locus-tag	class	description
FORC77_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FORC77_RS00010	COG0592	DNA-directed DNA polymerase activity
FORC77_RS00020	COG0187	DNA topoisomerase II activity
FORC77_RS00025	COG0071	Belongs to the small heat shock protein (HSP20) family
FORC77_RS00035	COG3977	Valine--pyruvate aminotransferase
FORC77_RS00050	COG0752	glycyl-tRNA synthetase alpha subunit
FORC77_RS00055	COG2119	membrane
FORC77_RS00065	COG0425	Belongs to the sulfur carrier protein TusA family
FORC77_RS00080	COG0604	alcohol dehydrogenase
FORC77_RS00085	COG0183	Belongs to the thiolase family
FORC77_RS00095	COG1739	Uncharacterized protein family UPF0029
FORC77_RS00100	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FORC77_RS00150	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FORC77_RS00155	COG2960	long-chain fatty acid transporting porin activity
FORC77_RS00160	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FORC77_RS00165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FORC77_RS00170	COG1309	transcriptional regulator
FORC77_RS00210	COG4172	Belongs to the ABC transporter superfamily
FORC77_RS00215	COG4166	transmembrane transport
FORC77_RS00220	COG0601	transmembrane transport
FORC77_RS00225	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FORC77_RS00260	COG0515	serine threonine protein kinase
FORC77_RS00260	COG2815	serine threonine protein kinase
FORC77_RS00270	COG0745	RESPONSE REGULATOR receiver
FORC77_RS00275	COG1609	Transcriptional regulator
FORC77_RS00280	COG0129	dihydroxy-acid dehydratase activity
FORC77_RS00285	COG3265	gluconokinase activity
FORC77_RS00290	COG2610	gluconate transmembrane transporter activity
FORC77_RS00295	COG0800	Aldolase
FORC77_RS00310	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FORC77_RS00315	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FORC77_RS00325	COG1522	sequence-specific DNA binding
FORC77_RS00330	COG5002	protein histidine kinase activity
FORC77_RS00330	COG5001	Diguanylate cyclase
FORC77_RS00335	COG0742	ribosomal rna small subunit methyltransferase
FORC77_RS00350	COG0589	response to stress
FORC77_RS00355	COG1528	Iron-storage protein
FORC77_RS00365	COG2081	HI0933 family
FORC77_RS00375	COG2959	enzyme of heme biosynthesis
FORC77_RS00385	COG0181	hydroxymethylbilane synthase activity
FORC77_RS00390	COG3072	Adenylate cyclase
FORC77_RS00395	COG1965	Belongs to the frataxin family
FORC77_RS00405	COG0019	diaminopimelate decarboxylase activity
FORC77_RS00410	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FORC77_RS00420	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FORC77_RS00425	COG1011	Hydrolase
FORC77_RS00430	COG3287	FIST C domain
FORC77_RS00430	COG2199	diguanylate cyclase activity
FORC77_RS00430	COG2200	EAL domain
FORC77_RS00435	COG3148	PFAM DTW domain containing protein
FORC77_RS00450	COG0561	phosphatase activity
FORC77_RS00455	COG2267	carboxylic ester hydrolase activity
FORC77_RS00460	COG1280	lysine exporter protein (LysE YggA)
FORC77_RS00465	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FORC77_RS00470	COG0640	Transcriptional regulator
FORC77_RS00475	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FORC77_RS00520	COG2095	MarC family integral membrane protein
FORC77_RS00530	COG0742	ribosomal rna small subunit methyltransferase
FORC77_RS00535	COG0552	protein localization to endoplasmic reticulum
FORC77_RS00540	COG2884	Cell division ATP-binding protein ftsE
FORC77_RS00545	COG2177	Part of the ABC transporter FtsEX involved in
FORC77_RS00555	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FORC77_RS00560	COG0705	Rhomboid family
FORC77_RS00565	COG1580	Controls the rotational direction of flagella during chemotaxis
FORC77_RS00580	COG2937	Belongs to the GPAT DAPAT family
FORC77_RS00590	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FORC77_RS00600	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FORC77_RS00615	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FORC77_RS00620	COG4206	TonB-dependent receptor
FORC77_RS00695	COG3335	DDE superfamily endonuclease
FORC77_RS00705	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FORC77_RS00715	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FORC77_RS00750	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FORC77_RS00755	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FORC77_RS00770	COG0081	regulation of translation
FORC77_RS00775	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FORC77_RS00780	COG0222	ribosome binding
FORC77_RS00785	COG0085	RNA polymerase activity
FORC77_RS00790	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FORC77_RS00795	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
FORC77_RS00820	COG1573	uracil-dna glycosylase
FORC77_RS00825	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FORC77_RS00830	COG3068	Protein conserved in bacteria
FORC77_RS00835	COG1253	flavin adenine dinucleotide binding
FORC77_RS00850	COG0151	Belongs to the GarS family
FORC77_RS00855	COG0138	bifunctional purine biosynthesis protein purh
FORC77_RS00860	COG0789	Transcriptional regulator
FORC77_RS00865	COG0840	transmembrane signaling receptor activity
FORC77_RS00890	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FORC77_RS00895	COG0732	type I restriction modification DNA specificity domain
FORC77_RS00900	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
FORC77_RS00930	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FORC77_RS00945	COG0439	Biotin carboxylase
FORC77_RS00950	COG0511	ligase activity, forming carbon-carbon bonds
FORC77_RS00955	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FORC77_RS00960	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FORC77_RS00975	COG2814	Major facilitator Superfamily
FORC77_RS00980	COG2198	Histidine kinase
FORC77_RS00980	COG2205	protein histidine kinase activity
FORC77_RS00980	COG0784	Response regulator, receiver
FORC77_RS00995	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FORC77_RS01005	COG2095	MarC family integral membrane protein
FORC77_RS01020	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FORC77_RS01025	COG1027	Aspartate ammonia-lyase
FORC77_RS01035	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FORC77_RS01045	COG2205	protein histidine kinase activity
FORC77_RS01050	COG0745	RESPONSE REGULATOR receiver
FORC77_RS01055	COG3678	ATP-independent chaperone mediated protein folding
FORC77_RS01065	COG0205	6-phosphofructokinase activity
FORC77_RS01070	COG0534	Mate efflux family protein
FORC77_RS01075	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FORC77_RS01080	COG0459	protein refolding
FORC77_RS01090	COG1285	pathogenesis
FORC77_RS01095	COG1509	lysine 2,3-aminomutase activity
FORC77_RS01100	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FORC77_RS01115	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
FORC77_RS01120	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
FORC77_RS01125	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FORC77_RS01130	COG1053	succinate dehydrogenase
FORC77_RS01135	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
FORC77_RS01155	COG4942	peptidase
FORC77_RS01160	COG1045	serine acetyltransferase
FORC77_RS01165	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FORC77_RS01170	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FORC77_RS01175	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FORC77_RS01185	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FORC77_RS01200	COG0688	phosphatidylethanolamine metabolic process
FORC77_RS01205	COG1162	GTPase activity
FORC77_RS01210	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FORC77_RS01270	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FORC77_RS01275	COG0802	atpase or kinase
FORC77_RS01280	COG0860	N-Acetylmuramoyl-L-alanine amidase
FORC77_RS01295	COG1923	regulation of RNA biosynthetic process
FORC77_RS01300	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FORC77_RS01305	COG0330	HflC and HflK could
FORC77_RS01310	COG0330	HflC and HflK could
FORC77_RS01315	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
FORC77_RS01320	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FORC77_RS01325	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
FORC77_RS01330	COG1017	nitric oxide dioxygenase activity
FORC77_RS01330	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FORC77_RS01335	COG1959	2 iron, 2 sulfur cluster binding
FORC77_RS01340	COG0402	S-adenosylhomocysteine deaminase activity
FORC77_RS01345	COG0557	exoribonuclease II activity
FORC77_RS01350	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FORC77_RS01380	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FORC77_RS01390	COG1012	belongs to the aldehyde dehydrogenase family
FORC77_RS01400	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FORC77_RS01405	COG3954	Phosphoribulokinase
FORC77_RS01410	COG3089	Belongs to the UPF0270 family
FORC77_RS01415	COG0429	hydrolase of the alpha beta-hydrolase fold
FORC77_RS01425	COG0488	(ABC) transporter
FORC77_RS01430	COG2249	NAD(P)H dehydrogenase (quinone) activity
FORC77_RS01445	COG1047	Peptidyl-prolyl cis-trans
FORC77_RS01455	COG2900	Belongs to the SlyX family
FORC77_RS01465	COG0545	Peptidyl-prolyl cis-trans isomerase
FORC77_RS01470	COG2964	Protein conserved in bacteria
FORC77_RS01485	COG2168	tRNA wobble position uridine thiolation
FORC77_RS01490	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FORC77_RS01495	COG0049	tRNA binding
FORC77_RS01500	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FORC77_RS01510	COG2906	2 iron, 2 sulfur cluster binding
FORC77_RS01520	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FORC77_RS01525	COG0149	triose-phosphate isomerase activity
FORC77_RS01550	COG1494	fructose-1,6-bisphosphatase
FORC77_RS01555	COG3074	FtsZ-dependent cytokinesis
FORC77_RS01565	COG1575	Belongs to the MenA family. Type 1 subfamily
FORC77_RS01570	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FORC77_RS01575	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FORC77_RS01585	COG1609	Transcriptional regulator
FORC77_RS01590	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FORC77_RS01600	COG0281	malic enzyme
FORC77_RS01605	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
FORC77_RS01610	COG0626	cystathionine gamma-synthase activity
FORC77_RS01615	COG0460	homoserine dehydrogenase
FORC77_RS01615	COG0527	aspartate kinase activity
FORC77_RS01620	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FORC77_RS01630	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FORC77_RS01635	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FORC77_RS01645	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FORC77_RS01650	COG0137	argininosuccinate synthase activity
FORC77_RS01655	COG0165	Argininosuccinate lyase
FORC77_RS01655	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FORC77_RS01670	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FORC77_RS01700	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FORC77_RS01705	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FORC77_RS01715	COG0338	D12 class N6 adenine-specific DNA methyltransferase
FORC77_RS01720	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FORC77_RS01725	COG0360	Binds together with S18 to 16S ribosomal RNA
FORC77_RS01730	COG2965	DNA replication, synthesis of RNA primer
FORC77_RS01740	COG0359	binds to the 23S rRNA
FORC77_RS01755	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FORC77_RS01765	COG0432	Pfam Uncharacterised protein family UPF0047
FORC77_RS01780	COG0735	belongs to the Fur family
FORC77_RS01805	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FORC77_RS01825	COG0582	viral genome integration into host DNA
FORC77_RS01855	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FORC77_RS01930	COG3385	transposase activity
FORC77_RS01945	COG0527	aspartate kinase activity
FORC77_RS01955	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FORC77_RS01965	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FORC77_RS01985	COG2199	diguanylate cyclase activity
FORC77_RS01985	COG2200	EAL domain
FORC77_RS02010	COG3409	Peptidoglycan-binding domain 1 protein
FORC77_RS02010	COG3267	Type II secretory pathway component ExeA
FORC77_RS02020	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FORC77_RS02025	COG1459	type II secretion system
FORC77_RS02035	COG2165	general secretion pathway protein
FORC77_RS02040	COG2165	general secretion pathway protein
FORC77_RS02070	COG1077	Cell shape determining protein MreB Mrl
FORC77_RS02075	COG1792	Involved in formation and maintenance of cell shape
FORC77_RS02080	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FORC77_RS02085	COG0424	maF-like protein
FORC77_RS02095	COG3164	Protein of unknown function
FORC77_RS02100	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FORC77_RS02105	COG0312	modulator of DNA gyrase
FORC77_RS02110	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FORC77_RS02125	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FORC77_RS02130	COG0251	oxidation-reduction process
FORC77_RS02135	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
FORC77_RS02165	COG0456	acetyltransferase
FORC77_RS02175	COG4269	membrane
FORC77_RS02185	COG0525	valine-tRNA ligase activity
FORC77_RS02190	COG2927	DNA polymerase III (CHI subunit)
FORC77_RS02195	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FORC77_RS02200	COG0795	lipopolysaccharide-transporting ATPase activity
FORC77_RS02205	COG0795	lipopolysaccharide-transporting ATPase activity
FORC77_RS02220	COG0726	polysaccharide deacetylase
FORC77_RS02225	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FORC77_RS02235	COG1447	Phosphotransferase system cellobiose-specific component IIA
FORC77_RS02240	COG1486	melibiose metabolic process
FORC77_RS02250	COG1609	Transcriptional regulator
FORC77_RS02260	COG3437	response regulator, receiver
FORC77_RS02370	COG0741	lytic transglycosylase activity
FORC77_RS02375	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
FORC77_RS02385	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FORC77_RS02390	COG2066	Belongs to the glutaminase family
FORC77_RS02400	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FORC77_RS02405	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FORC77_RS02415	COG1872	DUF167
FORC77_RS02420	COG0762	integral membrane protein
FORC77_RS02425	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FORC77_RS02430	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FORC77_RS02445	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FORC77_RS02450	COG1678	Uncharacterized ACR, COG1678
FORC77_RS02460	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FORC77_RS02470	COG2356	endonuclease I
FORC77_RS02485	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FORC77_RS02505	COG0126	phosphoglycerate kinase activity
FORC77_RS02510	COG0191	fructose-bisphosphate aldolase activity
FORC77_RS02515	COG0668	transmembrane transport
FORC77_RS02520	COG1279	arginine transmembrane transporter activity
FORC77_RS02535	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FORC77_RS02540	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FORC77_RS02545	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FORC77_RS02555	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
FORC77_RS02560	COG3079	Belongs to the UPF0149 family
FORC77_RS02565	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FORC77_RS02570	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FORC77_RS02585	COG0354	folic acid binding
FORC77_RS02590	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FORC77_RS02600	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FORC77_RS02605	COG1595	DNA-templated transcription, initiation
FORC77_RS02620	COG3086	response to oxidative stress
FORC77_RS02625	COG0481	GTPase activity
FORC77_RS02640	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FORC77_RS02645	COG1381	Involved in DNA repair and RecF pathway recombination
