locus-tag	class	description
VVMO6_RS00010	COG0357	Ribosomal RNA small subunit methyltransferase G
VVMO6_RS00015	COG1192	Involved in chromosome partitioning
VVMO6_RS00020	COG1475	DNA binding
VVMO6_RS00025	COG3312	ion transport
VVMO6_RS00030	COG0356	it plays a direct role in the translocation of protons across the membrane
VVMO6_RS00040	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
VVMO6_RS00045	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
VVMO6_RS00050	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
VVMO6_RS00055	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
VVMO6_RS00060	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
VVMO6_RS00065	COG0355	proton-transporting ATP synthase activity, rotational mechanism
VVMO6_RS00075	COG0765	amino acid transport
VVMO6_RS00085	COG2814	Major facilitator Superfamily
VVMO6_RS00090	COG0583	DNA-binding transcription factor activity
VVMO6_RS00100	COG0129	dihydroxy-acid dehydratase activity
VVMO6_RS00105	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
VVMO6_RS00110	COG3978	acetolactate synthase activity
VVMO6_RS00120	COG0606	chelatase, subunit chli
VVMO6_RS00130	COG0204	Acyl-transferase
VVMO6_RS00135	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
VVMO6_RS00140	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
VVMO6_RS00150	COG3084	Protein conserved in bacteria
VVMO6_RS00155	COG4326	sporulation control protein
VVMO6_RS00160	COG1272	protein, Hemolysin III
VVMO6_RS00165	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
VVMO6_RS00170	COG0569	domain protein
VVMO6_RS00175	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
VVMO6_RS00175	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
VVMO6_RS00180	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
VVMO6_RS00185	COG0242	peptide deformylase activity
VVMO6_RS00195	COG0758	DNA mediated transformation
VVMO6_RS00200	COG2922	Belongs to the Smg family
VVMO6_RS00205	COG0551	DNA topoisomerase type I activity
VVMO6_RS00215	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
VVMO6_RS00220	COG0009	L-threonylcarbamoyladenylate synthase
VVMO6_RS00240	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
VVMO6_RS00275	COG3335	DDE superfamily endonuclease
VVMO6_RS00290	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
VVMO6_RS00295	COG2960	long-chain fatty acid transporting porin activity
VVMO6_RS00300	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
VVMO6_RS00305	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VVMO6_RS00310	COG1309	transcriptional regulator
VVMO6_RS00350	COG4172	Belongs to the ABC transporter superfamily
VVMO6_RS00355	COG4166	transmembrane transport
VVMO6_RS00360	COG0601	transmembrane transport
VVMO6_RS00365	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VVMO6_RS00400	COG0515	serine threonine protein kinase
VVMO6_RS00400	COG2815	serine threonine protein kinase
VVMO6_RS00410	COG0745	RESPONSE REGULATOR receiver
VVMO6_RS00415	COG1609	Transcriptional regulator
VVMO6_RS00420	COG0129	dihydroxy-acid dehydratase activity
VVMO6_RS00425	COG3265	gluconokinase activity
VVMO6_RS00435	COG0800	Aldolase
VVMO6_RS00455	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
VVMO6_RS00460	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
VVMO6_RS00470	COG1522	sequence-specific DNA binding
VVMO6_RS00475	COG5002	protein histidine kinase activity
VVMO6_RS00475	COG5001	Diguanylate cyclase
VVMO6_RS00495	COG0589	response to stress
VVMO6_RS00500	COG1528	Iron-storage protein
VVMO6_RS00510	COG2081	HI0933 family
VVMO6_RS00520	COG2959	enzyme of heme biosynthesis
VVMO6_RS00530	COG0181	hydroxymethylbilane synthase activity
VVMO6_RS00535	COG3072	Adenylate cyclase
VVMO6_RS00540	COG1965	Belongs to the frataxin family
VVMO6_RS00550	COG0019	diaminopimelate decarboxylase activity
VVMO6_RS00555	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
VVMO6_RS00565	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
VVMO6_RS00570	COG1011	Hydrolase
VVMO6_RS00575	COG2199	diguanylate cyclase activity
VVMO6_RS00575	COG3287	FIST C domain
VVMO6_RS00575	COG2200	EAL domain
VVMO6_RS00580	COG3148	PFAM DTW domain containing protein
VVMO6_RS00595	COG0561	phosphatase activity
VVMO6_RS00600	COG2267	carboxylic ester hydrolase activity
VVMO6_RS00605	COG1280	lysine exporter protein (LysE YggA)
VVMO6_RS00610	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
VVMO6_RS00615	COG0640	Transcriptional regulator
VVMO6_RS00620	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
VVMO6_RS00660	COG2095	MarC family integral membrane protein
VVMO6_RS00670	COG0742	ribosomal rna small subunit methyltransferase
VVMO6_RS00675	COG0552	protein localization to endoplasmic reticulum
VVMO6_RS00680	COG2884	Cell division ATP-binding protein ftsE
VVMO6_RS00685	COG2177	Part of the ABC transporter FtsEX involved in
VVMO6_RS00695	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
VVMO6_RS00705	COG1580	Controls the rotational direction of flagella during chemotaxis
VVMO6_RS00725	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
VVMO6_RS00735	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
VVMO6_RS00750	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
VVMO6_RS00755	COG4206	TonB-dependent receptor
VVMO6_RS00805	COG3335	DDE superfamily endonuclease
VVMO6_RS00815	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
VVMO6_RS00825	COG0812	UDP-N-acetylmuramate dehydrogenase activity
VVMO6_RS00860	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
VVMO6_RS00865	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
VVMO6_RS00880	COG0081	regulation of translation
VVMO6_RS00885	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
VVMO6_RS00890	COG0222	ribosome binding
VVMO6_RS00895	COG0085	RNA polymerase activity
VVMO6_RS00900	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
VVMO6_RS00905	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
VVMO6_RS00925	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
VVMO6_RS00930	COG1573	uracil-dna glycosylase
VVMO6_RS00935	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
VVMO6_RS00940	COG3068	Protein conserved in bacteria
VVMO6_RS00945	COG1253	flavin adenine dinucleotide binding
VVMO6_RS00960	COG0151	Belongs to the GarS family
VVMO6_RS00965	COG0138	bifunctional purine biosynthesis protein purh
VVMO6_RS00970	COG0789	Transcriptional regulator
VVMO6_RS00975	COG0840	transmembrane signaling receptor activity
VVMO6_RS00980	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
VVMO6_RS00995	COG0439	Biotin carboxylase
VVMO6_RS01000	COG0511	ligase activity, forming carbon-carbon bonds
VVMO6_RS01005	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
VVMO6_RS01010	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
VVMO6_RS01025	COG2814	Major facilitator Superfamily
VVMO6_RS01030	COG2205	protein histidine kinase activity
VVMO6_RS01030	COG2198	Histidine kinase
VVMO6_RS01030	COG0784	Response regulator, receiver
VVMO6_RS01050	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
VVMO6_RS01060	COG2095	MarC family integral membrane protein
VVMO6_RS01075	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
VVMO6_RS01080	COG1027	Aspartate ammonia-lyase
VVMO6_RS01090	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
VVMO6_RS01100	COG2205	protein histidine kinase activity
VVMO6_RS01105	COG0745	RESPONSE REGULATOR receiver
VVMO6_RS01110	COG3678	ATP-independent chaperone mediated protein folding
VVMO6_RS01120	COG0205	6-phosphofructokinase activity
VVMO6_RS01125	COG0534	Mate efflux family protein
VVMO6_RS01130	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
VVMO6_RS01135	COG0459	protein refolding
VVMO6_RS01145	COG1285	pathogenesis
VVMO6_RS01150	COG1509	lysine 2,3-aminomutase activity
VVMO6_RS01155	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
VVMO6_RS01165	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
VVMO6_RS01170	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
VVMO6_RS01175	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
VVMO6_RS01180	COG1053	succinate dehydrogenase
VVMO6_RS01185	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
VVMO6_RS01205	COG4942	peptidase
VVMO6_RS01210	COG1045	serine acetyltransferase
VVMO6_RS01215	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
VVMO6_RS01220	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
VVMO6_RS01225	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
VVMO6_RS01240	COG0471	metal ion transport
VVMO6_RS01245	COG0688	phosphatidylethanolamine metabolic process
VVMO6_RS01250	COG1162	GTPase activity
VVMO6_RS01255	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
VVMO6_RS01315	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
VVMO6_RS01320	COG0802	atpase or kinase
VVMO6_RS01325	COG0860	N-Acetylmuramoyl-L-alanine amidase
VVMO6_RS01330	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
VVMO6_RS01340	COG1923	regulation of RNA biosynthetic process
VVMO6_RS01345	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
VVMO6_RS01350	COG0330	HflC and HflK could
VVMO6_RS01355	COG0330	HflC and HflK could
VVMO6_RS01360	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
VVMO6_RS01365	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
VVMO6_RS01370	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
VVMO6_RS01380	COG1959	2 iron, 2 sulfur cluster binding
VVMO6_RS01385	COG0402	S-adenosylhomocysteine deaminase activity
VVMO6_RS01390	COG0557	exoribonuclease II activity
VVMO6_RS01395	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
VVMO6_RS01425	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
VVMO6_RS01445	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
VVMO6_RS01450	COG3954	Phosphoribulokinase
VVMO6_RS01455	COG3089	Belongs to the UPF0270 family
VVMO6_RS01460	COG0429	hydrolase of the alpha beta-hydrolase fold
VVMO6_RS01470	COG0488	(ABC) transporter
VVMO6_RS01475	COG2249	NAD(P)H dehydrogenase (quinone) activity
VVMO6_RS01490	COG1047	Peptidyl-prolyl cis-trans
VVMO6_RS01500	COG2900	Belongs to the SlyX family
VVMO6_RS01510	COG0545	Peptidyl-prolyl cis-trans isomerase
VVMO6_RS01515	COG2964	Protein conserved in bacteria
VVMO6_RS01525	COG2923	Belongs to the DsrF TusC family
VVMO6_RS01530	COG2168	tRNA wobble position uridine thiolation
VVMO6_RS01535	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
VVMO6_RS01540	COG0049	tRNA binding
VVMO6_RS01545	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
VVMO6_RS01555	COG2906	2 iron, 2 sulfur cluster binding
VVMO6_RS01565	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
VVMO6_RS01570	COG0149	triose-phosphate isomerase activity
VVMO6_RS01595	COG1494	fructose-1,6-bisphosphatase
VVMO6_RS01600	COG3074	FtsZ-dependent cytokinesis
VVMO6_RS01610	COG1575	Belongs to the MenA family. Type 1 subfamily
VVMO6_RS01615	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
VVMO6_RS01620	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
VVMO6_RS01630	COG1609	Transcriptional regulator
VVMO6_RS01635	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
VVMO6_RS01640	COG0254	rRNA binding
VVMO6_RS01645	COG0281	malic enzyme
VVMO6_RS01650	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
VVMO6_RS01655	COG0626	cystathionine gamma-synthase activity
VVMO6_RS01660	COG0527	aspartate kinase activity
VVMO6_RS01660	COG0460	homoserine dehydrogenase
VVMO6_RS01665	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
VVMO6_RS01675	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
VVMO6_RS01680	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
VVMO6_RS01695	COG0137	argininosuccinate synthase activity
