locus-tag	class	description
F6X00_RS00025	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
F6X00_RS00035	COG0583	DNA-binding transcription factor activity
F6X00_RS00040	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
F6X00_RS00045	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
F6X00_RS00050	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
F6X00_RS00080	COG0484	heat shock protein binding
F6X00_RS00085	COG0443	Heat shock 70 kDa protein
F6X00_RS00115	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
F6X00_RS00120	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
F6X00_RS00125	COG0497	DNA recombination
F6X00_RS00130	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
F6X00_RS00135	COG2914	Belongs to the UPF0125 (RnfH) family
F6X00_RS00140	COG2867	negative regulation of translational initiation
F6X00_RS00145	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
F6X00_RS00155	COG0582	viral genome integration into host DNA
F6X00_RS00180	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
F6X00_RS00270	COG0009	L-threonylcarbamoyladenylate synthase
F6X00_RS00290	COG0583	DNA-binding transcription factor activity
F6X00_RS00300	COG1115	amino acid carrier protein
F6X00_RS00305	COG1584	GPR1 FUN34 yaaH family protein
F6X00_RS00315	COG0518	GMP synthase (glutamine-hydrolyzing) activity
F6X00_RS00315	COG0519	Catalyzes the synthesis of GMP from XMP
F6X00_RS00320	COG0517	IMP dehydrogenase activity
F6X00_RS00320	COG0516	GMP reductase activity
F6X00_RS00335	COG2203	Gaf domain
F6X00_RS00335	COG2199	diguanylate cyclase activity
F6X00_RS00345	COG1160	GTP binding
F6X00_RS00350	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
F6X00_RS00355	COG2976	Protein conserved in bacteria
F6X00_RS00360	COG0124	histidyl-tRNA synthetase
F6X00_RS00365	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
F6X00_RS00375	COG0820	rRNA (adenine-C2-)-methyltransferase activity
F6X00_RS00380	COG0105	UTP biosynthetic process
F6X00_RS00385	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
F6X00_RS00390	COG2975	iron-sulfur cluster assembly
F6X00_RS00395	COG0633	Ferredoxin
F6X00_RS00400	COG0443	Heat shock 70 kDa protein
F6X00_RS00410	COG0316	Belongs to the HesB IscA family
F6X00_RS00415	COG0822	iron-sulfur transferase activity
F6X00_RS00425	COG1959	2 iron, 2 sulfur cluster binding
F6X00_RS00430	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
F6X00_RS00435	COG0483	inositol monophosphate 1-phosphatase activity
F6X00_RS00440	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
F6X00_RS00445	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
F6X00_RS00450	COG1862	Preprotein translocase
F6X00_RS00455	COG0343	queuine tRNA-ribosyltransferase activity
F6X00_RS00460	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
F6X00_RS00470	COG0517	IMP dehydrogenase activity
F6X00_RS00480	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
F6X00_RS00485	COG0583	DNA-binding transcription factor activity
F6X00_RS00490	COG0450	alkyl hydroperoxide reductase
F6X00_RS00515	COG0704	Plays a role in the regulation of phosphate uptake
F6X00_RS00520	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
F6X00_RS00525	COG0581	inorganic phosphate transmembrane transporter activity
F6X00_RS00530	COG0573	inorganic phosphate transmembrane transporter activity
F6X00_RS00540	COG0248	Ppx GppA phosphatase
F6X00_RS00550	COG5002	protein histidine kinase activity
F6X00_RS00555	COG0745	RESPONSE REGULATOR receiver
F6X00_RS00570	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
F6X00_RS00610	COG0542	response to heat
F6X00_RS00625	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
F6X00_RS00635	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
F6X00_RS00640	COG1605	Chorismate mutase
F6X00_RS00640	COG0077	Prephenate dehydratase
F6X00_RS00645	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
F6X00_RS00650	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
F6X00_RS00660	COG0488	(ABC) transporter
F6X00_RS00670	COG0739	heme binding
F6X00_RS00675	COG0287	Prephenate dehydrogenase
F6X00_RS00675	COG1605	Chorismate mutase
F6X00_RS00690	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
F6X00_RS00705	COG1966	Carbon starvation protein
F6X00_RS00710	COG3275	phosphorelay sensor kinase activity
F6X00_RS00720	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
F6X00_RS00725	COG1047	Peptidyl-prolyl cis-trans
F6X00_RS00730	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
F6X00_RS00735	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
F6X00_RS00740	COG0196	riboflavin kinase activity
F6X00_RS00745	COG0728	peptidoglycan biosynthetic process
F6X00_RS00750	COG0268	Binds directly to 16S ribosomal RNA
F6X00_RS00755	COG0640	Transcriptional regulator
F6X00_RS00760	COG0583	DNA-binding transcription factor activity
F6X00_RS00765	COG1283	sodium-dependent phosphate transmembrane transporter activity
F6X00_RS00785	COG0730	response to heat
F6X00_RS00795	COG0494	nUDIX hydrolase
F6X00_RS00800	COG3066	DNA modification
F6X00_RS00810	COG0667	Aldo Keto reductase
F6X00_RS00825	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
F6X00_RS00835	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
F6X00_RS00840	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
F6X00_RS00845	COG4974	Belongs to the 'phage' integrase family
F6X00_RS00865	COG0513	Belongs to the DEAD box helicase family
F6X00_RS00875	COG1115	amino acid carrier protein
F6X00_RS00890	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
F6X00_RS00900	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
F6X00_RS00905	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
F6X00_RS00910	COG0083	homoserine kinase activity
F6X00_RS00925	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
F6X00_RS00935	COG0745	RESPONSE REGULATOR receiver
F6X00_RS00945	COG5002	protein histidine kinase activity
F6X00_RS00945	COG0784	Response regulator, receiver
F6X00_RS00945	COG2198	Histidine kinase
F6X00_RS00950	COG3706	GGDEF domain
F6X00_RS00950	COG4251	negative regulation of phosphorylation
F6X00_RS00950	COG2203	Gaf domain
F6X00_RS00950	COG5001	Diguanylate cyclase
F6X00_RS00955	COG1242	4 iron, 4 sulfur cluster binding
F6X00_RS00960	COG0069	glutamate synthase activity
F6X00_RS00960	COG0067	glutamate synthase
F6X00_RS00960	COG0070	glutamate synthase
F6X00_RS00970	COG0067	glutamate synthase
F6X00_RS00970	COG0070	glutamate synthase
F6X00_RS00970	COG0069	glutamate synthase activity
F6X00_RS00975	COG0493	'glutamate synthase
F6X00_RS00985	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
F6X00_RS01000	COG2860	membrane
F6X00_RS01005	COG0583	DNA-binding transcription factor activity
F6X00_RS01010	COG0730	response to heat
F6X00_RS01020	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
F6X00_RS01025	COG0505	Belongs to the CarA family
F6X00_RS01035	COG0494	nUDIX hydrolase
F6X00_RS01040	COG0653	protein targeting
F6X00_RS01050	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
F6X00_RS01055	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
F6X00_RS01060	COG0849	cell division
F6X00_RS01065	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
F6X00_RS01070	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
F6X00_RS01080	COG0772	Belongs to the SEDS family
F6X00_RS01085	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
F6X00_RS01090	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
F6X00_RS01095	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
F6X00_RS01105	COG0768	penicillin binding
F6X00_RS01110	COG3116	cell division
F6X00_RS01115	COG0275	rRNA processing
F6X00_RS01125	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
F6X00_RS01130	COG3107	peptidoglycan biosynthetic process
F6X00_RS01135	COG0792	nuclease activity
F6X00_RS01140	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
F6X00_RS01145	COG2823	Periplasmic or secreted lipoprotein
F6X00_RS01150	COG2969	positive regulation of protein catabolic process
F6X00_RS01155	COG0625	glutathione transferase activity
F6X00_RS01160	COG2857	Cytochrome c1
F6X00_RS01165	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
F6X00_RS01170	COG0723	plastoquinol--plastocyanin reductase activity
F6X00_RS01175	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
F6X00_RS01180	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
F6X00_RS01185	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
F6X00_RS01190	COG3105	Protein conserved in bacteria
F6X00_RS01195	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
F6X00_RS01200	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
F6X00_RS01215	COG3150	esterase
F6X00_RS01225	COG3151	Protein conserved in bacteria
F6X00_RS01230	COG0494	nUDIX hydrolase
F6X00_RS01235	COG1538	Outer membrane efflux protein
F6X00_RS01245	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
F6X00_RS01255	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
F6X00_RS01260	COG3025	triphosphatase activity
F6X00_RS01265	COG1392	Phosphate transport regulator
F6X00_RS01270	COG0306	phosphate transporter
F6X00_RS01275	COG4991	sh3 domain protein
F6X00_RS01280	COG3267	Type II secretory pathway component ExeA
F6X00_RS01280	COG3409	Peptidoglycan-binding domain 1 protein
F6X00_RS01285	COG0617	tRNA 3'-terminal CCA addition
F6X00_RS01290	COG1968	undecaprenyl-diphosphatase activity
F6X00_RS01295	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
F6X00_RS01300	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
F6X00_RS01310	COG0596	Alpha beta hydrolase
F6X00_RS01315	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
F6X00_RS01320	COG0828	Belongs to the bacterial ribosomal protein bS21 family
F6X00_RS01325	COG1610	YqeY-like protein
F6X00_RS01345	COG0582	viral genome integration into host DNA
F6X00_RS01385	COG3339	Conserved Protein
F6X00_RS01400	COG2003	Belongs to the UPF0758 family
F6X00_RS01405	COG3547	Transposase (IS116 IS110 IS902 family)
F6X00_RS01480	COG1181	Belongs to the D-alanine--D-alanine ligase family
F6X00_RS01535	COG3501	Rhs element vgr protein
F6X00_RS01550	COG2207	Transcriptional regulator
F6X00_RS01570	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
F6X00_RS01575	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
F6X00_RS01575	COG2213	PTS system mannitol-specific
F6X00_RS01580	COG0246	Mannitol dehydrogenase
F6X00_RS01585	COG3722	fumarate hydratase activity
F6X00_RS01590	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
F6X00_RS01595	COG1349	DNA-binding transcription factor activity
F6X00_RS01610	COG3706	GGDEF domain
F6X00_RS01615	COG0440	acetolactate synthase activity
F6X00_RS01620	COG0028	Belongs to the TPP enzyme family
F6X00_RS01625	COG1022	Amp-dependent synthetase and ligase
F6X00_RS01650	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
F6X00_RS01655	COG0473	3-isopropylmalate dehydrogenase activity
F6X00_RS01680	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
F6X00_RS01690	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
F6X00_RS01695	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
F6X00_RS01700	COG2967	ApaG domain
F6X00_RS01715	COG3610	response to peptide
F6X00_RS01720	COG2966	Psort location CytoplasmicMembrane, score
F6X00_RS01730	COG0211	Belongs to the bacterial ribosomal protein bL27 family
F6X00_RS01735	COG0261	This protein binds to 23S rRNA in the presence of protein L20
F6X00_RS01740	COG0142	geranyltranstransferase activity
F6X00_RS01745	COG0039	L-malate dehydrogenase activity
F6X00_RS01750	COG1438	arginine binding
F6X00_RS01755	COG2358	TRAP transporter, solute receptor (TAXI family
F6X00_RS01765	COG0589	response to stress
F6X00_RS01770	COG0204	Acyl-transferase
F6X00_RS01775	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
F6X00_RS01780	COG5007	Belongs to the BolA IbaG family
F6X00_RS01790	COG2854	intermembrane phospholipid transfer
F6X00_RS01795	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
F6X00_RS01800	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
F6X00_RS01805	COG1127	ABC transporter
F6X00_RS01815	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
F6X00_RS01815	COG0517	IMP dehydrogenase activity
F6X00_RS01820	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
F6X00_RS01830	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
F6X00_RS01835	COG1137	ATPase activity
F6X00_RS01845	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
F6X00_RS01850	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
F6X00_RS01855	COG1660	Displays ATPase and GTPase activities
F6X00_RS01860	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
F6X00_RS01865	COG2239	Acts as a magnesium transporter
F6X00_RS01870	COG0312	modulator of DNA gyrase
F6X00_RS01875	COG3028	Belongs to the UPF0307 family
F6X00_RS01880	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
F6X00_RS01885	COG1178	ABC-type Fe3 transport system permease component
F6X00_RS01890	COG4143	(ABC) transporter
F6X00_RS01895	COG0163	prenyltransferase activity
F6X00_RS01900	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
F6X00_RS01905	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
F6X00_RS01910	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
F6X00_RS01920	COG2105	PFAM AIG2 family protein
F6X00_RS01925	COG2911	Protein conserved in bacteria
F6X00_RS01930	COG0729	surface antigen
F6X00_RS01945	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
F6X00_RS01960	COG1136	(ABC) transporter
F6X00_RS01960	COG0577	efflux transmembrane transporter activity
F6X00_RS01980	COG0529	Catalyzes the synthesis of activated sulfate
F6X00_RS01985	COG3273	potassium ion transport
F6X00_RS01985	COG0471	metal ion transport
F6X00_RS01995	COG0175	sulfate reduction
F6X00_RS02000	COG1648	precorrin-2 dehydrogenase activity
F6X00_RS02000	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
F6X00_RS02005	COG0737	Belongs to the 5'-nucleotidase family
F6X00_RS02015	COG2153	protein acetylation
F6X00_RS02025	COG3266	domain, Protein
F6X00_RS02025	COG3061	Opacity-associated protein A
F6X00_RS02030	COG0545	Peptidyl-prolyl cis-trans isomerase
F6X00_RS02040	COG0203	ribosomal protein L17
F6X00_RS02045	COG0202	RNA polymerase activity
F6X00_RS02050	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
F6X00_RS02055	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
F6X00_RS02060	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
F6X00_RS02065	COG0257	Belongs to the bacterial ribosomal protein bL36 family
F6X00_RS02070	COG0201	protein transport
F6X00_RS02075	COG0200	Binds to the 23S rRNA
F6X00_RS02080	COG1841	ribosomal large subunit assembly
F6X00_RS02085	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
F6X00_RS02090	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
F6X00_RS02095	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
F6X00_RS02100	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
F6X00_RS02105	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
F6X00_RS02110	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
F6X00_RS02115	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
F6X00_RS02120	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
F6X00_RS02125	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
F6X00_RS02130	COG0255	Belongs to the universal ribosomal protein uL29 family
F6X00_RS02135	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
F6X00_RS02140	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
F6X00_RS02150	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
F6X00_RS02155	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
F6X00_RS02160	COG0089	rRNA binding
F6X00_RS02165	COG0088	Forms part of the polypeptide exit tunnel
F6X00_RS02180	COG3064	Membrane
F6X00_RS02195	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
F6X00_RS02205	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
F6X00_RS02250	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
F6X00_RS02255	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
F6X00_RS02275	COG1596	polysaccharide export
F6X00_RS02305	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
F6X00_RS02320	COG0859	PFAM glycosyl transferase family 9
F6X00_RS02325	COG1519	Transferase
F6X00_RS02335	COG2089	acid synthase
F6X00_RS02345	COG1083	cytidylyl-transferase