FORC77_RS02650	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FORC77_RS02675	COG3437	response regulator, receiver
FORC77_RS02675	COG2205	protein histidine kinase activity
FORC77_RS02675	COG3850	Histidine kinase
FORC77_RS02675	COG4999	Histidine kinase
FORC77_RS02680	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FORC77_RS02685	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FORC77_RS02690	COG3956	TIGRFAM MazG family protein
FORC77_RS02695	COG0504	CTP synthase activity
FORC77_RS02700	COG0148	phosphopyruvate hydratase activity
FORC77_RS02705	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
FORC77_RS02715	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FORC77_RS02730	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FORC77_RS02735	COG4942	peptidase
FORC77_RS02735	COG1388	LysM domain
FORC77_RS02740	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FORC77_RS02745	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FORC77_RS02755	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FORC77_RS02765	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FORC77_RS02770	COG0527	aspartate kinase activity
FORC77_RS02775	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
FORC77_RS02820	COG3630	sodium ion export across plasma membrane
FORC77_RS02825	COG0511	ligase activity, forming carbon-carbon bonds
FORC77_RS02825	COG5016	pyruvate
FORC77_RS02830	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
FORC77_RS02840	COG1238	metal cluster binding
FORC77_RS02845	COG0612	Peptidase, M16
FORC77_RS02860	COG1854	S-ribosylhomocysteine lyase activity
FORC77_RS02865	COG4536	flavin adenine dinucleotide binding
FORC77_RS02870	COG4137	Cytochrome C assembly protein
FORC77_RS02875	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FORC77_RS02880	COG0228	four-way junction DNA binding
FORC77_RS02885	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FORC77_RS02890	COG0336	Belongs to the RNA methyltransferase TrmD family
FORC77_RS02895	COG0335	large ribosomal subunit rRNA binding
FORC77_RS02900	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FORC77_RS02920	COG1459	type II secretion system
FORC77_RS02925	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FORC77_RS02940	COG3023	N-Acetylmuramoyl-L-alanine amidase
FORC77_RS02945	COG2186	Transcriptional regulator
FORC77_RS02950	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FORC77_RS02955	COG0508	dehydrogenase complex catalyzes the overall conversion of
FORC77_RS02960	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FORC77_RS02975	COG0288	reversible hydration of carbon dioxide
FORC77_RS02980	COG0659	secondary active sulfate transmembrane transporter activity
FORC77_RS02985	COG1131	(ABC) transporter
FORC77_RS02990	COG0842	Transport permease protein
FORC77_RS03000	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FORC77_RS03005	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FORC77_RS03020	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FORC77_RS03030	COG1643	Atp-dependent helicase
FORC77_RS03035	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FORC77_RS03040	COG1752	Esterase of the alpha-beta hydrolase superfamily
FORC77_RS03045	COG1049	propionate catabolic process, 2-methylcitrate cycle
FORC77_RS03050	COG1929	Belongs to the glycerate kinase type-1 family
FORC77_RS03055	COG2610	gluconate transmembrane transporter activity
FORC77_RS03060	COG3835	regulator
FORC77_RS03065	COG3112	Uncharacterised protein family (UPF0231)
FORC77_RS03070	COG0347	Belongs to the P(II) protein family
FORC77_RS03075	COG0004	ammonium transporteR
FORC77_RS03080	COG1840	ABC-type Fe3 transport system, periplasmic component
FORC77_RS03095	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FORC77_RS03110	COG2971	BadF BadG BcrA BcrD
FORC77_RS03120	COG4608	Belongs to the ABC transporter superfamily
FORC77_RS03125	COG0444	Belongs to the ABC transporter superfamily
FORC77_RS03130	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FORC77_RS03135	COG0601	transmembrane transport
FORC77_RS03145	COG2205	protein histidine kinase activity
FORC77_RS03145	COG0784	Response regulator, receiver
FORC77_RS03150	COG2813	Specifically methylates the guanine in position
FORC77_RS03155	COG0628	permease
FORC77_RS03165	COG0316	Belongs to the HesB IscA family
FORC77_RS03180	COG0739	heme binding
FORC77_RS03185	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FORC77_RS03190	COG2832	Protein of unknown function (DUF454)
FORC77_RS03195	COG2027	D-alanyl-D-alanine carboxypeptidase
FORC77_RS03210	COG1534	Rna-binding protein
FORC77_RS03215	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FORC77_RS03220	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FORC77_RS03225	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FORC77_RS03230	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FORC77_RS03235	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FORC77_RS03250	COG0779	Required for maturation of 30S ribosomal subunits
FORC77_RS03255	COG0195	Participates in both transcription termination and antitermination
FORC77_RS03265	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FORC77_RS03270	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FORC77_RS03275	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FORC77_RS03305	COG1185	polyribonucleotide nucleotidyltransferase activity
FORC77_RS03320	COG0534	Mate efflux family protein
FORC77_RS03325	COG3385	transposase activity
FORC77_RS03330	COG0826	peptidase U32
FORC77_RS03335	COG0826	peptidase U32
FORC77_RS03345	COG3154	lipid carrier protein
FORC77_RS03350	COG3153	acetyltransferase
FORC77_RS03360	COG0456	acetyltransferase
FORC77_RS03370	COG3706	GGDEF domain
FORC77_RS03380	COG0084	hydrolase, TatD family'
FORC77_RS03385	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FORC77_RS03390	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FORC77_RS03395	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FORC77_RS03400	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FORC77_RS03405	COG0813	purine-nucleoside phosphorylase activity
FORC77_RS03415	COG0560	Phosphoserine phosphatase
FORC77_RS03425	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FORC77_RS03445	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FORC77_RS03450	COG0583	DNA-binding transcription factor activity
FORC77_RS03460	COG1022	Amp-dependent synthetase and ligase
FORC77_RS03495	COG4964	Belongs to the GSP D family
FORC77_RS03545	COG2059	Chromate
FORC77_RS03550	COG0583	DNA-binding transcription factor activity
FORC77_RS03560	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
FORC77_RS03560	COG3408	Glycogen debranching enzyme
FORC77_RS03565	COG0531	amino acid
FORC77_RS03570	COG0531	amino acid
FORC77_RS03575	COG2731	YhcH YjgK YiaL family protein
FORC77_RS03580	COG3250	beta-galactosidase activity
FORC77_RS03590	COG1609	Transcriptional regulator
FORC77_RS03595	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FORC77_RS03605	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FORC77_RS03610	COG2017	converts alpha-aldose to the beta-anomer
FORC77_RS03615	COG0840	transmembrane signaling receptor activity
FORC77_RS03625	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FORC77_RS03640	COG0189	ligase activity
FORC77_RS03640	COG0569	domain protein
FORC77_RS03655	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FORC77_RS03660	COG1349	DNA-binding transcription factor activity
FORC77_RS03665	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FORC77_RS03670	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FORC77_RS03675	COG2171	N-acyltransferase activity
FORC77_RS03680	COG3141	response to X-ray
FORC77_RS03695	COG3083	sulfuric ester hydrolase activity
FORC77_RS03700	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FORC77_RS03730	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FORC77_RS03735	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FORC77_RS03740	COG2166	iron-sulfur cluster assembly
FORC77_RS03755	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FORC77_RS03760	COG0693	protein deglycase activity
FORC77_RS03765	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FORC77_RS03780	COG1595	DNA-templated transcription, initiation
FORC77_RS03790	COG2211	Major facilitator Superfamily
FORC77_RS03805	COG2813	Specifically methylates the guanine in position
FORC77_RS03810	COG0271	Belongs to the BolA IbaG family
FORC77_RS03815	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FORC77_RS03820	COG1805	sodium ion transport
FORC77_RS03825	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FORC77_RS03835	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FORC77_RS03840	COG2871	sodium ion transport
FORC77_RS03845	COG1477	protein flavinylation
FORC77_RS03860	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FORC77_RS03865	COG0514	ATP-dependent DNA helicase (RecQ)
FORC77_RS03880	COG0733	neurotransmitter:sodium symporter activity
FORC77_RS03905	COG1720	tRNA m6t6A37 methyltransferase activity
FORC77_RS03910	COG0254	rRNA binding
FORC77_RS03940	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FORC77_RS03980	COG3098	single-species biofilm formation
FORC77_RS03995	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FORC77_RS04000	COG0024	Methionine aminopeptidase
FORC77_RS04005	COG0052	Belongs to the universal ribosomal protein uS2 family
FORC77_RS04010	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FORC77_RS04015	COG0528	UMP kinase activity
FORC77_RS04020	COG0233	cytoplasmic translational termination
FORC77_RS04025	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FORC77_RS04030	COG0575	Belongs to the CDS family
FORC77_RS04035	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FORC77_RS04040	COG0750	zinc metalloprotease
FORC77_RS04045	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FORC77_RS04050	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
FORC77_RS04060	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FORC77_RS04065	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FORC77_RS04070	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FORC77_RS04075	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FORC77_RS04080	COG0587	DNA-directed DNA polymerase activity
FORC77_RS04085	COG0825	malonyl-CoA metabolic process
FORC77_RS04100	COG0347	Belongs to the P(II) protein family
FORC77_RS04105	COG3021	interspecies interaction between organisms
FORC77_RS04115	COG0741	lytic transglycosylase activity
FORC77_RS04115	COG1388	LysM domain
FORC77_RS04120	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FORC77_RS04125	COG2226	methyltransferase
FORC77_RS04130	COG0328	RNA-DNA hybrid ribonuclease activity
FORC77_RS04145	COG2249	NAD(P)H dehydrogenase (quinone) activity
FORC77_RS04175	COG1960	acyl-CoA dehydrogenase activity
FORC77_RS04185	COG0121	glutamine amidotransferase
FORC77_RS04190	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FORC77_RS04195	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FORC77_RS04200	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FORC77_RS04205	COG2233	PERMEase
FORC77_RS04225	COG1393	Belongs to the ArsC family
FORC77_RS04230	COG4783	chaperone-mediated protein folding
FORC77_RS04245	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FORC77_RS04250	COG2716	regulation of RNA biosynthetic process
FORC77_RS04255	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FORC77_RS04260	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
FORC77_RS04265	COG3385	transposase activity
FORC77_RS04285	COG1393	Belongs to the ArsC family
FORC77_RS04310	COG2837	iron assimilation
FORC77_RS04315	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FORC77_RS04320	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FORC77_RS04325	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FORC77_RS04330	COG1334	flagellar protein FlaG
FORC77_RS04335	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FORC77_RS04345	COG1516	flagellar protein fliS
FORC77_RS04365	COG1677	Flagellar hook-basal body complex protein FliE
FORC77_RS04375	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FORC77_RS04425	COG1987	bacterial-type flagellum assembly
FORC77_RS04430	COG1684	flagellar biosynthetic protein fliR
FORC77_RS04465	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
FORC77_RS04470	COG0784	Response regulator, receiver
FORC77_RS04470	COG2198	Histidine kinase
FORC77_RS04470	COG0643	Histidine kinase
FORC77_RS04475	COG2201	protein-glutamate methylesterase activity
FORC77_RS04480	COG1192	Involved in chromosome partitioning
FORC77_RS04490	COG0835	chemotaxis
FORC77_RS04500	COG4133	protoheme IX ABC transporter activity
FORC77_RS04505	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FORC77_RS04510	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FORC77_RS04515	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FORC77_RS04520	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
FORC77_RS04525	COG1138	Cytochrome C-type biogenesis protein
FORC77_RS04530	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FORC77_RS04535	COG3088	subunit of a heme lyase
FORC77_RS04535	COG4235	cytochrome complex assembly
FORC77_RS04545	COG2853	Lipoprotein
FORC77_RS04550	COG2067	long-chain fatty acid transport protein
FORC77_RS04555	COG2067	long-chain fatty acid transport protein
FORC77_RS04575	COG1024	Enoyl-CoA hydratase
FORC77_RS04575	COG1250	3-hydroxyacyl-CoA dehydrogenase
FORC77_RS04580	COG1025	Belongs to the peptidase M16 family
FORC77_RS04590	COG2062	phosphohistidine phosphatase, SixA
FORC77_RS04595	COG2840	Smr protein MutS2
FORC77_RS04600	COG2890	protein-(glutamine-N5) methyltransferase activity
FORC77_RS04605	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FORC77_RS04610	COG2860	membrane
FORC77_RS04615	COG3101	peptidyl-lysine hydroxylation
FORC77_RS04625	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FORC77_RS04625	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FORC77_RS04630	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FORC77_RS04640	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FORC77_RS04650	COG0101	tRNA pseudouridine synthase activity
FORC77_RS04655	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FORC77_RS04660	COG0285	dihydrofolate synthase activity
FORC77_RS04665	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
FORC77_RS04670	COG1286	toxin biosynthetic process
FORC77_RS04675	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FORC77_RS04680	COG0583	DNA-binding transcription factor activity
FORC77_RS04685	COG0745	RESPONSE REGULATOR receiver
FORC77_RS04695	COG2832	Protein of unknown function (DUF454)
FORC77_RS04700	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FORC77_RS04710	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FORC77_RS04715	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FORC77_RS04730	COG2205	protein histidine kinase activity
FORC77_RS04735	COG0745	RESPONSE REGULATOR receiver
FORC77_RS04750	COG2983	Belongs to the UPF0260 family
FORC77_RS04760	COG0346	lactoylglutathione lyase activity
FORC77_RS04770	COG1785	Belongs to the alkaline phosphatase family
FORC77_RS04785	COG2226	methyltransferase
FORC77_RS04790	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FORC77_RS04800	COG2239	Acts as a magnesium transporter
FORC77_RS04805	COG2203	Gaf domain
FORC77_RS04805	COG2199	diguanylate cyclase activity
FORC77_RS04825	COG3710	Transcriptional regulator
FORC77_RS04830	COG0531	amino acid
FORC77_RS04835	COG1982	Orn Lys Arg decarboxylase major
FORC77_RS04840	COG3706	GGDEF domain
FORC77_RS04845	COG0517	IMP dehydrogenase activity
FORC77_RS04845	COG0617	tRNA 3'-terminal CCA addition
FORC77_RS04845	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FORC77_RS04870	COG0537	adenosine 5'-monophosphoramidase activity
FORC77_RS04900	COG1252	NADH dehydrogenase
FORC77_RS04915	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FORC77_RS04925	COG4591	ABC-type transport system involved in lipoprotein release permease component