VVMO6_RS01700	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
VVMO6_RS01700	COG0165	Argininosuccinate lyase
VVMO6_RS01715	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
VVMO6_RS01745	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
VVMO6_RS01750	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
VVMO6_RS01760	COG0338	D12 class N6 adenine-specific DNA methyltransferase
VVMO6_RS01765	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
VVMO6_RS01770	COG0360	Binds together with S18 to 16S ribosomal RNA
VVMO6_RS01775	COG2965	DNA replication, synthesis of RNA primer
VVMO6_RS01785	COG0359	binds to the 23S rRNA
VVMO6_RS01800	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
VVMO6_RS01810	COG0432	Pfam Uncharacterised protein family UPF0047
VVMO6_RS01825	COG0735	belongs to the Fur family
VVMO6_RS01855	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
VVMO6_RS01940	COG1410	methionine synthase
VVMO6_RS01940	COG0646	methionine synthase
VVMO6_RS01945	COG0527	aspartate kinase activity
VVMO6_RS01950	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
VVMO6_RS01960	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
VVMO6_RS01980	COG2199	diguanylate cyclase activity
VVMO6_RS01980	COG2200	EAL domain
VVMO6_RS02005	COG3267	Type II secretory pathway component ExeA
VVMO6_RS02005	COG3409	Peptidoglycan-binding domain 1 protein
VVMO6_RS02015	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
VVMO6_RS02020	COG1459	type II secretion system
VVMO6_RS02030	COG2165	general secretion pathway protein
VVMO6_RS02035	COG2165	general secretion pathway protein
VVMO6_RS02065	COG1077	Cell shape determining protein MreB Mrl
VVMO6_RS02070	COG1792	Involved in formation and maintenance of cell shape
VVMO6_RS02075	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
VVMO6_RS02080	COG0424	maF-like protein
VVMO6_RS02090	COG3164	Protein of unknown function
VVMO6_RS02095	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
VVMO6_RS02100	COG0312	modulator of DNA gyrase
VVMO6_RS02105	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
VVMO6_RS02120	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
VVMO6_RS02125	COG0251	oxidation-reduction process
VVMO6_RS02130	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
VVMO6_RS02135	COG0540	Belongs to the ATCase OTCase family
VVMO6_RS02145	COG2235	arginine
VVMO6_RS02160	COG0456	acetyltransferase
VVMO6_RS02170	COG4269	membrane
VVMO6_RS02180	COG0525	valine-tRNA ligase activity
VVMO6_RS02185	COG2927	DNA polymerase III (CHI subunit)
VVMO6_RS02190	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
VVMO6_RS02195	COG0795	lipopolysaccharide-transporting ATPase activity
VVMO6_RS02200	COG0795	lipopolysaccharide-transporting ATPase activity
VVMO6_RS02215	COG0726	polysaccharide deacetylase
VVMO6_RS02220	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
VVMO6_RS02230	COG1447	Phosphotransferase system cellobiose-specific component IIA
VVMO6_RS02235	COG1486	melibiose metabolic process
VVMO6_RS02240	COG3394	polysaccharide catabolic process
VVMO6_RS02245	COG1609	Transcriptional regulator
VVMO6_RS02255	COG3437	response regulator, receiver
VVMO6_RS02360	COG0741	lytic transglycosylase activity
VVMO6_RS02365	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
VVMO6_RS02375	COG0220	tRNA (guanine-N7-)-methyltransferase activity
VVMO6_RS02380	COG2066	Belongs to the glutaminase family
VVMO6_RS02390	COG0635	Involved in the biosynthesis of porphyrin-containing compound
VVMO6_RS02395	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
VVMO6_RS02410	COG0762	integral membrane protein
VVMO6_RS02415	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
VVMO6_RS02420	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
VVMO6_RS02435	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
VVMO6_RS02440	COG1678	Uncharacterized ACR, COG1678
VVMO6_RS02450	COG1385	rRNA (uridine-N3-)-methyltransferase activity
VVMO6_RS02460	COG2356	endonuclease I
VVMO6_RS02475	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
VVMO6_RS02480	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
VVMO6_RS02495	COG0126	phosphoglycerate kinase activity
VVMO6_RS02500	COG0191	fructose-bisphosphate aldolase activity
VVMO6_RS02505	COG0668	transmembrane transport
VVMO6_RS02510	COG1279	arginine transmembrane transporter activity
VVMO6_RS02525	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
VVMO6_RS02535	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
VVMO6_RS02540	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
VVMO6_RS02545	COG3079	Belongs to the UPF0149 family
VVMO6_RS02550	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VVMO6_RS02555	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VVMO6_RS02570	COG0354	folic acid binding
VVMO6_RS02585	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
VVMO6_RS02590	COG1595	DNA-templated transcription, initiation
VVMO6_RS02605	COG3086	response to oxidative stress
VVMO6_RS02610	COG0481	GTPase activity
VVMO6_RS02620	COG0571	ribonuclease III activity
VVMO6_RS02625	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
VVMO6_RS02630	COG1381	Involved in DNA repair and RecF pathway recombination
VVMO6_RS02635	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
VVMO6_RS02655	COG5001	Diguanylate cyclase
VVMO6_RS02660	COG2205	protein histidine kinase activity
VVMO6_RS02660	COG3437	response regulator, receiver
VVMO6_RS02660	COG3850	Histidine kinase
VVMO6_RS02660	COG4999	Histidine kinase
VVMO6_RS02670	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
VVMO6_RS02675	COG3956	TIGRFAM MazG family protein
VVMO6_RS02680	COG0504	CTP synthase activity
VVMO6_RS02685	COG0148	phosphopyruvate hydratase activity
VVMO6_RS02690	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
VVMO6_RS02695	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
VVMO6_RS02700	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
VVMO6_RS02715	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
VVMO6_RS02720	COG1388	LysM domain
VVMO6_RS02720	COG4942	peptidase
VVMO6_RS02725	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
VVMO6_RS02730	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
VVMO6_RS02740	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
VVMO6_RS02750	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
VVMO6_RS02755	COG0527	aspartate kinase activity
VVMO6_RS02760	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
VVMO6_RS02805	COG3630	sodium ion export across plasma membrane
VVMO6_RS02810	COG0511	ligase activity, forming carbon-carbon bonds
VVMO6_RS02810	COG5016	pyruvate
VVMO6_RS02815	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
VVMO6_RS02825	COG1238	metal cluster binding
VVMO6_RS02830	COG0612	Peptidase, M16
VVMO6_RS02835	COG2918	glutathione biosynthetic process
VVMO6_RS02845	COG1854	S-ribosylhomocysteine lyase activity
VVMO6_RS02850	COG4536	flavin adenine dinucleotide binding
VVMO6_RS02855	COG4137	Cytochrome C assembly protein
VVMO6_RS02860	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
VVMO6_RS02865	COG0228	four-way junction DNA binding
VVMO6_RS02870	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
VVMO6_RS02875	COG0336	Belongs to the RNA methyltransferase TrmD family
VVMO6_RS02880	COG0335	large ribosomal subunit rRNA binding
VVMO6_RS02885	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
VVMO6_RS02895	COG0237	dephospho-CoA kinase activity
VVMO6_RS02905	COG1459	type II secretion system
VVMO6_RS02910	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
VVMO6_RS02925	COG3023	N-Acetylmuramoyl-L-alanine amidase
VVMO6_RS02930	COG2186	Transcriptional regulator
VVMO6_RS02935	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
VVMO6_RS02940	COG0508	dehydrogenase complex catalyzes the overall conversion of
VVMO6_RS02945	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
VVMO6_RS02960	COG0288	reversible hydration of carbon dioxide
VVMO6_RS02965	COG0659	secondary active sulfate transmembrane transporter activity
VVMO6_RS02970	COG1131	(ABC) transporter
VVMO6_RS02975	COG0842	Transport permease protein
VVMO6_RS02985	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
VVMO6_RS02990	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
VVMO6_RS03000	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
VVMO6_RS03005	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
VVMO6_RS03010	COG1489	DNA binding
VVMO6_RS03015	COG1643	Atp-dependent helicase
VVMO6_RS03020	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
VVMO6_RS03025	COG1752	Esterase of the alpha-beta hydrolase superfamily
VVMO6_RS03030	COG1049	propionate catabolic process, 2-methylcitrate cycle
VVMO6_RS03035	COG1929	Belongs to the glycerate kinase type-1 family
VVMO6_RS03040	COG2610	gluconate transmembrane transporter activity
VVMO6_RS03045	COG3835	regulator
VVMO6_RS03050	COG3112	Uncharacterised protein family (UPF0231)
VVMO6_RS03055	COG0347	Belongs to the P(II) protein family
VVMO6_RS03060	COG0004	ammonium transporteR
VVMO6_RS03065	COG1840	ABC-type Fe3 transport system, periplasmic component
VVMO6_RS03080	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
VVMO6_RS03095	COG2971	BadF BadG BcrA BcrD
VVMO6_RS03105	COG4608	Belongs to the ABC transporter superfamily
VVMO6_RS03110	COG0444	Belongs to the ABC transporter superfamily
VVMO6_RS03115	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VVMO6_RS03120	COG0601	transmembrane transport
VVMO6_RS03130	COG0784	Response regulator, receiver
VVMO6_RS03130	COG2205	protein histidine kinase activity
VVMO6_RS03135	COG2813	Specifically methylates the guanine in position
VVMO6_RS03140	COG0628	permease
VVMO6_RS03150	COG0316	Belongs to the HesB IscA family
VVMO6_RS03165	COG0739	heme binding
VVMO6_RS03170	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
VVMO6_RS03175	COG2832	Protein of unknown function (DUF454)
VVMO6_RS03180	COG2027	D-alanyl-D-alanine carboxypeptidase
VVMO6_RS03200	COG1534	Rna-binding protein
VVMO6_RS03205	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
VVMO6_RS03210	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
VVMO6_RS03215	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
VVMO6_RS03220	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
VVMO6_RS03225	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
VVMO6_RS03240	COG0779	Required for maturation of 30S ribosomal subunits
VVMO6_RS03245	COG0195	Participates in both transcription termination and antitermination
VVMO6_RS03255	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
VVMO6_RS03260	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
VVMO6_RS03265	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
VVMO6_RS03295	COG1185	polyribonucleotide nucleotidyltransferase activity
VVMO6_RS03310	COG0534	Mate efflux family protein
VVMO6_RS03315	COG0826	peptidase U32
VVMO6_RS03320	COG0826	peptidase U32
VVMO6_RS03330	COG3154	lipid carrier protein
VVMO6_RS03335	COG3153	acetyltransferase
VVMO6_RS03345	COG0456	acetyltransferase
VVMO6_RS03355	COG3706	GGDEF domain
VVMO6_RS03365	COG0084	hydrolase, TatD family'
VVMO6_RS03370	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
VVMO6_RS03375	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
VVMO6_RS03380	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
VVMO6_RS03385	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
VVMO6_RS03390	COG0813	purine-nucleoside phosphorylase activity
VVMO6_RS03400	COG0560	Phosphoserine phosphatase
VVMO6_RS03410	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
