0583	DNA-binding transcription factor activity
FORC54_RS20595	COG0484	heat shock protein binding
FORC54_RS20610	COG5001	Diguanylate cyclase
FORC54_RS20610	COG1716	ATPase activity
FORC54_RS20615	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FORC54_RS20625	COG4181	ATPase activity
FORC54_RS20630	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FORC54_RS20635	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FORC54_RS20635	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FORC54_RS20640	COG1984	allophanate hydrolase subunit 2
FORC54_RS20645	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FORC54_RS20650	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FORC54_RS20660	COG5002	protein histidine kinase activity
FORC54_RS20660	COG5001	Diguanylate cyclase
FORC54_RS20660	COG3447	MASE1 domain protein
FORC54_RS20670	COG0583	DNA-binding transcription factor activity
FORC54_RS20675	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC54_RS20675	COG0045	succinate-CoA ligase (ADP-forming) activity
FORC54_RS20675	COG1042	CoA-binding domain protein
FORC54_RS20685	COG1181	Belongs to the D-alanine--D-alanine ligase family
FORC54_RS20695	COG0023	Translation Initiation Factor
FORC54_RS20700	COG2801	Transposase and inactivated derivatives
FORC54_RS20715	COG3140	Belongs to the UPF0181 family
FORC54_RS20730	COG0745	RESPONSE REGULATOR receiver
FORC54_RS20740	COG3344	reverse transcriptase
FORC54_RS20750	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FORC54_RS20755	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FORC54_RS20770	COG3706	GGDEF domain
FORC54_RS20780	COG2199	diguanylate cyclase activity
FORC54_RS20790	COG1846	Transcriptional regulator
FORC54_RS20795	COG0697	spore germination
FORC54_RS20805	COG4149	molybdate abc transporter
FORC54_RS20810	COG0725	ABC transporter, periplasmic molybdate-binding protein
FORC54_RS20830	COG0189	ligase activity
FORC54_RS20830	COG4067	protein conserved in archaea
FORC54_RS20840	COG0602	queuosine metabolic process
FORC54_RS20845	COG1328	CTP reductase activity
FORC54_RS20900	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FORC54_RS20905	COG3118	belongs to the thioredoxin family
FORC54_RS20920	COG0534	Mate efflux family protein
FORC54_RS20940	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FORC54_RS20955	COG0848	biopolymer transport protein
FORC54_RS20960	COG0811	peptide transport
FORC54_RS20965	COG0811	peptide transport
FORC54_RS21000	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FORC54_RS21005	COG0840	transmembrane signaling receptor activity
FORC54_RS21025	COG3344	reverse transcriptase
FORC54_RS21045	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FORC54_RS21055	COG3706	GGDEF domain
FORC54_RS21055	COG4251	negative regulation of phosphorylation
FORC54_RS21055	COG5001	Diguanylate cyclase
FORC54_RS21055	COG2203	Gaf domain
FORC54_RS21065	COG0010	Belongs to the arginase family
FORC54_RS21070	COG0513	Belongs to the DEAD box helicase family
FORC54_RS21085	COG0523	cobalamin synthesis protein
FORC54_RS21110	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FORC54_RS21110	COG2146	nitrite reductase [NAD(P)H] activity
FORC54_RS21115	COG1116	anion transmembrane transporter activity
FORC54_RS21120	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FORC54_RS21125	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FORC54_RS21125	COG1116	anion transmembrane transporter activity
FORC54_RS21135	COG3707	response regulator
FORC54_RS21155	COG0243	molybdopterin cofactor binding
FORC54_RS21165	COG0366	Alpha amylase catalytic
FORC54_RS21170	COG0840	transmembrane signaling receptor activity
FORC54_RS21175	COG0840	transmembrane signaling receptor activity
FORC54_RS21190	COG2271	Major facilitator Superfamily
FORC54_RS21195	COG0584	glycerophosphoryl diester phosphodiesterase
FORC54_RS21200	COG0312	modulator of DNA gyrase
FORC54_RS21205	COG0312	modulator of DNA gyrase
FORC54_RS21215	COG3069	C4-dicarboxylate transmembrane transporter activity
FORC54_RS21220	COG1704	LemA family
FORC54_RS21225	COG0501	Belongs to the peptidase M48B family
FORC54_RS21330	COG0631	protein serine/threonine phosphatase activity
FORC54_RS21365	COG2815	serine threonine protein kinase
FORC54_RS21365	COG0515	serine threonine protein kinase
FORC54_RS21385	COG3530	Putative quorum-sensing-regulated virulence factor
FORC54_RS21405	COG2154	pterin-4-alpha-carbinolamine dehydratase
FORC54_RS21410	COG3186	Phenylalanine-4-hydroxylase
FORC54_RS21415	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FORC54_RS21440	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
FORC54_RS21450	COG4191	Histidine kinase