FORC77_RS04930	COG1136	(ABC) transporter
FORC77_RS04935	COG4591	ABC-type transport system involved in lipoprotein release permease component
FORC77_RS04945	COG0658	competence protein
FORC77_RS04945	COG2333	competence protein COMEC
FORC77_RS04950	COG1132	(ABC) transporter
FORC77_RS04955	COG1663	tetraacyldisaccharide 4'-kinase activity
FORC77_RS04960	COG2835	tetraacyldisaccharide 4'-kinase activity
FORC77_RS04965	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FORC77_RS04970	COG2199	diguanylate cyclase activity
FORC77_RS04975	COG2719	SpoVR family
FORC77_RS04980	COG2718	Belongs to the UPF0229 family
FORC77_RS04985	COG2766	serine protein kinase
FORC77_RS04990	COG3013	Belongs to the UPF0304 family
FORC77_RS05000	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FORC77_RS05015	COG1882	Formate acetyltransferase
FORC77_RS05055	COG0708	Exodeoxyribonuclease III
FORC77_RS05060	COG0840	transmembrane signaling receptor activity
FORC77_RS05070	COG3923	Primosomal replication protein n
FORC77_RS05080	COG1199	ATP-dependent helicase activity
FORC77_RS05085	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FORC77_RS05105	COG1278	Cold shock
FORC77_RS05110	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FORC77_RS05115	COG0542	response to heat
FORC77_RS05120	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FORC77_RS05125	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FORC77_RS05140	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FORC77_RS05150	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FORC77_RS05165	COG0297	glycogen (starch) synthase activity
FORC77_RS05185	COG3070	regulator of competence-specific genes
FORC77_RS05190	COG1609	Transcriptional regulator
FORC77_RS05200	COG0745	RESPONSE REGULATOR receiver
FORC77_RS05205	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FORC77_RS05210	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FORC77_RS05220	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
FORC77_RS05225	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FORC77_RS05255	COG0189	ligase activity
FORC77_RS05255	COG4067	protein conserved in archaea
FORC77_RS05260	COG0500	methyltransferase
FORC77_RS05265	COG4106	trans-aconitate 2-methyltransferase activity
FORC77_RS05285	COG0840	transmembrane signaling receptor activity
FORC77_RS05290	COG0632	four-way junction helicase activity
FORC77_RS05295	COG2255	four-way junction helicase activity
FORC77_RS05300	COG1271	oxidase subunit
FORC77_RS05305	COG1294	oxidase, subunit
FORC77_RS05310	COG4890	Cyd operon protein YbgT
FORC77_RS05320	COG0824	Thioesterase
FORC77_RS05325	COG0811	peptide transport
FORC77_RS05330	COG0848	biopolymer transport protein
FORC77_RS05340	COG0823	Involved in the tonB-independent uptake of proteins
FORC77_RS05345	COG2885	chlorophyll binding
FORC77_RS05350	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
FORC77_RS05355	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FORC77_RS05365	COG3766	membrane
FORC77_RS05375	COG0754	glutathionylspermidine amidase activity
FORC77_RS05385	COG0784	Response regulator, receiver
FORC77_RS05385	COG2205	protein histidine kinase activity
FORC77_RS05465	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FORC77_RS05480	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FORC77_RS05485	COG0840	transmembrane signaling receptor activity
FORC77_RS05490	COG1349	DNA-binding transcription factor activity
FORC77_RS05495	COG0738	Major facilitator superfamily
FORC77_RS05505	COG1070	Carbohydrate kinase
FORC77_RS05510	COG4154	Belongs to the RbsD FucU family
FORC77_RS05515	COG0235	Class ii aldolase
FORC77_RS05520	COG1454	alcohol dehydrogenase
FORC77_RS05525	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FORC77_RS05530	COG0861	Integral membrane protein TerC family
FORC77_RS05555	COG2207	Transcriptional regulator
FORC77_RS05575	COG1032	radical SAM domain protein
FORC77_RS05600	COG0583	DNA-binding transcription factor activity
FORC77_RS05610	COG0280	phosphate acetyltransferase
FORC77_RS05610	COG0857	belongs to the CobB CobQ family
FORC77_RS05615	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FORC77_RS05620	COG3092	negative regulation of chromosome organization
FORC77_RS05630	COG4120	Belongs to the binding-protein-dependent transport system permease family
FORC77_RS05640	COG0366	Alpha amylase catalytic
FORC77_RS05645	COG2199	diguanylate cyclase activity
FORC77_RS05655	COG0653	protein targeting
FORC77_RS05665	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FORC77_RS05670	COG2186	Transcriptional regulator
FORC77_RS05685	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FORC77_RS05710	COG1846	Transcriptional regulator
FORC77_RS05715	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FORC77_RS05720	COG0840	transmembrane signaling receptor activity
FORC77_RS05740	COG1448	Aminotransferase
FORC77_RS05745	COG3437	response regulator, receiver
FORC77_RS05745	COG2770	Histidine kinase
FORC77_RS05760	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FORC77_RS05770	COG0017	Asparaginyl-tRNA synthetase
FORC77_RS05775	COG0840	transmembrane signaling receptor activity
FORC77_RS05780	COG0720	synthase
FORC77_RS05790	COG2200	EAL domain
FORC77_RS05795	COG1760	l-serine dehydratase
FORC77_RS05800	COG0814	amino acid
FORC77_RS05805	COG0494	nUDIX hydrolase
FORC77_RS05815	COG2205	protein histidine kinase activity
FORC77_RS05815	COG0784	Response regulator, receiver
FORC77_RS05825	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FORC77_RS05840	COG3106	COG3106 Predicted ATPase
FORC77_RS05845	COG3768	UPF0283 membrane protein
FORC77_RS05850	COG3283	Transcriptional regulator of aromatic amino acids metabolism
FORC77_RS05855	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC77_RS05870	COG0471	metal ion transport
FORC77_RS05875	COG4191	Histidine kinase
FORC77_RS05875	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC77_RS05885	COG3706	GGDEF domain
FORC77_RS05890	COG2199	diguanylate cyclase activity
FORC77_RS05890	COG2200	EAL domain
FORC77_RS05905	COG3300	MHYT domain
FORC77_RS05905	COG5001	Diguanylate cyclase
FORC77_RS05910	COG1328	CTP reductase activity
FORC77_RS05915	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FORC77_RS05920	COG0583	DNA-binding transcription factor activity
FORC77_RS05935	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FORC77_RS05940	COG4667	esterase of the alpha-beta hydrolase superfamily
FORC77_RS05950	COG1597	lipid kinase activity
FORC77_RS05955	COG0814	amino acid
FORC77_RS05970	COG0783	Belongs to the Dps family
FORC77_RS05985	COG1132	(ABC) transporter
FORC77_RS05990	COG1132	(ABC) transporter
FORC77_RS05995	COG1115	amino acid carrier protein
FORC77_RS06010	COG1596	polysaccharide export
FORC77_RS06035	COG0438	transferase activity, transferring glycosyl groups
FORC77_RS06040	COG0438	transferase activity, transferring glycosyl groups
FORC77_RS06040	COG0297	glycogen (starch) synthase activity
FORC77_RS06055	COG2165	general secretion pathway protein
FORC77_RS06080	COG0443	Heat shock 70 kDa protein
FORC77_RS06085	COG0443	Heat shock 70 kDa protein
FORC77_RS06095	COG3706	GGDEF domain
FORC77_RS06115	COG3713	MltA-interacting MipA family protein
FORC77_RS06145	COG4964	Belongs to the GSP D family
FORC77_RS06155	COG2894	cell division
FORC77_RS06195	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FORC77_RS06210	COG1643	Atp-dependent helicase
FORC77_RS06235	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
FORC77_RS06240	COG5380	lipid catabolic process
FORC77_RS06245	COG2814	Major facilitator Superfamily
FORC77_RS06260	COG0840	transmembrane signaling receptor activity
FORC77_RS06265	COG0010	Belongs to the arginase family
FORC77_RS06270	COG1166	arginine decarboxylase activity
FORC77_RS06335	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FORC77_RS06340	COG0072	phenylalanine-tRNA ligase activity
FORC77_RS06340	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FORC77_RS06345	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FORC77_RS06360	COG0776	regulation of translation
FORC77_RS06370	COG0500	methyltransferase
FORC77_RS06375	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
FORC77_RS06380	COG0295	cytidine deaminase activity
FORC77_RS06395	COG2885	chlorophyll binding
FORC77_RS06410	COG0247	lactate metabolic process
FORC77_RS06410	COG0277	FAD linked oxidase domain protein
FORC77_RS06415	COG2020	methyltransferase activity
FORC77_RS06420	COG5640	endopeptidase activity
FORC77_RS06430	COG2986	histidine ammonia-lyase
FORC77_RS06435	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FORC77_RS06440	COG0010	Belongs to the arginase family
FORC77_RS06445	COG1228	amidohydrolase
FORC77_RS06455	COG4326	sporulation control protein
FORC77_RS06475	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FORC77_RS06770	COG2801	Transposase and inactivated derivatives
FORC77_RS06820	COG0582	viral genome integration into host DNA
FORC77_RS06985	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC77_RS07055	COG0625	glutathione transferase activity
FORC77_RS07085	COG3738	Protein conserved in bacteria
FORC77_RS07180	COG0582	viral genome integration into host DNA
FORC77_RS07320	COG1942	4-Oxalocrotonate Tautomerase
FORC77_RS07355	COG4628	conserved protein (DUF2132)
FORC77_RS07620	COG1942	4-Oxalocrotonate Tautomerase
FORC77_RS07655	COG2801	Transposase and inactivated derivatives
FORC77_RS07720	COG0456	acetyltransferase
FORC77_RS07825	COG0384	phenazine biosynthesis protein PhzF
FORC77_RS08100	COG0534	Mate efflux family protein
FORC77_RS08105	COG0307	riboflavin synthase, alpha
FORC77_RS08125	COG3706	GGDEF domain
FORC77_RS08135	COG0791	NLP P60 protein
FORC77_RS08140	COG0840	transmembrane signaling receptor activity
FORC77_RS08150	COG3148	PFAM DTW domain containing protein
FORC77_RS08155	COG1940	carbohydrate kinase activity
FORC77_RS08175	COG3842	ATPase activity
FORC77_RS08180	COG4662	Binding-protein-dependent transport system inner membrane component
FORC77_RS08190	COG2204	response regulator
FORC77_RS08195	COG3852	Histidine kinase
FORC77_RS08210	COG0488	(ABC) transporter
FORC77_RS08220	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FORC77_RS08250	COG0243	molybdopterin cofactor binding
FORC77_RS08250	COG3383	formate dehydrogenase (NAD+) activity
FORC77_RS08255	COG0437	4 iron, 4 sulfur cluster binding
FORC77_RS08285	COG0004	ammonium transporteR
FORC77_RS08290	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FORC77_RS08295	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FORC77_RS08305	COG1177	transmembrane transport
FORC77_RS08310	COG1176	ABC-type spermidine putrescine transport system, permease component I
FORC77_RS08315	COG3842	ATPase activity
FORC77_RS08325	COG2992	FlgJ-related protein
FORC77_RS08335	COG0037	tRNA processing
FORC77_RS08340	COG0589	response to stress
FORC77_RS08345	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FORC77_RS08360	COG2217	Heavy metal translocating P-type atpase
FORC77_RS08370	COG2010	Cytochrome c
FORC77_RS08385	COG3278	Belongs to the heme-copper respiratory oxidase family
FORC77_RS08400	COG2205	protein histidine kinase activity
FORC77_RS08400	COG0784	Response regulator, receiver
FORC77_RS08420	COG3120	sequence-specific DNA binding
FORC77_RS08425	COG1067	ATP-dependent peptidase activity
FORC77_RS08430	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FORC77_RS08445	COG0488	(ABC) transporter
FORC77_RS08455	COG0116	Belongs to the methyltransferase superfamily
FORC77_RS08455	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FORC77_RS08470	COG2902	Dehydrogenase
FORC77_RS08480	COG0308	aminopeptidase N
FORC77_RS08495	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
FORC77_RS08500	COG1956	GAF domain-containing protein
FORC77_RS08505	COG1132	(ABC) transporter
FORC77_RS08510	COG2995	paraquat-inducible protein a
FORC77_RS08515	COG3008	intermembrane lipid transfer
FORC77_RS08520	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
FORC77_RS08520	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FORC77_RS08525	COG2996	Protein conserved in bacteria
FORC77_RS08540	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FORC77_RS08550	COG3706	GGDEF domain
FORC77_RS08555	COG1793	dna ligase
FORC77_RS08590	COG2204	response regulator
FORC77_RS08635	COG0438	transferase activity, transferring glycosyl groups
FORC77_RS08645	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FORC77_RS08685	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FORC77_RS08690	COG0363	glucosamine-6-phosphate deaminase activity
FORC77_RS08695	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FORC77_RS08700	COG4565	transcriptional regulatory protein
FORC77_RS08705	COG3290	protein histidine kinase activity
FORC77_RS08720	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FORC77_RS08745	COG1115	amino acid carrier protein
FORC77_RS08760	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
FORC77_RS08765	COG0204	Acyl-transferase
FORC77_RS08770	COG0348	domain, Protein
FORC77_RS08775	COG0437	4 iron, 4 sulfur cluster binding
FORC77_RS08785	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC77_RS08790	COG4597	amino acid ABC transporter
FORC77_RS08795	COG0765	amino acid transport
FORC77_RS08800	COG1126	abc transporter atp-binding protein
FORC77_RS08805	COG0670	Belongs to the BI1 family
FORC77_RS08815	COG2920	part of a sulfur-relay system
FORC77_RS08830	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FORC77_RS08855	COG3706	GGDEF domain
FORC77_RS08860	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FORC77_RS08865	COG0602	queuosine metabolic process
FORC77_RS08870	COG0561	phosphatase activity
FORC77_RS08900	COG2828	Protein conserved in bacteria
FORC77_RS08905	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FORC77_RS08910	COG0372	Belongs to the citrate synthase family
FORC77_RS08915	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FORC77_RS08960	COG2197	response regulator
FORC77_RS08970	COG0730	response to heat
FORC77_RS08985	COG1653	transport
FORC77_RS08990	COG1175	transmembrane transport
FORC77_RS08995	COG0395	ABC-type sugar transport system, permease component
FORC77_RS09005	COG1349	DNA-binding transcription factor activity
FORC77_RS09010	COG0584	glycerophosphoryl diester phosphodiesterase
FORC77_RS09025	COG1278	Cold shock
FORC77_RS09065	COG0625	glutathione transferase activity
FORC77_RS09075	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
FORC77_RS09085	COG2195	Cleaves the N-terminal amino acid of tripeptides
FORC77_RS09100	COG3063	Type IV pilus biogenesis stability protein PilW
FORC77_RS09115	COG1451	nucleotide metabolic process
FORC77_RS09125	COG0583	DNA-binding transcription factor activity
FORC77_RS09145	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
FORC77_RS09155	COG2988	succinylglutamate desuccinylase activity
FORC77_RS09175	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FORC77_RS09195	COG2925	Exonuclease
FORC77_RS09200	COG1380	Effector of murein hydrolase LrgA
FORC77_RS09205	COG1346	cytolysis
FORC77_RS09215	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FORC77_RS09230	COG1643	Atp-dependent helicase
FORC77_RS09235	COG0281	malic enzyme
FORC77_RS09240	COG2949	membrane
FORC77_RS09245	COG0471	metal ion transport
FORC77_RS09270	COG0492	ferredoxin-NADP+ reductase activity
FORC77_RS09275	COG4988	ABC transporter
FORC77_RS09280	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FORC77_RS09295	COG5002	protein histidine kinase activity
FORC77_RS09295	COG5002	protein histidine kinase activity
FORC77_RS09310	COG3070	regulator of competence-specific genes
FORC77_RS09320	COG2431	L-lysine efflux transmembrane transporter activity
FORC77_RS09330	COG0076	glutamate decarboxylase activity
FORC77_RS09335	COG1737	Transcriptional regulator
FORC77_RS09340	COG1979	alcohol dehydrogenase
FORC77_RS09345	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FORC77_RS09350	COG3273	potassium ion transport
FORC77_RS09350	COG2985	domain, Protein