VVMO6_RS03430	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
VVMO6_RS03435	COG0583	DNA-binding transcription factor activity
VVMO6_RS03445	COG1022	Amp-dependent synthetase and ligase
VVMO6_RS03480	COG4964	Belongs to the GSP D family
VVMO6_RS03530	COG2059	Chromate
VVMO6_RS03535	COG0583	DNA-binding transcription factor activity
VVMO6_RS03545	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
VVMO6_RS03545	COG3408	Glycogen debranching enzyme
VVMO6_RS03550	COG0531	amino acid
VVMO6_RS03555	COG0531	amino acid
VVMO6_RS03560	COG2731	YhcH YjgK YiaL family protein
VVMO6_RS03565	COG3250	beta-galactosidase activity
VVMO6_RS03575	COG1609	Transcriptional regulator
VVMO6_RS03580	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
VVMO6_RS03590	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
VVMO6_RS03595	COG2017	converts alpha-aldose to the beta-anomer
VVMO6_RS03600	COG0840	transmembrane signaling receptor activity
VVMO6_RS03610	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
VVMO6_RS03625	COG0569	domain protein
VVMO6_RS03625	COG0189	ligase activity
VVMO6_RS03640	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
VVMO6_RS03645	COG1349	DNA-binding transcription factor activity
VVMO6_RS03650	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
VVMO6_RS03655	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
VVMO6_RS03660	COG2171	N-acyltransferase activity
VVMO6_RS03665	COG3141	response to X-ray
VVMO6_RS03680	COG3083	sulfuric ester hydrolase activity
VVMO6_RS03685	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
VVMO6_RS03690	COG1074	ATP-dependent DNA helicase activity
VVMO6_RS03695	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
VVMO6_RS03715	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
VVMO6_RS03720	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
VVMO6_RS03725	COG2166	iron-sulfur cluster assembly
VVMO6_RS03730	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
VVMO6_RS03735	COG0693	protein deglycase activity
VVMO6_RS03740	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
VVMO6_RS03745	COG3248	Nucleoside-binding outer membrane protein
VVMO6_RS03755	COG1595	DNA-templated transcription, initiation
VVMO6_RS03765	COG2211	Major facilitator Superfamily
VVMO6_RS03780	COG2813	Specifically methylates the guanine in position
VVMO6_RS03785	COG0271	Belongs to the BolA IbaG family
VVMO6_RS03790	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
VVMO6_RS03795	COG1805	sodium ion transport
VVMO6_RS03800	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
VVMO6_RS03810	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
VVMO6_RS03815	COG2871	sodium ion transport
VVMO6_RS03820	COG1477	protein flavinylation
VVMO6_RS03835	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
VVMO6_RS03840	COG0514	ATP-dependent DNA helicase (RecQ)
VVMO6_RS03855	COG0733	neurotransmitter:sodium symporter activity
VVMO6_RS03880	COG1720	tRNA m6t6A37 methyltransferase activity
VVMO6_RS03885	COG0254	rRNA binding
VVMO6_RS03890	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
VVMO6_RS03910	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
VVMO6_RS03950	COG3098	single-species biofilm formation
VVMO6_RS03965	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
VVMO6_RS03970	COG0024	Methionine aminopeptidase
VVMO6_RS03975	COG0052	Belongs to the universal ribosomal protein uS2 family
VVMO6_RS03980	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
VVMO6_RS03985	COG0528	UMP kinase activity
VVMO6_RS03990	COG0233	cytoplasmic translational termination
VVMO6_RS03995	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
VVMO6_RS04000	COG0575	Belongs to the CDS family
VVMO6_RS04005	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
VVMO6_RS04010	COG0750	zinc metalloprotease
VVMO6_RS04015	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VVMO6_RS04020	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
VVMO6_RS04030	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
VVMO6_RS04035	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
VVMO6_RS04040	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
VVMO6_RS04045	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
VVMO6_RS04050	COG0587	DNA-directed DNA polymerase activity
VVMO6_RS04055	COG0825	malonyl-CoA metabolic process
VVMO6_RS04070	COG0347	Belongs to the P(II) protein family
VVMO6_RS04075	COG3021	interspecies interaction between organisms
VVMO6_RS04085	COG0741	lytic transglycosylase activity
VVMO6_RS04085	COG1388	LysM domain
VVMO6_RS04090	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
VVMO6_RS04095	COG2226	methyltransferase
VVMO6_RS04100	COG0328	RNA-DNA hybrid ribonuclease activity
VVMO6_RS04115	COG2249	NAD(P)H dehydrogenase (quinone) activity
VVMO6_RS04140	COG1960	acyl-CoA dehydrogenase activity
VVMO6_RS04150	COG0121	glutamine amidotransferase
VVMO6_RS04155	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
VVMO6_RS04160	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
VVMO6_RS04165	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
VVMO6_RS04170	COG2233	PERMEase
VVMO6_RS04190	COG1393	Belongs to the ArsC family
VVMO6_RS04195	COG4783	chaperone-mediated protein folding
VVMO6_RS04210	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
VVMO6_RS04215	COG2716	regulation of RNA biosynthetic process
VVMO6_RS04220	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
VVMO6_RS04225	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
VVMO6_RS04245	COG1393	Belongs to the ArsC family
VVMO6_RS04275	COG2837	iron assimilation
VVMO6_RS04280	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VVMO6_RS04285	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VVMO6_RS04290	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VVMO6_RS04295	COG1334	flagellar protein FlaG
VVMO6_RS04300	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
VVMO6_RS04310	COG1516	flagellar protein fliS
VVMO6_RS04330	COG1677	Flagellar hook-basal body complex protein FliE
VVMO6_RS04340	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
VVMO6_RS04390	COG1987	bacterial-type flagellum assembly
VVMO6_RS04395	COG1684	flagellar biosynthetic protein fliR
VVMO6_RS04430	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
VVMO6_RS04435	COG0784	Response regulator, receiver
VVMO6_RS04435	COG2198	Histidine kinase
VVMO6_RS04435	COG0643	Histidine kinase
VVMO6_RS04440	COG2201	protein-glutamate methylesterase activity
VVMO6_RS04445	COG1192	Involved in chromosome partitioning
VVMO6_RS04455	COG0835	chemotaxis
VVMO6_RS04465	COG4133	protoheme IX ABC transporter activity
VVMO6_RS04470	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
VVMO6_RS04475	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
VVMO6_RS04480	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
VVMO6_RS04485	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
VVMO6_RS04490	COG1138	Cytochrome C-type biogenesis protein
VVMO6_RS04495	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
VVMO6_RS04500	COG3088	subunit of a heme lyase
VVMO6_RS04500	COG4235	cytochrome complex assembly
VVMO6_RS04510	COG2853	Lipoprotein
VVMO6_RS04520	COG2067	long-chain fatty acid transport protein
VVMO6_RS04540	COG1024	Enoyl-CoA hydratase
VVMO6_RS04540	COG1250	3-hydroxyacyl-CoA dehydrogenase
VVMO6_RS04545	COG1025	Belongs to the peptidase M16 family
VVMO6_RS04555	COG2062	phosphohistidine phosphatase, SixA
VVMO6_RS04560	COG2840	Smr protein MutS2
VVMO6_RS04565	COG2890	protein-(glutamine-N5) methyltransferase activity
VVMO6_RS04570	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
VVMO6_RS04575	COG2860	membrane
VVMO6_RS04580	COG3101	peptidyl-lysine hydroxylation
VVMO6_RS04590	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
VVMO6_RS04590	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
VVMO6_RS04595	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
VVMO6_RS04605	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
VVMO6_RS04615	COG0101	tRNA pseudouridine synthase activity
VVMO6_RS04620	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
VVMO6_RS04625	COG0285	dihydrofolate synthase activity
VVMO6_RS04630	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
VVMO6_RS04635	COG1286	toxin biosynthetic process
VVMO6_RS04640	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
VVMO6_RS04645	COG0583	DNA-binding transcription factor activity
VVMO6_RS04650	COG0745	RESPONSE REGULATOR receiver
VVMO6_RS04660	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
VVMO6_RS04670	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
VVMO6_RS04675	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
VVMO6_RS04690	COG2205	protein histidine kinase activity
VVMO6_RS04695	COG0745	RESPONSE REGULATOR receiver
VVMO6_RS04710	COG2983	Belongs to the UPF0260 family
VVMO6_RS04720	COG0346	lactoylglutathione lyase activity
VVMO6_RS04730	COG1785	Belongs to the alkaline phosphatase family
VVMO6_RS04745	COG2226	methyltransferase
VVMO6_RS04750	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
VVMO6_RS04785	COG0732	type I restriction modification DNA specificity domain
VVMO6_RS04840	COG0232	Belongs to the dGTPase family. Type 2 subfamily
VVMO6_RS04845	COG1396	sequence-specific DNA binding
VVMO6_RS04850	COG3550	peptidyl-serine autophosphorylation
VVMO6_RS04860	COG2239	Acts as a magnesium transporter
VVMO6_RS04865	COG2203	Gaf domain
VVMO6_RS04865	COG2199	diguanylate cyclase activity
VVMO6_RS04885	COG3710	Transcriptional regulator
VVMO6_RS04890	COG0531	amino acid
VVMO6_RS04895	COG1982	Orn Lys Arg decarboxylase major
VVMO6_RS04900	COG3706	GGDEF domain
VVMO6_RS04905	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
VVMO6_RS04905	COG0617	tRNA 3'-terminal CCA addition
VVMO6_RS04905	COG0517	IMP dehydrogenase activity
VVMO6_RS04930	COG0537	adenosine 5'-monophosphoramidase activity
VVMO6_RS04960	COG1252	NADH dehydrogenase
VVMO6_RS04975	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
VVMO6_RS04985	COG4591	ABC-type transport system involved in lipoprotein release permease component
VVMO6_RS04990	COG1136	(ABC) transporter
VVMO6_RS04995	COG4591	ABC-type transport system involved in lipoprotein release permease component
VVMO6_RS05005	COG2333	competence protein COMEC
VVMO6_RS05005	COG0658	competence protein
VVMO6_RS05015	COG1663	tetraacyldisaccharide 4'-kinase activity
VVMO6_RS05020	COG2835	tetraacyldisaccharide 4'-kinase activity
VVMO6_RS05025	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
VVMO6_RS05030	COG2199	diguanylate cyclase activity
VVMO6_RS05035	COG2719	SpoVR family
VVMO6_RS05040	COG2718	Belongs to the UPF0229 family
VVMO6_RS05045	COG2766	serine protein kinase
VVMO6_RS05050	COG3013	Belongs to the UPF0304 family
VVMO6_RS05060	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
VVMO6_RS05075	COG1882	Formate acetyltransferase
VVMO6_RS05115	COG0708	Exodeoxyribonuclease III
VVMO6_RS05120	COG0840	transmembrane signaling receptor activity
VVMO6_RS05130	COG3923	Primosomal replication protein n
VVMO6_RS05140	COG1199	ATP-dependent helicase activity
VVMO6_RS05145	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
VVMO6_RS05165	COG1278	Cold shock
VVMO6_RS05170	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
VVMO6_RS05175	COG0542	response to heat
VVMO6_RS05180	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
VVMO6_RS05200	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
VVMO6_RS05210	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
VVMO6_RS05215	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
VVMO6_RS05220	COG0297	glycogen (starch) synthase activity