F6X00_RS02350	COG0107	imidazoleglycerol-phosphate synthase activity
F6X00_RS02355	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
F6X00_RS02365	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
F6X00_RS02370	COG1086	Polysaccharide biosynthesis protein
F6X00_RS02385	COG3083	sulfuric ester hydrolase activity
F6X00_RS02390	COG3642	lipopolysaccharide core region biosynthetic process
F6X00_RS02395	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
F6X00_RS02400	COG0859	PFAM glycosyl transferase family 9
F6X00_RS02405	COG0463	Glycosyl transferase, family 2
F6X00_RS02410	COG0859	PFAM glycosyl transferase family 9
F6X00_RS02415	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
F6X00_RS02435	COG0267	Belongs to the bacterial ribosomal protein bL33 family
F6X00_RS02440	COG0227	Belongs to the bacterial ribosomal protein bL28 family
F6X00_RS02445	COG2003	Belongs to the UPF0758 family
F6X00_RS02460	COG1309	transcriptional regulator
F6X00_RS02465	COG1560	Kdo2-lipid A biosynthetic process
F6X00_RS02475	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
F6X00_RS02480	COG1561	YicC-like family, N-terminal region
F6X00_RS02505	COG4608	Belongs to the ABC transporter superfamily
F6X00_RS02510	COG0444	Belongs to the ABC transporter superfamily
F6X00_RS02515	COG0747	negative chemotaxis
F6X00_RS02520	COG4239	(ABC) transporter, permease
F6X00_RS02525	COG4174	ABC transporter (Permease)
F6X00_RS02530	COG4206	TonB-dependent receptor
F6X00_RS02540	COG0811	peptide transport
F6X00_RS02545	COG0811	peptide transport
F6X00_RS02550	COG0848	biopolymer transport protein
F6X00_RS02565	COG0194	GDP metabolic process
F6X00_RS02570	COG1758	RNA polymerase activity
F6X00_RS02575	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
F6X00_RS02580	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
F6X00_RS02585	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
F6X00_RS02590	COG2233	PERMEase
F6X00_RS02600	COG0745	RESPONSE REGULATOR receiver
F6X00_RS02605	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
F6X00_RS02610	COG2183	response to ionizing radiation
F6X00_RS02620	COG0596	Alpha beta hydrolase
F6X00_RS02625	COG1040	competence protein
F6X00_RS02630	COG0316	Belongs to the HesB IscA family
F6X00_RS02630	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
F6X00_RS02635	COG0494	nUDIX hydrolase
F6X00_RS02640	COG1218	3'(2'),5'-bisphosphate nucleotidase
F6X00_RS02650	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
F6X00_RS02655	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
F6X00_RS02660	COG3156	type II secretion system protein K
F6X00_RS02665	COG4795	General secretion pathway protein
F6X00_RS02670	COG2165	general secretion pathway protein
F6X00_RS02675	COG2165	general secretion pathway protein
F6X00_RS02680	COG2165	general secretion pathway protein
F6X00_RS02685	COG1459	type II secretion system
F6X00_RS02690	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
F6X00_RS02700	COG3031	protein transport across the cell outer membrane
F6X00_RS02705	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
F6X00_RS02710	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
F6X00_RS02725	COG0456	acetyltransferase
F6X00_RS02730	COG1490	D-aminoacyl-tRNA deacylase activity
F6X00_RS02735	COG1295	ribonuclease BN
F6X00_RS02755	COG0174	glutamine synthetase
F6X00_RS02765	COG3852	Histidine kinase
F6X00_RS02770	COG2204	response regulator
F6X00_RS02775	COG5001	Diguanylate cyclase
F6X00_RS02775	COG3300	MHYT domain
F6X00_RS02790	COG3078	GTPase activator activity
F6X00_RS02810	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
F6X00_RS02810	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
F6X00_RS02820	COG0084	hydrolase, TatD family'
F6X00_RS02825	COG0805	protein transport
F6X00_RS02830	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
F6X00_RS02850	COG2226	methyltransferase
F6X00_RS02855	COG1322	Protein conserved in bacteria
F6X00_RS02965	COG3118	belongs to the thioredoxin family
F6X00_RS02975	COG0248	Ppx GppA phosphatase
F6X00_RS02980	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
F6X00_RS02990	COG0514	ATP-dependent DNA helicase (RecQ)
F6X00_RS02995	COG2962	Rard protein
F6X00_RS03005	COG1280	lysine exporter protein (LysE YggA)
F6X00_RS03010	COG0210	DNA helicase
F6X00_RS03050	COG0006	proline dipeptidase activity
F6X00_RS03050	COG0006	proline dipeptidase activity
F6X00_RS03060	COG2022	thiamine diphosphate biosynthetic process
F6X00_RS03070	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
F6X00_RS03080	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
F6X00_RS03085	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
F6X00_RS03090	COG2132	Multicopper oxidase
F6X00_RS03125	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
F6X00_RS03135	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
F6X00_RS03140	COG0408	coproporphyrinogen oxidase activity
F6X00_RS03145	COG0009	L-threonylcarbamoyladenylate synthase
F6X00_RS03150	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
F6X00_RS03160	COG0551	DNA topoisomerase type I activity
F6X00_RS03165	COG2922	Belongs to the Smg family
F6X00_RS03170	COG0758	DNA mediated transformation
F6X00_RS03180	COG0242	peptide deformylase activity
F6X00_RS03185	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
F6X00_RS03190	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
F6X00_RS03190	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
F6X00_RS03195	COG0569	domain protein
F6X00_RS03200	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
F6X00_RS03205	COG1272	protein, Hemolysin III
F6X00_RS03210	COG4326	sporulation control protein
F6X00_RS03220	COG3084	Protein conserved in bacteria
F6X00_RS03230	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
F6X00_RS03235	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
F6X00_RS03240	COG0204	Acyl-transferase
F6X00_RS03275	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
F6X00_RS03295	COG3978	acetolactate synthase activity
F6X00_RS03300	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
F6X00_RS03305	COG0129	dihydroxy-acid dehydratase activity
F6X00_RS03315	COG0583	DNA-binding transcription factor activity
F6X00_RS03320	COG2814	Major facilitator Superfamily
F6X00_RS03330	COG0765	amino acid transport
F6X00_RS03335	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
F6X00_RS03340	COG0355	proton-transporting ATP synthase activity, rotational mechanism
F6X00_RS03345	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
F6X00_RS03350	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
F6X00_RS03355	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
F6X00_RS03360	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
F6X00_RS03365	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
F6X00_RS03375	COG0356	it plays a direct role in the translocation of protons across the membrane
F6X00_RS03380	COG3312	ion transport
F6X00_RS03385	COG1475	DNA binding
F6X00_RS03390	COG1192	Involved in chromosome partitioning
F6X00_RS03395	COG0357	Ribosomal RNA small subunit methyltransferase G
F6X00_RS03400	COG0445	tRNA wobble uridine modification
F6X00_RS03405	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
F6X00_RS03415	COG0706	membrane insertase activity
F6X00_RS03425	COG0594	ribonuclease P activity
F6X00_RS03430	COG0230	Belongs to the bacterial ribosomal protein bL34 family
F6X00_RS03435	COG1126	abc transporter atp-binding protein
F6X00_RS03455	COG0592	DNA-directed DNA polymerase activity
F6X00_RS03465	COG0187	DNA topoisomerase II activity
F6X00_RS03470	COG0071	Belongs to the small heat shock protein (HSP20) family
F6X00_RS03480	COG3977	Valine--pyruvate aminotransferase
F6X00_RS03490	COG0752	glycyl-tRNA synthetase alpha subunit
F6X00_RS03495	COG2119	membrane
F6X00_RS03505	COG0425	Belongs to the sulfur carrier protein TusA family
F6X00_RS03520	COG0604	alcohol dehydrogenase
F6X00_RS03525	COG0183	Belongs to the thiolase family
F6X00_RS03535	COG1739	Uncharacterized protein family UPF0029
F6X00_RS03540	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
F6X00_RS03590	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
F6X00_RS03595	COG2960	long-chain fatty acid transporting porin activity
F6X00_RS03600	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F6X00_RS03605	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F6X00_RS03610	COG1309	transcriptional regulator
F6X00_RS03650	COG4172	Belongs to the ABC transporter superfamily
F6X00_RS03655	COG4166	transmembrane transport
F6X00_RS03665	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F6X00_RS03700	COG0515	serine threonine protein kinase
F6X00_RS03700	COG2815	serine threonine protein kinase
F6X00_RS03710	COG0745	RESPONSE REGULATOR receiver
F6X00_RS03715	COG1609	Transcriptional regulator
F6X00_RS03720	COG0129	dihydroxy-acid dehydratase activity
F6X00_RS03725	COG3265	gluconokinase activity
F6X00_RS03730	COG2610	gluconate transmembrane transporter activity
F6X00_RS03735	COG0800	Aldolase
F6X00_RS03740	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
F6X00_RS03745	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
F6X00_RS03755	COG1522	sequence-specific DNA binding
F6X00_RS03760	COG5001	Diguanylate cyclase
F6X00_RS03760	COG5002	protein histidine kinase activity
F6X00_RS03765	COG0742	ribosomal rna small subunit methyltransferase
F6X00_RS03785	COG1528	Iron-storage protein
F6X00_RS03795	COG2081	HI0933 family
F6X00_RS03805	COG2959	enzyme of heme biosynthesis
F6X00_RS03815	COG0181	hydroxymethylbilane synthase activity
F6X00_RS03820	COG3072	Adenylate cyclase
F6X00_RS03825	COG1965	Belongs to the frataxin family
F6X00_RS03835	COG0019	diaminopimelate decarboxylase activity
F6X00_RS03840	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
F6X00_RS03850	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
F6X00_RS03855	COG1011	Hydrolase
F6X00_RS03860	COG2199	diguanylate cyclase activity
F6X00_RS03860	COG2200	EAL domain
F6X00_RS03860	COG3287	FIST C domain
F6X00_RS03880	COG0561	phosphatase activity
F6X00_RS03885	COG2267	carboxylic ester hydrolase activity
F6X00_RS03890	COG1280	lysine exporter protein (LysE YggA)
F6X00_RS03895	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
F6X00_RS03900	COG0640	Transcriptional regulator
F6X00_RS03905	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
F6X00_RS03945	COG2095	MarC family integral membrane protein
F6X00_RS03955	COG0742	ribosomal rna small subunit methyltransferase
F6X00_RS03960	COG0552	protein localization to endoplasmic reticulum
F6X00_RS03965	COG2884	Cell division ATP-binding protein ftsE
F6X00_RS03970	COG2177	Part of the ABC transporter FtsEX involved in
F6X00_RS03980	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
F6X00_RS03985	COG0705	Rhomboid family
F6X00_RS03990	COG1580	Controls the rotational direction of flagella during chemotaxis
F6X00_RS04005	COG2937	Belongs to the GPAT DAPAT family
F6X00_RS04010	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
F6X00_RS04020	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
F6X00_RS04065	COG0328	RNA-DNA hybrid ribonuclease activity
F6X00_RS04085	COG0583	DNA-binding transcription factor activity
F6X00_RS04120	COG3626	phosphonate metabolism
F6X00_RS04125	COG3627	carbon phosphorus lyase activity
F6X00_RS04130	COG4107	phosphonate C-P lyase system protein PhnK
F6X00_RS04135	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
F6X00_RS04140	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
F6X00_RS04185	COG2003	Belongs to the UPF0758 family
F6X00_RS04215	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
F6X00_RS04245	COG0789	Transcriptional regulator
F6X00_RS04260	COG1566	PFAM secretion protein HlyD family protein
F6X00_RS04280	COG0784	Response regulator, receiver
F6X00_RS04280	COG2205	protein histidine kinase activity
F6X00_RS04340	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F6X00_RS04355	COG0346	lactoylglutathione lyase activity
F6X00_RS04370	COG0371	Dehydrogenase
F6X00_RS04375	COG4932	domain protein
F6X00_RS04375	COG5492	domain, Protein
F6X00_RS04395	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
F6X00_RS04410	COG4206	TonB-dependent receptor
F6X00_RS04500	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
F6X00_RS04510	COG0812	UDP-N-acetylmuramate dehydrogenase activity
F6X00_RS04520	COG1072	(Pantothenic acid kinase))
F6X00_RS04545	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
F6X00_RS04550	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
F6X00_RS04565	COG0081	regulation of translation
F6X00_RS04570	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
F6X00_RS04575	COG0222	ribosome binding
F6X00_RS04580	COG0085	RNA polymerase activity
F6X00_RS04585	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
F6X00_RS04590	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
F6X00_RS04610	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
F6X00_RS04615	COG1573	uracil-dna glycosylase
F6X00_RS04620	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
F6X00_RS04625	COG3068	Protein conserved in bacteria
F6X00_RS04630	COG1253	flavin adenine dinucleotide binding
F6X00_RS04645	COG0151	Belongs to the GarS family
F6X00_RS04650	COG0138	bifunctional purine biosynthesis protein purh
F6X00_RS04655	COG0789	Transcriptional regulator
F6X00_RS04660	COG0840	transmembrane signaling receptor activity
F6X00_RS04665	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
F6X00_RS04680	COG0439	Biotin carboxylase
F6X00_RS04685	COG0511	ligase activity, forming carbon-carbon bonds
F6X00_RS04690	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
F6X00_RS04695	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
F6X00_RS04710	COG2814	Major facilitator Superfamily
F6X00_RS04715	COG0784	Response regulator, receiver
F6X00_RS04715	COG2198	Histidine kinase
F6X00_RS04715	COG2205	protein histidine kinase activity
F6X00_RS04730	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
F6X00_RS04740	COG2095	MarC family integral membrane protein
F6X00_RS04750	COG4232	protein-disulfide reductase activity
F6X00_RS04755	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
F6X00_RS04760	COG1027	Aspartate ammonia-lyase
F6X00_RS04770	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
F6X00_RS04780	COG2205	protein histidine kinase activity
F6X00_RS04785	COG0745	RESPONSE REGULATOR receiver
F6X00_RS04790	COG3678	ATP-independent chaperone mediated protein folding
F6X00_RS04800	COG0205	6-phosphofructokinase activity
F6X00_RS04805	COG0534	Mate efflux family protein
F6X00_RS04810	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
F6X00_RS04815	COG0459	protein refolding
F6X00_RS04825	COG1285	pathogenesis
F6X00_RS04830	COG1509	lysine 2,3-aminomutase activity
F6X00_RS04835	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
F6X00_RS04850	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
F6X00_RS04855	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
F6X00_RS04860	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
F6X00_RS04865	COG1053	succinate dehydrogenase
F6X00_RS04870	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
F6X00_RS04890	COG4942	peptidase
F6X00_RS04895	COG1045	serine acetyltransferase
F6X00_RS04900	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
F6X00_RS04905	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
F6X00_RS04910	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
F6X00_RS04915	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
F6X00_RS04925	COG0471	metal ion transport
F6X00_RS04930	COG0688	phosphatidylethanolamine metabolic process
F6X00_RS04935	COG1162	GTPase activity
F6X00_RS04940	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
F6X00_RS05005	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
F6X00_RS05010	COG0802	atpase or kinase
F6X00_RS05015	COG0860	N-Acetylmuramoyl-L-alanine amidase
F6X00_RS05030	COG1923	regulation of RNA biosynthetic process
F6X00_RS05035	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
F6X00_RS05040	COG0330	HflC and HflK could
F6X00_RS05045	COG0330	HflC and HflK could
F6X00_RS05050	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