FORC77_RS09370	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FORC77_RS09385	COG1136	(ABC) transporter
FORC77_RS09390	COG0702	epimerase
FORC77_RS09405	COG2814	Major facilitator Superfamily
FORC77_RS09415	COG1061	Type III restriction enzyme res subunit
FORC77_RS09430	COG2205	protein histidine kinase activity
FORC77_RS09435	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FORC77_RS09460	COG3313	Fe-S protein
FORC77_RS09470	COG4134	Bacterial extracellular solute-binding protein
FORC77_RS09475	COG4135	transport system, permease component
FORC77_RS09480	COG4136	ATPase activity
FORC77_RS09485	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FORC77_RS09490	COG3604	Transcriptional regulator
FORC77_RS09495	COG1151	hydroxylamine reductase activity
FORC77_RS09500	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FORC77_RS09510	COG0564	pseudouridine synthase activity
FORC77_RS09520	COG0733	neurotransmitter:sodium symporter activity
FORC77_RS09530	COG0626	cystathionine gamma-synthase activity
FORC77_RS09535	COG2818	Glycosylase
FORC77_RS09545	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FORC77_RS09555	COG1983	PspC domain protein
FORC77_RS09565	COG1842	Phage shock protein A
FORC77_RS09570	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
FORC77_RS09595	COG4172	Belongs to the ABC transporter superfamily
FORC77_RS09610	COG1227	inorganic diphosphatase activity
FORC77_RS09645	COG3005	denitrification pathway
FORC77_RS09650	COG4459	periplasmic nitrate reductase
FORC77_RS09655	COG0390	transport system, permease component
FORC77_RS09660	COG2116	formate transmembrane transporter activity
FORC77_RS09680	COG0583	DNA-binding transcription factor activity
FORC77_RS09685	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FORC77_RS09695	COG1435	thymidine kinase activity
FORC77_RS09700	COG0215	cysteine-tRNA ligase activity
FORC77_RS09705	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FORC77_RS09710	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FORC77_RS09715	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FORC77_RS09720	COG3012	SEC-C Motif Domain Protein
FORC77_RS09735	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FORC77_RS09740	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FORC77_RS09745	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FORC77_RS09745	COG0131	Imidazoleglycerol-phosphate dehydratase
FORC77_RS09750	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FORC77_RS09760	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FORC77_RS09765	COG1757	Na H antiporter
FORC77_RS09770	COG2916	Histone family protein nucleoid-structuring protein H-NS
FORC77_RS09775	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FORC77_RS09785	COG0482	sulfurtransferase activity
FORC77_RS09790	COG2915	High frequency lysogenization protein hflD homolog
FORC77_RS09795	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FORC77_RS09830	COG1028	Short-chain dehydrogenase reductase Sdr
FORC77_RS09840	COG0501	Belongs to the peptidase M48B family
FORC77_RS09845	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FORC77_RS09850	COG2226	methyltransferase
FORC77_RS09860	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FORC77_RS09865	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FORC77_RS09875	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FORC77_RS09880	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FORC77_RS09895	COG0686	Belongs to the AlaDH PNT family
FORC77_RS09905	COG0583	DNA-binding transcription factor activity
FORC77_RS09935	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FORC77_RS09940	COG3108	Peptidase M15
FORC77_RS09945	COG2989	Protein conserved in bacteria
FORC77_RS09985	COG4608	Belongs to the ABC transporter superfamily
FORC77_RS09990	COG0444	Belongs to the ABC transporter superfamily
FORC77_RS09995	COG4166	transmembrane transport
FORC77_RS10000	COG4239	(ABC) transporter, permease
FORC77_RS10005	COG4174	ABC transporter (Permease)
FORC77_RS10015	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
FORC77_RS10020	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
FORC77_RS10030	COG0539	negative regulation of cytoplasmic translation
FORC77_RS10040	COG0616	signal peptide processing
FORC77_RS10045	COG1028	Short-chain dehydrogenase reductase Sdr
FORC77_RS10065	COG0784	Response regulator, receiver
FORC77_RS10065	COG0835	chemotaxis
FORC77_RS10070	COG1940	carbohydrate kinase activity
FORC77_RS10075	COG0469	pyruvate kinase activity
FORC77_RS10080	COG4667	esterase of the alpha-beta hydrolase superfamily
FORC77_RS10095	COG0733	neurotransmitter:sodium symporter activity
FORC77_RS10110	COG1263	PTS System
FORC77_RS10110	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC77_RS10115	COG0084	hydrolase, TatD family'
FORC77_RS10125	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FORC77_RS10130	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FORC77_RS10145	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FORC77_RS10160	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FORC77_RS10165	COG0416	fatty acid biosynthetic process
FORC77_RS10170	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FORC77_RS10175	COG1399	metal-binding, possibly nucleic acid-binding protein
FORC77_RS10180	COG0424	maF-like protein
FORC77_RS10190	COG1530	ribonuclease E activity
FORC77_RS10195	COG0659	secondary active sulfate transmembrane transporter activity
FORC77_RS10200	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FORC77_RS10205	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
FORC77_RS10215	COG0572	uridine kinase
FORC77_RS10220	COG0489	protein tyrosine kinase activity
FORC77_RS10225	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FORC77_RS10225	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FORC77_RS10235	COG4235	cytochrome complex assembly
FORC77_RS10235	COG3088	subunit of a heme lyase
FORC77_RS10240	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FORC77_RS10245	COG1138	Cytochrome C-type biogenesis protein
FORC77_RS10250	COG3301	Polysulphide reductase, NrfD
FORC77_RS10255	COG0437	4 iron, 4 sulfur cluster binding
FORC77_RS10260	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
FORC77_RS10265	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
FORC77_RS10285	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FORC77_RS10290	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FORC77_RS10295	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FORC77_RS10365	COG2197	response regulator
FORC77_RS10370	COG0417	DNA replication proofreading
FORC77_RS10375	COG5001	Diguanylate cyclase
FORC77_RS10385	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FORC77_RS10405	COG0009	L-threonylcarbamoyladenylate synthase
FORC77_RS10410	COG0613	PHP domain protein
FORC77_RS10420	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FORC77_RS10425	COG0512	Glutamine amidotransferase of anthranilate synthase
FORC77_RS10430	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FORC77_RS10435	COG0134	indole-3-glycerol-phosphate synthase activity
FORC77_RS10435	COG0135	phosphoribosylanthranilate isomerase activity
FORC77_RS10440	COG0133	tryptophan synthase activity
FORC77_RS10450	COG1301	dicarboxylic acid transport
FORC77_RS10470	COG2350	Protein conserved in bacteria
FORC77_RS10480	COG0435	Glutathione S-transferase
FORC77_RS10490	COG0444	Belongs to the ABC transporter superfamily
FORC77_RS10495	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FORC77_RS10500	COG0601	transmembrane transport
FORC77_RS10510	COG0314	molybdopterin synthase activity
FORC77_RS10515	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FORC77_RS10520	COG0315	cyclic pyranopterin monophosphate synthase activity
FORC77_RS10525	COG0521	Mo-molybdopterin cofactor biosynthetic process
FORC77_RS10535	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FORC77_RS10540	COG2198	Histidine kinase
FORC77_RS10545	COG2204	response regulator
FORC77_RS10550	COG0556	nucleotide-excision repair
FORC77_RS10565	COG4657	Part of a membrane complex involved in electron transport
FORC77_RS10570	COG2878	Part of a membrane complex involved in electron transport
FORC77_RS10575	COG4656	Part of a membrane complex involved in electron transport
FORC77_RS10580	COG4658	electron transport chain
FORC77_RS10585	COG4659	FMN binding
FORC77_RS10590	COG4660	Part of a membrane complex involved in electron transport
FORC77_RS10595	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FORC77_RS10600	COG0346	lactoylglutathione lyase activity
FORC77_RS10610	COG2885	chlorophyll binding
FORC77_RS10615	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FORC77_RS10620	COG2056	Na+-H+ antiporter family
FORC77_RS10630	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FORC77_RS10645	COG1028	Short-chain dehydrogenase reductase Sdr
FORC77_RS10650	COG1454	alcohol dehydrogenase
FORC77_RS10650	COG1012	belongs to the aldehyde dehydrogenase family
FORC77_RS10655	COG2095	MarC family integral membrane protein
FORC77_RS10660	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FORC77_RS10675	COG1757	Na H antiporter
FORC77_RS10690	COG3081	Nucleoid-associated protein
FORC77_RS10700	COG3083	sulfuric ester hydrolase activity
FORC77_RS10710	COG0569	domain protein
FORC77_RS10715	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FORC77_RS10720	COG2731	YhcH YjgK YiaL family protein
FORC77_RS10725	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FORC77_RS10735	COG2205	protein histidine kinase activity
FORC77_RS10735	COG0784	Response regulator, receiver
FORC77_RS10740	COG0123	including yeast histone deacetylase and acetoin utilization protein
FORC77_RS10750	COG0778	Nitroreductase
FORC77_RS10755	COG1902	pentaerythritol trinitrate reductase activity
FORC77_RS10755	COG0446	pyridine nucleotide-disulphide oxidoreductase
FORC77_RS10760	COG0616	signal peptide processing
FORC77_RS10765	COG0252	asparaginase activity
FORC77_RS10770	COG3139	Protein of unknown function (DUF1315)
FORC77_RS10785	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FORC77_RS10835	COG3126	Type III secretion system lipoprotein chaperone (YscW)
FORC77_RS10840	COG1946	Acyl-CoA thioesterase
FORC77_RS10850	COG1522	sequence-specific DNA binding
FORC77_RS10855	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FORC77_RS10870	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FORC77_RS10875	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FORC77_RS10925	COG0318	PFAM AMP-dependent synthetase and ligase
FORC77_RS10935	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FORC77_RS10940	COG0596	Alpha beta hydrolase
FORC77_RS10950	COG1169	isochorismate synthase
FORC77_RS10955	COG0436	Aminotransferase
FORC77_RS10960	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
FORC77_RS10965	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FORC77_RS10980	COG1555	photosystem II stabilization
FORC77_RS10985	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FORC77_RS10990	COG0776	regulation of translation
FORC77_RS10995	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FORC77_RS11000	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FORC77_RS11015	COG4191	Histidine kinase
FORC77_RS11020	COG2204	response regulator
FORC77_RS11030	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FORC77_RS11035	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FORC77_RS11040	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FORC77_RS11045	COG3842	ATPase activity
FORC77_RS11075	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FORC77_RS11120	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FORC77_RS11125	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FORC77_RS11135	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FORC77_RS11145	COG1216	Glycosyl transferase, family 2
FORC77_RS11150	COG2986	histidine ammonia-lyase
FORC77_RS11185	COG1028	Short-chain dehydrogenase reductase Sdr
FORC77_RS11200	COG5002	protein histidine kinase activity
FORC77_RS11205	COG0745	RESPONSE REGULATOR receiver
FORC77_RS11215	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FORC77_RS11225	COG2951	lytic endotransglycosylase activity
FORC77_RS11235	COG0850	regulation of cytokinetic process
FORC77_RS11240	COG2894	cell division
FORC77_RS11245	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FORC77_RS11250	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FORC77_RS11255	COG0318	PFAM AMP-dependent synthetase and ligase
FORC77_RS11260	COG0596	Alpha beta hydrolase
FORC77_RS11275	COG1214	PFAM Peptidase M22, glycoprotease
FORC77_RS11280	COG1199	ATP-dependent helicase activity
FORC77_RS11290	COG0788	formyltetrahydrofolate deformylase activity
FORC77_RS11295	COG3102	Protein conserved in bacteria
FORC77_RS11315	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FORC77_RS11320	COG1918	ferrous iron import across plasma membrane
FORC77_RS11330	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
FORC77_RS11335	COG1121	(ABC) transporter
FORC77_RS11340	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FORC77_RS11355	COG0508	dehydrogenase complex catalyzes the overall conversion of
FORC77_RS11360	COG0567	Dehydrogenase, E1 component
FORC77_RS11370	COG1053	succinate dehydrogenase
FORC77_RS11375	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FORC77_RS11380	COG2009	succinate dehydrogenase
FORC77_RS11390	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FORC77_RS11400	COG0446	pyridine nucleotide-disulphide oxidoreductase
FORC77_RS11410	COG0251	oxidation-reduction process
FORC77_RS11415	COG2964	Protein conserved in bacteria
FORC77_RS11420	COG0033	Phosphoglucomutase
FORC77_RS11425	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
FORC77_RS11430	COG0596	Alpha beta hydrolase
FORC77_RS11440	COG0716	FMN binding
FORC77_RS11455	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FORC77_RS11460	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC77_RS11460	COG2190	(PTS) system
FORC77_RS11460	COG1263	PTS System
FORC77_RS11465	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FORC77_RS11470	COG1940	carbohydrate kinase activity
FORC77_RS11470	COG1846	Transcriptional regulator
FORC77_RS11475	COG4651	solute:proton antiporter activity
FORC77_RS11475	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FORC77_RS11480	COG0367	asparagine synthase
FORC77_RS11490	COG3104	oligopeptide transport
FORC77_RS11495	COG0840	transmembrane signaling receptor activity
FORC77_RS11500	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FORC77_RS11510	COG0326	Molecular chaperone. Has ATPase activity
FORC77_RS11515	COG3710	Transcriptional regulator
FORC77_RS11535	COG0622	Phosphoesterase
FORC77_RS11560	COG1090	epimerase
FORC77_RS11565	COG0300	oxidoreductase activity
FORC77_RS11575	COG3118	belongs to the thioredoxin family
FORC77_RS11580	COG0330	HflC and HflK could
FORC77_RS11610	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
FORC77_RS11615	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FORC77_RS11620	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC77_RS11625	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FORC77_RS11630	COG2190	(PTS) system
FORC77_RS11635	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FORC77_RS11640	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FORC77_RS11655	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FORC77_RS11660	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FORC77_RS11670	COG3951	Flagellar rod assembly protein muramidase FlgJ
FORC77_RS11670	COG1705	Flagellar rod assembly protein muramidase FlgJ
FORC77_RS11675	COG1706	bacterial-type flagellum-dependent cell motility
FORC77_RS11680	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FORC77_RS11690	COG4787	bacterial-type flagellum-dependent cell motility
FORC77_RS11695	COG1749	Flagellar hook protein flgE
FORC77_RS11710	COG1815	bacterial-type flagellum-dependent cell motility
