locus-tag	class	description
BWZ32_RS00055	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BWZ32_RS00085	COG0735	belongs to the Fur family
BWZ32_RS00100	COG0432	Pfam Uncharacterised protein family UPF0047
BWZ32_RS00110	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BWZ32_RS00125	COG0359	binds to the 23S rRNA
BWZ32_RS00135	COG2965	DNA replication, synthesis of RNA primer
BWZ32_RS00140	COG0360	Binds together with S18 to 16S ribosomal RNA
BWZ32_RS00145	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BWZ32_RS00150	COG0338	D12 class N6 adenine-specific DNA methyltransferase
BWZ32_RS00160	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BWZ32_RS00165	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BWZ32_RS00195	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BWZ32_RS00210	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BWZ32_RS00210	COG0165	Argininosuccinate lyase
BWZ32_RS00215	COG0137	argininosuccinate synthase activity
BWZ32_RS00230	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BWZ32_RS00235	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BWZ32_RS00245	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BWZ32_RS00250	COG0527	aspartate kinase activity
BWZ32_RS00250	COG0460	homoserine dehydrogenase
BWZ32_RS00255	COG0626	cystathionine gamma-synthase activity
BWZ32_RS00260	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
BWZ32_RS00265	COG0281	malic enzyme
BWZ32_RS00270	COG0254	rRNA binding
BWZ32_RS00275	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BWZ32_RS00280	COG1609	Transcriptional regulator
BWZ32_RS00290	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BWZ32_RS00295	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BWZ32_RS00300	COG1575	Belongs to the MenA family. Type 1 subfamily
BWZ32_RS00310	COG3074	FtsZ-dependent cytokinesis
BWZ32_RS00315	COG1494	fructose-1,6-bisphosphatase
BWZ32_RS00340	COG0149	triose-phosphate isomerase activity
BWZ32_RS00345	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BWZ32_RS00355	COG2906	2 iron, 2 sulfur cluster binding
BWZ32_RS00365	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BWZ32_RS00370	COG0049	tRNA binding
BWZ32_RS00375	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BWZ32_RS00380	COG2168	tRNA wobble position uridine thiolation
BWZ32_RS00395	COG2964	Protein conserved in bacteria
BWZ32_RS00400	COG0545	Peptidyl-prolyl cis-trans isomerase
BWZ32_RS00410	COG2900	Belongs to the SlyX family
BWZ32_RS00420	COG1047	Peptidyl-prolyl cis-trans
BWZ32_RS00435	COG2249	NAD(P)H dehydrogenase (quinone) activity
BWZ32_RS00440	COG0488	(ABC) transporter
BWZ32_RS00450	COG0429	hydrolase of the alpha beta-hydrolase fold
BWZ32_RS00455	COG3089	Belongs to the UPF0270 family
BWZ32_RS00460	COG3954	Phosphoribulokinase
BWZ32_RS00465	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BWZ32_RS00485	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BWZ32_RS00515	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BWZ32_RS00520	COG0557	exoribonuclease II activity
BWZ32_RS00525	COG0402	S-adenosylhomocysteine deaminase activity
BWZ32_RS00530	COG1959	2 iron, 2 sulfur cluster binding
BWZ32_RS00540	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
BWZ32_RS00545	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BWZ32_RS00550	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
BWZ32_RS00555	COG0330	HflC and HflK could
BWZ32_RS00560	COG0330	HflC and HflK could
BWZ32_RS00565	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BWZ32_RS00570	COG1923	regulation of RNA biosynthetic process
BWZ32_RS00585	COG0860	N-Acetylmuramoyl-L-alanine amidase
BWZ32_RS00590	COG0802	atpase or kinase
BWZ32_RS00595	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BWZ32_RS00655	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
BWZ32_RS00660	COG1162	GTPase activity
BWZ32_RS00665	COG0688	phosphatidylethanolamine metabolic process
BWZ32_RS00670	COG0471	metal ion transport
BWZ32_RS00690	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BWZ32_RS00695	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
BWZ32_RS00700	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BWZ32_RS00705	COG1045	serine acetyltransferase
BWZ32_RS00710	COG4942	peptidase
BWZ32_RS00730	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
BWZ32_RS00735	COG1053	succinate dehydrogenase
BWZ32_RS00740	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BWZ32_RS00745	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
BWZ32_RS00750	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
BWZ32_RS00760	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BWZ32_RS00765	COG1509	lysine 2,3-aminomutase activity
BWZ32_RS00770	COG1285	pathogenesis
BWZ32_RS00780	COG0459	protein refolding
BWZ32_RS00785	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BWZ32_RS00790	COG0534	Mate efflux family protein
BWZ32_RS00795	COG0205	6-phosphofructokinase activity
BWZ32_RS00805	COG3678	ATP-independent chaperone mediated protein folding
BWZ32_RS00810	COG0745	RESPONSE REGULATOR receiver
BWZ32_RS00815	COG2205	protein histidine kinase activity
BWZ32_RS00825	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BWZ32_RS00835	COG1027	Aspartate ammonia-lyase
BWZ32_RS00845	COG4232	protein-disulfide reductase activity
BWZ32_RS00855	COG2095	MarC family integral membrane protein
BWZ32_RS00865	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BWZ32_RS00885	COG0784	Response regulator, receiver
BWZ32_RS00885	COG2205	protein histidine kinase activity
BWZ32_RS00885	COG2198	Histidine kinase
BWZ32_RS00890	COG2814	Major facilitator Superfamily
BWZ32_RS00905	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BWZ32_RS00910	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BWZ32_RS00915	COG0511	ligase activity, forming carbon-carbon bonds
BWZ32_RS00920	COG0439	Biotin carboxylase
BWZ32_RS00935	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
BWZ32_RS00940	COG0840	transmembrane signaling receptor activity
BWZ32_RS00945	COG0789	Transcriptional regulator
BWZ32_RS00955	COG0138	bifunctional purine biosynthesis protein purh
BWZ32_RS00975	COG1253	flavin adenine dinucleotide binding
BWZ32_RS00980	COG3068	Protein conserved in bacteria
BWZ32_RS00985	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BWZ32_RS00990	COG1573	uracil-dna glycosylase
BWZ32_RS00995	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BWZ32_RS01015	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
BWZ32_RS01020	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BWZ32_RS01025	COG0085	RNA polymerase activity
BWZ32_RS01030	COG0222	ribosome binding
BWZ32_RS01035	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BWZ32_RS01040	COG0081	regulation of translation
BWZ32_RS01055	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BWZ32_RS01060	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BWZ32_RS01095	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BWZ32_RS01105	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BWZ32_RS01115	COG3335	DDE superfamily endonuclease
BWZ32_RS01210	COG3118	belongs to the thioredoxin family
BWZ32_RS01220	COG0248	Ppx GppA phosphatase
BWZ32_RS01225	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BWZ32_RS01235	COG0514	ATP-dependent DNA helicase (RecQ)
BWZ32_RS01240	COG2962	Rard protein
BWZ32_RS01250	COG1280	lysine exporter protein (LysE YggA)
BWZ32_RS01255	COG0210	DNA helicase
BWZ32_RS01295	COG0006	proline dipeptidase activity
BWZ32_RS01295	COG0006	proline dipeptidase activity
BWZ32_RS01305	COG2022	thiamine diphosphate biosynthetic process
BWZ32_RS01315	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BWZ32_RS01325	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BWZ32_RS01330	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BWZ32_RS01380	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BWZ32_RS01390	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BWZ32_RS01395	COG0408	coproporphyrinogen oxidase activity
BWZ32_RS01400	COG0009	L-threonylcarbamoyladenylate synthase
BWZ32_RS01405	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BWZ32_RS01415	COG0551	DNA topoisomerase type I activity
BWZ32_RS01420	COG2922	Belongs to the Smg family
BWZ32_RS01425	COG0758	DNA mediated transformation
BWZ32_RS01435	COG0242	peptide deformylase activity
BWZ32_RS01440	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BWZ32_RS01445	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BWZ32_RS01445	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BWZ32_RS01450	COG0569	domain protein
BWZ32_RS01455	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BWZ32_RS01460	COG1272	protein, Hemolysin III
BWZ32_RS01465	COG4326	sporulation control protein
BWZ32_RS01470	COG3084	Protein conserved in bacteria
BWZ32_RS01480	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BWZ32_RS01485	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BWZ32_RS01490	COG0204	Acyl-transferase
BWZ32_RS01500	COG0606	chelatase, subunit chli
BWZ32_RS01510	COG3978	acetolactate synthase activity
BWZ32_RS01515	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BWZ32_RS01530	COG0583	DNA-binding transcription factor activity
BWZ32_RS01535	COG2814	Major facilitator Superfamily
BWZ32_RS01545	COG0765	amino acid transport
BWZ32_RS01550	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BWZ32_RS01555	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BWZ32_RS01560	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BWZ32_RS01565	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BWZ32_RS01570	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BWZ32_RS01575	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BWZ32_RS01580	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BWZ32_RS01590	COG0356	it plays a direct role in the translocation of protons across the membrane
BWZ32_RS01595	COG3312	ion transport
BWZ32_RS01600	COG1475	DNA binding
BWZ32_RS01605	COG1192	Involved in chromosome partitioning
BWZ32_RS01610	COG0357	Ribosomal RNA small subunit methyltransferase G
BWZ32_RS01625	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BWZ32_RS01645	COG0594	ribonuclease P activity
BWZ32_RS01650	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BWZ32_RS01655	COG1126	abc transporter atp-binding protein
BWZ32_RS01675	COG0592	DNA-directed DNA polymerase activity
BWZ32_RS01685	COG0187	DNA topoisomerase II activity
BWZ32_RS01690	COG0071	Belongs to the small heat shock protein (HSP20) family
BWZ32_RS01700	COG3977	Valine--pyruvate aminotransferase
BWZ32_RS01710	COG0751	glycine-tRNA ligase activity
BWZ32_RS01715	COG0752	glycyl-tRNA synthetase alpha subunit
BWZ32_RS01720	COG2119	membrane
BWZ32_RS01730	COG0425	Belongs to the sulfur carrier protein TusA family
BWZ32_RS01745	COG0604	alcohol dehydrogenase
BWZ32_RS01760	COG1739	Uncharacterized protein family UPF0029
BWZ32_RS01765	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BWZ32_RS01815	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BWZ32_RS01820	COG2960	long-chain fatty acid transporting porin activity
BWZ32_RS01825	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BWZ32_RS01830	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BWZ32_RS01835	COG1309	transcriptional regulator
BWZ32_RS01875	COG4172	Belongs to the ABC transporter superfamily
BWZ32_RS01880	COG4166	transmembrane transport
BWZ32_RS01885	COG0601	transmembrane transport
BWZ32_RS01890	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BWZ32_RS01925	COG2815	serine threonine protein kinase
BWZ32_RS01925	COG0515	serine threonine protein kinase
BWZ32_RS01935	COG0745	RESPONSE REGULATOR receiver
BWZ32_RS01940	COG1609	Transcriptional regulator
BWZ32_RS01945	COG0129	dihydroxy-acid dehydratase activity
BWZ32_RS01950	COG3265	gluconokinase activity
BWZ32_RS01955	COG2610	gluconate transmembrane transporter activity
BWZ32_RS01960	COG0800	Aldolase
BWZ32_RS01975	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BWZ32_RS01980	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BWZ32_RS01990	COG1522	sequence-specific DNA binding
BWZ32_RS01995	COG5002	protein histidine kinase activity
BWZ32_RS01995	COG5001	Diguanylate cyclase
BWZ32_RS02000	COG0742	ribosomal rna small subunit methyltransferase
BWZ32_RS02015	COG0589	response to stress
BWZ32_RS02020	COG1528	Iron-storage protein
BWZ32_RS02030	COG2081	HI0933 family
BWZ32_RS02040	COG2959	enzyme of heme biosynthesis
BWZ32_RS02050	COG0181	hydroxymethylbilane synthase activity
BWZ32_RS02055	COG3072	Adenylate cyclase
BWZ32_RS02060	COG1965	Belongs to the frataxin family
BWZ32_RS02070	COG0019	diaminopimelate decarboxylase activity
BWZ32_RS02075	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BWZ32_RS02085	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BWZ32_RS02090	COG1011	Hydrolase
BWZ32_RS02095	COG2199	diguanylate cyclase activity
BWZ32_RS02095	COG2200	EAL domain
BWZ32_RS02095	COG3287	FIST C domain
BWZ32_RS02100	COG3148	PFAM DTW domain containing protein
BWZ32_RS02115	COG0561	phosphatase activity
BWZ32_RS02120	COG2267	carboxylic ester hydrolase activity
BWZ32_RS02125	COG1280	lysine exporter protein (LysE YggA)
BWZ32_RS02130	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
BWZ32_RS02135	COG0640	Transcriptional regulator
BWZ32_RS02140	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BWZ32_RS02185	COG2095	MarC family integral membrane protein
BWZ32_RS02195	COG0742	ribosomal rna small subunit methyltransferase
BWZ32_RS02200	COG0552	protein localization to endoplasmic reticulum
BWZ32_RS02205	COG2884	Cell division ATP-binding protein ftsE
BWZ32_RS02210	COG2177	Part of the ABC transporter FtsEX involved in
BWZ32_RS02220	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BWZ32_RS02230	COG1580	Controls the rotational direction of flagella during chemotaxis
BWZ32_RS02260	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BWZ32_RS02270	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BWZ32_RS02285	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BWZ32_RS02290	COG4206	TonB-dependent receptor
BWZ32_RS02370	COG3335	DDE superfamily endonuclease
BWZ32_RS02390	COG1322	Protein conserved in bacteria
BWZ32_RS02395	COG2226	methyltransferase
BWZ32_RS02400	COG3165	ubiquinone biosynthetic process from chorismate
BWZ32_RS02410	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BWZ32_RS02415	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BWZ32_RS02420	COG0805	protein transport
BWZ32_RS02425	COG0084	hydrolase, TatD family'
BWZ32_RS02435	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BWZ32_RS02435	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BWZ32_RS02455	COG3078	GTPase activator activity
BWZ32_RS02470	COG3300	MHYT domain
BWZ32_RS02470	COG5001	Diguanylate cyclase
BWZ32_RS02475	COG2204	response regulator
BWZ32_RS02480	COG3852	Histidine kinase
BWZ32_RS02490	COG0174	glutamine synthetase
BWZ32_RS02500	COG1217	gtp-binding protein TYPA
BWZ32_RS02505	COG1660	Displays ATPase and GTPase activities
BWZ32_RS02515	COG1295	ribonuclease BN
BWZ32_RS02520	COG1490	D-aminoacyl-tRNA deacylase activity
BWZ32_RS02525	COG0456	acetyltransferase
BWZ32_RS02540	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BWZ32_RS02545	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BWZ32_RS02550	COG3031	protein transport across the cell outer membrane
BWZ32_RS02560	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BWZ32_RS02565	COG1459	type II secretion system
BWZ32_RS02570	COG2165	general secretion pathway protein
BWZ32_RS02575	COG2165	general secretion pathway protein
BWZ32_RS02580	COG2165	general secretion pathway protein