FORC54_RS21450	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC54_RS21455	COG0784	Response regulator, receiver
FORC54_RS21455	COG3437	response regulator, receiver
FORC54_RS21510	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
FORC54_RS21510	COG3064	Membrane
FORC54_RS21510	COG1073	alpha beta
FORC54_RS21515	COG2994	toxin metabolic process
FORC54_RS21550	COG5642	Protein of unknown function (DUF2384)
FORC54_RS21560	COG1028	Short-chain dehydrogenase reductase Sdr
FORC54_RS21570	COG1024	Enoyl-CoA hydratase
FORC54_RS21575	COG1024	Enoyl-CoA hydratase
FORC54_RS21590	COG0183	Belongs to the thiolase family
FORC54_RS21600	COG1960	acyl-CoA dehydrogenase activity
FORC54_RS21605	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FORC54_RS21610	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FORC54_RS21630	COG1278	Cold shock
FORC54_RS21645	COG1309	transcriptional regulator
FORC54_RS21650	COG2130	NADP-dependent
FORC54_RS21670	COG2197	response regulator
FORC54_RS21675	COG3851	Histidine kinase
FORC54_RS21680	COG2271	Major facilitator Superfamily
FORC54_RS21685	COG1482	cell wall glycoprotein biosynthetic process
FORC54_RS21695	COG5001	Diguanylate cyclase
FORC54_RS21705	COG3036	rescue of stalled ribosome
FORC54_RS21710	COG1278	Cold shock
FORC54_RS21740	COG0545	Peptidyl-prolyl cis-trans isomerase
FORC54_RS21745	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FORC54_RS21750	COG0840	transmembrane signaling receptor activity
FORC54_RS21770	COG2195	Cleaves the N-terminal amino acid of tripeptides
FORC54_RS21780	COG4989	oxidoreductase activity
FORC54_RS21795	COG0038	chloride channel
FORC54_RS21805	COG0302	gtp cyclohydrolase
FORC54_RS21810	COG0303	'Molybdopterin
FORC54_RS21815	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FORC54_RS21825	COG2897	thiosulfate sulfurtransferase activity
FORC54_RS21845	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FORC54_RS21865	COG0840	transmembrane signaling receptor activity
FORC54_RS21870	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FORC54_RS21880	COG0109	protoheme IX farnesyltransferase activity
FORC54_RS21885	COG1612	heme a metabolic process
FORC54_RS21910	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
FORC54_RS21915	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FORC54_RS21920	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FORC54_RS21925	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FORC54_RS21935	COG1280	lysine exporter protein (LysE YggA)
FORC54_RS21960	COG1846	Transcriptional regulator
FORC54_RS21965	COG1764	response to oxidative stress
FORC54_RS21975	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FORC54_RS21990	COG0697	spore germination
FORC54_RS22005	COG2814	Major facilitator Superfamily
FORC54_RS22010	COG0583	DNA-binding transcription factor activity
FORC54_RS22015	COG4251	negative regulation of phosphorylation
FORC54_RS22015	COG5001	Diguanylate cyclase
FORC54_RS22015	COG3706	GGDEF domain
FORC54_RS22015	COG2203	Gaf domain
FORC54_RS22020	COG0251	oxidation-reduction process
FORC54_RS22045	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
FORC54_RS22055	COG1737	Transcriptional regulator
FORC54_RS22055	COG0837	glucose binding
FORC54_RS22065	COG1131	(ABC) transporter
FORC54_RS22070	COG0842	Transport permease protein
FORC54_RS22090	COG1846	Transcriptional regulator
FORC54_RS22110	COG0513	Belongs to the DEAD box helicase family
FORC54_RS22135	COG3568	Endonuclease Exonuclease Phosphatase
FORC54_RS22155	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FORC54_RS22210	COG0516	GMP reductase activity
FORC54_RS22220	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FORC54_RS22220	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FORC54_RS22240	COG2197	response regulator
FORC54_RS22245	COG3850	Histidine kinase
FORC54_RS22250	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FORC54_RS22260	COG0243	molybdopterin cofactor binding
FORC54_RS22270	COG3005	denitrification pathway
FORC54_RS22280	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
FORC54_RS22285	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
FORC54_RS22290	COG1737	Transcriptional regulator
FORC54_RS22295	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FORC54_RS22300	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FORC54_RS22305	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FORC54_RS22310	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FORC54_RS22315	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
FORC54_RS22320	COG1940	carbohydrate kinase activity
FORC54_RS22325	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FORC54_RS22345	COG0183	Belongs to the thiolase family