F6X00_RS05055	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
F6X00_RS05060	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
F6X00_RS05070	COG1959	2 iron, 2 sulfur cluster binding
F6X00_RS05075	COG0402	S-adenosylhomocysteine deaminase activity
F6X00_RS05080	COG0557	exoribonuclease II activity
F6X00_RS05085	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
F6X00_RS05115	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
F6X00_RS05125	COG1012	belongs to the aldehyde dehydrogenase family
F6X00_RS05135	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
F6X00_RS05140	COG3954	Phosphoribulokinase
F6X00_RS05145	COG3089	Belongs to the UPF0270 family
F6X00_RS05150	COG0429	hydrolase of the alpha beta-hydrolase fold
F6X00_RS05160	COG0488	(ABC) transporter
F6X00_RS05165	COG2249	NAD(P)H dehydrogenase (quinone) activity
F6X00_RS05180	COG1047	Peptidyl-prolyl cis-trans
F6X00_RS05190	COG2900	Belongs to the SlyX family
F6X00_RS05200	COG0545	Peptidyl-prolyl cis-trans isomerase
F6X00_RS05205	COG2964	Protein conserved in bacteria
F6X00_RS05215	COG2923	Belongs to the DsrF TusC family
F6X00_RS05220	COG2168	tRNA wobble position uridine thiolation
F6X00_RS05225	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
F6X00_RS05230	COG0049	tRNA binding
F6X00_RS05235	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
F6X00_RS05245	COG2906	2 iron, 2 sulfur cluster binding
F6X00_RS05255	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
F6X00_RS05260	COG0149	triose-phosphate isomerase activity
F6X00_RS05285	COG1494	fructose-1,6-bisphosphatase
F6X00_RS05290	COG3074	FtsZ-dependent cytokinesis
F6X00_RS05300	COG1575	Belongs to the MenA family. Type 1 subfamily
F6X00_RS05305	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
F6X00_RS05310	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
F6X00_RS05320	COG1609	Transcriptional regulator
F6X00_RS05325	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
F6X00_RS05330	COG0254	rRNA binding
F6X00_RS05335	COG0281	malic enzyme
F6X00_RS05340	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
F6X00_RS05345	COG0626	cystathionine gamma-synthase activity
F6X00_RS05350	COG0460	homoserine dehydrogenase
F6X00_RS05350	COG0527	aspartate kinase activity
F6X00_RS05355	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
F6X00_RS05365	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
F6X00_RS05370	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
F6X00_RS05385	COG0137	argininosuccinate synthase activity
F6X00_RS05390	COG0165	Argininosuccinate lyase
F6X00_RS05390	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
F6X00_RS05405	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
F6X00_RS05435	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
F6X00_RS05440	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
F6X00_RS05450	COG0338	D12 class N6 adenine-specific DNA methyltransferase
F6X00_RS05455	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
F6X00_RS05460	COG0360	Binds together with S18 to 16S ribosomal RNA
F6X00_RS05465	COG2965	DNA replication, synthesis of RNA primer
F6X00_RS05475	COG0359	binds to the 23S rRNA
F6X00_RS05490	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
F6X00_RS05545	COG0556	nucleotide-excision repair
F6X00_RS05555	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
F6X00_RS05590	COG0735	belongs to the Fur family
F6X00_RS05620	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
F6X00_RS05700	COG1410	methionine synthase
F6X00_RS05700	COG0646	methionine synthase
F6X00_RS05705	COG0527	aspartate kinase activity
F6X00_RS05710	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
F6X00_RS05740	COG2200	EAL domain
F6X00_RS05740	COG2199	diguanylate cyclase activity
F6X00_RS05765	COG3267	Type II secretory pathway component ExeA
F6X00_RS05765	COG3409	Peptidoglycan-binding domain 1 protein
F6X00_RS05775	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
F6X00_RS05780	COG1459	type II secretion system
F6X00_RS05825	COG1077	Cell shape determining protein MreB Mrl
F6X00_RS05830	COG1792	Involved in formation and maintenance of cell shape
F6X00_RS05835	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
F6X00_RS05840	COG0424	maF-like protein
F6X00_RS05845	COG1530	ribonuclease E activity
F6X00_RS05850	COG3164	Protein of unknown function
F6X00_RS05855	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
F6X00_RS05860	COG0312	modulator of DNA gyrase
F6X00_RS05865	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
F6X00_RS05880	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
F6X00_RS05885	COG0251	oxidation-reduction process
F6X00_RS05890	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
F6X00_RS05905	COG2235	arginine
F6X00_RS05990	COG0456	acetyltransferase
F6X00_RS06000	COG4269	membrane
F6X00_RS06010	COG0525	valine-tRNA ligase activity
F6X00_RS06015	COG2927	DNA polymerase III (CHI subunit)
F6X00_RS06020	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
F6X00_RS06025	COG0795	lipopolysaccharide-transporting ATPase activity
F6X00_RS06030	COG0795	lipopolysaccharide-transporting ATPase activity
F6X00_RS06045	COG0726	polysaccharide deacetylase
F6X00_RS06050	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
F6X00_RS06060	COG1447	Phosphotransferase system cellobiose-specific component IIA
F6X00_RS06065	COG1486	melibiose metabolic process
F6X00_RS06075	COG1609	Transcriptional regulator
F6X00_RS06085	COG3437	response regulator, receiver
F6X00_RS06190	COG0741	lytic transglycosylase activity
F6X00_RS06195	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
F6X00_RS06205	COG0220	tRNA (guanine-N7-)-methyltransferase activity
F6X00_RS06210	COG2066	Belongs to the glutaminase family
F6X00_RS06220	COG0635	Involved in the biosynthesis of porphyrin-containing compound
F6X00_RS06225	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
F6X00_RS06235	COG1872	DUF167
F6X00_RS06240	COG0762	integral membrane protein
F6X00_RS06245	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
F6X00_RS06250	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
F6X00_RS06265	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
F6X00_RS06270	COG1678	Uncharacterized ACR, COG1678
F6X00_RS06280	COG1385	rRNA (uridine-N3-)-methyltransferase activity
F6X00_RS06290	COG2356	endonuclease I
F6X00_RS06305	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
F6X00_RS06310	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
F6X00_RS06325	COG0126	phosphoglycerate kinase activity
F6X00_RS06330	COG0191	fructose-bisphosphate aldolase activity
F6X00_RS06335	COG0668	transmembrane transport
F6X00_RS06340	COG1279	arginine transmembrane transporter activity
F6X00_RS06355	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
F6X00_RS06360	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
F6X00_RS06365	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
F6X00_RS06375	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
F6X00_RS06380	COG3079	Belongs to the UPF0149 family
F6X00_RS06385	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F6X00_RS06390	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F6X00_RS06405	COG0354	folic acid binding
F6X00_RS06420	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
F6X00_RS06425	COG1595	DNA-templated transcription, initiation
F6X00_RS06440	COG3086	response to oxidative stress
F6X00_RS06445	COG0481	GTPase activity
F6X00_RS06455	COG0571	ribonuclease III activity
F6X00_RS06460	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
F6X00_RS06465	COG1381	Involved in DNA repair and RecF pathway recombination
F6X00_RS06470	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
F6X00_RS06495	COG4999	Histidine kinase
F6X00_RS06495	COG3850	Histidine kinase
F6X00_RS06495	COG3437	response regulator, receiver
F6X00_RS06495	COG2205	protein histidine kinase activity
F6X00_RS06500	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
F6X00_RS06505	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
F6X00_RS06510	COG3956	TIGRFAM MazG family protein
F6X00_RS06515	COG0504	CTP synthase activity
F6X00_RS06525	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
F6X00_RS06535	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
F6X00_RS06550	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
F6X00_RS06555	COG1388	LysM domain
F6X00_RS06555	COG4942	peptidase
F6X00_RS06560	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
F6X00_RS06565	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
F6X00_RS06575	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
F6X00_RS06580	COG2137	regulation of response to DNA damage stimulus
F6X00_RS06585	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
F6X00_RS06590	COG0527	aspartate kinase activity
F6X00_RS06595	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
F6X00_RS06640	COG3630	sodium ion export across plasma membrane
F6X00_RS06645	COG5016	pyruvate
F6X00_RS06645	COG0511	ligase activity, forming carbon-carbon bonds
F6X00_RS06650	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
F6X00_RS06660	COG1238	metal cluster binding
F6X00_RS06665	COG0612	Peptidase, M16
F6X00_RS06670	COG2918	glutathione biosynthetic process
F6X00_RS06680	COG1854	S-ribosylhomocysteine lyase activity
F6X00_RS06685	COG4536	flavin adenine dinucleotide binding
F6X00_RS06690	COG4137	Cytochrome C assembly protein
F6X00_RS06695	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
F6X00_RS06700	COG0228	four-way junction DNA binding
F6X00_RS06705	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
F6X00_RS06710	COG0336	Belongs to the RNA methyltransferase TrmD family
F6X00_RS06715	COG0335	large ribosomal subunit rRNA binding
F6X00_RS06720	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
F6X00_RS06740	COG1459	type II secretion system
F6X00_RS06745	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
F6X00_RS06755	COG0157	Belongs to the NadC ModD family
F6X00_RS06760	COG3023	N-Acetylmuramoyl-L-alanine amidase
F6X00_RS06765	COG2186	Transcriptional regulator
F6X00_RS06770	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
F6X00_RS06775	COG0508	dehydrogenase complex catalyzes the overall conversion of
F6X00_RS06780	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
F6X00_RS06795	COG0288	reversible hydration of carbon dioxide
F6X00_RS06800	COG0659	secondary active sulfate transmembrane transporter activity
F6X00_RS06805	COG1131	(ABC) transporter
F6X00_RS06810	COG0842	Transport permease protein
F6X00_RS06820	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
F6X00_RS06825	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
F6X00_RS06835	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
F6X00_RS06840	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
F6X00_RS06845	COG1489	DNA binding
F6X00_RS06850	COG1643	Atp-dependent helicase
F6X00_RS06855	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
F6X00_RS06860	COG1752	Esterase of the alpha-beta hydrolase superfamily
F6X00_RS06865	COG1049	propionate catabolic process, 2-methylcitrate cycle
F6X00_RS06870	COG1929	Belongs to the glycerate kinase type-1 family
F6X00_RS06875	COG2610	gluconate transmembrane transporter activity
F6X00_RS06880	COG3835	regulator
F6X00_RS06885	COG3112	Uncharacterised protein family (UPF0231)
F6X00_RS06890	COG0347	Belongs to the P(II) protein family
F6X00_RS06895	COG0004	ammonium transporteR
F6X00_RS06900	COG1840	ABC-type Fe3 transport system, periplasmic component
F6X00_RS06915	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
F6X00_RS06930	COG2971	BadF BadG BcrA BcrD
F6X00_RS06940	COG4608	Belongs to the ABC transporter superfamily
F6X00_RS06945	COG0444	Belongs to the ABC transporter superfamily
F6X00_RS06950	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F6X00_RS06955	COG0601	transmembrane transport
F6X00_RS06965	COG0784	Response regulator, receiver
F6X00_RS06965	COG2205	protein histidine kinase activity
F6X00_RS06970	COG2813	Specifically methylates the guanine in position
F6X00_RS06975	COG0628	permease
F6X00_RS06985	COG0316	Belongs to the HesB IscA family
F6X00_RS07000	COG0739	heme binding
F6X00_RS07005	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
F6X00_RS07010	COG2832	Protein of unknown function (DUF454)
F6X00_RS07015	COG2027	D-alanyl-D-alanine carboxypeptidase
F6X00_RS07020	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
F6X00_RS07030	COG1534	Rna-binding protein
F6X00_RS07035	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
F6X00_RS07040	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
F6X00_RS07045	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
F6X00_RS07050	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
F6X00_RS07055	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
F6X00_RS07070	COG0779	Required for maturation of 30S ribosomal subunits
F6X00_RS07075	COG0195	Participates in both transcription termination and antitermination
F6X00_RS07080	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
F6X00_RS07085	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
F6X00_RS07090	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
F6X00_RS07095	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
F6X00_RS07130	COG1185	polyribonucleotide nucleotidyltransferase activity
F6X00_RS07145	COG0534	Mate efflux family protein
F6X00_RS07150	COG0826	peptidase U32
F6X00_RS07155	COG0826	peptidase U32
F6X00_RS07165	COG3154	lipid carrier protein
F6X00_RS07170	COG3153	acetyltransferase
F6X00_RS07180	COG0456	acetyltransferase
F6X00_RS07190	COG3706	GGDEF domain
F6X00_RS07205	COG0084	hydrolase, TatD family'
F6X00_RS07210	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
F6X00_RS07215	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
F6X00_RS07220	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
F6X00_RS07225	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
F6X00_RS07230	COG0813	purine-nucleoside phosphorylase activity
F6X00_RS07240	COG0560	Phosphoserine phosphatase
F6X00_RS07250	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
F6X00_RS07255	COG3447	MASE1 domain protein
F6X00_RS07255	COG5002	protein histidine kinase activity
F6X00_RS07255	COG5001	Diguanylate cyclase
F6X00_RS07270	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
F6X00_RS07275	COG1022	Amp-dependent synthetase and ligase
F6X00_RS07310	COG4964	Belongs to the GSP D family
F6X00_RS07360	COG2059	Chromate
F6X00_RS07365	COG0583	DNA-binding transcription factor activity
F6X00_RS07375	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
F6X00_RS07375	COG3408	Glycogen debranching enzyme
F6X00_RS07380	COG0531	amino acid
F6X00_RS07385	COG0531	amino acid
F6X00_RS07390	COG2731	YhcH YjgK YiaL family protein
F6X00_RS07395	COG3250	beta-galactosidase activity
F6X00_RS07405	COG1609	Transcriptional regulator
F6X00_RS07410	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
F6X00_RS07415	COG1085	galactose-1-phosphate uridylyltransferase
F6X00_RS07425	COG2017	converts alpha-aldose to the beta-anomer
F6X00_RS07430	COG0840	transmembrane signaling receptor activity
F6X00_RS07440	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
F6X00_RS07455	COG0569	domain protein
F6X00_RS07455	COG0189	ligase activity
F6X00_RS07470	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
F6X00_RS07475	COG1349	DNA-binding transcription factor activity
F6X00_RS07480	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
F6X00_RS07485	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
F6X00_RS07490	COG2171	N-acyltransferase activity
F6X00_RS07495	COG3141	response to X-ray
F6X00_RS07510	COG3083	sulfuric ester hydrolase activity
F6X00_RS07515	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
F6X00_RS07520	COG1074	ATP-dependent DNA helicase activity
F6X00_RS07525	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
F6X00_RS07545	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
F6X00_RS07550	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
F6X00_RS07555	COG2166	iron-sulfur cluster assembly
F6X00_RS07560	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
F6X00_RS07565	COG0693	protein deglycase activity
F6X00_RS07570	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