BWZ32_RS02585	COG4795	General secretion pathway protein
BWZ32_RS02590	COG3156	type II secretion system protein K
BWZ32_RS02595	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
BWZ32_RS02600	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
BWZ32_RS02610	COG1218	3'(2'),5'-bisphosphate nucleotidase
BWZ32_RS02615	COG0494	nUDIX hydrolase
BWZ32_RS02620	COG0316	Belongs to the HesB IscA family
BWZ32_RS02620	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BWZ32_RS02625	COG1040	competence protein
BWZ32_RS02630	COG0596	Alpha beta hydrolase
BWZ32_RS02640	COG2183	response to ionizing radiation
BWZ32_RS02660	COG2233	PERMEase
BWZ32_RS02665	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BWZ32_RS02670	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BWZ32_RS02675	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BWZ32_RS02680	COG1758	RNA polymerase activity
BWZ32_RS02685	COG0194	GDP metabolic process
BWZ32_RS02700	COG0848	biopolymer transport protein
BWZ32_RS02705	COG0811	peptide transport
BWZ32_RS02710	COG0811	peptide transport
BWZ32_RS02720	COG4206	TonB-dependent receptor
BWZ32_RS02725	COG4174	ABC transporter (Permease)
BWZ32_RS02730	COG4239	(ABC) transporter, permease
BWZ32_RS02735	COG0747	negative chemotaxis
BWZ32_RS02740	COG0444	Belongs to the ABC transporter superfamily
BWZ32_RS02745	COG4608	Belongs to the ABC transporter superfamily
BWZ32_RS02795	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
BWZ32_RS02800	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
BWZ32_RS02840	COG1396	sequence-specific DNA binding
BWZ32_RS02855	COG1561	YicC-like family, N-terminal region
BWZ32_RS02860	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BWZ32_RS02870	COG1560	Kdo2-lipid A biosynthetic process
BWZ32_RS02875	COG1309	transcriptional regulator
BWZ32_RS02880	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BWZ32_RS02890	COG2003	Belongs to the UPF0758 family
BWZ32_RS02895	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BWZ32_RS02900	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BWZ32_RS02910	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BWZ32_RS02920	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BWZ32_RS02925	COG0859	PFAM glycosyl transferase family 9
BWZ32_RS02930	COG0463	Glycosyl transferase, family 2
BWZ32_RS02935	COG0859	PFAM glycosyl transferase family 9
BWZ32_RS02940	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BWZ32_RS02945	COG3642	lipopolysaccharide core region biosynthetic process
BWZ32_RS02950	COG3083	sulfuric ester hydrolase activity
BWZ32_RS02965	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BWZ32_RS02970	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BWZ32_RS02975	COG2089	acid synthase
BWZ32_RS03000	COG1083	cytidylyl-transferase
BWZ32_RS03005	COG1028	Short-chain dehydrogenase reductase Sdr
BWZ32_RS03020	COG0318	PFAM AMP-dependent synthetase and ligase
BWZ32_RS03050	COG1519	Transferase
BWZ32_RS03055	COG0859	PFAM glycosyl transferase family 9
BWZ32_RS03060	COG1560	Kdo2-lipid A biosynthetic process
BWZ32_RS03065	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BWZ32_RS03070	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BWZ32_RS03115	COG1596	polysaccharide export
BWZ32_RS03140	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BWZ32_RS03145	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BWZ32_RS03190	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BWZ32_RS03200	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BWZ32_RS03230	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
BWZ32_RS03255	COG0088	Forms part of the polypeptide exit tunnel
BWZ32_RS03260	COG0089	rRNA binding
BWZ32_RS03265	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BWZ32_RS03270	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BWZ32_RS03280	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BWZ32_RS03285	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BWZ32_RS03290	COG0255	Belongs to the universal ribosomal protein uL29 family
BWZ32_RS03295	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BWZ32_RS03300	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BWZ32_RS03305	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BWZ32_RS03310	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BWZ32_RS03315	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BWZ32_RS03320	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BWZ32_RS03325	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BWZ32_RS03330	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BWZ32_RS03335	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BWZ32_RS03340	COG1841	ribosomal large subunit assembly
BWZ32_RS03345	COG0200	Binds to the 23S rRNA
BWZ32_RS03350	COG0201	protein transport
BWZ32_RS03355	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BWZ32_RS03360	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BWZ32_RS03365	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BWZ32_RS03370	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BWZ32_RS03375	COG0202	RNA polymerase activity
BWZ32_RS03380	COG0203	ribosomal protein L17
BWZ32_RS03390	COG0545	Peptidyl-prolyl cis-trans isomerase
BWZ32_RS03395	COG3266	domain, Protein
BWZ32_RS03395	COG3061	Opacity-associated protein A
BWZ32_RS03405	COG2153	protein acetylation
BWZ32_RS03415	COG0737	Belongs to the 5'-nucleotidase family
BWZ32_RS03420	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BWZ32_RS03420	COG1648	precorrin-2 dehydrogenase activity
BWZ32_RS03425	COG0175	sulfate reduction
BWZ32_RS03430	COG2895	sulfate adenylyltransferase (ATP) activity
BWZ32_RS03435	COG0471	metal ion transport
BWZ32_RS03435	COG3273	potassium ion transport
BWZ32_RS03440	COG0529	Catalyzes the synthesis of activated sulfate
BWZ32_RS03460	COG1136	(ABC) transporter
BWZ32_RS03460	COG0577	efflux transmembrane transporter activity
BWZ32_RS03475	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
BWZ32_RS03490	COG0729	surface antigen
BWZ32_RS03495	COG2911	Protein conserved in bacteria
BWZ32_RS03500	COG2105	PFAM AIG2 family protein
BWZ32_RS03510	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BWZ32_RS03515	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
BWZ32_RS03520	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BWZ32_RS03525	COG0163	prenyltransferase activity
BWZ32_RS03530	COG4143	(ABC) transporter
BWZ32_RS03535	COG1178	ABC-type Fe3 transport system permease component
BWZ32_RS03540	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
BWZ32_RS03545	COG3028	Belongs to the UPF0307 family
BWZ32_RS03550	COG0312	modulator of DNA gyrase
BWZ32_RS03555	COG2239	Acts as a magnesium transporter
BWZ32_RS03560	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BWZ32_RS03565	COG1660	Displays ATPase and GTPase activities
BWZ32_RS03570	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BWZ32_RS03575	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BWZ32_RS03585	COG1137	ATPase activity
BWZ32_RS03590	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
BWZ32_RS03605	COG0517	IMP dehydrogenase activity
BWZ32_RS03605	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BWZ32_RS03615	COG1127	ABC transporter
BWZ32_RS03620	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BWZ32_RS03625	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BWZ32_RS03630	COG2854	intermembrane phospholipid transfer
BWZ32_RS03640	COG5007	Belongs to the BolA IbaG family
BWZ32_RS03650	COG0204	Acyl-transferase
BWZ32_RS03655	COG0589	response to stress
BWZ32_RS03665	COG2358	TRAP transporter, solute receptor (TAXI family
BWZ32_RS03670	COG1438	arginine binding
BWZ32_RS03675	COG0039	L-malate dehydrogenase activity
BWZ32_RS03680	COG0142	geranyltranstransferase activity
BWZ32_RS03685	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BWZ32_RS03690	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BWZ32_RS03700	COG2966	Psort location CytoplasmicMembrane, score
BWZ32_RS03705	COG3610	response to peptide
BWZ32_RS03720	COG2967	ApaG domain
BWZ32_RS03725	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BWZ32_RS03730	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BWZ32_RS03765	COG0473	3-isopropylmalate dehydrogenase activity
BWZ32_RS03770	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BWZ32_RS03795	COG1022	Amp-dependent synthetase and ligase
BWZ32_RS03800	COG0028	Belongs to the TPP enzyme family
BWZ32_RS03805	COG0440	acetolactate synthase activity
BWZ32_RS03810	COG3706	GGDEF domain
BWZ32_RS03825	COG1349	DNA-binding transcription factor activity
BWZ32_RS03835	COG3722	fumarate hydratase activity
BWZ32_RS03845	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BWZ32_RS03845	COG2213	PTS system mannitol-specific
BWZ32_RS03850	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BWZ32_RS03870	COG2378	regulation of single-species biofilm formation
BWZ32_RS03940	COG1610	YqeY-like protein
BWZ32_RS03945	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BWZ32_RS03950	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BWZ32_RS03955	COG0596	Alpha beta hydrolase
BWZ32_RS03965	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BWZ32_RS03970	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BWZ32_RS03975	COG1968	undecaprenyl-diphosphatase activity
BWZ32_RS03980	COG0617	tRNA 3'-terminal CCA addition
BWZ32_RS03985	COG3409	Peptidoglycan-binding domain 1 protein
BWZ32_RS03985	COG3267	Type II secretory pathway component ExeA
BWZ32_RS03990	COG4991	sh3 domain protein
BWZ32_RS03995	COG0306	phosphate transporter
BWZ32_RS04000	COG1392	Phosphate transport regulator
BWZ32_RS04005	COG3025	triphosphatase activity
BWZ32_RS04010	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BWZ32_RS04020	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
BWZ32_RS04030	COG1538	Outer membrane efflux protein
BWZ32_RS04035	COG0494	nUDIX hydrolase
BWZ32_RS04040	COG3151	Protein conserved in bacteria
BWZ32_RS04050	COG3150	esterase
BWZ32_RS04065	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BWZ32_RS04070	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BWZ32_RS04075	COG3105	Protein conserved in bacteria
BWZ32_RS04080	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BWZ32_RS04090	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BWZ32_RS04095	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BWZ32_RS04100	COG0723	plastoquinol--plastocyanin reductase activity
BWZ32_RS04105	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BWZ32_RS04110	COG2857	Cytochrome c1
BWZ32_RS04115	COG0625	glutathione transferase activity
BWZ32_RS04120	COG2969	positive regulation of protein catabolic process
BWZ32_RS04125	COG2823	Periplasmic or secreted lipoprotein
BWZ32_RS04130	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
BWZ32_RS04135	COG0792	nuclease activity
BWZ32_RS04140	COG3107	peptidoglycan biosynthetic process
BWZ32_RS04145	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BWZ32_RS04155	COG0275	rRNA processing
BWZ32_RS04160	COG3116	cell division
BWZ32_RS04165	COG0768	penicillin binding
BWZ32_RS04170	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BWZ32_RS04175	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BWZ32_RS04180	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BWZ32_RS04185	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BWZ32_RS04190	COG0772	Belongs to the SEDS family
BWZ32_RS04200	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BWZ32_RS04205	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BWZ32_RS04210	COG0849	cell division
BWZ32_RS04215	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BWZ32_RS04220	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
BWZ32_RS04230	COG0653	protein targeting
BWZ32_RS04235	COG0494	nUDIX hydrolase
BWZ32_RS04245	COG0505	Belongs to the CarA family
BWZ32_RS04250	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BWZ32_RS04260	COG0730	response to heat
BWZ32_RS04265	COG0583	DNA-binding transcription factor activity
BWZ32_RS04270	COG2860	membrane
BWZ32_RS04275	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BWZ32_RS04285	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BWZ32_RS04295	COG0493	'glutamate synthase
BWZ32_RS04300	COG0070	glutamate synthase
BWZ32_RS04300	COG0067	glutamate synthase
BWZ32_RS04300	COG0069	glutamate synthase activity
BWZ32_RS04310	COG0069	glutamate synthase activity
BWZ32_RS04310	COG0070	glutamate synthase
BWZ32_RS04310	COG0067	glutamate synthase
BWZ32_RS04315	COG1242	4 iron, 4 sulfur cluster binding
BWZ32_RS04320	COG4251	negative regulation of phosphorylation
BWZ32_RS04320	COG5001	Diguanylate cyclase
BWZ32_RS04320	COG3706	GGDEF domain
BWZ32_RS04320	COG2203	Gaf domain
BWZ32_RS04325	COG2198	Histidine kinase
BWZ32_RS04325	COG0784	Response regulator, receiver
BWZ32_RS04325	COG5002	protein histidine kinase activity
BWZ32_RS04335	COG0745	RESPONSE REGULATOR receiver
BWZ32_RS04350	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BWZ32_RS04365	COG0083	homoserine kinase activity
BWZ32_RS04370	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BWZ32_RS04375	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
BWZ32_RS04385	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BWZ32_RS04400	COG1115	amino acid carrier protein
BWZ32_RS04410	COG0513	Belongs to the DEAD box helicase family
BWZ32_RS04430	COG4974	Belongs to the 'phage' integrase family
BWZ32_RS04435	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BWZ32_RS04440	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BWZ32_RS04450	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BWZ32_RS04465	COG0667	Aldo Keto reductase
BWZ32_RS04475	COG3066	DNA modification
BWZ32_RS04480	COG0494	nUDIX hydrolase
BWZ32_RS04490	COG0730	response to heat
BWZ32_RS04510	COG1283	sodium-dependent phosphate transmembrane transporter activity
BWZ32_RS04515	COG0583	DNA-binding transcription factor activity
BWZ32_RS04520	COG0640	Transcriptional regulator
BWZ32_RS04525	COG0268	Binds directly to 16S ribosomal RNA
BWZ32_RS04530	COG0728	peptidoglycan biosynthetic process
BWZ32_RS04535	COG0196	riboflavin kinase activity
BWZ32_RS04540	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BWZ32_RS04545	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BWZ32_RS04550	COG1047	Peptidyl-prolyl cis-trans
BWZ32_RS04555	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BWZ32_RS04565	COG3275	phosphorelay sensor kinase activity
BWZ32_RS04570	COG1966	Carbon starvation protein
BWZ32_RS04590	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
BWZ32_RS04605	COG0287	Prephenate dehydrogenase
BWZ32_RS04605	COG1605	Chorismate mutase
BWZ32_RS04610	COG0739	heme binding
BWZ32_RS04620	COG0488	(ABC) transporter
BWZ32_RS04630	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
BWZ32_RS04635	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
BWZ32_RS04640	COG1605	Chorismate mutase
BWZ32_RS04640	COG0077	Prephenate dehydratase
BWZ32_RS04645	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BWZ32_RS04650	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BWZ32_RS04665	COG0542	response to heat
BWZ32_RS04705	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BWZ32_RS04710	COG0826	peptidase U32
BWZ32_RS04720	COG0745	RESPONSE REGULATOR receiver
BWZ32_RS04725	COG5002	protein histidine kinase activity
BWZ32_RS04735	COG0248	Ppx GppA phosphatase
BWZ32_RS04745	COG0573	inorganic phosphate transmembrane transporter activity
BWZ32_RS04750	COG0581	inorganic phosphate transmembrane transporter activity
BWZ32_RS04755	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BWZ32_RS04760	COG0704	Plays a role in the regulation of phosphate uptake