FORC77_RS11715	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FORC77_RS11720	COG0784	Response regulator, receiver
FORC77_RS11720	COG0835	chemotaxis
FORC77_RS11740	COG3385	transposase activity
FORC77_RS11785	COG2608	mercury ion transmembrane transporter activity
FORC77_RS11785	COG2217	Heavy metal translocating P-type atpase
FORC77_RS11800	COG3735	TraB family
FORC77_RS11815	COG2840	Smr protein MutS2
FORC77_RS11820	COG1187	pseudouridine synthase activity
FORC77_RS11835	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FORC77_RS11840	COG2912	Transglutaminase-like superfamily
FORC77_RS11850	COG2890	protein-(glutamine-N5) methyltransferase activity
FORC77_RS11855	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FORC77_RS11860	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FORC77_RS11870	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FORC77_RS11875	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FORC77_RS11880	COG0193	aminoacyl-tRNA hydrolase activity
FORC77_RS11970	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FORC77_RS11980	COG1702	phosphate starvation-inducible protein PhoH
FORC77_RS11985	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FORC77_RS11990	COG4535	Mg2 and Co2 transporter CorC
FORC77_RS12000	COG2888	peptidyl-tyrosine sulfation
FORC77_RS12010	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
FORC77_RS12015	COG1466	dna polymerase III delta subunit
FORC77_RS12020	COG0799	negative regulation of ribosome biogenesis
FORC77_RS12025	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FORC77_RS12030	COG0768	penicillin binding
FORC77_RS12035	COG0772	Belongs to the SEDS family
FORC77_RS12040	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FORC77_RS12045	COG1686	Belongs to the peptidase S11 family
FORC77_RS12050	COG2921	Belongs to the UPF0250 family
FORC77_RS12055	COG0321	lipoyl(octanoyl) transferase activity
FORC77_RS12060	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FORC77_RS12070	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FORC77_RS12080	COG0366	Alpha amylase catalytic
FORC77_RS12085	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC77_RS12085	COG1263	PTS System
FORC77_RS12095	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FORC77_RS12105	COG2011	ABC-type metal ion transport system permease component
FORC77_RS12110	COG1464	Belongs to the NlpA lipoprotein family
FORC77_RS12115	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
FORC77_RS12140	COG1611	Belongs to the LOG family
FORC77_RS12145	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FORC77_RS12160	COG2363	Small membrane protein
FORC77_RS12170	COG0583	DNA-binding transcription factor activity
FORC77_RS12185	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FORC77_RS12190	COG1722	exodeoxyribonuclease VII activity
FORC77_RS12195	COG0142	geranyltranstransferase activity
FORC77_RS12200	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FORC77_RS12205	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FORC77_RS12210	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FORC77_RS12215	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FORC77_RS12220	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FORC77_RS12235	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FORC77_RS12235	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FORC77_RS12250	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FORC77_RS12260	COG1073	alpha beta
FORC77_RS12265	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
FORC77_RS12270	COG2252	PERMEase
FORC77_RS12275	COG2195	Cleaves the N-terminal amino acid of tripeptides
FORC77_RS12305	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FORC77_RS12320	COG0583	DNA-binding transcription factor activity
FORC77_RS12325	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FORC77_RS12330	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FORC77_RS12335	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
FORC77_RS12355	COG4969	Belongs to the N-Me-Phe pilin family
FORC77_RS12365	COG0484	heat shock protein binding
FORC77_RS12370	COG0443	Heat shock 70 kDa protein
FORC77_RS12400	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FORC77_RS12405	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FORC77_RS12410	COG0497	DNA recombination
FORC77_RS12415	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FORC77_RS12420	COG2914	Belongs to the UPF0125 (RnfH) family
FORC77_RS12425	COG2867	negative regulation of translational initiation
FORC77_RS12430	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FORC77_RS12480	COG0009	L-threonylcarbamoyladenylate synthase
FORC77_RS12500	COG0583	DNA-binding transcription factor activity
FORC77_RS12510	COG1115	amino acid carrier protein
FORC77_RS12515	COG1584	GPR1 FUN34 yaaH family protein
FORC77_RS12525	COG0519	Catalyzes the synthesis of GMP from XMP
FORC77_RS12525	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FORC77_RS12530	COG0517	IMP dehydrogenase activity
FORC77_RS12530	COG0516	GMP reductase activity
FORC77_RS12545	COG2199	diguanylate cyclase activity
FORC77_RS12545	COG2203	Gaf domain
FORC77_RS12555	COG1160	GTP binding
FORC77_RS12560	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FORC77_RS12565	COG2976	Protein conserved in bacteria
FORC77_RS12570	COG0124	histidyl-tRNA synthetase
FORC77_RS12575	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FORC77_RS12590	COG0105	UTP biosynthetic process
FORC77_RS12595	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FORC77_RS12600	COG2975	iron-sulfur cluster assembly
FORC77_RS12605	COG0633	Ferredoxin
FORC77_RS12610	COG0443	Heat shock 70 kDa protein
FORC77_RS12620	COG0316	Belongs to the HesB IscA family
FORC77_RS12625	COG0822	iron-sulfur transferase activity
FORC77_RS12635	COG1959	2 iron, 2 sulfur cluster binding
FORC77_RS12640	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
FORC77_RS12645	COG0483	inositol monophosphate 1-phosphatase activity
FORC77_RS12650	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FORC77_RS12655	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FORC77_RS12660	COG1862	Preprotein translocase
FORC77_RS12665	COG0343	queuine tRNA-ribosyltransferase activity
FORC77_RS12680	COG0517	IMP dehydrogenase activity
FORC77_RS12690	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FORC77_RS12695	COG0583	DNA-binding transcription factor activity
FORC77_RS12700	COG0450	alkyl hydroperoxide reductase
FORC77_RS12735	COG0704	Plays a role in the regulation of phosphate uptake
FORC77_RS12740	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FORC77_RS12745	COG0581	inorganic phosphate transmembrane transporter activity
FORC77_RS12750	COG0573	inorganic phosphate transmembrane transporter activity
FORC77_RS12755	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FORC77_RS12760	COG0248	Ppx GppA phosphatase
FORC77_RS12770	COG5002	protein histidine kinase activity
FORC77_RS12775	COG0745	RESPONSE REGULATOR receiver
FORC77_RS12785	COG0826	peptidase U32
FORC77_RS12790	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FORC77_RS12830	COG0542	response to heat
FORC77_RS12845	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FORC77_RS12850	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FORC77_RS12855	COG0077	Prephenate dehydratase
FORC77_RS12855	COG1605	Chorismate mutase
FORC77_RS12865	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
FORC77_RS12875	COG0488	(ABC) transporter
FORC77_RS12885	COG0739	heme binding
FORC77_RS12890	COG0287	Prephenate dehydrogenase
FORC77_RS12890	COG1605	Chorismate mutase
FORC77_RS12905	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FORC77_RS12925	COG1966	Carbon starvation protein
FORC77_RS12930	COG3275	phosphorelay sensor kinase activity
FORC77_RS12940	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FORC77_RS12945	COG1047	Peptidyl-prolyl cis-trans
FORC77_RS12950	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FORC77_RS12955	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FORC77_RS12960	COG0196	riboflavin kinase activity
FORC77_RS12970	COG0268	Binds directly to 16S ribosomal RNA
FORC77_RS12975	COG0640	Transcriptional regulator
FORC77_RS12980	COG0583	DNA-binding transcription factor activity
FORC77_RS12985	COG1283	sodium-dependent phosphate transmembrane transporter activity
FORC77_RS13005	COG0730	response to heat
FORC77_RS13015	COG0494	nUDIX hydrolase
FORC77_RS13020	COG3066	DNA modification
FORC77_RS13030	COG0667	Aldo Keto reductase
FORC77_RS13055	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FORC77_RS13060	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FORC77_RS13065	COG4974	Belongs to the 'phage' integrase family
FORC77_RS13080	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FORC77_RS13085	COG0513	Belongs to the DEAD box helicase family
FORC77_RS13090	COG3022	response to hydroperoxide
FORC77_RS13095	COG1115	amino acid carrier protein
FORC77_RS13110	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FORC77_RS13120	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
FORC77_RS13125	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FORC77_RS13130	COG0083	homoserine kinase activity
FORC77_RS13145	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FORC77_RS13160	COG0745	RESPONSE REGULATOR receiver
FORC77_RS13170	COG2198	Histidine kinase
FORC77_RS13170	COG5002	protein histidine kinase activity
FORC77_RS13170	COG0784	Response regulator, receiver
FORC77_RS13175	COG4251	negative regulation of phosphorylation
FORC77_RS13175	COG2203	Gaf domain
FORC77_RS13175	COG5001	Diguanylate cyclase
FORC77_RS13175	COG3706	GGDEF domain
FORC77_RS13180	COG1242	4 iron, 4 sulfur cluster binding
FORC77_RS13185	COG0070	glutamate synthase
FORC77_RS13185	COG0067	glutamate synthase
FORC77_RS13185	COG0069	glutamate synthase activity
FORC77_RS13195	COG0067	glutamate synthase
FORC77_RS13195	COG0069	glutamate synthase activity
FORC77_RS13195	COG0070	glutamate synthase
FORC77_RS13200	COG0493	'glutamate synthase
FORC77_RS13210	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FORC77_RS13220	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FORC77_RS13225	COG2860	membrane
FORC77_RS13230	COG0583	DNA-binding transcription factor activity
FORC77_RS13235	COG0730	response to heat
FORC77_RS13245	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FORC77_RS13250	COG0505	Belongs to the CarA family
FORC77_RS13260	COG0494	nUDIX hydrolase
FORC77_RS13265	COG0653	protein targeting
FORC77_RS13275	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
FORC77_RS13280	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FORC77_RS13285	COG0849	cell division
FORC77_RS13290	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FORC77_RS13295	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FORC77_RS13305	COG0772	Belongs to the SEDS family
FORC77_RS13310	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FORC77_RS13315	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FORC77_RS13320	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FORC77_RS13330	COG0768	penicillin binding
FORC77_RS13335	COG3116	cell division
FORC77_RS13340	COG0275	rRNA processing
FORC77_RS13350	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FORC77_RS13355	COG3107	peptidoglycan biosynthetic process
FORC77_RS13360	COG0792	nuclease activity
FORC77_RS13365	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FORC77_RS13370	COG2823	Periplasmic or secreted lipoprotein
FORC77_RS13375	COG2969	positive regulation of protein catabolic process
FORC77_RS13380	COG0625	glutathione transferase activity
FORC77_RS13385	COG2857	Cytochrome c1
FORC77_RS13390	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FORC77_RS13395	COG0723	plastoquinol--plastocyanin reductase activity
FORC77_RS13400	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FORC77_RS13405	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FORC77_RS13415	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FORC77_RS13420	COG3105	Protein conserved in bacteria
FORC77_RS13425	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FORC77_RS13430	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FORC77_RS13445	COG3150	esterase
FORC77_RS13455	COG3151	Protein conserved in bacteria
FORC77_RS13460	COG0494	nUDIX hydrolase
FORC77_RS13465	COG1538	Outer membrane efflux protein
FORC77_RS13485	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FORC77_RS13490	COG3025	triphosphatase activity
FORC77_RS13495	COG1392	Phosphate transport regulator
FORC77_RS13500	COG0306	phosphate transporter
FORC77_RS13505	COG4991	sh3 domain protein
FORC77_RS13510	COG3409	Peptidoglycan-binding domain 1 protein
FORC77_RS13510	COG3267	Type II secretory pathway component ExeA
FORC77_RS13515	COG0617	tRNA 3'-terminal CCA addition
FORC77_RS13520	COG1968	undecaprenyl-diphosphatase activity
FORC77_RS13525	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FORC77_RS13530	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FORC77_RS13540	COG0596	Alpha beta hydrolase
FORC77_RS13545	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FORC77_RS13550	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FORC77_RS13555	COG1610	YqeY-like protein
FORC77_RS13580	COG3550	peptidyl-serine autophosphorylation
FORC77_RS13645	COG0732	type I restriction modification DNA specificity domain
FORC77_RS13730	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FORC77_RS13735	COG2213	PTS system mannitol-specific
FORC77_RS13735	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC77_RS13745	COG3722	fumarate hydratase activity
FORC77_RS13755	COG1349	DNA-binding transcription factor activity
FORC77_RS13770	COG3706	GGDEF domain
FORC77_RS13775	COG0440	acetolactate synthase activity
FORC77_RS13780	COG0028	Belongs to the TPP enzyme family
FORC77_RS13785	COG1022	Amp-dependent synthetase and ligase
FORC77_RS13810	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FORC77_RS13815	COG0473	3-isopropylmalate dehydrogenase activity
FORC77_RS13825	COG0066	3-isopropylmalate dehydratase activity
FORC77_RS13855	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FORC77_RS13860	COG2967	ApaG domain
FORC77_RS13875	COG3610	response to peptide
FORC77_RS13880	COG2966	Psort location CytoplasmicMembrane, score
FORC77_RS13885	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FORC77_RS13890	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FORC77_RS13895	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FORC77_RS13900	COG0142	geranyltranstransferase activity
FORC77_RS13905	COG0039	L-malate dehydrogenase activity
FORC77_RS13910	COG1438	arginine binding
FORC77_RS13915	COG2358	TRAP transporter, solute receptor (TAXI family
FORC77_RS13925	COG0589	response to stress
FORC77_RS13930	COG0204	Acyl-transferase
FORC77_RS13940	COG5007	Belongs to the BolA IbaG family
FORC77_RS13950	COG2854	intermembrane phospholipid transfer
FORC77_RS13955	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FORC77_RS13960	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FORC77_RS13965	COG1127	ABC transporter
FORC77_RS13975	COG0517	IMP dehydrogenase activity
FORC77_RS13975	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FORC77_RS13980	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FORC77_RS13990	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FORC77_RS13995	COG1137	ATPase activity
FORC77_RS14005	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FORC77_RS14010	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC77_RS14015	COG1660	Displays ATPase and GTPase activities
FORC77_RS14020	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC77_RS14025	COG2239	Acts as a magnesium transporter
FORC77_RS14030	COG0312	modulator of DNA gyrase
FORC77_RS14035	COG3028	Belongs to the UPF0307 family
FORC77_RS14040	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FORC77_RS14045	COG1178	ABC-type Fe3 transport system permease component
FORC77_RS14050	COG4143	(ABC) transporter