FORC54_RS22355	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FORC54_RS22360	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FORC54_RS22420	COG2827	Endonuclease containing a URI domain
FORC54_RS22425	COG3132	Protein of unknown function, DUF480
FORC54_RS22435	COG2926	Belongs to the UPF0265 family
FORC54_RS22445	COG2205	protein histidine kinase activity
FORC54_RS22445	COG0784	Response regulator, receiver
FORC54_RS22445	COG5002	protein histidine kinase activity
FORC54_RS22470	COG0583	DNA-binding transcription factor activity
FORC54_RS22475	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FORC54_RS22495	COG1522	sequence-specific DNA binding
FORC54_RS22500	COG0531	amino acid
FORC54_RS22505	COG0121	glutamine amidotransferase
FORC54_RS22520	COG2205	protein histidine kinase activity
FORC54_RS22525	COG0745	RESPONSE REGULATOR receiver
FORC54_RS22550	COG2239	Acts as a magnesium transporter
FORC54_RS22560	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FORC54_RS22565	COG0402	S-adenosylhomocysteine deaminase activity
FORC54_RS22570	COG1067	ATP-dependent peptidase activity
FORC54_RS22580	COG4172	Belongs to the ABC transporter superfamily
FORC54_RS22585	COG1505	serine-type exopeptidase activity
FORC54_RS22590	COG0583	DNA-binding transcription factor activity
FORC54_RS22595	COG1620	l-lactate permease
FORC54_RS22605	COG1139	Iron-sulfur cluster binding protein
FORC54_RS22635	COG2814	Major facilitator Superfamily
FORC54_RS22680	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FORC54_RS22695	COG3015	lipoprotein NlpE involved in copper resistance
FORC54_RS22700	COG1126	abc transporter atp-binding protein
FORC54_RS22705	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC54_RS22710	COG4215	(ABC) transporter
FORC54_RS22715	COG4160	amino acid transport
FORC54_RS22730	COG5002	protein histidine kinase activity
FORC54_RS22730	COG5001	Diguanylate cyclase
FORC54_RS22735	COG2755	lipolytic protein G-D-S-L family
FORC54_RS22745	COG0840	transmembrane signaling receptor activity
FORC54_RS22750	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC54_RS22780	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FORC54_RS22785	COG1028	Short-chain dehydrogenase reductase Sdr
FORC54_RS22790	COG1169	isochorismate synthase
FORC54_RS22795	COG1021	2,3-dihydroxybenzoate-AMP ligase
FORC54_RS22815	COG1021	2,3-dihydroxybenzoate-AMP ligase
FORC54_RS22825	COG4607	ABC-type enterochelin transport system periplasmic component
FORC54_RS22830	COG1629	transport
FORC54_RS22830	COG4774	siderophore transport
FORC54_RS22840	COG0189	ligase activity
FORC54_RS22845	COG4067	protein conserved in archaea
FORC54_RS22845	COG0189	ligase activity
FORC54_RS22870	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FORC54_RS22885	COG3033	Beta-eliminating lyase
FORC54_RS22890	COG0814	amino acid
FORC54_RS22895	COG0488	(ABC) transporter
FORC54_RS22905	COG1609	Transcriptional regulator
FORC54_RS22910	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC54_RS22925	COG0242	peptide deformylase activity
FORC54_RS23015	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FORC54_RS23045	COG1253	flavin adenine dinucleotide binding
FORC54_RS23050	COG1012	belongs to the aldehyde dehydrogenase family
FORC54_RS23055	COG3284	Transcriptional regulator
FORC54_RS23065	COG1879	ABC-type sugar transport system periplasmic component
FORC54_RS23070	COG0625	glutathione transferase activity
FORC54_RS23080	COG0384	phenazine biosynthesis protein PhzF
FORC54_RS23085	COG2197	response regulator
FORC54_RS23090	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FORC54_RS23095	COG0673	inositol 2-dehydrogenase activity
FORC54_RS23120	COG2015	COG2015, Alkyl sulfatase and related hydrolases
FORC54_RS23130	COG0583	DNA-binding transcription factor activity
FORC54_RS23135	COG2194	sulfuric ester hydrolase activity
FORC54_RS23140	COG0798	PFAM Bile acid sodium symporter
FORC54_RS23155	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FORC54_RS23160	COG0700	Nucleoside recognition
FORC54_RS23165	COG3366	ferrous iron transmembrane transporter activity
FORC54_RS23175	COG0366	Alpha amylase catalytic
FORC54_RS23180	COG0800	Aldolase
FORC54_RS23185	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FORC54_RS23190	COG0697	spore germination
FORC54_RS23200	COG0583	DNA-binding transcription factor activity
FORC54_RS23215	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
FORC54_RS23225	COG2985	domain, Protein
FORC54_RS23250	COG2272	Belongs to the type-B carboxylesterase lipase family
FORC54_RS23255	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FORC54_RS23260	COG0729	surface antigen
FORC54_RS23270	COG1917	Cupin 2, conserved barrel domain protein
FORC54_RS23280	COG1028	Short-chain dehydrogenase reductase Sdr