BWZ32_RS04795	COG0450	alkyl hydroperoxide reductase
BWZ32_RS04800	COG0583	DNA-binding transcription factor activity
BWZ32_RS04805	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BWZ32_RS04815	COG0517	IMP dehydrogenase activity
BWZ32_RS04825	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BWZ32_RS04830	COG0343	queuine tRNA-ribosyltransferase activity
BWZ32_RS04835	COG1862	Preprotein translocase
BWZ32_RS04840	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BWZ32_RS04845	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BWZ32_RS04860	COG0483	inositol monophosphate 1-phosphatase activity
BWZ32_RS04865	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
BWZ32_RS04870	COG1959	2 iron, 2 sulfur cluster binding
BWZ32_RS04880	COG0822	iron-sulfur transferase activity
BWZ32_RS04885	COG0316	Belongs to the HesB IscA family
BWZ32_RS04900	COG0633	Ferredoxin
BWZ32_RS04905	COG2975	iron-sulfur cluster assembly
BWZ32_RS04910	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BWZ32_RS04915	COG0105	UTP biosynthetic process
BWZ32_RS04920	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BWZ32_RS04935	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BWZ32_RS04940	COG0124	histidyl-tRNA synthetase
BWZ32_RS04945	COG2976	Protein conserved in bacteria
BWZ32_RS04950	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BWZ32_RS04955	COG1160	GTP binding
BWZ32_RS04965	COG2199	diguanylate cyclase activity
BWZ32_RS04965	COG2203	Gaf domain
BWZ32_RS04980	COG0516	GMP reductase activity
BWZ32_RS04980	COG0517	IMP dehydrogenase activity
BWZ32_RS04995	COG1584	GPR1 FUN34 yaaH family protein
BWZ32_RS05000	COG1115	amino acid carrier protein
BWZ32_RS05010	COG0583	DNA-binding transcription factor activity
BWZ32_RS05030	COG0009	L-threonylcarbamoyladenylate synthase
BWZ32_RS05080	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BWZ32_RS05085	COG2867	negative regulation of translational initiation
BWZ32_RS05090	COG2914	Belongs to the UPF0125 (RnfH) family
BWZ32_RS05095	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BWZ32_RS05100	COG0497	DNA recombination
BWZ32_RS05105	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BWZ32_RS05110	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BWZ32_RS05140	COG0443	Heat shock 70 kDa protein
BWZ32_RS05145	COG0484	heat shock protein binding
BWZ32_RS05155	COG4969	Belongs to the N-Me-Phe pilin family
BWZ32_RS05175	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
BWZ32_RS05180	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
BWZ32_RS05185	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
BWZ32_RS05190	COG0583	DNA-binding transcription factor activity
BWZ32_RS05205	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
BWZ32_RS05240	COG2195	Cleaves the N-terminal amino acid of tripeptides
BWZ32_RS05245	COG2252	PERMEase
BWZ32_RS05250	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
BWZ32_RS05255	COG1073	alpha beta
BWZ32_RS05265	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BWZ32_RS05270	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BWZ32_RS05275	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BWZ32_RS05280	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BWZ32_RS05280	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BWZ32_RS05295	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BWZ32_RS05300	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BWZ32_RS05305	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BWZ32_RS05310	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BWZ32_RS05315	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BWZ32_RS05320	COG0142	geranyltranstransferase activity
BWZ32_RS05325	COG1722	exodeoxyribonuclease VII activity
BWZ32_RS05330	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BWZ32_RS05345	COG0583	DNA-binding transcription factor activity
BWZ32_RS05355	COG2363	Small membrane protein
BWZ32_RS05375	COG1611	Belongs to the LOG family
BWZ32_RS05390	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BWZ32_RS05390	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BWZ32_RS05400	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
BWZ32_RS05405	COG1464	Belongs to the NlpA lipoprotein family
BWZ32_RS05410	COG2011	ABC-type metal ion transport system permease component
BWZ32_RS05420	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BWZ32_RS05430	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BWZ32_RS05430	COG1263	PTS System
BWZ32_RS05435	COG0366	Alpha amylase catalytic
BWZ32_RS05465	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BWZ32_RS05475	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BWZ32_RS05485	COG2921	Belongs to the UPF0250 family
BWZ32_RS05490	COG1686	Belongs to the peptidase S11 family
BWZ32_RS05495	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BWZ32_RS05500	COG0772	Belongs to the SEDS family
BWZ32_RS05510	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BWZ32_RS05515	COG0799	negative regulation of ribosome biogenesis
BWZ32_RS05520	COG1466	dna polymerase III delta subunit
BWZ32_RS05525	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
BWZ32_RS05535	COG2888	peptidyl-tyrosine sulfation
BWZ32_RS05540	COG0815	Transfers the fatty acyl group on membrane lipoproteins
BWZ32_RS05545	COG4535	Mg2 and Co2 transporter CorC
BWZ32_RS05550	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BWZ32_RS05555	COG1702	phosphate starvation-inducible protein PhoH
BWZ32_RS05565	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BWZ32_RS05655	COG0193	aminoacyl-tRNA hydrolase activity
BWZ32_RS05660	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BWZ32_RS05665	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BWZ32_RS05675	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BWZ32_RS05680	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BWZ32_RS05685	COG2890	protein-(glutamine-N5) methyltransferase activity
BWZ32_RS05695	COG2912	Transglutaminase-like superfamily
BWZ32_RS05700	COG2877	3-deoxy-8-phosphooctulonate synthase activity
BWZ32_RS05715	COG1187	pseudouridine synthase activity
BWZ32_RS05720	COG2840	Smr protein MutS2
BWZ32_RS05735	COG3735	TraB family
BWZ32_RS05750	COG2608	mercury ion transmembrane transporter activity
BWZ32_RS05750	COG2217	Heavy metal translocating P-type atpase
BWZ32_RS05810	COG0784	Response regulator, receiver
BWZ32_RS05810	COG0835	chemotaxis
BWZ32_RS05815	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BWZ32_RS05820	COG1815	bacterial-type flagellum-dependent cell motility
BWZ32_RS05835	COG1749	Flagellar hook protein flgE
BWZ32_RS05840	COG4787	bacterial-type flagellum-dependent cell motility
BWZ32_RS05855	COG1706	bacterial-type flagellum-dependent cell motility
BWZ32_RS05860	COG3951	Flagellar rod assembly protein muramidase FlgJ
BWZ32_RS05860	COG1705	Flagellar rod assembly protein muramidase FlgJ
BWZ32_RS05870	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BWZ32_RS05875	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BWZ32_RS05880	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BWZ32_RS05885	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BWZ32_RS05890	COG2190	(PTS) system
BWZ32_RS05895	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BWZ32_RS05900	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BWZ32_RS05905	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BWZ32_RS05910	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
BWZ32_RS05915	COG3115	cell septum assembly
BWZ32_RS05940	COG0330	HflC and HflK could
BWZ32_RS05945	COG3118	belongs to the thioredoxin family
BWZ32_RS05955	COG0300	oxidoreductase activity
BWZ32_RS05985	COG0622	Phosphoesterase
BWZ32_RS06005	COG3710	Transcriptional regulator
BWZ32_RS06010	COG0326	Molecular chaperone. Has ATPase activity
BWZ32_RS06025	COG0840	transmembrane signaling receptor activity
BWZ32_RS06030	COG3104	oligopeptide transport
BWZ32_RS06040	COG0367	asparagine synthase
BWZ32_RS06045	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BWZ32_RS06045	COG4651	solute:proton antiporter activity
BWZ32_RS06050	COG1846	Transcriptional regulator
BWZ32_RS06050	COG1940	carbohydrate kinase activity
BWZ32_RS06055	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BWZ32_RS06060	COG2190	(PTS) system
BWZ32_RS06060	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BWZ32_RS06060	COG1263	PTS System
BWZ32_RS06065	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BWZ32_RS06080	COG0716	FMN binding
BWZ32_RS06090	COG0596	Alpha beta hydrolase
BWZ32_RS06095	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
BWZ32_RS06100	COG0033	Phosphoglucomutase
BWZ32_RS06105	COG2964	Protein conserved in bacteria
BWZ32_RS06110	COG0251	oxidation-reduction process
BWZ32_RS06120	COG0446	pyridine nucleotide-disulphide oxidoreductase
BWZ32_RS06130	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BWZ32_RS06140	COG2009	succinate dehydrogenase
BWZ32_RS06145	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
BWZ32_RS06150	COG1053	succinate dehydrogenase
BWZ32_RS06160	COG0567	Dehydrogenase, E1 component
BWZ32_RS06165	COG0508	dehydrogenase complex catalyzes the overall conversion of
BWZ32_RS06180	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BWZ32_RS06185	COG1121	(ABC) transporter
BWZ32_RS06190	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
BWZ32_RS06200	COG1918	ferrous iron import across plasma membrane
BWZ32_RS06205	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BWZ32_RS06225	COG3102	Protein conserved in bacteria
BWZ32_RS06230	COG0788	formyltetrahydrofolate deformylase activity
BWZ32_RS06240	COG1199	ATP-dependent helicase activity
BWZ32_RS06245	COG1214	PFAM Peptidase M22, glycoprotease
BWZ32_RS06260	COG0596	Alpha beta hydrolase
BWZ32_RS06265	COG0318	PFAM AMP-dependent synthetase and ligase
BWZ32_RS06270	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
BWZ32_RS06275	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
BWZ32_RS06280	COG2894	cell division
BWZ32_RS06285	COG0850	regulation of cytokinetic process
BWZ32_RS06295	COG2951	lytic endotransglycosylase activity
BWZ32_RS06305	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BWZ32_RS06315	COG0745	RESPONSE REGULATOR receiver
BWZ32_RS06320	COG5002	protein histidine kinase activity
BWZ32_RS06335	COG1028	Short-chain dehydrogenase reductase Sdr
BWZ32_RS06345	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BWZ32_RS06370	COG2986	histidine ammonia-lyase
BWZ32_RS06375	COG1216	Glycosyl transferase, family 2
BWZ32_RS06385	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BWZ32_RS06395	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BWZ32_RS06400	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BWZ32_RS06445	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
BWZ32_RS06465	COG1175	transmembrane transport
BWZ32_RS06475	COG3842	ATPase activity
BWZ32_RS06480	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BWZ32_RS06485	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BWZ32_RS06490	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BWZ32_RS06500	COG2204	response regulator
BWZ32_RS06505	COG4191	Histidine kinase
BWZ32_RS06520	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BWZ32_RS06525	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BWZ32_RS06530	COG0776	regulation of translation
BWZ32_RS06535	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BWZ32_RS06540	COG1555	photosystem II stabilization
BWZ32_RS06555	COG0232	Belongs to the dGTPase family. Type 2 subfamily
BWZ32_RS06560	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
BWZ32_RS06565	COG0436	Aminotransferase
BWZ32_RS06570	COG1169	isochorismate synthase
BWZ32_RS06585	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BWZ32_RS06595	COG0318	PFAM AMP-dependent synthetase and ligase
BWZ32_RS06645	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BWZ32_RS06650	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BWZ32_RS06665	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BWZ32_RS06670	COG1522	sequence-specific DNA binding
BWZ32_RS06680	COG1946	Acyl-CoA thioesterase
BWZ32_RS06685	COG3126	Type III secretion system lipoprotein chaperone (YscW)
BWZ32_RS06700	COG5001	Diguanylate cyclase
BWZ32_RS06735	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BWZ32_RS06750	COG3139	Protein of unknown function (DUF1315)
BWZ32_RS06755	COG0252	asparaginase activity
BWZ32_RS06760	COG0616	signal peptide processing
BWZ32_RS06765	COG0446	pyridine nucleotide-disulphide oxidoreductase
BWZ32_RS06765	COG1902	pentaerythritol trinitrate reductase activity
BWZ32_RS06770	COG0778	Nitroreductase
BWZ32_RS06775	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BWZ32_RS06780	COG0123	including yeast histone deacetylase and acetoin utilization protein
BWZ32_RS06785	COG0784	Response regulator, receiver
BWZ32_RS06785	COG2205	protein histidine kinase activity
BWZ32_RS06795	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BWZ32_RS06800	COG2731	YhcH YjgK YiaL family protein
BWZ32_RS06805	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BWZ32_RS06810	COG0569	domain protein
BWZ32_RS06820	COG3083	sulfuric ester hydrolase activity
BWZ32_RS06830	COG3081	Nucleoid-associated protein
BWZ32_RS06845	COG1757	Na H antiporter
BWZ32_RS06850	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BWZ32_RS06860	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BWZ32_RS06865	COG2095	MarC family integral membrane protein
BWZ32_RS06870	COG1012	belongs to the aldehyde dehydrogenase family
BWZ32_RS06870	COG1454	alcohol dehydrogenase
BWZ32_RS06875	COG1028	Short-chain dehydrogenase reductase Sdr
BWZ32_RS06890	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BWZ32_RS06900	COG2056	Na+-H+ antiporter family
BWZ32_RS06905	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BWZ32_RS06910	COG2885	chlorophyll binding
BWZ32_RS06920	COG0346	lactoylglutathione lyase activity
BWZ32_RS06925	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BWZ32_RS06930	COG4660	Part of a membrane complex involved in electron transport
BWZ32_RS06935	COG4659	FMN binding
BWZ32_RS06940	COG4658	electron transport chain
BWZ32_RS06945	COG4656	Part of a membrane complex involved in electron transport
BWZ32_RS06950	COG2878	Part of a membrane complex involved in electron transport
BWZ32_RS06955	COG4657	Part of a membrane complex involved in electron transport
BWZ32_RS06970	COG0556	nucleotide-excision repair
BWZ32_RS06975	COG2204	response regulator
BWZ32_RS06980	COG2198	Histidine kinase
BWZ32_RS06985	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BWZ32_RS06995	COG0521	Mo-molybdopterin cofactor biosynthetic process
BWZ32_RS07005	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BWZ32_RS07010	COG0314	molybdopterin synthase activity
BWZ32_RS07020	COG0601	transmembrane transport
BWZ32_RS07025	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BWZ32_RS07030	COG0444	Belongs to the ABC transporter superfamily
BWZ32_RS07040	COG0435	Glutathione S-transferase
BWZ32_RS07050	COG2350	Protein conserved in bacteria
BWZ32_RS07070	COG1301	dicarboxylic acid transport
BWZ32_RS07080	COG0133	tryptophan synthase activity
BWZ32_RS07085	COG0134	indole-3-glycerol-phosphate synthase activity
BWZ32_RS07085	COG0135	phosphoribosylanthranilate isomerase activity
BWZ32_RS07095	COG0512	Glutamine amidotransferase of anthranilate synthase
BWZ32_RS07100	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BWZ32_RS07110	COG0613	PHP domain protein
BWZ32_RS07115	COG0009	L-threonylcarbamoyladenylate synthase
BWZ32_RS07135	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BWZ32_RS07145	COG5001	Diguanylate cyclase