VVMO6_RS05240	COG3070	regulator of competence-specific genes
VVMO6_RS05245	COG1609	Transcriptional regulator
VVMO6_RS05250	COG3381	protein complex oligomerization
VVMO6_RS05255	COG0745	RESPONSE REGULATOR receiver
VVMO6_RS05260	COG1434	Gram-negative-bacterium-type cell wall biogenesis
VVMO6_RS05265	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
VVMO6_RS05270	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
VVMO6_RS05275	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
VVMO6_RS05310	COG4067	protein conserved in archaea
VVMO6_RS05310	COG0189	ligase activity
VVMO6_RS05315	COG0500	methyltransferase
VVMO6_RS05320	COG4106	trans-aconitate 2-methyltransferase activity
VVMO6_RS05335	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
VVMO6_RS05340	COG0840	transmembrane signaling receptor activity
VVMO6_RS05345	COG0632	four-way junction helicase activity
VVMO6_RS05350	COG2255	four-way junction helicase activity
VVMO6_RS05355	COG1271	oxidase subunit
VVMO6_RS05360	COG1294	oxidase, subunit
VVMO6_RS05375	COG0824	Thioesterase
VVMO6_RS05380	COG0811	peptide transport
VVMO6_RS05395	COG0823	Involved in the tonB-independent uptake of proteins
VVMO6_RS05400	COG2885	chlorophyll binding
VVMO6_RS05405	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
VVMO6_RS05410	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
VVMO6_RS05420	COG3766	membrane
VVMO6_RS05430	COG0754	glutathionylspermidine amidase activity
VVMO6_RS05440	COG2205	protein histidine kinase activity
VVMO6_RS05440	COG0784	Response regulator, receiver
VVMO6_RS05520	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
VVMO6_RS05535	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
VVMO6_RS05540	COG0840	transmembrane signaling receptor activity
VVMO6_RS05545	COG1349	DNA-binding transcription factor activity
VVMO6_RS05550	COG0738	Major facilitator superfamily
VVMO6_RS05555	COG2407	Converts the aldose L-fucose into the corresponding ketose L-fuculose
VVMO6_RS05560	COG1070	Carbohydrate kinase
VVMO6_RS05565	COG4154	Belongs to the RbsD FucU family
VVMO6_RS05570	COG0235	Class ii aldolase
VVMO6_RS05575	COG1454	alcohol dehydrogenase
VVMO6_RS05580	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
VVMO6_RS05585	COG0861	Integral membrane protein TerC family
VVMO6_RS05600	COG2207	Transcriptional regulator
VVMO6_RS05620	COG1032	radical SAM domain protein
VVMO6_RS05645	COG0583	DNA-binding transcription factor activity
VVMO6_RS05655	COG0857	belongs to the CobB CobQ family
VVMO6_RS05655	COG0280	phosphate acetyltransferase
VVMO6_RS05660	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
VVMO6_RS05665	COG3092	negative regulation of chromosome organization
VVMO6_RS05675	COG4120	Belongs to the binding-protein-dependent transport system permease family
VVMO6_RS05685	COG0366	Alpha amylase catalytic
VVMO6_RS05700	COG0653	protein targeting
VVMO6_RS05710	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
VVMO6_RS05715	COG2186	Transcriptional regulator
VVMO6_RS05730	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
VVMO6_RS05755	COG1846	Transcriptional regulator
VVMO6_RS05760	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
VVMO6_RS05765	COG0840	transmembrane signaling receptor activity
VVMO6_RS05785	COG1448	Aminotransferase
VVMO6_RS05790	COG2770	Histidine kinase
VVMO6_RS05790	COG3437	response regulator, receiver
VVMO6_RS05805	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
VVMO6_RS05815	COG0017	Asparaginyl-tRNA synthetase
VVMO6_RS05820	COG0840	transmembrane signaling receptor activity
VVMO6_RS05825	COG0720	synthase
VVMO6_RS05835	COG2200	EAL domain
VVMO6_RS05840	COG1760	l-serine dehydratase
VVMO6_RS05845	COG0814	amino acid
VVMO6_RS05850	COG0494	nUDIX hydrolase
VVMO6_RS05860	COG0784	Response regulator, receiver
VVMO6_RS05860	COG2205	protein histidine kinase activity
VVMO6_RS05870	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
VVMO6_RS05885	COG3106	COG3106 Predicted ATPase
VVMO6_RS05890	COG3768	UPF0283 membrane protein
VVMO6_RS05895	COG3283	Transcriptional regulator of aromatic amino acids metabolism
VVMO6_RS05900	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VVMO6_RS05915	COG0471	metal ion transport
VVMO6_RS05920	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VVMO6_RS05920	COG4191	Histidine kinase
VVMO6_RS05930	COG3706	GGDEF domain
VVMO6_RS05935	COG2199	diguanylate cyclase activity
VVMO6_RS05935	COG2200	EAL domain
VVMO6_RS05950	COG5001	Diguanylate cyclase
VVMO6_RS05950	COG3300	MHYT domain
VVMO6_RS05955	COG1328	CTP reductase activity
VVMO6_RS05960	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
VVMO6_RS05965	COG0583	DNA-binding transcription factor activity
VVMO6_RS05980	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
VVMO6_RS05985	COG4667	esterase of the alpha-beta hydrolase superfamily
VVMO6_RS05995	COG1597	lipid kinase activity
VVMO6_RS06000	COG0814	amino acid
VVMO6_RS06015	COG0783	Belongs to the Dps family
VVMO6_RS06030	COG1132	(ABC) transporter
VVMO6_RS06035	COG1132	(ABC) transporter
VVMO6_RS06040	COG1115	amino acid carrier protein
VVMO6_RS06055	COG1596	polysaccharide export
VVMO6_RS06080	COG0438	transferase activity, transferring glycosyl groups
VVMO6_RS06085	COG0438	transferase activity, transferring glycosyl groups
VVMO6_RS06085	COG0297	glycogen (starch) synthase activity
VVMO6_RS06100	COG2165	general secretion pathway protein
VVMO6_RS06125	COG0443	Heat shock 70 kDa protein
VVMO6_RS06130	COG0443	Heat shock 70 kDa protein
VVMO6_RS06140	COG3706	GGDEF domain
VVMO6_RS06160	COG3713	MltA-interacting MipA family protein
VVMO6_RS06190	COG4964	Belongs to the GSP D family
VVMO6_RS06200	COG2894	cell division
VVMO6_RS06240	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
VVMO6_RS06250	COG1643	Atp-dependent helicase
VVMO6_RS06275	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
VVMO6_RS06280	COG5380	lipid catabolic process
VVMO6_RS06285	COG3279	Response regulator of the LytR AlgR family
VVMO6_RS06295	COG2814	Major facilitator Superfamily
VVMO6_RS06310	COG0840	transmembrane signaling receptor activity
VVMO6_RS06315	COG0010	Belongs to the arginase family
VVMO6_RS06320	COG1166	arginine decarboxylase activity
VVMO6_RS06385	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
VVMO6_RS06390	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
VVMO6_RS06390	COG0072	phenylalanine-tRNA ligase activity
VVMO6_RS06395	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
VVMO6_RS06410	COG0776	regulation of translation
VVMO6_RS06420	COG0500	methyltransferase
VVMO6_RS06425	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
VVMO6_RS06445	COG2885	chlorophyll binding
VVMO6_RS06460	COG0277	FAD linked oxidase domain protein
VVMO6_RS06460	COG0247	lactate metabolic process
VVMO6_RS06465	COG2020	methyltransferase activity
VVMO6_RS06470	COG5640	endopeptidase activity
VVMO6_RS06495	COG1228	amidohydrolase
VVMO6_RS06505	COG4326	sporulation control protein
VVMO6_RS06525	COG0291	Belongs to the bacterial ribosomal protein bL35 family
VVMO6_RS06610	COG4628	conserved protein (DUF2132)
VVMO6_RS06990	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VVMO6_RS06995	COG0346	lactoylglutathione lyase activity
VVMO6_RS07070	COG0384	phenazine biosynthesis protein PhzF
VVMO6_RS07120	COG0456	acetyltransferase
VVMO6_RS07120	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
VVMO6_RS07245	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VVMO6_RS07275	COG4628	conserved protein (DUF2132)
VVMO6_RS07355	COG0534	Mate efflux family protein
VVMO6_RS07360	COG0307	riboflavin synthase, alpha
VVMO6_RS07380	COG3706	GGDEF domain
VVMO6_RS07390	COG0791	NLP P60 protein
VVMO6_RS07395	COG0840	transmembrane signaling receptor activity
VVMO6_RS07405	COG3148	PFAM DTW domain containing protein
VVMO6_RS07410	COG1940	carbohydrate kinase activity
VVMO6_RS07425	COG0746	molybdenum cofactor guanylyltransferase activity
VVMO6_RS07430	COG3842	ATPase activity
VVMO6_RS07435	COG4662	Binding-protein-dependent transport system inner membrane component
VVMO6_RS07445	COG2204	response regulator
VVMO6_RS07450	COG3852	Histidine kinase
VVMO6_RS07465	COG0488	(ABC) transporter
VVMO6_RS07475	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
VVMO6_RS07505	COG3383	formate dehydrogenase (NAD+) activity
VVMO6_RS07505	COG0243	molybdopterin cofactor binding
VVMO6_RS07510	COG0437	4 iron, 4 sulfur cluster binding
VVMO6_RS07540	COG0004	ammonium transporteR
VVMO6_RS07545	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
VVMO6_RS07550	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
VVMO6_RS07560	COG1177	transmembrane transport
VVMO6_RS07565	COG1176	ABC-type spermidine putrescine transport system, permease component I
VVMO6_RS07570	COG3842	ATPase activity
VVMO6_RS07580	COG2992	FlgJ-related protein
VVMO6_RS07590	COG0037	tRNA processing
VVMO6_RS07595	COG0589	response to stress
VVMO6_RS07600	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
VVMO6_RS07615	COG2217	Heavy metal translocating P-type atpase
VVMO6_RS07625	COG2010	Cytochrome c
VVMO6_RS07640	COG3278	Belongs to the heme-copper respiratory oxidase family
VVMO6_RS07655	COG2205	protein histidine kinase activity
VVMO6_RS07655	COG0784	Response regulator, receiver
VVMO6_RS07675	COG3120	sequence-specific DNA binding
VVMO6_RS07680	COG1067	ATP-dependent peptidase activity
VVMO6_RS07685	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
VVMO6_RS07700	COG0488	(ABC) transporter
VVMO6_RS07710	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
VVMO6_RS07710	COG0116	Belongs to the methyltransferase superfamily
VVMO6_RS07725	COG2902	Dehydrogenase
VVMO6_RS07730	COG0308	aminopeptidase N
VVMO6_RS07765	COG0641	radical SAM
VVMO6_RS07845	COG4695	Portal protein
VVMO6_RS07935	COG1428	Deoxynucleoside kinase
VVMO6_RS08025	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
VVMO6_RS08030	COG0308	aminopeptidase N
VVMO6_RS08045	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
VVMO6_RS08050	COG1956	GAF domain-containing protein
VVMO6_RS08055	COG1132	(ABC) transporter
VVMO6_RS08060	COG2995	paraquat-inducible protein a
VVMO6_RS08065	COG3008	intermembrane lipid transfer
VVMO6_RS08070	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
VVMO6_RS08070	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
VVMO6_RS08075	COG2996	Protein conserved in bacteria
VVMO6_RS08090	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
VVMO6_RS08100	COG3706	GGDEF domain
VVMO6_RS08105	COG1793	dna ligase
VVMO6_RS08110	COG1366	Belongs to the anti-sigma-factor antagonist family
VVMO6_RS08140	COG2204	response regulator
VVMO6_RS08185	COG0438	transferase activity, transferring glycosyl groups
VVMO6_RS08195	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
VVMO6_RS08230	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
VVMO6_RS08235	COG0363	glucosamine-6-phosphate deaminase activity
VVMO6_RS08240	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
VVMO6_RS08245	COG4565	transcriptional regulatory protein
VVMO6_RS08250	COG3290	protein histidine kinase activity
VVMO6_RS08265	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VVMO6_RS08295	COG1115	amino acid carrier protein
VVMO6_RS08310	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
VVMO6_RS08315	COG0204	Acyl-transferase
VVMO6_RS08320	COG0348	domain, Protein
VVMO6_RS08325	COG0437	4 iron, 4 sulfur cluster binding
VVMO6_RS08335	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VVMO6_RS08340	COG4597	amino acid ABC transporter
VVMO6_RS08345	COG0765	amino acid transport
VVMO6_RS08350	COG1126	abc transporter atp-binding protein
VVMO6_RS08355	COG0670	Belongs to the BI1 family