FORC77_RS14055	COG0163	prenyltransferase activity
FORC77_RS14060	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FORC77_RS14065	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
FORC77_RS14070	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FORC77_RS14080	COG2105	PFAM AIG2 family protein
FORC77_RS14085	COG2911	Protein conserved in bacteria
FORC77_RS14090	COG0729	surface antigen
FORC77_RS14105	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
FORC77_RS14120	COG0577	efflux transmembrane transporter activity
FORC77_RS14120	COG1136	(ABC) transporter
FORC77_RS14140	COG0529	Catalyzes the synthesis of activated sulfate
FORC77_RS14145	COG3273	potassium ion transport
FORC77_RS14145	COG0471	metal ion transport
FORC77_RS14150	COG2895	sulfate adenylyltransferase (ATP) activity
FORC77_RS14155	COG0175	sulfate reduction
FORC77_RS14160	COG1648	precorrin-2 dehydrogenase activity
FORC77_RS14160	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FORC77_RS14165	COG0737	Belongs to the 5'-nucleotidase family
FORC77_RS14175	COG2153	protein acetylation
FORC77_RS14185	COG3266	domain, Protein
FORC77_RS14185	COG3061	Opacity-associated protein A
FORC77_RS14190	COG0545	Peptidyl-prolyl cis-trans isomerase
FORC77_RS14200	COG0203	ribosomal protein L17
FORC77_RS14205	COG0202	RNA polymerase activity
FORC77_RS14210	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FORC77_RS14215	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FORC77_RS14220	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FORC77_RS14225	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FORC77_RS14230	COG0201	protein transport
FORC77_RS14235	COG0200	Binds to the 23S rRNA
FORC77_RS14240	COG1841	ribosomal large subunit assembly
FORC77_RS14245	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FORC77_RS14250	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FORC77_RS14255	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FORC77_RS14260	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FORC77_RS14265	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FORC77_RS14270	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FORC77_RS14275	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FORC77_RS14280	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FORC77_RS14285	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FORC77_RS14290	COG0255	Belongs to the universal ribosomal protein uL29 family
FORC77_RS14295	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FORC77_RS14300	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FORC77_RS14310	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FORC77_RS14315	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FORC77_RS14320	COG0089	rRNA binding
FORC77_RS14325	COG0088	Forms part of the polypeptide exit tunnel
FORC77_RS14345	COG3064	Membrane
FORC77_RS14365	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FORC77_RS14390	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FORC77_RS14395	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FORC77_RS14410	COG1216	Glycosyl transferase, family 2
FORC77_RS14450	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FORC77_RS14450	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FORC77_RS14455	COG0367	asparagine synthase
FORC77_RS14490	COG1596	polysaccharide export
FORC77_RS14550	COG0859	PFAM glycosyl transferase family 9
FORC77_RS14555	COG1519	Transferase
FORC77_RS14575	COG1083	cytidylyl-transferase
FORC77_RS14595	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FORC77_RS14600	COG2089	acid synthase
FORC77_RS14610	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FORC77_RS14625	COG3083	sulfuric ester hydrolase activity
FORC77_RS14630	COG3642	lipopolysaccharide core region biosynthetic process
FORC77_RS14635	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FORC77_RS14640	COG0859	PFAM glycosyl transferase family 9
FORC77_RS14645	COG0463	Glycosyl transferase, family 2
FORC77_RS14650	COG0859	PFAM glycosyl transferase family 9
FORC77_RS14655	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FORC77_RS14675	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FORC77_RS14680	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FORC77_RS14685	COG2003	Belongs to the UPF0758 family
FORC77_RS14695	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FORC77_RS14700	COG1309	transcriptional regulator
FORC77_RS14705	COG1560	Kdo2-lipid A biosynthetic process
FORC77_RS14715	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FORC77_RS14720	COG1561	YicC-like family, N-terminal region
FORC77_RS14740	COG4608	Belongs to the ABC transporter superfamily
FORC77_RS14745	COG0444	Belongs to the ABC transporter superfamily
FORC77_RS14750	COG0747	negative chemotaxis
FORC77_RS14755	COG4239	(ABC) transporter, permease
FORC77_RS14760	COG4174	ABC transporter (Permease)
FORC77_RS14765	COG4206	TonB-dependent receptor
FORC77_RS14775	COG0811	peptide transport
FORC77_RS14780	COG0811	peptide transport
FORC77_RS14785	COG0848	biopolymer transport protein
FORC77_RS14800	COG0194	GDP metabolic process
FORC77_RS14805	COG1758	RNA polymerase activity
FORC77_RS14810	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FORC77_RS14815	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FORC77_RS14820	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FORC77_RS14825	COG2233	PERMEase
FORC77_RS14840	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FORC77_RS14845	COG2183	response to ionizing radiation
FORC77_RS14855	COG0596	Alpha beta hydrolase
FORC77_RS14860	COG1040	competence protein
FORC77_RS14865	COG0316	Belongs to the HesB IscA family
FORC77_RS14865	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FORC77_RS14870	COG0494	nUDIX hydrolase
FORC77_RS14875	COG1218	3'(2'),5'-bisphosphate nucleotidase
FORC77_RS14885	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
FORC77_RS14890	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
FORC77_RS14895	COG3156	type II secretion system protein K
FORC77_RS14900	COG4795	General secretion pathway protein
FORC77_RS14905	COG2165	general secretion pathway protein
FORC77_RS14910	COG2165	general secretion pathway protein
FORC77_RS14915	COG2165	general secretion pathway protein
FORC77_RS14920	COG1459	type II secretion system
FORC77_RS14925	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FORC77_RS14935	COG3031	protein transport across the cell outer membrane
FORC77_RS14940	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FORC77_RS14945	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FORC77_RS14960	COG0456	acetyltransferase
FORC77_RS14965	COG1490	D-aminoacyl-tRNA deacylase activity
FORC77_RS14970	COG1295	ribonuclease BN
FORC77_RS14985	COG1217	gtp-binding protein TYPA
FORC77_RS14995	COG0174	glutamine synthetase
FORC77_RS15005	COG3852	Histidine kinase
FORC77_RS15015	COG5001	Diguanylate cyclase
FORC77_RS15015	COG3300	MHYT domain
FORC77_RS15030	COG3078	GTPase activator activity
FORC77_RS15050	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FORC77_RS15050	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FORC77_RS15060	COG0084	hydrolase, TatD family'
FORC77_RS15065	COG0805	protein transport
FORC77_RS15070	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FORC77_RS15075	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FORC77_RS15085	COG3165	ubiquinone biosynthetic process from chorismate
FORC77_RS15090	COG2226	methyltransferase
FORC77_RS15095	COG1322	Protein conserved in bacteria
FORC77_RS15210	COG3118	belongs to the thioredoxin family
FORC77_RS15220	COG0248	Ppx GppA phosphatase
FORC77_RS15225	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FORC77_RS15235	COG0514	ATP-dependent DNA helicase (RecQ)
FORC77_RS15240	COG2962	Rard protein
FORC77_RS15250	COG1280	lysine exporter protein (LysE YggA)
FORC77_RS15255	COG0210	DNA helicase
FORC77_RS15265	COG3220	belongs to the UPF0276 family
FORC77_RS15295	COG0006	proline dipeptidase activity
FORC77_RS15295	COG0006	proline dipeptidase activity
FORC77_RS15305	COG2022	thiamine diphosphate biosynthetic process
FORC77_RS15315	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FORC77_RS15320	COG0352	thiamine-phosphate diphosphorylase activity
FORC77_RS15330	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FORC77_RS15335	COG2132	Multicopper oxidase
FORC77_RS15380	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FORC77_RS15390	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FORC77_RS15400	COG0009	L-threonylcarbamoyladenylate synthase
FORC77_RS15405	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FORC77_RS15415	COG0551	DNA topoisomerase type I activity
FORC77_RS15420	COG2922	Belongs to the Smg family
FORC77_RS15425	COG0758	DNA mediated transformation
FORC77_RS15435	COG0242	peptide deformylase activity
FORC77_RS15440	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FORC77_RS15445	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FORC77_RS15445	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FORC77_RS15450	COG0569	domain protein
FORC77_RS15455	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FORC77_RS15460	COG1272	protein, Hemolysin III
FORC77_RS15465	COG4326	sporulation control protein
FORC77_RS15470	COG3084	Protein conserved in bacteria
FORC77_RS15480	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FORC77_RS15485	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FORC77_RS15490	COG0204	Acyl-transferase
FORC77_RS15510	COG3978	acetolactate synthase activity
FORC77_RS15515	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FORC77_RS15520	COG0129	dihydroxy-acid dehydratase activity
FORC77_RS15530	COG0583	DNA-binding transcription factor activity
FORC77_RS15535	COG2814	Major facilitator Superfamily
FORC77_RS15545	COG0765	amino acid transport
FORC77_RS15550	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FORC77_RS15555	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FORC77_RS15560	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FORC77_RS15565	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FORC77_RS15570	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FORC77_RS15575	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FORC77_RS15580	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FORC77_RS15590	COG0356	it plays a direct role in the translocation of protons across the membrane
FORC77_RS15595	COG3312	ion transport
FORC77_RS15600	COG1475	DNA binding
FORC77_RS15605	COG1192	Involved in chromosome partitioning
FORC77_RS15610	COG0357	Ribosomal RNA small subunit methyltransferase G
FORC77_RS15625	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FORC77_RS15635	COG1196	nuclear chromosome segregation
FORC77_RS15655	COG1395	domain, Protein
FORC77_RS15720	COG4974	Belongs to the 'phage' integrase family
FORC77_RS15740	COG0594	ribonuclease P activity
FORC77_RS15745	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FORC77_RS15750	COG1126	abc transporter atp-binding protein
FORC77_RS15775	COG4580	involved in the transport of maltose and maltodextrins
FORC77_RS15790	COG1472	Belongs to the glycosyl hydrolase 3 family
FORC77_RS15795	COG0534	Mate efflux family protein
FORC77_RS15805	COG1566	PFAM secretion protein HlyD family protein
FORC77_RS15850	COG0564	pseudouridine synthase activity
FORC77_RS15875	COG1609	Transcriptional regulator
FORC77_RS15885	COG1129	ABC transporter
FORC77_RS15905	COG4580	involved in the transport of maltose and maltodextrins
FORC77_RS15915	COG2211	Major facilitator Superfamily
FORC77_RS15920	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FORC77_RS15925	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FORC77_RS15930	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
FORC77_RS15940	COG3708	Transcriptional regulator
FORC77_RS15940	COG2207	Transcriptional regulator
FORC77_RS15990	COG1482	cell wall glycoprotein biosynthetic process
FORC77_RS15995	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC77_RS15995	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FORC77_RS15995	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FORC77_RS16000	COG2207	Transcriptional regulator
FORC77_RS16010	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FORC77_RS16015	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FORC77_RS16020	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FORC77_RS16030	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FORC77_RS16050	COG3383	formate dehydrogenase (NAD+) activity
FORC77_RS16060	COG0583	DNA-binding transcription factor activity
FORC77_RS16065	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FORC77_RS16070	COG0583	DNA-binding transcription factor activity
FORC77_RS16085	COG0768	penicillin binding
FORC77_RS16120	COG0583	DNA-binding transcription factor activity
FORC77_RS16135	COG0137	argininosuccinate synthase activity
FORC77_RS16145	COG1301	dicarboxylic acid transport
FORC77_RS16195	COG2175	clavaminate synthase activity
FORC77_RS16225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FORC77_RS16235	COG3706	GGDEF domain
FORC77_RS16250	COG2356	endonuclease I
FORC77_RS16265	COG1368	sulfuric ester hydrolase activity
FORC77_RS16270	COG2194	sulfuric ester hydrolase activity
FORC77_RS16275	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FORC77_RS16280	COG2205	protein histidine kinase activity
FORC77_RS16285	COG0745	RESPONSE REGULATOR receiver
FORC77_RS16300	COG4221	oxidoreductase activity
FORC77_RS16325	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FORC77_RS16330	COG0076	glutamate decarboxylase activity
FORC77_RS16335	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FORC77_RS16345	COG0561	phosphatase activity
FORC77_RS16360	COG0671	phosphoesterase, PA-phosphatase related
FORC77_RS16435	COG2814	Major facilitator Superfamily
FORC77_RS16450	COG0039	L-malate dehydrogenase activity
FORC77_RS16455	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FORC77_RS16460	COG4771	TonB-dependent receptor
FORC77_RS16480	COG0393	Putative heavy-metal-binding
FORC77_RS16495	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FORC77_RS16505	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FORC77_RS16545	COG0346	lactoylglutathione lyase activity
FORC77_RS16555	COG2211	Major facilitator Superfamily
FORC77_RS16570	COG3240	lipase activity
FORC77_RS16635	COG3040	lipid binding
FORC77_RS16670	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
FORC77_RS16680	COG2197	response regulator
FORC77_RS16690	COG2197	response regulator
FORC77_RS16700	COG2205	protein histidine kinase activity
FORC77_RS16700	COG0784	Response regulator, receiver
FORC77_RS16705	COG3111	PFAM Bacterial OB fold (BOF) protein
FORC77_RS16715	COG2274	protein secretion by the type I secretion system
FORC77_RS16725	COG1538	Outer membrane efflux protein
FORC77_RS16745	COG0668	transmembrane transport
FORC77_RS16770	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC77_RS16775	COG0793	Belongs to the peptidase S41A family
FORC77_RS16775	COG4946	Tricorn protease homolog
FORC77_RS16795	COG4720	Psort location CytoplasmicMembrane, score
FORC77_RS16800	COG1566	PFAM secretion protein HlyD family protein
FORC77_RS16825	COG0813	purine-nucleoside phosphorylase activity
FORC77_RS16830	COG3272	Protein of unknown function (DUF1722)
FORC77_RS16835	COG0789	Transcriptional regulator
FORC77_RS16840	COG0415	Belongs to the DNA photolyase family
FORC77_RS16845	COG1376	ErfK ybiS ycfS ynhG family protein
FORC77_RS16845	COG1388	LysM domain
FORC77_RS16855	COG0513	Belongs to the DEAD box helicase family
FORC77_RS16900	COG0573	inorganic phosphate transmembrane transporter activity
FORC77_RS16905	COG0581	inorganic phosphate transmembrane transporter activity
FORC77_RS16910	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FORC77_RS16915	COG3706	GGDEF domain
FORC77_RS16915	COG2203	Gaf domain
FORC77_RS16915	COG4251	negative regulation of phosphorylation
FORC77_RS16915	COG5001	Diguanylate cyclase
FORC77_RS16925	COG2304	oxidoreductase activity