F6X00_RS07575	COG3248	Nucleoside-binding outer membrane protein
F6X00_RS07585	COG1595	DNA-templated transcription, initiation
F6X00_RS07595	COG2211	Major facilitator Superfamily
F6X00_RS07610	COG2813	Specifically methylates the guanine in position
F6X00_RS07615	COG0271	Belongs to the BolA IbaG family
F6X00_RS07620	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
F6X00_RS07625	COG1805	sodium ion transport
F6X00_RS07630	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
F6X00_RS07640	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
F6X00_RS07645	COG2871	sodium ion transport
F6X00_RS07650	COG1477	protein flavinylation
F6X00_RS07670	COG0514	ATP-dependent DNA helicase (RecQ)
F6X00_RS07685	COG0733	neurotransmitter:sodium symporter activity
F6X00_RS07710	COG1720	tRNA m6t6A37 methyltransferase activity
F6X00_RS07715	COG0254	rRNA binding
F6X00_RS07725	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
F6X00_RS07755	COG3098	single-species biofilm formation
F6X00_RS07770	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
F6X00_RS07775	COG0024	Methionine aminopeptidase
F6X00_RS07780	COG0052	Belongs to the universal ribosomal protein uS2 family
F6X00_RS07785	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
F6X00_RS07790	COG0528	UMP kinase activity
F6X00_RS07795	COG0233	cytoplasmic translational termination
F6X00_RS07800	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
F6X00_RS07805	COG0575	Belongs to the CDS family
F6X00_RS07810	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
F6X00_RS07815	COG0750	zinc metalloprotease
F6X00_RS07820	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
F6X00_RS07825	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
F6X00_RS07835	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
F6X00_RS07840	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
F6X00_RS07845	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
F6X00_RS07850	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
F6X00_RS07855	COG0587	DNA-directed DNA polymerase activity
F6X00_RS07860	COG0825	malonyl-CoA metabolic process
F6X00_RS07865	COG0037	tRNA processing
F6X00_RS07875	COG0347	Belongs to the P(II) protein family
F6X00_RS07880	COG3021	interspecies interaction between organisms
F6X00_RS07890	COG1388	LysM domain
F6X00_RS07890	COG0741	lytic transglycosylase activity
F6X00_RS07895	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F6X00_RS07900	COG2226	methyltransferase
F6X00_RS07905	COG0328	RNA-DNA hybrid ribonuclease activity
F6X00_RS07940	COG1960	acyl-CoA dehydrogenase activity
F6X00_RS07950	COG0121	glutamine amidotransferase
F6X00_RS07955	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
F6X00_RS07960	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
F6X00_RS07965	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
F6X00_RS07970	COG2233	PERMEase
F6X00_RS07990	COG1393	Belongs to the ArsC family
F6X00_RS07995	COG4783	chaperone-mediated protein folding
F6X00_RS08010	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
F6X00_RS08015	COG2716	regulation of RNA biosynthetic process
F6X00_RS08020	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F6X00_RS08045	COG1393	Belongs to the ArsC family
F6X00_RS08070	COG2837	iron assimilation
F6X00_RS08075	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
F6X00_RS08080	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
F6X00_RS08085	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
F6X00_RS08090	COG1334	flagellar protein FlaG
F6X00_RS08095	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
F6X00_RS08105	COG1516	flagellar protein fliS
F6X00_RS08115	COG4191	Histidine kinase
F6X00_RS08125	COG1677	Flagellar hook-basal body complex protein FliE
F6X00_RS08135	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
F6X00_RS08185	COG1987	bacterial-type flagellum assembly
F6X00_RS08190	COG1684	flagellar biosynthetic protein fliR
F6X00_RS08225	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
F6X00_RS08230	COG0784	Response regulator, receiver
F6X00_RS08230	COG2198	Histidine kinase
F6X00_RS08230	COG0643	Histidine kinase
F6X00_RS08240	COG1192	Involved in chromosome partitioning
F6X00_RS08250	COG0835	chemotaxis
F6X00_RS08260	COG4133	protoheme IX ABC transporter activity
F6X00_RS08265	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
F6X00_RS08270	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
F6X00_RS08275	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
F6X00_RS08280	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
F6X00_RS08285	COG1138	Cytochrome C-type biogenesis protein
F6X00_RS08290	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
F6X00_RS08295	COG3088	subunit of a heme lyase
F6X00_RS08295	COG4235	cytochrome complex assembly
F6X00_RS08305	COG2853	Lipoprotein
F6X00_RS08310	COG2067	long-chain fatty acid transport protein
F6X00_RS08315	COG2067	long-chain fatty acid transport protein
F6X00_RS08335	COG1024	Enoyl-CoA hydratase
F6X00_RS08335	COG1250	3-hydroxyacyl-CoA dehydrogenase
F6X00_RS08340	COG1025	Belongs to the peptidase M16 family
F6X00_RS08345	COG2062	phosphohistidine phosphatase, SixA
F6X00_RS08350	COG2840	Smr protein MutS2
F6X00_RS08355	COG2890	protein-(glutamine-N5) methyltransferase activity
F6X00_RS08360	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
F6X00_RS08365	COG2860	membrane
F6X00_RS08370	COG3101	peptidyl-lysine hydroxylation
F6X00_RS08385	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
F6X00_RS08395	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
F6X00_RS08405	COG0101	tRNA pseudouridine synthase activity
F6X00_RS08410	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
F6X00_RS08415	COG0285	dihydrofolate synthase activity
F6X00_RS08420	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
F6X00_RS08425	COG1286	toxin biosynthetic process
F6X00_RS08430	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
F6X00_RS08435	COG0583	DNA-binding transcription factor activity
F6X00_RS08440	COG0745	RESPONSE REGULATOR receiver
F6X00_RS08445	COG2832	Protein of unknown function (DUF454)
F6X00_RS08450	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
F6X00_RS08460	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
F6X00_RS08465	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
F6X00_RS08480	COG2205	protein histidine kinase activity
F6X00_RS08485	COG0745	RESPONSE REGULATOR receiver
F6X00_RS08500	COG2983	Belongs to the UPF0260 family
F6X00_RS08510	COG0346	lactoylglutathione lyase activity
F6X00_RS08520	COG1785	Belongs to the alkaline phosphatase family
F6X00_RS08535	COG2226	methyltransferase
F6X00_RS08540	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
F6X00_RS08550	COG2239	Acts as a magnesium transporter
F6X00_RS08555	COG2203	Gaf domain
F6X00_RS08555	COG2199	diguanylate cyclase activity
F6X00_RS08570	COG3710	Transcriptional regulator
F6X00_RS08575	COG0531	amino acid
F6X00_RS08580	COG1982	Orn Lys Arg decarboxylase major
F6X00_RS08585	COG3706	GGDEF domain
F6X00_RS08590	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
F6X00_RS08590	COG0517	IMP dehydrogenase activity
F6X00_RS08590	COG0617	tRNA 3'-terminal CCA addition
F6X00_RS08615	COG0537	adenosine 5'-monophosphoramidase activity
F6X00_RS08645	COG1252	NADH dehydrogenase
F6X00_RS08660	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
F6X00_RS08670	COG4591	ABC-type transport system involved in lipoprotein release permease component
F6X00_RS08675	COG1136	(ABC) transporter
F6X00_RS08680	COG4591	ABC-type transport system involved in lipoprotein release permease component
F6X00_RS08690	COG0658	competence protein
F6X00_RS08690	COG2333	competence protein COMEC
F6X00_RS08700	COG1663	tetraacyldisaccharide 4'-kinase activity
F6X00_RS08705	COG2835	tetraacyldisaccharide 4'-kinase activity
F6X00_RS08710	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
F6X00_RS08715	COG2199	diguanylate cyclase activity
F6X00_RS08720	COG2719	SpoVR family
F6X00_RS08725	COG2718	Belongs to the UPF0229 family
F6X00_RS08730	COG2766	serine protein kinase
F6X00_RS08735	COG3713	MltA-interacting MipA family protein
F6X00_RS08740	COG3013	Belongs to the UPF0304 family
F6X00_RS08750	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
F6X00_RS08765	COG1882	Formate acetyltransferase
F6X00_RS08805	COG0708	Exodeoxyribonuclease III
F6X00_RS08925	COG4695	Portal protein
F6X00_RS09055	COG0840	transmembrane signaling receptor activity
F6X00_RS09065	COG3923	Primosomal replication protein n
F6X00_RS09075	COG1199	ATP-dependent helicase activity
F6X00_RS09080	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
F6X00_RS09100	COG1278	Cold shock
F6X00_RS09105	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
F6X00_RS09110	COG0542	response to heat
F6X00_RS09115	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
F6X00_RS09135	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
F6X00_RS09145	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
F6X00_RS09150	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
F6X00_RS09175	COG3070	regulator of competence-specific genes
F6X00_RS09180	COG1609	Transcriptional regulator
F6X00_RS09185	COG3381	protein complex oligomerization
F6X00_RS09190	COG0745	RESPONSE REGULATOR receiver
F6X00_RS09195	COG1434	Gram-negative-bacterium-type cell wall biogenesis
F6X00_RS09200	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
F6X00_RS09205	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
F6X00_RS09210	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
F6X00_RS09215	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
F6X00_RS09245	COG0189	ligase activity
F6X00_RS09245	COG4067	protein conserved in archaea
F6X00_RS09250	COG0500	methyltransferase
F6X00_RS09255	COG4106	trans-aconitate 2-methyltransferase activity
F6X00_RS09265	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
F6X00_RS09275	COG0840	transmembrane signaling receptor activity
F6X00_RS09280	COG0632	four-way junction helicase activity
F6X00_RS09285	COG2255	four-way junction helicase activity
F6X00_RS09290	COG1271	oxidase subunit
F6X00_RS09295	COG1294	oxidase, subunit
F6X00_RS09300	COG4890	Cyd operon protein YbgT
F6X00_RS09310	COG0824	Thioesterase
F6X00_RS09315	COG0811	peptide transport
F6X00_RS09330	COG0823	Involved in the tonB-independent uptake of proteins
F6X00_RS09335	COG2885	chlorophyll binding
F6X00_RS09340	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
F6X00_RS09355	COG3766	membrane
F6X00_RS09365	COG0754	glutathionylspermidine amidase activity
F6X00_RS09375	COG2205	protein histidine kinase activity
F6X00_RS09375	COG0784	Response regulator, receiver
F6X00_RS09425	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
F6X00_RS09440	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
F6X00_RS09445	COG0840	transmembrane signaling receptor activity
F6X00_RS09450	COG1349	DNA-binding transcription factor activity
F6X00_RS09455	COG0738	Major facilitator superfamily
F6X00_RS09460	COG2407	Converts the aldose L-fucose into the corresponding ketose L-fuculose
F6X00_RS09465	COG1070	Carbohydrate kinase
F6X00_RS09470	COG4154	Belongs to the RbsD FucU family
F6X00_RS09475	COG0235	Class ii aldolase
F6X00_RS09480	COG1454	alcohol dehydrogenase
F6X00_RS09485	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
F6X00_RS09490	COG0861	Integral membrane protein TerC family
F6X00_RS09510	COG2207	Transcriptional regulator
F6X00_RS09530	COG1032	radical SAM domain protein
F6X00_RS09555	COG0583	DNA-binding transcription factor activity
F6X00_RS09565	COG0857	belongs to the CobB CobQ family
F6X00_RS09565	COG0280	phosphate acetyltransferase
F6X00_RS09570	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
F6X00_RS09575	COG3092	negative regulation of chromosome organization
F6X00_RS09585	COG4120	Belongs to the binding-protein-dependent transport system permease family
F6X00_RS09595	COG0366	Alpha amylase catalytic
F6X00_RS09600	COG2199	diguanylate cyclase activity
F6X00_RS09610	COG3318	Belongs to the UPF0149 family
F6X00_RS09610	COG3012	SEC-C Motif Domain Protein
F6X00_RS09620	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
F6X00_RS09625	COG2186	Transcriptional regulator
F6X00_RS09655	COG2989	Protein conserved in bacteria
F6X00_RS09660	COG3108	Peptidase M15
F6X00_RS09665	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F6X00_RS09680	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
F6X00_RS09705	COG1846	Transcriptional regulator
F6X00_RS09710	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
F6X00_RS09715	COG0840	transmembrane signaling receptor activity
F6X00_RS09735	COG1448	Aminotransferase
F6X00_RS09740	COG3437	response regulator, receiver
F6X00_RS09740	COG2770	Histidine kinase
F6X00_RS09755	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F6X00_RS09765	COG0017	Asparaginyl-tRNA synthetase
F6X00_RS09770	COG0840	transmembrane signaling receptor activity
F6X00_RS09775	COG0720	synthase
F6X00_RS09785	COG2200	EAL domain
F6X00_RS09790	COG1760	l-serine dehydratase
F6X00_RS09795	COG0814	amino acid
F6X00_RS09800	COG0494	nUDIX hydrolase
F6X00_RS09810	COG0784	Response regulator, receiver
F6X00_RS09810	COG2205	protein histidine kinase activity
F6X00_RS09820	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
F6X00_RS09835	COG3106	COG3106 Predicted ATPase
F6X00_RS09840	COG3768	UPF0283 membrane protein
F6X00_RS09845	COG3283	Transcriptional regulator of aromatic amino acids metabolism
F6X00_RS09850	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F6X00_RS09865	COG0471	metal ion transport
F6X00_RS09870	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F6X00_RS09870	COG4191	Histidine kinase
F6X00_RS09880	COG3706	GGDEF domain
F6X00_RS09885	COG2199	diguanylate cyclase activity
F6X00_RS09885	COG2200	EAL domain
F6X00_RS09900	COG5001	Diguanylate cyclase
F6X00_RS09900	COG3300	MHYT domain
F6X00_RS09905	COG1328	CTP reductase activity
F6X00_RS09910	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
F6X00_RS09915	COG0583	DNA-binding transcription factor activity
F6X00_RS09930	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
F6X00_RS09935	COG4667	esterase of the alpha-beta hydrolase superfamily
F6X00_RS09945	COG1597	lipid kinase activity
F6X00_RS09950	COG0814	amino acid
F6X00_RS09965	COG0783	Belongs to the Dps family
F6X00_RS09980	COG1132	(ABC) transporter
F6X00_RS09985	COG1132	(ABC) transporter
F6X00_RS09990	COG1115	amino acid carrier protein
F6X00_RS10005	COG1596	polysaccharide export
F6X00_RS10030	COG0438	transferase activity, transferring glycosyl groups
F6X00_RS10035	COG0438	transferase activity, transferring glycosyl groups
F6X00_RS10035	COG0297	glycogen (starch) synthase activity
F6X00_RS10080	COG0443	Heat shock 70 kDa protein
F6X00_RS10085	COG0443	Heat shock 70 kDa protein
F6X00_RS10095	COG3706	GGDEF domain
F6X00_RS10115	COG3713	MltA-interacting MipA family protein
F6X00_RS10145	COG4964	Belongs to the GSP D family
F6X00_RS10155	COG2894	cell division
F6X00_RS10195	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
F6X00_RS10205	COG1643	Atp-dependent helicase
F6X00_RS10230	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
F6X00_RS10240	COG2814	Major facilitator Superfamily
F6X00_RS10255	COG0840	transmembrane signaling receptor activity
F6X00_RS10260	COG0010	Belongs to the arginase family
F6X00_RS10265	COG1166	arginine decarboxylase activity
F6X00_RS10330	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
F6X00_RS10335	COG0072	phenylalanine-tRNA ligase activity
F6X00_RS10335	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
F6X00_RS10355	COG0776	regulation of translation
F6X00_RS10365	COG0500	methyltransferase
F6X00_RS10370	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
F6X00_RS10375	COG0295	cytidine deaminase activity
F6X00_RS10390	COG2885	chlorophyll binding
F6X00_RS10405	COG0247	lactate metabolic process
F6X00_RS10405	COG0277	FAD linked oxidase domain protein
F6X00_RS10410	COG2020	methyltransferase activity
F6X00_RS10425	COG2986	histidine ammonia-lyase
F6X00_RS10435	COG0010	Belongs to the arginase family
F6X00_RS10440	COG1228	amidohydrolase
F6X00_RS10450	COG4326	sporulation control protein
F6X00_RS10470	COG0291	Belongs to the bacterial ribosomal protein bL35 family