VVMO6_RS08365	COG2920	part of a sulfur-relay system
VVMO6_RS08380	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
VVMO6_RS08405	COG3706	GGDEF domain
VVMO6_RS08410	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
VVMO6_RS08415	COG0602	queuosine metabolic process
VVMO6_RS08420	COG0561	phosphatase activity
VVMO6_RS08450	COG2828	Protein conserved in bacteria
VVMO6_RS08460	COG0372	Belongs to the citrate synthase family
VVMO6_RS08465	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
VVMO6_RS08475	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
VVMO6_RS08515	COG2197	response regulator
VVMO6_RS08525	COG0730	response to heat
VVMO6_RS08540	COG1653	transport
VVMO6_RS08545	COG1175	transmembrane transport
VVMO6_RS08550	COG0395	ABC-type sugar transport system, permease component
VVMO6_RS08555	COG3842	ATPase activity
VVMO6_RS08560	COG1349	DNA-binding transcription factor activity
VVMO6_RS08565	COG0584	glycerophosphoryl diester phosphodiesterase
VVMO6_RS08580	COG1278	Cold shock
VVMO6_RS08620	COG0625	glutathione transferase activity
VVMO6_RS08630	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
VVMO6_RS08640	COG2195	Cleaves the N-terminal amino acid of tripeptides
VVMO6_RS08655	COG3063	Type IV pilus biogenesis stability protein PilW
VVMO6_RS08670	COG1451	nucleotide metabolic process
VVMO6_RS08680	COG0583	DNA-binding transcription factor activity
VVMO6_RS08700	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
VVMO6_RS08710	COG2988	succinylglutamate desuccinylase activity
VVMO6_RS08730	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
VVMO6_RS08745	COG2925	Exonuclease
VVMO6_RS08750	COG1380	Effector of murein hydrolase LrgA
VVMO6_RS08755	COG1346	cytolysis
VVMO6_RS08765	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
VVMO6_RS08780	COG1643	Atp-dependent helicase
VVMO6_RS08785	COG0281	malic enzyme
VVMO6_RS08790	COG2949	membrane
VVMO6_RS08795	COG0471	metal ion transport
VVMO6_RS08820	COG0492	ferredoxin-NADP+ reductase activity
VVMO6_RS08825	COG4988	ABC transporter
VVMO6_RS08830	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
VVMO6_RS08835	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
VVMO6_RS08845	COG5002	protein histidine kinase activity
VVMO6_RS08845	COG5002	protein histidine kinase activity
VVMO6_RS08860	COG3070	regulator of competence-specific genes
VVMO6_RS08870	COG2431	L-lysine efflux transmembrane transporter activity
VVMO6_RS08880	COG0076	glutamate decarboxylase activity
VVMO6_RS08885	COG1737	Transcriptional regulator
VVMO6_RS08890	COG1979	alcohol dehydrogenase
VVMO6_RS08895	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
VVMO6_RS08900	COG3273	potassium ion transport
VVMO6_RS08900	COG2985	domain, Protein
VVMO6_RS08920	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
VVMO6_RS08935	COG1136	(ABC) transporter
VVMO6_RS08940	COG0702	epimerase
VVMO6_RS08955	COG2814	Major facilitator Superfamily
VVMO6_RS08965	COG1061	Type III restriction enzyme res subunit
VVMO6_RS08980	COG2205	protein histidine kinase activity
VVMO6_RS08985	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
VVMO6_RS09010	COG3313	Fe-S protein
VVMO6_RS09020	COG4134	Bacterial extracellular solute-binding protein
VVMO6_RS09025	COG4135	transport system, permease component
VVMO6_RS09030	COG4136	ATPase activity
VVMO6_RS09035	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
VVMO6_RS09040	COG3604	Transcriptional regulator
VVMO6_RS09045	COG1151	hydroxylamine reductase activity
VVMO6_RS09050	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
VVMO6_RS09060	COG0564	pseudouridine synthase activity
VVMO6_RS09070	COG0733	neurotransmitter:sodium symporter activity
VVMO6_RS09080	COG0626	cystathionine gamma-synthase activity
VVMO6_RS09085	COG2818	Glycosylase
VVMO6_RS09105	COG1983	PspC domain protein
VVMO6_RS09115	COG1842	Phage shock protein A
VVMO6_RS09120	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
VVMO6_RS09145	COG4172	Belongs to the ABC transporter superfamily
VVMO6_RS09160	COG1227	inorganic diphosphatase activity
VVMO6_RS09190	COG0243	molybdopterin cofactor binding
VVMO6_RS09195	COG3005	denitrification pathway
VVMO6_RS09200	COG4459	periplasmic nitrate reductase
VVMO6_RS09205	COG0390	transport system, permease component
VVMO6_RS09210	COG2116	formate transmembrane transporter activity
VVMO6_RS09230	COG0583	DNA-binding transcription factor activity
VVMO6_RS09235	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
VVMO6_RS09245	COG1435	thymidine kinase activity
VVMO6_RS09250	COG0215	cysteine-tRNA ligase activity
VVMO6_RS09255	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
VVMO6_RS09260	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
VVMO6_RS09265	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
VVMO6_RS09270	COG3012	SEC-C Motif Domain Protein
VVMO6_RS09290	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
VVMO6_RS09295	COG0131	Imidazoleglycerol-phosphate dehydratase
VVMO6_RS09295	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
VVMO6_RS09300	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
VVMO6_RS09310	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
VVMO6_RS09315	COG1757	Na H antiporter
VVMO6_RS09320	COG2916	Histone family protein nucleoid-structuring protein H-NS
VVMO6_RS09325	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VVMO6_RS09335	COG0482	sulfurtransferase activity
VVMO6_RS09340	COG2915	High frequency lysogenization protein hflD homolog
VVMO6_RS09345	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
VVMO6_RS09365	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
VVMO6_RS09380	COG1028	Short-chain dehydrogenase reductase Sdr
VVMO6_RS09390	COG0501	Belongs to the peptidase M48B family
VVMO6_RS09395	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
VVMO6_RS09410	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
VVMO6_RS09415	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
VVMO6_RS09425	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
VVMO6_RS09430	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
VVMO6_RS09445	COG0686	Belongs to the AlaDH PNT family
VVMO6_RS09455	COG0583	DNA-binding transcription factor activity
VVMO6_RS09485	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
VVMO6_RS09490	COG3108	Peptidase M15
VVMO6_RS09495	COG2989	Protein conserved in bacteria
VVMO6_RS09535	COG4608	Belongs to the ABC transporter superfamily
VVMO6_RS09540	COG0444	Belongs to the ABC transporter superfamily
VVMO6_RS09545	COG4166	transmembrane transport
VVMO6_RS09550	COG4239	(ABC) transporter, permease
VVMO6_RS09555	COG4174	ABC transporter (Permease)
VVMO6_RS09565	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
VVMO6_RS09570	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
VVMO6_RS09580	COG0539	negative regulation of cytoplasmic translation
VVMO6_RS09590	COG0616	signal peptide processing
VVMO6_RS09595	COG1028	Short-chain dehydrogenase reductase Sdr
VVMO6_RS09610	COG0587	DNA-directed DNA polymerase activity
VVMO6_RS09615	COG0784	Response regulator, receiver
VVMO6_RS09615	COG0835	chemotaxis
VVMO6_RS09620	COG1940	carbohydrate kinase activity
VVMO6_RS09625	COG0469	pyruvate kinase activity
VVMO6_RS09630	COG4667	esterase of the alpha-beta hydrolase superfamily
VVMO6_RS09640	COG0733	neurotransmitter:sodium symporter activity
VVMO6_RS09650	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VVMO6_RS09650	COG1263	PTS System
VVMO6_RS09655	COG0084	hydrolase, TatD family'
VVMO6_RS09665	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
VVMO6_RS09670	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
VVMO6_RS09685	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
VVMO6_RS09700	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
VVMO6_RS09705	COG0416	fatty acid biosynthetic process
VVMO6_RS09710	COG0333	Belongs to the bacterial ribosomal protein bL32 family
VVMO6_RS09715	COG1399	metal-binding, possibly nucleic acid-binding protein
VVMO6_RS09720	COG0424	maF-like protein
VVMO6_RS09730	COG1530	ribonuclease E activity
VVMO6_RS09735	COG0659	secondary active sulfate transmembrane transporter activity
VVMO6_RS09740	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
VVMO6_RS09745	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
VVMO6_RS09755	COG0572	uridine kinase
VVMO6_RS09760	COG0489	protein tyrosine kinase activity
VVMO6_RS09765	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
VVMO6_RS09765	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
VVMO6_RS09780	COG3088	subunit of a heme lyase
VVMO6_RS09780	COG4235	cytochrome complex assembly
VVMO6_RS09785	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
VVMO6_RS09790	COG1138	Cytochrome C-type biogenesis protein
VVMO6_RS09795	COG3301	Polysulphide reductase, NrfD
VVMO6_RS09800	COG0437	4 iron, 4 sulfur cluster binding
VVMO6_RS09805	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
VVMO6_RS09810	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
VVMO6_RS09835	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
VVMO6_RS09840	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
VVMO6_RS09845	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
VVMO6_RS09910	COG0322	excinuclease ABC activity
VVMO6_RS09915	COG2197	response regulator
VVMO6_RS09920	COG0417	DNA replication proofreading
VVMO6_RS09925	COG5001	Diguanylate cyclase
VVMO6_RS09935	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
VVMO6_RS09955	COG0009	L-threonylcarbamoyladenylate synthase
VVMO6_RS09960	COG0613	PHP domain protein
VVMO6_RS09970	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
VVMO6_RS09975	COG0512	Glutamine amidotransferase of anthranilate synthase
VVMO6_RS09980	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
VVMO6_RS09985	COG0135	phosphoribosylanthranilate isomerase activity
VVMO6_RS09985	COG0134	indole-3-glycerol-phosphate synthase activity
VVMO6_RS09990	COG0133	tryptophan synthase activity
VVMO6_RS10000	COG1301	dicarboxylic acid transport
VVMO6_RS10020	COG2350	Protein conserved in bacteria
VVMO6_RS10030	COG0435	Glutathione S-transferase
VVMO6_RS10040	COG0444	Belongs to the ABC transporter superfamily
VVMO6_RS10045	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VVMO6_RS10050	COG0601	transmembrane transport
VVMO6_RS10060	COG0314	molybdopterin synthase activity
VVMO6_RS10065	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
VVMO6_RS10075	COG0521	Mo-molybdopterin cofactor biosynthetic process
VVMO6_RS10085	COG0391	Required for morphogenesis under gluconeogenic growth conditions
VVMO6_RS10090	COG2198	Histidine kinase
VVMO6_RS10095	COG2204	response regulator
VVMO6_RS10100	COG0556	nucleotide-excision repair
VVMO6_RS10115	COG4657	Part of a membrane complex involved in electron transport
VVMO6_RS10120	COG2878	Part of a membrane complex involved in electron transport
VVMO6_RS10125	COG4656	Part of a membrane complex involved in electron transport
VVMO6_RS10130	COG4658	electron transport chain
VVMO6_RS10135	COG4659	FMN binding
VVMO6_RS10140	COG4660	Part of a membrane complex involved in electron transport
VVMO6_RS10145	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
VVMO6_RS10150	COG0346	lactoylglutathione lyase activity
VVMO6_RS10160	COG2885	chlorophyll binding
VVMO6_RS10170	COG2056	Na+-H+ antiporter family
VVMO6_RS10180	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
VVMO6_RS10195	COG1028	Short-chain dehydrogenase reductase Sdr
VVMO6_RS10200	COG1454	alcohol dehydrogenase
VVMO6_RS10200	COG1012	belongs to the aldehyde dehydrogenase family
VVMO6_RS10205	COG2095	MarC family integral membrane protein