BWZ32_RS07150	COG0417	DNA replication proofreading
BWZ32_RS07155	COG2197	response regulator
BWZ32_RS07225	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BWZ32_RS07230	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BWZ32_RS07235	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BWZ32_RS07260	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
BWZ32_RS07265	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
BWZ32_RS07270	COG0437	4 iron, 4 sulfur cluster binding
BWZ32_RS07275	COG3301	Polysulphide reductase, NrfD
BWZ32_RS07280	COG1138	Cytochrome C-type biogenesis protein
BWZ32_RS07285	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BWZ32_RS07290	COG3088	subunit of a heme lyase
BWZ32_RS07290	COG4235	cytochrome complex assembly
BWZ32_RS07300	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BWZ32_RS07300	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BWZ32_RS07305	COG0489	protein tyrosine kinase activity
BWZ32_RS07310	COG0572	uridine kinase
BWZ32_RS07320	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
BWZ32_RS07325	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BWZ32_RS07330	COG0659	secondary active sulfate transmembrane transporter activity
BWZ32_RS07335	COG1530	ribonuclease E activity
BWZ32_RS07345	COG0424	maF-like protein
BWZ32_RS07350	COG1399	metal-binding, possibly nucleic acid-binding protein
BWZ32_RS07355	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BWZ32_RS07360	COG0416	fatty acid biosynthetic process
BWZ32_RS07365	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BWZ32_RS07380	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BWZ32_RS07395	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BWZ32_RS07400	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BWZ32_RS07410	COG0084	hydrolase, TatD family'
BWZ32_RS07415	COG1263	PTS System
BWZ32_RS07415	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BWZ32_RS07425	COG0733	neurotransmitter:sodium symporter activity
BWZ32_RS07440	COG4667	esterase of the alpha-beta hydrolase superfamily
BWZ32_RS07445	COG0469	pyruvate kinase activity
BWZ32_RS07450	COG1940	carbohydrate kinase activity
BWZ32_RS07455	COG0835	chemotaxis
BWZ32_RS07455	COG0784	Response regulator, receiver
BWZ32_RS07475	COG1028	Short-chain dehydrogenase reductase Sdr
BWZ32_RS07480	COG0616	signal peptide processing
BWZ32_RS07490	COG0539	negative regulation of cytoplasmic translation
BWZ32_RS07500	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
BWZ32_RS07505	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
BWZ32_RS07510	COG0284	orotidine-5'-phosphate decarboxylase activity
BWZ32_RS07515	COG4174	ABC transporter (Permease)
BWZ32_RS07520	COG4239	(ABC) transporter, permease
BWZ32_RS07525	COG4166	transmembrane transport
BWZ32_RS07530	COG0444	Belongs to the ABC transporter superfamily
BWZ32_RS07535	COG4608	Belongs to the ABC transporter superfamily
BWZ32_RS07575	COG2989	Protein conserved in bacteria
BWZ32_RS07580	COG3108	Peptidase M15
BWZ32_RS07585	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BWZ32_RS07615	COG0583	DNA-binding transcription factor activity
BWZ32_RS07625	COG0686	Belongs to the AlaDH PNT family
BWZ32_RS07640	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BWZ32_RS07645	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BWZ32_RS07660	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BWZ32_RS07670	COG2226	methyltransferase
BWZ32_RS07675	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BWZ32_RS07680	COG0501	Belongs to the peptidase M48B family
BWZ32_RS07690	COG0300	oxidoreductase activity
BWZ32_RS07705	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BWZ32_RS07725	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BWZ32_RS07730	COG2915	High frequency lysogenization protein hflD homolog
BWZ32_RS07735	COG0482	sulfurtransferase activity
BWZ32_RS07745	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BWZ32_RS07750	COG2916	Histone family protein nucleoid-structuring protein H-NS
BWZ32_RS07755	COG1757	Na H antiporter
BWZ32_RS07760	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BWZ32_RS07770	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BWZ32_RS07775	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BWZ32_RS07775	COG0131	Imidazoleglycerol-phosphate dehydratase
BWZ32_RS07780	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BWZ32_RS07785	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BWZ32_RS07790	COG0107	imidazoleglycerol-phosphate synthase activity
BWZ32_RS07795	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BWZ32_RS07795	COG0140	phosphoribosyl-ATP diphosphatase activity
BWZ32_RS07805	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
BWZ32_RS07810	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BWZ32_RS07815	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BWZ32_RS07825	COG1435	thymidine kinase activity
BWZ32_RS07835	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BWZ32_RS07840	COG0583	DNA-binding transcription factor activity
BWZ32_RS07860	COG2116	formate transmembrane transporter activity
BWZ32_RS07865	COG0390	transport system, permease component
BWZ32_RS07870	COG4459	periplasmic nitrate reductase
BWZ32_RS07875	COG3005	denitrification pathway
BWZ32_RS07910	COG1227	inorganic diphosphatase activity
BWZ32_RS07925	COG4172	Belongs to the ABC transporter superfamily
BWZ32_RS07935	COG4171	peptide transport system, permease
BWZ32_RS07950	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BWZ32_RS07955	COG1842	Phage shock protein A
BWZ32_RS07965	COG1983	PspC domain protein
BWZ32_RS07985	COG2818	Glycosylase
BWZ32_RS07990	COG0626	cystathionine gamma-synthase activity
BWZ32_RS08000	COG0733	neurotransmitter:sodium symporter activity
BWZ32_RS08010	COG0564	pseudouridine synthase activity
BWZ32_RS08020	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BWZ32_RS08025	COG1151	hydroxylamine reductase activity
BWZ32_RS08030	COG3604	Transcriptional regulator
BWZ32_RS08035	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BWZ32_RS08040	COG4136	ATPase activity
BWZ32_RS08045	COG4135	transport system, permease component
BWZ32_RS08050	COG4134	Bacterial extracellular solute-binding protein
BWZ32_RS08060	COG3313	Fe-S protein
BWZ32_RS08090	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BWZ32_RS08095	COG2205	protein histidine kinase activity
BWZ32_RS08110	COG1061	Type III restriction enzyme res subunit
BWZ32_RS08120	COG2814	Major facilitator Superfamily
BWZ32_RS08135	COG0702	epimerase
BWZ32_RS08140	COG1136	(ABC) transporter
BWZ32_RS08155	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BWZ32_RS08175	COG2985	domain, Protein
BWZ32_RS08175	COG3273	potassium ion transport
BWZ32_RS08180	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BWZ32_RS08185	COG1979	alcohol dehydrogenase
BWZ32_RS08190	COG1737	Transcriptional regulator
BWZ32_RS08195	COG0076	glutamate decarboxylase activity
BWZ32_RS08205	COG2431	L-lysine efflux transmembrane transporter activity
BWZ32_RS08215	COG3070	regulator of competence-specific genes
BWZ32_RS08230	COG5002	protein histidine kinase activity
BWZ32_RS08230	COG5002	protein histidine kinase activity
BWZ32_RS08240	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BWZ32_RS08245	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BWZ32_RS08250	COG4988	ABC transporter
BWZ32_RS08255	COG0492	ferredoxin-NADP+ reductase activity
BWZ32_RS08280	COG0471	metal ion transport
BWZ32_RS08285	COG2949	membrane
BWZ32_RS08290	COG0281	malic enzyme
BWZ32_RS08295	COG1643	Atp-dependent helicase
BWZ32_RS08310	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BWZ32_RS08320	COG1346	cytolysis
BWZ32_RS08325	COG1380	Effector of murein hydrolase LrgA
BWZ32_RS08330	COG2925	Exonuclease
BWZ32_RS08345	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
BWZ32_RS08365	COG2988	succinylglutamate desuccinylase activity
BWZ32_RS08375	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
BWZ32_RS08395	COG0583	DNA-binding transcription factor activity
BWZ32_RS08405	COG1451	nucleotide metabolic process
BWZ32_RS08420	COG3063	Type IV pilus biogenesis stability protein PilW
BWZ32_RS08435	COG2195	Cleaves the N-terminal amino acid of tripeptides
BWZ32_RS08445	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
BWZ32_RS08455	COG0625	glutathione transferase activity
BWZ32_RS08495	COG1278	Cold shock
BWZ32_RS08510	COG0584	glycerophosphoryl diester phosphodiesterase
BWZ32_RS08515	COG1349	DNA-binding transcription factor activity
BWZ32_RS08525	COG0395	ABC-type sugar transport system, permease component
BWZ32_RS08530	COG1175	transmembrane transport
BWZ32_RS08535	COG1653	transport
BWZ32_RS08550	COG0730	response to heat
BWZ32_RS08560	COG2197	response regulator
BWZ32_RS08600	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BWZ32_RS08610	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BWZ32_RS08615	COG0372	Belongs to the citrate synthase family
BWZ32_RS08625	COG2828	Protein conserved in bacteria
BWZ32_RS08655	COG0561	phosphatase activity
BWZ32_RS08660	COG0602	queuosine metabolic process
BWZ32_RS08665	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BWZ32_RS08670	COG3706	GGDEF domain
BWZ32_RS08700	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BWZ32_RS08710	COG1254	Belongs to the acylphosphatase family
BWZ32_RS08715	COG2920	part of a sulfur-relay system
BWZ32_RS08725	COG0670	Belongs to the BI1 family
BWZ32_RS08730	COG1126	abc transporter atp-binding protein
BWZ32_RS08735	COG0765	amino acid transport
BWZ32_RS08740	COG4597	amino acid ABC transporter
BWZ32_RS08745	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BWZ32_RS08755	COG0437	4 iron, 4 sulfur cluster binding
BWZ32_RS08760	COG0348	domain, Protein
BWZ32_RS08765	COG0204	Acyl-transferase
BWZ32_RS08770	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BWZ32_RS08785	COG1115	amino acid carrier protein
BWZ32_RS08810	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BWZ32_RS08825	COG3290	protein histidine kinase activity
BWZ32_RS08830	COG4565	transcriptional regulatory protein
BWZ32_RS08835	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BWZ32_RS08840	COG0363	glucosamine-6-phosphate deaminase activity
BWZ32_RS08845	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BWZ32_RS08880	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BWZ32_RS08890	COG0438	transferase activity, transferring glycosyl groups
BWZ32_RS08935	COG2204	response regulator
BWZ32_RS08965	COG1366	Belongs to the anti-sigma-factor antagonist family
BWZ32_RS08970	COG1793	dna ligase
BWZ32_RS08975	COG3706	GGDEF domain
BWZ32_RS08985	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BWZ32_RS09000	COG2996	Protein conserved in bacteria
BWZ32_RS09005	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BWZ32_RS09005	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
BWZ32_RS09010	COG3008	intermembrane lipid transfer
BWZ32_RS09015	COG2995	paraquat-inducible protein a
BWZ32_RS09020	COG1132	(ABC) transporter
BWZ32_RS09025	COG1956	GAF domain-containing protein
BWZ32_RS09030	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
BWZ32_RS09045	COG0308	aminopeptidase N
BWZ32_RS09055	COG2902	Dehydrogenase
BWZ32_RS09060	COG0167	dihydroorotate dehydrogenase activity
BWZ32_RS09070	COG0116	Belongs to the methyltransferase superfamily
BWZ32_RS09070	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BWZ32_RS09080	COG0488	(ABC) transporter
BWZ32_RS09095	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BWZ32_RS09100	COG1067	ATP-dependent peptidase activity
BWZ32_RS09105	COG3120	sequence-specific DNA binding
BWZ32_RS09125	COG0784	Response regulator, receiver
BWZ32_RS09125	COG2205	protein histidine kinase activity
BWZ32_RS09140	COG3278	Belongs to the heme-copper respiratory oxidase family
BWZ32_RS09155	COG2010	Cytochrome c
BWZ32_RS09165	COG2217	Heavy metal translocating P-type atpase
BWZ32_RS09180	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BWZ32_RS09185	COG0589	response to stress
BWZ32_RS09190	COG0037	tRNA processing
BWZ32_RS09200	COG2992	FlgJ-related protein
BWZ32_RS09210	COG3842	ATPase activity
BWZ32_RS09215	COG1176	ABC-type spermidine putrescine transport system, permease component I
BWZ32_RS09220	COG1177	transmembrane transport
BWZ32_RS09230	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BWZ32_RS09235	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BWZ32_RS09240	COG0004	ammonium transporteR
BWZ32_RS09275	COG0437	4 iron, 4 sulfur cluster binding
BWZ32_RS09280	COG3383	formate dehydrogenase (NAD+) activity
BWZ32_RS09280	COG0243	molybdopterin cofactor binding
BWZ32_RS09310	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BWZ32_RS09320	COG0488	(ABC) transporter
BWZ32_RS09335	COG3852	Histidine kinase
BWZ32_RS09340	COG2204	response regulator
BWZ32_RS09350	COG4662	Binding-protein-dependent transport system inner membrane component
BWZ32_RS09355	COG3842	ATPase activity
BWZ32_RS09375	COG1940	carbohydrate kinase activity
BWZ32_RS09380	COG3148	PFAM DTW domain containing protein
BWZ32_RS09390	COG0840	transmembrane signaling receptor activity
BWZ32_RS09395	COG0791	NLP P60 protein
BWZ32_RS09405	COG3706	GGDEF domain
BWZ32_RS09425	COG0307	riboflavin synthase, alpha
BWZ32_RS09430	COG0534	Mate efflux family protein
BWZ32_RS09465	COG2801	Transposase and inactivated derivatives
BWZ32_RS09505	COG0384	phenazine biosynthesis protein PhzF
BWZ32_RS09780	COG1028	Short-chain dehydrogenase reductase Sdr
BWZ32_RS09790	COG0346	lactoylglutathione lyase activity
BWZ32_RS10180	COG3738	Protein conserved in bacteria
BWZ32_RS10220	COG1942	4-Oxalocrotonate Tautomerase
BWZ32_RS10700	COG4115	mRNA cleavage
BWZ32_RS10705	COG2161	toxin-antitoxin pair type II binding
BWZ32_RS10785	COG4628	conserved protein (DUF2132)
BWZ32_RS11405	COG4628	conserved protein (DUF2132)
BWZ32_RS11555	COG1011	Hydrolase
BWZ32_RS11635	COG1028	Short-chain dehydrogenase reductase Sdr
BWZ32_RS11655	COG1028	Short-chain dehydrogenase reductase Sdr
BWZ32_RS11660	COG0456	acetyltransferase
BWZ32_RS11685	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BWZ32_RS11710	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BWZ32_RS11730	COG4326	sporulation control protein
BWZ32_RS11755	COG2986	histidine ammonia-lyase
BWZ32_RS11765	COG5640	endopeptidase activity
BWZ32_RS11770	COG2020	methyltransferase activity
BWZ32_RS11775	COG0247	lactate metabolic process
BWZ32_RS11775	COG0277	FAD linked oxidase domain protein
BWZ32_RS11790	COG2885	chlorophyll binding
BWZ32_RS11810	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
BWZ32_RS11815	COG0500	methyltransferase
BWZ32_RS11825	COG0776	regulation of translation
BWZ32_RS11845	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BWZ32_RS11845	COG0072	phenylalanine-tRNA ligase activity
BWZ32_RS11850	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BWZ32_RS11915	COG1166	arginine decarboxylase activity
BWZ32_RS11920	COG0010	Belongs to the arginase family
BWZ32_RS11925	COG0840	transmembrane signaling receptor activity
BWZ32_RS11940	COG2814	Major facilitator Superfamily
BWZ32_RS11955	COG3279	Response regulator of the LytR AlgR family
BWZ32_RS11960	COG5380	lipid catabolic process
BWZ32_RS11965	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
BWZ32_RS11990	COG1643	Atp-dependent helicase
BWZ32_RS12005	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BWZ32_RS12045	COG2894	cell division
BWZ32_RS12055	COG4964	Belongs to the GSP D family
BWZ32_RS12085	COG3713	MltA-interacting MipA family protein
BWZ32_RS12105	COG3706	GGDEF domain
BWZ32_RS12115	COG0443	Heat shock 70 kDa protein