F6X00_RS10600	COG4628	conserved protein (DUF2132)
F6X00_RS10780	COG0625	glutathione transferase activity
F6X00_RS10860	COG0384	phenazine biosynthesis protein PhzF
F6X00_RS10910	COG0384	phenazine biosynthesis protein PhzF
F6X00_RS10965	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
F6X00_RS11005	COG0454	-acetyltransferase
F6X00_RS11020	COG2026	Addiction module toxin, RelE StbE family
F6X00_RS11220	COG2026	Addiction module toxin, RelE StbE family
F6X00_RS11410	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
F6X00_RS11415	COG2944	sequence-specific DNA binding
F6X00_RS11480	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F6X00_RS11560	COG1028	Short-chain dehydrogenase reductase Sdr
F6X00_RS11575	COG2161	toxin-antitoxin pair type II binding
F6X00_RS11580	COG4115	mRNA cleavage
F6X00_RS11590	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
F6X00_RS11595	COG2944	sequence-specific DNA binding
F6X00_RS11640	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
F6X00_RS11640	COG0456	acetyltransferase
F6X00_RS11645	COG0625	glutathione transferase activity
F6X00_RS11765	COG1942	4-Oxalocrotonate Tautomerase
F6X00_RS11800	COG0582	viral genome integration into host DNA
F6X00_RS12075	COG0346	lactoylglutathione lyase activity
F6X00_RS12225	COG0346	lactoylglutathione lyase activity
F6X00_RS12235	COG0251	oxidation-reduction process
F6X00_RS12310	COG0534	Mate efflux family protein
F6X00_RS12315	COG0307	riboflavin synthase, alpha
F6X00_RS12335	COG3706	GGDEF domain
F6X00_RS12345	COG0791	NLP P60 protein
F6X00_RS12350	COG0840	transmembrane signaling receptor activity
F6X00_RS12365	COG1940	carbohydrate kinase activity
F6X00_RS12380	COG0746	molybdenum cofactor guanylyltransferase activity
F6X00_RS12385	COG3842	ATPase activity
F6X00_RS12390	COG4662	Binding-protein-dependent transport system inner membrane component
F6X00_RS12400	COG2204	response regulator
F6X00_RS12405	COG3852	Histidine kinase
F6X00_RS12420	COG0488	(ABC) transporter
F6X00_RS12430	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
F6X00_RS12460	COG3383	formate dehydrogenase (NAD+) activity
F6X00_RS12460	COG0243	molybdopterin cofactor binding
F6X00_RS12465	COG0437	4 iron, 4 sulfur cluster binding
F6X00_RS12500	COG0004	ammonium transporteR
F6X00_RS12505	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
F6X00_RS12510	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
F6X00_RS12520	COG1177	transmembrane transport
F6X00_RS12525	COG1176	ABC-type spermidine putrescine transport system, permease component I
F6X00_RS12530	COG3842	ATPase activity
F6X00_RS12540	COG2992	FlgJ-related protein
F6X00_RS12550	COG0037	tRNA processing
F6X00_RS12555	COG0589	response to stress
F6X00_RS12560	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
F6X00_RS12575	COG2217	Heavy metal translocating P-type atpase
F6X00_RS12585	COG2010	Cytochrome c
F6X00_RS12600	COG3278	Belongs to the heme-copper respiratory oxidase family
F6X00_RS12615	COG0784	Response regulator, receiver
F6X00_RS12615	COG2205	protein histidine kinase activity
F6X00_RS12665	COG1450	Type ii and iii secretion system protein
F6X00_RS12690	COG3120	sequence-specific DNA binding
F6X00_RS12695	COG1067	ATP-dependent peptidase activity
F6X00_RS12700	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
F6X00_RS12715	COG0488	(ABC) transporter
F6X00_RS12725	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
F6X00_RS12725	COG0116	Belongs to the methyltransferase superfamily
F6X00_RS12740	COG2902	Dehydrogenase
F6X00_RS12750	COG0308	aminopeptidase N
F6X00_RS12765	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
F6X00_RS12770	COG1956	GAF domain-containing protein
F6X00_RS12775	COG1132	(ABC) transporter
F6X00_RS12780	COG2995	paraquat-inducible protein a
F6X00_RS12785	COG3008	intermembrane lipid transfer
F6X00_RS12790	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
F6X00_RS12790	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
F6X00_RS12795	COG2996	Protein conserved in bacteria
F6X00_RS12810	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
F6X00_RS12820	COG3706	GGDEF domain
F6X00_RS12825	COG1793	dna ligase
F6X00_RS12830	COG1366	Belongs to the anti-sigma-factor antagonist family
F6X00_RS12860	COG2204	response regulator
F6X00_RS12905	COG0438	transferase activity, transferring glycosyl groups
F6X00_RS12915	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
F6X00_RS12960	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
F6X00_RS12965	COG0363	glucosamine-6-phosphate deaminase activity
F6X00_RS12970	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
F6X00_RS12975	COG4565	transcriptional regulatory protein
F6X00_RS12980	COG3290	protein histidine kinase activity
F6X00_RS12995	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F6X00_RS13025	COG1115	amino acid carrier protein
F6X00_RS13040	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
F6X00_RS13045	COG0204	Acyl-transferase
F6X00_RS13050	COG0348	domain, Protein
F6X00_RS13055	COG0437	4 iron, 4 sulfur cluster binding
F6X00_RS13065	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F6X00_RS13070	COG4597	amino acid ABC transporter
F6X00_RS13075	COG0765	amino acid transport
F6X00_RS13080	COG1126	abc transporter atp-binding protein
F6X00_RS13085	COG0670	Belongs to the BI1 family
F6X00_RS13095	COG2920	part of a sulfur-relay system
F6X00_RS13110	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
F6X00_RS13135	COG3706	GGDEF domain
F6X00_RS13140	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
F6X00_RS13145	COG0602	queuosine metabolic process
F6X00_RS13150	COG0561	phosphatase activity
F6X00_RS13185	COG2828	Protein conserved in bacteria
F6X00_RS13190	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
F6X00_RS13195	COG0372	Belongs to the citrate synthase family
F6X00_RS13200	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
F6X00_RS13210	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
F6X00_RS13250	COG2197	response regulator
F6X00_RS13260	COG0730	response to heat
F6X00_RS13275	COG1653	transport
F6X00_RS13280	COG1175	transmembrane transport
F6X00_RS13285	COG0395	ABC-type sugar transport system, permease component
F6X00_RS13295	COG1349	DNA-binding transcription factor activity
F6X00_RS13300	COG0584	glycerophosphoryl diester phosphodiesterase
F6X00_RS13315	COG1278	Cold shock
F6X00_RS13355	COG0625	glutathione transferase activity
F6X00_RS13365	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
F6X00_RS13375	COG2195	Cleaves the N-terminal amino acid of tripeptides
F6X00_RS13380	COG0737	Belongs to the 5'-nucleotidase family
F6X00_RS13390	COG3063	Type IV pilus biogenesis stability protein PilW
F6X00_RS13405	COG1451	nucleotide metabolic process
F6X00_RS13415	COG0583	DNA-binding transcription factor activity
F6X00_RS13435	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
F6X00_RS13445	COG2988	succinylglutamate desuccinylase activity
F6X00_RS13465	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
F6X00_RS13480	COG2925	Exonuclease
F6X00_RS13485	COG1380	Effector of murein hydrolase LrgA
F6X00_RS13490	COG1346	cytolysis
F6X00_RS13500	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
F6X00_RS13515	COG1643	Atp-dependent helicase
F6X00_RS13520	COG0281	malic enzyme
F6X00_RS13525	COG2949	membrane
F6X00_RS13530	COG0471	metal ion transport
F6X00_RS13555	COG0492	ferredoxin-NADP+ reductase activity
F6X00_RS13560	COG4988	ABC transporter
F6X00_RS13565	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
F6X00_RS13570	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
F6X00_RS13580	COG5002	protein histidine kinase activity
F6X00_RS13580	COG5002	protein histidine kinase activity
F6X00_RS13595	COG3070	regulator of competence-specific genes
F6X00_RS13605	COG2431	L-lysine efflux transmembrane transporter activity
F6X00_RS13615	COG0076	glutamate decarboxylase activity
F6X00_RS13620	COG1737	Transcriptional regulator
F6X00_RS13625	COG1979	alcohol dehydrogenase
F6X00_RS13630	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
F6X00_RS13635	COG3273	potassium ion transport
F6X00_RS13635	COG2985	domain, Protein
F6X00_RS13640	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
F6X00_RS13655	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
F6X00_RS13670	COG1136	(ABC) transporter
F6X00_RS13675	COG0702	epimerase
F6X00_RS13690	COG2814	Major facilitator Superfamily
F6X00_RS13700	COG1061	Type III restriction enzyme res subunit
F6X00_RS13715	COG2205	protein histidine kinase activity
F6X00_RS13720	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
F6X00_RS13745	COG3313	Fe-S protein
F6X00_RS13755	COG4134	Bacterial extracellular solute-binding protein
F6X00_RS13760	COG4135	transport system, permease component
F6X00_RS13765	COG4136	ATPase activity
F6X00_RS13770	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
F6X00_RS13775	COG3604	Transcriptional regulator
F6X00_RS13780	COG1151	hydroxylamine reductase activity
F6X00_RS13785	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
F6X00_RS13795	COG0564	pseudouridine synthase activity
F6X00_RS13805	COG0733	neurotransmitter:sodium symporter activity
F6X00_RS13815	COG0626	cystathionine gamma-synthase activity
F6X00_RS13820	COG2818	Glycosylase
F6X00_RS13840	COG1983	PspC domain protein
F6X00_RS13850	COG1842	Phage shock protein A
F6X00_RS13855	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
F6X00_RS13880	COG4172	Belongs to the ABC transporter superfamily
F6X00_RS13895	COG1227	inorganic diphosphatase activity
F6X00_RS13925	COG0243	molybdopterin cofactor binding
F6X00_RS13930	COG3005	denitrification pathway
F6X00_RS13935	COG4459	periplasmic nitrate reductase
F6X00_RS13940	COG0390	transport system, permease component
F6X00_RS13945	COG2116	formate transmembrane transporter activity
F6X00_RS13965	COG0583	DNA-binding transcription factor activity
F6X00_RS13970	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F6X00_RS13980	COG1435	thymidine kinase activity
F6X00_RS13990	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
F6X00_RS13995	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
F6X00_RS14000	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
F6X00_RS14005	COG3012	SEC-C Motif Domain Protein
F6X00_RS14010	COG0140	phosphoribosyl-ATP diphosphatase activity
F6X00_RS14010	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
F6X00_RS14015	COG0107	imidazoleglycerol-phosphate synthase activity
F6X00_RS14025	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
F6X00_RS14030	COG0131	Imidazoleglycerol-phosphate dehydratase
F6X00_RS14030	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
F6X00_RS14035	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
F6X00_RS14045	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
F6X00_RS14050	COG1757	Na H antiporter
F6X00_RS14055	COG2916	Histone family protein nucleoid-structuring protein H-NS
F6X00_RS14060	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F6X00_RS14075	COG2915	High frequency lysogenization protein hflD homolog
F6X00_RS14080	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
F6X00_RS14100	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
F6X00_RS14115	COG0300	oxidoreductase activity
F6X00_RS14125	COG0501	Belongs to the peptidase M48B family
F6X00_RS14135	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
F6X00_RS14150	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
F6X00_RS14165	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
F6X00_RS14170	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
F6X00_RS14185	COG0686	Belongs to the AlaDH PNT family
F6X00_RS14195	COG0583	DNA-binding transcription factor activity
F6X00_RS14240	COG4608	Belongs to the ABC transporter superfamily
F6X00_RS14245	COG0444	Belongs to the ABC transporter superfamily
F6X00_RS14250	COG4166	transmembrane transport
F6X00_RS14255	COG4239	(ABC) transporter, permease
F6X00_RS14260	COG4174	ABC transporter (Permease)
F6X00_RS14265	COG0284	orotidine-5'-phosphate decarboxylase activity
F6X00_RS14270	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
F6X00_RS14275	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
F6X00_RS14285	COG0539	negative regulation of cytoplasmic translation
F6X00_RS14295	COG0616	signal peptide processing
F6X00_RS14300	COG1028	Short-chain dehydrogenase reductase Sdr
F6X00_RS14315	COG0587	DNA-directed DNA polymerase activity
F6X00_RS14320	COG0835	chemotaxis
F6X00_RS14320	COG0784	Response regulator, receiver
F6X00_RS14325	COG1940	carbohydrate kinase activity
F6X00_RS14330	COG0469	pyruvate kinase activity
F6X00_RS14335	COG4667	esterase of the alpha-beta hydrolase superfamily
F6X00_RS14350	COG0733	neurotransmitter:sodium symporter activity
F6X00_RS14365	COG1263	PTS System
F6X00_RS14365	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F6X00_RS14370	COG0084	hydrolase, TatD family'
F6X00_RS14380	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
F6X00_RS14385	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
F6X00_RS14400	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
F6X00_RS14415	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
F6X00_RS14420	COG0416	fatty acid biosynthetic process
F6X00_RS14425	COG0333	Belongs to the bacterial ribosomal protein bL32 family
F6X00_RS14430	COG1399	metal-binding, possibly nucleic acid-binding protein
F6X00_RS14435	COG0424	maF-like protein
F6X00_RS14445	COG1530	ribonuclease E activity
F6X00_RS14450	COG0659	secondary active sulfate transmembrane transporter activity
F6X00_RS14455	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
F6X00_RS14460	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
F6X00_RS14470	COG0572	uridine kinase
F6X00_RS14475	COG0489	protein tyrosine kinase activity
F6X00_RS14480	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
F6X00_RS14480	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
F6X00_RS14495	COG3088	subunit of a heme lyase
F6X00_RS14495	COG4235	cytochrome complex assembly
F6X00_RS14500	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
F6X00_RS14505	COG1138	Cytochrome C-type biogenesis protein
F6X00_RS14510	COG3301	Polysulphide reductase, NrfD
F6X00_RS14515	COG0437	4 iron, 4 sulfur cluster binding
F6X00_RS14520	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
F6X00_RS14525	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
F6X00_RS14545	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
F6X00_RS14550	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
F6X00_RS14555	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
F6X00_RS14620	COG0322	excinuclease ABC activity
F6X00_RS14625	COG2197	response regulator
F6X00_RS14630	COG0417	DNA replication proofreading
F6X00_RS14635	COG5001	Diguanylate cyclase
F6X00_RS14645	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
F6X00_RS14665	COG0009	L-threonylcarbamoyladenylate synthase
F6X00_RS14670	COG0613	PHP domain protein
F6X00_RS14680	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
F6X00_RS14685	COG0512	Glutamine amidotransferase of anthranilate synthase
F6X00_RS14695	COG0135	phosphoribosylanthranilate isomerase activity
F6X00_RS14695	COG0134	indole-3-glycerol-phosphate synthase activity
F6X00_RS14700	COG0133	tryptophan synthase activity
F6X00_RS14710	COG1301	dicarboxylic acid transport
F6X00_RS14730	COG2350	Protein conserved in bacteria
F6X00_RS14740	COG0435	Glutathione S-transferase
F6X00_RS14750	COG0444	Belongs to the ABC transporter superfamily
F6X00_RS14755	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F6X00_RS14760	COG0601	transmembrane transport
F6X00_RS14770	COG0314	molybdopterin synthase activity
F6X00_RS14775	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
F6X00_RS14785	COG0521	Mo-molybdopterin cofactor biosynthetic process
F6X00_RS14795	COG0391	Required for morphogenesis under gluconeogenic growth conditions
F6X00_RS14800	COG2198	Histidine kinase
F6X00_RS14805	COG2204	response regulator
F6X00_RS14810	COG0556	nucleotide-excision repair
F6X00_RS14825	COG4657	Part of a membrane complex involved in electron transport
F6X00_RS14830	COG2878	Part of a membrane complex involved in electron transport