VVMO6_RS10210	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
VVMO6_RS10220	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
VVMO6_RS10225	COG1757	Na H antiporter
VVMO6_RS10240	COG3081	Nucleoid-associated protein
VVMO6_RS10245	COG3082	Protein of unknown function (DUF1414)
VVMO6_RS10250	COG3083	sulfuric ester hydrolase activity
VVMO6_RS10320	COG0569	domain protein
VVMO6_RS10325	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
VVMO6_RS10330	COG2731	YhcH YjgK YiaL family protein
VVMO6_RS10335	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
VVMO6_RS10345	COG2205	protein histidine kinase activity
VVMO6_RS10345	COG0784	Response regulator, receiver
VVMO6_RS10350	COG0123	including yeast histone deacetylase and acetoin utilization protein
VVMO6_RS10355	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
VVMO6_RS10360	COG0778	Nitroreductase
VVMO6_RS10365	COG1902	pentaerythritol trinitrate reductase activity
VVMO6_RS10365	COG0446	pyridine nucleotide-disulphide oxidoreductase
VVMO6_RS10370	COG0616	signal peptide processing
VVMO6_RS10375	COG0252	asparaginase activity
VVMO6_RS10380	COG3139	Protein of unknown function (DUF1315)
VVMO6_RS10395	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
VVMO6_RS10425	COG5001	Diguanylate cyclase
VVMO6_RS10440	COG3126	Type III secretion system lipoprotein chaperone (YscW)
VVMO6_RS10445	COG1946	Acyl-CoA thioesterase
VVMO6_RS10455	COG1522	sequence-specific DNA binding
VVMO6_RS10460	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
VVMO6_RS10475	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
VVMO6_RS10480	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VVMO6_RS10525	COG0318	PFAM AMP-dependent synthetase and ligase
VVMO6_RS10535	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
VVMO6_RS10550	COG1169	isochorismate synthase
VVMO6_RS10555	COG0436	Aminotransferase
VVMO6_RS10560	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
VVMO6_RS10565	COG0232	Belongs to the dGTPase family. Type 2 subfamily
VVMO6_RS10580	COG1555	photosystem II stabilization
VVMO6_RS10585	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
VVMO6_RS10590	COG0776	regulation of translation
VVMO6_RS10595	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
VVMO6_RS10600	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
VVMO6_RS10615	COG4191	Histidine kinase
VVMO6_RS10620	COG2204	response regulator
VVMO6_RS10630	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
VVMO6_RS10635	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
VVMO6_RS10640	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
VVMO6_RS10645	COG3842	ATPase activity
VVMO6_RS10655	COG1175	transmembrane transport
VVMO6_RS10675	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
VVMO6_RS10720	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
VVMO6_RS10725	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
VVMO6_RS10735	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
VVMO6_RS10745	COG1216	Glycosyl transferase, family 2
VVMO6_RS10750	COG2986	histidine ammonia-lyase
VVMO6_RS10775	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
VVMO6_RS10785	COG1028	Short-chain dehydrogenase reductase Sdr
VVMO6_RS10800	COG5002	protein histidine kinase activity
VVMO6_RS10805	COG0745	RESPONSE REGULATOR receiver
VVMO6_RS10815	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
VVMO6_RS10825	COG2951	lytic endotransglycosylase activity
VVMO6_RS10835	COG0850	regulation of cytokinetic process
VVMO6_RS10840	COG2894	cell division
VVMO6_RS10845	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
VVMO6_RS10850	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
VVMO6_RS10855	COG0318	PFAM AMP-dependent synthetase and ligase
VVMO6_RS10860	COG0596	Alpha beta hydrolase
VVMO6_RS10875	COG1214	PFAM Peptidase M22, glycoprotease
VVMO6_RS10880	COG1199	ATP-dependent helicase activity
VVMO6_RS10890	COG0788	formyltetrahydrofolate deformylase activity
VVMO6_RS10895	COG3102	Protein conserved in bacteria
VVMO6_RS10920	COG1918	ferrous iron import across plasma membrane
VVMO6_RS10930	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
VVMO6_RS10935	COG1121	(ABC) transporter
VVMO6_RS10940	COG1108	ABC-type Mn2 Zn2 transport systems permease components
VVMO6_RS10955	COG0508	dehydrogenase complex catalyzes the overall conversion of
VVMO6_RS10960	COG0567	Dehydrogenase, E1 component
VVMO6_RS10970	COG1053	succinate dehydrogenase
VVMO6_RS10975	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
VVMO6_RS10980	COG2009	succinate dehydrogenase
VVMO6_RS10990	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
VVMO6_RS11000	COG0446	pyridine nucleotide-disulphide oxidoreductase
VVMO6_RS11010	COG0251	oxidation-reduction process
VVMO6_RS11015	COG2964	Protein conserved in bacteria
VVMO6_RS11020	COG0033	Phosphoglucomutase
VVMO6_RS11025	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
VVMO6_RS11030	COG0596	Alpha beta hydrolase
VVMO6_RS11040	COG0716	FMN binding
VVMO6_RS11055	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
VVMO6_RS11060	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VVMO6_RS11060	COG1263	PTS System
VVMO6_RS11060	COG2190	(PTS) system
VVMO6_RS11065	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
VVMO6_RS11070	COG1940	carbohydrate kinase activity
VVMO6_RS11070	COG1846	Transcriptional regulator
VVMO6_RS11075	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
VVMO6_RS11075	COG4651	solute:proton antiporter activity
VVMO6_RS11080	COG0367	asparagine synthase
VVMO6_RS11090	COG3104	oligopeptide transport
VVMO6_RS11095	COG0840	transmembrane signaling receptor activity
VVMO6_RS11100	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
VVMO6_RS11110	COG0326	Molecular chaperone. Has ATPase activity
VVMO6_RS11115	COG3710	Transcriptional regulator
VVMO6_RS11135	COG0622	Phosphoesterase
VVMO6_RS11160	COG1090	epimerase
VVMO6_RS11165	COG0300	oxidoreductase activity
VVMO6_RS11170	COG3118	belongs to the thioredoxin family
VVMO6_RS11175	COG0330	HflC and HflK could
VVMO6_RS11205	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
VVMO6_RS11210	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
VVMO6_RS11215	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
VVMO6_RS11220	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
VVMO6_RS11225	COG2190	(PTS) system
VVMO6_RS11230	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VVMO6_RS11235	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VVMO6_RS11245	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VVMO6_RS11250	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VVMO6_RS11260	COG3951	Flagellar rod assembly protein muramidase FlgJ
VVMO6_RS11260	COG1705	Flagellar rod assembly protein muramidase FlgJ
VVMO6_RS11265	COG1706	bacterial-type flagellum-dependent cell motility
VVMO6_RS11270	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
VVMO6_RS11280	COG4787	bacterial-type flagellum-dependent cell motility
VVMO6_RS11285	COG1749	Flagellar hook protein flgE
VVMO6_RS11300	COG1815	bacterial-type flagellum-dependent cell motility
VVMO6_RS11305	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
VVMO6_RS11310	COG0784	Response regulator, receiver
VVMO6_RS11310	COG0835	chemotaxis
VVMO6_RS11370	COG2217	Heavy metal translocating P-type atpase
VVMO6_RS11370	COG2608	mercury ion transmembrane transporter activity
VVMO6_RS11385	COG3735	TraB family
VVMO6_RS11400	COG2840	Smr protein MutS2
VVMO6_RS11405	COG1187	pseudouridine synthase activity
VVMO6_RS11420	COG2877	3-deoxy-8-phosphooctulonate synthase activity
VVMO6_RS11425	COG2912	Transglutaminase-like superfamily
VVMO6_RS11435	COG2890	protein-(glutamine-N5) methyltransferase activity
VVMO6_RS11440	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
VVMO6_RS11445	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
VVMO6_RS11455	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
VVMO6_RS11460	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
VVMO6_RS11465	COG0193	aminoacyl-tRNA hydrolase activity
VVMO6_RS11550	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VVMO6_RS11555	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
VVMO6_RS11560	COG1702	phosphate starvation-inducible protein PhoH
VVMO6_RS11565	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
VVMO6_RS11570	COG4535	Mg2 and Co2 transporter CorC
VVMO6_RS11575	COG0815	Transfers the fatty acyl group on membrane lipoproteins
VVMO6_RS11580	COG2888	peptidyl-tyrosine sulfation
VVMO6_RS11590	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
VVMO6_RS11595	COG1466	dna polymerase III delta subunit
VVMO6_RS11600	COG0799	negative regulation of ribosome biogenesis
VVMO6_RS11605	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
VVMO6_RS11610	COG0768	penicillin binding
VVMO6_RS11615	COG0772	Belongs to the SEDS family
VVMO6_RS11620	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
VVMO6_RS11625	COG1686	Belongs to the peptidase S11 family
VVMO6_RS11630	COG2921	Belongs to the UPF0250 family
VVMO6_RS11635	COG0321	lipoyl(octanoyl) transferase activity
VVMO6_RS11640	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
VVMO6_RS11650	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
VVMO6_RS11680	COG0366	Alpha amylase catalytic
VVMO6_RS11685	COG1263	PTS System
VVMO6_RS11685	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VVMO6_RS11695	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
VVMO6_RS11700	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
VVMO6_RS11705	COG2011	ABC-type metal ion transport system permease component
VVMO6_RS11710	COG1464	Belongs to the NlpA lipoprotein family
VVMO6_RS11715	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
VVMO6_RS11740	COG1611	Belongs to the LOG family
VVMO6_RS11745	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
VVMO6_RS11760	COG2363	Small membrane protein
VVMO6_RS11770	COG0583	DNA-binding transcription factor activity
VVMO6_RS11785	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
VVMO6_RS11790	COG1722	exodeoxyribonuclease VII activity
VVMO6_RS11795	COG0142	geranyltranstransferase activity
VVMO6_RS11800	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
VVMO6_RS11805	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
VVMO6_RS11810	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
VVMO6_RS11815	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
VVMO6_RS11820	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
VVMO6_RS11835	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
VVMO6_RS11835	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
VVMO6_RS11840	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
VVMO6_RS11850	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
VVMO6_RS11860	COG1073	alpha beta
VVMO6_RS11865	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
VVMO6_RS11870	COG2252	PERMEase
VVMO6_RS11875	COG2195	Cleaves the N-terminal amino acid of tripeptides
VVMO6_RS11905	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
VVMO6_RS11915	COG0583	DNA-binding transcription factor activity
VVMO6_RS11920	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
VVMO6_RS11925	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
VVMO6_RS11930	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
VVMO6_RS11960	COG0484	heat shock protein binding
VVMO6_RS11965	COG0443	Heat shock 70 kDa protein
VVMO6_RS11995	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
VVMO6_RS12000	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
VVMO6_RS12005	COG0497	DNA recombination