BWZ32_RS12120	COG0443	Heat shock 70 kDa protein
BWZ32_RS12145	COG2165	general secretion pathway protein
BWZ32_RS12160	COG0438	transferase activity, transferring glycosyl groups
BWZ32_RS12160	COG0297	glycogen (starch) synthase activity
BWZ32_RS12165	COG0438	transferase activity, transferring glycosyl groups
BWZ32_RS12190	COG1596	polysaccharide export
BWZ32_RS12200	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BWZ32_RS12205	COG1115	amino acid carrier protein
BWZ32_RS12210	COG1132	(ABC) transporter
BWZ32_RS12215	COG1132	(ABC) transporter
BWZ32_RS12230	COG0783	Belongs to the Dps family
BWZ32_RS12245	COG0814	amino acid
BWZ32_RS12250	COG1597	lipid kinase activity
BWZ32_RS12260	COG4667	esterase of the alpha-beta hydrolase superfamily
BWZ32_RS12265	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BWZ32_RS12280	COG0583	DNA-binding transcription factor activity
BWZ32_RS12290	COG1328	CTP reductase activity
BWZ32_RS12295	COG5001	Diguanylate cyclase
BWZ32_RS12295	COG3300	MHYT domain
BWZ32_RS12310	COG2199	diguanylate cyclase activity
BWZ32_RS12310	COG2200	EAL domain
BWZ32_RS12315	COG3706	GGDEF domain
BWZ32_RS12325	COG4191	Histidine kinase
BWZ32_RS12325	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BWZ32_RS12330	COG0471	metal ion transport
BWZ32_RS12345	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BWZ32_RS12350	COG3283	Transcriptional regulator of aromatic amino acids metabolism
BWZ32_RS12355	COG3768	UPF0283 membrane protein
BWZ32_RS12360	COG3106	COG3106 Predicted ATPase
BWZ32_RS12375	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BWZ32_RS12385	COG2205	protein histidine kinase activity
BWZ32_RS12385	COG0784	Response regulator, receiver
BWZ32_RS12395	COG0494	nUDIX hydrolase
BWZ32_RS12400	COG0814	amino acid
BWZ32_RS12405	COG1760	l-serine dehydratase
BWZ32_RS12410	COG2200	EAL domain
BWZ32_RS12420	COG0720	synthase
BWZ32_RS12425	COG0840	transmembrane signaling receptor activity
BWZ32_RS12430	COG0017	Asparaginyl-tRNA synthetase
BWZ32_RS12440	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BWZ32_RS12455	COG3437	response regulator, receiver
BWZ32_RS12455	COG2770	Histidine kinase
BWZ32_RS12460	COG1448	Aminotransferase
BWZ32_RS12480	COG0840	transmembrane signaling receptor activity
BWZ32_RS12485	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BWZ32_RS12490	COG1846	Transcriptional regulator
BWZ32_RS12515	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BWZ32_RS12530	COG2186	Transcriptional regulator
BWZ32_RS12535	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BWZ32_RS12545	COG0653	protein targeting
BWZ32_RS12560	COG0366	Alpha amylase catalytic
BWZ32_RS12570	COG4120	Belongs to the binding-protein-dependent transport system permease family
BWZ32_RS12580	COG3092	negative regulation of chromosome organization
BWZ32_RS12585	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BWZ32_RS12590	COG0857	belongs to the CobB CobQ family
BWZ32_RS12590	COG0280	phosphate acetyltransferase
BWZ32_RS12600	COG0583	DNA-binding transcription factor activity
BWZ32_RS12645	COG2207	Transcriptional regulator
BWZ32_RS12670	COG0861	Integral membrane protein TerC family
BWZ32_RS12675	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BWZ32_RS12680	COG1454	alcohol dehydrogenase
BWZ32_RS12685	COG0235	Class ii aldolase
BWZ32_RS12690	COG4154	Belongs to the RbsD FucU family
BWZ32_RS12695	COG1070	Carbohydrate kinase
BWZ32_RS12700	COG2407	Converts the aldose L-fucose into the corresponding ketose L-fuculose
BWZ32_RS12705	COG0738	Major facilitator superfamily
BWZ32_RS12710	COG1349	DNA-binding transcription factor activity
BWZ32_RS12715	COG0840	transmembrane signaling receptor activity
BWZ32_RS12720	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BWZ32_RS12735	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BWZ32_RS12780	COG1111	helicase
BWZ32_RS12780	COG1205	dead DEAH box helicase
BWZ32_RS12790	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BWZ32_RS12850	COG0582	viral genome integration into host DNA
BWZ32_RS12865	COG2205	protein histidine kinase activity
BWZ32_RS12865	COG0784	Response regulator, receiver
BWZ32_RS12875	COG0754	glutathionylspermidine amidase activity
BWZ32_RS12885	COG3766	membrane
BWZ32_RS12895	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BWZ32_RS12900	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
BWZ32_RS12905	COG2885	chlorophyll binding
BWZ32_RS12910	COG0823	Involved in the tonB-independent uptake of proteins
BWZ32_RS12925	COG0811	peptide transport
BWZ32_RS12930	COG0824	Thioesterase
BWZ32_RS12940	COG4890	Cyd operon protein YbgT
BWZ32_RS12945	COG1294	oxidase, subunit
BWZ32_RS12950	COG1271	oxidase subunit
BWZ32_RS12955	COG2255	four-way junction helicase activity
BWZ32_RS12960	COG0632	four-way junction helicase activity
BWZ32_RS12965	COG0840	transmembrane signaling receptor activity
BWZ32_RS12985	COG4106	trans-aconitate 2-methyltransferase activity
BWZ32_RS12990	COG0500	methyltransferase
BWZ32_RS12995	COG4067	protein conserved in archaea
BWZ32_RS12995	COG0189	ligase activity
BWZ32_RS13030	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
BWZ32_RS13035	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
BWZ32_RS13040	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BWZ32_RS13045	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BWZ32_RS13050	COG0745	RESPONSE REGULATOR receiver
BWZ32_RS13055	COG3381	protein complex oligomerization
BWZ32_RS13060	COG1609	Transcriptional regulator
BWZ32_RS13065	COG3070	regulator of competence-specific genes
BWZ32_RS13085	COG0297	glycogen (starch) synthase activity
BWZ32_RS13090	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BWZ32_RS13100	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BWZ32_RS13110	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BWZ32_RS13125	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
BWZ32_RS13130	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BWZ32_RS13135	COG0542	response to heat
BWZ32_RS13140	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
BWZ32_RS13145	COG1278	Cold shock
BWZ32_RS13165	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BWZ32_RS13170	COG1199	ATP-dependent helicase activity
BWZ32_RS13180	COG3923	Primosomal replication protein n
BWZ32_RS13190	COG0840	transmembrane signaling receptor activity
BWZ32_RS13195	COG0708	Exodeoxyribonuclease III
BWZ32_RS13235	COG1882	Formate acetyltransferase
BWZ32_RS13250	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BWZ32_RS13260	COG3013	Belongs to the UPF0304 family
BWZ32_RS13265	COG2766	serine protein kinase
BWZ32_RS13270	COG2718	Belongs to the UPF0229 family
BWZ32_RS13275	COG2719	SpoVR family
BWZ32_RS13280	COG2199	diguanylate cyclase activity
BWZ32_RS13285	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
BWZ32_RS13290	COG2835	tetraacyldisaccharide 4'-kinase activity
BWZ32_RS13295	COG1663	tetraacyldisaccharide 4'-kinase activity
BWZ32_RS13300	COG1132	(ABC) transporter
BWZ32_RS13305	COG2333	competence protein COMEC
BWZ32_RS13305	COG0658	competence protein
BWZ32_RS13315	COG4591	ABC-type transport system involved in lipoprotein release permease component
BWZ32_RS13320	COG1136	(ABC) transporter
BWZ32_RS13325	COG4591	ABC-type transport system involved in lipoprotein release permease component
BWZ32_RS13335	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BWZ32_RS13350	COG1252	NADH dehydrogenase
BWZ32_RS13380	COG0537	adenosine 5'-monophosphoramidase activity
BWZ32_RS13405	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BWZ32_RS13405	COG0517	IMP dehydrogenase activity
BWZ32_RS13405	COG0617	tRNA 3'-terminal CCA addition
BWZ32_RS13410	COG3706	GGDEF domain
BWZ32_RS13415	COG1982	Orn Lys Arg decarboxylase major
BWZ32_RS13420	COG0531	amino acid
BWZ32_RS13430	COG3710	Transcriptional regulator
BWZ32_RS13450	COG2199	diguanylate cyclase activity
BWZ32_RS13450	COG2203	Gaf domain
BWZ32_RS13455	COG2239	Acts as a magnesium transporter
BWZ32_RS13465	COG3550	peptidyl-serine autophosphorylation
BWZ32_RS13470	COG1396	sequence-specific DNA binding
BWZ32_RS13590	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BWZ32_RS13595	COG2226	methyltransferase
BWZ32_RS13610	COG1785	Belongs to the alkaline phosphatase family
BWZ32_RS13620	COG0346	lactoylglutathione lyase activity
BWZ32_RS13630	COG2983	Belongs to the UPF0260 family
BWZ32_RS13645	COG0745	RESPONSE REGULATOR receiver
BWZ32_RS13650	COG2205	protein histidine kinase activity
BWZ32_RS13665	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BWZ32_RS13670	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BWZ32_RS13680	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BWZ32_RS13685	COG2832	Protein of unknown function (DUF454)
BWZ32_RS13695	COG0745	RESPONSE REGULATOR receiver
BWZ32_RS13700	COG0583	DNA-binding transcription factor activity
BWZ32_RS13705	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BWZ32_RS13710	COG1286	toxin biosynthetic process
BWZ32_RS13715	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
BWZ32_RS13720	COG0285	dihydrofolate synthase activity
BWZ32_RS13725	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BWZ32_RS13730	COG0101	tRNA pseudouridine synthase activity
BWZ32_RS13740	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BWZ32_RS13755	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BWZ32_RS13775	COG2860	membrane
BWZ32_RS13780	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BWZ32_RS13785	COG2890	protein-(glutamine-N5) methyltransferase activity
BWZ32_RS13790	COG2840	Smr protein MutS2
BWZ32_RS13795	COG2062	phosphohistidine phosphatase, SixA
BWZ32_RS13805	COG1025	Belongs to the peptidase M16 family
BWZ32_RS13830	COG2067	long-chain fatty acid transport protein
BWZ32_RS13835	COG2067	long-chain fatty acid transport protein
BWZ32_RS13840	COG2853	Lipoprotein
BWZ32_RS13850	COG4235	cytochrome complex assembly
BWZ32_RS13850	COG3088	subunit of a heme lyase
BWZ32_RS13855	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BWZ32_RS13860	COG1138	Cytochrome C-type biogenesis protein
BWZ32_RS13865	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
BWZ32_RS13870	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BWZ32_RS13875	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BWZ32_RS13880	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BWZ32_RS13885	COG4133	protoheme IX ABC transporter activity
BWZ32_RS13895	COG0835	chemotaxis
BWZ32_RS13905	COG1192	Involved in chromosome partitioning
BWZ32_RS13910	COG2201	protein-glutamate methylesterase activity
BWZ32_RS13915	COG2198	Histidine kinase
BWZ32_RS13915	COG0643	Histidine kinase
BWZ32_RS13915	COG0784	Response regulator, receiver
BWZ32_RS13920	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
BWZ32_RS13955	COG1684	flagellar biosynthetic protein fliR
BWZ32_RS13960	COG1987	bacterial-type flagellum assembly
BWZ32_RS14010	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BWZ32_RS14020	COG1677	Flagellar hook-basal body complex protein FliE
BWZ32_RS14040	COG1516	flagellar protein fliS
BWZ32_RS14050	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BWZ32_RS14055	COG1334	flagellar protein FlaG
BWZ32_RS14060	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BWZ32_RS14065	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BWZ32_RS14070	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BWZ32_RS14075	COG2837	iron assimilation
BWZ32_RS14100	COG1393	Belongs to the ArsC family
BWZ32_RS14120	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
BWZ32_RS14125	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BWZ32_RS14130	COG2716	regulation of RNA biosynthetic process
BWZ32_RS14135	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BWZ32_RS14150	COG4783	chaperone-mediated protein folding
BWZ32_RS14155	COG1393	Belongs to the ArsC family
BWZ32_RS14175	COG2233	PERMEase
BWZ32_RS14180	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BWZ32_RS14185	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BWZ32_RS14190	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BWZ32_RS14195	COG0121	glutamine amidotransferase
BWZ32_RS14205	COG1960	acyl-CoA dehydrogenase activity
BWZ32_RS14235	COG2249	NAD(P)H dehydrogenase (quinone) activity
BWZ32_RS14250	COG0328	RNA-DNA hybrid ribonuclease activity
BWZ32_RS14255	COG2226	methyltransferase
BWZ32_RS14260	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BWZ32_RS14265	COG1388	LysM domain
BWZ32_RS14265	COG0741	lytic transglycosylase activity
BWZ32_RS14275	COG3021	interspecies interaction between organisms
BWZ32_RS14280	COG0347	Belongs to the P(II) protein family
BWZ32_RS14295	COG0825	malonyl-CoA metabolic process
BWZ32_RS14300	COG0587	DNA-directed DNA polymerase activity
BWZ32_RS14305	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BWZ32_RS14310	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BWZ32_RS14315	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BWZ32_RS14320	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BWZ32_RS14325	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BWZ32_RS14330	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
BWZ32_RS14335	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BWZ32_RS14340	COG0750	zinc metalloprotease
BWZ32_RS14345	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BWZ32_RS14350	COG0575	Belongs to the CDS family
BWZ32_RS14355	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BWZ32_RS14360	COG0233	cytoplasmic translational termination
BWZ32_RS14365	COG0528	UMP kinase activity
BWZ32_RS14370	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BWZ32_RS14375	COG0052	Belongs to the universal ribosomal protein uS2 family
BWZ32_RS14380	COG0024	Methionine aminopeptidase
BWZ32_RS14385	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
BWZ32_RS14400	COG3098	single-species biofilm formation
BWZ32_RS14440	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BWZ32_RS14460	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
BWZ32_RS14470	COG0254	rRNA binding
BWZ32_RS14475	COG1720	tRNA m6t6A37 methyltransferase activity
BWZ32_RS14500	COG0733	neurotransmitter:sodium symporter activity
BWZ32_RS14515	COG0514	ATP-dependent DNA helicase (RecQ)
BWZ32_RS14520	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BWZ32_RS14535	COG1477	protein flavinylation
BWZ32_RS14540	COG2871	sodium ion transport
BWZ32_RS14545	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BWZ32_RS14555	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BWZ32_RS14560	COG1805	sodium ion transport
BWZ32_RS14565	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BWZ32_RS14570	COG0271	Belongs to the BolA IbaG family
BWZ32_RS14575	COG2813	Specifically methylates the guanine in position
BWZ32_RS14590	COG2211	Major facilitator Superfamily
BWZ32_RS14600	COG1595	DNA-templated transcription, initiation
BWZ32_RS14615	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BWZ32_RS14620	COG0693	protein deglycase activity
BWZ32_RS14625	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BWZ32_RS14645	COG0840	transmembrane signaling receptor activity
BWZ32_RS14650	COG2166	iron-sulfur cluster assembly
BWZ32_RS14655	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BWZ32_RS14660	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
BWZ32_RS14680	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BWZ32_RS14685	COG1074	ATP-dependent DNA helicase activity
BWZ32_RS14690	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
BWZ32_RS14695	COG3083	sulfuric ester hydrolase activity
BWZ32_RS14710	COG3141	response to X-ray
BWZ32_RS14715	COG2171	N-acyltransferase activity