F6X00_RS14835	COG4656	Part of a membrane complex involved in electron transport
F6X00_RS14840	COG4658	electron transport chain
F6X00_RS14845	COG4659	FMN binding
F6X00_RS14850	COG4660	Part of a membrane complex involved in electron transport
F6X00_RS14855	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
F6X00_RS14860	COG0346	lactoylglutathione lyase activity
F6X00_RS14870	COG2885	chlorophyll binding
F6X00_RS14875	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
F6X00_RS14880	COG2056	Na+-H+ antiporter family
F6X00_RS14890	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
F6X00_RS14905	COG1028	Short-chain dehydrogenase reductase Sdr
F6X00_RS14910	COG1012	belongs to the aldehyde dehydrogenase family
F6X00_RS14910	COG1454	alcohol dehydrogenase
F6X00_RS14915	COG2095	MarC family integral membrane protein
F6X00_RS14920	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
F6X00_RS14930	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
F6X00_RS14935	COG1757	Na H antiporter
F6X00_RS14950	COG3081	Nucleoid-associated protein
F6X00_RS14960	COG3083	sulfuric ester hydrolase activity
F6X00_RS14985	COG0569	domain protein
F6X00_RS14990	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
F6X00_RS14995	COG2731	YhcH YjgK YiaL family protein
F6X00_RS15000	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
F6X00_RS15010	COG2205	protein histidine kinase activity
F6X00_RS15010	COG0784	Response regulator, receiver
F6X00_RS15015	COG0123	including yeast histone deacetylase and acetoin utilization protein
F6X00_RS15020	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
F6X00_RS15025	COG0778	Nitroreductase
F6X00_RS15030	COG1902	pentaerythritol trinitrate reductase activity
F6X00_RS15030	COG0446	pyridine nucleotide-disulphide oxidoreductase
F6X00_RS15035	COG0616	signal peptide processing
F6X00_RS15040	COG0252	asparaginase activity
F6X00_RS15045	COG3139	Protein of unknown function (DUF1315)
F6X00_RS15060	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
F6X00_RS15095	COG5001	Diguanylate cyclase
F6X00_RS15110	COG3126	Type III secretion system lipoprotein chaperone (YscW)
F6X00_RS15115	COG1946	Acyl-CoA thioesterase
F6X00_RS15125	COG1522	sequence-specific DNA binding
F6X00_RS15130	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
F6X00_RS15165	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F6X00_RS15170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F6X00_RS15225	COG0318	PFAM AMP-dependent synthetase and ligase
F6X00_RS15235	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
F6X00_RS15240	COG0596	Alpha beta hydrolase
F6X00_RS15250	COG1169	isochorismate synthase
F6X00_RS15255	COG0436	Aminotransferase
F6X00_RS15260	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
F6X00_RS15265	COG0232	Belongs to the dGTPase family. Type 2 subfamily
F6X00_RS15280	COG1555	photosystem II stabilization
F6X00_RS15285	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
F6X00_RS15290	COG0776	regulation of translation
F6X00_RS15295	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
F6X00_RS15300	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
F6X00_RS15315	COG4191	Histidine kinase
F6X00_RS15320	COG2204	response regulator
F6X00_RS15330	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
F6X00_RS15335	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
F6X00_RS15340	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
F6X00_RS15345	COG3842	ATPase activity
F6X00_RS15355	COG1175	transmembrane transport
F6X00_RS15370	COG0745	RESPONSE REGULATOR receiver
F6X00_RS15375	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
F6X00_RS15415	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
F6X00_RS15420	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
F6X00_RS15440	COG1216	Glycosyl transferase, family 2
F6X00_RS15445	COG2986	histidine ammonia-lyase
F6X00_RS15470	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
F6X00_RS15480	COG1028	Short-chain dehydrogenase reductase Sdr
F6X00_RS15495	COG5002	protein histidine kinase activity
F6X00_RS15500	COG0745	RESPONSE REGULATOR receiver
F6X00_RS15510	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
F6X00_RS15520	COG2951	lytic endotransglycosylase activity
F6X00_RS15530	COG0850	regulation of cytokinetic process
F6X00_RS15535	COG2894	cell division
F6X00_RS15540	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
F6X00_RS15545	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
F6X00_RS15550	COG0318	PFAM AMP-dependent synthetase and ligase
F6X00_RS15555	COG0596	Alpha beta hydrolase
F6X00_RS15570	COG1214	PFAM Peptidase M22, glycoprotease
F6X00_RS15575	COG1199	ATP-dependent helicase activity
F6X00_RS15585	COG0788	formyltetrahydrofolate deformylase activity
F6X00_RS15590	COG3102	Protein conserved in bacteria
F6X00_RS15610	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
F6X00_RS15615	COG1918	ferrous iron import across plasma membrane
F6X00_RS15625	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
F6X00_RS15630	COG1121	(ABC) transporter
F6X00_RS15635	COG1108	ABC-type Mn2 Zn2 transport systems permease components
F6X00_RS15650	COG0508	dehydrogenase complex catalyzes the overall conversion of
F6X00_RS15655	COG0567	Dehydrogenase, E1 component
F6X00_RS15665	COG1053	succinate dehydrogenase
F6X00_RS15670	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
F6X00_RS15675	COG2009	succinate dehydrogenase
F6X00_RS15685	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
F6X00_RS15695	COG0446	pyridine nucleotide-disulphide oxidoreductase
F6X00_RS15705	COG0251	oxidation-reduction process
F6X00_RS15710	COG2964	Protein conserved in bacteria
F6X00_RS15715	COG0033	Phosphoglucomutase
F6X00_RS15720	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
F6X00_RS15725	COG0596	Alpha beta hydrolase
F6X00_RS15735	COG0716	FMN binding
F6X00_RS15750	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
F6X00_RS15755	COG1263	PTS System
F6X00_RS15755	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F6X00_RS15755	COG2190	(PTS) system
F6X00_RS15760	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
F6X00_RS15765	COG1940	carbohydrate kinase activity
F6X00_RS15765	COG1846	Transcriptional regulator
F6X00_RS15770	COG4651	solute:proton antiporter activity
F6X00_RS15770	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
F6X00_RS15775	COG0367	asparagine synthase
F6X00_RS15785	COG3104	oligopeptide transport
F6X00_RS15790	COG0840	transmembrane signaling receptor activity
F6X00_RS15795	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
F6X00_RS15810	COG3710	Transcriptional regulator
F6X00_RS15830	COG0622	Phosphoesterase
F6X00_RS15855	COG1090	epimerase
F6X00_RS15860	COG0300	oxidoreductase activity
F6X00_RS15865	COG3118	belongs to the thioredoxin family
F6X00_RS15870	COG0330	HflC and HflK could
F6X00_RS15890	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
F6X00_RS15900	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
F6X00_RS15905	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
F6X00_RS15910	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
F6X00_RS15915	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
F6X00_RS15920	COG2190	(PTS) system
F6X00_RS15925	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
F6X00_RS15930	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
F6X00_RS15935	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
F6X00_RS15940	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
F6X00_RS15950	COG1705	Flagellar rod assembly protein muramidase FlgJ
F6X00_RS15950	COG3951	Flagellar rod assembly protein muramidase FlgJ
F6X00_RS15955	COG1706	bacterial-type flagellum-dependent cell motility
F6X00_RS15970	COG4787	bacterial-type flagellum-dependent cell motility
F6X00_RS15975	COG1749	Flagellar hook protein flgE
F6X00_RS15990	COG1815	bacterial-type flagellum-dependent cell motility
F6X00_RS15995	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
F6X00_RS16000	COG0784	Response regulator, receiver
F6X00_RS16000	COG0835	chemotaxis
F6X00_RS16045	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
F6X00_RS16060	COG2608	mercury ion transmembrane transporter activity
F6X00_RS16060	COG2217	Heavy metal translocating P-type atpase
F6X00_RS16075	COG3735	TraB family
F6X00_RS16090	COG2840	Smr protein MutS2
F6X00_RS16095	COG1187	pseudouridine synthase activity
F6X00_RS16110	COG2877	3-deoxy-8-phosphooctulonate synthase activity
F6X00_RS16115	COG2912	Transglutaminase-like superfamily
F6X00_RS16125	COG2890	protein-(glutamine-N5) methyltransferase activity
F6X00_RS16130	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
F6X00_RS16135	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
F6X00_RS16145	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
F6X00_RS16150	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
F6X00_RS16155	COG0193	aminoacyl-tRNA hydrolase activity
F6X00_RS16240	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F6X00_RS16245	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
F6X00_RS16250	COG1702	phosphate starvation-inducible protein PhoH
F6X00_RS16255	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
F6X00_RS16260	COG4535	Mg2 and Co2 transporter CorC
F6X00_RS16265	COG0815	Transfers the fatty acyl group on membrane lipoproteins
F6X00_RS16270	COG2888	peptidyl-tyrosine sulfation
F6X00_RS16280	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
F6X00_RS16285	COG1466	dna polymerase III delta subunit
F6X00_RS16290	COG0799	negative regulation of ribosome biogenesis
F6X00_RS16295	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
F6X00_RS16300	COG0768	penicillin binding
F6X00_RS16305	COG0772	Belongs to the SEDS family
F6X00_RS16310	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
F6X00_RS16315	COG1686	Belongs to the peptidase S11 family
F6X00_RS16320	COG2921	Belongs to the UPF0250 family
F6X00_RS16325	COG0321	lipoyl(octanoyl) transferase activity
F6X00_RS16330	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
F6X00_RS16340	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
F6X00_RS16370	COG0366	Alpha amylase catalytic
F6X00_RS16375	COG1263	PTS System
F6X00_RS16375	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F6X00_RS16385	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
F6X00_RS16390	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
F6X00_RS16395	COG2011	ABC-type metal ion transport system permease component
F6X00_RS16400	COG1464	Belongs to the NlpA lipoprotein family
F6X00_RS16405	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
F6X00_RS16425	COG3706	GGDEF domain
F6X00_RS16430	COG1611	Belongs to the LOG family
F6X00_RS16450	COG2363	Small membrane protein
F6X00_RS16460	COG0583	DNA-binding transcription factor activity
F6X00_RS16475	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
F6X00_RS16475	COG0301	tRNA thio-modification
F6X00_RS16485	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
F6X00_RS16490	COG1722	exodeoxyribonuclease VII activity
F6X00_RS16495	COG0142	geranyltranstransferase activity
F6X00_RS16500	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
F6X00_RS16505	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
F6X00_RS16510	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
F6X00_RS16515	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
F6X00_RS16520	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
F6X00_RS16535	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
F6X00_RS16535	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
F6X00_RS16540	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
F6X00_RS16550	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
F6X00_RS16565	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
F6X00_RS16570	COG2252	PERMEase
F6X00_RS16575	COG2195	Cleaves the N-terminal amino acid of tripeptides
F6X00_RS16605	COG0668	transmembrane transport
F6X00_RS16630	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F6X00_RS16635	COG0793	Belongs to the peptidase S41A family
F6X00_RS16635	COG4946	Tricorn protease homolog
F6X00_RS16655	COG4720	Psort location CytoplasmicMembrane, score
F6X00_RS16660	COG1566	PFAM secretion protein HlyD family protein
F6X00_RS16670	COG3706	GGDEF domain
F6X00_RS16685	COG0813	purine-nucleoside phosphorylase activity
F6X00_RS16690	COG3272	Protein of unknown function (DUF1722)
F6X00_RS16695	COG0789	Transcriptional regulator
F6X00_RS16700	COG0415	Belongs to the DNA photolyase family
F6X00_RS16705	COG1376	ErfK ybiS ycfS ynhG family protein
F6X00_RS16705	COG1388	LysM domain
F6X00_RS16715	COG0513	Belongs to the DEAD box helicase family
F6X00_RS16755	COG0573	inorganic phosphate transmembrane transporter activity
F6X00_RS16760	COG0581	inorganic phosphate transmembrane transporter activity
F6X00_RS16765	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
F6X00_RS16770	COG3706	GGDEF domain
F6X00_RS16770	COG5001	Diguanylate cyclase
F6X00_RS16770	COG2203	Gaf domain
F6X00_RS16770	COG4251	negative regulation of phosphorylation
F6X00_RS16780	COG2304	oxidoreductase activity
F6X00_RS16800	COG0714	Associated with various cellular activities
F6X00_RS16870	COG1596	polysaccharide export
F6X00_RS16880	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
F6X00_RS16885	COG3842	ATPase activity
F6X00_RS16895	COG1175	transmembrane transport
F6X00_RS16900	COG3833	ABC-type maltose transport systems, permease component
F6X00_RS16930	COG2354	Protein conserved in bacteria
F6X00_RS16940	COG0418	dihydroorotase activity
F6X00_RS16945	COG0633	Ferredoxin
F6X00_RS16945	COG3217	Mosc domain protein beta barrel domain protein
F6X00_RS16945	COG0633	Ferredoxin
F6X00_RS16945	COG3217	Mosc domain protein beta barrel domain protein
F6X00_RS16950	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
F6X00_RS16995	COG3385	transposase activity
F6X00_RS17005	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F6X00_RS17015	COG0848	biopolymer transport protein
F6X00_RS17020	COG0811	peptide transport
F6X00_RS17025	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
F6X00_RS17035	COG3721	Heme iron utilization protein
F6X00_RS17040	COG0748	coenzyme F420 binding
F6X00_RS17050	COG0784	Response regulator, receiver
F6X00_RS17050	COG0835	chemotaxis
F6X00_RS17055	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
F6X00_RS17060	COG0589	response to stress
F6X00_RS17065	COG0366	Alpha amylase catalytic
F6X00_RS17075	COG0840	transmembrane signaling receptor activity
F6X00_RS17110	COG0739	heme binding
F6X00_RS17130	COG2084	Dehydrogenase
F6X00_RS17155	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
F6X00_RS17175	COG0840	transmembrane signaling receptor activity
F6X00_RS17190	COG3706	GGDEF domain
F6X00_RS17195	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
F6X00_RS17195	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
F6X00_RS17200	COG1765	OsmC-like protein
F6X00_RS17230	COG1765	OsmC-like protein
F6X00_RS17255	COG1011	Hydrolase
F6X00_RS17280	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F6X00_RS17285	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
F6X00_RS17285	COG2207	Transcriptional regulator
F6X00_RS17300	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
F6X00_RS17305	COG1840	ABC-type Fe3 transport system, periplasmic component
F6X00_RS17310	COG3842	ATPase activity
F6X00_RS17330	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F6X00_RS17335	COG0583	DNA-binding transcription factor activity
F6X00_RS17345	COG3104	oligopeptide transport
F6X00_RS17355	COG1760	l-serine dehydratase
F6X00_RS17375	COG1686	Belongs to the peptidase S11 family
F6X00_RS17395	COG1309	transcriptional regulator
F6X00_RS17400	COG1012	belongs to the aldehyde dehydrogenase family
F6X00_RS17420	COG4175	Glycine betaine
F6X00_RS17425	COG3059	membrane
F6X00_RS17440	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
F6X00_RS17460	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
F6X00_RS17470	COG0247	lactate metabolic process
F6X00_RS17475	COG0546	phosphoglycolate phosphatase activity
F6X00_RS17485	COG1619	proteins homologs of microcin C7 resistance protein MccF
F6X00_RS17490	COG2133	pyrroloquinoline quinone binding
F6X00_RS17500	COG1454	alcohol dehydrogenase