VVMO6_RS12010	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VVMO6_RS12015	COG2914	Belongs to the UPF0125 (RnfH) family
VVMO6_RS12020	COG2867	negative regulation of translational initiation
VVMO6_RS12025	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
VVMO6_RS12070	COG0009	L-threonylcarbamoyladenylate synthase
VVMO6_RS12090	COG0583	DNA-binding transcription factor activity
VVMO6_RS12100	COG1115	amino acid carrier protein
VVMO6_RS12105	COG1584	GPR1 FUN34 yaaH family protein
VVMO6_RS12115	COG0518	GMP synthase (glutamine-hydrolyzing) activity
VVMO6_RS12115	COG0519	Catalyzes the synthesis of GMP from XMP
VVMO6_RS12120	COG0516	GMP reductase activity
VVMO6_RS12120	COG0517	IMP dehydrogenase activity
VVMO6_RS12135	COG2203	Gaf domain
VVMO6_RS12135	COG2199	diguanylate cyclase activity
VVMO6_RS12145	COG1160	GTP binding
VVMO6_RS12150	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VVMO6_RS12155	COG2976	Protein conserved in bacteria
VVMO6_RS12160	COG0124	histidyl-tRNA synthetase
VVMO6_RS12165	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
VVMO6_RS12180	COG0105	UTP biosynthetic process
VVMO6_RS12185	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
VVMO6_RS12190	COG2975	iron-sulfur cluster assembly
VVMO6_RS12195	COG0633	Ferredoxin
VVMO6_RS12200	COG0443	Heat shock 70 kDa protein
VVMO6_RS12210	COG0316	Belongs to the HesB IscA family
VVMO6_RS12215	COG0822	iron-sulfur transferase activity
VVMO6_RS12225	COG1959	2 iron, 2 sulfur cluster binding
VVMO6_RS12230	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
VVMO6_RS12235	COG0483	inositol monophosphate 1-phosphatase activity
VVMO6_RS12250	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
VVMO6_RS12255	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
VVMO6_RS12260	COG1862	Preprotein translocase
VVMO6_RS12265	COG0343	queuine tRNA-ribosyltransferase activity
VVMO6_RS12270	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
VVMO6_RS12280	COG0517	IMP dehydrogenase activity
VVMO6_RS12290	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
VVMO6_RS12295	COG0583	DNA-binding transcription factor activity
VVMO6_RS12300	COG0450	alkyl hydroperoxide reductase
VVMO6_RS12335	COG0704	Plays a role in the regulation of phosphate uptake
VVMO6_RS12340	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
VVMO6_RS12345	COG0581	inorganic phosphate transmembrane transporter activity
VVMO6_RS12350	COG0573	inorganic phosphate transmembrane transporter activity
VVMO6_RS12360	COG0248	Ppx GppA phosphatase
VVMO6_RS12370	COG5002	protein histidine kinase activity
VVMO6_RS12375	COG0745	RESPONSE REGULATOR receiver
VVMO6_RS12385	COG0826	peptidase U32
VVMO6_RS12390	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
VVMO6_RS12445	COG0542	response to heat
VVMO6_RS12460	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VVMO6_RS12465	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
VVMO6_RS12470	COG1605	Chorismate mutase
VVMO6_RS12470	COG0077	Prephenate dehydratase
VVMO6_RS12480	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
VVMO6_RS12490	COG0488	(ABC) transporter
VVMO6_RS12500	COG0739	heme binding
VVMO6_RS12505	COG1605	Chorismate mutase
VVMO6_RS12505	COG0287	Prephenate dehydrogenase
VVMO6_RS12520	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
VVMO6_RS12535	COG1966	Carbon starvation protein
VVMO6_RS12540	COG3275	phosphorelay sensor kinase activity
VVMO6_RS12550	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
VVMO6_RS12555	COG1047	Peptidyl-prolyl cis-trans
VVMO6_RS12560	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
VVMO6_RS12565	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
VVMO6_RS12570	COG0196	riboflavin kinase activity
VVMO6_RS12575	COG0728	peptidoglycan biosynthetic process
VVMO6_RS12580	COG0268	Binds directly to 16S ribosomal RNA
VVMO6_RS12585	COG0640	Transcriptional regulator
VVMO6_RS12590	COG0583	DNA-binding transcription factor activity
VVMO6_RS12595	COG1283	sodium-dependent phosphate transmembrane transporter activity
VVMO6_RS12615	COG0730	response to heat
VVMO6_RS12625	COG0494	nUDIX hydrolase
VVMO6_RS12630	COG3066	DNA modification
VVMO6_RS12640	COG0667	Aldo Keto reductase
VVMO6_RS12660	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
VVMO6_RS12665	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
VVMO6_RS12670	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
VVMO6_RS12675	COG4974	Belongs to the 'phage' integrase family
VVMO6_RS12690	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
VVMO6_RS12695	COG0513	Belongs to the DEAD box helicase family
VVMO6_RS12705	COG1115	amino acid carrier protein
VVMO6_RS12720	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
VVMO6_RS12730	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
VVMO6_RS12735	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
VVMO6_RS12740	COG0083	homoserine kinase activity
VVMO6_RS12755	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
VVMO6_RS12765	COG0745	RESPONSE REGULATOR receiver
VVMO6_RS12775	COG5002	protein histidine kinase activity
VVMO6_RS12775	COG2198	Histidine kinase
VVMO6_RS12775	COG0784	Response regulator, receiver
VVMO6_RS12780	COG4251	negative regulation of phosphorylation
VVMO6_RS12780	COG5001	Diguanylate cyclase
VVMO6_RS12780	COG3706	GGDEF domain
VVMO6_RS12780	COG2203	Gaf domain
VVMO6_RS12785	COG1242	4 iron, 4 sulfur cluster binding
VVMO6_RS12790	COG0069	glutamate synthase activity
VVMO6_RS12790	COG0067	glutamate synthase
VVMO6_RS12790	COG0070	glutamate synthase
VVMO6_RS12800	COG0067	glutamate synthase
VVMO6_RS12800	COG0069	glutamate synthase activity
VVMO6_RS12800	COG0070	glutamate synthase
VVMO6_RS12805	COG0493	'glutamate synthase
VVMO6_RS12815	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
VVMO6_RS12830	COG2860	membrane
VVMO6_RS12835	COG0583	DNA-binding transcription factor activity
VVMO6_RS12840	COG0730	response to heat
VVMO6_RS12850	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
VVMO6_RS12855	COG0505	Belongs to the CarA family
VVMO6_RS12865	COG0494	nUDIX hydrolase
VVMO6_RS12870	COG0653	protein targeting
VVMO6_RS12880	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
VVMO6_RS12885	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
VVMO6_RS12890	COG0849	cell division
VVMO6_RS12895	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
VVMO6_RS12900	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
VVMO6_RS12910	COG0772	Belongs to the SEDS family
VVMO6_RS12915	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
VVMO6_RS12920	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
VVMO6_RS12925	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
VVMO6_RS12930	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
VVMO6_RS12935	COG0768	penicillin binding
VVMO6_RS12940	COG3116	cell division
VVMO6_RS12945	COG0275	rRNA processing
VVMO6_RS12950	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
VVMO6_RS12955	COG3107	peptidoglycan biosynthetic process
VVMO6_RS12960	COG0792	nuclease activity
VVMO6_RS12965	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
VVMO6_RS12970	COG2823	Periplasmic or secreted lipoprotein
VVMO6_RS12975	COG2969	positive regulation of protein catabolic process
VVMO6_RS12980	COG0625	glutathione transferase activity
VVMO6_RS12985	COG2857	Cytochrome c1
VVMO6_RS12990	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
VVMO6_RS12995	COG0723	plastoquinol--plastocyanin reductase activity
VVMO6_RS13000	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
VVMO6_RS13005	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
VVMO6_RS13010	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
VVMO6_RS13015	COG3105	Protein conserved in bacteria
VVMO6_RS13020	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
VVMO6_RS13025	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
VVMO6_RS13040	COG3150	esterase
VVMO6_RS13050	COG3151	Protein conserved in bacteria
VVMO6_RS13055	COG0494	nUDIX hydrolase
VVMO6_RS13060	COG1538	Outer membrane efflux protein
VVMO6_RS13065	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
VVMO6_RS13065	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
VVMO6_RS13070	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
VVMO6_RS13080	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
VVMO6_RS13085	COG3025	triphosphatase activity
VVMO6_RS13090	COG1392	Phosphate transport regulator
VVMO6_RS13095	COG0306	phosphate transporter
VVMO6_RS13100	COG4991	sh3 domain protein
VVMO6_RS13105	COG3409	Peptidoglycan-binding domain 1 protein
VVMO6_RS13105	COG3267	Type II secretory pathway component ExeA
VVMO6_RS13110	COG0617	tRNA 3'-terminal CCA addition
VVMO6_RS13115	COG1968	undecaprenyl-diphosphatase activity
VVMO6_RS13120	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
VVMO6_RS13125	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
VVMO6_RS13135	COG0596	Alpha beta hydrolase
VVMO6_RS13140	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
VVMO6_RS13145	COG0828	Belongs to the bacterial ribosomal protein bS21 family
VVMO6_RS13150	COG1610	YqeY-like protein
VVMO6_RS13180	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
VVMO6_RS13185	COG2213	PTS system mannitol-specific
VVMO6_RS13185	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
VVMO6_RS13195	COG3722	fumarate hydratase activity
VVMO6_RS13205	COG1349	DNA-binding transcription factor activity
VVMO6_RS13225	COG3706	GGDEF domain
VVMO6_RS13230	COG0440	acetolactate synthase activity
VVMO6_RS13235	COG0028	Belongs to the TPP enzyme family
VVMO6_RS13240	COG1022	Amp-dependent synthetase and ligase
VVMO6_RS13265	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
VVMO6_RS13270	COG0473	3-isopropylmalate dehydrogenase activity
VVMO6_RS13280	COG0066	3-isopropylmalate dehydratase activity
VVMO6_RS13310	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
VVMO6_RS13315	COG2967	ApaG domain
VVMO6_RS13330	COG3610	response to peptide
VVMO6_RS13335	COG2966	Psort location CytoplasmicMembrane, score
VVMO6_RS13345	COG0211	Belongs to the bacterial ribosomal protein bL27 family
VVMO6_RS13350	COG0261	This protein binds to 23S rRNA in the presence of protein L20
VVMO6_RS13355	COG0142	geranyltranstransferase activity
VVMO6_RS13360	COG0039	L-malate dehydrogenase activity
VVMO6_RS13365	COG1438	arginine binding
VVMO6_RS13370	COG2358	TRAP transporter, solute receptor (TAXI family
VVMO6_RS13380	COG0589	response to stress
VVMO6_RS13385	COG0204	Acyl-transferase
VVMO6_RS13390	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
VVMO6_RS13395	COG5007	Belongs to the BolA IbaG family
VVMO6_RS13405	COG2854	intermembrane phospholipid transfer
VVMO6_RS13410	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
VVMO6_RS13415	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
VVMO6_RS13420	COG1127	ABC transporter
VVMO6_RS13430	COG0517	IMP dehydrogenase activity
VVMO6_RS13430	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
VVMO6_RS13435	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
VVMO6_RS13445	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
VVMO6_RS13450	COG1137	ATPase activity
VVMO6_RS13460	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
VVMO6_RS13465	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
VVMO6_RS13470	COG1660	Displays ATPase and GTPase activities
VVMO6_RS13475	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
VVMO6_RS13480	COG2239	Acts as a magnesium transporter
VVMO6_RS13485	COG0312	modulator of DNA gyrase
VVMO6_RS13490	COG3028	Belongs to the UPF0307 family
VVMO6_RS13495	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