FORC77_RS16945	COG0714	Associated with various cellular activities
FORC77_RS17015	COG1596	polysaccharide export
FORC77_RS17025	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FORC77_RS17030	COG3842	ATPase activity
FORC77_RS17045	COG1175	transmembrane transport
FORC77_RS17050	COG3833	ABC-type maltose transport systems, permease component
FORC77_RS17080	COG2354	Protein conserved in bacteria
FORC77_RS17100	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FORC77_RS17145	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FORC77_RS17150	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC77_RS17160	COG0848	biopolymer transport protein
FORC77_RS17165	COG0811	peptide transport
FORC77_RS17170	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
FORC77_RS17180	COG3721	Heme iron utilization protein
FORC77_RS17185	COG0748	coenzyme F420 binding
FORC77_RS17195	COG0835	chemotaxis
FORC77_RS17195	COG0784	Response regulator, receiver
FORC77_RS17200	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FORC77_RS17205	COG0589	response to stress
FORC77_RS17210	COG0366	Alpha amylase catalytic
FORC77_RS17220	COG0840	transmembrane signaling receptor activity
FORC77_RS17235	COG3314	Sporulation integral membrane protein YlbJ
FORC77_RS17255	COG0739	heme binding
FORC77_RS17265	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FORC77_RS17275	COG2084	Dehydrogenase
FORC77_RS17300	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FORC77_RS17320	COG0840	transmembrane signaling receptor activity
FORC77_RS17335	COG3706	GGDEF domain
FORC77_RS17340	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FORC77_RS17340	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FORC77_RS17345	COG1765	OsmC-like protein
FORC77_RS17370	COG1011	Hydrolase
FORC77_RS17395	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FORC77_RS17410	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FORC77_RS17420	COG1840	ABC-type Fe3 transport system, periplasmic component
FORC77_RS17430	COG3842	ATPase activity
FORC77_RS17450	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FORC77_RS17455	COG0583	DNA-binding transcription factor activity
FORC77_RS17465	COG3104	oligopeptide transport
FORC77_RS17470	COG1760	l-serine dehydratase
FORC77_RS17490	COG1686	Belongs to the peptidase S11 family
FORC77_RS17535	COG4175	Glycine betaine
FORC77_RS17540	COG3059	membrane
FORC77_RS17545	COG3385	transposase activity
FORC77_RS17555	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FORC77_RS17575	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FORC77_RS17585	COG0247	lactate metabolic process
FORC77_RS17590	COG0546	phosphoglycolate phosphatase activity
FORC77_RS17600	COG1619	proteins homologs of microcin C7 resistance protein MccF
FORC77_RS17605	COG2133	pyrroloquinoline quinone binding
FORC77_RS17615	COG1454	alcohol dehydrogenase
FORC77_RS17620	COG0443	Heat shock 70 kDa protein
FORC77_RS17625	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FORC77_RS17655	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FORC77_RS17660	COG3174	membrane
FORC77_RS17685	COG0814	amino acid
FORC77_RS17690	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FORC77_RS17715	COG2962	Rard protein
FORC77_RS17730	COG0671	phosphoesterase, PA-phosphatase related
FORC77_RS17740	COG1288	antiporter activity
FORC77_RS17755	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
FORC77_RS17770	COG2425	protein containing a von Willebrand factor type A (vWA) domain
FORC77_RS17775	COG2315	Protein conserved in bacteria
FORC77_RS17790	COG1869	D-ribose catabolic process
FORC77_RS17800	COG1172	Belongs to the binding-protein-dependent transport system permease family
FORC77_RS17805	COG1879	ABC-type sugar transport system periplasmic component
FORC77_RS17810	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FORC77_RS17815	COG1609	Transcriptional regulator
FORC77_RS17825	COG0784	Response regulator, receiver
FORC77_RS17825	COG0835	chemotaxis
FORC77_RS17835	COG0456	acetyltransferase
FORC77_RS17850	COG1366	Belongs to the anti-sigma-factor antagonist family
FORC77_RS17860	COG2172	sigma factor antagonist activity
FORC77_RS17875	COG3437	response regulator, receiver
FORC77_RS17880	COG0420	3'-5' exonuclease activity
FORC77_RS17885	COG0419	ATPase involved in DNA repair
FORC77_RS17895	COG0583	DNA-binding transcription factor activity
FORC77_RS17915	COG4964	Belongs to the GSP D family
FORC77_RS18000	COG0471	metal ion transport
FORC77_RS18005	COG3290	protein histidine kinase activity
FORC77_RS18015	COG0110	maltose O-acetyltransferase activity
FORC77_RS18035	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC77_RS18040	COG4605	iron ion homeostasis
FORC77_RS18045	COG4604	ABC transporter, ATP-binding protein
FORC77_RS18050	COG0789	Transcriptional regulator
FORC77_RS18080	COG1289	transmembrane transporter activity
FORC77_RS18085	COG0210	DNA helicase
FORC77_RS18090	COG1803	Methylglyoxal synthase
FORC77_RS18095	COG1879	ABC-type sugar transport system periplasmic component
FORC77_RS18100	COG2198	Histidine kinase
FORC77_RS18100	COG2205	protein histidine kinase activity
FORC77_RS18100	COG0784	Response regulator, receiver
FORC77_RS18120	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FORC77_RS18125	COG3005	denitrification pathway
FORC77_RS18150	COG0513	Belongs to the DEAD box helicase family
FORC77_RS18160	COG1716	ATPase activity
FORC77_RS18160	COG5001	Diguanylate cyclase
FORC77_RS18185	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FORC77_RS18200	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
FORC77_RS18205	COG0513	Belongs to the DEAD box helicase family
FORC77_RS18210	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FORC77_RS18215	COG3119	arylsulfatase activity
FORC77_RS18225	COG3119	arylsulfatase activity
FORC77_RS18230	COG0641	radical SAM
FORC77_RS18235	COG0714	Associated with various cellular activities
FORC77_RS18265	COG0583	DNA-binding transcription factor activity
FORC77_RS18270	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
FORC77_RS18280	COG0641	radical SAM
FORC77_RS18310	COG2814	Major facilitator Superfamily
FORC77_RS18330	COG0583	DNA-binding transcription factor activity
FORC77_RS18335	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FORC77_RS18375	COG1132	(ABC) transporter
FORC77_RS18400	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FORC77_RS18400	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FORC77_RS18405	COG0509	glycine decarboxylation via glycine cleavage system
FORC77_RS18410	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FORC77_RS18455	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FORC77_RS18455	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
FORC77_RS18455	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FORC77_RS18460	COG1105	Belongs to the carbohydrate kinase PfkB family
FORC77_RS18465	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC77_RS18465	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC77_RS18470	COG1609	Transcriptional regulator
FORC77_RS18495	COG0469	pyruvate kinase activity
FORC77_RS18500	COG2271	Major facilitator Superfamily
FORC77_RS18510	COG4191	Histidine kinase
FORC77_RS18520	COG1979	alcohol dehydrogenase
FORC77_RS18525	COG2207	Transcriptional regulator
FORC77_RS18540	COG2759	Belongs to the formate--tetrahydrofolate ligase family
FORC77_RS18545	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FORC77_RS18560	COG3437	response regulator, receiver
FORC77_RS18560	COG0784	Response regulator, receiver
FORC77_RS18565	COG0546	phosphoglycolate phosphatase activity
FORC77_RS18585	COG0513	Belongs to the DEAD box helicase family
FORC77_RS18600	COG3038	cytochrome b561
FORC77_RS18605	COG2353	YceI-like domain
FORC77_RS18615	COG0583	DNA-binding transcription factor activity
FORC77_RS18630	COG0737	Belongs to the 5'-nucleotidase family
FORC77_RS18635	COG0861	Integral membrane protein TerC family
FORC77_RS18665	COG2267	carboxylic ester hydrolase activity
FORC77_RS18670	COG2067	long-chain fatty acid transport protein
FORC77_RS18685	COG2050	protein possibly involved in aromatic compounds catabolism
FORC77_RS18695	COG4533	DNA binding
FORC77_RS18705	COG0366	Alpha amylase catalytic
FORC77_RS18710	COG0583	DNA-binding transcription factor activity
FORC77_RS18730	COG0484	heat shock protein binding
FORC77_RS18745	COG5001	Diguanylate cyclase
FORC77_RS18745	COG1716	ATPase activity
FORC77_RS18750	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FORC77_RS18760	COG4181	ATPase activity
FORC77_RS18765	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FORC77_RS18770	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FORC77_RS18770	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FORC77_RS18775	COG1984	allophanate hydrolase subunit 2
FORC77_RS18780	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FORC77_RS18785	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FORC77_RS18795	COG5001	Diguanylate cyclase
FORC77_RS18795	COG3447	MASE1 domain protein
FORC77_RS18795	COG5002	protein histidine kinase activity
FORC77_RS18805	COG0583	DNA-binding transcription factor activity
FORC77_RS18810	COG1042	CoA-binding domain protein
FORC77_RS18810	COG0045	succinate-CoA ligase (ADP-forming) activity
FORC77_RS18810	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC77_RS18830	COG0023	Translation Initiation Factor
FORC77_RS18845	COG3140	Belongs to the UPF0181 family
FORC77_RS18860	COG0745	RESPONSE REGULATOR receiver
FORC77_RS18870	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FORC77_RS18875	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FORC77_RS18900	COG2199	diguanylate cyclase activity
FORC77_RS18910	COG1846	Transcriptional regulator
FORC77_RS18915	COG0697	spore germination
FORC77_RS18925	COG4149	molybdate abc transporter
FORC77_RS18930	COG0725	ABC transporter, periplasmic molybdate-binding protein
FORC77_RS18950	COG0189	ligase activity
FORC77_RS18950	COG4067	protein conserved in archaea
FORC77_RS18960	COG0840	transmembrane signaling receptor activity
FORC77_RS18965	COG0602	queuosine metabolic process
FORC77_RS18970	COG1328	CTP reductase activity
FORC77_RS19025	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FORC77_RS19030	COG3118	belongs to the thioredoxin family
FORC77_RS19035	COG0477	Major facilitator Superfamily
FORC77_RS19045	COG0534	Mate efflux family protein
FORC77_RS19065	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FORC77_RS19080	COG0848	biopolymer transport protein
FORC77_RS19085	COG0811	peptide transport
FORC77_RS19090	COG0811	peptide transport
FORC77_RS19125	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FORC77_RS19130	COG0840	transmembrane signaling receptor activity
FORC77_RS19160	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FORC77_RS19170	COG2203	Gaf domain
FORC77_RS19170	COG5001	Diguanylate cyclase
FORC77_RS19170	COG3706	GGDEF domain
FORC77_RS19170	COG4251	negative regulation of phosphorylation
FORC77_RS19180	COG0010	Belongs to the arginase family
FORC77_RS19185	COG0513	Belongs to the DEAD box helicase family
FORC77_RS19195	COG0523	cobalamin synthesis protein
FORC77_RS19205	COG2203	Gaf domain
FORC77_RS19205	COG2199	diguanylate cyclase activity
FORC77_RS19220	COG2146	nitrite reductase [NAD(P)H] activity
FORC77_RS19220	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FORC77_RS19225	COG1116	anion transmembrane transporter activity
FORC77_RS19230	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FORC77_RS19235	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FORC77_RS19235	COG1116	anion transmembrane transporter activity
FORC77_RS19240	COG3707	response regulator
FORC77_RS19255	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FORC77_RS19255	COG1648	precorrin-2 dehydrogenase activity
FORC77_RS19260	COG0243	molybdopterin cofactor binding
FORC77_RS19275	COG0840	transmembrane signaling receptor activity
FORC77_RS19280	COG0840	transmembrane signaling receptor activity
FORC77_RS19295	COG2271	Major facilitator Superfamily
FORC77_RS19300	COG0584	glycerophosphoryl diester phosphodiesterase
FORC77_RS19305	COG0312	modulator of DNA gyrase
FORC77_RS19310	COG0312	modulator of DNA gyrase
FORC77_RS19320	COG3069	C4-dicarboxylate transmembrane transporter activity
FORC77_RS19325	COG1704	LemA family
FORC77_RS19330	COG0501	Belongs to the peptidase M48B family
FORC77_RS19360	COG3335	DDE superfamily endonuclease
FORC77_RS19445	COG0631	protein serine/threonine phosphatase activity
FORC77_RS19480	COG2815	serine threonine protein kinase
FORC77_RS19480	COG0515	serine threonine protein kinase
FORC77_RS19500	COG3530	Putative quorum-sensing-regulated virulence factor
FORC77_RS19520	COG2154	pterin-4-alpha-carbinolamine dehydratase
FORC77_RS19525	COG3186	Phenylalanine-4-hydroxylase
FORC77_RS19530	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FORC77_RS19555	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
FORC77_RS19565	COG4191	Histidine kinase
FORC77_RS19565	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC77_RS19570	COG0784	Response regulator, receiver
FORC77_RS19570	COG3437	response regulator, receiver
FORC77_RS19625	COG3064	Membrane
FORC77_RS19625	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
FORC77_RS19625	COG1073	alpha beta
FORC77_RS19630	COG2994	toxin metabolic process
FORC77_RS19660	COG1028	Short-chain dehydrogenase reductase Sdr
FORC77_RS19670	COG1024	Enoyl-CoA hydratase
FORC77_RS19675	COG1024	Enoyl-CoA hydratase
FORC77_RS19680	COG1960	acyl-CoA dehydrogenase activity
FORC77_RS19690	COG0183	Belongs to the thiolase family
FORC77_RS19700	COG1960	acyl-CoA dehydrogenase activity
FORC77_RS19705	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FORC77_RS19710	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FORC77_RS19730	COG1278	Cold shock
FORC77_RS19745	COG1309	transcriptional regulator
FORC77_RS19750	COG2130	NADP-dependent
FORC77_RS19770	COG2197	response regulator
FORC77_RS19775	COG3851	Histidine kinase
FORC77_RS19780	COG2271	Major facilitator Superfamily
FORC77_RS19785	COG1482	cell wall glycoprotein biosynthetic process
FORC77_RS19795	COG2199	diguanylate cyclase activity
FORC77_RS19795	COG2203	Gaf domain
FORC77_RS19805	COG3036	rescue of stalled ribosome
FORC77_RS19810	COG1278	Cold shock
FORC77_RS19840	COG0545	Peptidyl-prolyl cis-trans isomerase
FORC77_RS19845	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FORC77_RS19850	COG0840	transmembrane signaling receptor activity
FORC77_RS19870	COG2195	Cleaves the N-terminal amino acid of tripeptides
FORC77_RS19880	COG4989	oxidoreductase activity
FORC77_RS19905	COG0038	chloride channel
FORC77_RS19915	COG1914	H( )-stimulated, divalent metal cation uptake system
FORC77_RS19920	COG0302	gtp cyclohydrolase
FORC77_RS19925	COG0303	'Molybdopterin
FORC77_RS19930	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FORC77_RS19940	COG2897	thiosulfate sulfurtransferase activity
FORC77_RS19980	COG0840	transmembrane signaling receptor activity
FORC77_RS19985	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FORC77_RS19990	COG2885	chlorophyll binding
FORC77_RS19995	COG0109	protoheme IX farnesyltransferase activity
FORC77_RS20000	COG1612	heme a metabolic process
FORC77_RS20025	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
FORC77_RS20030	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FORC77_RS20035	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FORC77_RS20040	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FORC77_RS20050	COG1280	lysine exporter protein (LysE YggA)
FORC77_RS20075	COG1846	Transcriptional regulator
FORC77_RS20080	COG1764	response to oxidative stress
FORC77_RS20090	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FORC77_RS20105	COG0697	spore germination
FORC77_RS20120	COG2814	Major facilitator Superfamily
FORC77_RS20125	COG0583	DNA-binding transcription factor activity
FORC77_RS20130	COG4251	negative regulation of phosphorylation
FORC77_RS20130	COG5001	Diguanylate cyclase