BWZ32_RS14720	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BWZ32_RS14725	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BWZ32_RS14730	COG1349	DNA-binding transcription factor activity
BWZ32_RS14735	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BWZ32_RS14750	COG0189	ligase activity
BWZ32_RS14750	COG0569	domain protein
BWZ32_RS14770	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BWZ32_RS14780	COG0840	transmembrane signaling receptor activity
BWZ32_RS14785	COG2017	converts alpha-aldose to the beta-anomer
BWZ32_RS14800	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BWZ32_RS14805	COG1609	Transcriptional regulator
BWZ32_RS14815	COG3250	beta-galactosidase activity
BWZ32_RS14820	COG2731	YhcH YjgK YiaL family protein
BWZ32_RS14825	COG0531	amino acid
BWZ32_RS14830	COG0531	amino acid
BWZ32_RS14835	COG3408	Glycogen debranching enzyme
BWZ32_RS14835	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
BWZ32_RS14845	COG0583	DNA-binding transcription factor activity
BWZ32_RS14850	COG2059	Chromate
BWZ32_RS14900	COG4964	Belongs to the GSP D family
BWZ32_RS14935	COG1022	Amp-dependent synthetase and ligase
BWZ32_RS14945	COG0583	DNA-binding transcription factor activity
BWZ32_RS14950	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BWZ32_RS14970	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BWZ32_RS14980	COG0560	Phosphoserine phosphatase
BWZ32_RS14990	COG0813	purine-nucleoside phosphorylase activity
BWZ32_RS14995	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
BWZ32_RS15000	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BWZ32_RS15005	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BWZ32_RS15010	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BWZ32_RS15015	COG0084	hydrolase, TatD family'
BWZ32_RS15025	COG3706	GGDEF domain
BWZ32_RS15035	COG0456	acetyltransferase
BWZ32_RS15045	COG3153	acetyltransferase
BWZ32_RS15050	COG3154	lipid carrier protein
BWZ32_RS15060	COG0826	peptidase U32
BWZ32_RS15065	COG0826	peptidase U32
BWZ32_RS15070	COG0534	Mate efflux family protein
BWZ32_RS15085	COG1185	polyribonucleotide nucleotidyltransferase activity
BWZ32_RS15120	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BWZ32_RS15125	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BWZ32_RS15130	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BWZ32_RS15140	COG0195	Participates in both transcription termination and antitermination
BWZ32_RS15145	COG0779	Required for maturation of 30S ribosomal subunits
BWZ32_RS15160	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BWZ32_RS15165	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BWZ32_RS15170	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BWZ32_RS15175	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BWZ32_RS15180	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
BWZ32_RS15185	COG1534	Rna-binding protein
BWZ32_RS15205	COG2027	D-alanyl-D-alanine carboxypeptidase
BWZ32_RS15210	COG2832	Protein of unknown function (DUF454)
BWZ32_RS15215	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BWZ32_RS15220	COG0739	heme binding
BWZ32_RS15245	COG0628	permease
BWZ32_RS15250	COG2813	Specifically methylates the guanine in position
BWZ32_RS15255	COG0784	Response regulator, receiver
BWZ32_RS15255	COG2205	protein histidine kinase activity
BWZ32_RS15265	COG0601	transmembrane transport
BWZ32_RS15270	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BWZ32_RS15275	COG0444	Belongs to the ABC transporter superfamily
BWZ32_RS15280	COG4608	Belongs to the ABC transporter superfamily
BWZ32_RS15290	COG2971	BadF BadG BcrA BcrD
BWZ32_RS15305	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BWZ32_RS15320	COG1840	ABC-type Fe3 transport system, periplasmic component
BWZ32_RS15325	COG0004	ammonium transporteR
BWZ32_RS15330	COG0347	Belongs to the P(II) protein family
BWZ32_RS15335	COG3112	Uncharacterised protein family (UPF0231)
BWZ32_RS15340	COG3835	regulator
BWZ32_RS15345	COG2610	gluconate transmembrane transporter activity
BWZ32_RS15350	COG1929	Belongs to the glycerate kinase type-1 family
BWZ32_RS15355	COG1049	propionate catabolic process, 2-methylcitrate cycle
BWZ32_RS15360	COG1752	Esterase of the alpha-beta hydrolase superfamily
BWZ32_RS15365	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BWZ32_RS15370	COG1643	Atp-dependent helicase
BWZ32_RS15375	COG1489	DNA binding
BWZ32_RS15380	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BWZ32_RS15385	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BWZ32_RS15395	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BWZ32_RS15400	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BWZ32_RS15410	COG0842	Transport permease protein
BWZ32_RS15415	COG1131	(ABC) transporter
BWZ32_RS15420	COG0659	secondary active sulfate transmembrane transporter activity
BWZ32_RS15425	COG0288	reversible hydration of carbon dioxide
BWZ32_RS15440	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BWZ32_RS15445	COG0508	dehydrogenase complex catalyzes the overall conversion of
BWZ32_RS15450	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
BWZ32_RS15455	COG2186	Transcriptional regulator
BWZ32_RS15460	COG3023	N-Acetylmuramoyl-L-alanine amidase
BWZ32_RS15475	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BWZ32_RS15480	COG1459	type II secretion system
BWZ32_RS15500	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
BWZ32_RS15505	COG0335	large ribosomal subunit rRNA binding
BWZ32_RS15510	COG0336	Belongs to the RNA methyltransferase TrmD family
BWZ32_RS15515	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BWZ32_RS15520	COG0228	four-way junction DNA binding
BWZ32_RS15525	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BWZ32_RS15530	COG4137	Cytochrome C assembly protein
BWZ32_RS15535	COG4536	flavin adenine dinucleotide binding
BWZ32_RS15540	COG1854	S-ribosylhomocysteine lyase activity
BWZ32_RS15555	COG0612	Peptidase, M16
BWZ32_RS15560	COG1238	metal cluster binding
BWZ32_RS15570	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
BWZ32_RS15575	COG5016	pyruvate
BWZ32_RS15575	COG0511	ligase activity, forming carbon-carbon bonds
BWZ32_RS15580	COG3630	sodium ion export across plasma membrane
BWZ32_RS15625	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BWZ32_RS15630	COG0527	aspartate kinase activity
BWZ32_RS15645	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BWZ32_RS15660	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BWZ32_RS15665	COG4942	peptidase
BWZ32_RS15665	COG1388	LysM domain
BWZ32_RS15670	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BWZ32_RS15685	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BWZ32_RS15695	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BWZ32_RS15705	COG0504	CTP synthase activity
BWZ32_RS15710	COG3956	TIGRFAM MazG family protein
BWZ32_RS15715	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BWZ32_RS15725	COG3437	response regulator, receiver
BWZ32_RS15725	COG3850	Histidine kinase
BWZ32_RS15725	COG4999	Histidine kinase
BWZ32_RS15725	COG2205	protein histidine kinase activity
BWZ32_RS15750	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BWZ32_RS15755	COG1381	Involved in DNA repair and RecF pathway recombination
BWZ32_RS15760	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BWZ32_RS15765	COG0571	ribonuclease III activity
BWZ32_RS15775	COG0481	GTPase activity
BWZ32_RS15780	COG3086	response to oxidative stress
BWZ32_RS15795	COG1595	DNA-templated transcription, initiation
BWZ32_RS15800	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BWZ32_RS15815	COG0354	folic acid binding
BWZ32_RS15830	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BWZ32_RS15835	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BWZ32_RS15840	COG3079	Belongs to the UPF0149 family
BWZ32_RS15845	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
BWZ32_RS15855	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BWZ32_RS15865	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BWZ32_RS15880	COG1279	arginine transmembrane transporter activity
BWZ32_RS15885	COG0668	transmembrane transport
BWZ32_RS15890	COG0191	fructose-bisphosphate aldolase activity
BWZ32_RS15895	COG0126	phosphoglycerate kinase activity
BWZ32_RS15915	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BWZ32_RS15930	COG2356	endonuclease I
BWZ32_RS15940	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BWZ32_RS15950	COG1678	Uncharacterized ACR, COG1678
BWZ32_RS15955	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BWZ32_RS15970	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BWZ32_RS15975	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BWZ32_RS15980	COG0762	integral membrane protein
BWZ32_RS15995	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BWZ32_RS16000	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BWZ32_RS16010	COG2066	Belongs to the glutaminase family
BWZ32_RS16015	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BWZ32_RS16025	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
BWZ32_RS16140	COG3437	response regulator, receiver
BWZ32_RS16160	COG1486	melibiose metabolic process
BWZ32_RS16165	COG1447	Phosphotransferase system cellobiose-specific component IIA
BWZ32_RS16175	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BWZ32_RS16180	COG0726	polysaccharide deacetylase
BWZ32_RS16210	COG0583	DNA-binding transcription factor activity
BWZ32_RS16225	COG0795	lipopolysaccharide-transporting ATPase activity
BWZ32_RS16230	COG0795	lipopolysaccharide-transporting ATPase activity
BWZ32_RS16235	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BWZ32_RS16240	COG2927	DNA polymerase III (CHI subunit)
BWZ32_RS16245	COG0525	valine-tRNA ligase activity
BWZ32_RS16255	COG4269	membrane
BWZ32_RS16265	COG0456	acetyltransferase
BWZ32_RS16300	COG0251	oxidation-reduction process
BWZ32_RS16305	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BWZ32_RS16320	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BWZ32_RS16325	COG0312	modulator of DNA gyrase
BWZ32_RS16330	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BWZ32_RS16335	COG3164	Protein of unknown function
BWZ32_RS16345	COG0424	maF-like protein
BWZ32_RS16350	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BWZ32_RS16355	COG1792	Involved in formation and maintenance of cell shape
BWZ32_RS16360	COG1077	Cell shape determining protein MreB Mrl
BWZ32_RS16390	COG2165	general secretion pathway protein
BWZ32_RS16395	COG2165	general secretion pathway protein
BWZ32_RS16405	COG1459	type II secretion system
BWZ32_RS16410	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BWZ32_RS16420	COG3267	Type II secretory pathway component ExeA
BWZ32_RS16420	COG3409	Peptidoglycan-binding domain 1 protein
BWZ32_RS16445	COG2199	diguanylate cyclase activity
BWZ32_RS16445	COG2200	EAL domain
BWZ32_RS16475	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BWZ32_RS16485	COG0527	aspartate kinase activity
BWZ32_RS16570	COG2201	protein-glutamate methylesterase activity
BWZ32_RS16575	COG0840	transmembrane signaling receptor activity
BWZ32_RS16600	COG1196	nuclear chromosome segregation
BWZ32_RS16615	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BWZ32_RS16630	COG0406	alpha-ribazole phosphatase activity
BWZ32_RS16635	COG2199	diguanylate cyclase activity
BWZ32_RS16635	COG2203	Gaf domain
BWZ32_RS16635	COG2200	EAL domain
BWZ32_RS16645	COG1263	PTS System
BWZ32_RS16645	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BWZ32_RS16650	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BWZ32_RS16660	COG1737	Transcriptional regulator
BWZ32_RS16665	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BWZ32_RS16665	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BWZ32_RS16680	COG0110	maltose O-acetyltransferase activity
BWZ32_RS16685	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BWZ32_RS16690	COG0459	protein refolding
BWZ32_RS16725	COG2204	response regulator
BWZ32_RS16735	COG0259	pyridoxamine-phosphate oxidase activity
BWZ32_RS16765	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BWZ32_RS16785	COG5492	domain, Protein
BWZ32_RS16790	COG3119	arylsulfatase activity
BWZ32_RS16795	COG3119	arylsulfatase activity
BWZ32_RS16800	COG0641	radical SAM
BWZ32_RS16805	COG3119	arylsulfatase activity
BWZ32_RS16815	COG0747	negative chemotaxis
BWZ32_RS16825	COG0601	transmembrane transport
BWZ32_RS16830	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BWZ32_RS16855	COG0659	secondary active sulfate transmembrane transporter activity
BWZ32_RS16860	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BWZ32_RS16870	COG1028	Short-chain dehydrogenase reductase Sdr
BWZ32_RS16880	COG5426	von Willebrand factor, type A
BWZ32_RS16890	COG1132	(ABC) transporter
BWZ32_RS16905	COG3623	hexulose-6-phosphate isomerase
BWZ32_RS16910	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
BWZ32_RS16915	COG0561	phosphatase activity
BWZ32_RS16945	COG1902	pentaerythritol trinitrate reductase activity
BWZ32_RS16950	COG2999	glutathione oxidoreductase activity
BWZ32_RS16955	COG1028	Short-chain dehydrogenase reductase Sdr
BWZ32_RS16970	COG0800	Aldolase
BWZ32_RS16975	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BWZ32_RS16980	COG1904	glucuronate isomerase
BWZ32_RS16985	COG0246	Mannitol dehydrogenase
BWZ32_RS16995	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BWZ32_RS17005	COG2186	Transcriptional regulator
BWZ32_RS17015	COG0513	Belongs to the DEAD box helicase family
BWZ32_RS17020	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BWZ32_RS17025	COG1757	Na H antiporter
BWZ32_RS17050	COG2258	MOSC domain
BWZ32_RS17070	COG1486	melibiose metabolic process
BWZ32_RS17075	COG0583	DNA-binding transcription factor activity
BWZ32_RS17095	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BWZ32_RS17110	COG0840	transmembrane signaling receptor activity
BWZ32_RS17130	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BWZ32_RS17135	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BWZ32_RS17160	COG2015	COG2015, Alkyl sulfatase and related hydrolases
BWZ32_RS17180	COG2207	Transcriptional regulator
BWZ32_RS17185	COG0697	spore germination
BWZ32_RS17190	COG1349	DNA-binding transcription factor activity
BWZ32_RS17200	COG1349	DNA-binding transcription factor activity
BWZ32_RS17210	COG2222	sugar isomerase
BWZ32_RS17215	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BWZ32_RS17225	COG3716	PTS system mannose fructose sorbose family IID component
BWZ32_RS17230	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BWZ32_RS17245	COG0488	(ABC) transporter
BWZ32_RS17265	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BWZ32_RS17270	COG1120	ATPase activity
BWZ32_RS17295	COG0577	efflux transmembrane transporter activity
BWZ32_RS17300	COG1136	(ABC) transporter
BWZ32_RS17300	COG0577	efflux transmembrane transporter activity
BWZ32_RS17305	COG0577	efflux transmembrane transporter activity
BWZ32_RS17305	COG1136	(ABC) transporter
BWZ32_RS17310	COG2176	DNA-directed DNA polymerase activity
BWZ32_RS17325	COG3706	GGDEF domain
BWZ32_RS17360	COG2205	protein histidine kinase activity
BWZ32_RS17375	COG2015	COG2015, Alkyl sulfatase and related hydrolases
BWZ32_RS17405	COG0579	oxidoreductase
BWZ32_RS17415	COG3437	response regulator, receiver
BWZ32_RS17435	COG1357	PFAM Pentapeptide repeats (8 copies)
BWZ32_RS17445	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BWZ32_RS17480	COG0513	Belongs to the DEAD box helicase family
BWZ32_RS17505	COG0583	DNA-binding transcription factor activity
BWZ32_RS17515	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BWZ32_RS17545	COG2814	Major facilitator Superfamily
BWZ32_RS17565	COG1858	cytochrome C peroxidase