FORC54_RS23335	COG0668	transmembrane transport
FORC54_RS23375	COG0494	nUDIX hydrolase
FORC54_RS23380	COG1881	PFAM PEBP family protein
FORC54_RS23385	COG2207	Transcriptional regulator
FORC54_RS23390	COG3046	protein related to deoxyribodipyrimidine photolyase
FORC54_RS23420	COG0454	-acetyltransferase
FORC54_RS23430	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FORC54_RS23455	COG1858	cytochrome C peroxidase
FORC54_RS23470	COG2207	Transcriptional regulator
FORC54_RS23475	COG2814	Major facilitator Superfamily
FORC54_RS23495	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
FORC54_RS23505	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FORC54_RS23515	COG0583	DNA-binding transcription factor activity
FORC54_RS23535	COG0513	Belongs to the DEAD box helicase family
FORC54_RS23570	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FORC54_RS23580	COG1357	PFAM Pentapeptide repeats (8 copies)
FORC54_RS23600	COG3437	response regulator, receiver
FORC54_RS23610	COG0579	oxidoreductase
FORC54_RS23645	COG2015	COG2015, Alkyl sulfatase and related hydrolases
FORC54_RS23660	COG2205	protein histidine kinase activity
FORC54_RS23725	COG2176	DNA-directed DNA polymerase activity
FORC54_RS23730	COG1136	(ABC) transporter
FORC54_RS23730	COG0577	efflux transmembrane transporter activity
FORC54_RS23735	COG0577	efflux transmembrane transporter activity
FORC54_RS23735	COG1136	(ABC) transporter
FORC54_RS23765	COG1120	ATPase activity
FORC54_RS23770	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FORC54_RS23800	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC54_RS23805	COG3716	PTS system mannose fructose sorbose family IID component
FORC54_RS23815	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC54_RS23820	COG2222	sugar isomerase
FORC54_RS23830	COG1349	DNA-binding transcription factor activity
FORC54_RS23840	COG1349	DNA-binding transcription factor activity
FORC54_RS23855	COG2015	COG2015, Alkyl sulfatase and related hydrolases
FORC54_RS23910	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FORC54_RS23930	COG0840	transmembrane signaling receptor activity
FORC54_RS23940	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FORC54_RS23970	COG2258	MOSC domain
FORC54_RS23980	COG1757	Na H antiporter
FORC54_RS23985	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FORC54_RS23990	COG0513	Belongs to the DEAD box helicase family
FORC54_RS24000	COG2186	Transcriptional regulator
FORC54_RS24010	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FORC54_RS24020	COG0246	Mannitol dehydrogenase
FORC54_RS24025	COG1904	glucuronate isomerase
FORC54_RS24030	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FORC54_RS24035	COG0800	Aldolase
FORC54_RS24050	COG1028	Short-chain dehydrogenase reductase Sdr
FORC54_RS24055	COG2814	Major facilitator Superfamily
FORC54_RS24065	COG1902	pentaerythritol trinitrate reductase activity
FORC54_RS24090	COG0583	DNA-binding transcription factor activity
FORC54_RS24130	COG0561	phosphatase activity
FORC54_RS24135	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
FORC54_RS24140	COG3623	hexulose-6-phosphate isomerase
FORC54_RS24155	COG1132	(ABC) transporter
FORC54_RS24175	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FORC54_RS24205	COG0259	pyridoxamine-phosphate oxidase activity
FORC54_RS24215	COG2204	response regulator
FORC54_RS24250	COG0459	protein refolding
FORC54_RS24255	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FORC54_RS24270	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FORC54_RS24270	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FORC54_RS24275	COG1737	Transcriptional regulator
FORC54_RS24280	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FORC54_RS24285	COG1263	PTS System
FORC54_RS24285	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC54_RS24295	COG0406	alpha-ribazole phosphatase activity
FORC54_RS24320	COG1196	nuclear chromosome segregation
FORC54_RS24345	COG0840	transmembrane signaling receptor activity
FORC54_RS24350	COG2201	protein-glutamate methylesterase activity
FORC54_RS24355	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
FORC54_RS24360	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FORC54_RS24365	COG0840	transmembrane signaling receptor activity
FORC54_RS24370	COG0835	chemotaxis
FORC54_RS24385	COG0745	RESPONSE REGULATOR receiver
FORC54_RS24395	COG1444	tRNA N-acetyltransferase activity
FORC54_RS24485	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FORC54_RS24490	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FORC54_RS24535	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FORC54_RS24550	COG1192	Involved in chromosome partitioning