FORC77_RS20130	COG3706	GGDEF domain
FORC77_RS20130	COG2203	Gaf domain
FORC77_RS20135	COG0251	oxidation-reduction process
FORC77_RS20150	COG4145	pantothenate transmembrane transporter activity
FORC77_RS20160	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
FORC77_RS20170	COG1737	Transcriptional regulator
FORC77_RS20170	COG0837	glucose binding
FORC77_RS20180	COG1131	(ABC) transporter
FORC77_RS20185	COG0842	Transport permease protein
FORC77_RS20215	COG1846	Transcriptional regulator
FORC77_RS20220	COG2514	catechol 2,3-dioxygenase activity
FORC77_RS20230	COG0513	Belongs to the DEAD box helicase family
FORC77_RS20255	COG3568	Endonuclease Exonuclease Phosphatase
FORC77_RS20270	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FORC77_RS20335	COG0741	lytic transglycosylase activity
FORC77_RS20365	COG0330	HflC and HflK could
FORC77_RS20380	COG3457	Alanine racemase
FORC77_RS20405	COG3604	Transcriptional regulator
FORC77_RS20415	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FORC77_RS20425	COG4208	sulfate ABC transporter
FORC77_RS20460	COG0628	permease
FORC77_RS20500	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FORC77_RS20510	COG1566	PFAM secretion protein HlyD family protein
FORC77_RS20545	COG0516	GMP reductase activity
FORC77_RS20555	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FORC77_RS20555	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FORC77_RS20575	COG2197	response regulator
FORC77_RS20580	COG3850	Histidine kinase
FORC77_RS20585	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FORC77_RS20595	COG0243	molybdopterin cofactor binding
FORC77_RS20605	COG3005	denitrification pathway
FORC77_RS20615	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
FORC77_RS20620	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
FORC77_RS20625	COG1737	Transcriptional regulator
FORC77_RS20630	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FORC77_RS20635	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FORC77_RS20640	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FORC77_RS20645	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FORC77_RS20650	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
FORC77_RS20655	COG1940	carbohydrate kinase activity
FORC77_RS20660	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FORC77_RS20680	COG0183	Belongs to the thiolase family
FORC77_RS20690	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FORC77_RS20695	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FORC77_RS20745	COG1879	ABC-type sugar transport system periplasmic component
FORC77_RS20755	COG2827	Endonuclease containing a URI domain
FORC77_RS20770	COG2926	Belongs to the UPF0265 family
FORC77_RS20780	COG5002	protein histidine kinase activity
FORC77_RS20780	COG2205	protein histidine kinase activity
FORC77_RS20780	COG0784	Response regulator, receiver
FORC77_RS20805	COG0583	DNA-binding transcription factor activity
FORC77_RS20810	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FORC77_RS20830	COG1522	sequence-specific DNA binding
FORC77_RS20840	COG0531	amino acid
FORC77_RS20845	COG0121	glutamine amidotransferase
FORC77_RS20860	COG2205	protein histidine kinase activity
FORC77_RS20865	COG0745	RESPONSE REGULATOR receiver
FORC77_RS20890	COG2239	Acts as a magnesium transporter
FORC77_RS20900	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FORC77_RS20905	COG0402	S-adenosylhomocysteine deaminase activity
FORC77_RS20910	COG1067	ATP-dependent peptidase activity
FORC77_RS20920	COG4172	Belongs to the ABC transporter superfamily
FORC77_RS20925	COG1505	serine-type exopeptidase activity
FORC77_RS20930	COG0583	DNA-binding transcription factor activity
FORC77_RS20935	COG1620	l-lactate permease
FORC77_RS20945	COG1139	Iron-sulfur cluster binding protein
FORC77_RS20970	COG2814	Major facilitator Superfamily
FORC77_RS21010	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FORC77_RS21025	COG3015	lipoprotein NlpE involved in copper resistance
FORC77_RS21030	COG1126	abc transporter atp-binding protein
FORC77_RS21035	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC77_RS21040	COG4215	(ABC) transporter
FORC77_RS21045	COG4160	amino acid transport
FORC77_RS21060	COG5001	Diguanylate cyclase
FORC77_RS21060	COG5002	protein histidine kinase activity
FORC77_RS21065	COG2755	lipolytic protein G-D-S-L family
FORC77_RS21075	COG0840	transmembrane signaling receptor activity
FORC77_RS21080	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC77_RS21095	COG2977	Belongs to the P-Pant transferase superfamily
FORC77_RS21110	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FORC77_RS21115	COG1028	Short-chain dehydrogenase reductase Sdr
FORC77_RS21120	COG1169	isochorismate synthase
FORC77_RS21125	COG1021	2,3-dihydroxybenzoate-AMP ligase
FORC77_RS21145	COG1021	2,3-dihydroxybenzoate-AMP ligase
FORC77_RS21155	COG4607	ABC-type enterochelin transport system periplasmic component
FORC77_RS21160	COG4774	siderophore transport
FORC77_RS21160	COG1629	transport
FORC77_RS21170	COG0189	ligase activity
FORC77_RS21175	COG0189	ligase activity
FORC77_RS21175	COG4067	protein conserved in archaea
FORC77_RS21200	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FORC77_RS21215	COG3033	Beta-eliminating lyase
FORC77_RS21220	COG0814	amino acid
FORC77_RS21225	COG0488	(ABC) transporter
FORC77_RS21240	COG1609	Transcriptional regulator
FORC77_RS21245	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC77_RS21260	COG0242	peptide deformylase activity
FORC77_RS21270	COG1253	flavin adenine dinucleotide binding
FORC77_RS21280	COG1012	belongs to the aldehyde dehydrogenase family
FORC77_RS21285	COG3284	Transcriptional regulator
FORC77_RS21295	COG1879	ABC-type sugar transport system periplasmic component
FORC77_RS21300	COG0625	glutathione transferase activity
FORC77_RS21310	COG0384	phenazine biosynthesis protein PhzF
FORC77_RS21315	COG2197	response regulator
FORC77_RS21325	COG0673	inositol 2-dehydrogenase activity
FORC77_RS21350	COG2015	COG2015, Alkyl sulfatase and related hydrolases
FORC77_RS21365	COG0583	DNA-binding transcription factor activity
FORC77_RS21370	COG2194	sulfuric ester hydrolase activity
FORC77_RS21390	COG0798	PFAM Bile acid sodium symporter
FORC77_RS21395	COG0640	Transcriptional regulator
FORC77_RS21410	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FORC77_RS21415	COG0700	Nucleoside recognition
FORC77_RS21420	COG3366	ferrous iron transmembrane transporter activity
FORC77_RS21430	COG0366	Alpha amylase catalytic
FORC77_RS21435	COG0800	Aldolase
FORC77_RS21440	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FORC77_RS21445	COG0697	spore germination
FORC77_RS21470	COG1917	Cupin 2, conserved barrel domain protein
FORC77_RS21480	COG1028	Short-chain dehydrogenase reductase Sdr
FORC77_RS21510	COG3153	acetyltransferase
FORC77_RS21510	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FORC77_RS21530	COG0668	transmembrane transport
FORC77_RS21565	COG0494	nUDIX hydrolase
FORC77_RS21570	COG1881	PFAM PEBP family protein
FORC77_RS21575	COG2207	Transcriptional regulator
FORC77_RS21580	COG3046	protein related to deoxyribodipyrimidine photolyase
FORC77_RS21605	COG2205	protein histidine kinase activity
FORC77_RS21625	COG0454	-acetyltransferase
FORC77_RS21635	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FORC77_RS21650	COG1342	Belongs to the UPF0251 family
FORC77_RS21660	COG1858	cytochrome C peroxidase
FORC77_RS21680	COG0583	DNA-binding transcription factor activity
FORC77_RS21700	COG2814	Major facilitator Superfamily
FORC77_RS21730	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FORC77_RS21740	COG0583	DNA-binding transcription factor activity
FORC77_RS21760	COG0513	Belongs to the DEAD box helicase family
FORC77_RS21795	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FORC77_RS21805	COG1357	PFAM Pentapeptide repeats (8 copies)
FORC77_RS21825	COG3437	response regulator, receiver
FORC77_RS21835	COG0579	oxidoreductase
FORC77_RS21865	COG2015	COG2015, Alkyl sulfatase and related hydrolases
FORC77_RS21880	COG2205	protein histidine kinase activity
FORC77_RS21915	COG3706	GGDEF domain
FORC77_RS21930	COG2176	DNA-directed DNA polymerase activity
FORC77_RS21935	COG1136	(ABC) transporter
FORC77_RS21935	COG0577	efflux transmembrane transporter activity
FORC77_RS21940	COG1136	(ABC) transporter
FORC77_RS21940	COG0577	efflux transmembrane transporter activity
FORC77_RS21945	COG0577	efflux transmembrane transporter activity
FORC77_RS21970	COG1120	ATPase activity
FORC77_RS21975	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FORC77_RS22005	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC77_RS22010	COG3716	PTS system mannose fructose sorbose family IID component
FORC77_RS22020	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC77_RS22025	COG2222	sugar isomerase
FORC77_RS22035	COG1349	DNA-binding transcription factor activity
FORC77_RS22045	COG1349	DNA-binding transcription factor activity
FORC77_RS22050	COG0697	spore germination
FORC77_RS22055	COG2207	Transcriptional regulator
FORC77_RS22070	COG2015	COG2015, Alkyl sulfatase and related hydrolases
FORC77_RS22095	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FORC77_RS22100	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FORC77_RS22120	COG0840	transmembrane signaling receptor activity
FORC77_RS22135	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FORC77_RS22155	COG0583	DNA-binding transcription factor activity
FORC77_RS22160	COG1486	melibiose metabolic process
FORC77_RS22170	COG1522	sequence-specific DNA binding
FORC77_RS22185	COG2258	MOSC domain
FORC77_RS22210	COG1917	Cupin 2, conserved barrel domain protein
FORC77_RS22210	COG2207	Transcriptional regulator
FORC77_RS22215	COG1335	isochorismatase
FORC77_RS22230	COG0513	Belongs to the DEAD box helicase family
FORC77_RS22240	COG2186	Transcriptional regulator
FORC77_RS22250	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FORC77_RS22260	COG0246	Mannitol dehydrogenase
FORC77_RS22265	COG1904	glucuronate isomerase
FORC77_RS22270	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FORC77_RS22275	COG0800	Aldolase
FORC77_RS22290	COG1028	Short-chain dehydrogenase reductase Sdr
FORC77_RS22295	COG2999	glutathione oxidoreductase activity
FORC77_RS22300	COG1902	pentaerythritol trinitrate reductase activity
FORC77_RS22330	COG0561	phosphatase activity
FORC77_RS22335	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
FORC77_RS22340	COG3623	hexulose-6-phosphate isomerase
FORC77_RS22355	COG1132	(ABC) transporter
FORC77_RS22360	COG5492	domain, Protein
FORC77_RS22365	COG5426	von Willebrand factor, type A
FORC77_RS22375	COG1028	Short-chain dehydrogenase reductase Sdr
FORC77_RS22385	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FORC77_RS22390	COG0659	secondary active sulfate transmembrane transporter activity
FORC77_RS22415	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FORC77_RS22420	COG0601	transmembrane transport
FORC77_RS22430	COG0747	negative chemotaxis
FORC77_RS22440	COG3119	arylsulfatase activity
FORC77_RS22445	COG0641	radical SAM
FORC77_RS22450	COG3119	arylsulfatase activity
FORC77_RS22455	COG3119	arylsulfatase activity
FORC77_RS22460	COG5492	domain, Protein
FORC77_RS22480	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FORC77_RS22510	COG0259	pyridoxamine-phosphate oxidase activity
FORC77_RS22520	COG2204	response regulator
FORC77_RS22555	COG0459	protein refolding
FORC77_RS22560	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FORC77_RS22565	COG0110	maltose O-acetyltransferase activity
FORC77_RS22580	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FORC77_RS22580	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FORC77_RS22585	COG1737	Transcriptional regulator
FORC77_RS22595	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FORC77_RS22600	COG1263	PTS System
FORC77_RS22600	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC77_RS22610	COG2199	diguanylate cyclase activity
FORC77_RS22610	COG2200	EAL domain
FORC77_RS22610	COG2203	Gaf domain
FORC77_RS22615	COG0406	alpha-ribazole phosphatase activity
FORC77_RS22630	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FORC77_RS22670	COG0840	transmembrane signaling receptor activity
FORC77_RS22675	COG2201	protein-glutamate methylesterase activity
FORC77_RS22680	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
FORC77_RS22685	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FORC77_RS22690	COG0840	transmembrane signaling receptor activity
FORC77_RS22695	COG0835	chemotaxis
FORC77_RS22710	COG0745	RESPONSE REGULATOR receiver
FORC77_RS22720	COG1444	tRNA N-acetyltransferase activity
FORC77_RS22745	COG4608	Belongs to the ABC transporter superfamily
FORC77_RS22750	COG0444	Belongs to the ABC transporter superfamily
FORC77_RS22760	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
FORC77_RS22760	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FORC77_RS22780	COG0217	transcriptional regulatory protein
FORC77_RS22790	COG0583	DNA-binding transcription factor activity
FORC77_RS22800	COG1136	(ABC) transporter
FORC77_RS22805	COG4591	ABC-type transport system involved in lipoprotein release permease component
FORC77_RS22820	COG3275	phosphorelay sensor kinase activity
FORC77_RS22840	COG0786	glutamate:sodium symporter activity
FORC77_RS22845	COG0786	glutamate:sodium symporter activity
FORC77_RS22855	COG2801	Transposase and inactivated derivatives
FORC77_RS22860	COG2963	transposase activity
FORC77_RS22865	COG0363	glucosamine-6-phosphate deaminase activity
FORC77_RS22880	COG0189	ligase activity
FORC77_RS22900	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FORC77_RS22905	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FORC77_RS22910	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FORC77_RS22935	COG1309	transcriptional regulator
FORC77_RS22955	COG3123	guanosine phosphorylase activity
FORC77_RS22960	COG1741	Belongs to the pirin family
FORC77_RS22970	COG5001	Diguanylate cyclase
FORC77_RS22975	COG3706	GGDEF domain
FORC77_RS23030	COG1982	Orn Lys Arg decarboxylase major
FORC77_RS23035	COG0531	amino acid
FORC77_RS23055	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FORC77_RS23060	COG0183	Belongs to the thiolase family
FORC77_RS23080	COG2814	Major facilitator Superfamily
FORC77_RS23080	COG0477	Major facilitator Superfamily
FORC77_RS23090	COG3962	Belongs to the TPP enzyme family
FORC77_RS23095	COG0673	inositol 2-dehydrogenase activity
FORC77_RS23100	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FORC77_RS23125	COG0673	inositol 2-dehydrogenase activity
FORC77_RS23130	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
FORC77_RS23135	COG1162	GTPase activity
FORC77_RS23140	COG2847	Copper chaperone PCu(A)C
FORC77_RS23145	COG1999	signal sequence binding
FORC77_RS23175	COG0058	SHG alpha-glucan phosphorylase activity
FORC77_RS23180	COG1640	4-alpha-glucanotransferase
FORC77_RS23195	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FORC77_RS23250	COG1012	belongs to the aldehyde dehydrogenase family
FORC77_RS23255	COG0625	glutathione transferase activity
FORC77_RS23260	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FORC77_RS23265	COG1283	sodium-dependent phosphate transmembrane transporter activity
FORC77_RS23270	COG0612	Peptidase, M16
FORC77_RS23280	COG0583	DNA-binding transcription factor activity
FORC77_RS23285	COG0583	DNA-binding transcription factor activity
FORC77_RS23295	COG0387	Pfam Sodium calcium exchanger
FORC77_RS23300	COG0586	Pfam SNARE associated Golgi protein
FORC77_RS23310	COG0642	Histidine kinase
FORC77_RS23320	COG2199	diguanylate cyclase activity
FORC77_RS23360	COG3842	ATPase activity
FORC77_RS23365	COG1609	Transcriptional regulator
FORC77_RS23375	COG0747	negative chemotaxis
FORC77_RS23385	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FORC77_RS23390	COG0444	Belongs to the ABC transporter superfamily
FORC77_RS23395	COG4608	Belongs to the ABC transporter superfamily
FORC77_RS23405	COG1609	Transcriptional regulator