BWZ32_RS17590	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BWZ32_RS17600	COG0454	-acetyltransferase
BWZ32_RS17620	COG2205	protein histidine kinase activity
BWZ32_RS17645	COG3046	protein related to deoxyribodipyrimidine photolyase
BWZ32_RS17650	COG2207	Transcriptional regulator
BWZ32_RS17655	COG1881	PFAM PEBP family protein
BWZ32_RS17660	COG0494	nUDIX hydrolase
BWZ32_RS17700	COG0668	transmembrane transport
BWZ32_RS17720	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BWZ32_RS17720	COG3153	acetyltransferase
BWZ32_RS17750	COG1028	Short-chain dehydrogenase reductase Sdr
BWZ32_RS17760	COG1917	Cupin 2, conserved barrel domain protein
BWZ32_RS17790	COG0697	spore germination
BWZ32_RS17795	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BWZ32_RS17800	COG0800	Aldolase
BWZ32_RS17830	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BWZ32_RS17835	COG0823	Involved in the tonB-independent uptake of proteins
BWZ32_RS17840	COG0366	Alpha amylase catalytic
BWZ32_RS17850	COG3366	ferrous iron transmembrane transporter activity
BWZ32_RS17855	COG0700	Nucleoside recognition
BWZ32_RS17860	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BWZ32_RS17875	COG0583	DNA-binding transcription factor activity
BWZ32_RS17895	COG0640	Transcriptional regulator
BWZ32_RS17900	COG0798	PFAM Bile acid sodium symporter
BWZ32_RS17920	COG2194	sulfuric ester hydrolase activity
BWZ32_RS17940	COG1566	PFAM secretion protein HlyD family protein
BWZ32_RS17950	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BWZ32_RS17955	COG2203	Gaf domain
BWZ32_RS17955	COG3706	GGDEF domain
BWZ32_RS17955	COG5001	Diguanylate cyclase
BWZ32_RS17955	COG4251	negative regulation of phosphorylation
BWZ32_RS17960	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BWZ32_RS17975	COG0583	DNA-binding transcription factor activity
BWZ32_RS17985	COG0583	DNA-binding transcription factor activity
BWZ32_RS18000	COG2015	COG2015, Alkyl sulfatase and related hydrolases
BWZ32_RS18025	COG0673	inositol 2-dehydrogenase activity
BWZ32_RS18030	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BWZ32_RS18035	COG2197	response regulator
BWZ32_RS18040	COG0384	phenazine biosynthesis protein PhzF
BWZ32_RS18050	COG0625	glutathione transferase activity
BWZ32_RS18055	COG1879	ABC-type sugar transport system periplasmic component
BWZ32_RS18065	COG3284	Transcriptional regulator
BWZ32_RS18070	COG1012	belongs to the aldehyde dehydrogenase family
BWZ32_RS18080	COG1253	flavin adenine dinucleotide binding
BWZ32_RS18105	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BWZ32_RS18110	COG1609	Transcriptional regulator
BWZ32_RS18125	COG0488	(ABC) transporter
BWZ32_RS18130	COG0814	amino acid
BWZ32_RS18135	COG3033	Beta-eliminating lyase
BWZ32_RS18150	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BWZ32_RS18175	COG0189	ligase activity
BWZ32_RS18175	COG4067	protein conserved in archaea
BWZ32_RS18180	COG0189	ligase activity
BWZ32_RS18195	COG1629	transport
BWZ32_RS18195	COG4774	siderophore transport
BWZ32_RS18200	COG4607	ABC-type enterochelin transport system periplasmic component
BWZ32_RS18210	COG1021	2,3-dihydroxybenzoate-AMP ligase
BWZ32_RS18230	COG1021	2,3-dihydroxybenzoate-AMP ligase
BWZ32_RS18235	COG1169	isochorismate synthase
BWZ32_RS18240	COG1028	Short-chain dehydrogenase reductase Sdr
BWZ32_RS18245	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BWZ32_RS18275	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BWZ32_RS18280	COG0840	transmembrane signaling receptor activity
BWZ32_RS18290	COG2755	lipolytic protein G-D-S-L family
BWZ32_RS18295	COG5001	Diguanylate cyclase
BWZ32_RS18295	COG5002	protein histidine kinase activity
BWZ32_RS18310	COG4160	amino acid transport
BWZ32_RS18315	COG4215	(ABC) transporter
BWZ32_RS18320	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BWZ32_RS18325	COG1126	abc transporter atp-binding protein
BWZ32_RS18330	COG3015	lipoprotein NlpE involved in copper resistance
BWZ32_RS18345	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BWZ32_RS18385	COG2814	Major facilitator Superfamily
BWZ32_RS18410	COG1139	Iron-sulfur cluster binding protein
BWZ32_RS18420	COG1620	l-lactate permease
BWZ32_RS18425	COG0583	DNA-binding transcription factor activity
BWZ32_RS18430	COG1505	serine-type exopeptidase activity
BWZ32_RS18435	COG4172	Belongs to the ABC transporter superfamily
BWZ32_RS18445	COG1067	ATP-dependent peptidase activity
BWZ32_RS18450	COG0402	S-adenosylhomocysteine deaminase activity
BWZ32_RS18455	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BWZ32_RS18465	COG2239	Acts as a magnesium transporter
BWZ32_RS18490	COG0745	RESPONSE REGULATOR receiver
BWZ32_RS18495	COG2205	protein histidine kinase activity
BWZ32_RS18510	COG0121	glutamine amidotransferase
BWZ32_RS18515	COG0531	amino acid
BWZ32_RS18525	COG1522	sequence-specific DNA binding
BWZ32_RS18545	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BWZ32_RS18550	COG0583	DNA-binding transcription factor activity
BWZ32_RS18575	COG2205	protein histidine kinase activity
BWZ32_RS18575	COG0784	Response regulator, receiver
BWZ32_RS18575	COG5002	protein histidine kinase activity
BWZ32_RS18580	COG0534	Mate efflux family protein
BWZ32_RS18585	COG2926	Belongs to the UPF0265 family
BWZ32_RS18600	COG2827	Endonuclease containing a URI domain
BWZ32_RS18610	COG1879	ABC-type sugar transport system periplasmic component
BWZ32_RS18660	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BWZ32_RS18665	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BWZ32_RS18675	COG0183	Belongs to the thiolase family
BWZ32_RS18695	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BWZ32_RS18700	COG1940	carbohydrate kinase activity
BWZ32_RS18705	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
BWZ32_RS18710	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BWZ32_RS18715	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BWZ32_RS18720	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BWZ32_RS18725	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BWZ32_RS18730	COG1737	Transcriptional regulator
BWZ32_RS18735	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
BWZ32_RS18740	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
BWZ32_RS18750	COG3005	denitrification pathway
BWZ32_RS18760	COG0243	molybdopterin cofactor binding
BWZ32_RS18770	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BWZ32_RS18775	COG3850	Histidine kinase
BWZ32_RS18780	COG2197	response regulator
BWZ32_RS18800	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BWZ32_RS18800	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BWZ32_RS18810	COG0516	GMP reductase activity
BWZ32_RS18830	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BWZ32_RS18845	COG3568	Endonuclease Exonuclease Phosphatase
BWZ32_RS18870	COG0513	Belongs to the DEAD box helicase family
BWZ32_RS18880	COG2514	catechol 2,3-dioxygenase activity
BWZ32_RS18885	COG1846	Transcriptional regulator
BWZ32_RS18910	COG0842	Transport permease protein
BWZ32_RS18915	COG1131	(ABC) transporter
BWZ32_RS18925	COG1737	Transcriptional regulator
BWZ32_RS18925	COG0837	glucose binding
BWZ32_RS18935	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
BWZ32_RS18945	COG4145	pantothenate transmembrane transporter activity
BWZ32_RS18960	COG0251	oxidation-reduction process
BWZ32_RS18965	COG4251	negative regulation of phosphorylation
BWZ32_RS18965	COG2203	Gaf domain
BWZ32_RS18965	COG3706	GGDEF domain
BWZ32_RS18965	COG5001	Diguanylate cyclase
BWZ32_RS18970	COG0583	DNA-binding transcription factor activity
BWZ32_RS18975	COG2814	Major facilitator Superfamily
BWZ32_RS18990	COG0697	spore germination
BWZ32_RS19005	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BWZ32_RS19015	COG1764	response to oxidative stress
BWZ32_RS19020	COG1846	Transcriptional regulator
BWZ32_RS19045	COG1280	lysine exporter protein (LysE YggA)
BWZ32_RS19055	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BWZ32_RS19060	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BWZ32_RS19065	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BWZ32_RS19070	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
BWZ32_RS19095	COG1612	heme a metabolic process
BWZ32_RS19105	COG2885	chlorophyll binding
BWZ32_RS19110	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BWZ32_RS19115	COG0840	transmembrane signaling receptor activity
BWZ32_RS19130	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BWZ32_RS19135	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BWZ32_RS19155	COG2897	thiosulfate sulfurtransferase activity
BWZ32_RS19165	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BWZ32_RS19170	COG0303	'Molybdopterin
BWZ32_RS19175	COG0302	gtp cyclohydrolase
BWZ32_RS19180	COG1914	H( )-stimulated, divalent metal cation uptake system
BWZ32_RS19190	COG0038	chloride channel
BWZ32_RS19215	COG4989	oxidoreductase activity
BWZ32_RS19225	COG2195	Cleaves the N-terminal amino acid of tripeptides
BWZ32_RS19250	COG0840	transmembrane signaling receptor activity
BWZ32_RS19255	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BWZ32_RS19260	COG0545	Peptidyl-prolyl cis-trans isomerase
BWZ32_RS19290	COG1278	Cold shock
BWZ32_RS19295	COG3036	rescue of stalled ribosome
BWZ32_RS19305	COG2203	Gaf domain
BWZ32_RS19305	COG2199	diguanylate cyclase activity
BWZ32_RS19315	COG1482	cell wall glycoprotein biosynthetic process
BWZ32_RS19320	COG2271	Major facilitator Superfamily
BWZ32_RS19325	COG3851	Histidine kinase
BWZ32_RS19330	COG2197	response regulator
BWZ32_RS19350	COG2130	NADP-dependent
BWZ32_RS19355	COG1309	transcriptional regulator
BWZ32_RS19370	COG1278	Cold shock
BWZ32_RS19395	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BWZ32_RS19400	COG1960	acyl-CoA dehydrogenase activity
BWZ32_RS19420	COG1960	acyl-CoA dehydrogenase activity
BWZ32_RS19425	COG1024	Enoyl-CoA hydratase
BWZ32_RS19430	COG1024	Enoyl-CoA hydratase
BWZ32_RS19440	COG1028	Short-chain dehydrogenase reductase Sdr
BWZ32_RS19480	COG2994	toxin metabolic process
BWZ32_RS19485	COG3064	Membrane
BWZ32_RS19485	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
BWZ32_RS19485	COG1073	alpha beta
BWZ32_RS19545	COG3437	response regulator, receiver
BWZ32_RS19545	COG0784	Response regulator, receiver
BWZ32_RS19550	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BWZ32_RS19550	COG4191	Histidine kinase
BWZ32_RS19560	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
BWZ32_RS19585	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BWZ32_RS19590	COG3186	Phenylalanine-4-hydroxylase
BWZ32_RS19595	COG2154	pterin-4-alpha-carbinolamine dehydratase
BWZ32_RS19615	COG3530	Putative quorum-sensing-regulated virulence factor
BWZ32_RS19635	COG0515	serine threonine protein kinase
BWZ32_RS19635	COG2815	serine threonine protein kinase
BWZ32_RS19670	COG0631	protein serine/threonine phosphatase activity
BWZ32_RS19795	COG1704	LemA family
BWZ32_RS19800	COG3069	C4-dicarboxylate transmembrane transporter activity
BWZ32_RS19810	COG0312	modulator of DNA gyrase
BWZ32_RS19815	COG0312	modulator of DNA gyrase
BWZ32_RS19820	COG0584	glycerophosphoryl diester phosphodiesterase
BWZ32_RS19840	COG0840	transmembrane signaling receptor activity
BWZ32_RS19845	COG0840	transmembrane signaling receptor activity
BWZ32_RS19850	COG0366	Alpha amylase catalytic
BWZ32_RS19855	COG0456	acetyltransferase
BWZ32_RS19855	COG1214	PFAM Peptidase M22, glycoprotease
BWZ32_RS19860	COG0243	molybdopterin cofactor binding
BWZ32_RS19865	COG1648	precorrin-2 dehydrogenase activity
BWZ32_RS19865	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BWZ32_RS19880	COG3707	response regulator
BWZ32_RS19885	COG1116	anion transmembrane transporter activity
BWZ32_RS19885	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BWZ32_RS19890	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BWZ32_RS19895	COG1116	anion transmembrane transporter activity
BWZ32_RS19900	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BWZ32_RS19900	COG2146	nitrite reductase [NAD(P)H] activity
BWZ32_RS19915	COG2199	diguanylate cyclase activity
BWZ32_RS19925	COG0523	cobalamin synthesis protein
BWZ32_RS19935	COG0513	Belongs to the DEAD box helicase family
BWZ32_RS19940	COG0010	Belongs to the arginase family
BWZ32_RS19950	COG3706	GGDEF domain
BWZ32_RS19950	COG2203	Gaf domain
BWZ32_RS19950	COG4251	negative regulation of phosphorylation
BWZ32_RS19950	COG5001	Diguanylate cyclase
BWZ32_RS19960	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BWZ32_RS19995	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BWZ32_RS20030	COG0811	peptide transport
BWZ32_RS20035	COG0811	peptide transport
BWZ32_RS20040	COG0848	biopolymer transport protein
BWZ32_RS20055	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BWZ32_RS20075	COG0534	Mate efflux family protein
BWZ32_RS20085	COG0477	Major facilitator Superfamily
BWZ32_RS20090	COG3118	belongs to the thioredoxin family
BWZ32_RS20095	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BWZ32_RS20150	COG1328	CTP reductase activity
BWZ32_RS20155	COG0602	queuosine metabolic process
BWZ32_RS20160	COG0840	transmembrane signaling receptor activity
BWZ32_RS20170	COG0189	ligase activity
BWZ32_RS20170	COG4067	protein conserved in archaea
BWZ32_RS20190	COG0725	ABC transporter, periplasmic molybdate-binding protein
BWZ32_RS20195	COG4149	molybdate abc transporter
BWZ32_RS20205	COG0697	spore germination
BWZ32_RS20210	COG1846	Transcriptional regulator
BWZ32_RS20220	COG2199	diguanylate cyclase activity
BWZ32_RS20245	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
BWZ32_RS20250	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
BWZ32_RS20260	COG0745	RESPONSE REGULATOR receiver
BWZ32_RS20275	COG3140	Belongs to the UPF0181 family
BWZ32_RS20285	COG0023	Translation Initiation Factor
BWZ32_RS20295	COG1181	Belongs to the D-alanine--D-alanine ligase family
BWZ32_RS20305	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BWZ32_RS20305	COG0045	succinate-CoA ligase (ADP-forming) activity
BWZ32_RS20305	COG1042	CoA-binding domain protein
BWZ32_RS20310	COG0583	DNA-binding transcription factor activity
BWZ32_RS20320	COG5001	Diguanylate cyclase
BWZ32_RS20320	COG5002	protein histidine kinase activity
BWZ32_RS20320	COG3447	MASE1 domain protein
BWZ32_RS20330	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BWZ32_RS20335	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BWZ32_RS20340	COG1984	allophanate hydrolase subunit 2
BWZ32_RS20345	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BWZ32_RS20345	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
BWZ32_RS20350	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
BWZ32_RS20355	COG4181	ATPase activity
BWZ32_RS20365	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BWZ32_RS20370	COG1716	ATPase activity
BWZ32_RS20370	COG5001	Diguanylate cyclase
BWZ32_RS20385	COG0484	heat shock protein binding
BWZ32_RS20405	COG0583	DNA-binding transcription factor activity
BWZ32_RS20410	COG0366	Alpha amylase catalytic
BWZ32_RS20420	COG4533	DNA binding
BWZ32_RS20430	COG2050	protein possibly involved in aromatic compounds catabolism
BWZ32_RS20445	COG2067	long-chain fatty acid transport protein
BWZ32_RS20450	COG2267	carboxylic ester hydrolase activity
BWZ32_RS20485	COG0737	Belongs to the 5'-nucleotidase family
BWZ32_RS20490	COG3593	DNA synthesis involved in DNA repair
BWZ32_RS20500	COG0583	DNA-binding transcription factor activity
BWZ32_RS20505	COG2116	formate transmembrane transporter activity
BWZ32_RS20510	COG2353	YceI-like domain
BWZ32_RS20515	COG3038	cytochrome b561
BWZ32_RS20530	COG0513	Belongs to the DEAD box helicase family
BWZ32_RS20550	COG0546	phosphoglycolate phosphatase activity
BWZ32_RS20555	COG0784	Response regulator, receiver
BWZ32_RS20555	COG3437	response regulator, receiver
BWZ32_RS20570	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BWZ32_RS20575	COG2759	Belongs to the formate--tetrahydrofolate ligase family
BWZ32_RS20580	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BWZ32_RS20590	COG2207	Transcriptional regulator
BWZ32_RS20595	COG1979	alcohol dehydrogenase
BWZ32_RS20605	COG4191	Histidine kinase
BWZ32_RS20615	COG2271	Major facilitator Superfamily
BWZ32_RS20620	COG0469	pyruvate kinase activity
BWZ32_RS20645	COG1609	Transcriptional regulator
BWZ32_RS20650	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BWZ32_RS20650	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BWZ32_RS20655	COG1105	Belongs to the carbohydrate kinase PfkB family
BWZ32_RS20660	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
BWZ32_RS20660	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BWZ32_RS20660	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BWZ32_RS20710	COG0509	glycine decarboxylation via glycine cleavage system
BWZ32_RS20715	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BWZ32_RS20715	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BWZ32_RS20730	COG1132	(ABC) transporter
BWZ32_RS20740	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BWZ32_RS20770	COG2814	Major facilitator Superfamily
BWZ32_RS20800	COG0641	radical SAM
BWZ32_RS20810	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
BWZ32_RS20845	COG0714	Associated with various cellular activities
BWZ32_RS20850	COG0641	radical SAM
BWZ32_RS20855	COG3119	arylsulfatase activity
BWZ32_RS20865	COG3119	arylsulfatase activity
BWZ32_RS20870	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BWZ32_RS20875	COG0513	Belongs to the DEAD box helicase family
BWZ32_RS20880	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
BWZ32_RS20895	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BWZ32_RS20920	COG1716	ATPase activity
BWZ32_RS20920	COG5001	Diguanylate cyclase
BWZ32_RS20930	COG0513	Belongs to the DEAD box helicase family
BWZ32_RS20955	COG3005	denitrification pathway
BWZ32_RS20960	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BWZ32_RS20985	COG1879	ABC-type sugar transport system periplasmic component
BWZ32_RS20990	COG1803	Methylglyoxal synthase
BWZ32_RS20995	COG0210	DNA helicase
BWZ32_RS21000	COG1289	transmembrane transporter activity
BWZ32_RS21030	COG0789	Transcriptional regulator
BWZ32_RS21035	COG4604	ABC transporter, ATP-binding protein
BWZ32_RS21040	COG4605	iron ion homeostasis
BWZ32_RS21045	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BWZ32_RS21065	COG0110	maltose O-acetyltransferase activity
BWZ32_RS21075	COG3290	protein histidine kinase activity
BWZ32_RS21080	COG0471	metal ion transport
BWZ32_RS21170	COG4964	Belongs to the GSP D family
BWZ32_RS21190	COG0583	DNA-binding transcription factor activity
BWZ32_RS21200	COG0419	ATPase involved in DNA repair
BWZ32_RS21205	COG0420	3'-5' exonuclease activity
BWZ32_RS21210	COG3437	response regulator, receiver
BWZ32_RS21225	COG2172	sigma factor antagonist activity
BWZ32_RS21235	COG1366	Belongs to the anti-sigma-factor antagonist family
BWZ32_RS21250	COG0456	acetyltransferase
BWZ32_RS21260	COG0784	Response regulator, receiver
BWZ32_RS21260	COG0835	chemotaxis
BWZ32_RS21270	COG1609	Transcriptional regulator
BWZ32_RS21275	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BWZ32_RS21280	COG1879	ABC-type sugar transport system periplasmic component
BWZ32_RS21285	COG1172	Belongs to the binding-protein-dependent transport system permease family
BWZ32_RS21295	COG1869	D-ribose catabolic process
BWZ32_RS21310	COG2315	Protein conserved in bacteria
BWZ32_RS21315	COG2425	protein containing a von Willebrand factor type A (vWA) domain
BWZ32_RS21330	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
BWZ32_RS21345	COG1288	antiporter activity
BWZ32_RS21355	COG0671	phosphoesterase, PA-phosphatase related
BWZ32_RS21360	COG3097	Belongs to the UPF0267 family
BWZ32_RS21370	COG2962	Rard protein
BWZ32_RS21395	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BWZ32_RS21400	COG0814	amino acid
BWZ32_RS21425	COG3174	membrane
BWZ32_RS21430	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BWZ32_RS21460	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BWZ32_RS21465	COG0443	Heat shock 70 kDa protein
BWZ32_RS21470	COG1454	alcohol dehydrogenase
BWZ32_RS21480	COG2133	pyrroloquinoline quinone binding
BWZ32_RS21485	COG1619	proteins homologs of microcin C7 resistance protein MccF
BWZ32_RS21495	COG0546	phosphoglycolate phosphatase activity
BWZ32_RS21500	COG0247	lactate metabolic process
BWZ32_RS21510	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BWZ32_RS21530	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BWZ32_RS21545	COG3059	membrane
BWZ32_RS21550	COG4175	Glycine betaine
BWZ32_RS21570	COG1012	belongs to the aldehyde dehydrogenase family
BWZ32_RS21575	COG1309	transcriptional regulator
BWZ32_RS21595	COG1686	Belongs to the peptidase S11 family
BWZ32_RS21615	COG1760	l-serine dehydratase
BWZ32_RS21620	COG3104	oligopeptide transport
BWZ32_RS21630	COG0583	DNA-binding transcription factor activity
BWZ32_RS21635	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BWZ32_RS21655	COG3842	ATPase activity
BWZ32_RS21665	COG1840	ABC-type Fe3 transport system, periplasmic component
BWZ32_RS21675	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BWZ32_RS21685	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BWZ32_RS21685	COG2207	Transcriptional regulator
BWZ32_RS21690	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BWZ32_RS21715	COG1011	Hydrolase
BWZ32_RS21740	COG1765	OsmC-like protein
BWZ32_RS21745	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BWZ32_RS21745	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BWZ32_RS21750	COG3706	GGDEF domain
BWZ32_RS21765	COG0840	transmembrane signaling receptor activity
BWZ32_RS21785	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BWZ32_RS21810	COG2084	Dehydrogenase
BWZ32_RS21820	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BWZ32_RS21830	COG0739	heme binding
BWZ32_RS21850	COG3314	Sporulation integral membrane protein YlbJ
BWZ32_RS21865	COG0840	transmembrane signaling receptor activity
BWZ32_RS21875	COG0366	Alpha amylase catalytic
BWZ32_RS21880	COG0589	response to stress
BWZ32_RS21955	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BWZ32_RS21960	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BWZ32_RS21965	COG0784	Response regulator, receiver
BWZ32_RS21965	COG0835	chemotaxis
BWZ32_RS21975	COG0748	coenzyme F420 binding
BWZ32_RS21980	COG3721	Heme iron utilization protein
BWZ32_RS21990	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
BWZ32_RS21995	COG0811	peptide transport
BWZ32_RS22000	COG0848	biopolymer transport protein
BWZ32_RS22010	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BWZ32_RS22060	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BWZ32_RS22065	COG3217	Mosc domain protein beta barrel domain protein
BWZ32_RS22065	COG0633	Ferredoxin
BWZ32_RS22065	COG3217	Mosc domain protein beta barrel domain protein
BWZ32_RS22065	COG0633	Ferredoxin
BWZ32_RS22070	COG0418	dihydroorotase activity
BWZ32_RS22080	COG2354	Protein conserved in bacteria
BWZ32_RS22110	COG3833	ABC-type maltose transport systems, permease component
BWZ32_RS22115	COG1175	transmembrane transport
BWZ32_RS22130	COG3842	ATPase activity
BWZ32_RS22135	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BWZ32_RS22145	COG1596	polysaccharide export
BWZ32_RS22215	COG0714	Associated with various cellular activities
BWZ32_RS22235	COG2304	oxidoreductase activity
BWZ32_RS22245	COG5001	Diguanylate cyclase
BWZ32_RS22245	COG4251	negative regulation of phosphorylation
BWZ32_RS22245	COG2203	Gaf domain
BWZ32_RS22245	COG3706	GGDEF domain
BWZ32_RS22250	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BWZ32_RS22255	COG0581	inorganic phosphate transmembrane transporter activity
BWZ32_RS22260	COG0573	inorganic phosphate transmembrane transporter activity
BWZ32_RS22305	COG0513	Belongs to the DEAD box helicase family
BWZ32_RS22315	COG1376	ErfK ybiS ycfS ynhG family protein
BWZ32_RS22315	COG1388	LysM domain
BWZ32_RS22320	COG0415	Belongs to the DNA photolyase family
BWZ32_RS22325	COG0789	Transcriptional regulator
BWZ32_RS22330	COG3272	Protein of unknown function (DUF1722)
BWZ32_RS22335	COG0813	purine-nucleoside phosphorylase activity
BWZ32_RS22360	COG1566	PFAM secretion protein HlyD family protein
BWZ32_RS22365	COG4720	Psort location CytoplasmicMembrane, score
BWZ32_RS22385	COG0793	Belongs to the peptidase S41A family
BWZ32_RS22385	COG4946	Tricorn protease homolog
BWZ32_RS22390	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BWZ32_RS22415	COG0668	transmembrane transport
BWZ32_RS22435	COG1538	Outer membrane efflux protein
BWZ32_RS22445	COG2274	protein secretion by the type I secretion system
BWZ32_RS22455	COG3111	PFAM Bacterial OB fold (BOF) protein
BWZ32_RS22470	COG2197	response regulator
BWZ32_RS22480	COG2197	response regulator
BWZ32_RS22490	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
BWZ32_RS22525	COG3040	lipid binding
BWZ32_RS22580	COG3240	lipase activity
BWZ32_RS22595	COG2211	Major facilitator Superfamily
BWZ32_RS22605	COG0346	lactoylglutathione lyase activity
BWZ32_RS22625	COG0753	catalase activity
BWZ32_RS22645	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BWZ32_RS22655	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BWZ32_RS22670	COG0393	Putative heavy-metal-binding
BWZ32_RS22690	COG4771	TonB-dependent receptor
BWZ32_RS22695	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BWZ32_RS22700	COG0039	L-malate dehydrogenase activity
BWZ32_RS22720	COG2814	Major facilitator Superfamily
BWZ32_RS22795	COG0351	phosphomethylpyrimidine kinase
BWZ32_RS22800	COG0671	phosphoesterase, PA-phosphatase related
BWZ32_RS22815	COG0561	phosphatase activity
BWZ32_RS22825	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BWZ32_RS22830	COG0076	glutamate decarboxylase activity
BWZ32_RS22835	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BWZ32_RS22860	COG4221	oxidoreductase activity
BWZ32_RS22875	COG0745	RESPONSE REGULATOR receiver
BWZ32_RS22880	COG2205	protein histidine kinase activity
BWZ32_RS22885	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BWZ32_RS22890	COG2194	sulfuric ester hydrolase activity
BWZ32_RS22910	COG2356	endonuclease I
BWZ32_RS22925	COG3706	GGDEF domain
BWZ32_RS22935	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BWZ32_RS22970	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BWZ32_RS23015	COG1301	dicarboxylic acid transport
BWZ32_RS23025	COG0137	argininosuccinate synthase activity
BWZ32_RS23045	COG1733	regulation of RNA biosynthetic process
BWZ32_RS23050	COG0583	DNA-binding transcription factor activity
BWZ32_RS23070	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
BWZ32_RS23105	COG0583	DNA-binding transcription factor activity
BWZ32_RS23110	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BWZ32_RS23115	COG0583	DNA-binding transcription factor activity
BWZ32_RS23125	COG3383	formate dehydrogenase (NAD+) activity
BWZ32_RS23145	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BWZ32_RS23155	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BWZ32_RS23165	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BWZ32_RS23170	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BWZ32_RS23180	COG2207	Transcriptional regulator
BWZ32_RS23185	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BWZ32_RS23185	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BWZ32_RS23185	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BWZ32_RS23190	COG1482	cell wall glycoprotein biosynthetic process
BWZ32_RS23260	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
BWZ32_RS23265	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BWZ32_RS23270	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BWZ32_RS23280	COG2211	Major facilitator Superfamily
BWZ32_RS23295	COG3250	beta-galactosidase activity
BWZ32_RS23305	COG1129	ABC transporter
BWZ32_RS23315	COG1609	Transcriptional regulator
BWZ32_RS23340	COG0564	pseudouridine synthase activity
BWZ32_RS23380	COG1566	PFAM secretion protein HlyD family protein
BWZ32_RS23390	COG0534	Mate efflux family protein
BWZ32_RS23395	COG1472	Belongs to the glycosyl hydrolase 3 family
BWZ32_RS23410	COG4580	involved in the transport of maltose and maltodextrins
BWZ32_RS23425	COG1609	Transcriptional regulator
BWZ32_RS23435	COG4608	Belongs to the ABC transporter superfamily
BWZ32_RS23440	COG0444	Belongs to the ABC transporter superfamily
BWZ32_RS23445	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BWZ32_RS23455	COG0747	negative chemotaxis
BWZ32_RS23465	COG1609	Transcriptional regulator
BWZ32_RS23470	COG3842	ATPase activity
BWZ32_RS23480	COG0395	ABC-type sugar transport system, permease component
BWZ32_RS23495	COG1609	Transcriptional regulator
BWZ32_RS23520	COG2199	diguanylate cyclase activity
BWZ32_RS23550	COG0642	Histidine kinase
BWZ32_RS23560	COG0586	Pfam SNARE associated Golgi protein
BWZ32_RS23565	COG0387	Pfam Sodium calcium exchanger
BWZ32_RS23575	COG0583	DNA-binding transcription factor activity
BWZ32_RS23580	COG0583	DNA-binding transcription factor activity
BWZ32_RS23590	COG0612	Peptidase, M16
BWZ32_RS23595	COG1283	sodium-dependent phosphate transmembrane transporter activity
BWZ32_RS23600	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BWZ32_RS23605	COG0625	glutathione transferase activity
BWZ32_RS23610	COG1012	belongs to the aldehyde dehydrogenase family
BWZ32_RS23665	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BWZ32_RS23670	COG0840	transmembrane signaling receptor activity
BWZ32_RS23675	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BWZ32_RS23680	COG1640	4-alpha-glucanotransferase
BWZ32_RS23685	COG0058	SHG alpha-glucan phosphorylase activity
BWZ32_RS23690	COG2909	trisaccharide binding
BWZ32_RS23705	COG1999	signal sequence binding
BWZ32_RS23710	COG2847	Copper chaperone PCu(A)C
BWZ32_RS23715	COG1162	GTPase activity
BWZ32_RS23720	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
BWZ32_RS23730	COG0531	amino acid
BWZ32_RS23735	COG1982	Orn Lys Arg decarboxylase major
BWZ32_RS23790	COG3706	GGDEF domain
BWZ32_RS23805	COG1741	Belongs to the pirin family
BWZ32_RS23810	COG3123	guanosine phosphorylase activity
BWZ32_RS23830	COG1309	transcriptional regulator
BWZ32_RS23850	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BWZ32_RS23855	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BWZ32_RS23860	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BWZ32_RS23880	COG0189	ligase activity
BWZ32_RS23895	COG0363	glucosamine-6-phosphate deaminase activity
BWZ32_RS23905	COG0786	glutamate:sodium symporter activity
BWZ32_RS23910	COG0786	glutamate:sodium symporter activity
BWZ32_RS23935	COG3275	phosphorelay sensor kinase activity
BWZ32_RS23950	COG4591	ABC-type transport system involved in lipoprotein release permease component
BWZ32_RS23955	COG1136	(ABC) transporter
BWZ32_RS23965	COG0583	DNA-binding transcription factor activity
BWZ32_RS23975	COG0217	transcriptional regulatory protein
BWZ32_RS23995	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BWZ32_RS23995	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
BWZ32_RS24005	COG0444	Belongs to the ABC transporter superfamily
BWZ32_RS24010	COG4608	Belongs to the ABC transporter superfamily
BWZ32_RS24035	COG1444	tRNA N-acetyltransferase activity
BWZ32_RS24045	COG0745	RESPONSE REGULATOR receiver
BWZ32_RS24060	COG0835	chemotaxis