F6X00_RS17505	COG0443	Heat shock 70 kDa protein
F6X00_RS17510	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
F6X00_RS17540	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F6X00_RS17545	COG3174	membrane
F6X00_RS17570	COG0814	amino acid
F6X00_RS17575	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
F6X00_RS17600	COG2962	Rard protein
F6X00_RS17615	COG0671	phosphoesterase, PA-phosphatase related
F6X00_RS17625	COG1288	antiporter activity
F6X00_RS17640	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
F6X00_RS17655	COG2425	protein containing a von Willebrand factor type A (vWA) domain
F6X00_RS17660	COG2315	Protein conserved in bacteria
F6X00_RS17675	COG1869	D-ribose catabolic process
F6X00_RS17685	COG1172	Belongs to the binding-protein-dependent transport system permease family
F6X00_RS17690	COG1879	ABC-type sugar transport system periplasmic component
F6X00_RS17695	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F6X00_RS17700	COG1609	Transcriptional regulator
F6X00_RS17705	COG0784	Response regulator, receiver
F6X00_RS17705	COG0835	chemotaxis
F6X00_RS17715	COG0456	acetyltransferase
F6X00_RS17730	COG1366	Belongs to the anti-sigma-factor antagonist family
F6X00_RS17740	COG2172	sigma factor antagonist activity
F6X00_RS17755	COG3437	response regulator, receiver
F6X00_RS17760	COG0420	3'-5' exonuclease activity
F6X00_RS17765	COG0419	ATPase involved in DNA repair
F6X00_RS17775	COG0583	DNA-binding transcription factor activity
F6X00_RS17795	COG4964	Belongs to the GSP D family
F6X00_RS17880	COG0471	metal ion transport
F6X00_RS17885	COG3290	protein histidine kinase activity
F6X00_RS17895	COG0110	maltose O-acetyltransferase activity
F6X00_RS17915	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F6X00_RS17920	COG4605	iron ion homeostasis
F6X00_RS17925	COG4604	ABC transporter, ATP-binding protein
F6X00_RS17930	COG0789	Transcriptional regulator
F6X00_RS17960	COG1289	transmembrane transporter activity
F6X00_RS17965	COG0210	DNA helicase
F6X00_RS17970	COG1803	Methylglyoxal synthase
F6X00_RS17975	COG1879	ABC-type sugar transport system periplasmic component
F6X00_RS18000	COG1262	PFAM Formylglycine-generating sulfatase enzyme
F6X00_RS18005	COG3005	denitrification pathway
F6X00_RS18030	COG0513	Belongs to the DEAD box helicase family
F6X00_RS18040	COG5001	Diguanylate cyclase
F6X00_RS18040	COG1716	ATPase activity
F6X00_RS18065	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
F6X00_RS18080	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
F6X00_RS18085	COG0513	Belongs to the DEAD box helicase family
F6X00_RS18090	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
F6X00_RS18115	COG3335	DDE superfamily endonuclease
F6X00_RS18135	COG3706	GGDEF domain
F6X00_RS18280	COG0210	DNA helicase
F6X00_RS18295	COG3550	peptidyl-serine autophosphorylation
F6X00_RS18300	COG3119	arylsulfatase activity
F6X00_RS18310	COG3119	arylsulfatase activity
F6X00_RS18315	COG0641	radical SAM
F6X00_RS18320	COG0714	Associated with various cellular activities
F6X00_RS18355	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
F6X00_RS18365	COG0641	radical SAM
F6X00_RS18395	COG2814	Major facilitator Superfamily
F6X00_RS18425	COG0583	DNA-binding transcription factor activity
F6X00_RS18430	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
F6X00_RS18445	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
F6X00_RS18455	COG1132	(ABC) transporter
F6X00_RS18465	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
F6X00_RS18465	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
F6X00_RS18470	COG0509	glycine decarboxylation via glycine cleavage system
F6X00_RS18475	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
F6X00_RS18520	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F6X00_RS18520	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
F6X00_RS18520	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F6X00_RS18525	COG1105	Belongs to the carbohydrate kinase PfkB family
F6X00_RS18530	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
F6X00_RS18530	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
F6X00_RS18535	COG1609	Transcriptional regulator
F6X00_RS18560	COG0469	pyruvate kinase activity
F6X00_RS18565	COG2271	Major facilitator Superfamily
F6X00_RS18575	COG4191	Histidine kinase
F6X00_RS18585	COG1979	alcohol dehydrogenase
F6X00_RS18590	COG2207	Transcriptional regulator
F6X00_RS18600	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
F6X00_RS18605	COG2759	Belongs to the formate--tetrahydrofolate ligase family
F6X00_RS18610	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F6X00_RS18630	COG0546	phosphoglycolate phosphatase activity
F6X00_RS18645	COG0513	Belongs to the DEAD box helicase family
F6X00_RS18660	COG3038	cytochrome b561
F6X00_RS18665	COG2353	YceI-like domain
F6X00_RS18670	COG2116	formate transmembrane transporter activity
F6X00_RS18675	COG0583	DNA-binding transcription factor activity
F6X00_RS18685	COG3593	DNA synthesis involved in DNA repair
F6X00_RS18690	COG0737	Belongs to the 5'-nucleotidase family
F6X00_RS18695	COG0861	Integral membrane protein TerC family
F6X00_RS18725	COG2267	carboxylic ester hydrolase activity
F6X00_RS18730	COG2067	long-chain fatty acid transport protein
F6X00_RS18745	COG2050	protein possibly involved in aromatic compounds catabolism
F6X00_RS18755	COG4533	DNA binding
F6X00_RS18765	COG0366	Alpha amylase catalytic
F6X00_RS18770	COG0583	DNA-binding transcription factor activity
F6X00_RS18790	COG0484	heat shock protein binding
F6X00_RS18805	COG5001	Diguanylate cyclase
F6X00_RS18805	COG1716	ATPase activity
F6X00_RS18810	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
F6X00_RS18820	COG4181	ATPase activity
F6X00_RS18825	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
F6X00_RS18830	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F6X00_RS18830	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
F6X00_RS18835	COG1984	allophanate hydrolase subunit 2
F6X00_RS18840	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
F6X00_RS18855	COG3447	MASE1 domain protein
F6X00_RS18855	COG5002	protein histidine kinase activity
F6X00_RS18855	COG5001	Diguanylate cyclase
F6X00_RS18865	COG0583	DNA-binding transcription factor activity
F6X00_RS18870	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F6X00_RS18870	COG0045	succinate-CoA ligase (ADP-forming) activity
F6X00_RS18870	COG1042	CoA-binding domain protein
F6X00_RS18880	COG1181	Belongs to the D-alanine--D-alanine ligase family
F6X00_RS18890	COG0023	Translation Initiation Factor
F6X00_RS19185	COG3140	Belongs to the UPF0181 family
F6X00_RS19200	COG0745	RESPONSE REGULATOR receiver
F6X00_RS19210	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
F6X00_RS19215	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
F6X00_RS19230	COG3706	GGDEF domain
F6X00_RS19240	COG0745	RESPONSE REGULATOR receiver
F6X00_RS19250	COG1846	Transcriptional regulator
F6X00_RS19255	COG0697	spore germination
F6X00_RS19265	COG4149	molybdate abc transporter
F6X00_RS19270	COG0725	ABC transporter, periplasmic molybdate-binding protein
F6X00_RS19290	COG0189	ligase activity
F6X00_RS19290	COG4067	protein conserved in archaea
F6X00_RS19300	COG0840	transmembrane signaling receptor activity
F6X00_RS19305	COG0602	queuosine metabolic process
F6X00_RS19310	COG1328	CTP reductase activity
F6X00_RS19365	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
F6X00_RS19370	COG3118	belongs to the thioredoxin family
F6X00_RS19375	COG0477	Major facilitator Superfamily
F6X00_RS19385	COG0534	Mate efflux family protein
F6X00_RS19405	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
F6X00_RS19420	COG0848	biopolymer transport protein
F6X00_RS19425	COG0811	peptide transport
F6X00_RS19430	COG0811	peptide transport
F6X00_RS19465	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
F6X00_RS19500	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
F6X00_RS19510	COG2203	Gaf domain
F6X00_RS19510	COG4251	negative regulation of phosphorylation
F6X00_RS19510	COG5001	Diguanylate cyclase
F6X00_RS19510	COG3706	GGDEF domain
F6X00_RS19520	COG0010	Belongs to the arginase family
F6X00_RS19525	COG0513	Belongs to the DEAD box helicase family
F6X00_RS19535	COG0523	cobalamin synthesis protein
F6X00_RS19545	COG2199	diguanylate cyclase activity
F6X00_RS19560	COG2146	nitrite reductase [NAD(P)H] activity
F6X00_RS19560	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
F6X00_RS19565	COG1116	anion transmembrane transporter activity
F6X00_RS19570	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F6X00_RS19575	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
F6X00_RS19575	COG1116	anion transmembrane transporter activity
F6X00_RS19595	COG1648	precorrin-2 dehydrogenase activity
F6X00_RS19595	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
F6X00_RS19600	COG0243	molybdopterin cofactor binding
F6X00_RS19605	COG0456	acetyltransferase
F6X00_RS19605	COG1214	PFAM Peptidase M22, glycoprotease
F6X00_RS19610	COG0366	Alpha amylase catalytic
F6X00_RS19615	COG0840	transmembrane signaling receptor activity
F6X00_RS19620	COG0840	transmembrane signaling receptor activity
F6X00_RS19635	COG2271	Major facilitator Superfamily
F6X00_RS19640	COG0584	glycerophosphoryl diester phosphodiesterase
F6X00_RS19645	COG0312	modulator of DNA gyrase
F6X00_RS19650	COG0312	modulator of DNA gyrase
F6X00_RS19660	COG3069	C4-dicarboxylate transmembrane transporter activity
F6X00_RS19665	COG1704	LemA family
F6X00_RS19670	COG0501	Belongs to the peptidase M48B family
F6X00_RS19680	COG3209	COG3209 Rhs family protein
F6X00_RS19750	COG3501	Rhs element vgr protein
F6X00_RS19805	COG0631	protein serine/threonine phosphatase activity
F6X00_RS19840	COG0515	serine threonine protein kinase
F6X00_RS19840	COG2815	serine threonine protein kinase
F6X00_RS19860	COG3530	Putative quorum-sensing-regulated virulence factor
F6X00_RS19880	COG2154	pterin-4-alpha-carbinolamine dehydratase
F6X00_RS19885	COG3186	Phenylalanine-4-hydroxylase
F6X00_RS19890	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
F6X00_RS19920	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
F6X00_RS19930	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F6X00_RS19930	COG4191	Histidine kinase
F6X00_RS19935	COG0784	Response regulator, receiver
F6X00_RS19935	COG3437	response regulator, receiver
F6X00_RS19990	COG3064	Membrane
F6X00_RS19990	COG1073	alpha beta
F6X00_RS19990	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
F6X00_RS19995	COG2994	toxin metabolic process
F6X00_RS20035	COG1028	Short-chain dehydrogenase reductase Sdr
F6X00_RS20045	COG1024	Enoyl-CoA hydratase
F6X00_RS20050	COG1024	Enoyl-CoA hydratase
F6X00_RS20055	COG1960	acyl-CoA dehydrogenase activity
F6X00_RS20065	COG0183	Belongs to the thiolase family
F6X00_RS20075	COG1960	acyl-CoA dehydrogenase activity
F6X00_RS20080	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
F6X00_RS20085	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
F6X00_RS20105	COG1278	Cold shock
F6X00_RS20120	COG1309	transcriptional regulator
F6X00_RS20125	COG2130	NADP-dependent
F6X00_RS20145	COG2197	response regulator
F6X00_RS20150	COG3851	Histidine kinase
F6X00_RS20155	COG2271	Major facilitator Superfamily
F6X00_RS20160	COG1482	cell wall glycoprotein biosynthetic process
F6X00_RS20170	COG2203	Gaf domain
F6X00_RS20170	COG2199	diguanylate cyclase activity
F6X00_RS20180	COG3036	rescue of stalled ribosome
F6X00_RS20185	COG1278	Cold shock
F6X00_RS20215	COG0545	Peptidyl-prolyl cis-trans isomerase
F6X00_RS20220	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
F6X00_RS20225	COG0840	transmembrane signaling receptor activity
F6X00_RS20245	COG2195	Cleaves the N-terminal amino acid of tripeptides
F6X00_RS20255	COG4989	oxidoreductase activity
F6X00_RS20270	COG0038	chloride channel
F6X00_RS20280	COG1914	H( )-stimulated, divalent metal cation uptake system
F6X00_RS20285	COG0302	gtp cyclohydrolase
F6X00_RS20290	COG0303	'Molybdopterin
F6X00_RS20295	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
F6X00_RS20305	COG2897	thiosulfate sulfurtransferase activity
F6X00_RS20325	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
F6X00_RS20330	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
F6X00_RS20345	COG0840	transmembrane signaling receptor activity
F6X00_RS20350	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
F6X00_RS20355	COG2885	chlorophyll binding
F6X00_RS20360	COG0109	protoheme IX farnesyltransferase activity
F6X00_RS20365	COG1612	heme a metabolic process
F6X00_RS20390	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
F6X00_RS20395	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
F6X00_RS20400	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
F6X00_RS20405	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
F6X00_RS20415	COG1280	lysine exporter protein (LysE YggA)
F6X00_RS20440	COG1846	Transcriptional regulator
F6X00_RS20445	COG1764	response to oxidative stress
F6X00_RS20455	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
F6X00_RS20470	COG0697	spore germination
F6X00_RS20485	COG2814	Major facilitator Superfamily
F6X00_RS20490	COG0583	DNA-binding transcription factor activity
F6X00_RS20495	COG2203	Gaf domain
F6X00_RS20495	COG3706	GGDEF domain
F6X00_RS20495	COG4251	negative regulation of phosphorylation
F6X00_RS20495	COG5001	Diguanylate cyclase
F6X00_RS20500	COG0251	oxidation-reduction process
F6X00_RS20515	COG4145	pantothenate transmembrane transporter activity
F6X00_RS20525	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
F6X00_RS20535	COG1737	Transcriptional regulator
F6X00_RS20535	COG0837	glucose binding
F6X00_RS20545	COG1131	(ABC) transporter
F6X00_RS20550	COG0842	Transport permease protein
F6X00_RS20580	COG1846	Transcriptional regulator
F6X00_RS20590	COG0513	Belongs to the DEAD box helicase family
F6X00_RS20615	COG3568	Endonuclease Exonuclease Phosphatase
F6X00_RS20630	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
F6X00_RS20660	COG0516	GMP reductase activity
F6X00_RS20670	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
F6X00_RS20670	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
F6X00_RS20690	COG2197	response regulator
F6X00_RS20695	COG3850	Histidine kinase
F6X00_RS20700	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
F6X00_RS20710	COG0243	molybdopterin cofactor binding
F6X00_RS20720	COG3005	denitrification pathway
F6X00_RS20730	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
F6X00_RS20735	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
F6X00_RS20740	COG1737	Transcriptional regulator
F6X00_RS20745	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F6X00_RS20750	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
F6X00_RS20755	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
F6X00_RS20760	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
F6X00_RS20765	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
F6X00_RS20770	COG1940	carbohydrate kinase activity
F6X00_RS20775	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
F6X00_RS20795	COG0183	Belongs to the thiolase family
F6X00_RS20805	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
F6X00_RS20810	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
F6X00_RS20850	COG1879	ABC-type sugar transport system periplasmic component
F6X00_RS20860	COG2827	Endonuclease containing a URI domain
F6X00_RS20865	COG3132	Protein of unknown function, DUF480
F6X00_RS20875	COG2926	Belongs to the UPF0265 family
F6X00_RS20885	COG0534	Mate efflux family protein
F6X00_RS20890	COG2205	protein histidine kinase activity
F6X00_RS20890	COG0784	Response regulator, receiver
F6X00_RS20890	COG5002	protein histidine kinase activity
F6X00_RS20915	COG0583	DNA-binding transcription factor activity
F6X00_RS20940	COG1522	sequence-specific DNA binding
F6X00_RS20945	COG0531	amino acid
F6X00_RS20950	COG0121	glutamine amidotransferase
F6X00_RS20965	COG2205	protein histidine kinase activity
F6X00_RS20970	COG0745	RESPONSE REGULATOR receiver
F6X00_RS21005	COG2067	long-chain fatty acid transport protein
F6X00_RS21015	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F6X00_RS21035	COG2239	Acts as a magnesium transporter