VVMO6_RS13500	COG1178	ABC-type Fe3 transport system permease component
VVMO6_RS13505	COG4143	(ABC) transporter
VVMO6_RS13510	COG0163	prenyltransferase activity
VVMO6_RS13515	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
VVMO6_RS13520	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
VVMO6_RS13525	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
VVMO6_RS13535	COG2105	PFAM AIG2 family protein
VVMO6_RS13540	COG2911	Protein conserved in bacteria
VVMO6_RS13545	COG0729	surface antigen
VVMO6_RS13560	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
VVMO6_RS13575	COG1136	(ABC) transporter
VVMO6_RS13575	COG0577	efflux transmembrane transporter activity
VVMO6_RS13595	COG0529	Catalyzes the synthesis of activated sulfate
VVMO6_RS13600	COG3273	potassium ion transport
VVMO6_RS13600	COG0471	metal ion transport
VVMO6_RS13605	COG2895	sulfate adenylyltransferase (ATP) activity
VVMO6_RS13610	COG0175	sulfate reduction
VVMO6_RS13615	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
VVMO6_RS13615	COG1648	precorrin-2 dehydrogenase activity
VVMO6_RS13620	COG0737	Belongs to the 5'-nucleotidase family
VVMO6_RS13630	COG2153	protein acetylation
VVMO6_RS13640	COG3061	Opacity-associated protein A
VVMO6_RS13640	COG3266	domain, Protein
VVMO6_RS13645	COG0545	Peptidyl-prolyl cis-trans isomerase
VVMO6_RS13655	COG0203	ribosomal protein L17
VVMO6_RS13660	COG0202	RNA polymerase activity
VVMO6_RS13665	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
VVMO6_RS13670	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
VVMO6_RS13675	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
VVMO6_RS13680	COG0257	Belongs to the bacterial ribosomal protein bL36 family
VVMO6_RS13685	COG0201	protein transport
VVMO6_RS13690	COG0200	Binds to the 23S rRNA
VVMO6_RS13695	COG1841	ribosomal large subunit assembly
VVMO6_RS13700	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
VVMO6_RS13705	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
VVMO6_RS13710	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
VVMO6_RS13715	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
VVMO6_RS13720	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
VVMO6_RS13725	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
VVMO6_RS13730	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
VVMO6_RS13735	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
VVMO6_RS13740	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
VVMO6_RS13745	COG0255	Belongs to the universal ribosomal protein uL29 family
VVMO6_RS13750	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
VVMO6_RS13755	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
VVMO6_RS13765	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
VVMO6_RS13770	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
VVMO6_RS13775	COG0089	rRNA binding
VVMO6_RS13780	COG0088	Forms part of the polypeptide exit tunnel
VVMO6_RS13795	COG3064	Membrane
VVMO6_RS13800	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
VVMO6_RS13810	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
VVMO6_RS13820	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
VVMO6_RS13875	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
VVMO6_RS13895	COG1596	polysaccharide export
VVMO6_RS13950	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VVMO6_RS13965	COG0859	PFAM glycosyl transferase family 9
VVMO6_RS13970	COG1519	Transferase
VVMO6_RS13990	COG1083	cytidylyl-transferase
VVMO6_RS14010	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
VVMO6_RS14015	COG2089	acid synthase
VVMO6_RS14025	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
VVMO6_RS14040	COG3083	sulfuric ester hydrolase activity
VVMO6_RS14050	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
VVMO6_RS14055	COG0859	PFAM glycosyl transferase family 9
VVMO6_RS14060	COG0463	Glycosyl transferase, family 2
VVMO6_RS14065	COG0859	PFAM glycosyl transferase family 9
VVMO6_RS14070	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
VVMO6_RS14090	COG0267	Belongs to the bacterial ribosomal protein bL33 family
VVMO6_RS14095	COG0227	Belongs to the bacterial ribosomal protein bL28 family
VVMO6_RS14100	COG2003	Belongs to the UPF0758 family
VVMO6_RS14110	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
VVMO6_RS14115	COG1309	transcriptional regulator
VVMO6_RS14120	COG1560	Kdo2-lipid A biosynthetic process
VVMO6_RS14130	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
VVMO6_RS14135	COG1561	YicC-like family, N-terminal region
VVMO6_RS14155	COG4608	Belongs to the ABC transporter superfamily
VVMO6_RS14160	COG0444	Belongs to the ABC transporter superfamily
VVMO6_RS14165	COG0747	negative chemotaxis
VVMO6_RS14170	COG4239	(ABC) transporter, permease
VVMO6_RS14175	COG4174	ABC transporter (Permease)
VVMO6_RS14180	COG4206	TonB-dependent receptor
VVMO6_RS14190	COG0811	peptide transport
VVMO6_RS14195	COG0811	peptide transport
VVMO6_RS14200	COG0848	biopolymer transport protein
VVMO6_RS14215	COG0194	GDP metabolic process
VVMO6_RS14220	COG1758	RNA polymerase activity
VVMO6_RS14225	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
VVMO6_RS14230	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
VVMO6_RS14235	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
VVMO6_RS14240	COG2233	PERMEase
VVMO6_RS14255	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
VVMO6_RS14260	COG2183	response to ionizing radiation
VVMO6_RS14270	COG0596	Alpha beta hydrolase
VVMO6_RS14280	COG0316	Belongs to the HesB IscA family
VVMO6_RS14280	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
VVMO6_RS14285	COG0494	nUDIX hydrolase
VVMO6_RS14290	COG1218	3'(2'),5'-bisphosphate nucleotidase
VVMO6_RS14300	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
VVMO6_RS14305	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
VVMO6_RS14310	COG3156	type II secretion system protein K
VVMO6_RS14315	COG4795	General secretion pathway protein
VVMO6_RS14320	COG2165	general secretion pathway protein
VVMO6_RS14325	COG2165	general secretion pathway protein
VVMO6_RS14330	COG2165	general secretion pathway protein
VVMO6_RS14335	COG1459	type II secretion system
VVMO6_RS14340	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
VVMO6_RS14350	COG3031	protein transport across the cell outer membrane
VVMO6_RS14355	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
VVMO6_RS14360	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
VVMO6_RS14375	COG0456	acetyltransferase
VVMO6_RS14380	COG1490	D-aminoacyl-tRNA deacylase activity
VVMO6_RS14400	COG1217	gtp-binding protein TYPA
VVMO6_RS14405	COG0174	glutamine synthetase
VVMO6_RS14415	COG3852	Histidine kinase
VVMO6_RS14460	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
VVMO6_RS14460	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
VVMO6_RS14470	COG0084	hydrolase, TatD family'
VVMO6_RS14475	COG0805	protein transport
VVMO6_RS14480	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
VVMO6_RS14485	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
VVMO6_RS14495	COG3165	ubiquinone biosynthetic process from chorismate
VVMO6_RS14500	COG2226	methyltransferase
VVMO6_RS14505	COG1322	Protein conserved in bacteria
VVMO6_RS14520	COG3335	DDE superfamily endonuclease
VVMO6_RS14585	COG3118	belongs to the thioredoxin family
VVMO6_RS14595	COG0248	Ppx GppA phosphatase
VVMO6_RS14600	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
VVMO6_RS14610	COG0514	ATP-dependent DNA helicase (RecQ)
VVMO6_RS14615	COG2962	Rard protein
VVMO6_RS14625	COG1280	lysine exporter protein (LysE YggA)
VVMO6_RS14630	COG0210	DNA helicase
VVMO6_RS14670	COG0006	proline dipeptidase activity
VVMO6_RS14670	COG0006	proline dipeptidase activity
VVMO6_RS14680	COG2022	thiamine diphosphate biosynthetic process
VVMO6_RS14690	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
VVMO6_RS14700	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
VVMO6_RS14705	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
VVMO6_RS14710	COG2132	Multicopper oxidase
VVMO6_RS14720	COG3335	DDE superfamily endonuclease
VVMO6_RS14760	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
VVMO6_RS14765	COG1739	Uncharacterized protein family UPF0029
VVMO6_RS14780	COG0604	alcohol dehydrogenase
VVMO6_RS14795	COG0425	Belongs to the sulfur carrier protein TusA family
VVMO6_RS14805	COG2119	membrane
VVMO6_RS14810	COG0752	glycyl-tRNA synthetase alpha subunit
VVMO6_RS14815	COG0751	glycine-tRNA ligase activity
VVMO6_RS14825	COG3977	Valine--pyruvate aminotransferase
VVMO6_RS14835	COG0071	Belongs to the small heat shock protein (HSP20) family
VVMO6_RS14840	COG0187	DNA topoisomerase II activity
VVMO6_RS14850	COG0592	DNA-directed DNA polymerase activity
VVMO6_RS14870	COG1126	abc transporter atp-binding protein
VVMO6_RS14875	COG0230	Belongs to the bacterial ribosomal protein bL34 family
VVMO6_RS14880	COG0594	ribonuclease P activity
VVMO6_RS14895	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
VVMO6_RS14950	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
VVMO6_RS15385	COG2199	diguanylate cyclase activity
VVMO6_RS15385	COG2200	EAL domain
VVMO6_RS15385	COG3287	FIST C domain
VVMO6_RS16005	COG0557	exoribonuclease II activity
VVMO6_RS16140	COG1446	asparaginase
VVMO6_RS16290	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
VVMO6_RS16365	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
VVMO6_RS16505	COG0527	aspartate kinase activity
VVMO6_RS16525	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
VVMO6_RS16670	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
VVMO6_RS16730	COG0525	valine-tRNA ligase activity
VVMO6_RS16900	COG2066	Belongs to the glutaminase family
VVMO6_RS16970	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
VVMO6_RS17070	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
VVMO6_RS17225	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
VVMO6_RS17360	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
VVMO6_RS17695	COG0779	Required for maturation of 30S ribosomal subunits
VVMO6_RS18125	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
VVMO6_RS18165	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
VVMO6_RS18225	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
VVMO6_RS18280	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
VVMO6_RS18315	COG0514	ATP-dependent DNA helicase (RecQ)
VVMO6_RS18470	COG0587	DNA-directed DNA polymerase activity
VVMO6_RS18900	COG2067	long-chain fatty acid transport protein
VVMO6_RS19025	COG0101	tRNA pseudouridine synthase activity
VVMO6_RS19075	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
VVMO6_RS19255	COG1982	Orn Lys Arg decarboxylase major
VVMO6_RS19405	COG2766	serine protein kinase
VVMO6_RS19470	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VVMO6_RS19555	COG0542	response to heat
VVMO6_RS19680	COG1271	oxidase subunit
VVMO6_RS19720	COG2885	chlorophyll binding
VVMO6_RS20170	COG2770	Histidine kinase
VVMO6_RS20170	COG3437	response regulator, receiver
VVMO6_RS20670	COG1643	Atp-dependent helicase
VVMO6_RS20865	COG5640	endopeptidase activity
VVMO6_RS21455	COG0534	Mate efflux family protein
VVMO6_RS21545	COG3842	ATPase activity
VVMO6_RS21820	COG2902	Dehydrogenase
VVMO6_RS21840	COG0308	aminopeptidase N
VVMO6_RS22125	COG3008	intermembrane lipid transfer
VVMO6_RS22250	COG0363	glucosamine-6-phosphate deaminase activity
VVMO6_RS22320	COG0437	4 iron, 4 sulfur cluster binding
VVMO6_RS22425	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
VVMO6_RS22500	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
VVMO6_RS22535	COG1403	HNH endonuclease
VVMO6_RS22540	COG1040	competence protein