F6X00_RS21045	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
F6X00_RS21050	COG0402	S-adenosylhomocysteine deaminase activity
F6X00_RS21055	COG1067	ATP-dependent peptidase activity
F6X00_RS21065	COG4172	Belongs to the ABC transporter superfamily
F6X00_RS21070	COG1505	serine-type exopeptidase activity
F6X00_RS21075	COG0583	DNA-binding transcription factor activity
F6X00_RS21080	COG1620	l-lactate permease
F6X00_RS21090	COG1139	Iron-sulfur cluster binding protein
F6X00_RS21115	COG2814	Major facilitator Superfamily
F6X00_RS21155	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
F6X00_RS21170	COG3015	lipoprotein NlpE involved in copper resistance
F6X00_RS21175	COG1126	abc transporter atp-binding protein
F6X00_RS21180	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F6X00_RS21185	COG4215	(ABC) transporter
F6X00_RS21190	COG4160	amino acid transport
F6X00_RS21205	COG5001	Diguanylate cyclase
F6X00_RS21205	COG5002	protein histidine kinase activity
F6X00_RS21210	COG2755	lipolytic protein G-D-S-L family
F6X00_RS21225	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F6X00_RS21255	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
F6X00_RS21260	COG1028	Short-chain dehydrogenase reductase Sdr
F6X00_RS21265	COG1169	isochorismate synthase
F6X00_RS21270	COG1021	2,3-dihydroxybenzoate-AMP ligase
F6X00_RS21290	COG1021	2,3-dihydroxybenzoate-AMP ligase
F6X00_RS21300	COG4607	ABC-type enterochelin transport system periplasmic component
F6X00_RS21305	COG1629	transport
F6X00_RS21305	COG4774	siderophore transport
F6X00_RS21315	COG0189	ligase activity
F6X00_RS21320	COG4067	protein conserved in archaea
F6X00_RS21320	COG0189	ligase activity
F6X00_RS21345	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F6X00_RS21360	COG3033	Beta-eliminating lyase
F6X00_RS21365	COG0814	amino acid
F6X00_RS21370	COG0488	(ABC) transporter
F6X00_RS21385	COG1609	Transcriptional regulator
F6X00_RS21390	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
F6X00_RS21415	COG1253	flavin adenine dinucleotide binding
F6X00_RS21425	COG1012	belongs to the aldehyde dehydrogenase family
F6X00_RS21430	COG3284	Transcriptional regulator
F6X00_RS21445	COG0625	glutathione transferase activity
F6X00_RS21455	COG0384	phenazine biosynthesis protein PhzF
F6X00_RS21460	COG2197	response regulator
F6X00_RS21465	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
F6X00_RS21470	COG0673	inositol 2-dehydrogenase activity
F6X00_RS21495	COG2015	COG2015, Alkyl sulfatase and related hydrolases
F6X00_RS21505	COG0583	DNA-binding transcription factor activity
F6X00_RS21510	COG2194	sulfuric ester hydrolase activity
F6X00_RS21520	COG0798	PFAM Bile acid sodium symporter
F6X00_RS21525	COG0640	Transcriptional regulator
F6X00_RS21545	COG0583	DNA-binding transcription factor activity
F6X00_RS21560	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
F6X00_RS21565	COG0700	Nucleoside recognition
F6X00_RS21570	COG3366	ferrous iron transmembrane transporter activity
F6X00_RS21580	COG0366	Alpha amylase catalytic
F6X00_RS21585	COG0823	Involved in the tonB-independent uptake of proteins
F6X00_RS21590	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
F6X00_RS21620	COG0800	Aldolase
F6X00_RS21625	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F6X00_RS21630	COG0697	spore germination
F6X00_RS21640	COG0583	DNA-binding transcription factor activity
F6X00_RS21650	COG1917	Cupin 2, conserved barrel domain protein
F6X00_RS21660	COG1028	Short-chain dehydrogenase reductase Sdr
F6X00_RS21705	COG0668	transmembrane transport
F6X00_RS21735	COG0494	nUDIX hydrolase
F6X00_RS21740	COG1881	PFAM PEBP family protein
F6X00_RS21745	COG2207	Transcriptional regulator
F6X00_RS21750	COG3046	protein related to deoxyribodipyrimidine photolyase
F6X00_RS21775	COG0454	-acetyltransferase
F6X00_RS21780	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
F6X00_RS21805	COG1858	cytochrome C peroxidase
F6X00_RS21860	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
F6X00_RS21870	COG0583	DNA-binding transcription factor activity
F6X00_RS21890	COG0513	Belongs to the DEAD box helicase family
F6X00_RS21925	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
F6X00_RS21935	COG1357	PFAM Pentapeptide repeats (8 copies)
F6X00_RS21955	COG3437	response regulator, receiver
F6X00_RS21965	COG0579	oxidoreductase
F6X00_RS21995	COG2015	COG2015, Alkyl sulfatase and related hydrolases
F6X00_RS22010	COG2205	protein histidine kinase activity
F6X00_RS22045	COG3706	GGDEF domain
F6X00_RS22060	COG2176	DNA-directed DNA polymerase activity
F6X00_RS22065	COG1136	(ABC) transporter
F6X00_RS22065	COG0577	efflux transmembrane transporter activity
F6X00_RS22070	COG1136	(ABC) transporter
F6X00_RS22070	COG0577	efflux transmembrane transporter activity
F6X00_RS22100	COG1120	ATPase activity
F6X00_RS22105	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
F6X00_RS22135	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
F6X00_RS22140	COG3716	PTS system mannose fructose sorbose family IID component
F6X00_RS22150	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F6X00_RS22155	COG2222	sugar isomerase
F6X00_RS22165	COG1349	DNA-binding transcription factor activity
F6X00_RS22170	COG1349	DNA-binding transcription factor activity
F6X00_RS22175	COG0697	spore germination
F6X00_RS22180	COG2207	Transcriptional regulator
F6X00_RS22195	COG2015	COG2015, Alkyl sulfatase and related hydrolases
F6X00_RS22220	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
F6X00_RS22225	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
F6X00_RS22245	COG0840	transmembrane signaling receptor activity
F6X00_RS22260	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
F6X00_RS22290	COG2258	MOSC domain
F6X00_RS22320	COG0513	Belongs to the DEAD box helicase family
F6X00_RS22330	COG2186	Transcriptional regulator
F6X00_RS22340	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
F6X00_RS22350	COG0246	Mannitol dehydrogenase
F6X00_RS22355	COG1904	glucuronate isomerase
F6X00_RS22360	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F6X00_RS22365	COG0800	Aldolase
F6X00_RS22380	COG1028	Short-chain dehydrogenase reductase Sdr
F6X00_RS22385	COG2999	glutathione oxidoreductase activity
F6X00_RS22390	COG1902	pentaerythritol trinitrate reductase activity
F6X00_RS22420	COG0561	phosphatase activity
F6X00_RS22425	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
F6X00_RS22430	COG3623	hexulose-6-phosphate isomerase
F6X00_RS22445	COG1132	(ABC) transporter
F6X00_RS22465	COG5426	von Willebrand factor, type A
F6X00_RS22475	COG1028	Short-chain dehydrogenase reductase Sdr
F6X00_RS22485	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
F6X00_RS22490	COG0659	secondary active sulfate transmembrane transporter activity
F6X00_RS22515	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F6X00_RS22520	COG0601	transmembrane transport
F6X00_RS22525	COG0747	negative chemotaxis
F6X00_RS22535	COG3119	arylsulfatase activity
F6X00_RS22540	COG0641	radical SAM
F6X00_RS22545	COG3119	arylsulfatase activity
F6X00_RS22550	COG3119	arylsulfatase activity
F6X00_RS22555	COG5492	domain, Protein
F6X00_RS22580	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
F6X00_RS22605	COG0259	pyridoxamine-phosphate oxidase activity
F6X00_RS22615	COG2204	response regulator
F6X00_RS22645	COG3069	C4-dicarboxylate transmembrane transporter activity
F6X00_RS22650	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
F6X00_RS22665	COG0459	protein refolding
F6X00_RS22670	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
F6X00_RS22675	COG0110	maltose O-acetyltransferase activity
F6X00_RS22690	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
F6X00_RS22690	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
F6X00_RS22695	COG1737	Transcriptional regulator
F6X00_RS22700	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
F6X00_RS22705	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F6X00_RS22705	COG1263	PTS System
F6X00_RS22715	COG2200	EAL domain
F6X00_RS22715	COG2199	diguanylate cyclase activity
F6X00_RS22715	COG2203	Gaf domain
F6X00_RS22720	COG0406	alpha-ribazole phosphatase activity
F6X00_RS22735	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
F6X00_RS22780	COG0840	transmembrane signaling receptor activity
F6X00_RS22785	COG2201	protein-glutamate methylesterase activity
F6X00_RS22795	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
F6X00_RS22800	COG0840	transmembrane signaling receptor activity
F6X00_RS22805	COG0835	chemotaxis
F6X00_RS22820	COG0745	RESPONSE REGULATOR receiver
F6X00_RS22830	COG1444	tRNA N-acetyltransferase activity
F6X00_RS22855	COG4608	Belongs to the ABC transporter superfamily
F6X00_RS22860	COG0444	Belongs to the ABC transporter superfamily
F6X00_RS22870	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
F6X00_RS22870	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
F6X00_RS22890	COG0217	transcriptional regulatory protein
F6X00_RS22900	COG0583	DNA-binding transcription factor activity
F6X00_RS22910	COG1136	(ABC) transporter
F6X00_RS22915	COG4591	ABC-type transport system involved in lipoprotein release permease component
F6X00_RS22930	COG3275	phosphorelay sensor kinase activity
F6X00_RS22950	COG0786	glutamate:sodium symporter activity
F6X00_RS22955	COG0786	glutamate:sodium symporter activity
F6X00_RS22965	COG0363	glucosamine-6-phosphate deaminase activity
F6X00_RS22980	COG0189	ligase activity
F6X00_RS23000	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
F6X00_RS23005	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
F6X00_RS23010	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
F6X00_RS23025	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
F6X00_RS23035	COG1309	transcriptional regulator
F6X00_RS23055	COG3123	guanosine phosphorylase activity
F6X00_RS23060	COG1741	Belongs to the pirin family
F6X00_RS23070	COG5001	Diguanylate cyclase
F6X00_RS23075	COG3706	GGDEF domain
F6X00_RS23125	COG1982	Orn Lys Arg decarboxylase major
F6X00_RS23130	COG0531	amino acid
F6X00_RS23140	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
F6X00_RS23145	COG1162	GTPase activity
F6X00_RS23150	COG2847	Copper chaperone PCu(A)C
F6X00_RS23155	COG1999	signal sequence binding
F6X00_RS23170	COG2909	trisaccharide binding
F6X00_RS23175	COG0058	SHG alpha-glucan phosphorylase activity
F6X00_RS23180	COG1640	4-alpha-glucanotransferase
F6X00_RS23185	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
F6X00_RS23190	COG0840	transmembrane signaling receptor activity
F6X00_RS23195	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
F6X00_RS23255	COG1012	belongs to the aldehyde dehydrogenase family
F6X00_RS23260	COG0625	glutathione transferase activity
F6X00_RS23265	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
F6X00_RS23270	COG1283	sodium-dependent phosphate transmembrane transporter activity
F6X00_RS23275	COG0612	Peptidase, M16
F6X00_RS23285	COG0583	DNA-binding transcription factor activity
F6X00_RS23290	COG0583	DNA-binding transcription factor activity
F6X00_RS23300	COG0387	Pfam Sodium calcium exchanger
F6X00_RS23305	COG0586	Pfam SNARE associated Golgi protein
F6X00_RS23315	COG0642	Histidine kinase
F6X00_RS23345	COG2199	diguanylate cyclase activity
F6X00_RS23360	COG1609	Transcriptional regulator
F6X00_RS23375	COG0395	ABC-type sugar transport system, permease component
F6X00_RS23385	COG3842	ATPase activity
F6X00_RS23390	COG1609	Transcriptional regulator
F6X00_RS23400	COG0747	negative chemotaxis
F6X00_RS23410	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F6X00_RS23415	COG0444	Belongs to the ABC transporter superfamily
F6X00_RS23420	COG4608	Belongs to the ABC transporter superfamily
F6X00_RS23430	COG1609	Transcriptional regulator
F6X00_RS23445	COG4580	involved in the transport of maltose and maltodextrins
F6X00_RS23455	COG1472	Belongs to the glycosyl hydrolase 3 family
F6X00_RS23460	COG0534	Mate efflux family protein
F6X00_RS23470	COG1566	PFAM secretion protein HlyD family protein
F6X00_RS23500	COG0564	pseudouridine synthase activity
F6X00_RS23525	COG1609	Transcriptional regulator
F6X00_RS23535	COG1129	ABC transporter
F6X00_RS23555	COG2211	Major facilitator Superfamily
F6X00_RS23560	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
F6X00_RS23565	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
F6X00_RS23570	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
F6X00_RS23600	COG1482	cell wall glycoprotein biosynthetic process
F6X00_RS23605	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F6X00_RS23605	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F6X00_RS23605	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
F6X00_RS23610	COG2207	Transcriptional regulator
F6X00_RS23620	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F6X00_RS23625	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F6X00_RS23650	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F6X00_RS23670	COG3383	formate dehydrogenase (NAD+) activity
F6X00_RS23680	COG1609	Transcriptional regulator
F6X00_RS23685	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F6X00_RS23685	COG1263	PTS System
F6X00_RS23690	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
F6X00_RS23695	COG1482	cell wall glycoprotein biosynthetic process
F6X00_RS23700	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
F6X00_RS23705	COG0583	DNA-binding transcription factor activity
F6X00_RS23755	COG0583	DNA-binding transcription factor activity
F6X00_RS23760	COG1733	regulation of RNA biosynthetic process
F6X00_RS23780	COG0137	argininosuccinate synthase activity
F6X00_RS23790	COG1301	dicarboxylic acid transport
F6X00_RS23835	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
F6X00_RS23840	COG2175	clavaminate synthase activity
F6X00_RS23870	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F6X00_RS23880	COG3706	GGDEF domain
F6X00_RS23895	COG2356	endonuclease I
F6X00_RS23910	COG1368	sulfuric ester hydrolase activity
F6X00_RS23915	COG2194	sulfuric ester hydrolase activity
F6X00_RS23920	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
F6X00_RS23925	COG2205	protein histidine kinase activity
F6X00_RS23930	COG0745	RESPONSE REGULATOR receiver
F6X00_RS23945	COG4221	oxidoreductase activity
F6X00_RS23970	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
F6X00_RS23975	COG0076	glutamate decarboxylase activity
F6X00_RS23980	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
F6X00_RS23990	COG0561	phosphatase activity
F6X00_RS24005	COG0671	phosphoesterase, PA-phosphatase related
F6X00_RS24010	COG0351	phosphomethylpyrimidine kinase
F6X00_RS24075	COG2814	Major facilitator Superfamily
F6X00_RS24090	COG0039	L-malate dehydrogenase activity
F6X00_RS24095	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
F6X00_RS24100	COG4771	TonB-dependent receptor
F6X00_RS24120	COG0393	Putative heavy-metal-binding
F6X00_RS24135	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
F6X00_RS24145	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
F6X00_RS24165	COG0753	catalase activity
F6X00_RS24180	COG0346	lactoylglutathione lyase activity
F6X00_RS24190	COG2211	Major facilitator Superfamily
F6X00_RS24205	COG3240	lipase activity
F6X00_RS24250	COG3646	Phage regulatory protein
F6X00_RS24255	COG0582	viral genome integration into host DNA
F6X00_RS24315	COG4626	Terminase
F6X00_RS24315	COG1802	Transcriptional regulator
F6X00_RS24335	COG1403	HNH endonuclease
F6X00_RS24380	COG3772	lysozyme
F6X00_RS24410	COG1030	water channel activity
F6X00_RS24495	COG1063	alcohol dehydrogenase
F6X00_RS24570	COG3040	lipid binding
F6X00_RS24605	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
F6X00_RS24615	COG2197	response regulator
F6X00_RS24635	COG0784	Response regulator, receiver
F6X00_RS24635	COG2205	protein histidine kinase activity
F6X00_RS24640	COG3111	PFAM Bacterial OB fold (BOF) protein
F6X00_RS24650	COG2274	protein secretion by the type I secretion system
F6X00_RS24775	COG1192	Involved in chromosome partitioning
F6X00_RS24845	COG1192	Involved in chromosome partitioning
F6X00_RS24890	COG3692	DNA binding
F6X00_RS24975	COG3657	addiction module killer protein
F6X00_RS24980	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD